Basic Information:

Complex ID	CMCS00183
Complex	PDZD8; RAB7A; ZFYVE27
Subunit Number	3
Membrane Contact Site	ER-Endosome; Endosome-ER
Species	Human
Identified PPI in BioGRID	PDZD8-RAB7A(HTP: 0.00); RAB7A-ZFYVE27(HTP: 0.02)

Subunit Information:

Subunit	Symbol	Uniprot ID	Subcellular location	More
subunit:1	PDZD8	Q8NEN9	ER	more
subunit:2	RAB7A	P51149	Endosome	more
subunit:3	ZFYVE27	Q5T4F4	ER	more

References:

Pubmed ID	32686675
DOI	10.1038/s41467-020-17451-7
Description	Our results identify the ER membrane proteins, PDZD8 and Protrudin, together with the late endosomal protein Rab7, as components of an ER-late endosome MCS in mammalian cells.
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