Basic Information:

Complex ID	CMCS00078
Complex	Sigmar1; Itpr3
Subunit Number	2
Membrane Contact Site	ER-MT; MT-ER
Species	Mouse
Identified PPI in BioGRID	/

Subunit Information:

Subunit	Symbol	Uniprot ID	Subcellular location	More
subunit:1	Sigmar1	O55242	ER; MT	more
subunit:2	Itpr3	P70227	ER	more

References:

Pubmed ID	27821430
DOI	10.15252/emmm.201606403
Description	All these data indicate that the Sig1R activation that regulates IP3R3‐mediated intracellular Ca2+ flux at the MAM is crucial to prevent MAM disruption in motor neurons both in vitro and in vivo.
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