Detail information of Complex

Basic Information:

Complex ID CMCS00072
Complex MOSPD2; CERT1
Subunit Number 2
Membrane Contact Site ER-Endosome; Endosome-ER
Species Human
Identified PPI in BioGRID /

Subunit Information:

Subunit Symbol Uniprot ID Subcellular location More
subunit:1 MOSPD2 Q8NHP6 ER more
subunit:2 CERT1 Q9Y5P4 Endosome more

References:

Pubmed ID 33124732
DOI 10.15252/embj.2019104369
Description The endoplasmic reticulum possesses three major receptors, VAP‐A, VAP‐B, and MOSPD2, which interact with proteins at the surface of other organelles to build contacts; onventional FFATs (illustrated here with STARD11/CERT) which allow the formation of a stable complex between VAPs/MOSPD2 and thus the formation of MCSs.
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