Basic Information:

Symbol	CERT1
Synonyms	CERT; COL4A3BP; STARD11
Protein Name	Ceramide transfer protein (hCERT) (Collagen type IV alpha-3-binding protein) (Goodpasture antigen-binding protein) (GPBP) (START domain-containing protein 11) (StARD11) (StAR-related lipid transfer protein 11)
Species	Human
Entrez ID	10087
Uniprot ID	Q9Y5P4
Membrane Contact Site	ER-Endosome; Endosome-ER
Location (from literature)	Endosome
Cell line/Tissue	HeLa cells
Experimental Method	Low throughput experimental methods
Protein Sequence
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Complex Information:

Complex ID	Subunit of complex	Subcellular location	Species	More
CMCS00071	VAPA; VAPB; CERT1	ER-Endosome; Endosome-ER	Human	more
CMCS00072	MOSPD2; CERT1	ER-Endosome; Endosome-ER	Human	more

Expression Overview of CERT1:

Homology Information of CERT1:

Uniprot ID	Q9Y5P4
EggNOG	KOG1739
HOGENOM	CLU_017289_0_0_1
OrthoDB	5489052at2759
TreeFam	TF106160
GeneTree	ENSGT00940000155123

References:

Pubmed ID	33124732
DOI	10.15252/embj.2019104369
Description	The endoplasmic reticulum possesses three major receptors, VAP‐A, VAP‐B, and MOSPD2, which interact with proteins at the surface of other organelles to build contacts; onventional FFATs (illustrated here with STARD11/CERT) which allow the formation of a stable complex between VAPs/MOSPD2 and thus the formation of MCSs.
Description of experimental evidence	The protein was validated by pull‐down assays, immunoprecipitation,SDS–PAGE, western blot, CIP treatment, coomassie blue staining, mass spectrometry analysis, immunofluorescence and colocalization analysis in HeLa cells.
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