Basic Information:
Complex ID | CMCS00071 |
Complex | VAPA; VAPB; CERT1 |
Subunit Number | 3 |
Membrane Contact Site |
ER-Endosome; Endosome-ER
|
Species | Human |
Identified PPI in BioGRID | VAPA-VAPB(LTP) |
Subunit Information:
Subunit | Symbol | Uniprot ID | Subcellular location | More |
subunit:1 | VAPA | Q9P0L0 | ER | more |
subunit:2 | VAPB | O95292 | ER | more |
subunit:3 | CERT1 | Q9Y5P4 | Endosome | more |
References:
Pubmed ID | 33124732 |
DOI | 10.15252/embj.2019104369 |
Description | The endoplasmic reticulum possesses three major receptors, VAP‐A, VAP‐B, and MOSPD2, which interact with proteins at the surface of other organelles to build contacts; onventional FFATs (illustrated here with STARD11/CERT) which allow the formation of a stable complex between VAPs/MOSPD2 and thus the formation of MCSs. |
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