Detail information of Complex

Basic Information:

Complex ID CMCS00177
Complex Vdac1; Gsk3b
Subunit Number 2
Membrane Contact Site ER-MT; MT-ER
Species Mouse
Identified PPI in BioGRID /

Subunit Information:

Subunit Symbol Uniprot ID Subcellular location More
subunit:1 Gsk3b Q9WV60 ER more
subunit:2 Vdac1 Q60932 MT more

References:

Pubmed ID 29523440
DOI 10.1016/j.immuni.2018.02.012
Description Rapid activation of Akt by mTORC2 led to inhibition of Gsk-3b at mitochondria-ER junctions, enabling recruitment of hexokinase I (HK-I) to the mitochondrial channel, VDAC.
More related results

Contact zhy1001@alu.uestc.edu.cn or yangzhang@cdutcm.edu.cn
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