Detail information of Complex

Basic Information:

Complex ID CMCS00167
Complex OSBPL10; OSBPL9; VAPA; VAPB; PI(4)P
Subunit Number 5
Membrane Contact Site ER-Endosome; Endosome-ER
Species Human
Identified PPI in BioGRID VAPB-OSBPL10; OSBPL9-OSBPL10; OSBPL9-VAPB; VAPA-OSBPL10; OSBPL9-VAPA; SPAST-CHMP1B; VAPA-VAPB

Subunit Information:

Subunit Symbol Uniprot ID Subcellular location More
subunit:1 OSBPL10 Q9BXB5 Endosome more
subunit:2 OSBPL9 Q96SU4 Endosome more
subunit:3 VAPA Q9P0L0 ER more
subunit:4 VAPB O95292 ER more

References:

Pubmed ID 34817532
DOI 10.1083/jcb.202103141
Description ORP10 localizes in a PI4P-dependent manner at ER–endosome membrane contact sites tethered by ORP9 and VAP, where it mediates countertransport of PI4P and PS.
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