Basic Information:

Complex ID	CMCS00167
Complex	OSBPL10; OSBPL9; VAPA; VAPB; PI(4)P
Subunit Number	5
Membrane Contact Site	ER-Endosome; Endosome-ER
Species	Human
Identified PPI in BioGRID	VAPB-OSBPL10(HTP: 1.00); OSBPL9-OSBPL10(HTP: 10.79); OSBPL9-VAPB(HTP: 6.69); VAPA-OSBPL10(HTP: 1.00); OSBPL9-VAPA(HTP: 11.72); SPAST-CHMP1B(LTP); VAPA-VAPB(LTP)

Subunit Information:

Subunit	Symbol	Uniprot ID	Subcellular location	More
subunit:1	OSBPL10	Q9BXB5	Endosome	more
subunit:2	OSBPL9	Q96SU4	Endosome	more
subunit:3	VAPA	Q9P0L0	ER	more
subunit:4	VAPB	O95292	ER	more

References:

Pubmed ID	34817532
DOI	10.1083/jcb.202103141
Description	ORP10 localizes in a PI4P-dependent manner at ER–endosome membrane contact sites tethered by ORP9 and VAP, where it mediates countertransport of PI4P and PS.
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