Basic Information:

Complex ID	CMCS00004
Complex	VAPA; OSBPL1A; sterol; PI(4)P; NPC1
Subunit Number	5
Membrane Contact Site	ER-Endosome; Endosome-ER
Species	Human
Identified PPI in BioGRID	VAPA-OSBPL1A(LTP)

Subunit Information:

Subunit	Symbol	Uniprot ID	Subcellular location	More
subunit:1	VAPA	Q9P0L0	ER	more
subunit:2	OSBPL1A	Q9BXW6	Endosome	more
subunit:3	NPC1	O15118	Endosome	more

References:

Pubmed ID	28564600
DOI	10.1016/j.celrep.2017.05.028
Description	Cholesterol delivery to the ER required the sterol-, phosphatidylinositol 4-phosphate-, and vesicle-associated membrane protein-associated protein (VAP)-binding activities of ORP1L, as well as NPC1 expression.
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