Basic Information:

Complex ID	CMCS00011
Complex	VAPA; VAPB; OSBPL1A
Subunit Number	3
Membrane Contact Site	ER-Endosome; Endosome-ER
Species	Human
Identified PPI in BioGRID	VAPA-VAPB(LTP); VAPB-OSBPL1A(LTP)

Subunit Information:

Subunit	Symbol	Uniprot ID	Subcellular location	More
subunit:1	VAPA	Q9P0L0	ER	more
subunit:2	VAPB	O95292	ER	more
subunit:3	OSBPL1A	Q9BXW6	Endosome	more

References:

Pubmed ID	27270042
DOI	10.1016/j.devcel.2016.05.005
Description	This sterol traffic depends on interaction between ER-localized VAP and endosomal oxysterol-binding protein ORP1L, and is required for the formation of ILVs within the MVB and thus for the spatial regulation of EGFR signaling.
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