Basic Information:

Symbol	Tgm2
Protein Name	Protein-glutamine gamma-glutamyltransferase 2 (EC 2.3.2.13) (Isopeptidase TGM2) (EC 3.4.-.-) (Protein-glutamine deamidase TGM2) (EC 3.5.1.44) (Protein-glutamine dopaminyltransferase TGM2) (EC 2.3.1.-) (Protein-glutamine histaminyltransferase TGM2) (EC 2.3.1.-) (Protein-glutamine noradrenalinyltransferase TGM2) (EC 2.3.1.-) (Protein-glutamine serotonyltransferase TGM2) (EC 2.3.1.-) (Tissue transglutaminase) (tTG) (Transglutaminase II) (TGase II) (Transglutaminase-2) (TG2) (TGase-2) (TGase2)
Species	Mouse
Entrez ID	21817
Uniprot ID	P21981
Membrane Contact Site	ER-MT; MT-ER
Location (from literature)	MT
Cell line/Tissue	Mouse livers; MEFs; Mouse testes
Experimental Method	Low throughput experimental methods
Protein Sequence
More related results

Complex Information:

Complex ID	Subunit of complex	Subcellular location	Species	More
CMCS00161	Tgm2; Vdac1; Itpr1; Hspa9	ER-MT; MT-ER	Mouse	more

Expression Overview of Tgm2:

Homology Information of Tgm2:

Uniprot ID	P21981
EggNOG	ENOG502QUSX
HOGENOM	CLU_013435_1_0_1
OrthoDB	5344745at2759
TreeFam	TF324278
GeneTree	ENSGT01050000244866

References:

Pubmed ID	30590033
DOI	10.1016/j.celrep.2018.11.094
Description	In this study, we demonstrated that TG2 localizes in the MAMs and its presence in the ER-Mitochondrion contact site is essential to maintain the correct structural and functionalhomeostasisof this important cellular regulatory site.
Description of experimental evidence	The protein was validated by western blot analysis, Co-IP and PLA in mouse livers and MEFs.
More related results

Pubmed ID	29785746
DOI	10.1002/pmic.201700478
Description	By Andromeda search engine against the decoy UniProt-mouse database and Swiss-Prot human database, which yielded 2,808 proteins from mouse testes (mT),2,478 proteins from mouse brain (mB) and 2,155 proteins from human testes (hT).
Description of experimental evidence	The protein was validated by TEM and LC -MS/MS analyses in mouse testes.
More related results