Basic Information:

Symbol	Sel1l
Synonyms	Sel1h
Protein Name	Protein sel-1 homolog 1 (Suppressor of lin-12-like protein 1) (Sel-1L)
Species	Mouse
Entrez ID	20338
Uniprot ID	Q9Z2G6
Membrane Contact Site	ER-MT; MT-ER
Location (from literature)	ER
Cell line/Tissue	Brown adipocytes; Mouse testes; Mouse brains
Experimental Method	Low throughput experimental methods
Protein Sequence
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Complex Information:

Complex ID	Subunit of complex	Subcellular location	Species	More
CMCS00079	Sigmar1; Sel1l; Syvn1	ER-MT; MT-ER	Mouse	more

Expression Overview of Sel1l:

Homology Information of Sel1l:

Uniprot ID	Q9Z2G6
EggNOG	KOG1550
HOGENOM	CLU_007931_2_1_1
OrthoDB	1378605at2759
TreeFam	TF315257
GeneTree	ENSGT00940000156671

References:

Pubmed ID	32193362
DOI	10.1126/science.aay2494
Description	Sel1L-Hrd1 ERAD regulates MAM and Mitochondrionl dynamics via SigmaR1.
Description of experimental evidence	The protein was validated by western blot, histology, immunofluorescence, confocal microscopy, TEM, SBF-SEM, FIB-SEM, immunogold labeling, microarray analysis, RT-PCR, qPCR and IP in brown adipocytes, and this study may have implications not only for interorganelle communication, but also for the pathophysiological role of Sel1L-Hrd1 ERAD.
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Pubmed ID	29785746
DOI	10.1002/pmic.201700478
Description	By Andromeda search engine against the decoy UniProt-mouse database and Swiss-Prot human database, which yielded 2,808 proteins from mouse testes (mT),2,478 proteins from mouse brain (mB) and 2,155 proteins from human testes (hT).
Description of experimental evidence	The protein was validated by TEM and LC -MS/MS analyses in mouse testes and mouse brains.
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