Basic Information:

Symbol	Sec22b
Synonyms	Sec22l1
Species	Mouse
Entrez ID	20333
Uniprot ID	O08547
Membrane Contact Site	ER-PM; PM-ER
Location (from literature)	ER
Cell line/Tissue	MEFs
Experimental Method	Low throughput experimental methods
Protein Sequence

Complex Information:

Complex ID	Subunit of complex	Subcellular location	Species	More
CMCS00153	Sec22b; Stim1	ER-PM; PM-ER	Mouse	more

Expression Overview of Sec22b:

Homology Information of Sec22b:

Uniprot ID	O08547
EggNOG	KOG0862
HOGENOM	CLU_054453_4_1_1
OrthoDB	129635at2759
TreeFam	TF105933
GeneTree	ENSGT00940000156349

References:

DOI	https://doi.org/10.1101/2022.04.12.487993
Description	Total internal reflection microscopy (TIRF) analysis allowed simultaneous imaging of Sec22b and STIM1 recruitment to ER-PM MCS, visible as puncta at the PM plane, during the activation of store-operated Ca2+ entry (SOCE) .
Description of experimental evidence	The protein was validated by immunofluorescence , EM, CLEM, calcium imaging , TIRF imaging , PLF assay, immunoblotting, immunoprecipitation and flow cytometry in MEFs.
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