Basic Information:

Symbol	STARD3NL
Synonyms	MENTHO; UNQ855/PRO1864
Protein Name	STARD3 N-terminal-like protein (MLN64 N-terminal domain homolog)
Species	Human
Entrez ID	83930
Uniprot ID	O95772
Membrane Contact Site	ER-Endosome; Endosome-ER
Location (from literature)	Endosome
Cell line/Tissue	HeLa cells; HEK293T cells
Experimental Method	Low throughput experimental methods
Protein Sequence
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Complex Information:

Complex ID	Subunit of complex	Subcellular location	Species	More
CMCS00013	MOSPD2; STARD3NL	ER-Endosome; Endosome-ER	Human	more
CMCS00024	VAPA; VAPB; STARD3NL	ER-Endosome; Endosome-ER	Human	more

Expression Overview of STARD3NL:

Homology Information of STARD3NL:

Uniprot ID	O95772
EggNOG	KOG3845
HOGENOM	/
OrthoDB	3740290at2759
TreeFam	TF313869
GeneTree	ENSGT00940000155476

References:

Pubmed ID	24105263
DOI	10.1242/jcs.139295
Description	STARD3 or STARD3NL and VAP form a novel molecular tether between late endosomes and the ER.
Description of experimental evidence	The protein was validated by immunoprecipitation, electron microscopy, immunofluorescence, in situ proximity ligation assay, mSDS-PAGE and western blot analysis in HeLa cells.
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Pubmed ID	29858488
DOI	10.15252/embr.201745453
Description	Consequently, MOSPD2 and these organelle‐bound proteins mediate the formation of contact sites between the ER and endosomes, mitochondria, or Golgi.; ll these proteins, by binding VAP proteins, are known to build contact sites between the ER and endosomes (STARD3, STARD3NL, ORP1L), mitochondria (PTPIP51), and Golgi (STARD11).
Description of experimental evidence	The protein was validated by immunofluorescence, colocalization analysis, SDS–PAGE, western blot, coomassie blue staining, pull‐down assays, GFP‐Trap, mass spectrometry analysis, electron microscopy and immunoprecipitation in HeLa cells and HEK293T cells.
More related results