ID	检索号	作者	基因	基因ID	正义链	反义链	5.end	3.end	Sec.dG	Hsieh	Amarzguioui	GC stretch	Whole ∆G	Katoh	Takasaki	Reynolds	Ui-Tei	%GC	i-score	%抑制效率	实验技术	细胞	浓度	时间	文献标题	PMID	发表年份	发表杂志	发表日期
MC0001	NM_012249	Huesken	TC10	23433	CUAAUAUGUUAAUUGAUUUau	AAAUCAAUUAACAUAUUAG	-0.9	-2.1	2.1	0	-1	1	-24.6	95.4	-1.3	6	II	15.8	57	46.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0002	NM_012249	Huesken	TC10	23433	AAUAUGUUAAUUGAUUUAUac	AUAAAUCAAUUAACAUAUU	-1.1	-0.9	2.5	2	1	1	-23.6	104.2	-1	9	II	10.5	65.3	38.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0003	NM_012249	Huesken	TC10	23433	GAUUUAUACAAUUCCUUUCaa	GAAAGGAAUUGUAUAAAUC	-2.4	-2.4	2.3	2	1	2	-28.2	102.6	12.7	7	II	26.3	61.5	51.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0004	NM_012249	Huesken	TC10	23433	CAAUUCCUUUCAAUUUUAUcu	AUAAAAUUGAAAGGAAUUG	-1.1	-2.1	1.3	-1	-1	2	-26.2	87.4	-8.6	5	II	21.1	44.5	36.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0005	NM_012249	Huesken	TC10	23433	CAGACCAAAAUUAAAUAAGaa	CUUAUUUAAUUUUGGUCUG	-2.1	-2.1	2.8	-1	-1	2	-27.4	79.6	-1.6	4	II	26.3	56.4	52.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0006	NM_012249	Huesken	TC10	23433	AGACCAAAAUUAAAUAAGAaa	UCUUAUUUAAUUUUGGUCU	-2.4	-2.1	2.8	2	0	2	-27.7	65.6	-6.3	4	II	21.1	51.3	44.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0007	NM_012249	Huesken	TC10	23433	ACCAAAAUUAAAUAAGAAAgu	UUUCUUAUUUAAUUUUGGU	-0.9	-2.2	2.8	1	-2	2	-25	79.6	1.3	6	II	15.8	48.6	44.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0008	NM_012249	Huesken	TC10	23433	CAAAAUUAAAUAAGAAAGUua	ACUUUCUUAUUUAAUUUUG	-2.2	-2.1	3.7	-1	-1	1	-23.8	77.8	-5.9	6	II	15.8	59.3	43.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0009	NM_012249	Huesken	TC10	23433	UAAGAAAGUUACAUAAGAUuc	AUCUUAUGUAACUUUCUUA	-1.1	-1.3	3.5	0	3	1	-28.2	78.1	-1.6	7	II	21.1	64.2	59.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0010	NM_012249	Huesken	TC10	23433	AAGUUACAUAAGAUUCCAUuu	AUGGAAUCUUAUGUAACUU	-1.1	-0.9	2.3	1	2	2	-30.4	81.9	-1.9	6	II	26.3	54.2	51.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0011	NM_012249	Huesken	TC10	23433	ACAUAAGAUUCCAUUUGAGca	CUCAAAUGGAAUCUUAUGU	-2.1	-2.2	1.4	1	4	2	-31.4	68.1	-2.3	6	Ia	31.6	52	55.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0012	NM_012249	Huesken	TC10	23433	AAGAUUCCAUUUGAGCAUAca	UAUGCUCAAAUGGAAUCUU	-1.3	-0.9	1.4	1	-1	2	-32.6	71.6	-0.7	5	II	31.6	50.8	54.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0013	NM_012249	Huesken	TC10	23433	CCAUUUGAGCAUACAUAAGgc	CUUAUGUAUGCUCAAAUGG	-2.1	-3.3	1.2	0	-1	2	-32.5	69	0.7	4	II	36.8	46	44	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0014	NM_012249	Huesken	TC10	23433	CAUUUGAGCAUACAUAAGGcc	CCUUAUGUAUGCUCAAAUG	-3.3	-2.1	1.2	0	1	2	-32.5	74.1	0.4	6	II	36.8	63.2	65.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0015	NM_012249	Huesken	TC10	23433	AUAAGGCCAUGAUACUUUAau	UAAAGUAUCAUGGCCUUAU	-1.3	-1.1	1.3	1	0	4	-32.9	70.1	-3.8	6	II	31.6	51.7	75.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0016	NM_012249	Huesken	TC10	23433	GCCAUGAUACUUUAAUGUGaa	CACAUUAAAGUAUCAUGGC	-2.1	-3.4	1.2	0	0	3	-32.6	69	3	3	II	36.8	45.2	62.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0017	NM_012249	Huesken	TC10	23433	UUAAUGUGAACCACCAUUUcu	AAAUGGUGGUUCACAUUAA	-0.9	-0.9	-2.4	1	1	2	-32	85.4	-11.3	9	II	31.6	76.4	85.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0018	NM_012249	Huesken	TC10	23433	UGUGAACCACCAUUUCUUGga	CAAGAAAUGGUGGUUCACA	-2.1	-2.1	-0.3	0	3	2	-35.3	70.6	2.7	6	Ib	42.1	58.9	84.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0019	NM_012249	Huesken	TC10	23433	GAACCACCAUUUCUUGGAAga	UUCCAAGAAAUGGUGGUUC	-0.9	-2.4	-0.8	1	0	2	-35.5	58.4	4	2	III	42.1	27	38.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0020	NM_012249	Huesken	TC10	23433	AUUUCUUGGAAGAAAGAAGac	CUUCUUUCUUCCAAGAAAU	-2.1	-1.1	-1.4	3	3	2	-30.8	85.3	-0.3	6	Ia	31.6	66.7	53.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0021	NM_012249	Huesken	TC10	23433	UGGAAGAAAGAAGACAUCCaa	GGAUGUCUUCUUUCUUCCA	-3.3	-2.1	-1.8	0	2	2	-36	64.9	12.4	6	Ib	42.1	74.2	83.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0022	NM_012249	Huesken	TC10	23433	GGAAGAAAGAAGACAUCCAaa	UGGAUGUCUUCUUUCUUCC	-2.1	-3.3	-0.1	1	-1	2	-36	50.5	-4	4	II	42.1	40.7	68.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0023	NM_012249	Huesken	TC10	23433	GAAAGAAGACAUCCAAAUGuc	CAUUUGGAUGUCUUCUUUC	-2.1	-2.4	0.2	0	1	2	-32.3	66.7	7.7	4	II	36.8	50.6	73.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0024	NM_012249	Huesken	TC10	23433	AAGACAUCCAAAUGUCCGAuu	UCGGACAUUUGGAUGUCUU	-2.4	-0.9	-4.7	2	1	3	-36.3	68.9	-1.5	5	II	42.1	53.8	83	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0025	NM_012249	Huesken	TC10	23433	CAUCCAAAUGUCCGAUUCAga	UGAAUCGGACAUUUGGAUG	-2.1	-2.1	0.8	-1	-2	3	-35.2	54.7	-5.7	4	II	42.1	41.2	38.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0026	NM_012249	Huesken	TC10	23433	UUCCUGGCCAGUCAUCCAGua	CUGGAUGACUGGCCAGGAA	-2.1	-0.9	-4.5	2	3	4	-42.7	63.9	5.4	5	II	57.9	65.3	75.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0027	NM_012249	Huesken	TC10	23433	CCUGGCCAGUCAUCCAGUAga	UACUGGAUGACUGGCCAGG	-1.3	-3.3	-5	0	-3	4	-42.9	34.8	-8.1	-1	III	57.9	25.2	55.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0028	NM_012249	Huesken	TC10	23433	AGUCAUCCAGUAGACUCUCuc	GAGAGUCUACUGGAUGACU	-2.4	-2.1	-3	2	3	2	-39	52.8	10.1	3	Ib	47.4	55.6	77.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0029	NM_012249	Huesken	TC10	23433	AGACUCUCUCCACUCUUCAau	UGAAGAGUGGAGAGAGUCU	-2.1	-2.1	1.2	3	1	2	-39.8	66	-1.4	6	II	47.4	52.6	70.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0030	NM_012249	Huesken	TC10	23433	GGAAGGUGAUGCUUAUAUUuu	AAUAUAAGCAUCACCUUCC	-0.9	-3.3	1.9	1	-1	2	-34	66.1	-4	3	III	36.8	38	51.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0031	NM_012249	Huesken	TC10	23433	UCUACAAAGCUCACAUACAac	UGUAUGUGAGCUUUGUAGA	-2.1	-2.4	1.2	1	0	2	-35	65.7	-8.7	6	II	36.8	57.8	75.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0032	NM_012249	Huesken	TC10	23433	CAACAAGACAGUACAUCCUag	AGGAUGUACUGUCUUGUUG	-2.1	-2.1	-1.8	1	0	2	-35.8	58.6	-2.8	4	II	42.1	51.4	81.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0033	NM_012249	Huesken	TC10	23433	ACAGUACAUCCUAGAUUUGug	CAAAUCUAGGAUGUACUGU	-2.1	-2.2	-0.3	0	2	2	-33.9	58.5	-1.9	5	Ib	36.8	49.5	79.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0034	NM_012249	Huesken	TC10	23433	UCCUAGAUUUGUGACUGAUau	AUCAGUCACAAAUCUAGGA	-1.1	-2.4	1.5	0	0	2	-35.2	69.7	1.8	6	II	36.8	50.2	75.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0035	NM_012249	Huesken	TC10	23433	UUUGUGACUGAUAUGAGCAuu	UGCUCAUAUCAGUCACAAA	-2.1	-0.9	0.9	0	3	2	-35	81.4	1.3	7	II	36.8	71.6	83.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0036	NM_012249	Huesken	TC10	23433	UGUGACUGAUAUGAGCAUUua	AAUGCUCAUAUCAGUCACA	-0.9	-2.1	0.9	1	0	2	-35.2	71.3	4.1	6	II	36.8	56	76	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0037	NM_012249	Huesken	TC10	23433	GCAUUUAAGGCUGUCAUUUuc	AAAUGACAGCCUUAAAUGC	-0.9	-3.4	1.5	1	-1	3	-33.2	70.1	-1	5	II	36.8	44.3	42.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0038	NM_012249	Huesken	TC10	23433	UUUAAGGCUGUCAUUUUCAag	UGAAAAUGACAGCCUUAAA	-2.1	-0.9	2.4	0	2	3	-32	81.7	-3.7	9	II	31.6	71.2	78.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0039	NM_012249	Huesken	TC10	23433	UUAAGGCUGUCAUUUUCAAgu	UUGAAAAUGACAGCCUUAA	-0.9	-0.9	2.1	1	2	3	-32	76.1	-3.8	6	II	31.6	55.5	87.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0040	NM_012249	Huesken	TC10	23433	AAGUAUAAAAGUUUAGUGUuc	ACACUAAACUUUUAUACUU	-2.2	-0.9	2.9	1	2	1	-27.6	99.4	4.1	8	II	21.1	65.3	76.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0041	NM_012249	Huesken	TC10	23433	UAAAAGUUUAGUGUUCCAUua	AUGGAACACUAAACUUUUA	-1.1	-1.3	0.8	1	3	2	-29.8	92.4	4.1	9	II	26.3	70.5	82.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0042	NM_012249	Huesken	TC10	23433	GUGUUCCAUUACCCAAUCUgu	AGAUUGGGUAAUGGAACAC	-2.1	-2.2	1	0	-1	3	-35.9	69.2	-1.6	4	III	42.1	43.2	72	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0043	NM_012249	Huesken	TC10	23433	UGUUCCAUUACCCAAUCUGug	CAGAUUGGGUAAUGGAACA	-2.1	-2.1	1	0	3	3	-35.8	80.3	-2.3	7	Ib	42.1	67.6	86.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0044	NM_012249	Huesken	TC10	23433	GUUCCAUUACCCAAUCUGUgc	ACAGAUUGGGUAAUGGAAC	-2.2	-2.2	1.5	2	0	3	-35.9	65.3	-11.3	4	II	42.1	45.1	47.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0045	NM_012249	Huesken	TC10	23433	UGUGCAGUAGACAUAGCUAua	UAGCUAUGUCUACUGCACA	-1.3	-2.1	-0.8	0	1	2	-37.6	63.8	-4.1	5	II	42.1	52	86.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0046	NM_012249	Huesken	TC10	23433	UGCAGUAGACAUAGCUAUAag	UAUAGCUAUGUCUACUGCA	-1.3	-2.1	-0.8	-1	-2	2	-35.7	67.8	-1	5	II	36.8	50.5	77.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0047	NM_012249	Huesken	TC10	23433	UAGCUAUAAGCUCAAGUCAug	UGACUUGAGCUUAUAGCUA	-2.1	-1.3	-2.2	2	0	2	-35.3	73.6	-0.7	6	II	36.8	62.6	84.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0048	NM_012249	Huesken	TC10	23433	AUAAGCUCAAGUCAUGUGAau	UCACAUGACUUGAGCUUAU	-2.4	-1.1	0.8	2	1	2	-35	80.5	1.7	8	II	36.8	59.9	87	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0049	NM_012249	Huesken	TC10	23433	CUCAAGUCAUGUGAAUUAAca	UUAAUUCACAUGACUUGAG	-0.9	-2.1	0.7	0	-4	1	-31.3	69.2	0	5	II	31.6	37.5	54.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0050	NM_012249	Huesken	TC10	23433	UAUAAUUUGGGCAACAGCAag	UGCUGUUGCCCAAAUUAUA	-2.1	-1.3	-0.6	2	2	4	-34.5	79.6	-6	8	II	36.8	72.2	85.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0051	NM_012249	Huesken	TC10	23433	AUAAUUUGGGCAACAGCAAgu	UUGCUGUUGCCCAAAUUAU	-0.9	-1.1	-0.6	3	1	4	-34.1	65	-8.7	7	II	36.8	56	83.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0052	NM_012249	Huesken	TC10	23433	GCAACAGCAAGUUUAAAUGua	CAUUUAAACUUGCUGUUGC	-2.1	-3.4	0	0	1	2	-31.6	74.9	5.4	4	II	36.8	47.8	74.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0053	NM_012249	Huesken	TC10	23433	ACAGCAAGUUUAAAUGUAGga	CUACAUUUAAACUUGCUGU	-2.1	-2.2	1.5	1	2	2	-30.8	61.6	-2.6	5	Ib	31.6	55.4	82.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0054	NM_012249	Huesken	TC10	23433	AUUGUUUCUCUAAAAUGCAuu	UGCAUUUUAGAGAAACAAU	-2.1	-1.1	2.2	2	2	2	-29.8	77.4	-6.3	6	II	26.3	65.2	84.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0055	NM_012249	Huesken	TC10	23433	AUGCAUUAGGUUGUUCACAau	UGUGAACAACCUAAUGCAU	-2.1	-1.1	-0.2	4	1	2	-34.5	69.7	4.3	5	II	36.8	59.7	75.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0056	NM_012249	Huesken	TC10	23433	UGCAUUAGGUUGUUCACAAug	UUGUGAACAACCUAAUGCA	-0.9	-2.1	-0.8	1	0	2	-34.3	76.2	-1.4	6	II	36.8	54.5	83	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0057	NM_012249	Huesken	TC10	23433	UAACACCAUUAUCUGAUGCau	GCAUCAGAUAAUGGUGUUA	-3.4	-1.3	-4.7	1	5	2	-34.1	85.5	20.2	6	Ib	36.8	71.6	92.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0058	NM_012249	Huesken	TC10	23433	AACACCAUUAUCUGAUGCAuc	UGCAUCAGAUAAUGGUGUU	-2.1	-0.9	-4.9	0	1	2	-34.9	74	-6.1	5	II	36.8	55.2	61.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0059	NM_012249	Huesken	TC10	23433	CAUUAUCUGAUGCAUCCAUua	AUGGAUGCAUCAGAUAAUG	-1.1	-2.1	1.2	0	-1	2	-34.2	70.3	-0.9	5	II	36.8	44.9	82.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0060	NM_012249	Huesken	TC10	23433	UAUCUGAUGCAUCCAUUAUcu	AUAAUGGAUGCAUCAGAUA	-1.1	-1.3	1.1	2	1	2	-33.4	87	3.8	8	II	31.6	61.3	80.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0061	NM_012249	Huesken	TC10	23433	CUGAUGCAUCCAUUAUCUGau	CAGAUAAUGGAUGCAUCAG	-2.1	-2.1	0.7	-1	1	2	-35.2	65.1	-2	3	II	42.1	51.3	80.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0062	NM_012249	Huesken	TC10	23433	AUCCAUUAUCUGAUGCAUGgc	CAUGCAUCAGAUAAUGGAU	-2.1	-1.1	0.3	3	3	2	-34.2	73.3	2.4	5	Ia	36.8	66.5	72.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0063	NM_012249	Huesken	TC10	23433	CAUUAUCUGAUGCAUGGCAua	UGCCAUGCAUCAGAUAAUG	-2.1	-2.1	0.1	0	-1	3	-36.2	65.8	-0.7	5	II	42.1	45.8	59.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0064	NM_012249	Huesken	TC10	23433	UUAUCUGAUGCAUGGCAUAug	UAUGCCAUGCAUCAGAUAA	-1.3	-0.9	-0.7	-1	0	3	-35.4	70.9	-6.1	7	II	36.8	59.7	75.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0065	NM_012249	Huesken	TC10	23433	AUGCAAUAAGGCAGAUCCAca	UGGAUCUGCCUUAUUGCAU	-2.1	-1.1	-1.1	2	1	3	-37.2	51.8	-6	4	II	42.1	50.4	88.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0066	NM_012249	Huesken	TC10	23433	GCAAUAAGGCAGAUCCACAgc	UGUGGAUCUGCCUUAUUGC	-2.1	-3.4	-0.2	1	-1	3	-38.3	50.9	-1.7	4	II	47.4	39.8	68.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0067	NM_012249	Huesken	TC10	23433	CAAUAAGGCAGAUCCACAGca	CUGUGGAUCUGCCUUAUUG	-2.1	-2.1	-0.2	0	1	3	-37	61	0.7	6	II	47.4	52.8	79	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0068	NM_004359	Huesken	CDC34	997	CGUCCCGUAGUAGUCGUCGua	CGACGACUACUACGGGACG	-2.4	-2.4	0.6	0	1	4	-41.2	47.7	0.3	2	II	63.2	47	62.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0069	NM_004359	Huesken	CDC34	997	CCCGUAGUAGUCGUCGUAGaa	CUACGACGACUACUACGGG	-2.1	-3.3	0.6	-1	-1	4	-39.8	44.2	-2	2	II	57.9	38.2	69	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0070	NM_004359	Huesken	CDC34	997	GUAGUCGUCGUAGAAGAGGuc	CCUCUUCUACGACGACUAC	-3.3	-2.2	1.4	1	2	2	-38.4	46	0	4	II	52.6	53	82.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0071	NM_004359	Huesken	CDC34	997	UAGUCGUCGUAGAAGAGGUcu	ACCUCUUCUACGACGACUA	-2.2	-1.3	1.4	2	2	2	-38.4	67.7	-4.3	6	II	47.4	62.9	89.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0072	NM_004359	Huesken	CDC34	997	GUCGUAGAAGAGGUCUGAGcc	CUCAGACCUCUUCUACGAC	-2.1	-2.2	0.4	0	2	2	-39.1	50	4.6	3	II	52.6	39.7	37.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0073	NM_004359	Huesken	CDC34	997	AGAGGUCUGAGCCCUCGUCgg	GACGAGGGCUCAGACCUCU	-2.4	-2.1	-5.8	2	3	4	-44.7	48.9	7.5	2	II	63.2	53	51.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0074	NM_004359	Huesken	CDC34	997	GUCUGAGCCCUCGUCGGGCgc	GCCCGACGAGGGCUCAGAC	-3.4	-2.2	-7.8	1	3	5	-47.2	35.3	7.4	1	II	73.7	43.3	33.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0075	NM_004359	Huesken	CDC34	997	GUCGGGCGCCGGCGCCUUGgu	CAAGGCGCCGGCGCCCGAC	-2.1	-2.2	-6.9	0	0	14	-49.4	18.3	2.4	0	II	84.2	30.7	26.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0076	NM_004359	Huesken	CDC34	997	GCGCCGGCGCCUUGGUCUUca	AAGACCAAGGCGCCGGCGC	-0.9	-3.4	-2.6	1	-2	11	-46.7	25.6	-3.3	-1	III	73.7	21.7	25.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0077	NM_004359	Huesken	CDC34	997	UGGUCUUCACGCAGUACUCgg	GAGUACUGCGUGAAGACCA	-2.4	-2.1	0.3	0	2	3	-39.9	68.2	2.5	5	Ib	52.6	62.3	73.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0078	NM_004359	Huesken	CDC34	997	GUCUUCACGCAGUACUCGGcc	CCGAGUACUGCGUGAAGAC	-3.3	-2.2	0.3	1	2	3	-40.2	61.4	2.3	3	II	57.9	49.6	59	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0079	NM_004359	Huesken	CDC34	997	UUCACGCAGUACUCGGCCAgc	UGGCCGAGUACUGCGUGAA	-2.1	-0.9	-0.3	1	1	5	-42.3	58.9	-3.8	4	II	57.9	54.1	65.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0080	NM_004359	Huesken	CDC34	997	CGCAGUACUCGGCCAGCGUgg	ACGCUGGCCGAGUACUGCG	-2.2	-2.4	-1.6	-1	-2	5	-44.8	37.9	-3.6	0	III	68.4	34.3	52.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0081	NM_004359	Huesken	CDC34	997	GUCACGCUCCGCGUCCACCuu	GGUGGACGCGGAGCGUGAC	-3.3	-2.2	-2.9	1	2	5	-46.2	45.4	7.4	0	II	73.7	46.3	53.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0082	NM_004359	Huesken	CDC34	997	CCUUGGUCCCCAGGACCUGcu	CAGGUCCUGGGGACCAAGG	-2.1	-3.3	-7.4	0	0	4	-45.8	28.9	-4.4	1	II	68.4	37.3	43	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0083	NM_004359	Huesken	CDC34	997	GUCCCCAGGACCUGCUUCCgg	GGAAGCAGGUCCUGGGGAC	-3.3	-2.2	-2.2	1	1	4	-46.2	48.2	2.7	2	II	68.4	47.5	58.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0084	NM_004359	Huesken	CDC34	997	GCUUCCGGAUGAUGUCUGUgu	ACAGACAUCAUCCGGAAGC	-2.2	-3.4	1.2	-1	-1	4	-40	52.9	-4	4	III	52.6	27.2	34.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0085	NM_004359	Huesken	CDC34	997	GAUGAUGUCUGUGUACUCCcg	GGAGUACACAGACAUCAUC	-3.3	-2.4	0.7	1	3	2	-37.8	69.5	15.5	5	II	47.4	55.1	76.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0086	NM_004359	Huesken	CDC34	997	UGUGUACUCCCGAUCCUUCcc	GAAGGAUCGGGAGUACACA	-2.4	-2.1	1.2	1	3	4	-40.2	66.1	4.8	6	Ib	52.6	62.6	74.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0087	NM_004359	Huesken	CDC34	997	GUGUACUCCCGAUCCUUCCcc	GGAAGGAUCGGGAGUACAC	-3.3	-2.2	1.2	2	1	4	-41.4	67.7	10.1	4	II	57.9	55.5	56.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0088	NM_004359	Huesken	CDC34	997	CCCGAUCCUUCCCCUUGCUcu	AGCAAGGGGAAGGAUCGGG	-2.1	-3.3	-0.9	-1	-2	4	-44.1	39.7	-5.6	0	III	63.2	30.7	41.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0089	NM_004359	Huesken	CDC34	997	UUUCCACUUCCUGUACAUCac	GAUGUACAGGAAGUGGAAA	-2.4	-0.9	0.4	1	4	2	-36	75.1	10.4	5	Ib	42.1	64.9	82.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0090	NM_004359	Huesken	CDC34	997	CCUGUACAUCACGGAGGCGuc	CGCCUCCGUGAUGUACAGG	-2.4	-3.3	-0.3	-2	1	4	-42.4	31	-2.1	1	II	63.2	35.3	36.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0091	NM_004359	Huesken	CDC34	997	CAUCACGGAGGCGUCCACGuu	CGUGGACGCCUCCGUGAUG	-2.4	-2.1	-2.9	0	2	4	-43.8	41.4	0.7	2	II	68.4	49.6	79.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0092	NM_004359	Huesken	CDC34	997	UCACGGAGGCGUCCACGUUug	AACGUGGACGCCUCCGUGA	-0.9	-2.4	-3.4	2	1	4	-43.7	38.9	1.5	3	II	63.2	48.6	55.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0093	NM_004359	Huesken	CDC34	997	CGGGCGAGAAGGUGUUGGGcu	CCCAACACCUUCUCGCCCG	-3.3	-2.4	4.6	-2	0	6	-44.1	37.9	-2	1	II	68.4	37.9	45.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0094	NM_004359	Huesken	CDC34	997	GUUGGGCUCGUUCAGGAGGga	CCUCCUGAACGAGCCCAAC	-3.3	-2.2	-0.7	1	2	4	-42.9	45	5.4	1	II	63.2	46.9	68.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0095	NM_004359	Huesken	CDC34	997	UCGUUCAGGAGGGAGAUCAca	UGAUCUCCCUCCUGAACGA	-2.1	-2.4	0.6	1	-1	3	-41.4	59.7	-3.8	8	II	52.6	56.7	70	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0096	NM_004359	Huesken	CDC34	997	GGAGGGAGAUCACACUCAGga	CUGAGUGUGAUCUCCCUCC	-2.1	-3.3	-1.4	0	1	3	-42.1	33.2	0.1	0	II	57.9	37.1	23.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0097	NM_004359	Huesken	CDC34	997	GAGGGAGAUCACACUCAGGag	CCUGAGUGUGAUCUCCCUC	-3.3	-2.4	-1.4	0	1	3	-42.1	40.2	-2.6	0	II	57.9	44.9	58.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0098	NM_004359	Huesken	CDC34	997	GGGAGAUCACACUCAGGAGaa	CUCCUGAGUGUGAUCUCCC	-2.1	-3.3	-1.4	1	0	3	-42.1	48.2	-0.1	0	II	57.9	34.7	42.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0099	NM_004359	Huesken	CDC34	997	UCACACUCAGGAGAAUGGUcc	ACCAUUCUCCUGAGUGUGA	-2.2	-2.4	-3.8	2	2	2	-39.5	52.6	-1.3	5	II	47.4	55.2	81.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0100	NM_004359	Huesken	CDC34	997	CACACUCAGGAGAAUGGUCcu	GACCAUUCUCCUGAGUGUG	-2.4	-2.1	-3.8	0	0	2	-39.5	55.8	5.1	1	II	52.6	47.3	44.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0101	NM_004359	Huesken	CDC34	997	CAGGAGAAUGGUCCUGACGuu	CGUCAGGACCAUUCUCCUG	-2.4	-2.1	-4.8	-1	0	2	-40.9	51.1	6.1	1	II	57.9	53.3	72.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0102	NM_004359	Huesken	CDC34	997	AGGAGAAUGGUCCUGACGUuc	ACGUCAGGACCAUUCUCCU	-2.2	-2.1	-2.4	2	2	2	-41	52.4	-1.6	3	II	52.6	51.6	72.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0103	NM_004359	Huesken	CDC34	997	CUGACGUUCUGCGUGGGGUuc	ACCCCACGCAGAACGUCAG	-2.2	-2.1	0	1	0	4	-43.1	52.4	-6	2	III	63.2	43	57.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0104	NM_004359	Huesken	CDC34	997	UCUGCGUGGGGUUCCACCUcu	AGGUGGAACCCCACGCAGA	-2.1	-2.4	-5.2	2	2	4	-45.1	58.4	-1	3	II	63.2	60	72.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0105	NM_004359	Huesken	CDC34	997	CCACCUCUCUGAGGGCAGCuc	GCUGCCCUCAGAGAGGUGG	-3.4	-3.3	-3.2	0	0	4	-46.2	33.2	5.4	-1	II	68.4	36.1	39.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0106	NM_004359	Huesken	CDC34	997	GGUCGUCCACCGGCGGGUGga	CACCCGCCGGUGGACGACC	-2.1	-3.3	-4.2	1	1	8	-48.2	23.4	-2.4	-1	II	78.9	27.8	25.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0107	NM_004359	Huesken	CDC34	997	GUCGUCCACCGGCGGGUGGag	CCACCCGCCGGUGGACGAC	-3.3	-2.2	-7.3	0	1	8	-48.2	32.5	2.4	1	II	78.9	33.5	44.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0108	NM_004359	Huesken	CDC34	997	CGUAGAUGUUAGGGUGCCAca	UGGCACCCUAACAUCUACG	-2.1	-2.4	1.2	-1	-2	3	-39.8	42.1	-3.5	3	II	52.6	31.1	25.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0109	NM_004359	Huesken	CDC34	997	UGUUAGGGUGCCACAUCUUgg	AAGAUGUGGCACCCUAACA	-0.9	-2.1	0.9	0	1	3	-39.1	56.3	-8.6	7	II	47.4	55.3	36.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0110	NM_004359	Huesken	CDC34	997	GUGGAGAGUAUGGGUAGUCga	GACUACCCAUACUCUCCAC	-2.4	-2.2	2.7	-1	1	3	-40.1	40.6	10.1	4	II	52.6	48.3	65.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0111	NM_004359	Huesken	CDC34	997	GUAUGGGUAGUCGAUGGGGaa	CCCCAUCGACUACCCAUAC	-3.3	-2.2	4.1	0	3	4	-41.4	42.3	-2.4	3	II	57.9	49.2	44.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0112	NM_004359	Huesken	CDC34	997	GAUGGGGAACUUGAGGCGCgc	GCGCCUCAAGUUCCCCAUC	-3.4	-2.4	1.6	0	3	5	-43.1	36.5	10.4	2	II	63.2	47.2	58	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0113	NM_004359	Huesken	CDC34	997	AUGGGGAACUUGAGGCGCGcc	CGCGCCUCAAGUUCCCCAU	-2.4	-1.1	1.3	1	4	6	-43.1	34.7	-2.6	3	II	63.2	59.3	51.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0114	NM_004359	Huesken	CDC34	997	CGCCUUGAAGUAGCCGCCCuc	GGGCGGCUACUUCAAGGCG	-3.3	-2.4	-1.8	0	0	7	-44.3	34.4	5.4	0	II	68.4	47.1	29.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0115	NM_004359	Huesken	CDC34	997	GAAGUAGCCGCCCUCGUAGua	CUACGAGGGCGGCUACUUC	-2.1	-2.4	-1.9	1	2	7	-42.6	47.6	0	3	II	63.2	45.1	59.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0116	NM_004359	Huesken	CDC34	997	AAGUAGCCGCCCUCGUAGUag	ACUACGAGGGCGGCUACUU	-2.2	-0.9	0	2	1	7	-42.4	52.7	-6	4	II	57.9	47.2	73.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0117	NM_004359	Huesken	CDC34	997	CCUCCCAGUUGUAUAGAUCgc	GAUCUAUACAACUGGGAGG	-2.4	-3.3	-0.1	0	0	3	-37.7	62.4	8.2	2	II	47.4	44.2	41.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0118	NM_004359	Huesken	CDC34	997	UCCCAGUUGUAUAGAUCGCcc	GCGAUCUAUACAACUGGGA	-3.4	-2.4	-0.1	2	3	3	-38.1	60.7	12.8	5	II	47.4	59.4	74	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0119	NM_004359	Huesken	CDC34	997	GUUGUAUAGAUCGCCCUCGuc	CGAGGGCGAUCUAUACAAC	-2.4	-2.2	-0.1	2	2	5	-38.4	58.2	-2.4	6	II	52.6	58.7	72.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0120	NM_004359	Huesken	CDC34	997	UGUAUAGAUCGCCCUCGUCca	GACGAGGGCGAUCUAUACA	-2.4	-2.1	-0.1	0	3	5	-39.9	64.6	7.5	7	Ia	52.6	61.2	64.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0121	NM_004359	Huesken	CDC34	997	UCGCCCUCGUCCACCAGUGuc	CACUGGUGGACGAGGGCGA	-2.1	-2.4	0.3	3	2	5	-45.7	46.1	-7.3	3	II	68.4	56.7	75.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0122	NM_004359	Huesken	CDC34	997	CGUCCACCAGUGUCACGCGga	CGCGUGACACUGGUGGACG	-2.4	-2.4	-0.4	0	1	4	-43.5	37.9	-2	0	II	68.4	38.9	67.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0123	NM_004359	Huesken	CDC34	997	CCCUCGACCGGCUCUUCCUgc	AGGAAGAGCCGGUCGAGGG	-2.1	-3.3	-1.6	0	-2	5	-45.8	48	-8.3	0	III	68.4	37.7	44.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0124	NM_004359	Huesken	CDC34	997	CGGCUCUUCCUGCAGCCCCuu	GGGGCUGCAGGAAGAGCCG	-3.3	-2.4	-5.6	2	0	5	-47.4	41.9	7.8	0	II	73.7	49.5	47.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0125	NM_003340	Huesken	UBE2D3	7323	GUCUGUUUUAUAGAUCCGUgc	ACGGAUCUAUAAAACAGAC	-2.2	-2.2	0.8	1	0	3	-33.3	68.4	-4	4	II	36.8	51.4	68.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0126	NM_003340	Huesken	UBE2D3	7323	UUUAUAGAUCCGUGCAAUCuc	GAUUGCACGGAUCUAUAAA	-2.4	-0.9	-0.7	-1	3	3	-33.4	77.6	5.1	8	Ia	36.8	71.1	92.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0127	NM_003340	Huesken	UBE2D3	7323	AGAUCCGUGCAAUCUCUGGca	CCAGAGAUUGCACGGAUCU	-3.3	-2.1	-1.5	2	3	3	-39.9	67.4	2.3	5	II	52.6	56.3	82	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0128	NM_003340	Huesken	UBE2D3	7323	CGUGCAAUCUCUGGCACUAgg	UAGUGCCAGAGAUUGCACG	-1.3	-2.4	-4.8	-1	-3	3	-39.7	43.5	-5.1	1	III	52.6	29.4	62.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0129	NM_003340	Huesken	UBE2D3	7323	UGCAAUCUCUGGCACUAGGgg	CCUAGUGCCAGAGAUUGCA	-3.3	-2.1	-0.4	1	2	3	-40.5	66.3	5.1	5	Ib	52.6	59.2	86.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0130	NM_003340	Huesken	UBE2D3	7323	GGGUCAUCUGGGUUUGGAUca	AUCCAAACCCAGAUGACCC	-1.1	-3.3	0.9	1	-1	3	-40.5	60.4	-1.6	2	III	52.6	28.8	44.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0131	NM_003340	Huesken	UBE2D3	7323	GGUCAUCUGGGUUUGGAUCac	GAUCCAAACCCAGAUGACC	-2.4	-3.3	0.5	2	1	3	-39.6	64.6	15.5	2	II	52.6	41.2	56.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0132	NM_003340	Huesken	UBE2D3	7323	CUGGGUUUGGAUCACAUAGca	CUAUGUGAUCCAAACCCAG	-2.1	-2.1	1.5	1	-1	3	-37	67.6	5.7	3	II	47.4	54.8	95.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0133	NM_003340	Huesken	UBE2D3	7323	GGGUUUGGAUCACAUAGCAgu	UGCUAUGUGAUCCAAACCC	-2.1	-3.3	1.5	0	-2	3	-38.3	51.7	-3.7	3	III	47.4	33.6	42.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0134	NM_003340	Huesken	UBE2D3	7323	UUGGAUCACAUAGCAGUGAac	UCACUGCUAUGUGAUCCAA	-2.4	-0.9	-3.4	1	0	2	-37.4	59.8	-1.1	6	II	42.1	60.8	95.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0135	NM_003340	Huesken	UBE2D3	7323	CAUAGCAGUGAACAAAUGGau	CCAUUUGUUCACUGCUAUG	-3.3	-2.1	1.1	-1	1	2	-34.4	65	2.7	5	II	42.1	57.5	94.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0136	NM_003340	Huesken	UBE2D3	7323	AUAGCAGUGAACAAAUGGAua	UCCAUUUGUUCACUGCUAU	-2.4	-1.1	1.1	2	2	2	-34.7	61.8	-6.4	6	II	36.8	56.1	98.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0137	NM_003340	Huesken	UBE2D3	7323	UAGCAGUGAACAAAUGGAUaa	AUCCAUUUGUUCACUGCUA	-1.1	-1.3	1.1	2	1	2	-34.7	63.7	-6.2	7	II	36.8	61.1	96.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0138	NM_003340	Huesken	UBE2D3	7323	GCAGUGAACAAAUGGAUAAaa	UUAUCCAUUUGUUCACUGC	-0.9	-3.4	2.3	0	-3	2	-33.5	57.5	-1.5	5	III	36.8	35.5	23.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0139	NM_003340	Huesken	UBE2D3	7323	GUGAACAAAUGGAUAAAAGaa	CUUUUAUCCAUUUGUUCAC	-2.1	-2.2	3	0	1	2	-29.8	71.2	2.4	4	II	31.6	48.7	27	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0140	NM_003340	Huesken	UBE2D3	7323	UGGAUAAAAGAACUUUAGAaa	UCUAAAGUUCUUUUAUCCA	-2.4	-2.1	2.3	0	0	2	-30.2	81.8	3.3	6	II	26.3	57.8	64.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0141	NM_003340	Huesken	UBE2D3	7323	GAUAAAAGAACUUUAGAAAuu	UUUCUAAAGUUCUUUUAUC	-0.9	-2.4	2.3	0	-1	1	-26.6	83	2	6	II	21.1	41.6	30.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0142	NM_003340	Huesken	UBE2D3	7323	AAAAGAACUUUAGAAAUUGuu	CAAUUUCUAAAGUUCUUUU	-2.1	-0.9	2.5	1	3	1	-25.9	73	0	7	Ia	21.1	68.5	80.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0143	NM_003340	Huesken	UBE2D3	7323	UUUAGAAAUUGUUAAAGCAgg	UGCUUUAACAAUUUCUAAA	-2.1	-0.9	1.9	0	2	2	-27.3	88.2	-0.7	7	II	21.1	67.6	92	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0144	NM_003340	Huesken	UBE2D3	7323	UUAGAAAUUGUUAAAGCAGgc	CUGCUUUAACAAUUUCUAA	-2.1	-0.9	1.8	0	4	2	-28.5	76.1	3.1	7	Ia	26.3	75.8	89.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0145	NM_003340	Huesken	UBE2D3	7323	AUUGUUAAAGCAGGCGACCac	GGUCGCCUGCUUUAACAAU	-3.3	-1.1	1.2	0	4	4	-37	59.1	5.1	6	Ia	47.4	67.5	84.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0146	NM_003340	Huesken	UBE2D3	7323	UUGUUAAAGCAGGCGACCAcu	UGGUCGCCUGCUUUAACAA	-2.1	-0.9	1.2	1	1	4	-38	63	-1.5	7	II	47.4	61.5	90.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0147	NM_003340	Huesken	UBE2D3	7323	UGUUAAAGCAGGCGACCACug	GUGGUCGCCUGCUUUAACA	-2.2	-2.1	-0.9	0	3	4	-39.3	58.6	12.5	8	Ia	52.6	57.2	100.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0148	NM_003340	Huesken	UBE2D3	7323	GGCGACCACUGUGAUCUUAga	UAAGAUCACAGUGGUCGCC	-1.3	-3.3	-3.4	1	-4	4	-40	42.6	2	1	III	52.6	21.3	55.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0149	NM_003340	Huesken	UBE2D3	7323	CGACCACUGUGAUCUUAGAau	UCUAAGAUCACAGUGGUCG	-2.4	-2.4	-3.4	1	-3	2	-37.8	51.6	-5.8	0	III	47.4	27.4	43.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0150	NM_003340	Huesken	UBE2D3	7323	UGAUCUUAGAAUAUCGAGAca	UCUCGAUAUUCUAAGAUCA	-2.4	-2.1	-0.5	2	1	2	-32.9	90.6	1.3	7	II	31.6	66.1	98.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0151	NM_003340	Huesken	UBE2D3	7323	GAAUAUCGAGACAAAUGCUgc	AGCAUUUGUCUCGAUAUUC	-2.1	-2.4	1.4	0	1	2	-33.3	62.7	-3.9	4	II	36.8	46.6	79.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0152	NM_003340	Huesken	UBE2D3	7323	AAUAUCGAGACAAAUGCUGcc	CAGCAUUUGUCUCGAUAUU	-2.1	-0.9	1.4	2	4	2	-33	71.4	-4.9	8	Ia	36.8	67.7	95.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0153	NM_003340	Huesken	UBE2D3	7323	AUCGAGACAAAUGCUGCCAuu	UGGCAGCAUUUGUCUCGAU	-2.1	-1.1	-1.7	1	1	3	-38.5	59.8	4.3	5	II	47.4	55.7	99.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0154	NM_003340	Huesken	UBE2D3	7323	ACAAAUGCUGCCAUUACUGuu	CAGUAAUGGCAGCAUUUGU	-2.1	-2.2	-0.4	1	4	3	-35.4	65.3	-2.3	6	Ia	42.1	63.7	97.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0155	NM_003340	Huesken	UBE2D3	7323	UGCUGCCAUUACUGUUAAUau	AUUAACAGUAAUGGCAGCA	-1.1	-2.1	-0.9	-1	-1	3	-34.6	70.9	-4	4	II	36.8	41.1	57.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0156	NM_003340	Huesken	UBE2D3	7323	CUGUUAAUAUUUGGAUGAUaa	AUCAUCCAAAUAUUAACAG	-1.1	-2.1	3.8	-2	-2	2	-29.3	69.7	-3	4	II	26.3	37.9	32	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0157	NM_003340	Huesken	UBE2D3	7323	UAAUAUUUGGAUGAUAAAUuc	AUUUAUCAUCCAAAUAUUA	-1.1	-1.3	2.5	2	1	2	-26.2	99.4	4.1	8	II	15.8	70.4	76.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0158	NM_003340	Huesken	UBE2D3	7323	UUUGGAUGAUAAAUUCUUGuu	CAAGAAUUUAUCAUCCAAA	-2.1	-0.9	1	1	4	2	-28.9	86.7	2	7	Ia	26.3	73.2	93.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0159	NM_003340	Huesken	UBE2D3	7323	GAUAAAUUCUUGUUGUAAAug	UUUACAACAAGAAUUUAUC	-0.9	-2.4	2.7	2	-1	1	-26.6	87.6	1.3	5	II	21.1	41.6	48.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0160	NM_003340	Huesken	UBE2D3	7323	AUAAAUUCUUGUUGUAAAUgc	AUUUACAACAAGAAUUUAU	-1.1	-1.1	2.4	1	1	1	-25.3	96.6	1.8	7	II	15.8	59.7	74.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0161	NM_003340	Huesken	UBE2D3	7323	UAAAUUCUUGUUGUAAAUGca	CAUUUACAACAAGAAUUUA	-2.1	-1.3	2.2	0	4	1	-26.3	97	5.4	7	Ia	21.1	78.7	70	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0162	NM_003340	Huesken	UBE2D3	7323	AAUUCUUGUUGUAAAUGCAac	UGCAUUUACAACAAGAAUU	-2.1	-0.9	1.9	2	2	2	-29.6	88.6	-3.3	6	II	26.3	58.9	83.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0163	NM_003340	Huesken	UBE2D3	7323	AUUCUUGUUGUAAAUGCAAcc	UUGCAUUUACAACAAGAAU	-0.9	-1.1	1.3	2	1	2	-29.6	73.3	-6.3	6	II	26.3	57	68.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0164	NM_003340	Huesken	UBE2D3	7323	CUUGUUGUAAAUGCAACCUua	AGGUUGCAUUUACAACAAG	-2.1	-2.1	-2.6	-1	0	2	-32.8	76.3	-0.7	4	II	36.8	57.3	86.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0165	NM_003340	Huesken	UBE2D3	7323	UUGUUGUAAAUGCAACCUUag	AAGGUUGCAUUUACAACAA	-0.9	-0.9	-2.6	1	1	2	-31.6	79.9	-1.6	7	II	31.6	70.7	83	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0166	NM_003340	Huesken	UBE2D3	7323	GUUGUAAAUGCAACCUUAGgu	CUAAGGUUGCAUUUACAAC	-2.1	-2.2	-0.9	0	1	2	-32	65.2	-4.9	5	II	36.8	51.4	80.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0167	NM_003340	Huesken	UBE2D3	7323	CAACCUUAGGUGGUUUGAAgg	UUCAAACCACCUAAGGUUG	-0.9	-2.1	-3	2	-1	2	-35.2	59.3	-3.4	2	II	42.1	39.2	64.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0168	NM_003340	Huesken	UBE2D3	7323	ACCUUAGGUGGUUUGAAGGgg	CCUUCAAACCACCUAAGGU	-3.3	-2.2	-1.4	1	3	2	-37.6	71.5	5.4	4	Ib	47.4	54.8	94.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0169	NM_003340	Huesken	UBE2D3	7323	GGUGGUUUGAAGGGGUAGUcu	ACUACCCCUUCAAACCACC	-2.2	-3.3		1	-1	4	-40.1	50.1	-1.7	3	III	52.6	35.6	63.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0170	NM_003340	Huesken	UBE2D3	7323	GUGGUUUGAAGGGGUAGUCug	GACUACCCCUUCAAACCAC	-2.4	-2.2	1.3	0	1	4	-39.2	55.3	7.4	4	II	52.6	48.6	87.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0171	NM_003340	Huesken	UBE2D3	7323	UUGAAGGGGUAGUCUGUAGga	CUACAGACUACCCCUUCAA	-2.1	-0.9	1.1	1	2	4	-38.3	68.4	5	8	Ib	47.4	62.9	94.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0172	NM_003340	Huesken	UBE2D3	7323	UGAAGGGGUAGUCUGUAGGaa	CCUACAGACUACCCCUUCA	-3.3	-2.1	1.1	0	4	4	-40.7	67.4	7.8	7	II	52.6	67	99.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0173	NM_003340	Huesken	UBE2D3	7323	UAGUCUGUAGGAAAAUGAAuu	UUCAUUUUCCUACAGACUA	-0.9	-1.3	2	0	0	2	-32.7	75.2	-6.3	6	II	31.6	55.7	85	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0174	NM_003340	Huesken	UBE2D3	7323	GUCUGUAGGAAAAUGAAUUgu	AAUUCAUUUUCCUACAGAC	-0.9	-2.2	2	1	-1	2	-31.3	74.3	-1.9	4	II	31.6	49.8	62.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0175	NM_003340	Huesken	UBE2D3	7323	CUGUAGGAAAAUGAAUUGUca	ACAAUUCAUUUUCCUACAG	-2.2	-2.1	3.5	-1	-2	2	-31	70.2	2.1	6	III	31.6	49.9	76.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0176	NM_003340	Huesken	UBE2D3	7323	UGUAGGAAAAUGAAUUGUCaa	GACAAUUCAUUUUCCUACA	-2.4	-2.1	1.3	0	3	2	-31.3	75.6	4.8	7	Ib	31.6	72.2	92.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0177	NM_003340	Huesken	UBE2D3	7323	GUAGGAAAAUGAAUUGUCAaa	UGACAAUUCAUUUUCCUAC	-2.1	-2.2	0.8	0	0	2	-31.3	62.6	-4	4	II	31.6	44.9	55.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0178	NM_003340	Huesken	UBE2D3	7323	AAAAGAAUACACCGCCUUGau	CAAGGCGGUGUAUUCUUUU	-2.1	-0.9	1	0	3	5	-34.5	65.6	2.4	7	Ia	42.1	61.3	104.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0179	NM_003340	Huesken	UBE2D3	7323	AGAAUACACCGCCUUGAUAug	UAUCAAGGCGGUGUAUUCU	-1.3	-2.1	0.1	2	0	5	-36.6	63.6	-1.4	5	II	42.1	42.2	99.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0180	NM_003340	Huesken	UBE2D3	7323	CUUGAUAUGGGCUGUCAUUag	AAUGACAGCCCAUAUCAAG	-0.9	-2.1	0.2	-1	-2	4	-36	63.2	-5.6	4	II	42.1	45.8	80	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0181	NM_003340	Huesken	UBE2D3	7323	UUGAUAUGGGCUGUCAUUAgg	UAAUGACAGCCCAUAUCAA	-1.3	-0.9	0.2	2	0	4	-35.2	78.2	-0.8	8	II	36.8	63.3	97.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0182	NM_003340	Huesken	UBE2D3	7323	GGGCUGUCAUUAGGUCCCAua	UGGGACCUAAUGACAGCCC	-2.1	-3.3	-1.2	1	-2	4	-42.9	31.6	-3.8	0	III	57.9	29.3	48.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0183	NM_003340	Huesken	UBE2D3	7323	GCUGUCAUUAGGUCCCAUAau	UAUGGGACCUAAUGACAGC	-1.3	-3.4	1.5	0	-3	3	-38.7	61.6	-3.8	4	III	47.4	36.9	44.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0184	NM_003340	Huesken	UBE2D3	7323	UGUCAUUAGGUCCCAUAAUug	AUUAUGGGACCUAAUGACA	-1.1	-2.1	0.5	3	0	3	-35.2	70.2	-1.2	6	II	36.8	56	64.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0185	NM_003340	Huesken	UBE2D3	7323	GGUCCCAUAAUUGUGGCUUgc	AAGCCACAAUUAUGGGACC	-0.9	-3.3	-1.6	1	0	3	-38	62.9	1.4	2	III	47.4	38.6	52	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0186	NM_003340	Huesken	UBE2D3	7323	GUCCCAUAAUUGUGGCUUGcc	CAAGCCACAAUUAUGGGAC	-2.1	-2.2	-1.6	1	0	3	-36.8	57.7	0	2	II	47.4	41.1	35.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0187	NM_003340	Huesken	UBE2D3	7323	UCCCAUAAUUGUGGCUUGCca	GCAAGCCACAAUUAUGGGA	-3.4	-2.4	-1.6	0	2	3	-38	63.1	13.1	5	Ib	47.4	59.2	75.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0188	NM_003340	Huesken	UBE2D3	7323	CCCAUAAUUGUGGCUUGCCaa	GGCAAGCCACAAUUAUGGG	-3.3	-3.3	-1.8	-1	0	3	-38.9	53.8	5.4	2	II	52.6	48.6	60.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0189	NM_003340	Huesken	UBE2D3	7323	UAAUUGUGGCUUGCCAAUGaa	CAUUGGCAAGCCACAAUUA	-2.1	-1.3	-2.4	2	3	3	-35.3	75.5	3	7	Ia	42.1	74.6	100.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0190	NM_003340	Huesken	UBE2D3	7323	UUGUGGCUUGCCAAUGAAAca	UUUCAUUGGCAAGCCACAA	-0.9	-0.9	-2.4	0	-1	3	-36.2	60.8	-11	4	II	42.1	52.6	85.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0191	NM_003340	Huesken	UBE2D3	7323	UGUGGCUUGCCAAUGAAACau	GUUUCAUUGGCAAGCCACA	-2.2	-2.1	-2.4	2	3	3	-37.5	67.8	4.8	4	II	47.4	63.5	94.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0192	NM_003340	Huesken	UBE2D3	7323	UGGCUUGCCAAUGAAACAUau	AUGUUUCAUUGGCAAGCCA	-1.1	-2.1	-1.9	2	0	3	-36.4	67.9	1.4	5	II	42.1	58	90.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0193	NM_003340	Huesken	UBE2D3	7323	GGCUUGCCAAUGAAACAUAuc	UAUGUUUCAUUGGCAAGCC	-1.3	-3.3	-0.9	0	-4	3	-35.6	50.8	-6.3	3	III	42.1	31.1	44.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0194	NM_003340	Huesken	UBE2D3	7323	GCCAAUGAAACAUAUCAUCcc	GAUGAUAUGUUUCAUUGGC	-2.4	-3.4	-2.8	0	-1	3	-32.9	65.4	7.8	3	II	36.8	48.3	66.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0195	NM_003340	Huesken	UBE2D3	7323	CAAUGAAACAUAUCAUCCCca	GGGAUGAUAUGUUUCAUUG	-3.3	-2.1	-3.2	0	2	3	-32.8	70.9	5.4	4	II	36.8	65	95	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0196	NM_003340	Huesken	UBE2D3	7323	AUAUCAUCCCCAACUGGACcu	GUCCAGUUGGGGAUGAUAU	-2.2	-1.1	-3.3	3	4	4	-38.7	67	2.5	5	Ia	47.4	60.7	88.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0197	NM_003340	Huesken	UBE2D3	7323	UAUCAUCCCCAACUGGACCug	GGUCCAGUUGGGGAUGAUA	-3.3	-1.3	-3.7	2	5	4	-40.9	72.5	17.1	5	Ia	52.6	71.8	93.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0198	NM_003340	Huesken	UBE2D3	7323	CCCCAACUGGACCUGCAGAac	UCUGCAGGUCCAGUUGGGG	-2.4	-3.3	-1.5	1	-3	4	-44.7	35.1	1.6	-1	III	63.2	24.7	32.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0199	NM_003340	Huesken	UBE2D3	7323	CCCAACUGGACCUGCAGAAca	UUCUGCAGGUCCAGUUGGG	-0.9	-3.3	-0.9	0	-4	3	-42.3	41.8	-7.8	3	III	57.9	27.3	50	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0200	NM_003340	Huesken	UBE2D3	7323	GACCUGCAGAACAUUGUGCug	GCACAAUGUUCUGCAGGUC	-3.4	-2.4	-1.8	2	2	2	-39.1	59.8	7.1	3	II	52.6	49	100.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0201	NM_003340	Huesken	UBE2D3	7323	ACCUGCAGAACAUUGUGCUgg	AGCACAAUGUUCUGCAGGU	-2.1	-2.2	-2	1	2	2	-38.8	65.1	-4	4	II	47.4	50.6	101.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0202	NM_003340	Huesken	UBE2D3	7323	CCUGCAGAACAUUGUGCUGga	CAGCACAAUGUUCUGCAGG	-2.1	-3.3	-2	-2	0	2	-38.7	51.2	3.3	1	II	52.6	36.8	87.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0203	NM_003337	Huesken	UBE2B	7320	CUUUGUUCAACAAUGGCCGaa	CGGCCAUUGUUGAACAAAG	-2.4	-2.1	-0.7	0	3	5	-35.3	73.2	-4.6	5	II	47.4	64.5	76.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0204	NM_003337	Huesken	UBE2B	7320	GUUCAACAAUGGCCGAAACuc	GUUUCGGCCAUUGUUGAAC	-2.2	-2.2	-3.1	1	1	5	-35.7	55.5	12.5	2	II	47.4	37.9	61.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0205	NM_003337	Huesken	UBE2B	7320	CAAUGGCCGAAACUCUUUUcu	AAAAGAGUUUCGGCCAUUG	-0.9	-2.1	1.5	0	-1	5	-34.3	66.2	1.1	5	III	42.1	46.5	49.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0206	NM_003337	Huesken	UBE2B	7320	AUGGCCGAAACUCUUUUCUca	AGAAAAGAGUUUCGGCCAU	-2.1	-1.1	-0.8	1	2	5	-35.8	78.2	1.4	6	II	42.1	59.6	77.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0207	NM_003337	Huesken	UBE2B	7320	UGGCCGAAACUCUUUUCUCau	GAGAAAAGAGUUUCGGCCA	-2.4	-2.1	-0.9	1	3	5	-37.1	69.2	7.4	4	II	47.4	64.5	82.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0208	NM_003337	Huesken	UBE2B	7320	CGAAACUCUUUUCUCAUAUuc	AUAUGAGAAAAGAGUUUCG	-1.1	-2.4	-0.9	0	-2	2	-30.6	79.4	4.5	5	II	31.6	45.4	46.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0209	NM_003337	Huesken	UBE2B	7320	AAACUCUUUUCUCAUAUUCuc	GAAUAUGAGAAAAGAGUUU	-2.4	-0.9	3	3	3	1	-29.1	94	10.5	7	Ia	26.3	70.5	78.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0210	NM_003337	Huesken	UBE2B	7320	ACUCUUUUCUCAUAUUCUCgu	GAGAAUAUGAGAAAAGAGU	-2.4	-2.2	4.5	4	3	1	-31.8	85.3	5.1	5	Ia	31.6	63.6	83.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0211	NM_003337	Huesken	UBE2B	7320	CUCUUUUCUCAUAUUCUCGuu	CGAGAAUAUGAGAAAAGAG	-2.4	-2.1	3.1	0	1	2	-32	93.5	3.1	5	II	36.8	64.4	73.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0212	NM_003337	Huesken	UBE2B	7320	UCUUUUCUCAUAUUCUCGUuu	ACGAGAAUAUGAGAAAAGA	-2.2	-2.4	2.6	1	3	2	-32.1	93.7	-1.6	7	II	31.6	67.2	84.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0213	NM_003337	Huesken	UBE2B	7320	AUUCUCGUUUGUUUUCCUGau	CAGGAAAACAAACGAGAAU	-2.1	-1.1		2	5	2	-32.2	88.7	5.4	6	Ib	36.8	64.2	84	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0214	NM_003337	Huesken	UBE2B	7320	UUUGUUUUCCUGAUAAAGCug	GCUUUAUCAGGAAAACAAA	-3.4	-0.9	1.4	2	5	2	-30.8	94.1	7.1	7	Ia	31.6	84.8	80.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0215	NM_003337	Huesken	UBE2B	7320	UUUCCUGAUAAAGCUGUGCug	GCACAGCUUUAUCAGGAAA	-3.4	-0.9	1.1	1	4	2	-35.7	79.5	9.7	8	Ib	42.1	75.9	83.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0216	NM_003337	Huesken	UBE2B	7320	UCCUGAUAAAGCUGUGCUGcc	CAGCACAGCUUUAUCAGGA	-2.1	-2.4	0.3	0	2	2	-38.1	66.5	-2.4	6	Ib	47.4	57.3	77.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0217	NM_003337	Huesken	UBE2B	7320	GAUAAAGCUGUGCUGCCUGgc	CAGGCAGCACAGCUUUAUC	-2.1	-2.4	-2.1	0	3	3	-39.1	54.8	7.4	4	II	52.6	49.5	75.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0218	NM_003337	Huesken	UBE2B	7320	AAAGCUGUGCUGCCUGGCUau	AGCCAGGCAGCACAGCUUU	-2.1	-0.9	-2.1	2	3	3	-43.1	53.3	-1.6	3	II	57.9	55.9	71.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0219	NM_003337	Huesken	UBE2B	7320	AGCUGUGCUGCCUGGCUAUug	AUAGCCAGGCAGCACAGCU	-1.1	-2.1	-1.4	0	-1	3	-43.7	49.5	-8.7	3	II	57.9	38.3	71.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0220	NM_003337	Huesken	UBE2B	7320	GCUGUGCUGCCUGGCUAUUgg	AAUAGCCAGGCAGCACAGC	-0.9	-3.4	-0.9	0	-2	3	-42.5	37.1	-3.3	1	III	57.9	24.4	51	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0221	NM_003337	Huesken	UBE2B	7320	UGCUGCCUGGCUAUUGGCUgg	AGCCAAUAGCCAGGCAGCA	-2.1	-2.1	-4.5	1	2	3	-43.6	59.9	-3.6	2	II	57.9	50.8	75.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0222	NM_003337	Huesken	UBE2B	7320	CCUGGCUAUUGGCUGGACUgu	AGUCCAGCCAAUAGCCAGG	-2.1	-3.3	0.2	0	-1	3	-42.6	50.8	-1.2	1	III	57.9	38.1	68.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0223	NM_003337	Huesken	UBE2B	7320	GGACUGUUAGGAUUCGGUUca	AACCGAAUCCUAACAGUCC	-0.9	-3.3	2.7	2	0	3	-37.5	59.8	-1.6	3	III	47.4	39.9	49.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0224	NM_003337	Huesken	UBE2B	7320	GACUGUUAGGAUUCGGUUCau	GAACCGAAUCCUAACAGUC	-2.4	-2.4	1.9	2	0	3	-36.6	76	12.7	4	II	47.4	51.3	72.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0225	NM_003337	Huesken	UBE2B	7320	UUAGGAUUCGGUUCAUCCAgc	UGGAUGAACCGAAUCCUAA	-2.1	-0.9	-3.5	2	2	3	-36.6	75.1	-0.7	5	II	42.1	66.4	74.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0226	NM_003337	Huesken	UBE2B	7320	AGGAUUCGGUUCAUCCAGCag	GCUGGAUGAACCGAAUCCU	-3.4	-2.1	-3.5	2	3	3	-39.9	58.5	4.8	3	Ib	52.6	58.2	81.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0227	NM_003337	Huesken	UBE2B	7320	GGUUCAUCCAGCAGAGACUga	AGUCUCUGCUGGAUGAACC	-2.1	-3.3	-0.8	1	-1	2	-40.7	55.2	-8.9	4	II	52.6	38.1	53.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0228	NM_003337	Huesken	UBE2B	7320	UUCAUCCAGCAGAGACUGAau	UCAGUCUCUGCUGGAUGAA	-2.4	-0.9	-2.9	0	0	2	-39.7	58.8	-4	6	II	47.4	50.9	62.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0229	NM_003337	Huesken	UBE2B	7320	AUCCAGCAGAGACUGAAUUga	AAUUCAGUCUCUGCUGGAU	-0.9	-1.1	-4.8	3	1	2	-37.2	61	3.5	4	II	42.1	51.2	60.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0230	NM_003337	Huesken	UBE2B	7320	CUGAAUUGAUGUUAAGAUAga	UAUCUUAACAUCAAUUCAG	-1.3	-2.1	4	0	-4	1	-29.4	79.2	0	4	II	26.3	45.7	50.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0231	NM_003337	Huesken	UBE2B	7320	UUAAGAUAGAAGAUACAUCau	GAUGUAUCUUCUAUCUUAA	-2.4	-0.9	-0.1	2	4	1	-30.1	87	9.4	8	Ia	26.3	81.1	84.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0232	NM_003337	Huesken	UBE2B	7320	AUAGAAGAUACAUCAUAUGuu	CAUAUGAUGUAUCUUCUAU	-2.1	-1.1	1.2	1	3	1	-30.2	73.4	0.4	7	Ia	26.3	67.4	83.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0233	NM_003337	Huesken	UBE2B	7320	AUACAUCAUAUGUUGGACUcc	AGUCCAACAUAUGAUGUAU	-2.1	-1.1	0.3	2	3	2	-33.1	79.2	1.1	6	II	31.6	65.8	83.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0234	NM_003337	Huesken	UBE2B	7320	AUGUUGGACUCCAUCGAUUcu	AAUCGAUGGAGUCCAACAU	-0.9	-1.1	-0.3	2	1	2	-36.5	66.1	-8.9	6	II	42.1	56.6	74.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0235	NM_003337	Huesken	UBE2B	7320	UGUUGGACUCCAUCGAUUCug	GAAUCGAUGGAGUCCAACA	-2.4	-2.1	-0.3	0	2	2	-37.8	72	5.1	7	Ib	47.4	67.1	84.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0236	NM_003337	Huesken	UBE2B	7320	GUUGGACUCCAUCGAUUCUga	AGAAUCGAUGGAGUCCAAC	-2.1	-2.2	-0.3	0	0	2	-37.8	57.5	3.8	3	III	47.4	37	64.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0237	NM_003337	Huesken	UBE2B	7320	UUGGACUCCAUCGAUUCUGaa	CAGAAUCGAUGGAGUCCAA	-2.1	-0.9	-0.3	2	3	2	-37.7	67.8	0.4	7	Ib	47.4	74.5	86.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0238	NM_003337	Huesken	UBE2B	7320	GACUCCAUCGAUUCUGAAGga	CUUCAGAAUCGAUGGAGUC	-2.1	-2.4	-2.8	1	0	2	-36.8	78.3	5.3	2	II	47.4	44.7	72.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0239	NM_003337	Huesken	UBE2B	7320	CUCCAUCGAUUCUGAAGGAua	UCCUUCAGAAUCGAUGGAG	-2.4	-2.1	-2.5	-1	-2	2	-37.9	45.1	-5.4	1	III	47.4	31.7	50	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0240	NM_003337	Huesken	UBE2B	7320	UCCAUCGAUUCUGAAGGAUau	AUCCUUCAGAAUCGAUGGA	-1.1	-2.4	-0.8	0	0	2	-36.9	60.1	-3.3	6	II	42.1	46.7	77.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0241	NM_003337	Huesken	UBE2B	7320	CGAUUCUGAAGGAUAUCUAaa	UAGAUAUCCUUCAGAAUCG	-1.3	-2.4	0	0	-2	2	-33.8	71	-6	5	II	36.8	41.6	47.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0242	NM_003337	Huesken	UBE2B	7320	CUGAAGGAUAUCUAAACAUau	AUGUUUAGAUAUCCUUCAG	-1.1	-2.1	0	-1	-2	2	-31.8	64.2	-5.6	5	III	31.6	51.3	46.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0243	NM_003337	Huesken	UBE2B	7320	UGAAGGAUAUCUAAACAUAug	UAUGUUUAGAUAUCCUUCA	-1.3	-2.1	0	0	-1	2	-31	71.2	-5.7	6	II	26.3	58.3	63.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0244	NM_003337	Huesken	UBE2B	7320	UCUAAACAUAUGCUACCAUca	AUGGUAGCAUAUGUUUAGA	-1.1	-2.4	0.8	0	2	2	-33	71.8	3.5	7	II	31.6	54.8	69.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0245	NM_003337	Huesken	UBE2B	7320	UAUGCUACCAUCAGCAUACac	GUAUGCUGAUGGUAGCAUA	-2.2	-1.3	-5.4	0	3	2	-36.7	77.8	2.5	7	Ia	42.1	75.7	75.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0246	NM_003337	Huesken	UBE2B	7320	CCAUCAGCAUACACAUUUGga	CAAAUGUGUAUGCUGAUGG	-2.1	-3.3	1.2	-1	-1	2	-34.6	61.7	-4.6	4	II	42.1	43.3	62.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0247	NM_003337	Huesken	UBE2B	7320	UCAGCAUACACAUUUGGAUga	AUCCAAAUGUGUAUGCUGA	-1.1	-2.4	1.2	2	2	2	-34.9	74.6	-4	6	II	36.8	57.6	73	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0248	NM_003337	Huesken	UBE2B	7320	GCAUACACAUUUGGAUGAAac	UUCAUCCAAAUGUGUAUGC	-0.9	-3.4	1.2	-1	-2	2	-33.7	50.5	2	4	II	36.8	23.5	46	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0249	NM_003337	Huesken	UBE2B	7320	CACAUUUGGAUGAAACAUUuu	AAUGUUUCAUCCAAAUGUG	-0.9	-2.1	0.7	1	-3	2	-30.8	71.3	-8.6	5	II	31.6	53.7	63.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0250	NM_003337	Huesken	UBE2B	7320	UUUGGAUGAAACAUUUUGGau	CCAAAAUGUUUCAUCCAAA	-3.3	-0.9	2.2	1	5	2	-30.5	90.2	-0.3	8	Ia	31.6	78	84.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0251	NM_003337	Huesken	UBE2B	7320	GGAUGAAACAUUUUGGAUAaa	UAUCCAAAAUGUUUCAUCC	-1.3	-3.3	2.6	1	-2	2	-31.4	72.3	1.6	4	II	31.6	40.7	48.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0252	NM_003337	Huesken	UBE2B	7320	AAAACCUAACAGUUGGUGGuu	CCACCAACUGUUAGGUUUU	-3.3	-0.9	-1.3	2	5	2	-35	85.9	4.6	6	Ia	42.1	67.4	69.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0253	NM_003337	Huesken	UBE2B	7320	AGUUGGUGGUUUAUUUGGAua	UCCAAAUAAACCACCAACU	-2.4	-2.1		3	2	2	-34.2	69.7	-1	5	II	36.8	47.4	61.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0254	NM_003337	Huesken	UBE2B	7320	GUUUAUUUGGAUAUUCUUCag	GAAGAAUAUCCAAAUAAAC	-2.4	-2.2	1.9	2	2	2	-28.2	98.8	15.2	6	II	26.3	62.6	77.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0255	NM_003337	Huesken	UBE2B	7320	UUAUUUGGAUAUUCUUCAGaa	CUGAAGAAUAUCCAAAUAA	-2.1	-0.9	1.9	0	4	2	-29.3	100.7	5.3	8	Ia	26.3	71.9	80.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0256	NM_003337	Huesken	UBE2B	7320	UUUGGAUAUUCUUCAGAAAau	UUUCUGAAGAAUAUCCAAA	-0.9	-0.9	0.3	1	0	2	-30.2	81.1	-3.1	6	II	26.3	56.3	82.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0257	NM_003337	Huesken	UBE2B	7320	UUGGAUAUUCUUCAGAAAAuu	UUUUCUGAAGAAUAUCCAA	-0.9	-0.9	0.3	0	-1	2	-30.2	81.7	4.4	6	II	26.3	64.1	85.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0258	NM_003337	Huesken	UBE2B	7320	UGGAUAUUCUUCAGAAAAUuc	AUUUUCUGAAGAAUAUCCA	-1.1	-2.1	0.3	1	-1	2	-30.4	75.7	-8.9	6	II	26.3	56.2	63.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0259	NM_003337	Huesken	UBE2B	7320	UCAGAAAAUUCUAUUACUAgu	UAGUAAUAGAAUUUUCUGA	-1.3	-2.4	-0.8	0	1	1	-28.4	76.1	-0.6	6	II	21.1	58.8	72.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0260	NM_003337	Huesken	UBE2B	7320	AAAAUUCUAUUACUAGUUUaa	AAACUAGUAAUAGAAUUUU	-0.9	-0.9	-2	1	2	1	-25.5	93.2	0.8	6	II	15.8	61.1	47.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0261	NM_003337	Huesken	UBE2B	7320	AAUUCUAUUACUAGUUUAAaa	UUAAACUAGUAAUAGAAUU	-0.9	-0.9	-2	0	0	1	-25.9	99.5	-5.7	7	II	15.8	55.5	46.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0262	NM_003337	Huesken	UBE2B	7320	AUUACUAGUUUAAAAGUACca	GUACUUUUAAACUAGUAAU	-2.2	-1.1	-1.3	1	3	1	-26.8	86.3	4.8	6	Ia	21.1	69.8	86.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0263	NM_003337	Huesken	UBE2B	7320	AUCUUCAAAAGGUGUCCCUuc	AGGGACACCUUUUGAAGAU	-2.1	-1.1	-1.8	0	2	3	-36.7	74.8	-4	6	II	42.1	57.8	78.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0264	NM_003337	Huesken	UBE2B	7320	CUUCAAAAGGUGUCCCUUCug	GAAGGGACACCUUUUGAAG	-2.4	-2.1	-4	1	0	3	-36.5	58.8	8.1	4	II	47.4	55.6	79.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0265	NM_003337	Huesken	UBE2B	7320	UUCUGGUCCAAAUAUAACUgc	AGUUAUAUUUGGACCAGAA	-2.1	-0.9	0.8	2	1	2	-32.6	89.6	-1.7	7	II	31.6	75.2	79	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0266	NM_003337	Huesken	UBE2B	7320	UGGUCCAAAUAUAACUGCAuu	UGCAGUUAUAUUUGGACCA	-2.1	-2.1	0.1	0	0	2	-34.8	76	-1	5	II	36.8	56.8	81.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0267	NM_003337	Huesken	UBE2B	7320	GGUCCAAAUAUAACUGCAUuc	AUGCAGUUAUAUUUGGACC	-1.1	-3.3	0.1	1	-1	2	-33.8	56.9	-6.6	3	III	36.8	37.1	53.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0268	NM_003337	Huesken	UBE2B	7320	AAAUAUAACUGCAUUCCACug	GUGGAAUGCAGUUAUAUUU	-2.2	-0.9	0.7	2	5	2	-31.4	83.4	7.5	7	Ia	31.6	67.9	84.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0269	NM_003337	Huesken	UBE2B	7320	AUAUAACUGCAUUCCACUGca	CAGUGGAAUGCAGUUAUAU	-2.1	-1.1	0.5	2	4	2	-33.8	79.5	8	6	Ia	36.8	63.5	83.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0270	NM_003337	Huesken	UBE2B	7320	CAUUCCACUGCAUGAUGUUgu	AACAUCAUGCAGUGGAAUG	-0.9	-2.1	-0.1	-2	-1	2	-35.7	63.8	-8.3	4	II	42.1	40.7	55	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0271	NM_003337	Huesken	UBE2B	7320	UCCACUGCAUGAUGUUGUUuu	AACAACAUCAUGCAGUGGA	-0.9	-2.4	-0.1	-1	0	2	-36.8	67.9	-4	5	II	42.1	47.1	56.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0272	NM_003337	Huesken	UBE2B	7320	GCAUGAUGUUGUUUUCAGAug	UCUGAAAACAACAUCAUGC	-2.4	-3.4	0.6	1	-1	2	-33.4	69.2	1.6	3	II	36.8	34.4	48.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0273	NM_003337	Huesken	UBE2B	7320	GAUGUUGUUUUCAGAUGGUgc	ACCAUCUGAAAACAACAUC	-2.2	-2.4	2	-1	1	2	-33.4	60.5	-8.9	4	II	36.8	43	50.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0274	NM_003337	Huesken	UBE2B	7320	UGUUGUUUUCAGAUGGUGCgc	GCACCAUCUGAAAACAACA	-3.4	-2.1	2	1	4	2	-35.4	88.5	9.4	7	Ia	42.1	72.5	74.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0275	NM_003337	Huesken	UBE2B	7320	UUGUUUUCAGAUGGUGCGCca	GCGCACCAUCUGAAAACAA	-3.4	-0.9	2	0	4	4	-36.9	79	12.7	7	Ia	47.4	72.2	72.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0276	NM_003337	Huesken	UBE2B	7320	UUCAGAUGGUGCGCCACUGac	CAGUGGCGCACCAUCUGAA	-2.1	-0.9	-2.2	2	3	5	-41.7	55.1	-2.4	4	Ia	57.9	63.7	61.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0277	NM_003337	Huesken	UBE2B	7320	GCCACUGACACCCACAGGUgg	ACCUGUGGGUGUCAGUGGC	-2.2	-3.4	-1.9	1	-1	3	-44.7	43.7	-6.3	1	III	63.2	37.3	76.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0278	NM_003337	Huesken	UBE2B	7320	CACAGGUGGGUCCUCUUGUaa	ACAAGAGGACCCACCUGUG	-2.2	-2.1	-1.5	1	-1	3	-42.4	52.3	-3.6	2	III	57.9	45.7	61.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0279	NM_003337	Huesken	UBE2B	7320	CUCUUGUAACCGCUUGAAAuc	UUUCAAGCGGUUACAAGAG	-0.9	-2.1	2.3	0	-3	4	-34.6	67.4	-3.4	4	II	42.1	36.2	45.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0280	NM_003337	Huesken	UBE2B	7320	UCUUGUAACCGCUUGAAAUcc	AUUUCAAGCGGUUACAAGA	-1.1	-2.4	2.3	1	1	4	-33.6	83.3	-4	6	II	36.8	58.1	78.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0281	NM_003337	Huesken	UBE2B	7320	GUAACCGCUUGAAAUCCCGca	CGGGAUUUCAAGCGGUUAC	-2.4	-2.2	0.8	0	3	4	-37.5	55.1	-2.6	4	II	52.6	54.8	85.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0282	NM_003969	Huesken	UBE2M	9040	GGAGCCGAUGUAGCCACCCcg	GGGUGGCUACAUCGGCUCC	-3.3	-3.3	-3.5	0	2	4	-45.7	31.7	7.4	0	II	68.4	47.8	58.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0283	NM_003969	Huesken	UBE2M	9040	AGCCGAUGUAGCCACCCCGca	CGGGGUGGCUACAUCGGCU	-2.4	-2.1	-3.5	3	3	5	-45.7	41.5	0.1	2	II	68.4	55.9	54.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0284	NM_003969	Huesken	UBE2M	9040	GAUGUAGCCACCCCGCAUGga	CAUGCGGGGUGGCUACAUC	-2.1	-2.4	-1.8	1	1	6	-43.2	48.8	-2.3	3	II	63.2	47.5	67.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0285	NM_003969	Huesken	UBE2M	9040	GCAUGGAGCGCUGCACGUUcu	AACGUGCAGCGCUCCAUGC	-0.9	-3.4	-1	1	-1	4	-43.1	31.2	-3.3	1	III	63.2	31.5	61.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0286	NM_003969	Huesken	UBE2M	9040	UUCUGCUCAAACAGCCGCCgg	GGCGGCUGUUUGAGCAGAA	-3.3	-0.9	-3	0	4	6	-41.5	65.9	4.8	5	Ib	57.9	72.7	76.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0287	NM_003969	Huesken	UBE2M	9040	AACAGCCGCCGGUUGUUCUgc	AGAACAACCGGCGGCUGUU	-2.1	-0.9	0.8	2	2	8	-41.6	63.6	-1.6	4	II	57.9	49.4	61.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0288	NM_003969	Huesken	UBE2M	9040	AGCCGCCGGUUGUUCUGCAgg	UGCAGAACAACCGGCGGCU	-2.1	-2.1	0	3	1	8	-44	40.3	-1.4	1	II	63.2	35.1	67.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0289	NM_003969	Huesken	UBE2M	9040	GCCGCCGGUUGUUCUGCAGga	CUGCAGAACAACCGGCGGC	-2.1	-3.4	-2.2	0	0	8	-44	42.6	3	-1	II	68.4	27.7	64.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0290	NM_003969	Huesken	UBE2M	9040	UGUUCUGCAGGACCUCUGCgg	GCAGAGGUCCUGCAGAACA	-3.4	-2.1	-5.2	0	3	2	-42.7	69.9	9.8	5	Ib	57.9	64	69.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0291	NM_003969	Huesken	UBE2M	9040	UUCUGCAGGACCUCUGCGGcc	CCGCAGAGGUCCUGCAGAA	-3.3	-0.9	-5.5	1	4	4	-44.1	61.8	-4.7	5	Ib	63.2	67.6	67.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0292	NM_003969	Huesken	UBE2M	9040	CUGCAGGACCUCUGCGGCCuc	GGCCGCAGAGGUCCUGCAG	-3.3	-2.1	-5.5	0	1	6	-47.5	29.2	5.8	1	II	73.7	49	66.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0293	NM_003969	Huesken	UBE2M	9040	UGCAGGACCUCUGCGGCCUcc	AGGCCGCAGAGGUCCUGCA	-2.1	-2.1	-5.5	1	1	6	-47.5	44.3	-3.3	3	II	68.4	53.3	65.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0294	NM_003969	Huesken	UBE2M	9040	UCUGCGGCCUCCUUGUUCAgu	UGAACAAGGAGGCCGCAGA	-2.1	-2.4	0.5	1	1	6	-42.9	61.2	-6.1	5	II	57.9	53.1	65.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0295	NM_003969	Huesken	UBE2M	9040	CUGCGGCCUCCUUGUUCAGug	CUGAACAAGGAGGCCGCAG	-2.1	-2.1	0.5	-1	0	6	-42.6	40.7	-1.3	0	II	63.2	35.6	68.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0296	NM_003969	Huesken	UBE2M	9040	CUCCUUGUUCAGUGGGUCCuc	GGACCCACUGAACAAGGAG	-3.3	-2.1	0.2	-1	0	3	-41.4	61	7.7	3	II	57.9	52.3	63.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0297	NM_003969	Huesken	UBE2M	9040	CAGUGGGUCCUCGGGGUUGgg	CAACCCCGAGGACCCACUG	-2.1	-2.1	-0.3	-1	-1	5	-45	34.2	-4.4	3	II	68.4	42.2	62.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0298	NM_003969	Huesken	UBE2M	9040	CUCGGGGUUGGGCUCCAAGaa	CUUGGAGCCCAACCCCGAG	-2.1	-2.1	-3.2	-1	0	5	-44.9	39.9	2.7	0	II	68.4	42.8	64.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0299	NM_003969	Huesken	UBE2M	9040	GGGGUUGGGCUCCAAGAAGag	CUUCUUGGAGCCCAACCCC	-2.1	-3.3	-0.7	1	-1	4	-43.4	33.8	0.1	1	II	63.2	35.5	61.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0300	NM_003969	Huesken	UBE2M	9040	GGGUUGGGCUCCAAGAAGAga	UCUUCUUGGAGCCCAACCC	-2.4	-3.3	-0.7	1	-3	4	-42.5	38.2	-11	2	III	57.9	31.3	56.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0301	NM_003969	Huesken	UBE2M	9040	GUUGGGCUCCAAGAAGAGAua	UCUCUUCUUGGAGCCCAAC	-2.4	-2.2	-2.3	1	-1	4	-40.4	38.6	-1.5	1	III	52.6	33.9	69.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0302	NM_003969	Huesken	UBE2M	9040	UUGGGCUCCAAGAAGAGAUac	AUCUCUUCUUGGAGCCCAA	-1.1	-0.9	-2.3	2	1	4	-39.3	65.5	-4.3	5	II	47.4	63.8	77.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0303	NM_003969	Huesken	UBE2M	9040	AGAAGAGAUACUGCAGGCCau	GGCCUGCAGUAUCUCUUCU	-3.3	-2.1	1.5	1	4	4	-40.8	50.9	8.1	6	Ib	52.6	59.8	80.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0304	NM_003969	Huesken	UBE2M	9040	UACUGCAGGCCAUAAAUUAug	UAAUUUAUGGCCUGCAGUA	-1.3	-1.3	1.5	1	-1	4	-34.9	69.4	-6.1	7	II	36.8	56.7	67	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0305	NM_003969	Huesken	UBE2M	9040	GGCCAUAAAUUAUGGAGUUua	AACUCCAUAAUUUAUGGCC	-0.9	-3.3	-2.1	0	-2	4	-33.7	52.9	-1.3	1	III	36.8	32.3	49.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0306	NM_003969	Huesken	UBE2M	9040	AAAUUAUGGAGUUUAUCGUaa	ACGAUAAACUCCAUAAUUU	-2.2	-0.9	1.8	3	4	2	-29.5	94.4	1.4	8	II	26.3	64.4	82.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0307	NM_003969	Huesken	UBE2M	9040	UGGAGUUUAUCGUAAGGACug	GUCCUUACGAUAAACUCCA	-2.2	-2.1	0.7	1	2	2	-35.5	73.4	5.1	5	Ib	42.1	61.6	76.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0308	NM_003969	Huesken	UBE2M	9040	GGAGUUUAUCGUAAGGACUgg	AGUCCUUACGAUAAACUCC	-2.1	-3.3	0.4	1	-1	2	-35.5	64.1	-3.5	3	II	42.1	47.5	60.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0309	NM_003969	Huesken	UBE2M	9040	GUUUAUCGUAAGGACUGGCuu	GCCAGUCCUUACGAUAAAC	-3.4	-2.2	0.4	0	3	3	-36.5	64.2	12.4	5	II	47.4	52.4	68.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0310	NM_003969	Huesken	UBE2M	9040	AGGACUGGCUUCCAGUCCUcu	AGGACUGGAAGCCAGUCCU	-2.1	-2.1	-11.3	2	1	3	-43.8	51.8	-3.9	2	II	57.9	51.2	54.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0311	NM_003969	Huesken	UBE2M	9040	AGGAUGUUGAGGCAGACGUug	ACGUCUGCCUCAACAUCCU	-2.2	-2.1	1.2	3	1	3	-40.8	60.9	-1.6	6	II	52.6	55.3	80.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0312	NM_003969	Huesken	UBE2M	9040	UUGAGGCAGACGUUGCCCUcg	AGGGCAACGUCUGCCUCAA	-2.1	-0.9	-5.7	1	3	4	-42.7	58.5	-4	4	II	57.9	64.3	79.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0313	NM_003969	Huesken	UBE2M	9040	CGAGGUCAAUGUUGGGGUGau	CACCCCAACAUUGACCUCG	-2.1	-2.4	1.8	-2	0	4	-40.4	43.8	1	0	II	57.9	34.4	62.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0314	NM_003969	Huesken	UBE2M	9040	GAGGUCAAUGUUGGGGUGAua	UCACCCCAACAUUGACCUC	-2.4	-2.4	1.7	-1	-2	4	-40.4	44.6	-0.7	4	III	52.6	35.7	65.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0315	NM_003969	Huesken	UBE2M	9040	AAUGUUGGGGUGAUAGACCau	GGUCUAUCACCCCAACAUU	-3.3	-0.9	-0.8	2	5	4	-38.3	64.3	7.1	6	Ia	47.4	70.1	79.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0316	NM_003969	Huesken	UBE2M	9040	UGUUGGGGUGAUAGACCAUug	AUGGUCUAUCACCCCAACA	-1.1	-2.1	-0.8	-1	1	4	-39.5	53.8	-1.2	6	II	47.4	48.8	71.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0317	NM_003969	Huesken	UBE2M	9040	UUGGGGUGAUAGACCAUUGuc	CAAUGGUCUAUCACCCCAA	-2.1	-0.9	-0.8	1	2	4	-38.2	65.2	-0.3	6	II	47.4	70.2	86.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0318	NM_003969	Huesken	UBE2M	9040	GGGGUGAUAGACCAUUGUCuc	GACAAUGGUCUAUCACCCC	-2.4	-3.3	-1.6	0	0	4	-39.8	53.1	9.8	1	II	52.6	44	61.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0319	NM_003969	Huesken	UBE2M	9040	UAGACCAUUGUCUCACACUuc	AGUGUGAGACAAUGGUCUA	-2.1	-1.3	-3.1	0	1	2	-37.3	77.7	-6.3	5	II	42.1	70.5	92.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0320	NM_003969	Huesken	UBE2M	9040	CAUUGUCUCACACUUCACCuu	GGUGAAGUGUGAGACAAUG	-3.3	-2.1	0.8	0	2	2	-36.9	75.2	7.8	4	II	47.4	59.4	81.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0321	NM_003969	Huesken	UBE2M	9040	CAUGCGGGUAACCCUGGCCca	GGCCAGGGUUACCCGCAUG	-3.3	-2.1	-2.8	-1	2	5	-45.1	48.1	7.8	2	II	68.4	53.5	73.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0322	NM_003969	Huesken	UBE2M	9040	AUGCGGGUAACCCUGGCCCac	GGGCCAGGGUUACCCGCAU	-3.3	-1.1	-3	2	5	5	-46.3	48.5	7.4	3	II	68.4	64.4	79.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0323	NM_003969	Huesken	UBE2M	9040	GCGGGUAACCCUGGCCCACcu	GUGGGCCAGGGUUACCCGC	-2.2	-3.4	-5.2	0	0	5	-47.4	23.4	8.1	-1	II	73.7	32.8	56.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0324	NM_003969	Huesken	UBE2M	9040	GUAACCCUGGCCCACCUUAaa	UAAGGUGGGCCAGGGUUAC	-1.3	-2.2	-1.8	1	-2	5	-42.6	48.3	-6.1	2	III	57.9	36.3	69.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0325	NM_003969	Huesken	UBE2M	9040	GCCCACCUUAAAACUGAACac	GUUCAGUUUUAAGGUGGGC	-2.2	-3.4	-0.4	1	-1	4	-36.5	54.4	9.8	2	II	47.4	36.5	53.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0326	NM_003969	Huesken	UBE2M	9040	CCUUAAAACUGAACACAAAcu	UUUGUGUUCAGUUUUAAGG	-0.9	-3.3	1.1	0	-4	2	-30.4	57.4	-5.6	4	II	31.6	31.7	51.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0327	NM_003969	Huesken	UBE2M	9040	ACACAAACUUCCCACUCUUgu	AAGAGUGGGAAGUUUGUGU	-0.9	-2.2	2	2	1	3	-36.4	52.1	-3.6	5	II	42.1	48.6	85.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0328	NM_003969	Huesken	UBE2M	9040	AAACUUCCCACUCUUGUAGaa	CUACAAGAGUGGGAAGUUU	-2.1	-0.9	-2.5	3	4	3	-35.5	82.6	5.4	6	Ia	42.1	62.1	87.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0329	NM_003969	Huesken	UBE2M	9040	ACUUCCCACUCUUGUAGAAgc	UUCUACAAGAGUGGGAAGU	-0.9	-2.2	-4.3	1	0	3	-37	65.4	-3.1	3	II	42.1	31.2	68.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0330	NM_003969	Huesken	UBE2M	9040	CUUCCCACUCUUGUAGAAGcc	CUUCUACAAGAGUGGGAAG	-2.1	-2.1	-4.4	0	1	3	-36.9	63.8	3.4	2	II	47.4	48.2	75.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0331	NM_003969	Huesken	UBE2M	9040	UCUUGUAGAAGCCCUCAUCag	GAUGAGGGCUUCUACAAGA	-2.4	-2.4	0.9	0	2	4	-38.6	74.7	7.5	7	Ia	47.4	66.8	82.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0332	NM_003969	Huesken	UBE2M	9040	UGUAGAAGCCCUCAUCAGGac	CCUGAUGAGGGCUUCUACA	-3.3	-2.1	-1.8	1	3	4	-40.7	62	3.1	5	Ia	52.6	63.2	77.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0333	NM_003969	Huesken	UBE2M	9040	UAGAAGCCCUCAUCAGGACag	GUCCUGAUGAGGGCUUCUA	-2.2	-1.3	-5.7	1	3	4	-41	58.9	7.8	5	Ib	52.6	59.8	80.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0334	NM_003969	Huesken	UBE2M	9040	CCCUCAUCAGGACAGAUGAcc	UCAUCUGUCCUGAUGAGGG	-2.4	-3.3	-4.9	0	-4	3	-41	52.8	-3.4	2	III	52.6	32.5	57.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0335	NM_003969	Huesken	UBE2M	9040	CCUCAUCAGGACAGAUGACca	GUCAUCUGUCCUGAUGAGG	-2.2	-3.3	-5.1	0	0	2	-39.9	40.9	5.5	1	II	52.6	34.3	58.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0336	NM_003969	Huesken	UBE2M	9040	CAUCAGGACAGAUGACCAGcu	CUGGUCAUCUGUCCUGAUG	-2.1	-2.1	-2.3	0	1	2	-39.6	46.4	0.7	4	II	52.6	45.3	76.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0337	NM_003969	Huesken	UBE2M	9040	ACAGAUGACCAGCUUGAAGuu	CUUCAAGCUGGUCAUCUGU	-2.1	-2.2	1.6	2	3	2	-38	60.2	9.7	5	Ib	47.4	53	77	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0338	NM_003969	Huesken	UBE2M	9040	GUCGUCUGGAUCUGAGAAGcu	CUUCUCAGAUCCAGACGAC	-2.1	-2.2	1.1	1	0	2	-39.1	53.8	-2.4	4	II	52.6	43.2	65.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0339	NM_003969	Huesken	UBE2M	9040	GUCUGGAUCUGAGAAGCUGau	CAGCUUCUCAGAUCCAGAC	-2.1	-2.2	1.1	1	1	2	-39.7	47.5	0	3	II	52.6	44.7	79.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0340	NM_003969	Huesken	UBE2M	9040	GAUCUGAGAAGCUGAUAUCac	GAUAUCAGCUUCUCAGAUC	-2.4	-2.4	0.9	0	1	2	-35.9	65.3	5.1	5	II	42.1	49.4	60.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0341	NM_003969	Huesken	UBE2M	9040	UCUGAGAAGCUGAUAUCACac	GUGAUAUCAGCUUCUCAGA	-2.2	-2.4	0.9	1	4	2	-36.7	60.4	9.8	6	Ib	42.1	63.4	70.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0342	NM_003969	Huesken	UBE2M	9040	GUCUUGGGCAGGUUCAGCUcg	AGCUGAACCUGCCCAAGAC	-2.1	-2.2	-0.5	1	1	4	-42.4	61.1	-1.6	4	III	57.9	47.2	71.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0343	NM_003969	Huesken	UBE2M	9040	CUUGGGCAGGUUCAGCUCGuu	CGAGCUGAACCUGCCCAAG	-2.4	-2.1	-0.5	0	1	4	-42.6	43.2	3.4	2	II	63.2	51.8	71.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0344	NM_003969	Huesken	UBE2M	9040	UUGGGCAGGUUCAGCUCGUuu	ACGAGCUGAACCUGCCCAA	-2.2	-0.9	-0.5	0	2	4	-42.7	42.3	-8.9	4	II	57.9	57.6	66	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0345	NM_003969	Huesken	UBE2M	9040	CGUUUAUGUCCUUCUGGAUcc	AUCCAGAAGGACAUAAACG	-1.1	-2.4	-1.9	0	-2	2	-35.2	71	-5.3	3	II	42.1	34.8	56.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0346	NM_003969	Huesken	UBE2M	9040	GAUCCGCAGCUGCGCCGCCga	GGCGGCGCAGCUGCGGAUC	-3.3	-2.4	-6.3	1	3	8	-48.4	24.7	9.8	0	II	78.9	38.7	71.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0347	NM_003969	Huesken	UBE2M	9040	AUCCGCAGCUGCGCCGCCGac	CGGCGGCGCAGCUGCGGAU	-2.4	-1.1	-6.3	3	4	9	-48.4	33.5	-2.4	2	II	78.9	54.9	69.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0348	NM_003969	Huesken	UBE2M	9040	AGCUGCGCCGCCGACGCCUuc	AGGCGUCGGCGGCGCAGCU	-2.1	-2.1	-6.1	2	1	9	-49.5	27.6	-8.7	2	II	78.9	43.7	51.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0349	NM_003969	Huesken	UBE2M	9040	CCGACGCCUUCUUGCUGCUgc	AGCAGCAAGAAGGCGUCGG	-2.1	-3.3	-1.3	-2	-2	4	-43	41.9	-5.3	-1	III	63.2	30.2	53	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0350	NM_003969	Huesken	UBE2M	9040	GACGCCUUCUUGCUGCUGCcc	GCAGCAGCAAGAAGGCGUC	-3.4	-2.4	-1.3	2	2	4	-42.8	60.3	12.1	1	II	63.2	48.4	61	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0351	NM_003969	Huesken	UBE2M	9040	CGCCUUCUUGCUGCUGCCCuu	GGGCAGCAGCAAGAAGGCG	-3.3	-2.4	-1.3	0	0	4	-44.8	45.7	6.1	-1	II	68.4	42.9	58.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0352	NM_003969	Huesken	UBE2M	9040	GCUGCCCUUGGUGCCGCCCgc	GGGCGGCACCAAGGGCAGC	-3.3	-3.4	-2	0	2	7	-49.4	36.4	10.4	-1	II	78.9	38.2	64.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0353	NM_003969	Huesken	UBE2M	9040	UUGGUGCCGCCCGCCGACUcc	AGUCGGCGGGCGGCACCAA	-2.1	-0.9	-4.1	1	1	11	-47.9	36.2	-8.7	3	II	73.7	56.2	73.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0354	NM_003969	Huesken	UBE2M	9040	UGGUGCCGCCCGCCGACUCcu	GAGUCGGCGGGCGGCACCA	-2.4	-2.1	-4.1	1	2	11	-49.4	39.2	7.5	2	II	78.9	51.5	53	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0355	NM_003969	Huesken	UBE2M	9040	UGCCGCCCGCCGACUCCUCcu	GAGGAGUCGGCGGGCGGCA	-2.4	-2.1	-4.1	2	2	11	-49.6	31.2	2.5	1	II	78.9	48.6	59.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0356	NM_003969	Huesken	UBE2M	9040	CCCGCCGACUCCUCCUCCUuc	AGGAGGAGGAGUCGGCGGG	-2.1	-3.3	1.3	0	-2	7	-48.2	35	-10.7	0	III	73.7	33	41.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0357	NM_003969	Huesken	UBE2M	9040	GACUCCUCCUCCUUCUUCUgc	AGAAGAAGGAGGAGGAGUC	-2.1	-2.4	3	2	0	2	-40.9	75.3	-6.3	4	III	52.6	44.7	59.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0358	XM_371822	Huesken	C6orf110	55362	ACUGGAAGUCUGUGUCCGUga	ACGGACACAGACUUCCAGU	-2.2	-2.2	-2.3	0	2	3	-40.7	42	-4	3	II	52.6	43.8	85.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0359	XM_371822	Huesken	C6orf110	55362	GUCUGUGUCCGUGAGGGCGuc	CGCCCUCACGGACACAGAC	-2.4	-2.2	-0.5	1	2	5	-44.6	47.7	3	2	II	68.4	46.3	59.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0360	XM_371822	Huesken	C6orf110	55362	CUCAUCUUGGGAUGAGGAUga	AUCCUCAUCCCAAGAUGAG	-1.1	-2.1	-5.8	0	-2	3	-38.7	59.6	-6	3	II	47.4	37.1	53.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0361	XM_371822	Huesken	C6orf110	55362	GGGGCUCAUCCCCUGAGCUcc	AGCUCAGGGGAUGAGCCCC	-2.1	-3.3	-6.5	0	0	5	-47.5	38.9	-3.9	-2	III	68.4	32	43	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0362	XM_371822	Huesken	C6orf110	55362	CCUGAGCUCCCAGGAGCCCca	GGGCUCCUGGGAGCUCAGG	-3.3	-3.3	-10.5	-1	1	4	-48.5	20.1	5.8	0	II	73.7	37.3	36.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0363	XM_371822	Huesken	C6orf110	55362	CUCCCAGGAGCCCCAUCCCca	GGGAUGGGGCUCCUGGGAG	-3.3	-2.1	-2.9	0	1	5	-48.6	34.6	3.1	0	II	73.7	44.9	43.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0364	XM_371822	Huesken	C6orf110	55362	CAUCCCCGUCCACCUCUGAgu	UCAGAGGUGGACGGGGAUG	-2.4	-2.1	1.5	0	-2	5	-44.5	43	-5.7	2	III	63.2	31.4	29.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0365	XM_371822	Huesken	C6orf110	55362	UCUGAGUCCUGCAGCACCUga	AGGUGCUGCAGGACUCAGA	-2.1	-2.4	-0.1	1	2	2	-43.9	49.4	-6.2	5	II	57.9	58.4	61.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0366	XM_371822	Huesken	C6orf110	55362	AUUUCGCAGAUUUGGGGACag	GUCCCCAAAUCUGCGAAAU	-2.2	-1.1	2.3	1	4	4	-37.2	68.5	10.4	6	Ib	47.4	55	82	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0367	XM_371822	Huesken	C6orf110	55362	UUGCUUCUGGGGUCCACAGua	CUGUGGACCCCAGAAGCAA	-2.1	-0.9	-0.4	2	3	4	-42.3	65.2	0	4	Ib	57.9	63.6	75.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0368	XM_371822	Huesken	C6orf110	55362	UCUUGUAGUUGUGGGCACUga	AGUGCCCACAACUACAAGA	-2.1	-2.4	0	-1	1	4	-39	62.7	-1	6	II	47.4	54.7	81.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0369	XM_371822	Huesken	C6orf110	55362	CACUGAGGUAUUUGAAGUGuc	CACUUCAAAUACCUCAGUG	-2.1	-2.1	0.1	-2	0	2	-34.5	59.8	1	4	II	42.1	47	55	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0370	XM_371822	Huesken	C6orf110	55362	CAGACGUGGCAGAGACAGAug	UCUGUCUCUGCCACGUCUG	-2.4	-2.1	1.9	0	-3	3	-42.1	38.8	-6	2	III	57.9	35.7	68.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0371	XM_371822	Huesken	C6orf110	55362	ACAUAGACGUGGGAGCUAGga	CUAGCUCCCACGUCUAUGU	-2.1	-2.2	1.6	2	2	3	-40.1	48.8	2.7	7	Ia	52.6	49.8	66.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0372	XM_371822	Huesken	C6orf110	55362	AUAGACGUGGGAGCUAGGAac	UCCUAGCUCCCACGUCUAU	-2.4	-1.1	1.6	2	2	3	-41.5	45.5	-1.1	6	II	52.6	49.9	79.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0373	XM_371822	Huesken	C6orf110	55362	ACGUGGGAGCUAGGAACCCcg	GGGUUCCUAGCUCCCACGU	-3.3	-2.2	-3.4	1	3	3	-44.3	27.3	7.4	2	II	63.2	51.2	57.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0374	XM_371822	Huesken	C6orf110	55362	CAGAAGAGGCAGAGGAUGGgc	CCAUCCUCUGCCUCUUCUG	-3.3	-2.1	2.5	-1	0	3	-41.7	43.4	0.4	4	II	57.9	49.3	53.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0375	XM_371822	Huesken	C6orf110	55362	CUUCUUGUCCAGCUUGGCCgg	GGCCAAGCUGGACAAGAAG	-3.3	-2.1	-0.8	1	3	4	-41.1	67.4	12.4	3	II	57.9	57.4	65	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0376	XM_371822	Huesken	C6orf110	55362	UGUCCAGCUUGGCCGGCAGgu	CUGCCGGCCAAGCUGGACA	-2.1	-2.1	-5.8	1	3	7	-46	46.8	2.4	3	II	68.4	48.6	65.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0377	XM_371822	Huesken	C6orf110	55362	CUACCAGGUGCUUCAGCAGca	CUGCUGAAGCACCUGGUAG	-2.1	-2.1	-2	0	1	2	-41.3	48.1	-1.3	1	II	57.9	44.5	75	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0378	XM_371822	Huesken	C6orf110	55362	UACCAGGUGCUUCAGCAGCau	GCUGCUGAAGCACCUGGUA	-3.4	-1.3	-3	2	3	2	-42.6	55.5	15.5	4	II	57.9	67	82.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0379	XM_371822	Huesken	C6orf110	55362	AUGACCACCGUGAAGACGCac	GCGUCUUCACGGUGGUCAU	-3.4	-1.1	-0.6	2	4	3	-41.2	57.5	4.8	4	Ib	57.9	69.3	75.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0380	XM_371822	Huesken	C6orf110	55362	GCGUAGGCUGCGCCAAACUgg	AGUUUGGCGCAGCCUACGC	-2.1	-3.4	-2.2	0	-2	5	-43	35	-1.2	1	III	63.2	34.5	60.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0381	XM_371822	Huesken	C6orf110	55362	UGAUGCCGCUUCACGUUGCgc	GCAACGUGAAGCGGCAUCA	-3.4	-2.1	-1	1	3	5	-40.9	58.4	2.5	4	II	57.9	61.2	72.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0382	XM_371822	Huesken	C6orf110	55362	GCUUCACGUUGCGCCUCUCgg	GAGAGGCGCAACGUGAAGC	-2.4	-3.4	0.2	0	1	5	-42.2	43.3	5.1	1	II	63.2	32	56.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0383	XM_371822	Huesken	C6orf110	55362	UUGCGCCUCUCGGCGGCCGag	CGGCCGCCGAGAGGCGCAA	-2.4	-0.9	-8.4	2	4	9	-48.4	37.2	-2.4	2	II	78.9	58.6	72.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0384	XM_371822	Huesken	C6orf110	55362	GGAUCAUGUACAUGAGCAGgc	CUGCUCAUGUACAUGAUCC	-2.1	-3.3	-1.4	0	1	2	-37.6	54.5	-2.4	3	II	47.4	38.7	49	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0385	XM_371822	Huesken	C6orf110	55362	UCAUGUACAUGAGCAGGCCug	GGCCUGCUCAUGUACAUGA	-3.3	-2.4	-0.8	0	4	4	-40.8	57.9	7.4	6	Ia	52.6	65.3	71.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0386	XM_371822	Huesken	C6orf110	55362	AGCAGGUCCAUGGCGUUGCcg	GCAACGCCAUGGACCUGCU	-3.4	-2.1	-0.5	3	2	4	-43.9	52.8	7.4	5	II	63.2	58.4	71.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0387	XM_371822	Huesken	C6orf110	55362	UCCAUGGCGUUGCCGAUAAag	UUAUCGGCAACGCCAUGGA	-0.9	-2.4	-3	1	-2	4	-40.1	54.1	-1.4	6	II	52.6	44.9	62.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0388	XM_371822	Huesken	C6orf110	55362	GAAAGUGUAGCACUUGUGCau	GCACAAGUGCUACACUUUC	-3.4	-2.4	-2.6	0	3	2	-36.7	66.4	9.8	4	II	47.4	55.4	83.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0389	XM_371822	Huesken	C6orf110	55362	AAAGUGUAGCACUUGUGCAug	UGCACAAGUGCUACACUUU	-2.1	-0.9	-2.6	3	3	2	-36.4	71.4	-1.5	5	II	42.1	59.2	99.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0390	XM_371822	Huesken	C6orf110	55362	GGAGGGCCGAGAAGCACCAca	UGGUGCUUCUCGGCCCUCC	-2.1	-3.3	-1.3	0	-1	6	-46.5	18.7	-6.3	0	III	68.4	30.4	65.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0391	XM_371822	Huesken	C6orf110	55362	GGUGGGGAAGAACUGGGUGau	CACCCAGUUCUUCCCCACC	-2.1	-3.3	2.3	0	2	4	-43.5	37	7	1	II	63.2	37.4	56.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0392	XM_371822	Huesken	C6orf110	55362	UCCAUGGUGGUGAUGAUGAug	UCAUCAUCACCACCAUGGA	-2.4	-2.4	-1.1	1	0	2	-39.8	62	-4	6	II	47.4	56.3	79.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0393	XM_371822	Huesken	C6orf110	55362	CCAUGGUGGUGAUGAUGAUgg	AUCAUCAUCACCACCAUGG	-1.1	-3.3	0	0	-2	2	-38.5	44.5	-6	3	III	47.4	27.7	59.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0394	XM_371822	Huesken	C6orf110	55362	AUGAUGAUGGCUGGAGUGGug	CCACUCCAGCCAUCAUCAU	-3.3	-1.1	4.6	1	3	3	-40.7	56.1	0.7	7	Ia	52.6	60.2	77.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0395	XM_371822	Huesken	C6orf110	55362	GAUGAUGGCUGGAGUGGUGag	CACCACUCCAGCCAUCAUC	-2.1	-2.4		0	2	3	-41.8	42.5	0.1	3	II	57.9	40	70.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0396	XM_371822	Huesken	C6orf110	55362	UGGUGAGGAAGAAGAGGAGga	CUCCUCUUCUUCCUCACCA	-2.1	-2.1		-1	2	2	-40.6	44.9	-2.6	6	II	52.6	50.1	68	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0397	XM_371822	Huesken	C6orf110	55362	AGGAGGAUGAAGAGGACGAca	UCGUCCUCUUCAUCCUCCU	-2.4	-2.1	4.5	1	0	2	-41.4	44.9	-4	5	II	52.6	46.7	55.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0398	XM_371822	Huesken	C6orf110	55362	AGAUGAAGCCUCGGAUGGAga	UCCAUCCGAGGCUUCAUCU	-2.4	-2.1	0.1	1	1	3	-41.3	35.8	-6.1	5	II	52.6	38.5	65.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0399	XM_371822	Huesken	C6orf110	55362	GGCGUGGCUCCCCACGGCAgg	UGCCGUGGGGAGCCACGCC	-2.1	-3.3	-8	0	-2	4	-50	19.5	-6.1	0	III	78.9	27.3	62.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0400	XM_371822	Huesken	C6orf110	55362	AUUUACACACGUUGAAGUCcu	GACUUCAACGUGUGUAAAU	-2.4	-1.1	0.8	0	4	2	-32.6	80.3	13.1	7	Ia	36.8	61.5	101.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0401	XM_371822	Huesken	C6orf110	55362	CACGUUGAAGUCCUUCAGGau	CCUGAAGGACUUCAACGUG	-3.3	-2.1	-1.4	-1	1	2	-38.1	58.7	0.4	2	II	52.6	53	84.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0402	XM_371822	Huesken	C6orf110	55362	AUAGUCUCAUUGUGGAAGGug	CCUUCCACAAUGAGACUAU	-3.3	-1.1	1.1	1	4	2	-36.1	70.7	0	6	Ia	42.1	65	72.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0403	XM_371822	Huesken	C6orf110	55362	UUGUGGAAGGUGACAAAGGcc	CCUUUGUCACCUUCCACAA	-3.3	-0.9	0.6	1	3	2	-37.5	59	-2.6	6	Ib	47.4	72.8	74.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0404	XM_371822	Huesken	C6orf110	55362	UCAAUGGCCUCCACCUGCUca	AGCAGGUGGAGGCCAUUGA	-2.1	-2.4	-2.4	1	2	4	-43.7	52.8	-11.3	5	II	57.9	60.6	77.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0405	XM_371822	Huesken	C6orf110	55362	CCACCUGCUCACAGCCUCGca	CGAGGCUGUGAGCAGGUGG	-2.4	-3.3	-2.3	-1	0	3	-45.1	37.6	-4.6	1	II	68.4	46.2	42.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0406	XM_371822	Huesken	C6orf110	55362	UGAUCAUGGUAGGCACGUUcu	AACGUGCCUACCAUGAUCA	-0.9	-2.1	-1.6	2	1	3	-38.7	58.5	-1.7	5	II	47.4	50.5	80.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0407	XM_371822	Huesken	C6orf110	55362	GGAGGUUUGUGAAGUACAGcu	CUGUACUUCACAAACCUCC	-2.1	-3.3	0.6	1	1	2	-36.8	48.8	-2.6	2	II	47.4	39.5	57.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0408	XM_371822	Huesken	C6orf110	55362	CUCGGCCUUCUUCCUCUCUgc	AGAGAGGAAGAAGGCCGAG	-2.1	-2.1	-0.6	-1	-2	5	-42.1	53.5	-0.6	1	III	57.9	41.6	49.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0409	XM_371822	Huesken	C6orf110	55362	CUUCUUCCUCUCUGCAUCGag	CGAUGCAGAGAGGAAGAAG	-2.4	-2.1		-1	1	2	-38.7	62.7	-4.4	4	II	52.6	55.2	56.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0410	XM_371822	Huesken	C6orf110	55362	AUCGAGGAACAUUAGGCGAgc	UCGCCUAAUGUUCCUCGAU	-2.4	-1.1	1.3	1	1	4	-38.2	56.1	4.3	5	II	47.4	49.8	77.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0411	XM_371822	Huesken	C6orf110	55362	CGAGCCACGUUGUAACACGgg	CGUGUUACAACGUGGCUCG	-2.4	-2.4	-1.7	0	0	3	-38.8	46.1	-2	0	II	57.9	49	91.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0412	XM_371822	Huesken	C6orf110	55362	AGCCACGUUGUAACACGGGcg	CCCGUGUUACAACGUGGCU	-3.3	-2.1	-2.4	2	3	4	-40.6	40.8	0.1	2	II	57.9	52.2	75.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0413	XM_371822	Huesken	C6orf110	55362	UGUGCAGUUGGGGUAGGCUuc	AGCCUACCCCAACUGCACA	-2.1	-2.1	0.5	0	3	4	-43.5	52.2	-1.6	4	II	57.9	53	70.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0414	XM_371822	Huesken	C6orf110	55362	CAAAAUGCUUCUUGAUCUUuu	AAGAUCAAGAAGCAUUUUG	-0.9	-2.1	0.3	-2	-1	2	-30.8	70.1	-2.6	5	II	31.6	45.9	61.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0415	XM_371822	Huesken	C6orf110	55362	GCAUAUUUGGAGAUUCCAUug	AUGGAAUCUCCAAAUAUGC	-1.1	-3.4	-2.5	2	0	2	-34	69.5	0.8	3	II	36.8	41	78.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0416	XM_371822	Huesken	C6orf110	55362	GAUCAUCCUCCUUGUAGCGca	CGCUACAAGGAGGAUGAUC	-2.4	-2.4	1.2	0	3	3	-39.1	58.9	3.4	3	II	52.6	45.6	79.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0417	XM_371822	Huesken	C6orf110	55362	UGGAGGUGUGUCUACGCAUgc	AUGCGUAGACACACCUCCA	-1.1	-2.1	1.1	1	0	3	-41	54.2	-6.3	5	II	52.6	56.6	76.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0418	XM_371822	Huesken	C6orf110	55362	GACGGUGAGCAGCAGAUACag	GUAUCUGCUGCUCACCGUC	-2.2	-2.4	0.6	1	0	3	-41.3	47.5	12.1	2	II	57.9	42.3	65.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0419	XM_371822	Huesken	C6orf110	55362	GUUGUUCCCUGAUUUCAAGuu	CUUGAAAUCAGGGAACAAC	-2.1	-2.2	-2.6	1	2	3	-34.3	74.5	2.3	2	II	42.1	46.2	71.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0420	XM_371822	Huesken	C6orf110	55362	AUGGUGGUUCUCCCAAAGCug	GCUUUGGGAGAACCACCAU	-3.4	-1.1	-2.5	1	3	3	-40.1	57	7.5	4	II	52.6	65.5	75.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0421	XM_371822	Huesken	C6orf110	55362	GUUCUCCCAAAGCUGUAGGca	CCUACAGCUUUGGGAGAAC	-3.3	-2.2	-2.3	1	3	3	-39.1	68.4	7	3	II	52.6	48.1	81.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0422	XM_371822	Huesken	C6orf110	55362	GCACGAUGCCUACGGAGAGga	CUCUCCGUAGGCAUCGUGC	-2.1	-3.4	0.4	2	1	3	-42.7	27.4	2.4	1	II	63.2	31.9	75.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0423	XM_371822	Huesken	C6orf110	55362	CAGCAGCCCGAUGAUGUGCcg	GCACAUCAUCGGGCUGCUG	-3.4	-2.1	-0.3	1	0	5	-43.1	44.6	13.4	2	II	63.2	47.2	69.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0424	XM_371822	Huesken	C6orf110	55362	AAGGACAGGUAGUGCACGGca	CCGUGCACUACCUGUCCUU	-3.3	-0.9	1	1	4	3	-41.7	48.5	5	4	Ib	57.9	56.6	86.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0425	XM_371822	Huesken	C6orf110	55362	GUCCCGGAUCUCAUCAUCCuu	GGAUGAUGAGAUCCGGGAC	-3.3	-2.2	-3.8	1	2	5	-41.8	52.3	4.8	1	II	57.9	54.8	89.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0426	XM_371822	Huesken	C6orf110	55362	CGGAUCUCAUCAUCCUUUAuc	UAAAGGAUGAUGAGAUCCG	-1.3	-2.4	-4	0	-5	3	-35.8	67.5	-8.1	3	III	42.1	36.8	24.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0427	XM_371822	Huesken	C6orf110	55362	UGUCCCUUUGGUCAAAGUCaa	GACUUUGACCAAAGGGACA	-2.4	-2.1	-1.3	2	3	3	-37.8	76.3	12.8	4	II	47.4	65.1	89.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0428	XM_371822	Huesken	C6orf110	55362	UUGGUCAAAGUCAACGGAGcu	CUCCGUUGACUUUGACCAA	-2.1	-0.9	0.1	0	3	3	-36.9	60.8	-4.9	6	Ib	47.4	69.6	98.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0429	XM_371822	Huesken	C6orf110	55362	AGUCAACGGAGCUGGAGACag	GUCUCCAGCUCCGUUGACU	-2.2	-2.1	-1.1	2	3	3	-42.1	45.7	7.8	3	Ib	57.9	42.7	69.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0430	XM_371822	Huesken	C6orf110	55362	CUGGAGACAGAGGUGAGACgc	GUCUCACCUCUGUCUCCAG	-2.2	-2.1	0.3	-1	1	2	-42	46.4	12.7	2	II	57.9	48.5	88.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0431	XM_371822	Huesken	C6orf110	55362	UGAGACGCUCAUACCGGUCau	GACCGGUAUGAGCGUCUCA	-2.4	-2.1	-0.7	0	3	4	-41.8	55.6	12.8	5	II	57.9	63.8	99	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0432	XM_371822	Huesken	C6orf110	55362	UCAUACCGGUCAUGGCUGUcc	ACAGCCAUGACCGGUAUGA	-2.2	-2.4	-2.4	0	1	4	-41.1	51.5	-3.6	6	II	52.6	46.8	56.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0433	XM_371822	Huesken	C6orf110	55362	GGCUGUCCCCGUGCAUAGCug	GCUAUGCACGGGGACAGCC	-3.4	-3.3	0.1	1	0	5	-45.5	44.2	10.4	0	II	68.4	33.5	73.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0434	XM_371822	Huesken	C6orf110	55362	GGAAGUCUGUGUCCGUGAGgg	CUCACGGACACAGACUUCC	-2.1	-3.3	-0.6	1	1	3	-40.9	52.6	5.4	1	II	57.9	32.7	61.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0435	XM_371822	Huesken	C6orf110	55362	GUGAGGGCGUCGGGUGGCAuc	UGCCACCCGACGCCCUCAC	-2.1	-2.2	0.5	0	-1	5	-47.9	16.8	-6.1	2	III	73.7	26.6	12.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0436	XM_371822	Huesken	C6orf110	55362	CGUCGGGUGGCAUCAGCAAcu	UUGCUGAUGCCACCCGACG	-0.9	-2.4	-0.6	1	-3	4	-43.2	29.1	-8.1	1	III	63.2	25.4	39.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0437	XM_371822	Huesken	C6orf110	55362	AACUCCUCAUCUUGGGAUGag	CAUCCCAAGAUGAGGAGUU	-2.1	-0.9	-2.1	1	2	3	-38.3	75.2	0.7	4	Ib	47.4	53	53	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0438	XM_371822	Huesken	C6orf110	55362	AUCCCCUGAGCUCCCAGGAgc	UCCUGGGAGCUCAGGGGAU	-2.4	-1.1	-6.3	3	1	4	-46.5	52.1	-0.7	2	II	63.2	46.1	52	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0439	XM_371822	Huesken	C6orf110	55362	GUCCUGCAGCACCUGAGCGau	CGCUCAGGUGCUGCAGGAC	-2.4	-2.2	-1.5	2	3	3	-45.2	43.7	4.7	0	II	68.4	43.7	46.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0440	XM_371822	Huesken	C6orf110	55362	CCUGAGCGAUGUAUUUCGCag	GCGAAAUACAUCGCUCAGG	-3.4	-3.3	-4.3	-1	2	3	-38	53.4	10.9	1	II	52.6	41.8	40.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0441	XM_371822	Huesken	C6orf110	55362	AGCGAUGUAUUUCGCAGAUuu	AUCUGCGAAAUACAUCGCU	-1.1	-2.1	-4.3	0	0	3	-35.8	56.8	4.2	3	II	42.1	40.2	50.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0442	XM_371822	Huesken	C6orf110	55362	UUCUGGGGUCCACAGUAUCug	GAUACUGUGGACCCCAGAA	-2.4	-0.9	-0.9	0	2	4	-40.8	58.1	7.5	6	II	52.6	64.8	73.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0443	XM_371822	Huesken	C6orf110	55362	AGUUGUGGGCACUGAGGUAuu	UACCUCAGUGCCCACAACU	-1.3	-2.1	0.3	1	0	4	-41.4	47.8	-3.8	5	II	52.6	36.4	51.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0444	XM_371822	Huesken	C6orf110	55362	UGACGAUGGUGAUGACCAGga	CUGGUCAUCACCAUCGUCA	-2.1	-2.1	-2.3	2	3	2	-40	46.4	0	4	Ib	52.6	51.4	67	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0445	XM_371822	Huesken	C6orf110	55362	CGUGCGCAUGGUGGAAAAGaa	CUUUUCCACCAUGCGCACG	-2.1	-2.4	2.8	-2	-1	4	-39.3	38.3	1	0	II	57.9	31.1	0	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0446	XM_371822	Huesken	C6orf110	55362	GCGCAUGGUGGAAAAGAAGag	CUUCUUUUCCACCAUGCGC	-2.1	-3.4	3.1	1	-1	4	-38	36.1	0.1	2	II	52.6	36.6	39.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0447	XM_371822	Huesken	C6orf110	55362	GAGGAUGGGCGCGGCCACCac	GGUGGCCGCGCCCAUCCUC	-3.3	-2.4	-4.4	0	1	10	-49.2	21.4	7.8	1	II	78.9	42.3	49.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0448	XM_371822	Huesken	C6orf110	55362	GGAUGGGCGCGGCCACCACcu	GUGGUGGCCGCGCCCAUCC	-2.2	-3.3	-4.4	1	1	10	-49	23.9	9.8	1	II	78.9	31.9	46.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0449	XM_371822	Huesken	C6orf110	55362	GGCGCGGCCACCACCUGGUuc	ACCAGGUGGUGGCCGCGCC	-2.2	-3.3	-3.2	1	-1	9	-49.8	25.3	-11.3	0	III	78.9	31.1	57.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0450	XM_371822	Huesken	C6orf110	55362	GCAGGUAGGCGUAGUAGAGau	CUCUACUACGCCUACCUGC	-2.1	-3.4	0.9	0	1	4	-41.3	37.2	0.4	1	II	57.9	34.7	56.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0451	XM_371822	Huesken	C6orf110	55362	ACGAUGAUGGGGCAGGUGAua	UCACCUGCCCCAUCAUCGU	-2.4	-2.2	2.6	2	-1	5	-43.3	48.4	-1.4	5	II	57.9	45.1	73	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0452	XM_371822	Huesken	C6orf110	55362	GGUGAUACUGUAGGUCAUGac	CAUGACCUACAGUAUCACC	-2.1	-3.3	1.5	-1	0	2	-37.6	45.1	2.7	3	II	47.4	42.7	58.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0453	XM_371822	Huesken	C6orf110	55362	GUGAUACUGUAGGUCAUGAcc	UCAUGACCUACAGUAUCAC	-2.4	-2.2	1.5	1	-1	2	-36.7	62.4	0.9	4	II	42.1	37.1	60.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0454	XM_371822	Huesken	C6orf110	55362	ACAUCAUCCAGGCGUAGGCug	GCCUACGCCUGGAUGAUGU	-3.4	-2.2	-0.7	2	4	4	-42.3	58.8	9.8	5	Ia	57.9	55.1	72.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0455	XM_371822	Huesken	C6orf110	55362	CCGCUUCACGUUGCGCCUCuc	GAGGCGCAACGUGAAGCGG	-2.4	-3.3	-3.2	1	-1	5	-43.4	37.3	8.4	-1	II	68.4	41.4	59.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0456	XM_371822	Huesken	C6orf110	55362	CGCUUCACGUUGCGCCUCUcg	AGAGGCGCAACGUGAAGCG	-2.1	-2.4	-1.9	-1	-3	5	-42.2	43.9	-3.6	2	III	63.2	34.9	35.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0457	XM_371822	Huesken	C6orf110	55362	ACGUUGCGCCUCUCGGCGGcc	CCGCCGAGAGGCGCAACGU	-3.3	-2.2	-8.4	2	3	6	-46.1	40.5	-2.4	2	II	73.7	49.1	21.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0458	XM_371822	Huesken	C6orf110	55362	GCAGAGCCGGAUCAUGUACau	GUACAUGAUCCGGCUCUGC	-2.2	-3.4	1.5	1	0	5	-41.4	43.6	17.8	2	II	57.9	36.4	46.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0459	XM_371822	Huesken	C6orf110	55362	GAUCAUGUACAUGAGCAGGcc	CCUGCUCAUGUACAUGAUC	-3.3	-2.4	-1.4	1	2	2	-37.6	61.2	8	3	II	47.4	50.1	73.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0460	XM_371822	Huesken	C6orf110	55362	AUGUACAUGAGCAGGCCUGgg	CAGGCCUGCUCAUGUACAU	-2.1	-1.1	0	1	3	4	-40.5	58.8	-2.2	7	Ia	52.6	61.2	72.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0461	XM_371822	Huesken	C6orf110	55362	UGAGCAGGCCUGGGAUGCGca	CGCAUCCCAGGCCUGCUCA	-2.4	-2.1	-0.9	0	4	4	-46.4	31.5	0	4	II	68.4	54.6	74.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0462	XM_371822	Huesken	C6orf110	55362	GCAGCAGGUCCAUGGCGUUgc	AACGCCAUGGACCUGCUGC	-0.9	-3.4	0.7	-1	-1	4	-43.9	25.3	-6.3	1	III	63.2	24.8	27.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0463	XM_371822	Huesken	C6orf110	55362	CCAUGGCGUUGCCGAUAAAgg	UUUAUCGGCAACGCCAUGG	-0.9	-3.3	-3	-2	-4	4	-38.6	34.5	-5.7	1	III	52.6	18	36.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0464	XM_371822	Huesken	C6orf110	55362	ACCAUGAAGAUGAGGAAAGug	CUUUCCUCAUCUUCAUGGU	-2.1	-2.2	0.5	1	1	2	-35.9	56.4	-2.6	6	Ib	42.1	54.1	72.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0465	XM_371822	Huesken	C6orf110	55362	CUUGUGCAUGGUUGUCCUGuu	CAGGACAACCAUGCACAAG	-2.1	-2.1	-0.7	-2	1	2	-38.7	56.3	1	3	II	52.6	46.4	61.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0466	XM_371822	Huesken	C6orf110	55362	AUGGUUGUCCUGUUCUCCCca	GGGAGAACAGGACAACCAU	-3.3	-1.1	-0.7	2	5	3	-40.4	72.5	9.7	5	Ib	52.6	72.6	65.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0467	XM_371822	Huesken	C6orf110	55362	UUGUCCUGUUCUCCCCAGAgc	UCUGGGGAGAACAGGACAA	-2.4	-0.9	-2.5	1	0	4	-41.6	70.4	-0.7	5	II	52.6	57.4	68	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0468	XM_371822	Huesken	C6orf110	55362	CCUGUUCUCCCCAGAGCGUgu	ACGCUCUGGGGAGAACAGG	-2.2	-3.3	-2.1	-1	-1	4	-44.1	36	-13.3	0	III	63.2	32.6	48.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0469	XM_371822	Huesken	C6orf110	55362	AGCACCACAGCAGCAGGGUgg	ACCCUGCUGCUGUGGUGCU	-2.2	-2.1	-1.6	1	1	3	-45.6	40	-6.3	2	II	63.2	41.5	58.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0470	XM_371822	Huesken	C6orf110	55362	AGAACUGGGUGAUGAUGGGgu	CCCAUCAUCACCCAGUUCU	-3.3	-2.1	3.6	1	4	3	-40.5	52.4	0	5	Ib	52.6	50	68.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0471	XM_371822	Huesken	C6orf110	55362	AACUUGUCCAUGGUGGUGAug	UCACCACCAUGGACAAGUU	-2.4	-0.9	-1.1	3	1	2	-39	70.5	-1.4	7	II	47.4	56.1	67.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0472	XM_371822	Huesken	C6orf110	55362	GUGGUGAUGAUGAUGGCUGga	CAGCCAUCAUCAUCACCAC	-2.1	-2.2	4.5	1	2	3	-39.6	55.1	-0.3	4	II	52.6	55.5	74.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0473	XM_371822	Huesken	C6orf110	55362	AAGAAGAGGAGGAUGAAGAgg	UCUUCAUCCUCCUCUUCUU	-2.4	-0.9		2	1	2	-37.4	62.5	-1.3	7	II	42.1	57.3	58.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0474	XM_371822	Huesken	C6orf110	55362	UGAAGAGGACGACAUUGAUga	AUCAAUGUCGUCCUCUUCA	-1.1	-2.1	3.1	0	1	2	-36.6	56.4	-1.6	6	II	42.1	48.4	49.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0475	XM_371822	Huesken	C6orf110	55362	GACGACAUUGAUGACCAGGca	CCUGGUCAUCAAUGUCGUC	-3.3	-2.4	1.9	0	1	2	-38.8	54.3	8	3	II	52.6	50.1	60.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0476	XM_371822	Huesken	C6orf110	55362	UGAUGACCAGGCAGCGCAGcc	CUGCGCUGCCUGGUCAUCA	-2.1	-2.1	0.4	-1	3	4	-44.1	40.9	-4.9	4	Ib	63.2	49.4	66.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0477	XM_371822	Huesken	C6orf110	55362	GCAGCGCAGCCACCAGAUGaa	CAUCUGGUGGCUGCGCUGC	-2.1	-3.4	-2.2	1	0	4	-45.1	24.6	0.1	-1	II	68.4	31.4	29.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0478	XM_371822	Huesken	C6orf110	55362	CACCAGAUGAAGCCUCGGAug	UCCGAGGCUUCAUCUGGUG	-2.4	-2.1	-0.6	1	-2	3	-42.1	45.6	1.7	3	III	57.9	38.5	29.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0479	XM_371822	Huesken	C6orf110	55362	UGUGCAGGGACUCGCUGCAgg	UGCAGCGAGUCCCUGCACA	-2.1	-2.1	-4.5	0	1	3	-45.2	44.5	-0.7	4	II	63.2	46.7	25.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0480	XM_371822	Huesken	C6orf110	55362	CAGCCCUGGCAUUUACACAcg	UGUGUAAAUGCCAGGGCUG	-2.1	-2.1	-1.9	2	-2	4	-40	62.2	1.9	1	III	52.6	42	66.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0481	XM_371822	Huesken	C6orf110	55362	GCCCUGGCAUUUACACACGuu	CGUGUGUAAAUGCCAGGGC	-2.4	-3.4	-0.7	1	0	4	-40.4	42.2	0.4	1	II	57.9	41.3	52.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0482	XM_371822	Huesken	C6orf110	55362	UGUGGAAGGUGACAAAGGCca	GCCUUUGUCACCUUCCACA	-3.4	-2.1	1.5	1	4	3	-40	49.2	9.8	5	Ib	52.6	60.1	72.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0483	XM_371822	Huesken	C6orf110	55362	CCAAGAGGCUUCUCAUUCAcc	UGAAUGAGAAGCCUCUUGG	-2.1	-3.3	-1.6	0	-3	3	-38.1	48.8	-8.1	3	III	47.4	37.6	39.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0484	XM_371822	Huesken	C6orf110	55362	CAAGAGGCUUCUCAUUCACcu	GUGAAUGAGAAGCCUCUUG	-2.2	-2.1	-1.6	-1	1	3	-37	55.4	11.2	3	II	47.4	49.2	69.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0485	XM_371822	Huesken	C6orf110	55362	UCCUUCUCCCGCUUGUAGUcu	ACUACAAGCGGGAGAAGGA	-2.2	-2.4	1.2	2	1	5	-40.9	78.5	-4	6	II	52.6	56.2	72	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0486	XM_371822	Huesken	C6orf110	55362	CUCCAGCUUUGUGUAGUACuc	GUACUACACAAAGCUGGAG	-2.2	-2.1	0.7	0	0	2	-37	60.2	13.5	3	II	47.4	41.2	58.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0487	XM_371822	Huesken	C6orf110	55362	GGGGUUGAUCAUGGUAGGCac	GCCUACCAUGAUCAACCCC	-3.4	-3.3	4.7	-1	1	4	-41.9	44.8	12.7	1	II	57.9	39.8	39.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0488	XM_371822	Huesken	C6orf110	55362	UGGUAGGCACGUUCUCCUUgc	AAGGAGAACGUGCCUACCA	-0.9	-2.1	-1.6	0	0	3	-40.7	63	1.8	5	II	52.6	52.2	70.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0489	XM_371822	Huesken	C6orf110	55362	GGGUAGGCUUCCUCAAAAUgc	AUUUUGAGGAAGCCUACCC	-1.1	-3.3	-0.3	0	-3	3	-38	50.2	-6	3	III	47.4	29.7	27.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0490	XM_371822	Huesken	C6orf110	55362	GUAGGCUUCCUCAAAAUGCuu	GCAUUUUGAGGAAGCCUAC	-3.4	-2.2	-0.3	2	2	3	-36.9	59.6	2.5	4	II	47.4	59.9	87.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0491	XM_371822	Huesken	C6orf110	55362	GAUUCCAUUGAUGAAGAGGgu	CCUCUUCAUCAAUGGAAUC	-3.3	-2.4	-0.1	0	2	2	-35.1	72.9	5.3	4	II	42.1	52.1	73.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0492	XM_371822	Huesken	C6orf110	55362	CCGCUUCACCAGAUCAUCCuc	GGAUGAUCUGGUGAAGCGG	-3.3	-3.3	0.4	1	0	4	-41.1	55.9	7.4	1	II	57.9	50.6	63.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0493	XM_371822	Huesken	C6orf110	55362	UUCACCAGAUCAUCCUCCUug	AGGAGGAUGAUCUGGUGAA	-2.1	-0.9	-0.7	0	2	2	-39.8	72.7	-6.3	6	II	47.4	64.2	77.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0494	XM_371822	Huesken	C6orf110	55362	GAGCAGCAGAUACAGGAAGgc	CUUCCUGUAUCUGCUGCUC	-2.1	-2.4	0.6	2	0	2	-39.6	40.5	5.1	3	II	52.6	41.2	75.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0495	XM_371822	Huesken	C6orf110	55362	UUGUUCCCUGAUUUCAAGUug	ACUUGAAAUCAGGGAACAA	-2.2	-0.9	-3.1	0	2	3	-34.3	92.6	3.7	5	II	36.8	67.2	34.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0496	XM_371822	Huesken	C6orf110	55362	CAAGUUGGCAAUGGUGGUUcu	AACCACCAUUGCCAACUUG	-0.9	-2.1	2.6	-1	-1	3	-37.2	55.7	-0.7	5	II	47.4	44.3	34.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0497	XM_371822	Huesken	C6orf110	55362	GGCAAUGGUGGUUCUCCCAaa	UGGGAGAACCACCAUUGCC	-2.1	-3.3	-2.3	0	-2	3	-42.5	51	2	1	III	57.9	34.2	43.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0498	XM_371822	Huesken	C6orf110	55362	GAGAAGUUGACAGGCAGCAcg	UGCUGCCUGUCAACUUCUC	-2.1	-2.4	1.3	1	-1	3	-40.3	42.7	-3.4	5	II	52.6	41.6	60.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0499	XM_371822	Huesken	C6orf110	55362	AGAGGACGCCCACAACCACca	GUGGUUGUGGGCGUCCUCU	-2.2	-2.1	-0.1	2	3	5	-44	29.9	7.5	2	II	63.2	44.8	53.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0500	XM_371822	Huesken	C6orf110	55362	GAUGUGCCGCUGAAAGGACag	GUCCUUUCAGCGGCACAUC	-2.2	-2.4	-1	1	2	5	-40.8	39.7	4.8	1	II	57.9	41.1	65.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0501	XM_371822	Huesken	C6orf110	55362	ACCAUUGUCCCUUUGGUCAaa	UGACCAAAGGGACAAUGGU	-2.1	-2.2	-1.4	2	0	3	-38.9	75.9	-0.8	5	II	47.4	51	70.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0502	XM_371822	Huesken	C6orf110	55362	GUCAAAGUCAACGGAGCUGga	CAGCUCCGUUGACUUUGAC	-2.1	-2.2	-0.6	0	1	3	-38.2	47.4	2.7	5	II	52.6	44.1	84.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0503	NM_015213	Huesken	RAB6IP1	23258	CAGCACACGAAUCAAGGAAuu	UUCCUUGAUUCGUGUGCUG	-0.9	-2.1	2.8	1	-3	2	-37.1	52.6	4.7	4	III	47.4	36.4	22.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0504	NM_015213	Huesken	RAB6IP1	23258	AGCCAGCAGGGCAAUCCAGug	CUGGAUUGCCCUGCUGGCU	-2.1	-2.1	-3.1	3	2	4	-44.6	33	-2.2	1	II	63.2	42.6	63.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0505	NM_015213	Huesken	RAB6IP1	23258	UAAUGUCUCAUAAUAGGUUug	AACCUAUUAUGAGACAUUA	-0.9	-1.3	1.3	1	3	2	-30.8	84.3	-4.2	7	II	26.3	69.6	66.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0506	NM_015213	Huesken	RAB6IP1	23258	CUCCACAGAGCAACAGCGUca	ACGCUGUUGCUCUGUGGAG	-2.2	-2.1	-1.3	0	-1	3	-41.6	37.2	-8.2	1	III	57.9	41.1	60.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0507	NM_015213	Huesken	RAB6IP1	23258	CUCAGGCUUAUGGAAGUGCuu	GCACUUCCAUAAGCCUGAG	-3.4	-2.1	0.8	-1	0	3	-39.3	51.1	5.4	4	II	52.6	52.4	78.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0508	NM_015213	Huesken	RAB6IP1	23258	GCUGGGAUGUGAGCAGCUCcc	GAGCUGCUCACAUCCCAGC	-2.4	-3.4	-2.1	1	1	3	-44.1	31.2	7.4	0	II	63.2	37.1	42.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0509	NM_015213	Huesken	RAB6IP1	23258	CACAUACUCCACCAGCCAUuu	AUGGCUGGUGGAGUAUGUG	-1.1	-2.1	-0.3	0	-2	3	-40.5	55	-3.6	3	II	52.6	36.2	71.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0510	NM_015213	Huesken	RAB6IP1	23258	GUAAGCUUCCCCAAGUUCUgg	AGAACUUGGGGAAGCUUAC	-2.1	-2.2	-1.1	2	0	4	-37.9	64.3	-11.3	4	II	47.4	52.7	88.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0511	NM_015213	Huesken	RAB6IP1	23258	CUUCCCCAAGUUCUGGCACuc	GUGCCAGAACUUGGGGAAG	-2.2	-2.1	-1.3	0	2	4	-41.1	58.7	13.2	0	II	57.9	44.5	41.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0512	NM_015213	Huesken	RAB6IP1	23258	UGUCUCACCCAAUUCUCCUga	AGGAGAAUUGGGUGAGACA	-2.1	-2.1	1.7	2	3	3	-39.4	76.9	0.7	6	II	47.4	64.6	70.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0513	NM_015213	Huesken	RAB6IP1	23258	UCUUGCUUGGUACGAUCAGaa	CUGAUCGUACCAAGCAAGA	-2.1	-2.4	0.6	1	3	2	-37.5	61.7	2.4	6	Ib	47.4	56.3	54.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0514	NM_015213	Huesken	RAB6IP1	23258	UAAUCGACGGCAUUGAAAGac	CUUUCAAUGCCGUCGAUUA	-2.1	-1.3	2.2	1	4	4	-34.3	78.1	0	7	Ia	42.1	70.9	76.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0515	NM_015213	Huesken	RAB6IP1	23258	CGACGGCAUUGAAAGACAGga	CUGUCUUUCAAUGCCGUCG	-2.1	-2.4	1.6	0	0	4	-37.4	36	-4.6	1	II	52.6	38.3	47.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0516	NM_015213	Huesken	RAB6IP1	23258	UCCCCGAUGUUCUGGAUGUgc	ACAUCCAGAACAUCGGGGA	-2.2	-2.4	-1.3	1	0	5	-41.1	55.6	-6.3	4	II	52.6	50.9	44.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0517	NM_015213	Huesken	RAB6IP1	23258	GAAUCAGGGAGAUCCUCAGgg	CUGAGGAUCUCCCUGAUUC	-2.1	-2.4	-2.9	1	2	3	-40	57.7	0	4	II	52.6	45.1	60.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0518	NM_015213	Huesken	RAB6IP1	23258	GGGACCAUAAGGCUGAUUUcc	AAAUCAGCCUUAUGGUCCC	-0.9	-3.3	-2.1	0	-2	3	-38.2	69.5	0.8	3	III	47.4	39.2	41.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0519	NM_015213	Huesken	RAB6IP1	23258	ACCAUAAGGCUGAUUUCCCcu	GGGAAAUCAGCCUUAUGGU	-3.3	-2.2	-2	2	4	3	-38.2	62.1	7.1	4	Ia	47.4	60.5	61.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0520	NM_015213	Huesken	RAB6IP1	23258	UUAUUGCGGCAUUCCUUCAgc	UGAAGGAAUGCCGCAAUAA	-2.1	-0.9	-0.9	1	1	5	-36.1	80.7	1.6	8	II	42.1	63.2	77.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0521	NM_015213	Huesken	RAB6IP1	23258	ACAGUUUGGGCUGGCGGAUag	AUCCGCCAGCCCAAACUGU	-1.1	-2.2	-0.8	2	1	5	-42.6	41.4	-3.3	4	II	57.9	41.3	40.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0522	NM_015213	Huesken	RAB6IP1	23258	UGGAUGUACUUCUCCCUCUgg	AGAGGGAGAAGUACAUCCA	-2.1	-2.1	-2.9	2	0	3	-39.8	72.6	-6.3	6	II	47.4	66.3	80.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0523	NM_015213	Huesken	RAB6IP1	23258	CACUUGUUGCUGGCUGGCCca	GGCCAGCCAGCAACAAGUG	-3.3	-2.1	-1.8	1	1	4	-43.1	52.7	5.4	2	II	63.2	52	73.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0524	NM_015213	Huesken	RAB6IP1	23258	CCUUGUCCAAUCUUCAUGUca	ACAUGAAGAUUGGACAAGG	-2.2	-3.3	0.9	-1	-1	2	-35.7	73	-6	4	III	42.1	45.9	70.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0525	NM_015213	Huesken	RAB6IP1	23258	GAAUUGCAGUAUGGUCAAUuu	AUUGACCAUACUGCAAUUC	-1.1	-2.4	1.4	0	-1	2	-33.7	59.1	1.4	4	II	36.8	31.3	45.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0526	NM_015213	Huesken	RAB6IP1	23258	GAUGUACGGAGAGUAGGUGuc	CACCUACUCUCCGUACAUC	-2.1	-2.4	0.6	1	3	3	-39.2	48	2.3	4	II	52.6	41.6	54.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0527	NM_015213	Huesken	RAB6IP1	23258	GUAGGUGUCCGAACAUUCAac	UGAAUGUUCGGACACCUAC	-2.1	-2.2	0.5	1	-1	3	-37.6	53.1	-6.3	4	III	47.4	45	49	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0528	NM_015213	Huesken	RAB6IP1	23258	UUAUUUUGUUGUCAAUGAAag	UUCAUUGACAACAAAAUAA	-0.9	-0.9	0.9	1	1	1	-27.4	95.3	1.7	8	II	21.1	62	97.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0529	NM_015213	Huesken	RAB6IP1	23258	UGAAAGAUGCAAACAUCUGgg	CAGAUGUUUGCAUCUUUCA	-2.1	-2.1	-4.2	1	3	2	-33.3	68.1	2.4	6	Ia	36.8	69.2	75.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0530	NM_015213	Huesken	RAB6IP1	23258	AGAUGCAAACAUCUGGGUCuc	GACCCAGAUGUUUGCAUCU	-2.4	-2.1	-4.1	1	4	3	-38.2	70	17.5	4	Ib	47.4	56.6	71.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0531	NM_015213	Huesken	RAB6IP1	23258	CUUGAGAGGAAGGGCAGGUag	ACCUGCCCUUCCUCUCAAG	-2.2	-2.1	2	-1	0	4	-42.5	37.5	-1	4	II	57.9	43.7	53.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0532	NM_015213	Huesken	RAB6IP1	23258	GUUUUGCAUUUGCUCCCUGuu	CAGGGAGCAAAUGCAAAAC	-2.1	-2.2	-1.5	0	3	3	-36.2	63.9	4.7	3	II	47.4	48.7	67.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0533	NM_015213	Huesken	RAB6IP1	23258	UUUGCAUUUGCUCCCUGUUgg	AACAGGGAGCAAAUGCAAA	-0.9	-0.9	-1.5	1	2	3	-36.2	79.3	-0.9	5	II	42.1	63.5	49.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0534	NM_015213	Huesken	RAB6IP1	23258	UAUCCUGGCUGGGUUGGAUga	AUCCAACCCAGCCAGGAUA	-1.1	-1.3	-2	2	3	3	-41.8	63.3	-1.6	5	II	52.6	51.5	51.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0535	NM_015213	Huesken	RAB6IP1	23258	GUAAAUCCUGAGUUCUUCUuc	AGAAGAACUCAGGAUUUAC	-2.1	-2.2	0.8	0	1	2	-33.8	79.8	3.4	5	II	36.8	53.1	44.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0536	NM_015213	Huesken	RAB6IP1	23258	UUUCCAGGCUCACCCCAGUuc	ACUGGGGUGAGCCUGGAAA	-2.2	-0.9	-4.6	2	2	4	-43.5	52.6	-3.9	4	II	57.9	57	37.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0537	NM_015213	Huesken	RAB6IP1	23258	UUCCAGGCUCACCCCAGUUcu	AACUGGGGUGAGCCUGGAA	-0.9	-0.9	-4.6	1	1	4	-43.5	52.2	1.1	4	II	57.9	57.4	58.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0538	NM_015213	Huesken	RAB6IP1	23258	CAAGGCUUGCAGCCGGGCAau	UGCCCGGCUGCAAGCCUUG	-2.1	-2.1	-4.3	1	-1	7	-45.7	40	-1.1	1	III	68.4	39.8	56.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0539	NM_015213	Huesken	RAB6IP1	23258	CGUAGGAAUGCAAAGGGGAgc	UCCCCUUUGCAUUCCUACG	-2.4	-2.4	2.8	-1	-2	4	-39.5	37.1	-10.7	3	III	52.6	37.7	44.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0540	NM_015213	Huesken	RAB6IP1	23258	GGCCCGCAGCCUCUUCAGCuu	GCUGAAGAGGCUGCGGGCC	-3.4	-3.3	-3.1	2	1	7	-47.5	36.6	12.8	-2	II	73.7	31.4	37.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0541	NM_015213	Huesken	RAB6IP1	23258	UUCAGCUUGGAGGCACUCUca	AGAGUGCCUCCAAGCUGAA	-2.1	-0.9	-0.4	2	1	3	-41.4	65.5	-1.7	7	II	52.6	64.2	66.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0542	NM_015213	Huesken	RAB6IP1	23258	GUUGGGGAACUGUGGCAAGuc	CUUGCCACAGUUCCCCAAC	-2.1	-2.2	2.2	-1	1	4	-40.9	38.7	0	2	II	57.9	38.8	50.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0543	NM_015213	Huesken	RAB6IP1	23258	GGCAAGUCCUCUGGCAACUca	AGUUGCCAGAGGACUUGCC	-2.1	-3.3	0.4	1	-2	3	-42.4	43.3	-0.6	2	III	57.9	34.6	71.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0544	NM_015213	Huesken	RAB6IP1	23258	CACAAAGCAGAGGUUAGCCuc	GGCUAACCUCUGCUUUGUG	-3.3	-2.1	-1.5	-1	2	3	-38.9	56.3	12.7	3	II	52.6	52.3	70.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0545	NM_015213	Huesken	RAB6IP1	23258	CAGAGGUUAGCCUCUUGAGgc	CUCAAGAGGCUAACCUCUG	-2.1	-2.1	-5.9	0	0	3	-39.3	60.6	-6.7	2	II	52.6	47.4	52.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0546	NM_015213	Huesken	RAB6IP1	23258	AGUCAUCAGUCUCUGGUAAug	UUACCAGAGACUGAUGACU	-0.9	-2.1	0.1	3	0	2	-37.5	64.2	4.4	5	II	42.1	36.2	28.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0547	NM_015213	Huesken	RAB6IP1	23258	UGGCCCAUAGACCCCAGAAaa	UUCUGGGGUCUAUGGGCCA	-0.9	-2.1	-5.2	1	-1	5	-44	54.6	-1.4	2	II	57.9	45.7	63.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0548	NM_015213	Huesken	RAB6IP1	23258	AGGAGGUGGGAGCGGCACCuc	GGUGCCGCUCCCACCUCCU	-3.3	-2.1	-3.6	2	2	5	-48.7	34.5	12.1	2	II	73.7	52.4	39	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0549	NM_015213	Huesken	RAB6IP1	23258	UGCCUGGUGGAGUUGCUCCag	GGAGCAACUCCACCAGGCA	-3.3	-2.1	-3.8	2	3	3	-44.8	62.7	12	4	II	63.2	65.4	62.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0550	NM_015213	Huesken	RAB6IP1	23258	UCCAGCACGCUCCGACAUGcc	CAUGUCGGAGCGUGCUGGA	-2.1	-2.4	-2.4	0	1	3	-43.5	41.6	0.1	3	II	63.2	53.3	60.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0551	NM_015213	Huesken	RAB6IP1	23258	UGCACUUAGAGACGUAGAGag	CUCUACGUCUCUAAGUGCA	-2.1	-2.1	0.1	1	2	2	-37.8	69.1	2.4	6	Ib	47.4	57.9	68.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0552	NM_015213	Huesken	RAB6IP1	23258	UGUGAGGGCAAACCCAAAUgu	AUUUGGGUUUGCCCUCACA	-1.1	-2.1	-4.4	1	0	4	-38.6	58.9	3.4	6	II	47.4	56.3	72.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0553	NM_015213	Huesken	RAB6IP1	23258	UGUGAUAAUAAAGGCAUGGaa	CCAUGCCUUUAUUAUCACA	-3.3	-2.1	3.4	-1	3	3	-33.7	71	5	8	Ia	36.8	71	72.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0554	NM_015213	Huesken	RAB6IP1	23258	AAGGCAUGGAAUUGGGGCUcc	AGCCCCAAUUCCAUGCCUU	-2.1	-0.9	1.4	2	2	5	-41.1	60.4	1.4	5	II	52.6	53.3	57.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0555	NM_015213	Huesken	RAB6IP1	23258	CUGGGAUCAGCCUGGGUCUug	AGACCCAGGCUGAUCCCAG	-2.1	-2.1	-0.5	-1	-2	3	-45.1	41.6	-10.7	2	III	63.2	41.8	75.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0556	NM_015213	Huesken	RAB6IP1	23258	CCUACUGCAUCUUGGUCAAag	UUGACCAAGAUGCAGUAGG	-0.9	-3.3	1.3	-2	-3	2	-38.1	58.4	-5.1	3	III	47.4	26.4	57.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0557	NM_015213	Huesken	RAB6IP1	23258	AAAAUUUUCUCCUUCAGUCgu	GACUGAAGGAGAAAAUUUU	-2.4	-0.9	1.2	3	5	2	-30.9	96.7	5	7	Ia	31.6	75.7	90.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0558	NM_015213	Huesken	RAB6IP1	23258	AAGGGCUGGCACCAUCCCUgg	AGGGAUGGUGCCAGCCCUU	-2.1	-0.9	-3.1	3	2	4	-45.8	45.6	-1.6	2	II	63.2	54.1	83.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0559	NM_015213	Huesken	RAB6IP1	23258	CCAUCCCUGGCUUUAGAAGcc	CUUCUAAAGCCAGGGAUGG	-2.1	-3.3	-1.1	0	0	3	-39.1	62.2	1	1	II	52.6	37.6	46.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0560	NM_015213	Huesken	RAB6IP1	23258	ACUGGCAUAAUGCCGACAGcu	CUGUCGGCAUUAUGCCAGU	-2.1	-2.2	-4.9	1	3	4	-39.6	57.1	2.4	4	II	52.6	54.7	73	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0561	NM_015213	Huesken	RAB6IP1	23258	GUGAUGUUGAACUCCUGCAau	UGCAGGAGUUCAACAUCAC	-2.1	-2.2	0.4	2	-1	2	-38.1	69.9	-3.8	5	II	47.4	49.8	62.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0562	NM_015213	Huesken	RAB6IP1	23258	AAUGUCUGCAGCACACGAAuc	UUCGUGUGCUGCAGACAUU	-0.9	-0.9	-0.4	3	1	2	-38.2	62.8	-8.7	7	II	47.4	50.7	40.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0563	NM_015213	Huesken	RAB6IP1	23258	GAGGUGAUCUCUGGCUCCCaa	GGGAGCCAGAGAUCACCUC	-3.3	-2.4	-0.6	0	2	3	-44.5	44.8	8.1	2	II	63.2	48.8	49.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0564	NM_015213	Huesken	RAB6IP1	23258	AUCGGCAGAAGUUCCGGGCuc	GCCCGGAACUUCUGCCGAU	-3.4	-1.1	-2.8	1	4	6	-43.4	58.1	10.4	3	II	63.2	61	70.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0565	NM_015213	Huesken	RAB6IP1	23258	AGUGCUUCACAAUGCCAUUga	AAUGGCAUUGUGAAGCACU	-0.9	-2.1	-1	1	0	3	-36.5	67.5	-1.7	3	II	42.1	49.1	60.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0566	NM_015213	Huesken	RAB6IP1	23258	GACUGCUGCAGCGGCGGGGuc	CCCCGCCGCUGCAGCAGUC	-3.3	-2.4	-1.5	1	2	9	-48.8	33.1	-2.4	2	II	78.9	39.2	61.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0567	NM_015213	Huesken	RAB6IP1	23258	UCCGGCAUGGCCUCUCAUCca	GAUGAGAGGCCAUGCCGGA	-2.4	-2.4	-2.9	1	1	5	-44.7	52.3	2.7	2	II	63.2	58.7	63	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0568	NM_015213	Huesken	RAB6IP1	23258	AUGGCCUCUCAUCCACCUCag	GAGGUGGAUGAGAGGCCAU	-2.4	-1.1	-2.4	2	3	4	-43.2	64	15.1	2	II	57.9	61.5	74.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0569	NM_015213	Huesken	RAB6IP1	23258	CAGCUCCCCAACUAGGAUCcg	GAUCCUAGUUGGGGAGCUG	-2.4	-2.1	-3.4	1	-1	4	-41.9	59.4	5.4	1	II	57.9	50.9	66.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0570	NM_015213	Huesken	RAB6IP1	23258	GCUUCCAUCAUCCAUGCCCuu	GGGCAUGGAUGAUGGAAGC	-3.3	-3.4	0.2	1	2	4	-41.9	62.1	7.5	3	II	57.9	52.6	54.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0571	NM_015213	Huesken	RAB6IP1	23258	UCCACCAGCCAUUUGGCAUac	AUGCCAAAUGGCUGGUGGA	-1.1	-2.4	-4.1	1	1	3	-41.2	72.3	3.7	4	II	52.6	50.9	69.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0572	NM_015213	Huesken	RAB6IP1	23258	AUCCAUGGGUUGGCAGUGAac	UCACUGCCAACCCAUGGAU	-2.4	-1.1	-1.4	3	0	3	-41.5	43.3	-1.1	5	II	52.6	44.4	57.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0573	NM_015213	Huesken	RAB6IP1	23258	AAUCGACGGCAUUGAAAGAca	UCUUUCAAUGCCGUCGAUU	-2.4	-0.9	2.2	2	1	4	-35.4	55.3	1.6	4	II	42.1	40.9	52.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0574	NM_015213	Huesken	RAB6IP1	23258	GAAAGACAGGAGGUGAUAGag	CUAUCACCUCCUGUCUUUC	-2.1	-2.4	2.6	1	2	2	-37.4	53.9	4.6	4	II	47.4	42.2	63.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0575	NM_015213	Huesken	RAB6IP1	23258	GGAUGUGCCUCAUAUCCUGaa	CAGGAUAUGAGGCACAUCC	-2.1	-3.3	-0.9	1	1	3	-39.9	52.1	-2.4	3	II	52.6	44.2	46.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0576	NM_015213	Huesken	RAB6IP1	23258	GGAGGCAUGAGUGAGCUGGca	CCAGCUCACUCAUGCCUCC	-3.3	-3.3	-0.8	1	1	3	-44	44	3	3	II	63.2	45.3	64.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0577	NM_015213	Huesken	RAB6IP1	23258	CCUACGUUCUGAAUCAAGAag	UCUUGAUUCAGAACGUAGG	-2.4	-3.3	0.5	1	-2	2	-35.3	66	-6	3	III	42.1	42.4	29.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0578	NM_015213	Huesken	RAB6IP1	23258	UUUCUCUGCCGGUUGUCCUga	AGGACAACCGGCAGAGAAA	-2.1	-0.9	-0.7	3	4	5	-40.5	79.2	-1.6	7	II	52.6	67.4	67	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0579	NM_015213	Huesken	RAB6IP1	23258	AACAGGUGGGACCAUAAGGcu	CCUUAUGGUCCCACCUGUU	-3.3	-0.9	-0.8	3	3	3	-40.2	58.9	2.4	5	Ib	52.6	62.3	62.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0580	NM_015213	Huesken	RAB6IP1	23258	GAUCCUUUCCAGGAGAUCAca	UGAUCUCCUGGAAAGGAUC	-2.1	-2.4	-5.3	3	-1	2	-38.8	66.5	-1.5	3	II	47.4	45.6	44.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0581	NM_015213	Huesken	RAB6IP1	23258	UUUCCAGGAGAUCACAAAGgc	CUUUGUGAUCUCCUGGAAA	-2.1	-0.9	0.8	1	3	2	-35.7	73.5	7.7	6	Ib	42.1	65.6	65.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0582	NM_015213	Huesken	RAB6IP1	23258	AGGAGAUCACAAAGGCUGGca	CCAGCCUUUGUGAUCUCCU	-3.3	-2.1	1.8	1	2	3	-40.3	50.6	-0.3	5	Ib	52.6	52.8	47.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0583	NM_015213	Huesken	RAB6IP1	23258	GAUCACAAAGGCUGGCAAUca	AUUGCCAGCCUUUGUGAUC	-1.1	-2.4	0.6	0	-1	3	-37.9	53	-3.6	4	II	47.4	33.7	48.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0584	NM_015213	Huesken	RAB6IP1	23258	UCUUGGUCUUAUUGCGGCAuu	UGCCGCAAUAAGACCAAGA	-2.1	-2.4	3.3	0	1	5	-38.4	67.6	1.6	6	II	47.4	53	69.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0585	NM_015213	Huesken	RAB6IP1	23258	GAUGUACUUCUCCCUCUGGuc	CCAGAGGGAGAAGUACAUC	-3.3	-2.4	-0.2	0	2	3	-39.8	58.7	0.1	4	II	52.6	46.6	34.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0586	NM_015213	Huesken	RAB6IP1	23258	CUCUGGUCAUUAUCUAAACgc	GUUUAGAUAAUGACCAGAG	-2.2	-2.1	0.5	0	-1	2	-32.9	73.4	5.4	3	II	36.8	51.6	51.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0587	NM_015213	Huesken	RAB6IP1	23258	CAGUGGAAAGUACAUCAGAcu	UCUGAUGUACUUUCCACUG	-2.4	-2.1	1.6	-1	-3	2	-36	50.4	-3.4	3	III	42.1	43.5	47.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0588	NM_015213	Huesken	RAB6IP1	23258	AUUCAACAGCCUGAUCUUGuc	CAAGAUCAGGCUGUUGAAU	-2.1	-1.1	-0.4	3	3	3	-35.7	60	3.4	6	Ia	42.1	55	55.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0589	NM_015213	Huesken	RAB6IP1	23258	GGUCUCCAGGAAUCUUGAGag	CUCAAGAUUCCUGGAGACC	-2.1	-3.3	-0.5	2	1	2	-39.6	54.2	2.3	2	II	52.6	32.6	64.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0590	NM_015213	Huesken	RAB6IP1	23258	GCUUUAUCAAAGUUUUGCAuu	UGCAAAACUUUGAUAAAGC	-2.1	-3.4	1	1	0	2	-30.6	85.3	0.9	5	II	31.6	41.8	46	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0591	NM_015213	Huesken	RAB6IP1	23258	GGAUGACAAACGCCUCAUAau	UAUGAGGCGUUUGUCAUCC	-1.3	-3.3	-1.4	0	-3	4	-37.7	47.1	-3.7	2	III	47.4	26.7	44.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0592	NM_015213	Huesken	RAB6IP1	23258	GCCUCAUAAUCUGCAAACAuc	UGUUUGCAGAUUAUGAGGC	-2.1	-3.4	1	1	-3	3	-35.9	57.4	-3.1	2	III	42.1	29.7	38.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0593	NM_015213	Huesken	RAB6IP1	23258	UGCAAACAUCUGAGUGAAAcg	UUUCACUCAGAUGUUUGCA	-0.9	-2.1	1.3	-1	-2	2	-34.4	53.5	-3.6	5	II	36.8	39.5	42.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0594	NM_015213	Huesken	RAB6IP1	23258	AACUUCCCGGAUCUGAAUGuu	CAUUCAGAUCCGGGAAGUU	-2.1	-0.9	0.3	2	3	5	-37.4	77.7	10.1	5	Ib	47.4	57.2	74.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0595	NM_015213	Huesken	RAB6IP1	23258	UUCUUCUUCAUCACACUGAac	UCAGUGUGAUGAAGAAGAA	-2.4	-0.9	-0.5	2	0	1	-34.9	86.1	-8.7	9	II	36.8	68.8	75.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0596	NM_015213	Huesken	RAB6IP1	23258	ACUUUGAGAUCCUUAUUGCug	GCAAUAAGGAUCUCAAAGU	-3.4	-2.2	2.5	1	4	2	-33.7	81.5	5	7	Ia	36.8	60.5	66.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0597	NM_015213	Huesken	RAB6IP1	23258	UCCUUAUUGCUGCUGGGGUcu	ACCCCAGCAGCAAUAAGGA	-2.2	-2.4	0.4	2	2	4	-41.4	65.5	0.8	6	II	52.6	53.3	64.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0598	NM_015213	Huesken	RAB6IP1	23258	ACGCACUUCCAACUUUUCCag	GGAAAAGUUGGAAGUGCGU	-3.3	-2.2	0.7	4	3	3	-36.7	73.5	17.1	5	II	47.4	61.6	60.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0599	NM_015213	Huesken	RAB6IP1	23258	CUUAAGAAGCUCGUAGGAAug	UUCCUACGAGCUUCUUAAG	-0.9	-2.1	1.7	0	-1	2	-35.2	51	-3.1	5	II	42.1	39.2	59.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0600	NM_015213	Huesken	RAB6IP1	23258	UUAAGAAGCUCGUAGGAAUgc	AUUCCUACGAGCUUCUUAA	-1.1	-0.9	1.4	1	1	2	-34.2	69.5	-6.3	7	II	36.8	60.9	65.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0601	NM_015213	Huesken	RAB6IP1	23258	GAAGCUCGUAGGAAUGCAAag	UUGCAUUCCUACGAGCUUC	-0.9	-2.4	0.4	0	-1	2	-37.5	51.2	-6.3	3	III	47.4	35.1	50.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0602	NM_015213	Huesken	RAB6IP1	23258	AGCCAGCAAUGUUCCCAUUcc	AAUGGGAACAUUGCUGGCU	-0.9	-2.1	-2.6	2	-1	3	-38.8	55.8	1.8	2	II	47.4	39.1	43.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0603	NM_015213	Huesken	RAB6IP1	23258	GCCAGCAAUGUUCCCAUUCcu	GAAUGGGAACAUUGCUGGC	-2.4	-3.4	-3	0	-1	3	-39.1	56.4	12.8	2	II	52.6	45.6	45.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0604	NM_015213	Huesken	RAB6IP1	23258	GCAAUGUUCCCAUUCCUCUug	AGAGGAAUGGGAACAUUGC	-2.1	-3.4	-3	2	0	3	-38.1	67.2	-4	4	II	47.4	49.2	53.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0605	NM_015213	Huesken	RAB6IP1	23258	CAAUGUUCCCAUUCCUCUUgu	AAGAGGAAUGGGAACAUUG	-0.9	-2.1	-3	1	-1	3	-35.6	79	-0.7	3	II	42.1	52.1	50	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0606	NM_015213	Huesken	RAB6IP1	23258	GCCCGCAGCCUCUUCAGCUug	AGCUGAAGAGGCUGCGGGC	-2.1	-3.4	-3	2	0	6	-46.3	37.3	-4	-1	III	68.4	35.3	54.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0607	NM_015213	Huesken	RAB6IP1	23258	CCAAUUUGUUGGGGAACUGug	CAGUUCCCCAACAAAUUGG	-2.1	-3.3	-1.1	-1	0	4	-36.1	52.9	-2	3	II	47.4	45.1	67.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0608	NM_015213	Huesken	RAB6IP1	23258	CAAUGAAGUGGUUGUCAAUgu	AUUGACAACCACUUCAUUG	-1.1	-2.1	0.6	-2	-2	2	-33.1	64.1	-3	4	II	36.8	39.3	48.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0609	NM_015213	Huesken	RAB6IP1	23258	AGCUUUGACCGGUCAUCCAgg	UGGAUGACCGGUCAAAGCU	-2.1	-2.1	-1	2	0	4	-40.7	61.6	-3.8	4	II	52.6	45.5	67.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0610	NM_015213	Huesken	RAB6IP1	23258	AUCUAAGAAAUGCAGGAGAga	UCUCCUGCAUUUCUUAGAU	-2.4	-1.1	1.2	1	0	2	-35.1	63.1	1.4	7	II	36.8	51.9	51.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0611	NM_015213	Huesken	RAB6IP1	23258	UUUGACAGGAAAGUCAAAUag	AUUUGACUUUCCUGUCAAA	-1.1	-0.9	-4.9	1	2	2	-31.9	77.3	3.4	7	II	31.6	66.6	53.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0612	NM_015213	Huesken	RAB6IP1	23258	UAUUGGCCCAUAGACCCCAga	UGGGGUCUAUGGGCCAAUA	-2.1	-1.3	-5.2	1	2	5	-41.9	54.1	-3.8	6	II	52.6	63.2	66.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0613	NM_015213	Huesken	RAB6IP1	23258	CCAGGAGGUGGGAGCGGCAcc	UGCCGCUCCCACCUCCUGG	-2.1	-3.3	-0.3	-2	-2	5	-48.6	10.4	-8.3	1	III	73.7	27.2	24.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0614	NM_015213	Huesken	RAB6IP1	23258	UGUAUAUGUAGCUCUCAAGgg	CUUGAGAGCUACAUAUACA	-2.1	-2.1	2.4	1	2	2	-34.3	87.4	-2.4	8	Ia	36.8	66.6	74.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0615	NM_015213	Huesken	RAB6IP1	23258	CAUAGGAGUUGAAGCGCUGca	CAGCGCUUCAACUCCUAUG	-2.1	-2.1	2.5	-2	1	4	-38.4	44.6	-4.6	4	II	52.6	48.3	49.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0616	NM_015213	Huesken	RAB6IP1	23258	UGCAGUUUGGUCACAGGAGug	CUCCUGUGACCAAACUGCA	-2.1	-2.1	0.6	2	2	2	-40	59.6	-4.9	5	Ib	52.6	60.5	80.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0617	NM_015213	Huesken	RAB6IP1	23258	CAGGAGUGUCUUCACCAUCcu	GAUGGUGAAGACACUCCUG	-2.4	-2.1	-1.7	0	-1	2	-39.5	52.2	13.5	2	II	52.6	54.9	82.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0618	NM_015213	Huesken	RAB6IP1	23258	ACUCAGCAUUGUGCAUGUGgu	CACAUGCACAAUGCUGAGU	-2.1	-2.2	-0.8	2	3	2	-37.8	51.6	5.7	4	II	47.4	44.6	69.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0619	NM_015213	Huesken	RAB6IP1	23258	AUUGUGCAUGUGGUAGAGGgu	CCUCUACCACAUGCACAAU	-3.3	-1.1	3.3	1	5	2	-38.1	57.4	2.3	5	Ib	47.4	61.1	68.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0620	NM_015213	Huesken	RAB6IP1	23258	GCAUUGCACUGCAGAUCUGcu	CAGAUCUGCAGUGCAAUGC	-2.1	-3.4	-1.2	0	1	2	-39.2	43.5	-4.9	2	II	52.6	34.9	56.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0621	NM_015213	Huesken	RAB6IP1	23258	CUUGCUAGUCACCUCUUCAua	UGAAGAGGUGACUAGCAAG	-2.1	-2.1	-2.5	-1	-1	2	-38.2	70	-1.1	3	II	47.4	49.6	68.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0622	NM_015213	Huesken	RAB6IP1	23258	AUGUGAGGGCAAACCCAAAug	UUUGGGUUUGCCCUCACAU	-0.9	-1.1	-4.4	2	-1	4	-38.6	47.2	-4	4	II	47.4	43.6	73.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0623	NM_015213	Huesken	RAB6IP1	23258	AUGUCCGAGAGCCAUCCUCcc	GAGGAUGGCUCUCGGACAU	-2.4	-1.1	-2.6	2	3	3	-42.6	60.3	7.5	4	II	57.9	61.2	55.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0624	NM_015213	Huesken	RAB6IP1	23258	GGCUCCCUGGGAUCAGCCUgg	AGGCUGAUCCCAGGGAGCC	-2.1	-3.3	-3.2	1	-1	3	-47.5	42.3	-4	-1	III	68.4	27.9	57.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0625	NM_015213	Huesken	RAB6IP1	23258	UGGGUCUUGAAUGCCAGCCcu	GGCUGGCAUUCAAGACCCA	-3.3	-2.1	0.8	2	3	3	-42.5	68.8	12.7	5	II	57.9	71.7	75.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0626	NM_015213	Huesken	RAB6IP1	23258	AUUUGAAUGUUCUUCUCAAug	UUGAGAAGAACAUUCAAAU	-0.9	-1.1	-0.7	2	2	1	-29.9	82.7	-3.8	6	II	26.3	52.9	54.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0627	NM_015213	Huesken	RAB6IP1	23258	CAUAAUGCCGACAGCUCGUcc	ACGAGCUGUCGGCAUUAUG	-2.2	-2.1	-1.5	-1	0	4	-39	53.5	-5.9	4	II	52.6	47.7	54.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0628	NM_015213	Huesken	RAB6IP1	23258	CGGUCUCCGUGUCCAGUCCgc	GGACUGGACACGGAGACCG	-3.3	-2.4	-1.9	0	-1	3	-44.8	52.6	10.8	0	II	68.4	40.2	60.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0629	NM_003347	Huesken	UBE2L3	7332	AGAGUAUUCUUCAGCUAGGuc	CCUAGCUGAAGAAUACUCU	-3.3	-2.1	0.8	2	3	2	-36.3	61.6	-4.9	5	Ia	42.1	59.5	63.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0630	NM_003347	Huesken	UBE2L3	7332	AGUAUUCUUCAGCUAGGUCag	GACCUAGCUGAAGAAUACU	-2.4	-2.1	1.4	1	4	2	-36.4	77.8	14.4	5	Ia	42.1	56.7	101.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0631	NM_003347	Huesken	UBE2L3	7332	AUUCUUCAGCUAGGUCAGCcc	GCUGACCUAGCUGAAGAAU	-3.4	-1.1	-1.5	2	4	2	-38.4	54.9	7.4	4	Ia	47.4	58.1	70.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0632	NM_003347	Huesken	UBE2L3	7332	CUUCAGCUAGGUCAGCCCGaa	CGGGCUGACCUAGCUGAAG	-2.4	-2.1	-3	0	2	5	-43	49	6.1	1	II	63.2	50.7	61.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0633	NM_003347	Huesken	UBE2L3	7332	UCAGCUAGGUCAGCCCGAAgc	UUCGGGCUGACCUAGCUGA	-0.9	-2.4	-3	1	0	5	-43.3	39.4	-6.1	3	II	57.9	44.8	49	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0634	NM_003347	Huesken	UBE2L3	7332	UAGGUCAGCCCGAAGCGGGug	CCCGCUUCGGGCUGACCUA	-3.3	-1.3	-3.7	1	4	5	-45.7	45.6	-4.9	4	Ib	68.4	66.6	62.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0635	NM_003347	Huesken	UBE2L3	7332	GGUCAGCCCGAAGCGGGUGcu	CACCCGCUUCGGGCUGACC	-2.1	-3.3	-4.2	2	1	5	-46.6	25.4	5	0	II	73.7	31.9	60	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0636	NM_003347	Huesken	UBE2L3	7332	UCAGCCCGAAGCGGGUGCUca	AGCACCCGCUUCGGGCUGA	-2.1	-2.4	-4.2	-1	2	5	-46.6	37.9	-6.3	3	II	68.4	46.3	37.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0637	NM_003347	Huesken	UBE2L3	7332	GCCCGAAGCGGGUGCUCAGgc	CUGAGCACCCGCUUCGGGC	-2.1	-3.4	-4.2	1	0	5	-46.6	24.1	0	-1	II	73.7	25.7	51.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0638	NM_003347	Huesken	UBE2L3	7332	CGAAGCGGGUGCUCAGGCUgg	AGCCUGAGCACCCGCUUCG	-2.1	-2.4	-2.5	0	-1	5	-45.4	34.1	-8.3	1	III	68.4	34.5	46.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0639	NM_003347	Huesken	UBE2L3	7332	GAAGCGGGUGCUCAGGCUGgg	CAGCCUGAGCACCCGCUUC	-2.1	-2.4	-2.5	0	2	5	-45.1	36.2	3.1	1	II	68.4	45.1	37.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0640	NM_003347	Huesken	UBE2L3	7332	GUCAUUCACCAGUGCUAUGag	CAUAGCACUGGUGAAUGAC	-2.1	-2.2	0.7	0	0	2	-37.2	65.6	2.3	3	II	47.4	44.1	80.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0641	NM_003347	Huesken	UBE2L3	7332	UCAUUCACCAGUGCUAUGAgg	UCAUAGCACUGGUGAAUGA	-2.4	-2.4	-0.9	1	0	2	-37.4	79	-0.7	9	II	42.1	60.4	77.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0642	NM_003347	Huesken	UBE2L3	7332	CAUUCACCAGUGCUAUGAGgg	CUCAUAGCACUGGUGAAUG	-2.1	-2.1	-1	-1	2	2	-37.1	63.4	2.7	2	II	47.4	40.9	77.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0643	NM_003347	Huesken	UBE2L3	7332	GAGGGACUGGAUUACUUGGuc	CCAAGUAAUCCAGUCCCUC	-3.3	-2.4	3.6	1	1	3	-39.5	56.4	5.3	2	II	52.6	45.3	61.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0644	NM_003347	Huesken	UBE2L3	7332	AGGGACUGGAUUACUUGGUcg	ACCAAGUAAUCCAGUCCCU	-2.2	-2.1	3.3	3	1	3	-39.3	58.7	-0.8	5	II	47.4	51.7	87.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0645	NM_003347	Huesken	UBE2L3	7332	CUGGAUUACUUGGUCGGUUuu	AACCGACCAAGUAAUCCAG	-0.9	-2.1	2	1	-1	3	-37.2	54.8	-0.9	3	II	47.4	46.5	66.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0646	NM_003347	Huesken	UBE2L3	7332	GAUUACUUGGUCGGUUUUGgu	CAAAACCGACCAAGUAAUC	-2.1	-2.4	2.2	1	1	3	-33.6	67.1	0.4	6	II	42.1	47.4	56.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0647	NM_003347	Huesken	UBE2L3	7332	AUUACUUGGUCGGUUUUGGuu	CCAAAACCGACCAAGUAAU	-3.3	-1.1	2.2	3	5	3	-34.5	81.4	0	7	Ia	42.1	64.6	84.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0648	NM_003347	Huesken	UBE2L3	7332	ACUUGGUCGGUUUUGGUUGcu	CAACCAAAACCGACCAAGU	-2.1	-2.2	2.9	3	3	3	-36.4	73.6	5.4	6	Ib	47.4	59.1	87	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0649	NM_003347	Huesken	UBE2L3	7332	UGGUCGGUUUUGGUUGCUGgc	CAGCAACCAAAACCGACCA	-2.1	-2.1		0	3	3	-38.8	61.4	2.3	5	II	52.6	59	60	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0650	NM_003347	Huesken	UBE2L3	7332	CGGUUUUGGUUGCUGGCUUcc	AAGCCAGCAACCAAAACCG	-0.9	-2.4		1	-2	3	-38.5	58.4	-1.2	3	II	52.6	38.9	41.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0651	NM_003347	Huesken	UBE2L3	7332	GUUUUGGUUGCUGGCUUCCag	GGAAGCCAGCAACCAAAAC	-3.3	-2.2	0.4	-1	2	3	-38.5	62.8	8.1	6	II	52.6	52.9	73	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0652	NM_003347	Huesken	UBE2L3	7332	UGGUUGCUGGCUUCCAGUUuu	AACUGGAAGCCAGCAACCA	-0.9	-2.1	-2.7	1	0	3	-40.9	65	-3.3	4	II	52.6	52.7	71.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0653	NM_003347	Huesken	UBE2L3	7332	UUUCGGCACUAAUUACUGGca	CCAGUAAUUAGUGCCGAAA	-3.3	-0.9	0.8	2	5	4	-34.9	73.7	4.6	6	II	42.1	68.3	82.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0654	NM_003347	Huesken	UBE2L3	7332	CACUAAUUACUGGCAGACAga	UGUCUGCCAGUAAUUAGUG	-2.1	-2.1	1.6	0	-3	3	-35.9	57.7	-3.1	4	II	42.1	40.7	51.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0655	NM_003347	Huesken	UBE2L3	7332	ACUAAUUACUGGCAGACAGac	CUGUCUGCCAGUAAUUAGU	-2.1	-2.2	-0.2	3	3	3	-35.9	70.5	5.1	6	Ia	42.1	56.8	52.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0656	NM_003347	Huesken	UBE2L3	7332	UAAUUACUGGCAGACAGACcu	GUCUGUCUGCCAGUAAUUA	-2.2	-1.3	-0.3	1	4	3	-36.2	65.6	5.1	7	Ia	42.1	65.8	91	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0657	NM_003347	Huesken	UBE2L3	7332	AAUUACUGGCAGACAGACCug	GGUCUGUCUGCCAGUAAUU	-3.3	-0.9	-2.1	3	4	3	-38.2	70	9.8	6	Ia	47.4	66.4	74.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0658	NM_003347	Huesken	UBE2L3	7332	UACUGGCAGACAGACCUGCcc	GCAGGUCUGUCUGCCAGUA	-3.4	-1.3	-4.7	1	3	3	-42.9	52	5.1	5	II	57.9	66	52.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0659	NM_003347	Huesken	UBE2L3	7332	CCUGCCCCUUUUCGUCGAUgu	AUCGACGAAAAGGGGCAGG	-1.1	-3.3	1.3	-2	-2	5	-40.9	41.9	-0.6	0	III	57.9	22	32	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0660	NM_003347	Huesken	UBE2L3	7332	UGCCCCUUUUCGUCGAUGUuu	ACAUCGACGAAAAGGGGCA	-2.2	-2.1	1.3	2	0	5	-39.8	70.8	-6.3	5	II	52.6	53.7	64.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0661	NM_003347	Huesken	UBE2L3	7332	CCUUUUCGUCGAUGUUUGGgu	CCAAACAUCGACGAAAAGG	-3.3	-3.3	2	-2	0	2	-34.9	65.3	-2	4	II	47.4	40.7	59.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0662	NM_003347	Huesken	UBE2L3	7332	CGUCGAUGUUUGGGUGAUAga	UAUCACCCAAACAUCGACG	-1.3	-2.4	2.4	0	-4	3	-36.8	37.7	-5.8	2	III	47.4	25.2	57	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0663	NM_003347	Huesken	UBE2L3	7332	AUGUUUGGGUGAUAGAUCUuu	AGAUCUAUCACCCAAACAU	-2.1	-1.1	1	2	1	3	-35.1	77.5	-4	7	II	36.8	61.9	73.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0664	NM_003347	Huesken	UBE2L3	7332	UUUGGGUGAUAGAUCUUUGuu	CAAAGAUCUAUCACCCAAA	-2.1	-0.9	1	1	4	3	-33.6	81.2	2	7	Ib	36.8	72.9	82.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0665	NM_003347	Huesken	UBE2L3	7332	GGGUGAUAGAUCUUUGUUUua	AAACAAAGAUCUAUCACCC	-0.9	-3.3	1	2	-2	3	-33.7	70.4	-4	4	III	36.8	40.5	50.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0666	NM_003347	Huesken	UBE2L3	7332	AUAGAUCUUUGUUUUAAAUgu	AUUUAAAACAAAGAUCUAU	-1.1	-1.1	2.8	1	2	1	-25.5	97.7	4.1	5	II	15.8	57.9	65.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0667	NM_003347	Huesken	UBE2L3	7332	UUUUAAAUGUGAUCUUCGGug	CCGAAGAUCACAUUUAAAA	-3.3	-0.9	1.5	1	5	3	-30.3	89.1	2.7	8	Ia	31.6	72.4	83.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0668	NM_003347	Huesken	UBE2L3	7332	UGAUCUUCGGUGGUUUGAAug	UUCAAACCACCGAAGAUCA	-0.9	-2.1	0.5	2	1	3	-36.1	71.6	-1.4	6	II	42.1	51.9	65.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0669	NM_003347	Huesken	UBE2L3	7332	UCGGUGGUUUGAAUGGGUAcu	UACCCAUUCAAACCACCGA	-1.3	-2.4	2	0	0	3	-38.4	54.4	-4	5	II	47.4	49.5	71.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0670	NM_003347	Huesken	UBE2L3	7332	UUGAAUGGGUACUCUGCUGga	CAGCAGAGUACCCAUUCAA	-2.1	-0.9	-1	1	3	3	-38.1	71.5	2.7	6	Ia	47.4	69	90	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0671	NM_003347	Huesken	UBE2L3	7332	UCUGAAGGCUCCCUUAUCAua	UGAUAAGGGAGCCUUCAGA	-2.1	-2.4	-1	1	1	3	-39.7	60.5	-1	6	II	47.4	53.3	109.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0672	NM_003347	Huesken	UBE2L3	7332	CUCCCUUAUCAUAUGGAGGgu	CCUCCAUAUGAUAAGGGAG	-3.3	-2.1	-3	1	1	3	-37.7	73.1	3.1	1	II	47.4	55.3	81.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0673	NM_003347	Huesken	UBE2L3	7332	AUAUGGAGGGUUGUCAGGAac	UCCUGACAACCCUCCAUAU	-2.4	-1.1	2	2	3	3	-39.7	55.1	1.6	6	II	47.4	56.2	69.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0674	NM_003347	Huesken	UBE2L3	7332	GGAACAAUAAGCCCUUGCCaa	GGCAAGGGCUUAUUGUUCC	-3.3	-3.3	-1.9	0	2	4	-39	63.7	7.5	3	II	52.6	49.8	79.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0675	NM_003347	Huesken	UBE2L3	7332	UAAGCCCUUGCCAAGUCAAua	UUGACUUGGCAAGGGCUUA	-0.9	-1.3	-1.1	0	1	4	-38.8	59.2	-11	4	II	47.4	53.4	61.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0676	NM_003347	Huesken	UBE2L3	7332	AAGCCCUUGCCAAGUCAAUaa	AUUGACUUGGCAAGGGCUU	-1.1	-0.9	-1.1	3	0	4	-38.6	54.4	-8.9	3	II	47.4	44.7	58.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0677	NM_003347	Huesken	UBE2L3	7332	AGCCCUUGCCAAGUCAAUAaa	UAUUGACUUGGCAAGGGCU	-1.3	-2.1	-1	4	-1	4	-39	59.9	0.9	2	II	47.4	44.7	75.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0678	NM_003347	Huesken	UBE2L3	7332	GCCAAGUCAAUAAAUUAGCuu	GCUAAUUUAUUGACUUGGC	-3.4	-3.4	-1.3	1	0	3	-32.4	64	7.5	3	II	36.8	52.6	46.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0679	NM_003347	Huesken	UBE2L3	7332	AAUUAGCUUCAUCAACCUGga	CAGGUUGAUGAAGCUAAUU	-2.1	-0.9	-1.5	1	4	2	-33.4	75.8	10.4	5	Ia	36.8	61	96.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0680	NM_003347	Huesken	UBE2L3	7332	UUAGCUUCAUCAACCUGGAug	UCCAGGUUGAUGAAGCUAA	-2.4	-0.9	-1.5	1	2	2	-37.1	69.3	-8.7	5	II	42.1	63.7	111.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0681	NM_003347	Huesken	UBE2L3	7332	AUCAACCUGGAUGUUACGGaa	CCGUAACAUCCAGGUUGAU	-3.3	-1.1	-0.6	2	5	3	-37.4	70.9	10.4	5	Ib	47.4	60.2	61.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0682	NM_003344	Huesken	UBE2H	7328	UGAGCUGUCCCCGGUACCCuc	GGGUACCGGGGACAGCUCA	-3.3	-2.1	-1.8	0	4	6	-46.7	46	2.7	3	II	68.4	63.8	71.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0683	NM_003344	Huesken	UBE2H	7328	GAGCUGUCCCCGGUACCCUcu	AGGGUACCGGGGACAGCUC	-2.1	-2.4	-0.3	3	1	6	-46.7	38.4	-4	2	III	68.4	42	77.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0684	NM_003344	Huesken	UBE2H	7328	GCUGUCCCCGGUACCCUCUuc	AGAGGGUACCGGGGACAGC	-2.1	-3.4	0.5	1	-1	6	-46.7	44.5	-3.5	2	III	68.4	35.8	65	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0685	NM_003344	Huesken	UBE2H	7328	CCCCGGUACCCUCUUCCUGuu	CAGGAAGAGGGUACCGGGG	-2.1	-3.3	0.1	2	0	6	-45.3	41.1	3.4	0	II	68.4	39.3	74.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0686	NM_003344	Huesken	UBE2H	7328	UUCCUGUUCUUUCAGCGCCuc	GGCGCUGAAAGAACAGGAA	-3.3	-0.9	-1.4	3	4	5	-39.3	72.7	12.8	5	Ib	52.6	75.3	98.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0687	NM_003344	Huesken	UBE2H	7328	UUCUUUCAGCGCCUCCUCCgu	GGAGGAGGCGCUGAAAGAA	-3.3	-0.9	1.3	1	4	5	-41.9	75	9.8	6	Ia	57.9	70.9	91.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0688	NM_003344	Huesken	UBE2H	7328	CAGCGCCUCCUCCGUGGCGua	CGCCACGGAGGAGGCGCUG	-2.4	-2.1	-5.4	0	1	5	-48.1	27.2	-2	-1	II	78.9	38.9	66.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0689	NM_003344	Huesken	UBE2H	7328	AGCGCCUCCUCCGUGGCGUau	ACGCCACGGAGGAGGCGCU	-2.2	-2.1	-5.9	3	2	5	-48.2	40.6	-6.3	1	II	73.7	41.3	71.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0690	NM_003344	Huesken	UBE2H	7328	CGUAUUUCUGGAUGUACUCuu	GAGUACAUCCAGAAAUACG	-2.4	-2.4	1	-1	0	2	-34.5	73.3	5.4	4	II	42.1	52.8	77.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0691	NM_003344	Huesken	UBE2H	7328	GGAUGUACUCUUUAAUUUUcu	AAAAUUAAAGAGUACAUCC	-0.9	-3.3	1.1	0	-2	2	-29	78.4	-1	4	II	26.3	45.2	70.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0692	NM_003344	Huesken	UBE2H	7328	UGUACUCUUUAAUUUUCUGcu	CAGAAAAUUAAAGAGUACA	-2.1	-2.1	2.5	0	4	1	-28.8	99.9	4.6	5	Ib	26.3	66.6	78.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0693	NM_003344	Huesken	UBE2H	7328	UAAUUUUCUGCUUGUAUUCuu	GAAUACAAGCAGAAAAUUA	-2.4	-1.3	3.1	0	3	2	-29	103.8	8.1	9	Ia	26.3	79.7	93.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0694	NM_003344	Huesken	UBE2H	7328	UUUUCUGCUUGUAUUCUUCug	GAAGAAUACAAGCAGAAAA	-2.4	-0.9		0	4	2	-31.1	101.6	10.2	8	Ia	31.6	76	95.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0695	NM_003344	Huesken	UBE2H	7328	UUCUGCUUGUAUUCUUCUGgu	CAGAAGAAUACAAGCAGAA	-2.1	-0.9		2	3	2	-33.5	94.4	5.3	6	Ib	36.8	68.9	77.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0696	NM_003344	Huesken	UBE2H	7328	UCUGCUUGUAUUCUUCUGGuc	CCAGAAGAAUACAAGCAGA	-3.3	-2.4		1	4	2	-35.9	87.7	7.8	7	Ib	42.1	73.1	103.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0697	NM_003344	Huesken	UBE2H	7328	CUUGUAUUCUUCUGGUCGGug	CCGACCAGAAGAAUACAAG	-3.3	-2.1		0	2	3	-36.2	65.9	-4.4	4	II	47.4	53.6	86.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0698	NM_003344	Huesken	UBE2H	7328	GUAUUCUUCUGGUCGGUGGag	CCACCGACCAGAAGAAUAC	-3.3	-2.2		2	2	3	-38.7	76	0	6	II	52.6	53.4	82.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0699	NM_003344	Huesken	UBE2H	7328	UCUGGUCGGUGGAGGUACAug	UGUACCUCCACCGACCAGA	-2.1	-2.4	2.1	0	0	3	-43.4	41.6	-6.3	3	II	57.9	42.8	95.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0700	NM_003344	Huesken	UBE2H	7328	CGGUGGAGGUACAUGGCUGca	CAGCCAUGUACCUCCACCG	-2.1	-2.4	1.8	0	0	3	-43	40.8	-2.3	1	II	63.2	41.7	61.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0701	NM_003344	Huesken	UBE2H	7328	GGUACAUGGCUGCAGCGUCac	GACGCUGCAGCCAUGUACC	-2.4	-3.3	-1.2	2	1	3	-43.2	43.8	9.8	1	II	63.2	40.2	55.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0702	NM_003344	Huesken	UBE2H	7328	ACAUGGCUGCAGCGUCACCau	GGUGACGCUGCAGCCAUGU	-3.3	-2.2	-1.9	1	3	3	-44	43.3	12.1	2	II	63.2	49.4	91	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0703	NM_003344	Huesken	UBE2H	7328	AUGGCUGCAGCGUCACCAUug	AUGGUGACGCUGCAGCCAU	-1.1	-1.1	-2.9	1	1	3	-42.9	50.8	-6.3	2	II	57.9	48.2	86.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0704	NM_003344	Huesken	UBE2H	7328	UGAGAGGAUCUAUGGGGUUag	AACCCCAUAGAUCCUCUCA	-0.9	-2.1	1	-1	1	4	-39.9	45.5	-1.3	6	II	47.4	52.5	49.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0705	NM_003344	Huesken	UBE2H	7328	GAGGAUCUAUGGGGUUAGGau	CCUAACCCCAUAGAUCCUC	-3.3	-2.4	0.3	-1	1	4	-40	47.5	2.7	2	II	52.6	36.8	66.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0706	NM_003344	Huesken	UBE2H	7328	GAUCUAUGGGGUUAGGAUAgg	UAUCCUAACCCCAUAGAUC	-1.3	-2.4	0.3	3	-2	4	-37	64.3	-0.7	4	II	42.1	38	50.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0707	NM_003344	Huesken	UBE2H	7328	GGGGUUAGGAUAGGCCAAUaa	AUUGGCCUAUCCUAACCCC	-1.1	-3.3	0.4	0	-3	4	-40.7	36.2	-4	3	III	52.6	32.5	36.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0708	NM_003344	Huesken	UBE2H	7328	AGGAUAGGCCAAUAACUGAgg	UCAGUUAUUGGCCUAUCCU	-2.4	-2.1	0.6	2	-1	4	-37.4	58.4	-1.5	6	II	42.1	46.7	66.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0709	NM_003344	Huesken	UBE2H	7328	AGGCAGGAAGGACUCAAAUau	AUUUGAGUCCUUCCUGCCU	-1.1	-2.1	1.7	2	0	3	-39.1	49.1	3.5	4	II	47.4	43.2	48.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0710	NM_003344	Huesken	UBE2H	7328	GGAAGGACUCAAAUAUAUUgg	AAUAUAUUUGAGUCCUUCC	-0.9	-3.3	2.4	0	-1	2	-31.8	62.2	-1.9	3	III	31.6	42.8	41.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0711	NM_003344	Huesken	UBE2H	7328	GAAGGACUCAAAUAUAUUGgu	CAAUAUAUUUGAGUCCUUC	-2.1	-2.4	0.4	1	1	2	-30.6	73.2	2.3	4	II	31.6	54.1	84.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0712	NM_003344	Huesken	UBE2H	7328	GGACUCAAAUAUAUUGGUAag	UACCAAUAUAUUUGAGUCC	-1.3	-3.3	0.1	1	-1	2	-32	68.8	1.3	3	III	31.6	34.9	48.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0713	NM_003344	Huesken	UBE2H	7328	CAAAUAUAUUGGUAAGAUCau	GAUCUUACCAAUAUAUUUG	-2.4	-2.1	1.2	0	0	2	-28.5	81.3	5.4	5	II	26.3	58.7	78.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0714	NM_003344	Huesken	UBE2H	7328	AAAUAUAUUGGUAAGAUCAua	UGAUCUUACCAAUAUAUUU	-2.1	-0.9	2	1	1	2	-28.5	91.5	-0.6	8	II	21.1	68.6	68.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0715	NM_003344	Huesken	UBE2H	7328	UAUAUUGGUAAGAUCAUAGag	CUAUGAUCUUACCAAUAUA	-2.1	-1.3	1.7	0	4	2	-30.1	100	2	10	Ia	26.3	80	110	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0716	NM_003344	Huesken	UBE2H	7328	UAAGAUCAUAGAGAGCUGUcc	ACAGCUCUCUAUGAUCUUA	-2.2	-1.3	0.8	0	2	2	-35.6	68	-1.3	8	II	36.8	67.3	95.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0717	NM_003344	Huesken	UBE2H	7328	UCAUAGAGAGCUGUCCAAGuu	CUUGGACAGCUCUCUAUGA	-2.1	-2.4	-0.6	0	3	2	-38.6	62.3	5.7	7	Ia	47.4	61.7	81	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0718	NM_003344	Huesken	UBE2H	7328	CAUAGAGAGCUGUCCAAGUuu	ACUUGGACAGCUCUCUAUG	-2.2	-2.1	-0.6	0	-1	2	-38.4	54.2	-6	4	II	47.4	45.9	86	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0719	NM_003344	Huesken	UBE2H	7328	GUUUGAUUAAUUACAUCUAga	UAGAUGUAAUUAAUCAAAC	-1.3	-2.2	-0.9	1	-1	1	-27.2	83.7	-3.3	5	II	21.1	47.5	46.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0720	NM_003344	Huesken	UBE2H	7328	UGAUUAAUUACAUCUAGACac	GUCUAGAUGUAAUUAAUCA	-2.2	-2.1	-0.9	0	3	1	-29.9	91.9	5.1	8	Ia	26.3	71.3	105.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0721	NM_003344	Huesken	UBE2H	7328	ACAUCUAGACACACAGUUCcu	GAACUGUGUGUCUAGAUGU	-2.4	-2.2	0.4	1	2	1	-36.2	70.7	4.8	6	Ia	42.1	60.3	98.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0722	NM_003344	Huesken	UBE2H	7328	AUCUAGACACACAGUUCCUga	AGGAACUGUGUGUCUAGAU	-2.1	-1.1	0.3	0	2	2	-37.3	63.7	-3.9	6	II	42.1	55.7	100.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0723	NM_003344	Huesken	UBE2H	7328	AGACACACAGUUCCUGACGcu	CGUCAGGAACUGUGUGUCU	-2.4	-2.1	0.8	2	3	2	-39.5	58.7	8.1	5	Ib	52.6	60.2	99.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0724	NM_003344	Huesken	UBE2H	7328	AUGGAAAAUUUUAUUCAUGaa	CAUGAAUAAAAUUUUCCAU	-2.1	-1.1	0.7	1	3	2	-26.4	80.9	5.5	5	Ia	21.1	67.6	64	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0725	NM_003344	Huesken	UBE2H	7328	UUUUAUUCAUGAAUCCUAUag	AUAGGAUUCAUGAAUAAAA	-1.1	-0.9	1.8	1	2	2	-28.3	99.7	-1.5	9	II	21.1	69	106.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0726	NM_003344	Huesken	UBE2H	7328	UUUAUUCAUGAAUCCUAUAga	UAUAGGAUUCAUGAAUAAA	-1.3	-0.9	1.8	0	0	2	-28.7	95.4	-1.5	7	II	21.1	66.1	67.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0727	NM_003344	Huesken	UBE2H	7328	AUUCAUGAAUCCUAUAGAUgg	AUCUAUAGGAUUCAUGAAU	-1.1	-1.1	0.7	2	2	2	-31.2	76.7	-6	6	II	26.3	54.1	95.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0728	NM_003344	Huesken	UBE2H	7328	AUCCUAUAGAUGGAGAUUUga	AAAUCUCCAUCUAUAGGAU	-0.9	-1.1	-1.5	4	0	2	-33.4	70.7	-4	6	II	31.6	59.2	96.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0729	NM_003344	Huesken	UBE2H	7328	UGGAGAUUUGAAAGGGUAUuu	AUACCCUUUCAAAUCUCCA	-1.1	-2.1	5.1	0	-1	3	-34.8	65.8	-4.3	6	II	36.8	52.8	99.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0730	NM_003344	Huesken	UBE2H	7328	AUUUGAAAGGGUAUUUAUCag	GAUAAAUACCCUUUCAAAU	-2.4	-1.1	1.4	2	4	3	-29.1	88.6	10.2	6	Ia	26.3	67.1	101.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0731	NM_003344	Huesken	UBE2H	7328	AUUUAUCAGGUAGGUCCACuc	GUGGACCUACCUGAUAAAU	-2.2	-1.1	0	1	4	2	-36.3	58.6	10.1	6	Ia	42.1	55.6	77.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0732	NM_003344	Huesken	UBE2H	7328	UUUAUCAGGUAGGUCCACUcu	AGUGGACCUACCUGAUAAA	-2.1	-0.9	0	1	3	2	-37.3	77.5	0.7	8	II	42.1	69.1	108.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0733	NM_003344	Huesken	UBE2H	7328	GGUAGGUCCACUCUAACUUuc	AAGUUAGAGUGGACCUACC	-0.9	-3.3	0.3	2	0	2	-38.4	64.5	1.4	4	III	47.4	43.1	64.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0734	NM_003344	Huesken	UBE2H	7328	GUAGGUCCACUCUAACUUUcc	AAAGUUAGAGUGGACCUAC	-0.9	-2.2	0.3	0	-1	2	-36	56.5	-6.3	3	III	42.1	43.6	50	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0735	NM_003344	Huesken	UBE2H	7328	ACUCUAACUUUCCAUACUCcg	GAGUAUGGAAAGUUAGAGU	-2.4	-2.2	2.7	2	3	2	-34	67.7	7.5	5	Ia	36.8	60.2	83.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0736	NM_003344	Huesken	UBE2H	7328	AUACUCCGCCUUCAUAUGGug	CCAUAUGAAGGCGGAGUAU	-3.3	-1.1	0.6	3	4	5	-37.9	68.2	5.4	6	Ib	47.4	63.5	101.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0737	NM_003344	Huesken	UBE2H	7328	UCCGCCUUCAUAUGGUGUUcc	AACACCAUAUGAAGGCGGA	-0.9	-2.4	0.1	1	0	5	-38.6	66.2	-4	5	II	47.4	53.6	67.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0738	NM_003344	Huesken	UBE2H	7328	CUUCAUAUGGUGUUCCUUGug	CAAGGAACACCAUAUGAAG	-2.1	-2.1	-0.7	1	1	2	-34.6	73.9	3	5	II	42.1	60.2	99.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0739	NM_003344	Huesken	UBE2H	7328	GGUGUUCCUUGUGGUCCAUaa	AUGGACCACAAGGAACACC	-1.1	-3.3	-0.8	-1	-1	2	-40.2	47.4	-1	2	III	52.6	23.5	34	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0740	NM_003344	Huesken	UBE2H	7328	UGUUCCUUGUGGUCCAUAAaa	UUAUGGACCACAAGGAACA	-0.9	-2.1	-0.8	2	-1	2	-36.9	83.6	-3.8	7	II	42.1	50	91.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0741	NM_003344	Huesken	UBE2H	7328	GUGGUCCAUAAAACUUCACua	GUGAAGUUUUAUGGACCAC	-2.2	-2.2	0.5	0	1	2	-34.6	64.2	7.1	3	II	42.1	48.4	63.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0742	NM_003344	Huesken	UBE2H	7328	UGGUCCAUAAAACUUCACUac	AGUGAAGUUUUAUGGACCA	-2.1	-2.1	0.5	0	1	2	-34.5	87.2	3.1	6	II	36.8	64.9	95.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0743	NM_003344	Huesken	UBE2H	7328	UCCAUAAAACUUCACUACAaa	UGUAGUGAAGUUUUAUGGA	-2.1	-2.4	1.1	0	-1	2	-32.5	75.4	1.7	6	II	31.6	58.8	75.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0744	NM_003344	Huesken	UBE2H	7328	AAAACUUCACUACAAAUUCau	GAAUUUGUAGUGAAGUUUU	-2.4	-0.9	0	2	3	1	-28.5	87.7	9.8	7	Ia	26.3	74	96.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0745	NM_003344	Huesken	UBE2H	7328	CCUCCCAGGAUCGUAACCUca	AGGUUACGAUCCUGGGAGG	-2.1	-3.3	-1.2	1	0	3	-42.2	45.2	-6	1	III	57.9	43.2	84.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0746	NM_003344	Huesken	UBE2H	7328	CUCCCAGGAUCGUAACCUCau	GAGGUUACGAUCCUGGGAG	-2.4	-2.1	-1.6	0	0	3	-41.3	44	3.1	0	II	57.9	42.8	57.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0747	NM_003344	Huesken	UBE2H	7328	CCCAGGAUCGUAACCUCAUgu	AUGAGGUUACGAUCCUGGG	-1.1	-3.3	-1.6	0	-3	3	-40	42.6	-8.6	1	III	52.6	37.6	77.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0748	NM_003344	Huesken	UBE2H	7328	AACCUCAUGUUUACUCUCGau	CGAGAGUAAACAUGAGGUU	-2.4	-0.9	1.3	3	3	2	-35.1	75.7	0.4	6	Ib	42.1	66.1	98	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0749	NM_003344	Huesken	UBE2H	7328	CCUCAUGUUUACUCUCGAUga	AUCGAGAGUAAACAUGAGG	-1.1	-3.3	2.3	0	-2	2	-35.5	62.4	-3.3	3	III	42.1	34.8	71.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0750	NM_003344	Huesken	UBE2H	7328	CUCAUGUUUACUCUCGAUGag	CAUCGAGAGUAAACAUGAG	-2.1	-2.1	2.2	0	0	2	-34.3	82.1	3.4	5	II	42.1	60.1	70.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0751	NM_003344	Huesken	UBE2H	7328	UCAUGUUUACUCUCGAUGAgc	UCAUCGAGAGUAAACAUGA	-2.4	-2.4	1.4	1	0	2	-34.6	81.4	-6.1	7	II	36.8	62.1	71.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0752	NM_003345	Huesken	UBE2I	7329	UUUGGCAGUAAAUCGUGUAgg	UACACGAUUUACUGCCAAA	-1.3	-0.9	2.4	0	1	3	-33.8	75.7	-1.5	7	II	36.8	62.5	92.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0753	NM_003345	Huesken	UBE2I	7329	GGCAGUAAAUCGUGUAGGCcu	GCCUACACGAUUUACUGCC	-3.4	-3.3	1.9	-1	1	3	-38.7	51.3	5.1	2	II	52.6	38.9	67.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0754	NM_003345	Huesken	UBE2I	7329	UAAAUCGUGUAGGCCUCUGcu	CAGAGGCCUACACGAUUUA	-2.1	-1.3	1.5	1	4	4	-37.6	70.7	2.3	8	Ia	47.4	69.2	83.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0755	NM_003345	Huesken	UBE2I	7329	GUAGGCCUCUGCUUGAGCUgg	AGCUCAAGCAGAGGCCUAC	-2.1	-2.2	-1.9	1	2	4	-42.8	54.8	-4	0	III	57.9	42.1	89.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0756	NM_003345	Huesken	UBE2I	7329	CUGCUUGAGCUGGGUCUUGga	CAAGACCCAGCUCAAGCAG	-2.1	-2.1	-1.4	0	-1	3	-41.1	41.3	-2	2	II	57.9	44.9	75.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0757	NM_003345	Huesken	UBE2I	7329	UGGGUCUUGGAUAUUUGGUuc	ACCAAAUAUCCAAGACCCA	-2.2	-2.1	3	2	2	3	-37	79	1.1	5	II	42.1	60.6	83.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0758	NM_003345	Huesken	UBE2I	7329	GGGUCUUGGAUAUUUGGUUca	AACCAAAUAUCCAAGACCC	-0.9	-3.3	3	2	-1	3	-35.8	70	-1.6	3	III	42.1	40.8	48.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0759	NM_003345	Huesken	UBE2I	7329	UAUUUGGUUCAUUUAGAAGuu	CUUCUAAAUGAACCAAAUA	-2.1	-1.3	0.2	0	4	2	-28.9	101.7	7.7	8	Ia	26.3	71.5	88.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0760	NM_003345	Huesken	UBE2I	7329	CAUUUAGAAGUUCCUGUAUuc	AUACAGGAACUUCUAAAUG	-1.1	-2.1	0.9	-1	-2	2	-31.4	77.5	-0.6	6	II	31.6	42.9	52.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0761	NM_003345	Huesken	UBE2I	7329	AGUUCCUGUAUUCCUAAUAgg	UAUUAGGAAUACAGGAACU	-1.3	-2.1	2.4	2	-1	2	-33	85.7	1.7	6	II	31.6	51.8	71.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0762	NM_003345	Huesken	UBE2I	7329	UGUAUUCCUAAUAGGAUCUgu	AGAUCCUAUUAGGAAUACA	-2.1	-2.1	-2.4	-1	1	2	-33.4	89.6	-1.2	7	II	31.6	66.5	90.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0763	NM_003345	Huesken	UBE2I	7329	GUAUUCCUAAUAGGAUCUGuu	CAGAUCCUAUUAGGAAUAC	-2.1	-2.2	-2.4	-1	2	2	-33.4	63.9	0	4	II	36.8	48.2	74.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0764	NM_003345	Huesken	UBE2I	7329	UAGGAUCUGUUUGAUUGUGau	CACAAUCAAACAGAUCCUA	-2.1	-1.3	0.7	1	3	2	-33.7	71.4	5.7	5	Ib	36.8	64.8	87.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0765	NM_003345	Huesken	UBE2I	7329	CUGUUUGAUUGUGAUGGCUgg	AGCCAUCACAAUCAAACAG	-2.1	-2.1	4.4	-1	-1	3	-35.5	66.6	-3	4	II	42.1	47.9	60.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0766	NM_003345	Huesken	UBE2I	7329	GUUUGAUUGUGAUGGCUGGcc	CCAGCCAUCACAAUCAAAC	-3.3	-2.2	4.4	1	2	3	-36.7	64.4	0	5	II	47.4	46.2	56	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0767	NM_003345	Huesken	UBE2I	7329	UGGCCUCCAGUCCUUGUCCuc	GGACAAGGACUGGAGGCCA	-3.3	-2.1	-0.9	1	3	4	-45	61.5	9.8	3	II	63.2	63	85.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0768	NM_003345	Huesken	UBE2I	7329	UCCAGUCCUUGUCCUCCUCua	GAGGAGGACAAGGACUGGA	-2.4	-2.4	0.5	0	2	2	-43.1	62.5	12.8	3	II	57.9	56	70.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0769	NM_003345	Huesken	UBE2I	7329	UCUAAGAUGGACAGGCACAcu	UGUGCCUGUCCAUCUUAGA	-2.1	-2.4	0.3	0	0	3	-39.6	55.5	-3.7	7	II	47.4	56.8	76	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0770	NM_003345	Huesken	UBE2I	7329	AAGAUGGACAGGCACACUGuc	CAGUGUGCCUGUCCAUCUU	-2.1	-0.9	-0.2	2	3	3	-40.2	60.5	2.4	7	Ib	52.6	66	80.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0771	NM_003345	Huesken	UBE2I	7329	AGAUGGACAGGCACACUGUcc	ACAGUGUGCCUGUCCAUCU	-2.2	-2.1	-1.4	1	1	3	-41.5	50.7	-8.9	5	II	52.6	51.3	59.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0772	NM_003345	Huesken	UBE2I	7329	GGACAGGCACACUGUCCCCga	GGGGACAGUGUGCCUGUCC	-3.3	-3.3	-7.5	0	2	4	-46.1	33.9	10.1	1	II	68.4	41.5	47.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0773	NM_003345	Huesken	UBE2I	7329	GGCACACUGUCCCCGAAGGgu	CCUUCGGGGACAGUGUGCC	-3.3	-3.3	-3.8	1	0	5	-45.1	40.1	-2.3	-1	II	68.4	31.2	51.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0774	NM_003345	Huesken	UBE2I	7329	UCCCCGAAGGGUACACAUUcg	AAUGUGUACCCUUCGGGGA	-0.9	-2.4	-7.4	2	-1	5	-40.8	51.3	-3.5	3	II	52.6	50.6	59.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0775	NM_003345	Huesken	UBE2I	7329	CCCGAAGGGUACACAUUCGgg	CGAAUGUGUACCCUUCGGG	-2.4	-3.3	-2.8	0	-1	4	-39.9	38.5	-1.9	1	II	57.9	40.3	45.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0776	NM_003345	Huesken	UBE2I	7329	GGGUACACAUUCGGGUGAAau	UUCACCCGAAUGUGUACCC	-0.9	-3.3	-0.4	-1	-3	4	-39.7	37.5	-3.4	3	III	52.6	19	49.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0777	NM_003345	Huesken	UBE2I	7329	UACACAUUCGGGUGAAAUAau	UAUUUCACCCGAAUGUGUA	-1.3	-1.3	-0.4	1	-1	4	-34.2	76.5	-3.8	6	II	36.8	55.2	78.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0778	NM_003345	Huesken	UBE2I	7329	AUUCGGGUGAAAUAAUGGUgg	ACCAUUAUUUCACCCGAAU	-2.2	-1.1	0.5	3	3	4	-33.9	66.5	-1.7	6	II	36.8	58.8	88.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0779	NM_003345	Huesken	UBE2I	7329	GAAAUAAUGGUGGUUCGAAuu	UUCGAACCACCAUUAUUUC	-0.9	-2.4	2.7	1	0	2	-32.8	60.2	-1.4	5	II	36.8	38.9	59.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0780	NM_003345	Huesken	UBE2I	7329	AAAUAAUGGUGGUUCGAAUuu	AUUCGAACCACCAUUAUUU	-1.1	-0.9	3.8	3	2	2	-31.5	78.8	1.1	7	II	31.6	52.8	81	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0781	NM_003345	Huesken	UBE2I	7329	AAUGGUGGUUCGAAUUUACau	GUAAAUUCGAACCACCAUU	-2.2	-0.9	2.1	1	3	2	-32.6	69.1	2.5	6	Ib	36.8	60	89.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0782	NM_003345	Huesken	UBE2I	7329	UGGUGGUUCGAAUUUACAUuu	AUGUAAAUUCGAACCACCA	-1.1	-2.1	1.9	2	1	2	-33.8	81.3	0.7	5	II	36.8	59.4	75	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0783	NM_003345	Huesken	UBE2I	7329	GUGGUUCGAAUUUACAUUUug	AAAUGUAAAUUCGAACCAC	-0.9	-2.2	1.9	0	-2	2	-30.2	77.4	-1	4	III	31.6	50.1	53.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0784	NM_003345	Huesken	UBE2I	7329	UUCGAAUUUACAUUUUGGUgg	ACCAAAAUGUAAAUUCGAA	-2.2	-0.9	1.9	1	3	2	-28.9	90.7	-1.3	7	II	26.3	69.1	86.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0785	NM_003345	Huesken	UBE2I	7329	UGGCGAAGAUGGAUAAUCAuc	UGAUUAUCCAUCUUCGCCA	-2.1	-2.1	0.8	1	0	4	-36.8	58.6	-4	5	II	42.1	52.5	59	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0786	NM_003345	Huesken	UBE2I	7329	CGAAGAUGGAUAAUCAUCUuu	AGAUGAUUAUCCAUCUUCG	-2.1	-2.4	-3.4	1	-1	2	-33.6	63.8	-6.2	4	II	36.8	54.6	52.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0787	NM_003345	Huesken	UBE2I	7329	AUGGAUAAUCAUCUUUGAAaa	UUCAAAGAUGAUUAUCCAU	-0.9	-1.1	0.5	1	1	2	-30.6	82.1	9	5	II	26.3	52.2	65.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0788	NM_003345	Huesken	UBE2I	7329	CAUCUUUGAAAAGCAUCCGua	CGGAUGCUUUUCAAAGAUG	-2.4	-2.1	-0.3	1	2	3	-33.5	71.3	0.3	5	II	42.1	61.1	87.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0789	NM_003345	Huesken	UBE2I	7329	AAAAGCAUCCGUAGUUUAAac	UUAAACUACGGAUGCUUUU	-0.9	-0.9	2.9	1	0	3	-31.3	75.6	-3.3	7	II	31.6	49.2	50.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0790	NM_003345	Huesken	UBE2I	7329	AGCAUCCGUAGUUUAAACAag	UGUUUAAACUACGGAUGCU	-2.1	-2.1	1.2	1	0	3	-33.8	80	1.6	5	II	36.8	49.8	68.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0791	NM_003345	Huesken	UBE2I	7329	AUCCGUAGUUUAAACAAGCcu	GCUUGUUUAAACUACGGAU	-3.4	-1.1	0.6	2	3	3	-32.6	64.1	4.8	4	Ib	36.8	69.3	92.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0792	NM_003345	Huesken	UBE2I	7329	CGUAGUUUAAACAAGCCUCcu	GAGGCUUGUUUAAACUACG	-2.4	-2.4	1.2	0	0	3	-33.6	72.3	2.8	4	II	42.1	58.5	73.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0793	NM_003345	Huesken	UBE2I	7329	GUAGUUUAAACAAGCCUCCuu	GGAGGCUUGUUUAAACUAC	-3.3	-2.2	1.5	0	2	3	-34.5	66.3	2.5	6	II	42.1	63.9	82.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0794	NM_003345	Huesken	UBE2I	7329	UAAACAAGCCUCCUUCCCAcg	UGGGAAGGAGGCUUGUUUA	-2.1	-1.3	0.6	1	3	3	-39	67.8	-1.4	7	II	47.4	65.8	78	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0795	NM_003345	Huesken	UBE2I	7329	CAAGCCUCCUUCCCACGGAgu	UCCGUGGGAAGGAGGCUUG	-2.4	-2.1	-2.3	1	-1	3	-44	43.1	-5.7	1	III	63.2	39.7	52.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0796	NM_003345	Huesken	UBE2I	7329	UCCUUCCCACGGAGUCCCUuu	AGGGACUCCGUGGGAAGGA	-2.1	-2.4	-1.6	-1	1	3	-45.5	48.8	-6.6	3	II	63.2	45.8	72.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0797	NM_003345	Huesken	UBE2I	7329	UUCCCACGGAGUCCCUUUCuu	GAAAGGGACUCCGUGGGAA	-2.4	-0.9	-0.8	2	2	3	-41.9	66.5	12.8	5	II	57.9	61.1	89.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0798	NM_003345	Huesken	UBE2I	7329	UCCCACGGAGUCCCUUUCUuu	AGAAAGGGACUCCGUGGGA	-2.1	-2.4	-0.8	1	0	3	-43.1	51.6	-1.2	5	II	57.9	52.3	63.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0799	NM_003345	Huesken	UBE2I	7329	CCCACGGAGUCCCUUUCUUuc	AAGAAAGGGACUCCGUGGG	-0.9	-3.3	-0.8	0	-2	3	-41.6	44.9	-5.9	1	III	57.9	30.5	45.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0800	NM_003345	Huesken	UBE2I	7329	CACGGAGUCCCUUUCUUUCcu	GAAAGAAAGGGACUCCGUG	-2.4	-2.1	-0.8	0	0	3	-38.3	64.5	8.4	3	II	52.6	49.4	53.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0801	NM_003345	Huesken	UBE2I	7329	GAGUCCCUUUCUUUCCUGGaa	CCAGGAAAGAAAGGGACUC	-3.3	-2.4	0.4	0	2	3	-39.1	73.5	3	3	II	52.6	45.8	54.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0802	NM_003345	Huesken	UBE2I	7329	UCCCUUUCUUUCCUGGAAUgg	AUUCCAGGAAAGAAAGGGA	-1.1	-2.4	-0.9	2	0	3	-36.8	73.9	-1.6	5	II	42.1	53.8	83.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0803	NM_003345	Huesken	UBE2I	7329	UUCCUGGAAUGGCGCACUCcc	GAGUGCGCCAUUCCAGGAA	-2.4	-0.9	-1.6	0	3	5	-41.9	52.6	9.8	4	II	57.9	60.9	72.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0804	NM_003345	Huesken	UBE2I	7329	GCACUCCCAGUUCAUGAGGuu	CCUCAUGAACUGGGAGUGC	-3.3	-3.4	-1.8	1	1	3	-41.6	47.2	5.4	0	II	57.9	39.8	72.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0805	NM_003345	Huesken	UBE2I	7329	CACUCCCAGUUCAUGAGGUuc	ACCUCAUGAACUGGGAGUG	-2.2	-2.1	-1.8	0	0	3	-40.4	55	-8.6	1	III	52.6	38.2	58.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0806	NM_003345	Huesken	UBE2I	7329	ACUCCCAGUUCAUGAGGUUca	AACCUCAUGAACUGGGAGU	-0.9	-2.2	-1.8	1	1	3	-39.2	49.5	-6.3	3	II	47.4	38.9	34.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0807	NM_003345	Huesken	UBE2I	7329	CAGUUCAUGAGGUUCAUCGug	CGAUGAACCUCAUGAACUG	-2.4	-2.1	-0.3	0	1	2	-36.3	82.3	0.3	6	II	47.4	62.9	78.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0808	NM_003345	Huesken	UBE2I	7329	UUCAUGAGGUUCAUCGUGCca	GCACGAUGAACCUCAUGAA	-3.4	-0.9	-0.3	1	4	2	-37.6	72.4	4.8	8	Ia	47.4	75.9	84.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0809	NM_003345	Huesken	UBE2I	7329	AGGUUCAUCGUGCCAUCGGga	CCGAUGGCACGAUGAACCU	-3.3	-2.1	0.5	2	3	3	-41.2	59	2.4	4	Ib	57.9	57	81.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0810	NM_003345	Huesken	UBE2I	7329	GGUUCAUCGUGCCAUCGGGau	CCCGAUGGCACGAUGAACC	-3.3	-3.3	0.5	2	2	4	-42.4	50.3	0.1	2	II	63.2	37.7	55	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0811	NM_003345	Huesken	UBE2I	7329	GUUCAUCGUGCCAUCGGGAuu	UCCCGAUGGCACGAUGAAC	-2.4	-2.2	0.5	1	1	4	-41.5	43.5	-6	2	II	57.9	36.6	48.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0812	NM_003345	Huesken	UBE2I	7329	GACAGCCACGAAACCAAAUgg	AUUUGGUUUCGUGGCUGUC	-1.1	-2.4	-0.7	1	-2	3	-36.9	51.8	-4.3	2	III	47.4	35.6	51.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0813	NM_003345	Huesken	UBE2I	7329	GCCACGAAACCAAAUGGGUgg	ACCCAUUUGGUUUCGUGGC	-2.2	-3.4	-2	0	-1	3	-39	40.5	-8.9	1	III	52.6	33.1	56.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0814	NM_003345	Huesken	UBE2I	7329	CCACGAAACCAAAUGGGUGgu	CACCCAUUUGGUUUCGUGG	-2.1	-3.3	-1.6	1	1	3	-37.7	42.8	0	1	II	52.6	44.4	85.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0815	NM_003345	Huesken	UBE2I	7329	GAAACCAAAUGGGUGGUCUuu	AGACCACCCAUUUGGUUUC	-2.1	-2.4	-3.9	0	1	3	-37.7	63.9	-1.6	4	II	47.4	44.8	79.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0816	NM_014501	Huesken	UBE2S	27338	UUCUUAUCGCGCUCGCCAGca	CUGGCGAGCGCGAUAAGAA	-2.1	-0.9	-1.5	2	3	5	-40.5	69.8	-2.4	5	Ia	57.9	62.8	82.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0817	NM_014501	Huesken	UBE2S	27338	UUAUCGCGCUCGCCAGCAUgc	AUGCUGGCGAGCGCGAUAA	-1.1	-0.9	-2.3	1	2	5	-41.7	53.6	-3.9	4	II	57.9	50.4	71.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0818	NM_014501	Huesken	UBE2S	27338	GCCAGCAUGCUUCUUGGCCau	GGCCAAGAAGCAUGCUGGC	-3.3	-3.4	-2.8	1	2	4	-43.5	51.9	15.2	0	II	63.2	43.5	57.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0819	NM_014501	Huesken	UBE2S	27338	GCCAUGGGACCCUCAGCCCcu	GGGCUGAGGGUCCCAUGGC	-3.3	-3.4	-4.3	0	1	4	-48.5	34.8	2.7	1	II	73.7	40.3	45.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0820	NM_014501	Huesken	UBE2S	27338	CCAUGGGACCCUCAGCCCCuc	GGGGCUGAGGGUCCCAUGG	-3.3	-3.3	-8.5	0	1	5	-48.4	33.6	8.5	1	II	73.7	47.4	42.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0821	NM_014501	Huesken	UBE2S	27338	AUGGGACCCUCAGCCCCUCcc	GAGGGGCUGAGGGUCCCAU	-2.4	-1.1	-8.7	2	3	5	-47.5	32	5.1	1	II	68.4	51.7	45	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0822	NM_014501	Huesken	UBE2S	27338	GGCCCCAGGGUCGGUGGAGga	CUCCACCGACCCUGGGGCC	-2.1	-3.3	-3.7	1	0	6	-49.8	16.6	-2.4	-1	II	78.9	23	44	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0823	NM_014501	Huesken	UBE2S	27338	AGGGUCGGUGGAGGAAGCUuc	AGCUUCCUCCACCGACCCU	-2.1	-2.1	2.2	0	1	3	-45.3	29.9	-4	3	II	63.2	41.9	49.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0824	NM_014501	Huesken	UBE2S	27338	GUGGAGGAAGCUUCAGUGCca	GCACUGAAGCUUCCUCCAC	-3.4	-2.2	-0.7	0	1	2	-41.5	48.9	10.8	3	II	57.9	48.7	58.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0825	NM_014501	Huesken	UBE2S	27338	AAGCUUCAGUGCCACUGGCca	GCCAGUGGCACUGAAGCUU	-3.4	-0.9	-2.7	3	4	3	-42.2	54.5	7.5	2	Ib	57.9	56.2	57.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0826	NM_014501	Huesken	UBE2S	27338	GUGCCACUGGCCAGGGCCCga	GGGCCCUGGCCAGUGGCAC	-3.3	-2.2	-5.7	1	2	6	-50.3	24.1	0.1	-1	II	78.9	39.1	43	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0827	NM_014501	Huesken	UBE2S	27338	ACUGGCCAGGGCCCGACCGgc	CGGUCGGGCCCUGGCCAGU	-2.4	-2.2	-7.1	2	4	7	-49.9	31.2	0.1	1	II	78.9	48.4	41.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0828	NM_014501	Huesken	UBE2S	27338	GGCCAGGGCCCGACCGGCUuc	AGCCGGUCGGGCCCUGGCC	-2.1	-3.3	-6.3	2	-1	7	-52.3	12	-6.2	0	III	84.2	27.5	43	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0829	NM_014501	Huesken	UBE2S	27338	GCCCGACCGGCUUCGGCCCug	GGGCCGAAGCCGGUCGGGC	-3.3	-3.4	-7.3	2	1	6	-50.5	23.4	8.1	-2	II	84.2	31.7	36.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0830	NM_014501	Huesken	UBE2S	27338	CCCGACCGGCUUCGGCCCUgc	AGGGCCGAAGCCGGUCGGG	-2.1	-3.3	-7.3	-1	-2	6	-49.2	17.5	2.2	-1	III	78.9	24.8	49.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0831	NM_014501	Huesken	UBE2S	27338	UUCGGCCCUGCCGCUGGGCcc	GCCCAGCGGCAGGGCCGAA	-3.4	-0.9	-6.4	0	4	6	-49.9	35.5	2.7	2	II	78.9	57	42	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0832	NM_014501	Huesken	UBE2S	27338	CGUGGAUCUCUGUGAGCAGac	CUGCUCACAGAGAUCCACG	-2.1	-2.4	-0.8	-1	0	2	-41	39.9	-2	1	II	57.9	36.2	54.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0833	NM_014501	Huesken	UBE2S	27338	AUCUCUGUGAGCAGACGGGcc	CCCGUCUGCUCACAGAGAU	-3.3	-1.1	-2.6	1	4	4	-42.2	56.5	-4.9	4	Ib	57.9	57.9	70.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0834	NM_014501	Huesken	UBE2S	27338	GUGAGCAGACGGGCCCGAGcu	CUCGGGCCCGUCUGCUCAC	-2.1	-2.2	-4.4	0	1	8	-46.9	31.2	0	1	II	73.7	36.9	55	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0835	NM_014501	Huesken	UBE2S	27338	ACGGGCCCGAGCUGCAUACuc	GUAUGCAGCUCGGGCCCGU	-2.2	-2.2	-0.6	1	1	8	-45.8	40.1	5.1	3	II	68.4	43.7	47	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0836	NM_014501	Huesken	UBE2S	27338	CGGGCCCGAGCUGCAUACUcc	AGUAUGCAGCUCGGGCCCG	-2.1	-2.4	-0.6	-1	-3	8	-45.7	32.8	-5.3	-1	III	68.4	28.8	49.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0837	NM_014501	Huesken	UBE2S	27338	GGGCCCGAGCUGCAUACUCcu	GAGUAUGCAGCUCGGGCCC	-2.4	-3.3	-3.6	2	0	7	-45.7	32.9	9.8	-1	II	68.4	36.8	53.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0838	NM_014501	Huesken	UBE2S	27338	CCCGAGCUGCAUACUCCUCgu	GAGGAGUAUGCAGCUCGGG	-2.4	-3.3	-3.6	0	-1	4	-43.5	40	10.8	-1	II	63.2	38.3	56.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0839	NM_014501	Huesken	UBE2S	27338	CUGCAUACUCCUCGUAGUUcu	AACUACGAGGAGUAUGCAG	-0.9	-2.1	-0.3	-1	-2	2	-37.7	54.5	-0.2	3	II	47.4	41.4	40	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0840	NM_014501	Huesken	UBE2S	27338	AUACUCCUCGUAGUUCUCCaa	GGAGAACUACGAGGAGUAU	-3.3	-1.1	-0.3	3	5	2	-38.2	68.7	9.7	6	Ib	47.4	69	56.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0841	NM_014501	Huesken	UBE2S	27338	UCGUAGUUCUCCAAGAGCAgg	UGCUCUUGGAGAACUACGA	-2.1	-2.4	-0.1	2	0	2	-38.8	60.3	-8.3	6	II	47.4	58.1	77.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0842	NM_014501	Huesken	UBE2S	27338	GUAGUUCUCCAAGAGCAGGcg	CCUGCUCUUGGAGAACUAC	-3.3	-2.2	-0.5	1	2	2	-39.4	53.4	2.3	3	II	52.6	51.5	70.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0843	NM_014501	Huesken	UBE2S	27338	UAGUUCUCCAAGAGCAGGCgg	GCCUGCUCUUGGAGAACUA	-3.4	-1.3	-0.7	1	4	3	-40.6	74	7.1	8	Ia	52.6	74.5	76	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0844	NM_014501	Huesken	UBE2S	27338	UCUCCAAGAGCAGGCGGCCcg	GGCCGCCUGCUCUUGGAGA	-3.3	-2.4	-0.7	0	4	7	-46.5	34.9	5.1	4	Ib	68.4	56.1	69.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0845	NM_014501	Huesken	UBE2S	27338	AGGCGGCCCGCCUCCUCGUug	ACGAGGAGGCGGGCCGCCU	-2.2	-2.1	-5.4	3	1	11	-50.5	27.4	-8.7	0	II	78.9	39.7	44.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0846	NM_014501	Huesken	UBE2S	27338	CCGCCUCCUCGUUGAGUGCag	GCACUCAACGAGGAGGCGG	-3.4	-3.3	-2.3	-1	-1	5	-44.5	43.7	8.4	-1	II	68.4	35.1	48.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0847	NM_014501	Huesken	UBE2S	27338	CCUCGUUGAGUGCAGACUCgg	GAGUCUGCACUCAACGAGG	-2.4	-3.3	-2.9	1	0	2	-40.9	46.9	7.8	0	II	57.9	48.2	71.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0848	NM_014501	Huesken	UBE2S	27338	CUCGUUGAGUGCAGACUCGgg	CGAGUCUGCACUCAACGAG	-2.4	-2.1	-3.2	-1	0	2	-40	45.7	-6.9	2	II	57.9	48.9	70.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0849	NM_014501	Huesken	UBE2S	27338	GAGUGCAGACUCGGGGUUAgg	UAACCCCGAGUCUGCACUC	-1.3	-2.4	-1.5	-1	-3	5	-42.2	36.5	-6.1	2	III	57.9	28.4	39.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0850	NM_014501	Huesken	UBE2S	27338	GACUCGGGGUUAGGGUGGAuc	UCCACCCUAACCCCGAGUC	-2.4	-2.4	2.3	0	-1	5	-44.5	27.2	-3.8	2	III	63.2	23.5	39.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0851	NM_014501	Huesken	UBE2S	27338	GGGUGGAUCAGCAGGCACUug	AGUGCCUGCUGAUCCACCC	-2.1	-3.3	0.1	0	-2	3	-45	39.4	-8.9	2	III	63.2	37.7	55.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0852	NM_014501	Huesken	UBE2S	27338	GUGGAUCAGCAGGCACUUGau	CAAGUGCCUGCUGAUCCAC	-2.1	-2.2	-0.2	1	0	3	-41.4	41.9	5	2	II	57.9	41.3	63.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0853	NM_014501	Huesken	UBE2S	27338	GAUGGUCAGCAGUACGUGUcg	ACACGUACUGCUGACCAUC	-2.2	-2.4	1.7	1	0	2	-39.9	53.2	-1.7	3	III	52.6	39.9	59.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0854	NM_014501	Huesken	UBE2S	27338	AUGGUCAGCAGUACGUGUCgg	GACACGUACUGCUGACCAU	-2.4	-1.1	1.7	2	3	2	-39.9	67.5	7.8	6	Ib	52.6	65.4	85.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0855	NM_014501	Huesken	UBE2S	27338	GGAUGCCCAGCUCAGCCGUcc	ACGGCUGAGCUGGGCAUCC	-2.2	-3.3	-3	0	0	4	-46.5	36.4	-0.9	0	III	68.4	30.1	52.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0856	NM_014501	Huesken	UBE2S	27338	CCUCUUGAGCACGUUGACGca	CGUCAACGUGCUCAAGAGG	-2.4	-3.3	0.7	1	1	2	-39.7	51.7	0.3	2	II	57.9	47	63.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0857	NM_014501	Huesken	UBE2S	27338	UCUUGAGCACGUUGACGCAga	UGCGUCAACGUGCUCAAGA	-2.1	-2.4	-1.6	-1	1	3	-39.8	54.3	-0.7	5	II	52.6	45.5	74.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0858	NM_014501	Huesken	UBE2S	27338	CUUGAGCACGUUGACGCAGau	CUGCGUCAACGUGCUCAAG	-2.1	-2.1	-1.6	0	1	3	-39.5	41.3	3.7	1	II	57.9	46.6	67.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0859	NM_014501	Huesken	UBE2S	27338	GUUGACGCAGAUCUCGCCAuu	UGGCGAGAUCUGCGUCAAC	-2.1	-2.2	-4.2	0	1	4	-41.4	54.1	9	2	III	57.9	42	85.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0860	NM_014501	Huesken	UBE2S	27338	UCUCGCCAUUGGCGCCCACgu	GUGGGCGCCAAUGGCGAGA	-2.2	-2.4	-4.7	0	3	7	-45.6	38.3	9.8	2	II	68.4	45.1	54.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0861	NM_014501	Huesken	UBE2S	27338	CAUUGGCGCCCACGUUCGGgu	CCGAACGUGGGCGCCAAUG	-3.3	-2.1	-0.7	-1	2	7	-43.2	36.3	-2	2	II	68.4	39.2	44.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0862	NM_014501	Huesken	UBE2S	27338	CCACGUUCGGGUGGAAGAUcu	AUCUUCCACCCGAACGUGG	-1.1	-3.3	-3.2	1	-2	4	-41	35.4	-3	0	III	57.9	29.3	31.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0863	NM_014501	Huesken	UBE2S	27338	CGUUCGGGUGGAAGAUCUUgg	AAGAUCUUCCACCCGAACG	-0.9	-2.4	1.2	-2	-2	4	-38.8	41.2	-8.6	3	III	52.6	32.1	60.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0864	NM_014501	Huesken	UBE2S	27338	UCUUGGUCAGGAAGUAGCCcu	GGCUACUUCCUGACCAAGA	-3.3	-2.4	0.4	0	4	3	-40.6	59.5	4.8	6	Ib	52.6	65.4	91.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0865	NM_014501	Huesken	UBE2S	27338	AGGAAGUAGCCCUUGGGUGgg	CACCCAAGGGCUACUUCCU	-2.1	-2.1	-3.5	3	3	4	-42.4	54.3	0.3	3	Ib	57.9	53.9	81.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0866	NM_014501	Huesken	UBE2S	27338	GGAAGUAGCCCUUGGGUGGgg	CCACCCAAGGGCUACUUCC	-3.3	-3.3	-1.8	0	1	4	-43.6	48.1	0.7	2	II	63.2	42.5	54.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0867	NM_014501	Huesken	UBE2S	27338	AGUAGCCCUUGGGUGGGGAgg	UCCCCACCCAAGGGCUACU	-2.4	-2.1	-3.4	1	2	4	-46	43.1	-1.4	2	II	63.2	34.5	48.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0868	NM_014501	Huesken	UBE2S	27338	AGCCCUUGGGUGGGGAGGCag	GCCUCCCCACCCAAGGGCU	-3.4	-2.1	-3.7	3	3	4	-49.2	32.5	7.4	1	II	73.7	47.4	46.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0869	NM_014501	Huesken	UBE2S	27338	GGGGAGGCAGGGAAGUCCUuc	AGGACUUCCCUGCCUCCCC	-2.1	-3.3	-1.5	0	-1	4	-47.3	26.1	-3.9	0	III	68.4	34.5	55.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0870	NM_014501	Huesken	UBE2S	27338	CAGGGAAGUCCUUCCCCAGca	CUGGGGAAGGACUUCCCUG	-2.1	-2.1	-8	-1	0	4	-43.6	42.3	-1.3	0	II	63.2	44	40.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0871	NM_014501	Huesken	UBE2S	27338	AGGGAAGUCCUUCCCCAGCag	GCUGGGGAAGGACUUCCCU	-3.4	-2.1	-7.3	2	2	4	-44.9	45.9	15.5	2	II	63.2	54.8	53.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0872	NM_014501	Huesken	UBE2S	27338	UUCCCCAGCAGGAGUUUCAug	UGAAACUCCUGCUGGGGAA	-2.1	-0.9	-4.9	1	0	4	-41.3	62.8	-6.3	6	II	52.6	57	54	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0873	NM_014501	Huesken	UBE2S	27338	GAGUUUCAUGCGGAACAGAcc	UCUGUUCCGCAUGAAACUC	-2.4	-2.4	1	0	-2	4	-37.4	48.8	-6.1	3	II	47.4	35.5	42.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0874	NM_014501	Huesken	UBE2S	27338	CAUGCGGAACAGACCUCCAgc	UGGAGGUCUGUUCCGCAUG	-2.1	-2.1	-2.7	-1	-1	4	-41.9	44.9	-6	1	III	57.9	42	58.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0875	NM_014501	Huesken	UBE2S	27338	GACCUCCAGCAUAUGGGGUcc	ACCCCAUAUGCUGGAGGUC	-2.2	-2.4	-1.5	2	1	4	-43.1	51	1.1	0	III	57.9	33.5	49.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0876	NM_014501	Huesken	UBE2S	27338	CCAGCAUAUGGGGUCCCCUca	AGGGGACCCCAUAUGCUGG	-2.1	-3.3	-2.8	0	0	4	-45.1	39	-3.6	0	III	63.2	41.3	36.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0877	NM_014501	Huesken	UBE2S	27338	CAUAUGGGGUCCCCUCAGGgc	CCUGAGGGGACCCCAUAUG	-3.3	-2.1	-2.8	0	1	4	-44.1	47.6	-4.3	3	II	63.2	48.1	25.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0878	NM_014501	Huesken	UBE2S	27338	AUAUGGGGUCCCCUCAGGGcc	CCCUGAGGGGACCCCAUAU	-3.3	-1.1	-3.9	1	6	4	-45.3	49.3	0	4	Ib	63.2	61.7	46.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0879	NM_014501	Huesken	UBE2S	27338	GGGUCCCCUCAGGGCCCUCga	GAGGGCCCUGAGGGGACCC	-2.4	-3.3	-4.1	-1	0	6	-50.9	27.3	9.7	-1	II	78.9	28.4	44.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0880	NM_014501	Huesken	UBE2S	27338	UCAGGGCCCUCGAUGGUGAcc	UCACCAUCGAGGGCCCUGA	-2.4	-2.4	-1	1	1	6	-45.7	40.3	-6.4	3	II	63.2	46.8	35.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0881	NM_014501	Huesken	UBE2S	27338	CAGGGCCCUCGAUGGUGACcu	GUCACCAUCGAGGGCCCUG	-2.2	-2.1	-1	-2	0	6	-45.5	35.1	5.4	-1	II	68.4	33.7	45.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0882	NM_014501	Huesken	UBE2S	27338	UGAGGUCCUCCUCGUUGGGaa	CCCAACGAGGAGGACCUCA	-3.3	-2.1	-5.3	-1	4	3	-44.3	48.2	3.1	2	II	63.2	53.7	54	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0883	NM_014501	Huesken	UBE2S	27338	GAGGUCCUCCUCGUUGGGAaa	UCCCAACGAGGAGGACCUC	-2.4	-2.4	-3.6	1	0	3	-44.6	41.2	-3.8	0	III	63.2	31.5	35.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0884	NM_014501	Huesken	UBE2S	27338	AGGUCCUCCUCGUUGGGAAag	UUCCCAACGAGGAGGACCU	-0.9	-2.1	-2.2	3	0	3	-43.1	60.5	-3.8	2	II	57.9	36.3	41.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0885	NM_014501	Huesken	UBE2S	27338	GUCCUCCUCGUUGGGAAAGac	CUUUCCCAACGAGGAGGAC	-2.1	-2.2	-2.8	1	0	3	-40.7	47.5	3	0	II	57.9	36.2	33.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0886	NM_014501	Huesken	UBE2S	27338	CCUCGUUGGGAAAGACCUUga	AAGGUCUUUCCCAACGAGG	-0.9	-3.3	-0.8	1	-2	3	-39.2	37.4	-6.3	2	III	52.6	35.4	53	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0887	NM_014501	Huesken	UBE2S	27338	UGGGAAAGACCUUGAUGCCau	GGCAUCAAGGUCUUUCCCA	-3.3	-2.1	-1.2	-1	3	3	-40.3	54.3	10.8	4	Ib	52.6	59.1	57.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0888	NM_014501	Huesken	UBE2S	27338	GGAAAGACCUUGAUGCCAUcg	AUGGCAUCAAGGUCUUUCC	-1.1	-3.3	-1.2	1	0	3	-38.1	49.6	-1.5	3	II	47.4	38.6	56.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0889	NM_014501	Huesken	UBE2S	27338	GACCUUGAUGCCAUCGGGUgg	ACCCGAUGGCAUCAAGGUC	-2.2	-2.4	0	1	1	4	-42.1	47.3	-8.9	2	III	57.9	41.6	66.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0890	NM_014501	Huesken	UBE2S	27338	CCUUGAUGCCAUCGGGUGGgu	CCACCCGAUGGCAUCAAGG	-3.3	-3.3	-0.3	0	0	4	-42.9	50	5.7	3	II	63.2	39.1	47.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0891	NM_014501	Huesken	UBE2S	27338	UGAUGCCAUCGGGUGGGUCug	GACCCACCCGAUGGCAUCA	-2.4	-2.1	-0.6	0	4	4	-44.5	51.2	9.7	4	II	63.2	54.3	61.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0892	NM_014501	Huesken	UBE2S	27338	GCCAUCGGGUGGGUCUGCGgu	CGCAGACCCACCCGAUGGC	-2.4	-3.4	-0.6	1	2	4	-46.8	35.7	2.3	2	II	73.7	35	51.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0893	NM_014501	Huesken	UBE2S	27338	GGGUGGGUCUGCGGUCAGUgu	ACUGACCGCAGACCCACCC	-2.2	-3.3	-1.5	0	-2	4	-46.4	27.5	-6.3	0	III	68.4	24.4	43.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0894	NM_014501	Huesken	UBE2S	27338	UGCGGUCAGUGUCGUCACCuc	GGUGACGACACUGACCGCA	-3.3	-2.1	-2.1	0	2	4	-43.5	49.1	12.8	1	II	63.2	52.9	88.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0895	NM_004223	Huesken	UBE2L6	9246	UCCGAAUCGGAGGGUGAACuc	GUUCACCCUCCGAUUCGGA	-2.2	-2.4	-2	1	1	3	-41.5	44.4	12.4	3	Ib	57.9	49.5	61.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0896	NM_004223	Huesken	UBE2L6	9246	CCGAAUCGGAGGGUGAACUcu	AGUUCACCCUCCGAUUCGG	-2.1	-3.3	-0.1	0	-2	3	-41.2	46.3	-0.9	2	III	57.9	39.2	55.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0897	NM_004223	Huesken	UBE2L6	9246	CGGAGGGUGAACUCUUCGGca	CCGAAGAGUUCACCCUCCG	-3.3	-2.4	-1.1	0	0	3	-42.2	49.2	-2.1	1	II	63.2	46.8	62.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0898	NM_004223	Huesken	UBE2L6	9246	GAGGGUGAACUCUUCGGCAuu	UGCCGAAGAGUUCACCCUC	-2.1	-2.4	-0.3	0	0	4	-42	44.8	-3.8	1	III	57.9	40.2	59.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0899	NM_004223	Huesken	UBE2L6	9246	GGGUGAACUCUUCGGCAUUcu	AAUGCCGAAGAGUUCACCC	-0.9	-3.3	0.9	-1	-3	4	-39.5	43.4	1.5	2	III	52.6	29.2	51.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0900	NM_004223	Huesken	UBE2L6	9246	CUUCGGCAUUCUUUCUGAAca	UUCAGAAAGAAUGCCGAAG	-0.9	-2.1	0.7	0	-1	4	-34.8	60.9	-2.8	2	III	42.1	32.8	57.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0901	NM_004223	Huesken	UBE2L6	9246	AUUCUUUCUGAACAGCUCCgg	GGAGCUGUUCAGAAAGAAU	-3.3	-1.1	-0.3	3	4	2	-35.8	81.5	12.1	7	Ia	42.1	76	107.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0902	NM_004223	Huesken	UBE2L6	9246	AACAGCUCCGGAUUCUGUGuc	CACAGAAUCCGGAGCUGUU	-2.1	-0.9	-1.2	3	4	4	-39.5	70.4	2.3	4	Ib	52.6	61.2	97.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0903	NM_004223	Huesken	UBE2L6	9246	ACAGCUCCGGAUUCUGUGUca	ACACAGAAUCCGGAGCUGU	-2.2	-2.2	-1.1	2	1	4	-40.8	63	1.4	3	II	52.6	47.5	85.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0904	NM_004223	Huesken	UBE2L6	9246	AGCUCCGGAUUCUGUGUCAgc	UGACACAGAAUCCGGAGCU	-2.1	-2.1	2.6	0	-1	4	-41	55.2	-6.1	5	II	52.6	37.8	54.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0905	NM_004223	Huesken	UBE2L6	9246	GCUCCGGAUUCUGUGUCAGca	CUGACACAGAAUCCGGAGC	-2.1	-3.4	0.4	1	2	4	-41	45.8	3	1	II	57.9	32.6	79.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0906	NM_004223	Huesken	UBE2L6	9246	GUCAGCAGGUCAGCGAGGUcc	ACCUCGCUGACCUGCUGAC	-2.2	-2.2	-1.5	1	0	3	-44.3	34.5	-6.3	1	III	63.2	34.8	58.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0907	NM_004223	Huesken	UBE2L6	9246	GCAGGUCAGCGAGGUCCAUcc	AUGGACCUCGCUGACCUGC	-1.1	-3.4	-0.3	0	-1	3	-44.4	19.9	-4	0	III	63.2	19.9	43.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0908	NM_004223	Huesken	UBE2L6	9246	AGGUCAGCGAGGUCCAUCCgc	GGAUGGACCUCGCUGACCU	-3.3	-2.1	0	2	2	3	-44.6	59.9	7.4	5	II	63.2	58.7	80.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0909	NM_004223	Huesken	UBE2L6	9246	GGUCAGCGAGGUCCAUCCGca	CGGAUGGACCUCGCUGACC	-2.4	-3.3	-0.3	1	2	3	-44.9	37.6	8.1	1	II	68.4	36	71.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0910	NM_004223	Huesken	UBE2L6	9246	AGCGAGGUCCAUCCGCAGGgg	CCUGCGGAUGGACCUCGCU	-3.3	-2.1	-3.1	2	2	4	-45.8	45	10.4	2	II	68.4	50.4	81.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0911	NM_004223	Huesken	UBE2L6	9246	GCGAGGUCCAUCCGCAGGGgc	CCCUGCGGAUGGACCUCGC	-3.3	-3.4	-1.9	1	1	4	-47	31.1	0.1	1	II	73.7	42.4	59.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0912	NM_004223	Huesken	UBE2L6	9246	GGUCCAUCCGCAGGGGCUCcc	GAGCCCCUGCGGAUGGACC	-2.4	-3.3	-0.8	2	1	5	-47.9	27.8	5.1	1	II	73.7	33.9	55.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0913	NM_004223	Huesken	UBE2L6	9246	CCAUCCGCAGGGGCUCCCUga	AGGGAGCCCCUGCGGAUGG	-2.1	-3.3	-3.2	-1	-1	5	-48.7	33.8	-6	1	III	73.7	34.7	60.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0914	NM_004223	Huesken	UBE2L6	9246	GGGGCUCCCUGAUAUUCGGuc	CCGAAUAUCAGGGAGCCCC	-3.3	-3.3	-1.6	1	1	5	-43.5	46.6	0	-2	II	63.2	37	50	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0915	NM_004223	Huesken	UBE2L6	9246	UGAUAUUCGGUCUAUUCACca	GUGAAUAGACCGAAUAUCA	-2.2	-2.1	1.5	2	3	3	-33.7	82.1	7.8	7	Ia	36.8	70.7	89.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0916	NM_004223	Huesken	UBE2L6	9246	CGGUCUAUUCACCAGCACAuu	UGUGCUGGUGAAUAGACCG	-2.1	-2.4	-2.5	-1	-4	3	-39.7	58.4	-3.4	1	III	52.6	40.7	59	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0917	NM_004223	Huesken	UBE2L6	9246	CUAUUCACCAGCACAUUGAgg	UCAAUGUGCUGGUGAAUAG	-2.4	-2.1	1.2	0	-2	2	-35.9	71.5	-10.7	7	II	42.1	51	69.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0918	NM_004223	Huesken	UBE2L6	9246	GCACAUUGAGGGCCUCCAGga	CUGGAGGCCCUCAAUGUGC	-2.1	-3.4	-0.5	2	1	5	-43.7	42.1	5.1	2	II	63.2	37.4	48.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0919	NM_004223	Huesken	UBE2L6	9246	ACAUUGAGGGCCUCCAGGAcu	UCCUGGAGGCCCUCAAUGU	-2.4	-2.2	-0.5	2	1	5	-43.9	47.3	-8.5	5	II	57.9	47.7	74.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0920	NM_004223	Huesken	UBE2L6	9246	CCUCCAGGACUUGGCAAGUcu	ACUUGCCAAGUCCUGGAGG	-2.2	-3.3	-1.6	-1	-2	3	-42.3	34.4	-3	0	III	57.9	29.9	31.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0921	NM_004223	Huesken	UBE2L6	9246	UGGCAAGUCUUGGUGCAAGgc	CUUGCACCAAGACUUGCCA	-2.1	-2.1	-0.9	2	2	3	-39.7	51.9	5	5	II	52.6	54	89.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0922	NM_004223	Huesken	UBE2L6	9246	UCUUGGUGCAAGGCUUCCAgu	UGGAAGCCUUGCACCAAGA	-2.1	-2.4	-0.8	2	1	3	-41.1	62.2	-1.5	7	II	52.6	57	77.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0923	NM_004223	Huesken	UBE2L6	9246	UGGUGCAAGGCUUCCAGUUcu	AACUGGAAGCCUUGCACCA	-0.9	-2.1	0.4	1	0	3	-40.9	61.6	-3.3	5	II	52.6	54.6	77.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0924	NM_004223	Huesken	UBE2L6	9246	CUUCCAGUUCUCACUGCUGau	CAGCAGUGAGAACUGGAAG	-2.1	-2.1	-3.7	0	1	2	-39	53.8	-6.9	2	II	52.6	50.3	74.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0925	NM_004223	Huesken	UBE2L6	9246	UCCAGUUCUCACUGCUGAUga	AUCAGCAGUGAGAACUGGA	-1.1	-2.4	-3.7	0	0	2	-39.5	66.3	-4	4	II	47.4	49.8	82.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0926	NM_004223	Huesken	UBE2L6	9246	CCAGUUCUCACUGCUGAUGau	CAUCAGCAGUGAGAACUGG	-2.1	-3.3	-3.7	0	-1	2	-39.2	57.6	-1.3	2	II	52.6	46.3	65.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0927	NM_004223	Huesken	UBE2L6	9246	CAGUUCUCACUGCUGAUGAug	UCAUCAGCAGUGAGAACUG	-2.4	-2.1	-2.4	0	-2	2	-38.3	70.2	-1	4	II	47.4	44.8	61.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0928	NM_004223	Huesken	UBE2L6	9246	UCUCACUGCUGAUGAUGGGca	CCCAUCAUCAGCAGUGAGA	-3.3	-2.4	-1.1	2	4	3	-40.8	58	2.7	5	Ib	52.6	55.8	74	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0929	NM_004223	Huesken	UBE2L6	9246	GAUGAUGGGCAGGCAAAUCug	GAUUUGCCUGCCCAUCAUC	-2.4	-2.4	1.2	1	1	4	-39.5	48.6	12.4	4	II	52.6	46.9	71.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0930	NM_004223	Huesken	UBE2L6	9246	CUCGUCCACGUUGGGGUGGua	CCACCCCAACGUGGACGAG	-3.3	-2.1	-4.2	-1	0	4	-44.2	38.9	1	1	II	68.4	41.6	67.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0931	NM_004223	Huesken	UBE2L6	9246	UCGUCCACGUUGGGGUGGUag	ACCACCCCAACGUGGACGA	-2.2	-2.4	-4.7	0	1	4	-44.3	42.6	-4	3	II	63.2	44.4	64.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0932	NM_004223	Huesken	UBE2L6	9246	CGUCCACGUUGGGGUGGUAga	UACCACCCCAACGUGGACG	-1.3	-2.4	-4.7	-1	-3	4	-43.2	25.8	-5.8	-1	III	63.2	13.8	37.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0933	NM_004223	Huesken	UBE2L6	9246	UCCACGUUGGGGUGGUAGAuc	UCUACCACCCCAACGUGGA	-2.4	-2.4	-4.7	1	-1	4	-43.1	56	-3.8	3	II	57.9	45.8	53	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0934	NM_004223	Huesken	UBE2L6	9246	UGGGGUGGUAGAUCUUGGUug	ACCAAGAUCUACCACCCCA	-2.2	-2.1		0	1	4	-41.7	58.1	-4	5	II	52.6	55.9	90.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0935	NM_004223	Huesken	UBE2L6	9246	GGGGUGGUAGAUCUUGGUUgu	AACCAAGAUCUACCACCCC	-0.9	-3.3		0	-1	4	-40.5	54.2	6.1	2	III	52.6	33.3	43.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0936	NM_004223	Huesken	UBE2L6	9246	GUGGUAGAUCUUGGUUGUGaa	CACAACCAAGAUCUACCAC	-2.1	-2.2		-1	1	2	-37	47.6	3	3	II	47.4	41.2	45.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0937	NM_004223	Huesken	UBE2L6	9246	GUAGAUCUUGGUUGUGAAUuu	AUUCACAACCAAGAUCUAC	-1.1	-2.2	1.4	-1	-1	2	-33.8	66.6	1.8	3	II	36.8	37	51	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0938	NM_004223	Huesken	UBE2L6	9246	GAUCUUGGUUGUGAAUUUGau	CAAAUUCACAACCAAGAUC	-2.1	-2.4	1.4	1	1	2	-32.1	70.4	3	5	II	36.8	48.2	85.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0939	NM_004223	Huesken	UBE2L6	9246	UUGUGAAUUUGAUCAUGGGag	CCCAUGAUCAAAUUCACAA	-3.3	-0.9	-0.5	0	4	3	-33.4	78.4	0	6	Ia	36.8	68.6	95.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0940	NM_004223	Huesken	UBE2L6	9246	UUGAUCAUGGGAGGCUUGAac	UCAAGCCUCCCAUGAUCAA	-2.4	-0.9	1.5	0	0	3	-39.5	62.5	-3.8	8	II	47.4	58	86.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0941	NM_004223	Huesken	UBE2L6	9246	UGAUCAUGGGAGGCUUGAAcg	UUCAAGCCUCCCAUGAUCA	-0.9	-2.1	1.3	2	0	3	-39.5	60	-1.5	6	II	47.4	44.7	71.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0942	NM_004223	Huesken	UBE2L6	9246	GGAGGCUUGAACGGAUACUcc	AGUAUCCGUUCAAGCCUCC	-2.1	-3.3	1.4	1	-1	3	-39.9	44.8	-4	3	III	52.6	37.9	53.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0943	NM_004223	Huesken	UBE2L6	9246	AGGCUUGAACGGAUACUCCgg	GGAGUAUCCGUUCAAGCCU	-3.3	-2.1	-1.5	2	3	3	-39.9	60	7.1	4	II	52.6	59.9	84.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0944	NM_004223	Huesken	UBE2L6	9246	ACGGAUACUCCGGCGGGAAgc	UUCCCGCCGGAGUAUCCGU	-0.9	-2.2	-3.1	1	-1	8	-44.1	32.3	-3.4	2	II	63.2	34.7	43	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0945	NM_004223	Huesken	UBE2L6	9246	CGGAUACUCCGGCGGGAAGcu	CUUCCCGCCGGAGUAUCCG	-2.1	-2.4	-2.5	-1	-2	8	-44	37.1	0.4	0	II	68.4	28.2	38.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0946	NM_004223	Huesken	UBE2L6	9246	ACUCCGGCGGGAAGCUGAUgc	AUCAGCUUCCCGCCGGAGU	-1.1	-2.2	-2.5	2	1	8	-44.6	31.1	-6.6	2	II	63.2	34.7	52.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0947	NM_004223	Huesken	UBE2L6	9246	GGGAAGCUGAUGCGCAGGUug	ACCUGCGCAUCAGCUUCCC	-2.2	-3.3	-1.4	0	-1	4	-44.1	32.1	1.1	1	III	63.2	30.6	70.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0948	NM_004223	Huesken	UBE2L6	9246	GGAAGCUGAUGCGCAGGUUga	AACCUGCGCAUCAGCUUCC	-0.9	-3.3	-1.4	1	-1	4	-41.7	39.5	-6.3	1	III	57.9	29.6	51.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0949	NM_004223	Huesken	UBE2L6	9246	UGCGCAGGUUGAAGGCUUUca	AAAGCCUUCAACCUGCGCA	-0.9	-2.1	0.3	-1	-1	4	-40	45.1	-6.6	5	II	52.6	43.9	69.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0950	NM_004223	Huesken	UBE2L6	9246	GUAGGGAGGUUGGUCGGGUag	ACCCGACCAACCUCCCUAC	-2.2	-2.2	1.7	1	2	4	-44.3	29.9	-1.6	2	III	63.2	39.9	64	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0951	NM_004223	Huesken	UBE2L6	9246	GGGAGGUUGGUCGGGUAGGag	CCUACCCGACCAACCUCCC	-3.3	-3.3	1.7	1	0	4	-45.4	30.3	-2.4	1	II	68.4	37.8	55.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0952	NM_004223	Huesken	UBE2L6	9246	GAGGUUGGUCGGGUAGGAGga	CUCCUACCCGACCAACCUC	-2.1	-2.4	2	0	2	4	-43.3	41.1	2.3	2	II	63.2	38.3	63.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0953	NM_004223	Huesken	UBE2L6	9246	GGUUGGUCGGGUAGGAGGAga	UCCUCCUACCCGACCAACC	-2.4	-3.3	2	1	-1	4	-44.5	38.2	-3.3	2	III	63.2	28.1	49.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0954	NM_004223	Huesken	UBE2L6	9246	UUGGUCGGGUAGGAGGAGAgc	UCUCCUCCUACCCGACCAA	-2.4	-0.9	2	1	0	4	-43.5	46.1	-1.5	5	II	57.9	52.4	79.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0955	NM_004223	Huesken	UBE2L6	9246	GUCGGGUAGGAGGAGAGCGug	CGCUCUCCUCCUACCCGAC	-2.4	-2.2	2	2	2	4	-45.1	33	2.3	1	II	68.4	47.7	73.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0956	NM_004223	Huesken	UBE2L6	9246	GGUAGGAGGAGAGCGUGCCac	GGCACGCUCUCCUCCUACC	-3.3	-3.3	0.6	1	2	3	-45.8	37	7.4	3	II	68.4	44.9	62.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0957	NM_004223	Huesken	UBE2L6	9246	UAGGAGGAGAGCGUGCCACac	GUGGCACGCUCUCCUCCUA	-2.2	-1.3	0.6	1	4	3	-44.6	47.5	10.1	6	II	63.2	64.3	96.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0958	NM_004223	Huesken	UBE2L6	9246	AGGAGAGCGUGCCACACCAgg	UGGUGUGGCACGCUCUCCU	-2.1	-2.1	-2.1	2	0	3	-45.2	35.9	-3.7	2	II	63.2	42.9	89.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0959	NM_004223	Huesken	UBE2L6	9246	GAGCGUGCCACACCAGGACau	GUCCUGGUGUGGCACGCUC	-2.2	-2.4	-2.1	2	1	3	-45.3	36.6	7.5	1	II	68.4	41.7	74.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0960	NM_004223	Huesken	UBE2L6	9246	CAGGACAUUGGCAUCAUCGcu	CGAUGAUGCCAAUGUCCUG	-2.4	-2.1	0.1	-1	1	3	-38.6	61.8	-1.9	4	II	52.6	60.6	97.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0961	NM_004223	Huesken	UBE2L6	9246	AGGACAUUGGCAUCAUCGCug	GCGAUGAUGCCAAUGUCCU	-3.4	-2.1	0.1	3	3	3	-39.9	61.2	5.1	4	Ib	52.6	57.3	107.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0962	NM_004223	Huesken	UBE2L6	9246	GGACAUUGGCAUCAUCGCUgg	AGCGAUGAUGCCAAUGUCC	-2.1	-3.3	-0.1	3	0	3	-39.9	52.3	6.5	3	II	52.6	40.8	87.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0963	NM_004223	Huesken	UBE2L6	9246	GGCAUCAUCGCUGGACAGGuu	CCUGUCCAGCGAUGAUGCC	-3.3	-3.3	-0.1	0	0	3	-43.3	43.4	0.7	2	II	63.2	37.8	77.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0964	NM_004223	Huesken	UBE2L6	9246	CGCUGGACAGGUUCCGCAGgu	CUGCGGAACCUGUCCAGCG	-2.1	-2.4	-2.4	-1	-1	4	-44.2	45.4	1	0	II	68.4	37.3	76.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0965	NM_004223	Huesken	UBE2L6	9246	CUGGACAGGUUCCGCAGGUau	ACCUGCGGAACCUGUCCAG	-2.2	-2.1	-2.4	-1	-1	4	-43.9	31.7	-3.2	1	III	63.2	38.7	73.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0966	NM_004223	Huesken	UBE2L6	9246	ACAGGUUCCGCAGGUAUGGgg	CCAUACCUGCGGAACCUGU	-3.3	-2.2	-0.3	2	3	4	-41.8	44.6	-2.4	4	Ib	57.9	55.9	88.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0967	NM_016406	Huesken	Ufc1	51506	AUUUCUCUUUGUGUUGGAUga	AUCCAACACAAAGAGAAAU	-1.1	-1.1	2.4	1	3	2	-32.1	88.6	1.4	5	II	31.6	48.7	69.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0968	NM_016406	Huesken	Ufc1	51506	UUCUCUUUGUGUUGGAUGAcg	UCAUCCAACACAAAGAGAA	-2.4	-0.9	2.4	1	0	2	-34.6	91.1	-0.7	7	II	36.8	58.8	93	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0969	NM_016406	Huesken	Ufc1	51506	CUCUUUGUGUUGGAUGACGcc	CGUCAUCCAACACAAAGAG	-2.4	-2.1	1	0	0	2	-35.9	62.9	-2	4	II	47.4	54.2	86.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0970	NM_016406	Huesken	Ufc1	51506	UUGUGUUGGAUGACGCCCUuc	AGGGCGUCAUCCAACACAA	-2.1	-0.9	-3.4	2	2	5	-40.5	65.1	-6.6	6	II	52.6	71.8	107.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0971	NM_016406	Huesken	Ufc1	51506	CCCUUCUGAAUCAGAUCAGgg	CUGAUCUGAUUCAGAAGGG	-2.1	-3.3	-3.4	-1	-1	3	-37.3	56.3	-6.9	3	II	47.4	40.7	73.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0972	NM_016406	Huesken	Ufc1	51506	UGAAUCAGAUCAGGGAUUUcc	AAAUCCCUGAUCUGAUUCA	-0.9	-2.1	0.2	-1	0	3	-35.1	64.7	-6.3	8	II	36.8	55.2	81	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0973	NM_016406	Huesken	Ufc1	51506	UCAGGGAUUUCCACUGCCAgc	UGGCAGUGGAAAUCCCUGA	-2.1	-2.4	-0.6	0	1	3	-41.5	48	-11	5	II	52.6	56.7	71.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0974	NM_016406	Huesken	Ufc1	51506	AGGGAUUUCCACUGCCAGCca	GCUGGCAGUGGAAAUCCCU	-3.4	-2.1	-0.6	2	2	3	-42.5	57.9	10.1	3	Ib	57.9	58.4	48.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0975	NM_016406	Huesken	Ufc1	51506	ACUGCCAGCCAUGGACCCAgc	UGGGUCCAUGGCUGGCAGU	-2.1	-2.2	-1.3	1	1	3	-45.9	38.8	1.6	2	II	63.2	40.1	35.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0976	NM_016406	Huesken	Ufc1	51506	CUGCCAGCCAUGGACCCAGcc	CUGGGUCCAUGGCUGGCAG	-2.1	-2.1	-1.3	1	0	3	-45.8	33.3	-2	1	II	68.4	45.7	60.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0977	NM_016406	Huesken	Ufc1	51506	UGGACCCAGCCCCAGAGCCau	GGCUCUGGGGCUGGGUCCA	-3.3	-2.1	-4.6	1	3	5	-49.5	44.1	5.1	2	II	73.7	58	69.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0978	NM_016406	Huesken	Ufc1	51506	AGCCCCAGAGCCAUGAGAUga	AUCUCAUGGCUCUGGGGCU	-1.1	-2.1	-3.4	2	1	5	-44.1	47.6	-8.9	1	II	57.9	39.7	53.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0979	NM_016406	Huesken	Ufc1	51506	AGCCAUGAGAUGAGCUAGUcc	ACUAGCUCAUCUCAUGGCU	-2.2	-2.1	-1.7	2	0	3	-39.8	47	-3.9	4	II	47.4	47.1	53.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0980	NM_016406	Huesken	Ufc1	51506	CCAUGAGAUGAGCUAGUCCaa	GGACUAGCUCAUCUCAUGG	-3.3	-3.3	1.3	-1	1	2	-40	53.7	12.4	4	II	52.6	49.2	61.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0981	NM_016406	Huesken	Ufc1	51506	UCCAAAUUUGGGCACAUUCcu	GAAUGUGCCCAAAUUUGGA	-2.4	-2.4	-1.5	1	1	4	-35.4	74.7	12.5	6	Ia	42.1	67	67.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0982	NM_016406	Huesken	Ufc1	51506	AUUUGGGCACAUUCCUGGCcc	GCCAGGAAUGUGCCCAAAU	-3.4	-1.1	-0.8	1	5	4	-40	70.9	12.7	6	Ib	52.6	63	77.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0983	NM_016406	Huesken	Ufc1	51506	AUUCCUGGCCCACAAAGGUuu	ACCUUUGUGGGCCAGGAAU	-2.2	-1.1	-1.5	3	3	5	-41	53	-3.9	4	II	52.6	53.9	56.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0984	NM_016406	Huesken	Ufc1	51506	ACAAAGGUUUGAAAUGAUCcg	GAUCAUUUCAAACCUUUGU	-2.4	-2.2	0.4	1	2	2	-30.9	66	7.5	6	Ib	31.6	61.1	98.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0985	NM_016406	Huesken	Ufc1	51506	AAGGUUUGAAAUGAUCCGUca	ACGGAUCAUUUCAAACCUU	-2.2	-0.9	-0.3	2	2	3	-33.6	76	1.4	6	II	36.8	63.2	106	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0986	NM_016406	Huesken	Ufc1	51506	AGGUUUGAAAUGAUCCGUCag	GACGGAUCAUUUCAAACCU	-2.4	-2.1	-0.3	1	3	3	-35.1	71.1	7.1	6	Ib	42.1	63.9	122.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0987	NM_016406	Huesken	Ufc1	51506	GUUUGAAAUGAUCCGUCAGgc	CUGACGGAUCAUUUCAAAC	-2.1	-2.2	-0.3	0	2	3	-33.9	69.9	7.7	4	II	42.1	47.1	65.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0988	NM_016406	Huesken	Ufc1	51506	UUGAAAUGAUCCGUCAGGCau	GCCUGACGGAUCAUUUCAA	-3.4	-0.9	-0.4	1	5	3	-37.5	67.8	7.7	7	Ia	47.4	71.4	117.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0989	NM_016406	Huesken	Ufc1	51506	CCGUCAGGCAUAUUUUGCCac	GGCAAAAUAUGCCUGACGG	-3.3	-3.3	-4.7	0	1	3	-38.3	60.9	7.7	2	II	52.6	50.3	99.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0990	NM_016406	Huesken	Ufc1	51506	UGCCACCCCUGUACAUCUUug	AAGAUGUACAGGGGUGGCA	-0.9	-2.1	0.5	2	0	4	-41.5	56.3	-0.8	4	II	52.6	45.4	62.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0991	NM_016406	Huesken	Ufc1	51506	CACCCCUGUACAUCUUUGCug	GCAAAGAUGUACAGGGGUG	-3.4	-2.1	0.5	1	0	4	-39.1	68.9	3.1	4	II	52.6	53.3	108.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0992	NM_016406	Huesken	Ufc1	51506	CCUGUACAUCUUUGCUGUCuu	GACAGCAAAGAUGUACAGG	-2.4	-3.3	-0.1	-2	0	2	-37	54.4	8.4	2	II	47.4	39.6	50.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0993	NM_016406	Huesken	Ufc1	51506	UGUACAUCUUUGCUGUCUUuc	AAGACAGCAAAGAUGUACA	-0.9	-2.1	-0.1	1	2	2	-34.6	81.3	0.8	6	II	36.8	58.5	112.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0994	NM_016406	Huesken	Ufc1	51506	AUCUUUGCUGUCUUUCCAUcc	AUGGAAAGACAGCAAAGAU	-1.1	-1.1	0.3	1	2	2	-34.5	81.4	-4	6	II	36.8	57.4	69.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0995	NM_016406	Huesken	Ufc1	51506	CUUUGCUGUCUUUCCAUCCag	GGAUGGAAAGACAGCAAAG	-3.3	-2.1	0.3	0	1	2	-36.7	79.3	8.4	5	II	47.4	63.4	102.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0996	NM_016406	Huesken	Ufc1	51506	UCUUUCCAUCCAGCUCAGGaa	CCUGAGCUGGAUGGAAAGA	-3.3	-2.4	-1	0	3	2	-40.5	60.5	-2.4	5	Ib	52.6	57.6	120.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0997	NM_016406	Huesken	Ufc1	51506	CAUCCAGCUCAGGAACUGCaa	GCAGUUCCUGAGCUGGAUG	-3.4	-2.1	-4.4	0	1	2	-41.6	47.5	7.7	2	II	57.9	48.2	80.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0998	NM_016406	Huesken	Ufc1	51506	CCAGCUCAGGAACUGCAAUuu	AUUGCAGUUCCUGAGCUGG	-1.1	-3.3	-4.4	0	-2	2	-40.1	47.1	1.1	0	III	52.6	32.5	61.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC0999	NM_016406	Huesken	Ufc1	51506	GAACUGCAAUUUCUGGGGCag	GCCCCAGAAAUUGCAGUUC	-3.4	-2.4	0.6	1	4	5	-38.9	56.4	15.2	3	II	52.6	46.8	61.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1000	NM_016406	Huesken	Ufc1	51506	AACUGCAAUUUCUGGGGCAgu	UGCCCCAGAAAUUGCAGUU	-2.1	-0.9	-0.1	0	1	5	-38.6	56.7	-6.1	5	II	47.4	47.2	44.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1001	NM_016406	Huesken	Ufc1	51506	UGCAAUUUCUGGGGCAGUAgu	UACUGCCCCAGAAAUUGCA	-1.3	-2.1	-0.1	1	-1	5	-39	60.2	-1.1	6	II	47.4	48.1	52.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1002	NM_016406	Huesken	Ufc1	51506	UGGGGCAGUAGUAGGAUAUgu	AUAUCCUACUACUGCCCCA	-1.1	-2.1	3.5	-1	-1	5	-40	58.8	-3.5	6	II	47.4	51.6	78.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1003	NM_016406	Huesken	Ufc1	51506	CAGUAGUAGGAUAUGUGAUag	AUCACAUAUCCUACUACUG	-1.1	-2.1	3.5	1	-1	2	-34.5	71	1.8	4	II	36.8	44.3	69.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1004	NM_016406	Huesken	Ufc1	51506	AUAUGUGAUAGGAAUGUCAaa	UGACAUUCCUAUCACAUAU	-2.1	-1.1	1	1	1	2	-33.3	75.7	-6.3	8	II	31.6	63.7	114.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1005	NM_016406	Huesken	Ufc1	51506	GAUAGGAAUGUCAAACUCGau	CGAGUUUGACAUUCCUAUC	-2.4	-2.4	0	0	2	2	-34.3	58.2	-4.9	5	II	42.1	60.5	95.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1006	NM_016406	Huesken	Ufc1	51506	UCAAACUCGAUGUCAAACUca	AGUUUGACAUCGAGUUUGA	-2.1	-2.4	0.8	2	1	2	-33.8	77.2	-1.3	8	II	36.8	69.7	121.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1007	NM_016406	Huesken	Ufc1	51506	GAUGUCAAACUCAUAUUUCag	GAAAUAUGAGUUUGACAUC	-2.4	-2.4	1.3	0	2	1	-30.6	77.6	4.8	5	II	31.6	56.4	66.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1008	NM_016406	Huesken	Ufc1	51506	AUGUCAAACUCAUAUUUCAgg	UGAAAUAUGAGUUUGACAU	-2.1	-1.1	1.3	2	0	1	-30.3	82.2	-6.1	6	II	26.3	57.2	75.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1009	NM_016406	Huesken	Ufc1	51506	AACUCAUAUUUCAGGAGGUca	ACCUCCUGAAAUAUGAGUU	-2.2	-0.9	0.2	1	2	2	-34.9	66.1	-8.9	5	II	36.8	51.8	43.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1010	NM_016406	Huesken	Ufc1	51506	CAGGAGGUCAUGGAUAUACca	GUAUAUCCAUGACCUCCUG	-2.2	-2.1	2.7	0	-1	2	-37.9	54.2	8.1	5	II	47.4	53.5	96	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1011	NM_016406	Huesken	Ufc1	51506	GGAGGUCAUGGAUAUACCAgc	UGGUAUAUCCAUGACCUCC	-2.1	-3.3	-1.4	0	-1	2	-39.1	47	-3.8	0	III	47.4	37.2	31.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1012	NM_016406	Huesken	Ufc1	51506	AUAUACCAGCAUUUUCCAAac	UUGGAAAAUGCUGGUAUAU	-0.9	-1.1	1.5	2	2	2	-32.5	80.6	6.6	6	II	31.6	48.6	56.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1013	NM_016406	Huesken	Ufc1	51506	UUUCCAAACCACCGAGUUCcu	GAACUCGGUGGUUUGGAAA	-2.4	-0.9	-1.1	1	3	3	-36.9	67.6	9.8	6	Ia	47.4	65.4	97.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1014	NM_016406	Huesken	Ufc1	51506	CCAAACCACCGAGUUCCUUcc	AAGGAACUCGGUGGUUUGG	-0.9	-3.3	-1.5	0	-1	3	-39	44.7	-0.9	2	III	52.6	34.5	32.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1015	NM_016406	Huesken	Ufc1	51506	AACCACCGAGUUCCUUCCUug	AGGAAGGAACUCGGUGGUU	-2.1	-0.9	0.5	2	2	3	-40.5	56.7	4.2	4	II	52.6	49	61.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1016	NM_016406	Huesken	Ufc1	51506	GUUCCUUCCUUGUUGGACUcc	AGUCCAACAAGGAAGGAAC	-2.1	-2.2	-2.1	3	1	2	-37.8	73.8	-1.6	2	II	47.4	50	83.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1017	NM_016406	Huesken	Ufc1	51506	CUUCCUUGUUGGACUCCAGuc	CUGGAGUCCAACAAGGAAG	-2.1	-2.1	-2.1	1	1	2	-38.9	61.5	-4.6	2	II	52.6	48.3	66.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1018	NM_016406	Huesken	Ufc1	51506	UGGACUCCAGUCGGAACCAau	UGGUUCCGACUGGAGUCCA	-2.1	-2.1	-2.8	-1	0	3	-43.2	44.5	-6.1	2	II	57.9	48.9	71.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1019	NM_016406	Huesken	Ufc1	51506	UCGGAACCAAUCGUUGUCAgc	UGACAACGAUUGGUUCCGA	-2.1	-2.4	0.1	0	0	3	-37.7	55.5	-1.1	6	II	47.4	52.2	76.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1020	NM_016406	Huesken	Ufc1	51506	GGAACCAAUCGUUGUCAGCau	GCUGACAACGAUUGGUUCC	-3.4	-3.3	0.1	-1	1	2	-38.4	60.1	10.4	3	II	52.6	43.6	78	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1021	NM_016406	Huesken	Ufc1	51506	CGUUGUCAGCAUUCUUGUUgu	AACAAGAAUGCUGACAACG	-0.9	-2.4	1.7	0	-2	2	-34.5	69.2	-0.7	2	III	42.1	34.2	43.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1022	NM_016406	Huesken	Ufc1	51506	UUGUCAGCAUUCUUGUUGUuc	ACAACAAGAAUGCUGACAA	-2.2	-0.9	1.7	0	2	2	-34.2	84.9	-4	7	II	36.8	63.1	86.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1023	NM_016406	Huesken	Ufc1	51506	CAUUCUUGUUGUUCUCCACau	GUGGAGAACAACAAGAAUG	-2.2	-2.1	0.3	0	1	2	-34.4	86	8.4	4	II	42.1	52.4	68.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1024	NM_016406	Huesken	Ufc1	51506	GUUGUUCUCCACAUACCGGau	CCGGUAUGUGGAGAACAAC	-3.3	-2.2	-0.7	1	4	4	-38.5	63.3	-0.3	3	II	52.6	52.9	72.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1025	NM_016406	Huesken	Ufc1	51506	UCUCCACAUACCGGAUAAGgg	CUUAUCCGGUAUGUGGAGA	-2.1	-2.4	-2.4	0	2	4	-38	52.4	-4.7	4	II	47.4	48.3	78.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1026	NM_016406	Huesken	Ufc1	51506	ACAUACCGGAUAAGGGACUga	AGUCCCUUAUCCGGUAUGU	-2.1	-2.2	-0.2	1	1	4	-39	47	-3.9	6	II	47.4	48.4	74.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1027	NM_016406	Huesken	Ufc1	51506	CAUACCGGAUAAGGGACUGau	CAGUCCCUUAUCCGGUAUG	-2.1	-2.1	-0.2	-2	1	4	-38.9	50.4	0.3	4	II	52.6	43.9	78.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1028	NM_016406	Huesken	Ufc1	51506	AUACCGGAUAAGGGACUGAua	UCAGUCCCUUAUCCGGUAU	-2.4	-1.1	-0.2	1	1	4	-39.2	48.2	-1.5	7	II	47.4	49.7	88.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1029	NM_016406	Huesken	Ufc1	51506	UACCGGAUAAGGGACUGAUau	AUCAGUCCCUUAUCCGGUA	-1.1	-1.3	-0.2	1	1	4	-39.2	58.3	-4	6	II	47.4	55.5	99.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1030	NM_016406	Huesken	Ufc1	51506	CUGAUAUUCCUCCUUCAGUcg	ACUGAAGGAGGAAUAUCAG	-2.2	-2.1	-0.9	1	-1	2	-36.3	72.8	-3.6	4	II	42.1	52	75.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1031	NM_016406	Huesken	Ufc1	51506	AUAUUCCUCCUUCAGUCGCug	GCGACUGAAGGAGGAAUAU	-3.4	-1.1	0.9	2	5	3	-37.9	76	12.8	6	Ia	47.4	66.3	106.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1032	NM_016406	Huesken	Ufc1	51506	UAUUCCUCCUUCAGUCGCUgc	AGCGACUGAAGGAGGAAUA	-2.1	-1.3	0.9	1	3	3	-38.9	72.5	-8.9	7	II	47.4	63.9	93.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1033	NM_016406	Huesken	Ufc1	51506	AUUCCUCCUUCAGUCGCUGca	CAGCGACUGAAGGAGGAAU	-2.1	-1.1	0.4	2	5	3	-39.7	59.7	0	4	Ib	52.6	57	100.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1034	NM_016406	Huesken	Ufc1	51506	UCCUUCAGUCGCUGCACCCac	GGGUGCAGCGACUGAAGGA	-3.3	-2.4	-0.2	-1	3	3	-44.2	59.4	5.1	5	Ib	63.2	62.9	85.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1035	NM_016406	Huesken	Ufc1	51506	AGUCGCUGCACCCACAACUca	AGUUGUGGGUGCAGCGACU	-2.1	-2.1	-4.7	4	1	3	-42.6	53.7	-6.3	3	II	57.9	55.3	80.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1036	NM_016406	Huesken	Ufc1	51506	UCACGAUCUCGGGGUCCGGcg	CCGGACCCCGAGAUCGUGA	-3.3	-2.4	-1.4	1	4	5	-45.4	35	0	3	Ib	68.4	53.9	56.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1037	NM_014176	Huesken	HSPC150	29089	UUUCUUUUCUAUGCCUACUag	AGUAGGCAUAGAAAAGAAA	-2.1	-0.9	2.7	3	2	3	-32.4	96.4	1.4	7	II	31.6	73.6	101.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1038	NM_014176	Huesken	HSPC150	29089	CUUUUCUAUGCCUACUAGCug	GCUAGUAGGCAUAGAAAAG	-3.4	-2.1	-2.1	0	1	3	-35	80.2	0.7	4	II	42.1	62	106	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1039	NM_014176	Huesken	HSPC150	29089	UACUAGCUGACUGGCCUUCcu	GAAGGCCAGUCAGCUAGUA	-2.4	-1.3	-1.6	0	2	4	-40.8	63	10.8	7	Ib	52.6	62.4	91.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1040	NM_014176	Huesken	HSPC150	29089	CCUUCCUUUUCUGUGUUGAgu	UCAACACAGAAAAGGAAGG	-2.4	-3.3	1.2	0	-2	2	-35.3	75.7	-2.8	4	III	42.1	36.1	65.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1041	NM_014176	Huesken	HSPC150	29089	UGUUGAGUUGUGUACUCUGga	CAGAGUACACAACUCAACA	-2.1	-2.1	-3.5	0	3	1	-35.7	70.7	0	5	Ib	42.1	65.5	83	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1042	NM_014176	Huesken	HSPC150	29089	UUGUGUACUCUGGAGUCACca	GUGACUCCAGAGUACACAA	-2.2	-0.9	-0.5	0	3	2	-38.4	66.4	7.4	6	Ia	47.4	69.3	108	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1043	NM_014176	Huesken	HSPC150	29089	GUGUACUCUGGAGUCACCAgc	UGGUGACUCCAGAGUACAC	-2.1	-2.2	-1.6	1	0	2	-40.8	55.9	1.3	3	II	52.6	45.1	80.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1044	NM_014176	Huesken	HSPC150	29089	GUCACCAGCCUCUGGUAGAuu	UCUACCAGAGGCUGGUGAC	-2.4	-2.2	-5.4	0	-2	3	-43.1	49.1	-6.1	1	III	57.9	33.6	63.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1045	NM_014176	Huesken	HSPC150	29089	UCACCAGCCUCUGGUAGAUua	AUCUACCAGAGGCUGGUGA	-1.1	-2.4	-5.4	1	1	3	-42	46.3	-3.3	4	II	52.6	41.7	97	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1046	NM_014176	Huesken	HSPC150	29089	CUCUGGUAGAUUAUCAAGCau	GCUUGAUAAUCUACCAGAG	-3.4	-2.1	0.9	1	1	2	-35.3	73	8.2	4	II	42.1	63.1	101	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1047	NM_014176	Huesken	HSPC150	29089	AGAUUAUCAAGCAUCUCUUcc	AAGAGAUGCUUGAUAAUCU	-0.9	-2.1	-1.3	2	2	2	-32.9	82.6	-6.6	6	II	31.6	58.8	99.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1048	NM_014176	Huesken	HSPC150	29089	GAUUAUCAAGCAUCUCUUCcu	GAAGAGAUGCUUGAUAAUC	-2.4	-2.4	0.5	0	1	2	-33.2	76.1	7.8	5	II	36.8	50.6	85.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1049	NM_014176	Huesken	HSPC150	29089	UUAUCAAGCAUCUCUUCCUca	AGGAAGAGAUGCUUGAUAA	-2.1	-0.9	0.7	1	3	2	-35.1	85.3	-6.3	8	II	36.8	74.5	113	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1050	NM_014176	Huesken	HSPC150	29089	AUCAAGCAUCUCUUCCUCAuc	UGAGGAAGAGAUGCUUGAU	-2.1	-1.1	0.7	1	1	2	-37.4	67.3	-1.1	6	II	42.1	55.9	91.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1051	NM_014176	Huesken	HSPC150	29089	CAAGCAUCUCUUCCUCAUCag	GAUGAGGAAGAGAUGCUUG	-2.4	-2.1	0.7	0	0	2	-37.4	65.4	10.8	3	II	47.4	54.8	95.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1052	NM_014176	Huesken	HSPC150	29089	GCAUCUCUUCCUCAUCAGCcu	GCUGAUGAGGAAGAGAUGC	-3.4	-3.4	0.8	0	1	2	-39.9	62	10.5	2	II	52.6	43.6	73.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1053	NM_014176	Huesken	HSPC150	29089	UUUCUGUCUUGCAUGCUUCuc	GAAGCAUGCAAGACAGAAA	-2.4	-0.9	1.8	2	4	2	-35.6	84.1	4.8	8	Ia	42.1	75.9	97.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1054	NM_014176	Huesken	HSPC150	29089	CUGUCCACUGUCUGGCAUUcu	AAUGCCAGACAGUGGACAG	-0.9	-2.1	-1.3	-2	-3	3	-40.2	55.7	-8.3	2	III	52.6	42.6	77.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1055	NM_014176	Huesken	HSPC150	29089	GUCCACUGUCUGGCAUUCUug	AGAAUGCCAGACAGUGGAC	-2.1	-2.2	-1.3	2	-1	3	-40.5	49.8	-1.3	3	III	52.6	41.1	95	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1056	NM_014176	Huesken	HSPC150	29089	UCUGGCAUUCUUGAGGAAGgc	CUUCCUCAAGAAUGCCAGA	-2.1	-2.4	1.1	0	2	3	-38.1	60.9	3	5	II	47.4	59.7	76	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1057	NM_014176	Huesken	HSPC150	29089	AUUAUAUUUAAAUUCUGAGga	CUCAGAAUUUAAAUAUAAU	-2.1	-1.1	2.8	2	5	1	-24.8	108.8	4.6	8	Ia	15.8	73.1	85.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1058	NM_014176	Huesken	HSPC150	29089	UUAAAUUCUGAGGAUAUGUca	ACAUAUCCUCAGAAUUUAA	-2.2	-0.9	1.6	1	2	2	-30.6	89.1	1	9	II	26.3	76.3	114	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1059	NM_014176	Huesken	HSPC150	29089	AGCCAUGAGCGGGUCAUCAgg	UGAUGACCCGCUCAUGGCU	-2.1	-2.1	-1.1	3	0	5	-43.3	45.5	1.3	3	II	57.9	43.4	75.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1060	NM_014176	Huesken	HSPC150	29089	CCAUGAGCGGGUCAUCAGGgu	CCUGAUGACCCGCUCAUGG	-3.3	-3.3	-0.8	0	0	5	-43.2	40.9	3.4	2	II	63.2	41.7	83.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1061	NM_014176	Huesken	HSPC150	29089	CAUGAGCGGGUCAUCAGGGuu	CCCUGAUGACCCGCUCAUG	-3.3	-2.1	-0.8	0	3	5	-43.2	38.6	-1.9	2	II	63.2	50.2	91.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1062	NM_014176	Huesken	HSPC150	29089	AUGAGCGGGUCAUCAGGGUug	ACCCUGAUGACCCGCUCAU	-2.2	-1.1	-0.1	2	2	5	-43.3	44.4	-6.3	4	II	57.9	47.7	100.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1063	NM_014176	Huesken	HSPC150	29089	GGGUCAUCAGGGUUGGGUUcu	AACCCAACCCUGAUGACCC	-0.9	-3.3	1.6	1	-1	3	-42.5	55.9	-1.6	1	III	57.9	30.6	52.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1064	NM_014176	Huesken	HSPC150	29089	UGGGUUCUGACAUGAGCAGcu	CUGCUCAUGUCAGAACCCA	-2.1	-2.1	0.1	0	2	3	-40.4	56.2	-2.4	5	II	52.6	54.8	104.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1065	NM_014176	Huesken	HSPC150	29089	GGUUCUGACAUGAGCAGCUga	AGCUGCUCAUGUCAGAACC	-2.1	-3.3	-0.1	0	0	2	-40.5	52.3	-6.6	4	III	52.6	42	79.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1066	NM_014176	Huesken	HSPC150	29089	GCAGCUGAAUAGAGGUCAAca	UUGACCUCUAUUCAGCUGC	-0.9	-3.4	0.6	-1	-2	2	-38.4	41.6	-4	2	III	47.4	23.4	49.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1067	NM_014176	Huesken	HSPC150	29089	UAGAGGUCAACACAGUUGCga	GCAACUGUGUUGACCUCUA	-3.4	-1.3	-0.8	1	3	2	-38.1	72.7	7.5	8	Ib	47.4	75.9	114.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1068	NM_014176	Huesken	HSPC150	29089	GGUCAACACAGUUGCGAUGuu	CAUCGCAACUGUGUUGACC	-2.1	-3.3	-0.8	1	0	3	-38.2	51.4	5.7	3	II	52.6	35.5	84.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1069	NM_014176	Huesken	HSPC150	29089	AACACAGUUGCGAUGUUGAgg	UCAACAUCGCAACUGUGUU	-2.4	-0.9	-0.8	1	1	3	-35.8	68.5	-6.4	6	II	42.1	50.5	102.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1070	NM_014176	Huesken	HSPC150	29089	ACAGUUGCGAUGUUGAGGGau	CCCUCAACAUCGCAACUGU	-3.3	-2.2	1.5	2	5	3	-39.3	62.1	2.3	6	Ib	52.6	63.6	106.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1071	NM_014176	Huesken	HSPC150	29089	GGGAUGGUCUCCAAGCACCuu	GGUGCUUGGAGACCAUCCC	-3.3	-3.3	-2.3	1	0	3	-44	43.6	0.1	1	II	63.2	48.1	80.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1072	NM_014176	Huesken	HSPC150	29089	GGAUGGUCUCCAAGCACCUuu	AGGUGCUUGGAGACCAUCC	-2.1	-3.3	-2.5	0	0	2	-42.8	37.7	-8.9	1	III	57.9	40.2	65.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1073	NM_014176	Huesken	HSPC150	29089	GAUGGUCUCCAAGCACCUUuu	AAGGUGCUUGGAGACCAUC	-0.9	-2.4	-2.5	1	0	2	-40.4	46.5	-1.7	1	III	52.6	37.3	60.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1074	NM_014176	Huesken	HSPC150	29089	GUCUCCAAGCACCUUUUGGug	CCAAAAGGUGCUUGGAGAC	-3.3	-2.2	-2	1	2	2	-38.7	70.3	4.7	3	II	52.6	47.1	84.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1075	NM_014176	Huesken	HSPC150	29089	AGCACCUUUUGGUGGCAAUuu	AUUGCCACCAAAAGGUGCU	-1.1	-2.1	-4.2	1	-1	3	-38.4	65.8	-4	3	II	47.4	38.5	43.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1076	NM_014176	Huesken	HSPC150	29089	CUUUUGGUGGCAAUUUGAGaa	CUCAAAUUGCCACCAAAAG	-2.1	-2.1	1.3	0	2	3	-33.7	68.2	-4.6	5	II	42.1	51	68.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1077	NM_014176	Huesken	HSPC150	29089	UGGUGGCAAUUUGAGAACAuc	UGUUCUCAAAUUGCCACCA	-2.1	-2.1	1.7	0	-1	3	-36.5	57.3	-0.7	4	II	42.1	51	53.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1078	NM_014176	Huesken	HSPC150	29089	GGCAAUUUGAGAACAUCCAga	UGGAUGUUCUCAAAUUGCC	-2.1	-3.3	1	2	-2	3	-35.7	61.8	-3.6	4	II	42.1	41.7	71.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1079	NM_014176	Huesken	HSPC150	29089	CAAUUUGAGAACAUCCAGAca	UCUGGAUGUUCUCAAAUUG	-2.4	-2.1	0.9	0	-1	2	-33.5	72.4	-6.1	6	II	36.8	53.5	80.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1080	NM_014176	Huesken	HSPC150	29089	GAGAACAUCCAGACAAAUCcu	GAUUUGUCUGGAUGUUCUC	-2.4	-2.4	1.4	1	0	2	-35.1	66.5	9.8	4	II	42.1	53.9	75	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1081	NM_014176	Huesken	HSPC150	29089	AACAUCCAGACAAAUCCUUcc	AAGGAUUUGUCUGGAUGUU	-0.9	-0.9	0	2	1	2	-34.5	65.6	-8.9	6	II	36.8	54.9	79.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1082	NM_014176	Huesken	HSPC150	29089	CAUCCAGACAAAUCCUUCCag	GGAAGGAUUUGUCUGGAUG	-3.3	-2.1	0	1	1	2	-37.1	71.1	7.7	5	II	47.4	59.6	96.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1083	NM_014176	Huesken	HSPC150	29089	GACAAAUCCUUCCAGCAGAau	UCUGCUGGAAGGAUUUGUC	-2.4	-2.4	0.1	2	-2	2	-38.2	53.6	-1	4	II	47.4	38.8	87.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1084	NM_014176	Huesken	HSPC150	29089	AAUCCUUCCAGCAGAAUCAau	UGAUUCUGCUGGAAGGAUU	-2.1	-0.9	-3	3	1	2	-37.1	72.3	-8.7	6	II	42.1	59.1	95.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1085	NM_014176	Huesken	HSPC150	29089	AAUCAAUGUUUGGAUGAUAaa	UAUCAUCCAAACAUUGAUU	-1.3	-0.9	-0.1	3	0	2	-30.4	66.2	-1.1	6	II	26.3	50.3	67.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1086	NM_014176	Huesken	HSPC150	29089	UGUUUGGAUGAUAAAUUGGag	CCAAUUUAUCAUCCAAACA	-3.3	-2.1	3.5	0	3	2	-31.1	84.4	2.7	8	Ib	31.6	70.8	101.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1087	NM_014176	Huesken	HSPC150	29089	UUUGGAUGAUAAAUUGGAGug	CUCCAAUUUAUCAUCCAAA	-2.1	-0.9	4	1	5	2	-31.3	78.6	2	6	Ia	31.6	66.5	107.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1088	NM_014176	Huesken	HSPC150	29089	GGAUGAUAAAUUGGAGUGAga	UCACUCCAAUUUAUCAUCC	-2.4	-3.3	4.5	0	-2	2	-34.1	55.1	-0.7	5	II	36.8	33.8	56.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1089	NM_014176	Huesken	HSPC150	29089	AAAUUGGAGUGAGAAAUCGga	CGAUUUCUCACUCCAAUUU	-2.4	-0.9	0.9	2	4	2	-32.6	66.2	0	8	Ia	36.8	67.2	106.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1090	NM_014176	Huesken	HSPC150	29089	AUUGGAGUGAGAAAUCGGAuc	UCCGAUUUCUCACUCCAAU	-2.4	-1.1	0.9	2	2	3	-36.5	54.2	-6.3	6	II	42.1	53.4	109.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1091	NM_014176	Huesken	HSPC150	29089	AAAUCGGAUCUGAGGAGGUuc	ACCUCCUCAGAUCCGAUUU	-2.2	-0.9	1.3	0	3	3	-38.9	51.4	-6.6	6	II	47.4	53.3	100.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1092	NM_014176	Huesken	HSPC150	29089	UCGGAUCUGAGGAGGUUCAaa	UGAACCUCCUCAGAUCCGA	-2.1	-2.4	0.1	0	-1	3	-41.4	52.7	-3.6	6	II	52.6	49.9	105.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1093	NM_014176	Huesken	HSPC150	29089	CGGAUCUGAGGAGGUUCAAau	UUGAACCUCCUCAGAUCCG	-0.9	-2.4	-0.5	-1	-4	3	-39.9	43.3	-5.8	3	III	52.6	25.2	56.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1094	NM_014176	Huesken	HSPC150	29089	GAGGUUCAAAUGGGUACCUcu	AGGUACCCAUUUGAACCUC	-2.1	-2.4	-1.2	-1	0	3	-38.1	49.8	-4	2	III	47.4	42.5	63.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1095	NM_014176	Huesken	HSPC150	29089	UUCAAAUGGGUACCUCUCAgg	UGAGAGGUACCCAUUUGAA	-2.1	-0.9	0.5	2	0	3	-37.1	67.2	1.4	8	II	42.1	63.2	87.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1096	NM_014176	Huesken	HSPC150	29089	CAAAUGGGUACCUCUCAGGaa	CCUGAGAGGUACCCAUUUG	-3.3	-2.1	-0.7	-1	1	3	-39.2	60.6	-6.7	6	II	52.6	58.3	78.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1097	NM_014176	Huesken	HSPC150	29089	AUGGGUACCUCUCAGGAAUga	AUUCCUGAGAGGUACCCAU	-1.1	-1.1	-0.7	2	0	3	-39.7	60.1	-0.9	4	II	47.4	51.3	114.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1098	NM_014176	Huesken	HSPC150	29089	ACCUCUCAGGAAUGAUAACuu	GUUAUCAUUCCUGAGAGGU	-2.2	-2.2	-0.7	1	1	2	-36.4	63.9	9.7	3	II	42.1	43.9	75.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1099	NM_014176	Huesken	HSPC150	29089	CUCUCAGGAAUGAUAACUUcu	AAGUUAUCAUUCCUGAGAG	-0.9	-2.1	0.2	-1	-1	2	-33.9	65.5	-6.2	4	III	36.8	46.6	79.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1100	NM_014176	Huesken	HSPC150	29089	AUGAUAACUUCUAGCUUAAaa	UUAAGCUAGAAGUUAUCAU	-0.9	-1.1	0.3	0	-1	2	-30.6	75.6	-5.7	7	II	26.3	49.3	89.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1101	NM_014176	Huesken	HSPC150	29089	AAAACACCUUUCUCAUAAGgu	CUUAUGAGAAAGGUGUUUU	-2.1	-0.9	0.6	1	3	2	-30.8	76.8	-2.4	5	Ia	31.6	56.9	92.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1102	NM_014176	Huesken	HSPC150	29089	CCUUUCUCAUAAGGUGUGUug	ACACACCUUAUGAGAAAGG	-2.2	-3.3	-1.9	-1	-2	2	-35.7	63.8	-3.7	4	II	42.1	35.9	74.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1103	NM_014176	Huesken	HSPC150	29089	GUGUUGGCUCCACCUAAUAuu	UAUUAGGUGGAGCCAACAC	-1.3	-2.2	-1.8	0	-3	3	-38.3	54.2	-3.7	3	III	47.4	37.3	57.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1104	NM_014176	Huesken	HSPC150	29089	CUCCACCUAAUAUUUGAGCuc	GCUCAAAUAUUAGGUGGAG	-3.4	-2.1	0.6	0	1	2	-35	71.3	10.4	3	II	42.1	53.7	87.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1105	NM_014176	Huesken	HSPC150	29089	CACCUAAUAUUUGAGCUCGca	CGAGCUCAAAUAUUAGGUG	-2.4	-2.1	1.1	0	0	2	-34.1	65.2	1	4	II	42.1	54.3	90	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1106	NM_014176	Huesken	HSPC150	29089	ACCUAAUAUUUGAGCUCGCag	GCGAGCUCAAAUAUUAGGU	-3.4	-2.2	1.8	1	3	3	-35.4	58.2	7.5	5	Ia	42.1	54	71.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1107	NM_014176	Huesken	HSPC150	29089	UAAUAUUUGAGCUCGCAGGuc	CCUGCGAGCUCAAAUAUUA	-3.3	-1.3	2.4	2	4	3	-35.3	89.1	0.4	9	Ia	42.1	79.9	102.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1108	NM_014176	Huesken	HSPC150	29089	AUAUUUGAGCUCGCAGGUCau	GACCUGCGAGCUCAAAUAU	-2.4	-1.1	2.1	2	4	3	-37.7	60.4	5.1	7	Ia	47.4	64.1	100.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1109	NM_014176	Huesken	HSPC150	29089	UCGCAGGUCAUCCAUUUGGuc	CCAAAUGGAUGACCUGCGA	-3.3	-2.4	-0.6	2	2	3	-39.6	59.4	2.8	7	II	52.6	66.1	95.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1110	NM_014176	Huesken	HSPC150	29089	GUCAUCCAUUUGGUCUUUAuc	UAAAGACCAAAUGGAUGAC	-1.3	-2.2	-1.1	0	-2	2	-33.7	66.3	-1.4	3	III	36.8	35.4	63.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1111	NM_014176	Huesken	HSPC150	29089	GGUCUUUAUCUUGCCAACAug	UGUUGGCAAGAUAAAGACC	-2.1	-3.3	0.8	2	-2	3	-35.7	63.5	-0.7	3	II	42.1	42.6	75.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1112	NM_014176	Huesken	HSPC150	29089	CUUGCCAACAUGUGAUGCCug	GGCAUCACAUGUUGGCAAG	-3.3	-2.1	-0.2	-1	2	3	-38.9	60.3	5.4	4	II	52.6	56.8	87.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1113	NM_014176	Huesken	HSPC150	29089	UGCCAACAUGUGAUGCCUGgg	CAGGCAUCACAUGUUGGCA	-2.1	-2.1	-0.5	1	3	3	-40.1	50.1	2.4	4	II	52.6	56.7	90.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1114	NM_001001481	Huesken	FLJ11011	55284	ACCAUUUUGUUUUCUUUGGau	CCAAAGAAAACAAAAUGGU	-3.3	-2.2	0.4	3	2	2	-30.1	94	3	6	Ia	31.6	62.7	101.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1115	NM_001001481	Huesken	FLJ11011	55284	UUUGUUUUCUUUGGAUUCUug	AGAAUCCAAAGAAAACAAA	-2.1	-0.9	1.6	1	2	2	-29.4	92.1	-1	8	II	26.3	71.4	105.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1116	NM_001001481	Huesken	FLJ11011	55284	UUUCUUUGGAUUCUUGUUAca	UAACAAGAAUCCAAAGAAA	-1.3	-0.9	1.6	3	1	2	-29.8	98.7	4	9	II	26.3	69.6	114.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1117	NM_001001481	Huesken	FLJ11011	55284	UUCUUGUUACAUGUUCGCAca	UGCGAACAUGUAACAAGAA	-2.1	-0.9	0.5	1	2	3	-33.7	87.8	3.9	7	II	36.8	64.3	103.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1118	NM_001001481	Huesken	FLJ11011	55284	UCUUGUUACAUGUUCGCACau	GUGCGAACAUGUAACAAGA	-2.2	-2.4	0.3	2	4	3	-35	85.3	9.7	7	Ia	42.1	71.5	125.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1119	NM_001001481	Huesken	FLJ11011	55284	UUGUUACAUGUUCGCACAUaa	AUGUGCGAACAUGUAACAA	-1.1	-0.9	-1.4	-1	1	3	-33.7	70.6	1.5	5	II	36.8	56.1	88.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1120	NM_001001481	Huesken	FLJ11011	55284	AAAAGAAUUAUCCGGUGGUcg	ACCACCGGAUAAUUCUUUU	-2.2	-0.9	0.1	0	3	4	-33.7	65.6	-3.9	7	II	36.8	58.8	96.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1121	NM_001001481	Huesken	FLJ11011	55284	AAAGAAUUAUCCGGUGGUCgu	GACCACCGGAUAAUUCUUU	-2.4	-0.9	0.1	1	4	4	-35.2	57.6	5.4	6	Ia	42.1	56.7	96.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1122	NM_001001481	Huesken	FLJ11011	55284	UAUCCGGUGGUCGUCUCUUuu	AAGAGACGACCACCGGAUA	-0.9	-1.3	-0.1	2	3	4	-40.5	59.1	-4	6	II	52.6	61	82.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1123	NM_001001481	Huesken	FLJ11011	55284	UGGUCGUCUCUUUUCCUUGca	CAAGGAAAAGAGACGACCA	-2.1	-2.1	0.3	1	2	2	-37.1	82.6	5.4	6	II	47.4	68	109.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1124	NM_001001481	Huesken	FLJ11011	55284	GGUCGUCUCUUUUCCUUGCag	GCAAGGAAAAGAGACGACC	-3.4	-3.3	2	2	1	2	-38.4	65.2	10.4	2	II	52.6	44	112.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1125	NM_001001481	Huesken	FLJ11011	55284	UUUCCUUGCAGCUGGAAAGca	CUUUCCAGCUGCAAGGAAA	-2.1	-0.9	-3	2	3	2	-37.4	79.8	-2.4	6	Ia	47.4	68.8	103	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1126	NM_001001481	Huesken	FLJ11011	55284	UCCUUGCAGCUGGAAAGCAug	UGCUUUCCAGCUGCAAGGA	-2.1	-2.4	-1.4	1	0	2	-41.1	44.5	-3.8	4	II	52.6	47.3	110.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1127	NM_001001481	Huesken	FLJ11011	55284	AGCUGGAAAGCAUGCUAAUaa	AUUAGCAUGCUUUCCAGCU	-1.1	-2.1	-1.2	0	-1	2	-36.8	54	-6.3	3	II	42.1	39.8	67.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1128	NM_001001481	Huesken	FLJ11011	55284	GGAAAGCAUGCUAAUAAUGcu	CAUUAUUAGCAUGCUUUCC	-2.1	-3.3	1.3	0	0	2	-32.5	58.5	0.8	3	II	36.8	46.6	93.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1129	NM_001001481	Huesken	FLJ11011	55284	AAAGCAUGCUAAUAAUGCUaa	AGCAUUAUUAGCAUGCUUU	-2.1	-0.9	-2.5	3	3	2	-32.3	73.8	-1.7	4	II	31.6	60.5	84.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1130	NM_001001481	Huesken	FLJ11011	55284	AAUGCUAAGACAAACUGAUug	AUCAGUUUGUCUUAGCAUU	-1.1	-0.9	-0.4	2	2	2	-32.3	71.1	-8.9	6	II	31.6	58.9	107	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1131	NM_001001481	Huesken	FLJ11011	55284	AUGCUAAGACAAACUGAUUgg	AAUCAGUUUGUCUUAGCAU	-0.9	-1.1	-0.4	2	0	2	-32.3	67.5	-4.3	5	II	31.6	55	104.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1132	NM_001001481	Huesken	FLJ11011	55284	CUAAGACAAACUGAUUGGAcu	UCCAAUCAGUUUGUCUUAG	-2.4	-2.1	0.6	-1	-1	2	-33.5	57.9	-5.1	4	II	36.8	41	85	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1133	NM_001001481	Huesken	FLJ11011	55284	AGACAAACUGAUUGGACUGag	CAGUCCAAUCAGUUUGUCU	-2.1	-2.1	0.6	1	3	2	-35.6	61.9	8	5	Ia	42.1	56.4	121.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1134	NM_001001481	Huesken	FLJ11011	55284	CUGAUUGGACUGAGAGCGCug	GCGCUCUCAGUCCAAUCAG	-3.4	-2.1	1.5	-2	1	4	-41	44.4	2.8	3	II	57.9	51.4	108.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1135	NM_001001481	Huesken	FLJ11011	55284	GAGAGCGCUGGGGACCAGUcu	ACUGGUCCCCAGCGCUCUC	-2.2	-2.4	-2.7	0	-1	4	-46.6	31.7	-4	1	III	68.4	37.4	93.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1136	NM_001001481	Huesken	FLJ11011	55284	GCGCUGGGGACCAGUCUUCug	GAAGACUGGUCCCCAGCGC	-2.4	-3.4	-2.7	1	-1	4	-45.4	28.4	0.1	2	II	68.4	36.9	80.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1137	NM_001001481	Huesken	FLJ11011	55284	CGCUGGGGACCAGUCUUCUgu	AGAAGACUGGUCCCCAGCG	-2.1	-2.4	-2.7	-1	-2	4	-44.1	37.8	-6	1	III	63.2	34.2	88.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1138	NM_001001481	Huesken	FLJ11011	55284	GGGGACCAGUCUUCUGUUAga	UAACAGAAGACUGGUCCCC	-1.3	-3.3	-1.5	1	-4	4	-40.6	46.7	-0.4	1	III	52.6	22.1	64.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1139	NM_001001481	Huesken	FLJ11011	55284	GGACCAGUCUUCUGUUAGAau	UCUAACAGAAGACUGGUCC	-2.4	-3.3	-1.5	1	-2	2	-38.5	47.8	-6.1	1	III	47.4	27.4	73.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1140	NM_001001481	Huesken	FLJ11011	55284	AGUCUUCUGUUAGAAUGGAua	UCCAUUCUAACAGAAGACU	-2.4	-2.1	0	3	1	2	-35	56.7	-3.8	4	II	36.8	42.4	64.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1141	NM_001001481	Huesken	FLJ11011	55284	UCUUCUGUUAGAAUGGAUAaa	UAUCCAUUCUAACAGAAGA	-1.3	-2.4	0	0	0	2	-33.1	85.1	-4	7	II	31.6	59.3	83.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1142	NM_001001481	Huesken	FLJ11011	55284	CUGUUAGAAUGGAUAAACAga	UGUUUAUCCAUUCUAACAG	-2.1	-2.1	0.2	-1	-2	2	-31.4	68.8	-6	4	II	31.6	45.1	66.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1143	NM_001001481	Huesken	FLJ11011	55284	UUAGAAUGGAUAAACAGAUau	AUCUGUUUAUCCAUUCUAA	-1.1	-0.9	2.1	2	2	2	-30.6	70.3	-3.9	8	II	26.3	70.4	96.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1144	NM_001001481	Huesken	FLJ11011	55284	UAGAAUGGAUAAACAGAUAug	UAUCUGUUUAUCCAUUCUA	-1.3	-1.3	2.1	0	-1	2	-31	73.5	-1.3	7	II	26.3	59.8	85.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1145	NM_001001481	Huesken	FLJ11011	55284	UGACCAUUGCUAUAAACAUga	AUGUUUAUAGCAAUGGUCA	-1.1	-2.1	-0.2	3	1	2	-32.6	70.8	-4	5	II	31.6	58.1	96.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1146	NM_001001481	Huesken	FLJ11011	55284	UUGCUAUAAACAUGAGGAUga	AUCCUCAUGUUUAUAGCAA	-1.1	-0.9	-0.2	1	1	2	-32.8	71.7	-6.3	7	II	31.6	57.7	104.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1147	NM_001001481	Huesken	FLJ11011	55284	GCUAUAAACAUGAGGAUGAac	UCAUCCUCAUGUUUAUAGC	-2.4	-3.4	1.6	0	-2	2	-34.3	59	-6.3	6	II	36.8	39.5	78.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1148	NM_001001481	Huesken	FLJ11011	55284	UAUAAACAUGAGGAUGAACag	GUUCAUCCUCAUGUUUAUA	-2.2	-1.3	1.6	0	3	2	-31.9	75.3	12.4	7	Ia	31.6	64.9	105.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1149	NM_001001481	Huesken	FLJ11011	55284	UAAACAUGAGGAUGAACAGga	CUGUUCAUCCUCAUGUUUA	-2.1	-1.3	1.6	0	4	2	-33.7	73.7	0	7	Ia	36.8	66	112.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1150	NM_001001481	Huesken	FLJ11011	55284	AACAUGAGGAUGAACAGGAau	UCCUGUUCAUCCUCAUGUU	-2.4	-0.9	1.6	2	1	2	-37.2	58.5	-6.3	7	II	42.1	58.7	108.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1151	NM_001001481	Huesken	FLJ11011	55284	ACAUGAGGAUGAACAGGAAua	UUCCUGUUCAUCCUCAUGU	-0.9	-2.2	1.6	1	0	2	-37.2	44.2	-6.3	5	II	42.1	34.3	73	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1152	NM_001001481	Huesken	FLJ11011	55284	AUGAGGAUGAACAGGAAUAuu	UAUUCCUGUUCAUCCUCAU	-1.3	-1.1	1.8	1	-1	2	-35.3	62.1	-6.4	6	II	36.8	55.3	104	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1153	NM_001001481	Huesken	FLJ11011	55284	GGAUGAACAGGAAUAUUUUca	AAAAUAUUCCUGUUCAUCC	-0.9	-3.3	2.1	0	-1	2	-31.4	64.8	-4.2	4	II	31.6	39.3	53.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1154	NM_001001481	Huesken	FLJ11011	55284	UGAACAGGAAUAUUUUCACca	GUGAAAAUAUUCCUGUUCA	-2.2	-2.1	1.1	0	4	2	-31.3	83.5	9.7	7	Ib	31.6	67.9	82	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1155	NM_001001481	Huesken	FLJ11011	55284	AACAGGAAUAUUUUCACCAgu	UGGUGAAAAUAUUCCUGUU	-2.1	-0.9	0.5	1	2	2	-32.2	80.9	1.6	6	II	31.6	65.8	115.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1156	NM_001001481	Huesken	FLJ11011	55284	ACAGGAAUAUUUUCACCAGua	CUGGUGAAAAUAUUCCUGU	-2.1	-2.2	0.5	1	3	2	-33.4	63.7	3	4	Ib	36.8	53.9	107.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1157	NM_001001481	Huesken	FLJ11011	55284	AGGAAUAUUUUCACCAGUAaa	UACUGGUGAAAAUAUUCCU	-1.3	-2.1	0.5	1	-1	2	-32.6	68	-6	5	II	31.6	53.1	94.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1158	NM_001001481	Huesken	FLJ11011	55284	GAAUAUUUUCACCAGUAAAca	UUUACUGGUGAAAAUAUUC	-0.9	-2.4	0.6	1	-2	2	-29	81.5	1.3	5	II	26.3	43.6	91.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1159	NM_001001481	Huesken	FLJ11011	55284	UUCACCAGUAAACAUGACCug	GGUCAUGUUUACUGGUGAA	-3.3	-0.9	-1.1	0	3	2	-35.8	82	12.1	6	Ib	42.1	78.4	103.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1160	NM_001001481	Huesken	FLJ11011	55284	GACCUGAGGAGAGUCAAAAgg	UUUUGACUCUCCUCAGGUC	-0.9	-2.4	-1	2	-2	2	-38.3	49.8	-1.4	3	III	47.4	35.1	95	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1161	NM_001001481	Huesken	FLJ11011	55284	CUGAGGAGAGUCAAAAGGAua	UCCUUUUGACUCUCCUCAG	-2.4	-2.1	0.2	-1	-2	2	-38.2	41.5	-10.7	3	III	47.4	45.5	78.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1162	NM_001001481	Huesken	FLJ11011	55284	GAGAGUCAAAAGGAUAUCGac	CGAUAUCCUUUUGACUCUC	-2.4	-2.4	1	0	1	2	-34.5	65.7	2.3	4	II	42.1	54.2	85.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1163	NM_001001481	Huesken	FLJ11011	55284	AGAGUCAAAAGGAUAUCGAcu	UCGAUAUCCUUUUGACUCU	-2.4	-2.1	-0.3	1	2	2	-34.5	66.5	-4	6	II	36.8	52.9	74.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1164	NM_001001481	Huesken	FLJ11011	55284	AGUCAAAAGGAUAUCGACUac	AGUCGAUAUCCUUUUGACU	-2.1	-2.1	-4.1	3	2	2	-34.3	67.5	3.8	4	II	36.8	56.1	81.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1165	NM_001001481	Huesken	FLJ11011	55284	CAAAAGGAUAUCGACUACUaa	AGUAGUCGAUAUCCUUUUG	-2.1	-2.1	1.9	-1	-1	2	-33.2	58.7	-5.6	6	II	36.8	57.6	123.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1166	NM_001001481	Huesken	FLJ11011	55284	UAUCGACUACUAAAUUUAAau	UUAAAUUUAGUAGUCGAUA	-0.9	-1.3	2.6	1	0	2	-27.7	76.3	-6.3	6	II	21.1	53.8	79.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1167	NM_001001481	Huesken	FLJ11011	55284	AUCGACUACUAAAUUUAAAua	UUUAAAUUUAGUAGUCGAU	-0.9	-1.1	2.9	3	0	2	-27.3	82.5	1	5	II	21.1	51.3	88	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1168	NM_001001481	Huesken	FLJ11011	55284	GACUACUAAAUUUAAAUAGaa	CUAUUUAAAUUUAGUAGUC	-2.1	-2.4	-0.9	1	0	1	-25.9	92.5	5.7	6	II	21.1	54.7	83.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1169	NM_001001481	Huesken	FLJ11011	55284	CUAAAUUUAAAUAGAAGUUga	AACUUCUAUUUAAAUUUAG	-0.9	-2.1	1	-1	-1	1	-24.2	89.4	-0.5	6	II	15.8	57.8	96.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1170	NM_001001481	Huesken	FLJ11011	55284	UUAAAUAGAAGUUGAAAUUuu	AAUUUCAACUUCUAUUUAA	-0.9	-0.9	4.1	-1	1	1	-25.3	96.5	1.8	9	II	15.8	72.6	97.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1171	NM_001001481	Huesken	FLJ11011	55284	UUCCCCUUCAUAUAAGGUAcc	UACCUUAUAUGAAGGGGAA	-1.3	-0.9	-3.1	3	0	4	-35.3	77.2	-3.8	5	II	36.8	62.4	111.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1172	NM_001001481	Huesken	FLJ11011	55284	AUAUAAGGUACCUGGUGCAcc	UGCACCAGGUACCUUAUAU	-2.1	-1.1	0.7	0	2	2	-37.4	60.7	-5.8	8	II	42.1	53.4	78	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1173	NM_001001481	Huesken	FLJ11011	55284	UAAGGUACCUGGUGCACCUuc	AGGUGCACCAGGUACCUUA	-2.1	-1.3	-6.5	0	3	2	-41.5	60.9	-4	5	II	52.6	66.3	93.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1174	NM_001001481	Huesken	FLJ11011	55284	UACCUGGUGCACCUUCCAUgu	AUGGAAGGUGCACCAGGUA	-1.1	-1.3	-1.5	2	2	2	-41.5	63.3	0.7	5	II	52.6	54.6	86.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1175	NM_001001481	Huesken	FLJ11011	55284	CUGGUGCACCUUCCAUGUCua	GACAUGGAAGGUGCACCAG	-2.4	-2.1	-1.5	0	0	2	-41.4	49.3	10.8	0	II	57.9	47	94.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1176	NM_001001481	Huesken	FLJ11011	55284	GGUGCACCUUCCAUGUCUAca	UAGACAUGGAAGGUGCACC	-1.3	-3.3	0.2	0	-1	2	-40.6	45.7	-8.7	1	III	52.6	24.8	38.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1177	NM_001001481	Huesken	FLJ11011	55284	CAUGUCUACAAUCCACUGUgu	ACAGUGGAUUGUAGACAUG	-2.2	-2.1	0	1	-1	2	-36	77.8	1.8	6	II	42.1	53	110.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1178	NM_001001481	Huesken	FLJ11011	55284	AUGUCUACAAUCCACUGUGua	CACAGUGGAUUGUAGACAU	-2.1	-1.1	-0.1	1	3	2	-36	76.6	0.1	6	Ia	42.1	68.4	115.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1179	NM_001001481	Huesken	FLJ11011	55284	UGUCUACAAUCCACUGUGUaa	ACACAGUGGAUUGUAGACA	-2.2	-2.1	-0.1	1	1	2	-37.1	64.6	-11.3	6	II	42.1	50.9	99.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1180	NM_001001481	Huesken	FLJ11011	55284	UCUACAAUCCACUGUGUAAuu	UUACACAGUGGAUUGUAGA	-0.9	-2.4	-1.1	0	-1	2	-35	76.6	-3.8	6	II	36.8	47.8	92.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1181	NM_001001481	Huesken	FLJ11011	55284	UACAAUCCACUGUGUAAUUga	AAUUACACAGUGGAUUGUA	-0.9	-1.3	-0.1	-1	0	2	-32.5	77.6	-1.3	6	II	31.6	57.8	111.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1182	NM_001001481	Huesken	FLJ11011	55284	CACUGUGUAAUUGAAUUUUga	AAAAUUCAAUUACACAGUG	-0.9	-2.1	2.8	-1	-3	1	-28.4	78.7	-3	5	III	26.3	48.9	76.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1183	NM_001001481	Huesken	FLJ11011	55284	GUGUAAUUGAAUUUUGAACac	GUUCAAAAUUCAAUUACAC	-2.2	-2.2	2.1	2	1	1	-27.5	95.7	17.8	5	II	26.3	55.2	73.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1184	NM_001001481	Huesken	FLJ11011	55284	AUUGAAUUUUGAACACUCUuc	AGAGUGUUCAAAAUUCAAU	-2.1	-1.1	-1.8	2	2	1	-29.7	78.7	-3.9	6	II	26.3	63.7	109.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1185	NM_001001481	Huesken	FLJ11011	55284	UUGAAUUUUGAACACUCUUcu	AAGAGUGUUCAAAAUUCAA	-0.9	-0.9	-1.8	1	1	1	-29.5	89.3	3.4	6	II	26.3	73.7	113.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1186	NM_001001481	Huesken	FLJ11011	55284	AAUUUUGAACACUCUUCUCau	GAGAAGAGUGUUCAAAAUU	-2.4	-0.9	0.2	1	4	1	-31	92.9	7.4	7	Ia	31.6	67.5	115.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1187	NM_001001481	Huesken	FLJ11011	55284	CUCUUCUCAUUUAAGGUCAuu	UGACCUUAAAUGAGAAGAG	-2.1	-2.1	0.3	0	-3	2	-33.7	76.9	-5.3	5	II	36.8	48.8	75	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1188	NM_001001481	Huesken	FLJ11011	55284	UCUUCUCAUUUAAGGUCAUuc	AUGACCUUAAAUGAGAAGA	-1.1	-2.4	0.3	-1	1	2	-32.7	70.6	-6.6	5	II	31.6	48.9	68.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1189	NM_001001481	Huesken	FLJ11011	55284	CUCAUUUAAGGUCAUUCCAgg	UGGAAUGACCUUAAAUGAG	-2.1	-2.1	0	0	-2	2	-33.6	79.1	-0.3	4	II	36.8	50.4	96.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1190	NM_001001481	Huesken	FLJ11011	55284	UUUAAGGUCAUUCCAGGAGgu	CUCCUGGAAUGACCUUAAA	-2.1	-0.9	0	1	4	2	-35.8	77.3	8.1	9	Ia	42.1	71.4	100.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1191	NM_001001481	Huesken	FLJ11011	55284	UUAAGGUCAUUCCAGGAGGug	CCUCCUGGAAUGACCUUAA	-3.3	-0.9	-0.8	1	4	2	-38.2	67.1	0.1	7	Ia	47.4	74.7	99.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1192	NM_016021	Huesken	UBE2J1	51465	AAUAUGUAUUCGUUUGCCAga	UGGCAAACGAAUACAUAUU	-2.1	-0.9	1.5	2	3	3	-31.7	85.3	-3.8	7	II	31.6	61	110	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1193	NM_016021	Huesken	UBE2J1	51465	UGUAUUCGUUUGCCAGAUAua	UAUCUGGCAAACGAAUACA	-1.3	-2.1	1.2	0	-1	3	-34.2	70.5	-1.4	6	II	36.8	50.6	91.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1194	NM_016021	Huesken	UBE2J1	51465	AUUCGUUUGCCAGAUAUAUuc	AUAUAUCUGGCAAACGAAU	-1.1	-1.1	1.2	4	1	3	-32.1	73	-6.3	6	II	31.6	56.1	95.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1195	NM_016021	Huesken	UBE2J1	51465	AUUCGUCGGAAUAUAAGAGcu	CUCUUAUAUUCCGACGAAU	-2.1	-1.1	0.6	3	5	3	-32.7	74.9	5.1	5	Ib	36.8	60.5	98.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1196	NM_016021	Huesken	UBE2J1	51465	CUGCCAAUGCCAAAGUCAGga	CUGACUUUGGCAUUGGCAG	-2.1	-2.1	-0.9	1	0	3	-38.6	46.8	-6.9	2	II	52.6	45.7	76.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1197	NM_016021	Huesken	UBE2J1	51465	GGAUGACAAUCAGUACAGCug	GCUGUACUGAUUGUCAUCC	-3.4	-3.3	1.2	0	2	2	-37.5	45.8	7.4	2	II	47.4	37.5	62.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1198	NM_016021	Huesken	UBE2J1	51465	CAGUACAGCUGACCCACCAug	UGGUGGGUCAGCUGUACUG	-2.1	-2.1	-0.4	0	-2	3	-42.6	48.8	-0.7	3	II	57.9	42.4	83.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1199	NM_016021	Huesken	UBE2J1	51465	GGUUGUCUCUUGGCUGGUGgc	CACCAGCCAAGAGACAACC	-2.1	-3.3		1	1	3	-41.2	49	0	1	II	57.9	35	55.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1200	NM_016021	Huesken	UBE2J1	51465	UUGGCUGGUGGCCCUGGAUua	AUCCAGGGCCACCAGCCAA	-1.1	-0.9	-3.8	0	1	5	-45.8	51.8	-3.9	3	II	63.2	52.6	76	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1201	NM_016021	Huesken	UBE2J1	51465	ACAUCUGGUGAAGUAGACAac	UGUCUACUUCACCAGAUGU	-2.1	-2.2	-1	1	1	2	-37.3	60	0.9	4	II	42.1	50	73.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1202	NM_016021	Huesken	UBE2J1	51465	GAAGUAGACAACCUUCUCUga	AGAGAAGGUUGUCUACUUC	-2.1	-2.4	-2.4	1	1	2	-36.1	68.7	0.7	5	II	42.1	52.1	78.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1203	NM_016021	Huesken	UBE2J1	51465	ACUCUGCUGCUGGGCCCGGcg	CCGGGCCCAGCAGCAGAGU	-3.3	-2.2	-0.7	2	4	8	-48.4	26.1	0	3	II	73.7	44.4	47.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1204	NM_016021	Huesken	UBE2J1	51465	CUGCUGCUGGGCCCGGCGCug	GCGCCGGGCCCAGCAGCAG	-3.4	-2.1	-0.8	1	1	11	-50.9	29.8	5.5	1	II	84.2	43.6	35.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1205	NM_016021	Huesken	UBE2J1	51465	UUCUUAGCUACAGGUUGGGua	CCCAACCUGUAGCUAAGAA	-3.3	-0.9	1	-1	4	3	-38	63.6	-2.4	8	Ia	47.4	63.9	78.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1206	NM_016021	Huesken	UBE2J1	51465	AGGUUGGGUAGGUUGAUGAaa	UCAUCAACCUACCCAACCU	-2.4	-2.1		1	0	3	-39.3	67.9	-1.4	7	II	47.4	49.4	47.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1207	NM_016021	Huesken	UBE2J1	51465	UGGGUAGGUUGAUGAAAGGau	CCUUUCAUCAACCUACCCA	-3.3	-2.1	4.4	-1	2	3	-38	54.1	0	5	II	47.4	56.6	56.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1208	NM_016021	Huesken	UBE2J1	51465	UGGCCGUAGCACCCUGGAAug	UUCCAGGGUGCUACGGCCA	-0.9	-2.1	-2.9	3	-1	5	-45.2	45.6	-1.4	2	II	63.2	41	75.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1209	NM_016021	Huesken	UBE2J1	51465	GGUAUAUCAUCUUGUAAAUca	AUUUACAAGAUGAUAUACC	-1.1	-3.3	2.2	0	-2	2	-29.8	79.5	-3.3	4	II	26.3	33.6	47.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1210	NM_016021	Huesken	UBE2J1	51465	UUGUAAAUCAGUUAGUGAAaa	UUCACUAACUGAUUUACAA	-0.9	-0.9	0.6	1	0	1	-30.1	91.1	2	8	II	26.3	61.4	67.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1211	NM_016021	Huesken	UBE2J1	51465	AGUGGUUUAAGUCUGACUCag	GAGUCAGACUUAAACCACU	-2.4	-2.1	0.1	2	4	2	-35.9	83.7	15.2	5	Ib	42.1	65.3	88.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1212	NM_016021	Huesken	UBE2J1	51465	UUCCAGAUGAAUUGACUUCug	GAAGUCAAUUCAUCUGGAA	-2.4	-0.9	-0.5	1	2	2	-33.8	80.2	15.4	8	Ib	36.8	71.6	75.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1213	NM_016021	Huesken	UBE2J1	51465	UCCAGAUGAAUUGACUUCUgc	AGAAGUCAAUUCAUCUGGA	-2.1	-2.4	-0.7	1	0	2	-35	72.8	-1	7	II	36.8	63.2	79.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1214	NM_016021	Huesken	UBE2J1	51465	CCAGAUGAAUUGACUUCUGcc	CAGAAGUCAAUUCAUCUGG	-2.1	-3.3	-1.7	-1	0	2	-34.7	52.1	-1.9	2	II	42.1	47.2	60.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1215	NM_016021	Huesken	UBE2J1	51465	CAGAUGAAUUGACUUCUGCcu	GCAGAAGUCAAUUCAUCUG	-3.4	-2.1	-0.7	-1	1	2	-34.8	71.7	10.1	5	II	42.1	57.5	54.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1216	NM_016021	Huesken	UBE2J1	51465	CUGCCUUAAAGCUUAUUUGcc	CAAAUAAGCUUUAAGGCAG	-2.1	-2.1	-2.4	1	0	3	-31.8	85.3	-2	3	II	36.8	58.1	56	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1217	NM_016021	Huesken	UBE2J1	51465	GUUCUUUGGCUUCUUGGUCag	GACCAAGAAGCCAAAGAAC	-2.4	-2.2		3	3	3	-36.6	72.8	15.2	4	II	47.4	53.3	56.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1218	NM_016021	Huesken	UBE2J1	51465	UCUUUGGCUUCUUGGUCAGcu	CUGACCAAGAAGCCAAAGA	-2.1	-2.4	1	-1	3	3	-37.7	70	0.7	7	Ib	47.4	55	73.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1219	NM_016021	Huesken	UBE2J1	51465	GCUUCCAGAUUUUAAAGGCaa	GCCUUUAAAAUCUGGAAGC	-3.4	-3.4	-0.1	0	2	3	-34.4	69.2	10.4	3	II	42.1	46	50.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1220	NM_016021	Huesken	UBE2J1	51465	UUCCAGAUUUUAAAGGCAAca	UUGCCUUUAAAAUCUGGAA	-0.9	-0.9	-0.1	1	0	3	-31.9	63.9	-3.6	6	II	31.6	58.3	70.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1221	NM_016021	Huesken	UBE2J1	51465	UCCAGAUUUUAAAGGCAACag	GUUGCCUUUAAAAUCUGGA	-2.2	-2.4	-0.1	0	1	3	-33.2	67.4	7.1	5	Ib	36.8	57.6	55.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1222	NM_016021	Huesken	UBE2J1	51465	GCAAGUGCUCUUCUUUCCUca	AGGAAAGAAGAGCACUUGC	-2.1	-3.4	0.2	0	1	2	-37.8	61	3.8	3	III	47.4	44.1	70.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1223	NM_016021	Huesken	UBE2J1	51465	AACCUAUGGCUCCCUCUCCuu	GGAGAGGGAGCCAUAGGUU	-3.3	-0.9	-0.7	4	3	3	-43.1	59	7.5	5	Ia	57.9	62.3	61	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1224	NM_016021	Huesken	UBE2J1	51465	UGGCUCCCUCUCCUUUUGUug	ACAAAAGGAGAGGGAGCCA	-2.2	-2.1	-0.9	1	1	3	-41.3	64.9	-1.6	5	II	52.6	52.3	41.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1225	NM_016021	Huesken	UBE2J1	51465	CCCUCUCCUUUUGUUGGCAua	UGCCAACAAAAGGAGAGGG	-2.1	-3.3	-0.2	-1	-2	3	-39.8	55.7	-0.4	1	III	52.6	30.2	28.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1226	NM_016021	Huesken	UBE2J1	51465	UGAUGGCUAAUAAUGCUGUcc	ACAGCAUUAUUAGCCAUCA	-2.2	-2.1	0	0	2	3	-35	72.3	-4.2	7	II	36.8	63.1	54.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1227	NM_016021	Huesken	UBE2J1	51465	UGGCUAAUAAUGCUGUCCUua	AGGACAGCAUUAUUAGCCA	-2.1	-2.1	0	1	2	3	-37.2	73.4	0.8	6	II	42.1	63.8	74.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1228	NM_016021	Huesken	UBE2J1	51465	UAAUGCUGUCCUUAUACUCca	GAGUAUAAGGACAGCAUUA	-2.4	-1.3	0.7	1	4	2	-34.3	87	8.1	7	Ia	36.8	76.1	91.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1229	NM_016021	Huesken	UBE2J1	51465	AGGAUGAUGGCCUGAGAUGcu	CAUCUCAGGCCAUCAUCCU	-2.1	-2.1	0.2	1	1	4	-40.9	52.6	-4.7	5	Ib	52.6	52.7	64.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1230	NM_016021	Huesken	UBE2J1	51465	AUGAUGGCCUGAGAUGCUCaa	GAGCAUCUCAGGCCAUCAU	-2.4	-1.1	-0.5	2	3	4	-41	55	7.4	6	Ib	52.6	61.4	64.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1231	NM_016021	Huesken	UBE2J1	51465	UGGCCUGAGAUGCUCAAACag	GUUUGAGCAUCUCAGGCCA	-2.2	-2.1	-5.3	2	2	4	-40.4	64	12.1	4	II	52.6	63.5	72.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1232	NM_016021	Huesken	UBE2J1	51465	CCUGAGAUGCUCAAACAGAuu	UCUGUUUGAGCAUCUCAGG	-2.4	-3.3	-2	0	-3	2	-38.2	39.2	-8	2	III	47.4	38.8	56	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1233	NM_016021	Huesken	UBE2J1	51465	CCCACUUCAAAUCGACCAUua	AUGGUCGAUUUGAAGUGGG	-1.1	-3.3	1.6	-1	-3	3	-37.2	62.4	1.8	3	III	47.4	34.6	56.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1234	NM_016021	Huesken	UBE2J1	51465	CACUUCAAAUCGACCAUUAgc	UAAUGGUCGAUUUGAAGUG	-1.3	-2.1	1.6	-1	-4	2	-32.8	68.4	-10.7	5	II	36.8	41.4	46.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1235	NM_016021	Huesken	UBE2J1	51465	AAUCGACCAUUAGCCGUUAgg	UAACGGCUAAUGGUCGAUU	-1.3	-0.9	-4.2	2	0	4	-35.7	51.1	-3.8	4	II	42.1	42.4	84	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1236	NM_016021	Huesken	UBE2J1	51465	UAAUGCUUGGUGGUUUCAUgg	AUGAAACCACCAAGCAUUA	-1.1	-1.3	1.7	2	3	2	-34.4	78	-1.6	7	II	36.8	62.4	68.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1237	NM_016021	Huesken	UBE2J1	51465	CAUGGGAUACUCUGGUGGCag	GCCACCAGAGUAUCCCAUG	-3.4	-2.1	1.9	-2	2	3	-41.9	48.5	3.1	2	II	57.9	49.6	53.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1238	NM_016021	Huesken	UBE2J1	51465	ACUAUCCGCCCGUGAUAAAcu	UUUAUCACGGGCGGAUAGU	-0.9	-2.2	-1.2	1	-1	7	-38.1	54.2	-6.1	4	II	47.4	31.6	51.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1239	NM_016021	Huesken	UBE2J1	51465	ACUCCUCCAUCAAAAUCGGag	CCGAUUUUGAUGGAGGAGU	-3.3	-2.2	0.1	2	4	3	-37.4	54.8	-4.9	3	II	47.4	51.4	48	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1240	NM_016021	Huesken	UBE2J1	51465	GGCUGCGCAUGGUAAUGAUcu	AUCAUUACCAUGCGCAGCC	-1.1	-3.3	1.5	0	-2	4	-39.8	48	-4	2	III	52.6	21.7	55.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1241	NM_005339	Huesken	HIP2	3093	GAGCUGUCUGUUUGAACAUuu	AUGUUCAAACAGACAGCUC	-1.1	-2.4	-1	1	-1	2	-35.7	59	-1	2	III	42.1	40	64.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1242	NM_005339	Huesken	HIP2	3093	CUGUCUGUUUGAACAUUUCgg	GAAAUGUUCAAACAGACAG	-2.4	-2.1	-1	-1	-1	1	-32	76.5	2.8	3	II	36.8	54.6	76.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1243	NM_005339	Huesken	HIP2	3093	UCUGUUUGAACAUUUCGGGau	CCCGAAAUGUUCAAACAGA	-3.3	-2.4	0.4	1	5	4	-34.6	81.9	0	7	Ia	42.1	71.6	92.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1244	NM_005339	Huesken	HIP2	3093	UUUGAACAUUUCGGGAUUUug	AAAUCCCGAAAUGUUCAAA	-0.9	-0.9	0.9	-1	1	4	-31.1	64.6	-3.6	7	II	31.6	56.5	73.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1245	NM_005339	Huesken	HIP2	3093	UUUCGGGAUUUUGUUUGUAcu	UACAAACAAAAUCCCGAAA	-1.3	-0.9		1	2	4	-31.1	71.6	1.6	6	II	31.6	57.2	66.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1246	NM_005339	Huesken	HIP2	3093	UUCGGGAUUUUGUUUGUACug	GUACAAACAAAAUCCCGAA	-2.2	-0.9	1.2	0	3	4	-32.4	81.7	9.7	6	II	36.8	69.2	73.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1247	NM_005339	Huesken	HIP2	3093	CGGGAUUUUGUUUGUACUGau	CAGUACAAACAAAAUCCCG	-2.1	-2.4	1	-1	-1	4	-33.3	65.6	3.7	2	II	42.1	50.1	70.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1248	NM_005339	Huesken	HIP2	3093	UUGUUUGUACUGAUUUGCUac	AGCAAAUCAGUACAAACAA	-2.1	-0.9	0.9	0	3	2	-31.9	89.4	-4.2	7	II	31.6	71.4	77.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1249	NM_005339	Huesken	HIP2	3093	UUGUACUGAUUUGCUACUAca	UAGUAGCAAAUCAGUACAA	-1.3	-0.9	0.8	1	0	2	-32.7	79.5	2	7	II	31.6	60.1	87.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1250	NM_005339	Huesken	HIP2	3093	UGUACUGAUUUGCUACUACag	GUAGUAGCAAAUCAGUACA	-2.2	-2.1	0.8	0	3	2	-34	82.2	12.1	7	Ib	36.8	64.6	92.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1251	NM_005339	Huesken	HIP2	3093	ACUGAUUUGCUACUACAGCau	GCUGUAGUAGCAAAUCAGU	-3.4	-2.2	-2	3	4	2	-36	68.1	14.8	4	Ia	42.1	63.3	87.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1252	NM_005339	Huesken	HIP2	3093	GAUUUGCUACUACAGCAUCcu	GAUGCUGUAGUAGCAAAUC	-2.4	-2.4	-3	0	1	2	-35.2	66	9.8	3	II	42.1	49.7	65.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1253	NM_005339	Huesken	HIP2	3093	UUUGCUACUACAGCAUCCUgu	AGGAUGCUGUAGUAGCAAA	-2.1	-0.9	-3	0	3	2	-37.1	72.7	-6.3	6	II	42.1	71.9	92.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1254	NM_005339	Huesken	HIP2	3093	UUGCUACUACAGCAUCCUGug	CAGGAUGCUGUAGUAGCAA	-2.1	-0.9	-3	1	3	2	-38.3	66.2	4.7	4	Ib	47.4	63.1	93	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1255	NM_005339	Huesken	HIP2	3093	UGCUACUACAGCAUCCUGUgg	ACAGGAUGCUGUAGUAGCA	-2.2	-2.1	-2.4	2	1	2	-39.6	76.3	-3.9	7	II	47.4	62.8	89.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1256	NM_005339	Huesken	HIP2	3093	CUACAGCAUCCUGUGGAUCau	GAUCCACAGGAUGCUGUAG	-2.4	-2.1	-2.7	0	1	2	-39.8	50.5	11.1	2	II	52.6	48.5	67.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1257	NM_005339	Huesken	HIP2	3093	AGCAUCCUGUGGAUCAUCUgg	AGAUGAUCCACAGGAUGCU	-2.1	-2.1	-1.7	2	1	2	-39.8	68.4	-4.2	4	II	47.4	49.3	68	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1258	NM_005339	Huesken	HIP2	3093	CAUCCUGUGGAUCAUCUGGcu	CCAGAUGAUCCACAGGAUG	-3.3	-2.1	-1.7	1	1	2	-39.7	67.1	5.7	3	II	52.6	53.5	66.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1259	NM_005339	Huesken	HIP2	3093	AUCCUGUGGAUCAUCUGGCuc	GCCAGAUGAUCCACAGGAU	-3.4	-1.1	-1	4	5	3	-41	63.6	4.8	5	Ib	52.6	68.5	74.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1260	NM_005339	Huesken	HIP2	3093	UGUGGAUCAUCUGGCUCUGca	CAGAGCCAGAUGAUCCACA	-2.1	-2.1	1.3	0	3	3	-40.8	54.3	0.7	5	Ib	52.6	55	82.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1261	NM_005339	Huesken	HIP2	3093	AUCUGGCUCUGCAGCUGCCaa	GGCAGCUGCAGAGCCAGAU	-3.3	-1.1	-3.5	1	4	3	-45	49	2.5	2	II	63.2	54.3	81.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1262	NM_005339	Huesken	HIP2	3093	UGGCUCUGCAGCUGCCAAUag	AUUGGCAGCUGCAGAGCCA	-1.1	-2.1	-3.6	2	-1	3	-43.5	58.2	-6.3	4	II	57.9	50.7	85	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1263	NM_005339	Huesken	HIP2	3093	CUCUGCAGCUGCCAAUAGUgc	ACUAUUGGCAGCUGCAGAG	-2.2	-2.1	-1.3	0	-2	3	-40.3	53.8	-5.9	2	III	52.6	40.1	62	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1264	NM_005339	Huesken	HIP2	3093	UAGUGCUUGCAAUGACAAUaa	AUUGUCAUUGCAAGCACUA	-1.1	-1.3	-0.5	1	0	2	-34.5	73.6	-1.7	6	II	36.8	55.4	85.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1265	NM_005339	Huesken	HIP2	3093	AGUGCUUGCAAUGACAAUAau	UAUUGUCAUUGCAAGCACU	-1.3	-2.1	-0.5	3	-1	2	-34.5	74.2	1.6	5	II	36.8	54	89.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1266	NM_005339	Huesken	HIP2	3093	UGACAAUAAUACCGUGCGGag	CCGCACGGUAUUAUUGUCA	-3.3	-2.1	-0.3	1	4	4	-36.7	58.2	5.1	6	Ia	47.4	58.9	63.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1267	NM_005339	Huesken	HIP2	3093	AUACCGUGCGGAGAGUCAUug	AUGACUCUCCGCACGGUAU	-1.1	-1.1	-0.4	4	2	4	-40.5	50	-4	5	II	52.6	51.5	85.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1268	NM_005339	Huesken	HIP2	3093	UGCGGAGAGUCAUUGCAGCug	GCUGCAAUGACUCUCCGCA	-3.4	-2.1	0	1	3	4	-42	49.5	7.4	3	II	57.9	57.1	87.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1269	NM_005339	Huesken	HIP2	3093	GGAGAGUCAUUGCAGCUGCcc	GCAGCUGCAAUGACUCUCC	-3.4	-3.3	-1.3	1	1	2	-41.7	44.9	12.5	2	II	57.9	46.8	47.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1270	NM_005339	Huesken	HIP2	3093	GAGAGUCAUUGCAGCUGCCca	GGCAGCUGCAAUGACUCUC	-3.3	-2.4	-1.3	-1	2	3	-41.7	46.1	2.5	0	II	57.9	45	57.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1271	NM_005339	Huesken	HIP2	3093	GAGUCAUUGCAGCUGCCCAuu	UGGGCAGCUGCAAUGACUC	-2.1	-2.4	-1.3	2	0	4	-42.6	57.6	3.3	1	II	57.9	38.7	44.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1272	NM_005339	Huesken	HIP2	3093	AUUGCAGCUGCCCAUUGAUcu	AUCAAUGGGCAGCUGCAAU	-1.1	-1.1	-1.3	1	2	4	-39	57.3	-6.3	4	II	47.4	47.7	48.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1273	NM_005339	Huesken	HIP2	3093	GCUGCCCAUUGAUCUUUCAgg	UGAAAGAUCAAUGGGCAGC	-2.1	-3.4	0.5	0	-2	4	-38.1	58	-3.8	2	III	47.4	28.5	57.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1274	NM_005339	Huesken	HIP2	3093	CUGCCCAUUGAUCUUUCAGga	CUGAAAGAUCAAUGGGCAG	-2.1	-2.1	0.4	0	1	4	-36.8	73.3	8.1	2	II	47.4	49.4	79.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1275	NM_005339	Huesken	HIP2	3093	UCUUUCAGGAUAUCCAAACaa	GUUUGGAUAUCCUGAAAGA	-2.2	-2.4	-1	1	2	2	-33.9	82.9	7.4	7	Ia	36.8	69.9	87.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1276	NM_005339	Huesken	HIP2	3093	CUUUCAGGAUAUCCAAACAaa	UGUUUGGAUAUCCUGAAAG	-2.1	-2.1	-1	-1	-2	2	-33.6	71.6	2	3	II	36.8	42.4	58.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1277	NM_005339	Huesken	HIP2	3093	UUCAGGAUAUCCAAACAAAua	UUUGUUUGGAUAUCCUGAA	-0.9	-0.9	-1	0	-1	2	-32.4	67.3	-11	5	II	31.6	56.7	78.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1278	NM_005339	Huesken	HIP2	3093	UAUCCAAACAAAUAGCCCCug	GGGGCUAUUUGUUUGGAUA	-3.3	-1.3	-0.5	2	5	5	-35.9	79.3	9.7	7	Ia	42.1	80.5	81.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1279	NM_005339	Huesken	HIP2	3093	AUCCAAACAAAUAGCCCCUgu	AGGGGCUAUUUGUUUGGAU	-2.1	-1.1	-0.5	1	2	5	-36.7	61.8	1.5	6	II	42.1	58.6	71	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1280	NM_005339	Huesken	HIP2	3093	AAUAGCCCCUGUGACGGAAcu	UUCCGUCACAGGGGCUAUU	-0.9	-0.9	-2.1	2	1	5	-40.8	53.5	-0.7	4	II	52.6	39.4	55.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1281	NM_005339	Huesken	HIP2	3093	UGACGGAACUAAUAUUAGGau	CCUAAUAUUAGUUCCGUCA	-3.3	-2.1	1	2	3	3	-33.3	69.6	2.3	5	II	36.8	67.6	74.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1282	NM_005339	Huesken	HIP2	3093	ACGGAACUAAUAUUAGGAUgc	AUCCUAAUAUUAGUUCCGU	-1.1	-2.2	1	1	1	3	-32.3	63.4	1.1	4	II	31.6	43.7	53.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1283	NM_005339	Huesken	HIP2	3093	AACUAAUAUUAGGAUGCCAua	UGGCAUCCUAAUAUUAGUU	-2.1	-0.9	1	2	1	3	-32.9	69.9	1.3	6	II	31.6	52.7	61.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1284	NM_005339	Huesken	HIP2	3093	UAUUAGGAUGCCAUAUUUUag	AAAAUAUGGCAUCCUAAUA	-0.9	-1.3	1.2	0	2	3	-30.6	83.4	-6.2	9	II	26.3	67	67.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1285	NM_005339	Huesken	HIP2	3093	UAGGAUGCCAUAUUUUAGUga	ACUAAAAUAUGGCAUCCUA	-2.2	-1.3	1.2	1	2	3	-32.9	84.5	1.1	7	II	31.6	71.8	76	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1286	NM_005339	Huesken	HIP2	3093	CAUAUUUUAGUGAUAAACCgg	GGUUUAUCACUAAAAUAUG	-3.3	-2.1	1	0	2	2	-28.1	93.3	5.1	5	II	26.3	71.4	81.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1287	NM_005339	Huesken	HIP2	3093	UAUUUUAGUGAUAAACCGGac	CCGGUUUAUCACUAAAAUA	-3.3	-1.3	0.7	0	5	4	-30.6	90	2.7	8	Ia	31.6	80.7	89.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1288	NM_005339	Huesken	HIP2	3093	AUUUUAGUGAUAAACCGGAcc	UCCGGUUUAUCACUAAAAU	-2.4	-1.1	0.7	2	2	4	-31.7	70.3	-6.3	8	II	31.6	60.7	73	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1289	NM_005339	Huesken	HIP2	3093	AUUAAAUGGGUAUGUUUCUgg	AGAAACAUACCCAUUUAAU	-2.1	-1.1	3.1	2	2	3	-30.1	79.4	-1.3	8	II	26.3	62	72.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1290	NM_005339	Huesken	HIP2	3093	UAAAUGGGUAUGUUUCUGGua	CCAGAAACAUACCCAUUUA	-3.3	-1.3	3.1	0	5	3	-33.5	86.6	2.3	10	Ia	36.8	81.1	72.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1291	NM_005339	Huesken	HIP2	3093	AUGGGUAUGUUUCUGGUAUuu	AUACCAGAAACAUACCCAU	-1.1	-1.1	4.4	2	1	3	-35	75.1	3.8	5	II	36.8	54.8	76.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1292	NM_005339	Huesken	HIP2	3093	UUUUAUCUCUAGUUGGUAUcu	AUACCAACUAGAGAUAAAA	-1.1	-0.9	2.8	1	2	2	-30.6	101.7	3.4	8	II	26.3	62.2	78.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1293	NM_005339	Huesken	HIP2	3093	UCUAGUUGGUAUCUUCCUCcu	GAGGAAGAUACCAACUAGA	-2.4	-2.4	-0.9	2	4	2	-36.6	83.3	17.5	6	Ia	42.1	67.7	79.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1294	NM_005339	Huesken	HIP2	3093	UAGUUGGUAUCUUCCUCCUuc	AGGAGGAAGAUACCAACUA	-2.1	-1.3	-0.9	0	2	2	-37.5	82	-3.3	7	II	42.1	66.4	75.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1295	NM_005339	Huesken	HIP2	3093	AGUUGGUAUCUUCCUCCUUca	AAGGAGGAAGAUACCAACU	-0.9	-2.1	-0.9	2	1	2	-37.1	67.6	1.5	5	II	42.1	51.2	68.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1296	NM_005339	Huesken	HIP2	3093	UUGGUAUCUUCCUCCUUCAua	UGAAGGAGGAAGAUACCAA	-2.1	-0.9	-0.9	1	0	2	-37.3	76.8	-8.5	7	II	42.1	64.7	82.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1297	NM_005339	Huesken	HIP2	3093	CUUCCUCCUUCAUAUGGUGug	CACCAUAUGAAGGAGGAAG	-2.1	-2.1	-0.5	0	1	2	-37.2	62.4	-4.4	2	II	47.4	47.1	69.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1298	NM_005339	Huesken	HIP2	3093	CUCCUUCAUAUGGUGUGUCug	GACACACCAUAUGAAGGAG	-2.4	-2.1	-0.5	0	1	2	-37.4	63.1	7.7	3	II	47.4	51.3	64.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1299	NM_005339	Huesken	HIP2	3093	UCCUUCAUAUGGUGUGUCUgg	AGACACACCAUAUGAAGGA	-2.1	-2.4	-0.5	-1	0	2	-37.4	78.1	-4	7	II	42.1	53.3	81	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1300	NM_005339	Huesken	HIP2	3093	CCUUCAUAUGGUGUGUCUGga	CAGACACACCAUAUGAAGG	-2.1	-3.3	0.6	0	1	2	-37.1	68	3.4	3	II	47.4	44.8	72.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1301	NM_005339	Huesken	HIP2	3093	UUCAUAUGGUGUGUCUGGAgg	UCCAGACACACCAUAUGAA	-2.4	-0.9	1.8	2	2	2	-37.4	74.8	1.6	7	II	42.1	56.9	73.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1302	NM_005339	Huesken	HIP2	3093	CAUAUGGUGUGUCUGGAGGuc	CCUCCAGACACACCAUAUG	-3.3	-2.1	2.9	0	2	2	-39.5	68.4	5.8	5	II	52.6	51.9	66.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1303	NM_005339	Huesken	HIP2	3093	UGGUGUGUCUGGAGGUCCUgc	AGGACCUCCAGACACACCA	-2.1	-2.1	-1.7	0	1	2	-43.9	53.7	-6.6	3	II	57.9	52.9	74.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1304	NM_005339	Huesken	HIP2	3093	UGUCUGGAGGUCCUGCUAUuu	AUAGCAGGACCUCCAGACA	-1.1	-2.1	-1.7	2	1	2	-42	57.5	-1.6	6	II	52.6	52.9	69.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1305	NM_005339	Huesken	HIP2	3093	GUCUGGAGGUCCUGCUAUUuc	AAUAGCAGGACCUCCAGAC	-0.9	-2.2	-1.7	0	-2	2	-40.8	46.3	-8.7	2	III	52.6	33.2	56.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1306	NM_005339	Huesken	HIP2	3093	UCUGGAGGUCCUGCUAUUUcu	AAAUAGCAGGACCUCCAGA	-0.9	-2.4	-1.7	0	0	2	-39.5	55.3	-3.3	5	II	47.4	50.6	65.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1307	NM_005339	Huesken	HIP2	3093	AGGUCCUGCUAUUUCUCCUcu	AGGAGAAAUAGCAGGACCU	-2.1	-2.1	0.8	3	2	2	-39.5	80.7	3.7	4	II	47.4	53.8	69.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1308	NM_005339	Huesken	HIP2	3093	GGUCCUGCUAUUUCUCCUCuu	GAGGAGAAAUAGCAGGACC	-2.4	-3.3	2.2	1	1	2	-39.8	65.4	10.4	3	II	52.6	48.7	54.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1309	NM_005339	Huesken	HIP2	3093	CUAUUUCUCCUCUUAAUUCug	GAAUUAAGAGGAGAAAUAG	-2.4	-2.1	3.1	0	1	2	-30.6	90.6	5.4	5	II	31.6	62.5	74.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1310	NM_005339	Huesken	HIP2	3093	UCCUCUUAAUUCUGUAAAAuu	UUUUACAGAAUUAAGAGGA	-0.9	-2.4	0.8	0	-2	2	-30.2	83	-6.1	5	II	26.3	48.2	47.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1311	NM_005339	Huesken	HIP2	3093	UGUAAAAUUCUCAUCUACAag	UGUAGAUGAGAAUUUUACA	-2.1	-2.1	-2.3	0	1	1	-30.5	82.5	-3.7	6	II	26.3	65.6	89.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1312	NM_005339	Huesken	HIP2	3093	GUAAAAUUCUCAUCUACAAga	UUGUAGAUGAGAAUUUUAC	-0.9	-2.2	-0.6	2	-1	1	-29.3	75.6	-3.4	5	II	26.3	43.1	55.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1313	NM_005339	Huesken	HIP2	3093	UAAAAUUCUCAUCUACAAGau	CUUGUAGAUGAGAAUUUUA	-2.1	-1.3	0.2	1	4	1	-29.2	98.2	12.8	8	Ia	26.3	76.4	91.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1314	NM_005339	Huesken	HIP2	3093	AAAAUUCUCAUCUACAAGAuc	UCUUGUAGAUGAGAAUUUU	-2.4	-0.9	-1.4	2	1	1	-30.3	87.4	-6.1	6	II	26.3	66.5	84.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1315	NM_005339	Huesken	HIP2	3093	AAAUUCUCAUCUACAAGAUcu	AUCUUGUAGAUGAGAAUUU	-1.1	-0.9	-1.7	2	2	1	-30.5	85.6	-5.9	6	II	26.3	56.4	81.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1316	NM_005339	Huesken	HIP2	3093	UUCUCAUCUACAAGAUCUAcu	UAGAUCUUGUAGAUGAGAA	-1.3	-0.9	-1.7	0	0	1	-33.4	74.3	-8.7	6	II	31.6	58.1	85.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1317	NM_005339	Huesken	HIP2	3093	CUCAUCUACAAGAUCUACUuu	AGUAGAUCUUGUAGAUGAG	-2.1	-2.1	-0.2	1	-1	1	-34.4	83.5	-3.9	5	II	36.8	58.6	88.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1318	NM_005339	Huesken	HIP2	3093	UCAUCUACAAGAUCUACUUua	AAGUAGAUCUUGUAGAUGA	-0.9	-2.4	-0.2	0	1	1	-33.2	87.7	-4	7	II	31.6	65.7	88.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1319	NM_005339	Huesken	HIP2	3093	CUACAAGAUCUACUUUAAUuu	AUUAAAGUAGAUCUUGUAG	-1.1	-2.1	0.6	0	-1	1	-29.4	66.1	1.5	4	II	26.3	44.3	45.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1320	NM_053656	Huesken	P2rx2	22953	GGUCUUUGUCCCAUAUGCUgg	AGCAUAUGGGACAAAGACC	-2.1	-3.3	-0.1	2	1	3	-38.3	60.9	-8.9	3	II	47.4	42.5	53.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1321	NM_053656	Huesken	P2rx2	22953	GUCUUUGUCCCAUAUGCUGgc	CAGCAUAUGGGACAAAGAC	-2.1	-2.2	1.1	1	1	3	-37.1	68.3	-2.4	4	II	47.4	50.7	51.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1322	NM_053656	Huesken	P2rx2	22953	GUCCCAUAUGCUGGCCAAGug	CUUGGCCAGCAUAUGGGAC	-2.1	-2.2	-2.4	1	0	4	-41.6	43.4	0.7	0	II	57.9	36.7	52	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1323	NM_053656	Huesken	P2rx2	22953	GCCAAGUGUGUCCACCACCug	GGUGGUGGACACACUUGGC	-3.3	-3.4	-3	1	0	3	-43.5	41.2	10.2	1	II	63.2	49.1	52.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1324	NM_053656	Huesken	P2rx2	22953	ACCACCUGCUCAGUCAGAGca	CUCUGACUGAGCAGGUGGU	-2.1	-2.2	-1.8	3	3	2	-42.7	53.7	0	2	II	57.9	47.3	46.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1325	NM_053656	Huesken	P2rx2	22953	CUCAGUCAGAGCAGAGAUGga	CAUCUCUGCUCUGACUGAG	-2.1	-2.1	-1.1	-1	-1	2	-39.7	47.9	-6.9	2	II	52.6	44.8	42.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1326	NM_053656	Huesken	P2rx2	22953	CGAGGAGACUGGACAGCCAgu	UGGCUGUCCAGUCUCCUCG	-2.1	-2.4	-2.9	0	-2	3	-44.4	25.5	-8.3	0	III	63.2	32.1	67.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1327	NM_053656	Huesken	P2rx2	22953	UGAUGGAGGGCUGGGUGGCug	GCCACCCAGCCCUCCAUCA	-3.4	-2.1	0.2	0	4	4	-47.3	38.9	8.1	5	Ib	68.4	56.6	60.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1328	NM_053656	Huesken	P2rx2	22953	UGGAGGGCUGGGUGGCUGAuc	UCAGCCACCCAGCCCUCCA	-2.4	-2.1	0	-1	-1	4	-48.3	38.3	-3.8	5	II	68.4	45.2	51.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1329	NM_053656	Huesken	P2rx2	22953	GGUGGCUGAUCCUGGGAGUag	ACUCCCAGGAUCAGCCACC	-2.2	-3.3	-0.9	0	-1	3	-45.2	38.2	-8.7	1	III	63.2	27.5	44.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1330	NM_053656	Huesken	P2rx2	22953	GCUGAUCCUGGGAGUAGUGac	CACUACUCCCAGGAUCAGC	-2.1	-3.4	0.1	-1	1	3	-42	39.4	0.1	1	II	57.9	34.6	46.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1331	NM_053656	Huesken	P2rx2	22953	GAUCCUGGGAGUAGUGACUag	AGUCACUACUCCCAGGAUC	-2.1	-2.4	0.1	1	0	3	-41.1	55.1	-3.5	4	III	52.6	41.7	64.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1332	NM_053656	Huesken	P2rx2	22953	CUGGCCCAAGACAAGGGCAag	UGCCCUUGUCUUGGGCCAG	-2.1	-2.1	-6.9	-1	-2	5	-44.4	37.3	-8.4	-1	III	63.2	37.2	37	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1333	NM_053656	Huesken	P2rx2	22953	AAGACAAGGGCAAGGGUCAca	UGACCCUUGCCCUUGUCUU	-2.1	-0.9	-0.1	1	0	4	-41.1	44.9	-8.7	6	II	52.6	48.6	53.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1334	NM_053656	Huesken	P2rx2	22953	UCACAGGCCAUCUACUUGAgg	UCAAGUAGAUGGCCUGUGA	-2.4	-2.4	0.7	2	0	4	-39.6	58.5	-3.4	8	II	47.4	60.3	67.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1335	NM_053656	Huesken	P2rx2	22953	UUGUCGAACUUCUUAUGGCug	GCCAUAAGAAGUUCGACAA	-3.4	-0.9	1.6	1	5	3	-35.1	81	7.4	6	Ib	42.1	73.9	88.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1336	NM_053656	Huesken	P2rx2	22953	UAUGGCUGUAGAGCUUGUUuu	AACAAGCUCUACAGCCAUA	-0.9	-1.3	-1	1	2	3	-37.1	69.6	-4	6	II	42.1	61.8	76.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1337	NM_053656	Huesken	P2rx2	22953	CCAGUCACACAGGAAGGAGcc	CUCCUUCCUGUGUGACUGG	-2.1	-3.3	1	-1	0	2	-41.4	39.3	0.3	2	II	57.9	38.8	47.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1338	NM_053656	Huesken	P2rx2	22953	GGAGCCCACCCCGAUGGAGgu	CUCCAUCGGGGUGGGCUCC	-2.1	-3.3	-4.5	1	1	5	-47.8	25.2	-4.7	-1	II	73.7	27.9	38.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1339	NM_053656	Huesken	P2rx2	22953	GAGGUCAGAGCAGUGGCCAga	UGGCCACUGCUCUGACCUC	-2.1	-2.4	-0.5	0	0	4	-45.1	37.2	-3.8	2	III	63.2	38	57	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1340	NM_053656	Huesken	P2rx2	22953	GCAGUGGCCAGAUUGAUGAug	UCAUCAAUCUGGCCACUGC	-2.4	-3.4	1.4	1	-1	4	-40.6	53.6	-1.4	5	III	52.6	39.7	43.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1341	NM_053656	Huesken	P2rx2	22953	GGGAAUGAGACUGAAUUUCcc	GAAAUUCAGUCUCAUUCCC	-2.4	-3.3	1.8	1	-1	3	-35	59.9	10.8	5	II	42.1	47.2	39.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1342	NM_053656	Huesken	P2rx2	22953	GAAUGAGACUGAAUUUCCCug	GGGAAAUUCAGUCUCAUUC	-3.3	-2.4	-2.1	1	4	3	-35	64	7.1	3	II	42.1	54.3	72.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1343	NM_053656	Huesken	P2rx2	22953	GAGACUGAAUUUCCCUGCCug	GGCAGGGAAAUUCAGUCUC	-3.3	-2.4	-0.6	0	2	3	-39.4	63.9	12.8	3	II	52.6	52.5	51.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1344	NM_053656	Huesken	P2rx2	22953	CCAUGCACGAUAACAUCGAuu	UCGAUGUUAUCGUGCAUGG	-2.4	-3.3	-1.7	0	-2	2	-37	46.3	-8.3	3	III	47.4	40.8	57.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1345	NM_053656	Huesken	P2rx2	22953	AUUCGAAUCCCAUAGGCUUug	AAGCCUAUGGGAUUCGAAU	-0.9	-1.1	-0.8	3	2	3	-36.5	61.9	-6.3	5	II	42.1	55.8	76	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1346	NM_053656	Huesken	P2rx2	22953	GAUGAGAGUUCGAGUGGUGgu	CACCACUCGAACUCUCAUC	-2.1	-2.4	0.7	-1	2	2	-38.9	40.9	-2.2	4	II	52.6	41.4	64.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1347	NM_053656	Huesken	P2rx2	22953	GAGUUCGAGUGGUGGUAGUgc	ACUACCACCACUCGAACUC	-2.2	-2.4		0	-1	2	-39.9	53.8	-4	4	III	52.6	32.9	43.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1348	NM_053656	Huesken	P2rx2	22953	GUAGUGCCGUUUAUCUUGUaa	ACAAGAUAAACGGCACUAC	-2.2	-2.2	2.8	1	1	4	-35.1	63.2	-1.2	4	III	42.1	46.1	50.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1349	NM_053656	Huesken	P2rx2	22953	UAUCUUGUAAUACUUGGCAaa	UGCCAAGUAUUACAAGAUA	-2.1	-1.3	1.7	1	3	3	-32.8	86.5	1	8	II	31.6	69.4	76.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1350	NM_053656	Huesken	P2rx2	22953	AUCUUGUAAUACUUGGCAAac	UUGCCAAGUAUUACAAGAU	-0.9	-1.1	1.8	2	1	3	-32.4	84.6	-1.5	6	II	31.6	50.6	56.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1351	NM_053656	Huesken	P2rx2	22953	GGCAAACCUGAAGUUGUAGcc	CUACAACUUCAGGUUUGCC	-2.1	-3.3	-0.1	0	0	3	-36.5	53.5	7.3	3	II	47.4	33.1	57	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1352	NM_053656	Huesken	P2rx2	22953	AGCCUGAGGAGGCAGGGUCau	GACCCUGCCUCCUCAGGCU	-2.4	-2.1	-4.5	3	2	3	-47.4	40.5	9.8	3	II	68.4	50.5	61.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1353	NM_053656	Huesken	P2rx2	22953	UUGCACUCUGAUUCAGACAag	UGUCUGAAUCAGAGUGCAA	-2.1	-0.9	-1.4	2	0	2	-37.1	76.6	4.3	5	II	42.1	64.5	80.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1354	NM_053656	Huesken	P2rx2	22953	ACAAGUCCAGGUCACAGUUcc	AACUGUGACCUGGACUUGU	-0.9	-2.2	1.5	1	1	2	-38.9	58.1	1.5	4	II	47.4	48.2	38.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1355	NM_053656	Huesken	P2rx2	22953	GUCCAGGUCACAGUUCCAGuu	CUGGAACUGUGACCUGGAC	-2.1	-2.2	-0.1	2	2	2	-41.5	45.4	2.7	3	II	57.9	43.9	70.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1356	NM_053656	Huesken	P2rx2	22953	GUUCCAGUUGAUGAUGACUcc	AGUCAUCAUCAACUGGAAC	-2.1	-2.2	0.9	1	0	2	-36.1	63.3	1.4	3	III	42.1	44.9	33.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1357	NM_053656	Huesken	P2rx2	22953	AUGAUGACUCCAAUGACACcg	GUGUCAUUGGAGUCAUCAU	-2.2	-1.1	0.4	1	4	2	-36.3	69.5	4.8	6	Ia	42.1	67.3	59	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1358	NM_053656	Huesken	P2rx2	22953	GUUCUGUGAAGUUCUCUCCug	GGAGAGAACUUCACAGAAC	-3.3	-2.2	-2.1	2	2	2	-37.2	79.8	10.4	5	II	47.4	60.2	61.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1359	NM_053656	Huesken	P2rx2	22953	GUUCUCUCCUGCCUUCUCAac	UGAGAAGGCAGGAGAGAAC	-2.1	-2.2	1.7	3	0	3	-40.7	68.7	-1.4	5	II	52.6	43.2	32.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1360	NM_053656	Huesken	P2rx2	22953	UCCUGCCUUCUCAACAAUGaa	CAUUGUUGAGAAGGCAGGA	-2.1	-2.4	-1.5	0	1	3	-37.9	61.6	-4.9	3	II	47.4	60.1	61.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1361	NM_053656	Huesken	P2rx2	22953	CAACAAUGAAACCCAGCCUga	AGGCUGGGUUUCAUUGUUG	-2.1	-2.1	1.1	1	0	3	-37.4	56.4	-0.9	5	II	47.4	50.6	64.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1362	NM_053656	Huesken	P2rx2	22953	AUGGGUCAGAGUCCUGAUCaa	GAUCAGGACUCUGACCCAU	-2.4	-1.1	-2.5	2	2	3	-41.1	62.4	12.8	3	II	52.6	58.9	81.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1363	NM_053656	Huesken	P2rx2	22953	AUGUGCAAUGCUUGAGGUAgu	UACCUCAAGCAUUGCACAU	-1.3	-1.1	0.4	0	0	2	-36.9	59.9	-3.1	5	II	42.1	46	72.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1364	NM_053656	Huesken	P2rx2	22953	UCACUCUUCUGGCUUGCAAug	UUGCAAGCCAGAAGAGUGA	-0.9	-2.4	1.7	3	1	3	-39	69.8	1	6	II	47.4	49	72.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1365	NM_053656	Huesken	P2rx2	22953	GAACUUGAACUUGGGGUAGug	CUACCCCAAGUUCAAGUUC	-2.1	-2.4	2.2	0	1	4	-36.7	53.7	3	5	II	47.4	42.7	62.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1366	NM_053656	Huesken	P2rx2	22953	UGGAUGCUGUUCUUGAUGAgg	UCAUCAAGAACAGCAUCCA	-2.4	-2.1	1.4	1	0	2	-37.2	73	-3.8	6	II	42.1	54.6	53.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1367	NM_053656	Huesken	P2rx2	22953	GAUGAGGAUGGUGAAAUUUgg	AAAUUUCACCAUCCUCAUC	-0.9	-2.4	4.3	0	-1	2	-33.7	57.3	1.8	5	III	36.8	43.4	23.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1368	NM_053656	Huesken	P2rx2	22953	CCCAGAAAAUGGUUGUCAGaa	CUGACAACCAUUUUCUGGG	-2.1	-3.3	-1.9	-1	0	3	-36.4	58.2	0.3	1	II	47.4	36.8	40.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1369	NM_053656	Huesken	P2rx2	22953	GAAAAUGGUUGUCAGAAGUuc	ACUUCUGACAACCAUUUUC	-2.2	-2.4	1.8	0	0	2	-33.2	68	4.2	5	II	36.8	47.6	33.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1370	NM_053656	Huesken	P2rx2	22953	GUUCCAUCCUCCACCGGGCac	GCCCGGUGGAGGAUGGAAC	-3.4	-2.2	-1.5	3	3	6	-45.5	45.8	0.1	1	II	68.4	47.4	48.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1371	NM_053656	Huesken	P2rx2	22953	GACACCUCGCAGGUCUUGGag	CCAAGACCUGCGAGGUGUC	-3.3	-2.4	-2.2	2	2	3	-43	59.2	4.6	2	II	63.2	45.9	68.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1372	NM_053656	Huesken	P2rx2	22953	AUAGGGUACACAGUGCCCUgu	AGGGCACUGUGUACCCUAU	-2.1	-1.1	-3.6	3	4	4	-41.7	52.9	-4	5	II	52.6	64.9	55	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1373	NM_053656	Huesken	P2rx2	22953	AGUGCCCUGUGCGAAUCCCau	GGGAUUCGCACAGGGCACU	-3.3	-2.1	-1.2	2	4	4	-44.1	47	5.1	1	II	63.2	50.1	66	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1374	NM_053656	Huesken	P2rx2	22953	UGCGAAUCCCAUUGCCUUGca	CAAGGCAAUGGGAUUCGCA	-2.1	-2.1	-0.1	1	1	3	-39.3	65.1	8	6	Ib	52.6	58.8	64.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1375	NM_053656	Huesken	P2rx2	22953	CAUUGCCUUGCAUGUCCAGcu	CUGGACAUGCAAGGCAAUG	-2.1	-2.1	-0.4	-2	1	3	-38.8	55	-4.4	3	II	52.6	40.3	55.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1376	NM_053656	Huesken	P2rx2	22953	CCUUGCAUGUCCAGCUGUCcg	GACAGCUGGACAUGCAAGG	-2.4	-3.3	-1.4	-1	0	2	-41.4	45.4	-1.9	1	II	57.9	39.6	35.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1377	NM_053656	Huesken	P2rx2	22953	UCUGAAUGGCAGGUAGAGCug	GCUCUACCUGCCAUUCAGA	-3.4	-2.4	-0.5	2	4	3	-40.8	56.3	14.7	6	Ia	52.6	61.1	79.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1378	NM_053656	Huesken	P2rx2	22953	GAAUGGCAGGUAGAGCUGUga	ACAGCUCUACCUGCCAUUC	-2.2	-2.4	-0.5	1	0	3	-40.6	38.2	-4	4	III	52.6	40	42.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1379	NM_053656	Huesken	P2rx2	22953	UGGCAGGUAGAGCUGUGAAcc	UUCACAGCUCUACCUGCCA	-0.9	-2.1	-0.5	1	0	3	-41.6	53.3	6	5	II	52.6	43.4	51.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1380	NM_053656	Huesken	P2rx2	22953	AUGUUCCCAAGGUCUGGGAag	UCCCAGACCUUGGGAACAU	-2.4	-1.1	-5.8	1	1	3	-41.5	66.3	-3.8	5	II	52.6	47	50.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1381	NM_053656	Huesken	P2rx2	22953	AAGGGGUAACCUCGAUCCUgg	AGGAUCGAGGUUACCCCUU	-2.1	-0.9	-1.9	1	2	4	-41	49	-0.9	3	II	52.6	50.9	76.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1382	NM_053656	Huesken	P2rx2	22953	UCGAUCCUGGUGAUGAUGCug	GCAUCAUCACCAGGAUCGA	-3.4	-2.4	0.8	1	3	2	-40.4	67.4	7.1	6	II	52.6	66.1	78.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1383	NM_053656	Huesken	P2rx2	22953	GAUGAUGCUGACUACACUGcc	CAGUGUAGUCAGCAUCAUC	-2.1	-2.4	-0.8	0	2	2	-37.5	62.3	2.7	4	II	47.4	55.5	78.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1384	NM_053656	Huesken	P2rx2	22953	GGGGCUUUACGUAUUCCUCca	GAGGAAUACGUAAAGCCCC	-2.4	-3.3	0.9	1	1	5	-38.8	66	10.2	1	II	52.6	46.4	34.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1385	NM_053656	Huesken	P2rx2	22953	GUCCCACACUUUGUCUUCCga	GGAAGACAAAGUGUGGGAC	-3.3	-2.2	1	2	2	3	-39.1	59.9	12.8	2	II	52.6	46.2	69.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1386	NM_053656	Huesken	P2rx2	22953	UCCCACACUUUGUCUUCCGac	CGGAAGACAAAGUGUGGGA	-2.4	-2.4	1	1	3	3	-39.3	63	2.7	5	II	52.6	62.8	64.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1387	NM_053656	Huesken	P2rx2	22953	UGGUGAUCCCCUUGACUUUgg	AAAGUCAAGGGGAUCACCA	-0.9	-2.1	-2.2	1	-1	4	-39.1	65.1	-3.3	5	II	47.4	50.8	66.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1388	NM_053656	Huesken	P2rx2	22953	CUUGACUUUGGUGAUGAUGga	CAUCAUCACCAAAGUCAAG	-2.1	-2.1	2.5	0	0	2	-34.5	69.7	3.7	4	II	42.1	54.6	71.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1389	NM_053656	Huesken	P2rx2	22953	UGAUGAUGGAGCUCUCCGGuc	CCGGAGAGCUCCAUCAUCA	-3.3	-2.1	-3.3	2	4	4	-42.5	62.7	-2.4	5	Ia	57.9	65.6	54.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1390	NM_053656	Huesken	P2rx2	22953	CCGGUCUCGCUGUCCUGGUag	ACCAGGACAGCGAGACCGG	-2.2	-3.3	0.1	1	-2	4	-45.7	40.2	-6	1	III	68.4	36.1	49.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1391	NM_053656	Huesken	P2rx2	22953	GUCUCGCUGUCCUGGUAGCuu	GCUACCAGGACAGCGAGAC	-3.4	-2.2	-1.9	0	1	3	-43.5	49.9	2.7	0	II	63.2	37.1	60.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1392	NM_053656	Huesken	P2rx2	22953	CUGGUAGCUUUUCUGCACGau	CGUGCAGAAAAGCUACCAG	-2.4	-2.1	-0.7	-1	1	2	-38	59.3	5.8	3	II	52.6	54.8	80.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1393	NM_053656	Huesken	P2rx2	22953	UGGUAGCUUUUCUGCACGAug	UCGUGCAGAAAAGCUACCA	-2.4	-2.1	-0.7	-1	0	2	-38.3	56.1	-3.4	5	II	47.4	48.7	74.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1394	NM_053656	Huesken	P2rx2	22953	UUCUGCACGAUGAAGACGUac	ACGUCUUCAUCGUGCAGAA	-2.2	-0.9	-0.4	1	2	2	-37.8	64.8	-6.6	7	II	47.4	68	85.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1395	NM_053656	Huesken	P2rx2	22953	GAAGUAAAGCAGGAUGAGAag	UCUCAUCCUGCUUUACUUC	-2.4	-2.4	3.3	1	-1	2	-36.2	48.8	-1.5	4	II	42.1	38.9	61.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1396	NM_053656	Huesken	P2rx2	22953	CAGGCGCCGAUUCCGCACCac	GGUGCGGAAUCGGCGCCUG	-3.3	-2.1	-7.5	0	0	7	-45.9	41.4	10.8	0	II	73.7	50.6	69.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1397	NM_003348	Huesken	UBE2N	7334	UAGCCUAGUCCAUGCUCUAgc	UAGAGCAUGGACUAGGCUA	-1.3	-1.3	-1.1	0	0	3	-40.1	59.2	-6.1	4	II	47.4	54.3	73.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1398	NM_003348	Huesken	UBE2N	7334	UCCAUGCUCUAGCUGUUUCua	GAAACAGCUAGAGCAUGGA	-2.4	-2.4	-1.4	1	2	2	-38.4	77.8	14.4	5	II	47.4	59.8	100.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1399	NM_003348	Huesken	UBE2N	7334	AUGCUCUAGCUGUUUCUAUgg	AUAGAAACAGCUAGAGCAU	-1.1	-1.1	-1.4	4	1	2	-35.1	78	-1.6	5	II	36.8	54.8	91.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1400	NM_003348	Huesken	UBE2N	7334	UGCUCUAGCUGUUUCUAUGgc	CAUAGAAACAGCUAGAGCA	-2.1	-2.1	-1.4	1	2	2	-36.1	90	5.4	4	Ib	42.1	63.6	95.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1401	NM_003348	Huesken	UBE2N	7334	CUAGCUGUUUCUAUGGCUUgg	AAGCCAUAGAAACAGCUAG	-0.9	-2.1	-0.5	-1	0	3	-35.8	67.6	-5.6	3	III	42.1	49.3	90.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1402	NM_003348	Huesken	UBE2N	7334	GCUGUUUCUAUGGCUUGGGcu	CCCAAGCCAUAGAAACAGC	-3.3	-3.4	1.9	1	2	3	-39	58.8	0	4	II	52.6	48.5	60.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1403	NM_003348	Huesken	UBE2N	7334	UGUUUCUAUGGCUUGGGCUuc	AGCCCAAGCCAUAGAAACA	-2.1	-2.1	0.2	1	3	4	-39	82.5	-4	7	II	47.4	63.3	91.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1404	NM_003348	Huesken	UBE2N	7334	GUUUCUAUGGCUUGGGCUUcg	AAGCCCAAGCCAUAGAAAC	-0.9	-2.2	0.2	0	0	4	-37.8	68.4	-3.3	4	II	47.4	42	61.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1405	NM_003348	Huesken	UBE2N	7334	UUUCUAUGGCUUGGGCUUCgu	GAAGCCCAAGCCAUAGAAA	-2.4	-0.9	0.2	2	3	4	-38	66.6	10.4	8	Ia	47.4	66.9	90.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1406	NM_003348	Huesken	UBE2N	7334	UUCUAUGGCUUGGGCUUCGuu	CGAAGCCCAAGCCAUAGAA	-2.4	-0.9	0.2	0	3	4	-39.5	61.8	2.7	8	Ia	52.6	66.8	84.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1407	NM_003348	Huesken	UBE2N	7334	UCUAUGGCUUGGGCUUCGUug	ACGAAGCCCAAGCCAUAGA	-2.2	-2.4	0.2	0	2	4	-40.8	58.8	-4	7	II	52.6	53.5	77.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1408	NM_003348	Huesken	UBE2N	7334	UAUGGCUUGGGCUUCGUUGgu	CAACGAAGCCCAAGCCAUA	-2.1	-1.3	0.2	2	4	4	-39.3	77.3	0	7	Ib	52.6	71.1	94	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1409	NM_003348	Huesken	UBE2N	7334	UUGGGCUUCGUUGGUCUUCca	GAAGACCAACGAAGCCCAA	-2.4	-0.9		1	2	4	-39.3	64.1	10.4	6	II	52.6	68.5	85.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1410	NM_003348	Huesken	UBE2N	7334	CUUCGUUGGUCUUCCACUGcu	CAGUGGAAGACCAACGAAG	-2.1	-2.1	-1.4	2	1	2	-38.1	63.6	-1.3	2	II	52.6	53.6	78	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1411	NM_003348	Huesken	UBE2N	7334	GGUCUUCCACUGCUCCGCUac	AGCGGAGCAGUGGAAGACC	-2.1	-3.3	0.2	1	1	4	-44.2	46.7	0.8	1	III	63.2	35.3	43.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1412	NM_003348	Huesken	UBE2N	7334	GUCUUCCACUGCUCCGCUAca	UAGCGGAGCAGUGGAAGAC	-1.3	-2.2	0.2	1	-2	4	-42.2	54.5	-6.1	2	III	57.9	30.4	40.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1413	NM_003348	Huesken	UBE2N	7334	CUGCUCCGCUACAUCAUUUgc	AAAUGAUGUAGCGGAGCAG	-0.9	-2.1	-0.3	1	-2	4	-37.4	61.8	-6.3	3	III	47.4	43.4	43.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1414	NM_003348	Huesken	UBE2N	7334	UGCUCCGCUACAUCAUUUGcu	CAAAUGAUGUAGCGGAGCA	-2.1	-2.1	0.4	0	1	4	-37.4	75.3	-2.4	7	II	47.4	61.3	64.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1415	NM_003348	Huesken	UBE2N	7334	GCUCCGCUACAUCAUUUGCua	GCAAAUGAUGUAGCGGAGC	-3.4	-3.4	-0.1	1	1	4	-38.7	61.4	15.1	2	II	52.6	39	49.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1416	NM_003348	Huesken	UBE2N	7334	CGCUACAUCAUUUGCUAAUgg	AUUAGCAAAUGAUGUAGCG	-1.1	-2.4	-0.3	-1	-4	3	-32.9	72.4	-0.3	4	III	36.8	37.7	34.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1417	NM_003348	Huesken	UBE2N	7334	GCUACAUCAUUUGCUAAUGga	CAUUAGCAAAUGAUGUAGC	-2.1	-3.4	-1.6	1	0	2	-32.6	70.6	3	2	II	36.8	43.7	30.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1418	NM_003348	Huesken	UBE2N	7334	CUACAUCAUUUGCUAAUGGau	CCAUUAGCAAAUGAUGUAG	-3.3	-2.1	-1.9	0	2	2	-32.5	67.9	5.4	3	II	36.8	55.3	77.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1419	NM_003348	Huesken	UBE2N	7334	CAUCAUUUGCUAAUGGAUCau	GAUCCAUUAGCAAAUGAUG	-2.4	-2.1	-1.3	2	1	2	-32.8	73.4	7.8	3	II	36.8	59.9	61.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1420	NM_003348	Huesken	UBE2N	7334	AUCAUUUGCUAAUGGAUCAuc	UGAUCCAUUAGCAAAUGAU	-2.1	-1.1	-0.4	2	0	2	-32.8	84.2	-1.5	7	II	31.6	59	70.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1421	NM_003348	Huesken	UBE2N	7334	UGCUAAUGGAUCAUCUGGAuu	UCCAGAUGAUCCAUUAGCA	-2.4	-2.1	0.7	2	1	2	-37.7	67	-3.7	7	II	42.1	56.3	85.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1422	NM_003348	Huesken	UBE2N	7334	UGGAUCAUCUGGAUUGGGAgc	UCCCAAUCCAGAUGAUCCA	-2.4	-2.1	1.4	1	1	3	-39.9	69.5	-4	6	II	47.4	53.9	78.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1423	NM_003348	Huesken	UBE2N	7334	GGAUCAUCUGGAUUGGGAGca	CUCCCAAUCCAGAUGAUCC	-2.1	-3.3	1.4	1	2	3	-39.9	61.5	2.3	3	II	52.6	39.9	58.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1424	NM_003348	Huesken	UBE2N	7334	GAUAGCAGAACUGUGCGGAuc	UCCGCACAGUUCUGCUAUC	-2.4	-2.4	-1.8	0	1	4	-40	55.3	-0.8	4	II	52.6	39.6	63.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1425	NM_003348	Huesken	UBE2N	7334	AUAGCAGAACUGUGCGGAUcu	AUCCGCACAGUUCUGCUAU	-1.1	-1.1	-1.8	0	2	4	-38.7	48.9	-4	4	II	47.4	45.3	54.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1426	NM_003348	Huesken	UBE2N	7334	CAGAACUGUGCGGAUCUGCag	GCAGAUCCGCACAGUUCUG	-3.4	-2.1	-1.4	0	0	4	-40.8	51.3	5.8	3	II	57.9	53.4	86.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1427	NM_003348	Huesken	UBE2N	7334	AUCUGCAGUGCUGGGGACCac	GGUCCCCAGCACUGCAGAU	-3.3	-1.1	0.4	0	3	4	-45	48.9	8.1	4	Ib	63.2	57.1	62.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1428	NM_003348	Huesken	UBE2N	7334	CUGCAGUGCUGGGGACCACuu	GUGGUCCCCAGCACUGCAG	-2.2	-2.1	-2.4	1	0	4	-45.8	28.5	8.1	1	II	68.4	38.6	59.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1429	NM_003348	Huesken	UBE2N	7334	GCAGUGCUGGGGACCACUUau	AAGUGGUCCCCAGCACUGC	-0.9	-3.4	-2.7	1	-1	4	-44.6	33.2	-6.6	0	III	63.2	33.1	48.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1430	NM_003348	Huesken	UBE2N	7334	GGGGACCACUUAUCUUUCAaa	UGAAAGAUAAGUGGUCCCC	-2.1	-3.3	0.2	1	-3	4	-38.3	50.6	-1.1	2	III	47.4	30.6	34.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1431	NM_003348	Huesken	UBE2N	7334	GACCACUUAUCUUUCAAAAua	UUUUGAAAGAUAAGUGGUC	-0.9	-2.4	1	2	-2	2	-31.1	79	2	3	III	31.6	36.1	35.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1432	NM_003348	Huesken	UBE2N	7334	CUUAUCUUUCAAAAUAUCUag	AGAUAUUUUGAAAGAUAAG	-2.1	-2.1	0.4	0	-1	1	-26.9	93.9	-6.3	6	II	21.1	62.7	57.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1433	NM_003348	Huesken	UBE2N	7334	UUAUCUUUCAAAAUAUCUAga	UAGAUAUUUUGAAAGAUAA	-1.3	-0.9	0.4	2	2	1	-26.1	105.8	-1.7	8	II	15.8	75.2	80.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1434	NM_003348	Huesken	UBE2N	7334	UAUCUUUCAAAAUAUCUAGac	CUAGAUAUUUUGAAAGAUA	-2.1	-1.3	1.2	2	3	1	-27.3	105.7	2.3	9	Ia	21.1	78.9	85.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1435	NM_003348	Huesken	UBE2N	7334	UUUCAAAAUAUCUAGACAUau	AUGUCUAGAUAUUUUGAAA	-1.1	-0.9	1.3	1	2	1	-28.2	85.2	-3.6	8	II	21.1	70.6	75.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1436	NM_003348	Huesken	UBE2N	7334	CUAGACAUAUUCUUCCCAAcu	UUGGGAAGAAUAUGUCUAG	-0.9	-2.1	-1.2	-1	-1	3	-34	66.1	-3.1	3	II	36.8	45.1	52.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1437	NM_003348	Huesken	UBE2N	7334	UUCUUCCCAACUUGUCUACau	GUAGACAAGUUGGGAAGAA	-2.2	-0.9	2	-1	2	3	-35.8	86.6	8.1	8	Ib	42.1	62.4	94	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1438	NM_003348	Huesken	UBE2N	7334	UUCCCAACUUGUCUACAUUag	AAUGUAGACAAGUUGGGAA	-0.9	-0.9	1	1	1	3	-34.5	78.5	3.8	5	II	36.8	58.3	93.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1439	NM_003348	Huesken	UBE2N	7334	CCAACUUGUCUACAUUAGGau	CCUAAUGUAGACAAGUUGG	-3.3	-3.3	-0.9	0	0	2	-34.6	65	0.4	3	II	42.1	53.2	69.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1440	NM_003348	Huesken	UBE2N	7334	UUGUCUACAUUAGGAUGAUaa	AUCAUCCUAAUGUAGACAA	-1.1	-0.9	1	-1	1	2	-33.1	71.2	-4	6	II	31.6	55.2	46.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1441	NM_003348	Huesken	UBE2N	7334	CUACAUUAGGAUGAUAAAUuu	AUUUAUCAUCCUAAUGUAG	-1.1	-2.1	1.5	2	-2	2	-29.7	73.6	2.1	4	II	26.3	50.3	49.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1442	NM_003348	Huesken	UBE2N	7334	UAGGAUGAUAAAUUUUGGUca	ACCAAAAUUUAUCAUCCUA	-2.2	-1.3	4.1	0	3	2	-30.3	88.2	3.4	7	II	26.3	70.5	81.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1443	NM_003348	Huesken	UBE2N	7334	AAAUUUUGGUCAUGAAACGua	CGUUUCAUGACCAAAAUUU	-2.4	-0.9	0.2	2	4	2	-29.7	80.2	-2.4	7	Ia	31.6	68.8	100	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1444	NM_003348	Huesken	UBE2N	7334	AAUUUUGGUCAUGAAACGUac	ACGUUUCAUGACCAAAAUU	-2.2	-0.9	0.2	1	3	2	-31	79.4	1.4	7	II	31.6	61	92.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1445	NM_003348	Huesken	UBE2N	7334	GUCAUGAAACGUACUUUAGgg	CUAAAGUACGUUUCAUGAC	-2.1	-2.2	1	0	0	2	-31.7	76	0.4	5	II	36.8	48	79.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1446	NM_003348	Huesken	UBE2N	7334	UUAGGGGCUGCCAUUGGGUau	ACCCAAUGGCAGCCCCUAA	-2.2	-0.9	0.4	0	4	5	-43.5	48.9	-8.9	5	II	57.9	63.4	64	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1447	NM_003348	Huesken	UBE2N	7334	GGCUGCCAUUGGGUAUUCUuc	AGAAUACCCAAUGGCAGCC	-2.1	-3.3	0.6	0	-1	3	-40.4	50.9	-1.6	2	III	52.6	27.3	44.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1448	NM_003348	Huesken	UBE2N	7334	GGGUAUUCUUCUGGAAGGAau	UCCUUCCAGAAGAAUACCC	-2.4	-3.3	0	0	-2	3	-38.5	49.2	-0.4	3	II	47.4	28.6	36.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1449	NM_003348	Huesken	UBE2N	7334	UAUUCUUCUGGAAGGAAUAgu	UAUUCCUUCCAGAAGAAUA	-1.3	-1.3	0	0	0	2	-33	82.6	-6.3	7	II	31.6	62.2	83	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1450	NM_003348	Huesken	UBE2N	7334	CUUCUGGAAGGAAUAGUUCaa	GAACUAUUCCUUCCAGAAG	-2.4	-2.1	0.5	0	1	2	-34.9	63.4	5.1	5	II	42.1	55.3	87.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1451	NM_003348	Huesken	UBE2N	7334	CUGGAAGGAAUAGUUCAAGuu	CUUGAACUAUUCCUUCCAG	-2.1	-2.1	1.6	-1	0	2	-34.6	52.3	3	4	II	42.1	48.8	84.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1452	NM_003348	Huesken	UBE2N	7334	UGGAAGGAAUAGUUCAAGUuu	ACUUGAACUAUUCCUUCCA	-2.2	-2.1	1.6	0	1	2	-34.7	73.4	3.4	6	II	36.8	59.8	96.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1453	NM_003348	Huesken	UBE2N	7334	GAAGGAAUAGUUCAAGUUUaa	AAACUUGAACUAUUCCUUC	-0.9	-2.4	2.1	0	-1	2	-31.1	63.6	1.5	4	II	31.6	46.1	43.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1454	NM_003348	Huesken	UBE2N	7334	GGAAUAGUUCAAGUUUAAAag	UUUAAACUUGAACUAUUCC	-0.9	-3.3	2.1	0	-2	2	-28.8	69.2	0.9	4	II	26.3	32.8	29.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1455	NM_003348	Huesken	UBE2N	7334	AGUUCAAGUUUAAAAGUCCcu	GGACUUUUAAACUUGAACU	-3.3	-2.1	1.9	1	3	2	-30.7	72.7	4.8	6	Ia	31.6	64.2	87.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1456	NM_003348	Huesken	UBE2N	7334	AAAAGUCCCUCCCUCAAAGgg	CUUUGAGGGAGGGACUUUU	-2.1	-0.9	-0.8	2	4	3	-37.6	67.9	0	5	Ia	47.4	59.2	70.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1457	NM_003348	Huesken	UBE2N	7334	GAAUCCUGAGGGCCAGCAAug	UUGCUGGCCCUCAGGAUUC	-0.9	-2.4	-1.3	1	-1	5	-42.7	50.3	-1.4	2	II	57.9	30.5	50.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1458	NM_003348	Huesken	UBE2N	7334	GAGGGCCAGCAAUGACCACau	GUGGUCAUUGCUGGCCCUC	-2.2	-2.4	-4.9	0	1	5	-43.8	32.3	9.7	-1	II	63.2	33.1	54.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1459	NM_003348	Huesken	UBE2N	7334	GGGCCAGCAAUGACCACAUga	AUGUGGUCAUUGCUGGCCC	-1.1	-3.3	-4.9	1	-2	5	-42.5	37.7	-6.6	0	III	57.9	31.3	47.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1460	NM_003348	Huesken	UBE2N	7334	GCCAGCAAUGACCACAUGAaa	UCAUGUGGUCAUUGCUGGC	-2.4	-3.4	-0.8	0	-3	3	-40.4	47.3	-1.4	3	III	52.6	34.3	50.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1461	NM_003348	Huesken	UBE2N	7334	CCAGCAAUGACCACAUGAAaa	UUCAUGUGGUCAUUGCUGG	-0.9	-3.3	0.6	0	-3	2	-37.9	44.5	-13	3	III	47.4	32	39.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1462	NM_003348	Huesken	UBE2N	7334	CAGCAAUGACCACAUGAAAau	UUUCAUGUGGUCAUUGCUG	-0.9	-2.1	0.6	1	-4	2	-35.5	48.5	-3	3	II	42.1	32.7	39.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1463	NM_003348	Huesken	UBE2N	7334	GCAAUGACCACAUGAAAAUaa	AUUUUCAUGUGGUCAUUGC	-1.1	-3.4	1	0	-2	2	-33.3	58.5	-6.3	5	II	36.8	39.2	47.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1464	NM_003348	Huesken	UBE2N	7334	ACAUGAAAAUAACGGGCGUug	ACGCCCGUUAUUUUCAUGU	-2.2	-2.2	1.8	0	2	6	-35.1	51.1	0.7	5	II	42.1	44.2	62.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1465	NM_003348	Huesken	UBE2N	7334	AUGAAAAUAACGGGCGUUGcu	CAACGCCCGUUAUUUUCAU	-2.1	-1.1	0	0	2	6	-33.8	62.3	0.4	8	Ia	42.1	61	87.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1466	NM_003348	Huesken	UBE2N	7334	GGGCGUUGCUCUCAUCUGGuu	CCAGAUGAGAGCAACGCCC	-3.3	-3.3	1.3	3	0	5	-43.1	47.7	3.1	1	II	63.2	41	65.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1467	NM_003348	Huesken	UBE2N	7334	UGCUCUCAUCUGGUUCGGCuu	GCCGAACCAGAUGAGAGCA	-3.4	-2.1	0.8	0	4	4	-42.2	61	9.7	3	II	57.9	57.6	82.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1468	NM_003348	Huesken	UBE2N	7334	CUCUCAUCUGGUUCGGCUUug	AAGCCGAACCAGAUGAGAG	-0.9	-2.1	3.3	0	-2	4	-39.7	67.7	-3	3	II	52.6	42.4	88.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1469	NM_003348	Huesken	UBE2N	7334	AUCUGGUUCGGCUUUGAUGcc	CAUCAAAGCCGAACCAGAU	-2.1	-1.1	0.9	3	3	4	-37.2	78	0	5	Ib	47.4	62.9	84.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1470	NM_003348	Huesken	UBE2N	7334	UGGUUCGGCUUUGAUGCCAgg	UGGCAUCAAAGCCGAACCA	-2.1	-2.1	-4.5	1	0	4	-40.4	57.4	-0.7	5	II	52.6	53	81.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1471	NM_003348	Huesken	UBE2N	7334	CGGCUUUGAUGCCAGGAACug	GUUCCUGGCAUCAAAGCCG	-2.2	-2.4	-4.5	1	-2	4	-40.4	52.2	5.5	0	II	57.9	40.4	78.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1472	NM_003348	Huesken	UBE2N	7334	GCUUUGAUGCCAGGAACUGgu	CAGUUCCUGGCAUCAAAGC	-2.1	-3.4	0.2	0	1	3	-38.9	42.8	-2.4	4	II	52.6	38.6	61.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1473	NM_003348	Huesken	UBE2N	7334	UUUGAUGCCAGGAACUGGUuc	ACCAGUUCCUGGCAUCAAA	-2.2	-0.9	-2.7	1	3	3	-38.9	67.3	-3.9	7	II	47.4	69.2	97.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1474	NM_003348	Huesken	UBE2N	7334	UGAUGCCAGGAACUGGUUCug	GAACCAGUUCCUGGCAUCA	-2.4	-2.1	-2.7	1	3	3	-40.4	64.4	14.4	5	II	52.6	60.4	36	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1475	NM_003348	Huesken	UBE2N	7334	GAUGCCAGGAACUGGUUCUgc	AGAACCAGUUCCUGGCAUC	-2.1	-2.4	-2.7	0	0	3	-40.4	61.1	-4	4	III	52.6	43.9	60.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1476	NM_003342	Huesken	UBE2G1	7326	UUUUCUUACACAGCGGGCAac	UGCCCGCUGUGUAAGAAAA	-2.1	-0.9	0.8	2	2	6	-38	74.7	-6.1	8	II	47.4	66.8	94.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1477	NM_003342	Huesken	UBE2G1	7326	CUUACACAGCGGGCAACUUuu	AAGUUGCCCGCUGUGUAAG	-0.9	-2.1	0.2	0	-1	6	-39	47.2	-6	3	II	52.6	36.2	79	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1478	NM_003342	Huesken	UBE2G1	7326	UUACACAGCGGGCAACUUUuc	AAAGUUGCCCGCUGUGUAA	-0.9	-0.9	0.4	2	1	6	-37.8	61	1.1	8	II	47.4	63.3	93.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1479	NM_003342	Huesken	UBE2G1	7326	GGGCAACUUUUCUUUUAAAuu	UUUAAAAGAAAAGUUGCCC	-0.9	-3.3	2.6	1	-3	4	-30.3	63	-1.1	1	III	31.6	24.5	43.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1480	NM_003342	Huesken	UBE2G1	7326	ACUUUUCUUUUAAAUUCUCca	GAGAAUUUAAAAGAAAAGU	-2.4	-2.2	2.3	1	3	1	-26.2	87.1	4.8	5	Ia	21.1	62.6	56.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1481	NM_003342	Huesken	UBE2G1	7326	UUUUCUUUUAAAUUCUCCAuu	UGGAGAAUUUAAAAGAAAA	-2.1	-0.9	2.3	1	3	2	-27.3	113.4	0.9	8	II	21.1	78.6	74.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1482	NM_003342	Huesken	UBE2G1	7326	AAAUUCUCCAUUUCUAUCUuc	AGAUAGAAAUGGAGAAUUU	-2.1	-0.9	0.9	3	2	2	-30.4	103.9	-1	9	II	26.3	73.7	102	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1483	NM_003342	Huesken	UBE2G1	7326	UUUCUAUCUUCCCUCCAUUcu	AAUGGAGGGAAGAUAGAAA	-0.9	-0.9	3.9	2	2	3	-35	81.4	-3.9	7	II	36.8	65.4	85.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1484	NM_003342	Huesken	UBE2G1	7326	UUCCCUCCAUUCUUUCGCAgc	UGCGAAAGAAUGGAGGGAA	-2.1	-0.9	2.7	1	2	3	-38.4	71.6	-3.8	4	II	47.4	56.5	72.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1485	NM_003342	Huesken	UBE2G1	7326	CCCUCCAUUCUUUCGCAGCau	GCUGCGAAAGAAUGGAGGG	-3.4	-3.3	0.8	-1	-1	3	-40.6	63.4	8.4	1	II	57.9	46.4	63.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1486	NM_003342	Huesken	UBE2G1	7326	CCUCCAUUCUUUCGCAGCAuc	UGCUGCGAAAGAAUGGAGG	-2.1	-3.3	0.8	1	-2	3	-39.4	51.1	-0.3	2	III	52.6	34.1	34.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1487	NM_003342	Huesken	UBE2G1	7326	UCUUUCGCAGCAUCAACAUua	AUGUUGAUGCUGCGAAAGA	-1.1	-2.4	0.6	0	1	3	-36.1	70.4	-6.3	7	II	42.1	53.7	104.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1488	NM_003342	Huesken	UBE2G1	7326	CUUUCGCAGCAUCAACAUUag	AAUGUUGAUGCUGCGAAAG	-0.9	-2.1	0.6	0	-2	3	-34.6	64	1.8	3	III	42.1	40.8	93.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1489	NM_003342	Huesken	UBE2G1	7326	CAGCAUCAACAUUAGCAGGug	CCUGCUAAUGUUGAUGCUG	-3.3	-2.1	-0.1	0	0	2	-36.8	62.3	6	2	II	47.4	49.7	97.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1490	NM_003342	Huesken	UBE2G1	7326	AGCAUCAACAUUAGCAGGUga	ACCUGCUAAUGUUGAUGCU	-2.2	-2.1	-0.1	1	1	2	-36.9	64.8	-3.5	6	II	42.1	54.4	93.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1491	NM_003342	Huesken	UBE2G1	7326	AACAUUAGCAGGUGAGUCUcc	AGACUCACCUGCUAAUGUU	-2.1	-0.9	1.3	1	1	2	-37	75.3	-4	8	II	42.1	60.1	81.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1492	NM_003342	Huesken	UBE2G1	7326	GCAGGUGAGUCUCCAUUAGgg	CUAAUGGAGACUCACCUGC	-2.1	-3.4	0.3	1	0	2	-39.6	46.8	3.1	3	II	52.6	35.3	71.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1493	NM_003342	Huesken	UBE2G1	7326	UGAGUCUCCAUUAGGGUCUgc	AGACCCUAAUGGAGACUCA	-2.1	-2.1	-1.1	1	1	3	-39.8	70.2	-3.5	7	II	47.4	66.6	89.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1494	NM_003342	Huesken	UBE2G1	7326	AGGGUCUGCCAGCAUAGAAau	UUCUAUGCUGGCAGACCCU	-0.9	-2.1	0.4	3	-1	3	-41.7	53.1	1	4	II	52.6	39.6	61	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1495	NM_003342	Huesken	UBE2G1	7326	CCAGCAUAGAAAUGACACUaa	AGUGUCAUUUCUAUGCUGG	-2.1	-3.3	0	0	-2	2	-35.9	53.3	-3.7	3	III	42.1	43.1	47.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1496	NM_003342	Huesken	UBE2G1	7326	AGCAUAGAAAUGACACUAAuc	UUAGUGUCAUUUCUAUGCU	-0.9	-2.1	0.4	1	-2	2	-32.7	64.2	-6.3	7	II	31.6	44.3	54	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1497	NM_003342	Huesken	UBE2G1	7326	AUAGAAAUGACACUAAUCAug	UGAUUAGUGUCAUUUCUAU	-2.1	-1.1	-1.2	2	2	1	-30.7	75.7	1.3	7	II	26.3	64.6	78.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1498	NM_003342	Huesken	UBE2G1	7326	GACACUAAUCAUGAUGGUUuc	AACCAUCAUGAUUAGUGUC	-0.9	-2.4	0.6	0	-1	2	-34	69.5	1.4	3	II	36.8	42.2	65.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1499	NM_003342	Huesken	UBE2G1	7326	ACACUAAUCAUGAUGGUUUcc	AAACCAUCAUGAUUAGUGU	-0.9	-2.2	0.6	3	1	2	-32.5	74.1	-4.2	7	II	31.6	58.5	66.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1500	NM_003342	Huesken	UBE2G1	7326	ACUAAUCAUGAUGGUUUCCac	GGAAACCAUCAUGAUUAGU	-3.3	-2.2	0.7	0	3	2	-33.9	74.1	15.4	6	Ia	36.8	58.2	54.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1501	NM_003342	Huesken	UBE2G1	7326	AUGAUGGUUUCCACAGUGUgg	ACACUGUGGAAACCAUCAU	-2.2	-1.1	-0.9	1	1	2	-36.8	64.9	-11.3	7	II	42.1	57.9	89.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1502	NM_003342	Huesken	UBE2G1	7326	GAUGGUUUCCACAGUGUGGau	CCACACUGUGGAAACCAUC	-3.3	-2.4	-3	1	2	2	-39	60.6	-2.6	3	II	52.6	50.5	86.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1503	NM_003342	Huesken	UBE2G1	7326	AUGGUUUCCACAGUGUGGAua	UCCACACUGUGGAAACCAU	-2.4	-1.1	-4.6	3	2	2	-39	65.9	-3.8	5	II	47.4	57.8	85.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1504	NM_003342	Huesken	UBE2G1	7326	GGUUUCCACAGUGUGGAUAgg	UAUCCACACUGUGGAAACC	-1.3	-3.3	-4.9	1	-2	2	-38.2	64.8	1.6	3	III	47.4	30.2	41.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1505	NM_003342	Huesken	UBE2G1	7326	UCCACAGUGUGGAUAGGGAgc	UCCCUAUCCACACUGUGGA	-2.4	-2.4	-4.1	1	1	3	-42	53	-4	4	II	52.6	44.1	62.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1506	NM_003342	Huesken	UBE2G1	7326	CCACAGUGUGGAUAGGGAGcc	CUCCCUAUCCACACUGUGG	-2.1	-3.3	-2	1	0	3	-41.7	40.3	0.7	1	II	57.9	41.5	62.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1507	NM_003342	Huesken	UBE2G1	7326	GUGUGGAUAGGGAGCCAGCgu	GCUGGCUCCCUAUCCACAC	-3.4	-2.2	-0.4	-1	1	3	-44.2	41.4	4.8	2	II	63.2	47.1	64	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1508	NM_003342	Huesken	UBE2G1	7326	GGGAGCCAGCGUUCCUCUGgc	CAGAGGAACGCUGGCUCCC	-2.1	-3.3	-1.6	1	0	3	-45.3	42.5	3	-1	II	68.4	33.2	42.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1509	NM_003342	Huesken	UBE2G1	7326	AGCCAGCGUUCCUCUGGCUuu	AGCCAGAGGAACGCUGGCU	-2.1	-2.1	-7.9	2	1	3	-45.1	39.5	-6	1	II	63.2	38.6	37.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1510	NM_003342	Huesken	UBE2G1	7326	GCCAGCGUUCCUCUGGCUUuu	AAGCCAGAGGAACGCUGGC	-0.9	-3.4	-6.5	0	-1	3	-43.9	45.4	1.4	0	III	63.2	29	35.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1511	NM_003342	Huesken	UBE2G1	7326	CAGCGUUCCUCUGGCUUUUca	AAAAGCCAGAGGAACGCUG	-0.9	-2.1	-0.5	1	-3	3	-39	52.2	-5.3	3	III	52.6	38.9	32.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1512	NM_003342	Huesken	UBE2G1	7326	GCGUUCCUCUGGCUUUUCAua	UGAAAAGCCAGAGGAACGC	-2.1	-3.4	1.1	1	-2	3	-39.3	63	1	3	III	52.6	28.5	35.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1513	NM_003342	Huesken	UBE2G1	7326	UCCUCUGGCUUUUCAUAACca	GUUAUGAAAAGCCAGAGGA	-2.2	-2.4	1	1	1	3	-35.9	79.5	10.4	5	II	42.1	58.3	49.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1514	NM_003342	Huesken	UBE2G1	7326	UCUGGCUUUUCAUAACCAUac	AUGGUUAUGAAAAGCCAGA	-1.1	-2.4	-4.2	1	1	3	-34.6	68.1	-6.3	4	II	36.8	54.6	39.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1515	NM_003342	Huesken	UBE2G1	7326	CUGGCUUUUCAUAACCAUAcu	UAUGGUUAUGAAAAGCCAG	-1.3	-2.1	-4.2	0	-4	3	-33.5	71.7	-3	1	III	36.8	49	31.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1516	NM_003342	Huesken	UBE2G1	7326	UUUUCAUAACCAUACUUAUcu	AUAAGUAUGGUUAUGAAAA	-1.1	-0.9	1.3	1	1	2	-28.1	96.3	-6.3	8	II	21.1	64.5	69.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1517	NM_003342	Huesken	UBE2G1	7326	UUUCAUAACCAUACUUAUCuu	GAUAAGUAUGGUUAUGAAA	-2.4	-0.9	1.3	2	3	2	-29.6	94.8	12.8	7	Ia	26.3	78.4	87.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1518	NM_003342	Huesken	UBE2G1	7326	CCAUACUUAUCUUCCCCAGgc	CUGGGGAAGAUAAGUAUGG	-2.1	-3.3	1	0	0	4	-37.3	68	1.4	4	II	47.4	45	55	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1519	NM_003342	Huesken	UBE2G1	7326	UACUUAUCUUCCCCAGGCUca	AGCCUGGGGAAGAUAAGUA	-2.1	-1.3	0.7	1	2	4	-39.6	71.3	-6.3	7	II	47.4	61	78.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1520	NM_003342	Huesken	UBE2G1	7326	UAUCUUCCCCAGGCUCAUGaa	CAUGAGCCUGGGGAAGAUA	-2.1	-1.3	0.7	2	3	4	-40.8	68.1	2.3	6	Ia	52.6	64.4	76	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1521	NM_003342	Huesken	UBE2G1	7326	AUCUUCCCCAGGCUCAUGAag	UCAUGAGCCUGGGGAAGAU	-2.4	-1.1	0.7	2	1	4	-41.9	72.1	1	7	II	52.6	51.2	76.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1522	NM_003342	Huesken	UBE2G1	7326	GGCUCAUGAAGAAUAGAAAug	UUUCUAUUCUUCAUGAGCC	-0.9	-3.3	0.3	1	-3	3	-33.9	63.3	-4	3	III	36.8	28.3	29.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1523	NM_003342	Huesken	UBE2G1	7326	AAUAGAAAUGCACACAUCAcc	UGAUGUGUGCAUUUCUAUU	-2.1	-0.9	-0.9	1	1	2	-32.5	69	-3.7	7	II	31.6	61.2	74.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1524	NM_003342	Huesken	UBE2G1	7326	UAGAAAUGCACACAUCACCau	GGUGAUGUGUGCAUUUCUA	-3.3	-1.3	-0.9	2	3	2	-36	74.5	10.2	8	Ia	42.1	79.3	94.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1525	NM_003342	Huesken	UBE2G1	7326	AGAAAUGCACACAUCACCAuu	UGGUGAUGUGUGCAUUUCU	-2.1	-2.1	-0.9	1	2	2	-36.8	64.9	-1.4	6	II	42.1	57.6	85	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1526	NM_003342	Huesken	UBE2G1	7326	UUUUAUCAACAUUUGGGUGcc	CACCCAAAUGUUGAUAAAA	-2.1	-0.9	1.8	0	5	3	-30.7	97.2	10.4	7	Ia	31.6	70.3	73.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1527	NM_003342	Huesken	UBE2G1	7326	UCAACAUUUGGGUGCCAGAuu	UCUGGCACCCAAAUGUUGA	-2.4	-2.4	-0.2	0	0	3	-38.9	63.3	-3.8	6	II	47.4	53.2	73.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1528	NM_003342	Huesken	UBE2G1	7326	AACAUUUGGGUGCCAGAUUuc	AAUCUGGCACCCAAAUGUU	-0.9	-0.9	-0.1	3	0	3	-36.4	68.3	-1.6	6	II	42.1	55.9	73.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1529	NM_003342	Huesken	UBE2G1	7326	GUGCCAGAUUUCUGUAAUGaa	CAUUACAGAAAUCUGGCAC	-2.1	-2.2	-2.5	0	0	3	-34.7	55.5	-2.4	1	II	42.1	43	50.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1530	NM_003342	Huesken	UBE2G1	7326	AUUUCUGUAAUGAAUUUCAuu	UGAAAUUCAUUACAGAAAU	-2.1	-1.1	0	1	1	1	-27.8	94.6	-6.3	8	II	21.1	66.1	61.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1531	NM_003342	Huesken	UBE2G1	7326	UAAUGAAUUUCAUUUUAGGag	CCUAAAAUGAAAUUCAUUA	-3.3	-1.3	-1.1	0	5	2	-26.6	96.4	0	6	Ia	21.1	75.7	69.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1532	NM_003342	Huesken	UBE2G1	7326	AUGAAUUUCAUUUUAGGAGgu	CUCCUAAAAUGAAAUUCAU	-2.1	-1.1	0.5	3	4	2	-28.9	98.1	8.1	7	Ia	26.3	71.9	87.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1533	NM_003342	Huesken	UBE2G1	7326	GAAUUUCAUUUUAGGAGGUcg	ACCUCCUAAAAUGAAAUUC	-2.2	-2.4	2.3	-1	1	2	-31.2	69.3	-3.5	4	II	31.6	43.8	39.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1534	NM_003342	Huesken	UBE2G1	7326	AUUUUAGGAGGUCGGAGGGga	CCCUCCGACCUCCUAAAAU	-3.3	-1.1		0	5	3	-39.7	62.4	5.4	7	Ia	52.6	56.3	62.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1535	NM_003342	Huesken	UBE2G1	7326	GAGGUCGGAGGGGAUAAUCuu	GAUUAUCCCCUCCGACCUC	-2.4	-2.4	1.8	0	0	4	-41.7	44.6	7.4	2	II	57.9	44.6	84.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1536	NM_003342	Huesken	UBE2G1	7326	AGGUCGGAGGGGAUAAUCUuu	AGAUUAUCCCCUCCGACCU	-2.1	-2.1	1.8	2	1	4	-41.4	54.8	-4.2	5	II	52.6	50.5	84.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1537	NM_003342	Huesken	UBE2G1	7326	CACCUUCAUAAAGUGUAUCug	GAUACACUUUAUGAAGGUG	-2.4	-2.1	-2.2	0	0	2	-32.7	73.5	10	2	II	36.8	53	66	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1538	NM_003342	Huesken	UBE2G1	7326	ACCUUCAUAAAGUGUAUCUgg	AGAUACACUUUAUGAAGGU	-2.1	-2.2	0.3	0	0	2	-32.7	86.2	-1.7	7	II	31.6	54.9	78.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1539	NM_003342	Huesken	UBE2G1	7326	UAAAGUGUAUCUGGAGGGCca	GCCCUCCAGAUACACUUUA	-3.4	-1.3	2.5	-1	5	4	-38.5	62.6	8.1	7	Ia	47.4	66.2	75.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1540	NM_003342	Huesken	UBE2G1	7326	GUGUAUCUGGAGGGCCAAUaa	AUUGGCCCUCCAGAUACAC	-1.1	-2.2	-1.5	0	-2	5	-40.7	45.7	1	2	II	52.6	30.8	36.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1541	NM_003342	Huesken	UBE2G1	7326	GGAGGGCCAAUAAUAAGGAcu	UCCUUAUUAUUGGCCCUCC	-2.4	-3.3	-0.2	0	0	5	-38.5	39.3	-4	2	III	47.4	34.9	44.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1542	NM_003342	Huesken	UBE2G1	7326	GGCCAAUAAUAAGGACUUCcc	GAAGUCCUUAUUAUUGGCC	-2.4	-3.3	-0.2	1	-1	4	-35	47.3	12.4	3	II	42.1	34.6	87.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1543	NM_003342	Huesken	UBE2G1	7326	GCCAAUAAUAAGGACUUCCca	GGAAGUCCUUAUUAUUGGC	-3.3	-3.4	-1	0	0	3	-35	66	12.4	4	II	42.1	54.6	71	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1544	NM_003342	Huesken	UBE2G1	7326	UAAGGACUUCCCAUCGGUAga	UACCGAUGGGAAGUCCUUA	-1.3	-1.3	-2	0	2	3	-39	54.8	-8.7	4	II	47.4	54.4	93.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1545	NM_003342	Huesken	UBE2G1	7326	GGACUUCCCAUCGGUAGAGau	CUCUACCGAUGGGAAGUCC	-2.1	-3.3	-0.9	1	1	3	-41.3	41.9	-2.4	2	II	57.9	36.5	68.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1546	NM_003342	Huesken	UBE2G1	7326	ACUUCCCAUCGGUAGAGAUca	AUCUCUACCGAUGGGAAGU	-1.1	-2.2	-2.7	1	1	3	-39.1	63.1	-4	3	II	47.4	38.7	67.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1547	NM_003342	Huesken	UBE2G1	7326	CCAUCGGUAGAGAUCAUUGuc	CAAUGAUCUCUACCGAUGG	-2.1	-3.3	-0.1	-1	0	3	-36.8	63.5	0	4	II	47.4	50.2	86.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1548	NM_003342	Huesken	UBE2G1	7326	AUCGGUAGAGAUCAUUGUCau	GACAAUGAUCUCUACCGAU	-2.4	-1.1	0.6	1	3	3	-36	70.8	15.1	4	Ib	42.1	62.5	103.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1549	NM_003342	Huesken	UBE2G1	7326	CGGUAGAGAUCAUUGUCAUcu	AUGACAAUGAUCUCUACCG	-1.1	-2.4	1.7	-1	-2	3	-35.7	58.5	-3.3	3	III	42.1	34.2	40.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1550	NM_003342	Huesken	UBE2G1	7326	UUGUCAUCUAUUAAACCUGca	CAGGUUUAAUAGAUGACAA	-2.1	-0.9	-0.4	1	3	2	-31.4	86	0.4	7	Ia	31.6	78.3	97.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1551	NM_003342	Huesken	UBE2G1	7326	CAUCUAUUAAACCUGCAGAaa	UCUGCAGGUUUAAUAGAUG	-2.4	-2.1	0.7	1	-1	2	-33.8	78	-1.1	5	II	36.8	48.4	60.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1552	NM_003342	Huesken	UBE2G1	7326	UCUAUUAAACCUGCAGAAAag	UUUCUGCAGGUUUAAUAGA	-0.9	-2.4	1.1	0	-1	2	-32.4	75.4	-3.1	7	II	31.6	51.9	51.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1553	NM_003342	Huesken	UBE2G1	7326	UUAAACCUGCAGAAAAGCCuu	GGCUUUUCUGCAGGUUUAA	-3.3	-0.9	-1.7	1	5	3	-35.2	71.1	9.8	6	Ia	42.1	75.9	83.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1554	NM_003342	Huesken	UBE2G1	7326	GAAAAGCCUUCCACUGGAUuu	AUCCAGUGGAAGGCUUUUC	-1.1	-2.4	-0.6	0	0	3	-37.9	48.5	-8.6	4	II	47.4	34.7	65.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1555	NM_006357	Huesken	UBE2E3	10477	CACUGUCUGGCUAUCCUGUcg	ACAGGAUAGCCAGACAGUG	-2.2	-2.1	-0.9	0	-1	3	-40.6	61.7	-5.6	3	III	52.6	43.4	55.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1556	NM_006357	Huesken	UBE2E3	10477	CUGUCUGGCUAUCCUGUCGug	CGACAGGAUAGCCAGACAG	-2.4	-2.1	-0.9	0	0	3	-41.1	68.1	5.7	3	II	57.9	52.8	78	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1557	NM_006357	Huesken	UBE2E3	10477	UGUCGUGUUCUGCUCUGUUgg	AACAGAGCAGAACACGACA	-0.9	-2.1		1	2	2	-38.3	65.3	0.8	5	II	47.4	55.9	76.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1558	NM_006357	Huesken	UBE2E3	10477	UCGUGUUCUGCUCUGUUGGuc	CCAACAGAGCAGAACACGA	-3.3	-2.4		1	3	2	-39.4	77.1	5.4	6	Ib	52.6	66.3	88.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1559	NM_006357	Huesken	UBE2E3	10477	GUUGGUCAAAUACUGAGUGgc	CACUCAGUAUUUGACCAAC	-2.1	-2.2	1	0	3	2	-34.6	64	4.7	3	II	42.1	51.8	87.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1560	NM_006357	Huesken	UBE2E3	10477	UGGUCAAAUACUGAGUGGCua	GCCACUCAGUAUUUGACCA	-3.4	-2.1	1	0	3	3	-38.2	68.4	8.1	6	Ib	47.4	65.2	90.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1561	NM_006357	Huesken	UBE2E3	10477	UCAAAUACUGAGUGGCUAUgc	AUAGCCACUCAGUAUUUGA	-1.1	-2.4	1.4	-1	0	3	-35.1	73	1	8	II	36.8	57.7	88.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1562	NM_006357	Huesken	UBE2E3	10477	GCUUCCAACCAGAGGAUCCgc	GGAUCCUCUGGUUGGAAGC	-3.3	-3.4	-2.4	0	1	2	-41.8	55.6	7.1	2	II	57.9	45.2	59.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1563	NM_006357	Huesken	UBE2E3	10477	UCCAACCAGAGGAUCCGCAgg	UGCGGAUCCUCUGGUUGGA	-2.1	-2.4	-1.6	1	1	4	-43.3	51.6	-1.3	4	II	57.9	50.8	75.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1564	NM_006357	Huesken	UBE2E3	10477	CAGAGGAUCCGCAGGGUUGca	CAACCCUGCGGAUCCUCUG	-2.1	-2.1	-0.2	-1	-1	4	-43	43.1	-6.9	3	II	63.2	46.9	56.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1565	NM_006357	Huesken	UBE2E3	10477	GGAUCCGCAGGGUUGCAGUcu	ACUGCAACCCUGCGGAUCC	-2.2	-3.3	-5.5	0	0	4	-44.1	51.8	-1.6	1	III	63.2	34	71.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1566	NM_006357	Huesken	UBE2E3	10477	GGGUUGCAGUCUGUCAAAAgg	UUUUGACAGACUGCAACCC	-0.9	-3.3	1.1	1	-3	3	-37.6	50.3	-0.8	2	III	47.4	23	50.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1567	NM_006357	Huesken	UBE2E3	10477	CUGUCAAAAGGGAACAAAUag	AUUUGUUCCCUUUUGACAG	-1.1	-2.1	-0.2	-1	-3	3	-32.8	62.8	-8.6	3	II	36.8	43.9	47.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1568	NM_006357	Huesken	UBE2E3	10477	UGUCAAAAGGGAACAAAUAga	UAUUUGUUCCCUUUUGACA	-1.3	-2.1	0.6	2	-1	3	-32	60.7	-3.6	6	II	31.6	53.5	45.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1569	NM_006357	Huesken	UBE2E3	10477	AAAAGGGAACAAAUAGACAgc	UGUCUAUUUGUUCCCUUUU	-2.1	-0.9	3.9	1	2	3	-32	64.4	-1.7	6	II	31.6	58.7	86	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1570	NM_006357	Huesken	UBE2E3	10477	AGGGAACAAAUAGACAGCAaa	UGCUGUCUAUUUGUUCCCU	-2.1	-2.1	2.1	1	0	3	-36.9	43.1	-1.1	4	II	42.1	46.8	73.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1571	NM_006357	Huesken	UBE2E3	10477	ACAAAUAGACAGCAAAACCuu	GGUUUUGCUGUCUAUUUGU	-3.3	-2.2	1.1	1	3	2	-33.1	69.6	14.8	6	Ia	36.8	67.2	94.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1572	NM_006357	Huesken	UBE2E3	10477	AUAGACAGCAAAACCUUUGaa	CAAAGGUUUUGCUGUCUAU	-2.1	-1.1	0.8	2	3	2	-33	73.2	2.4	8	Ia	36.8	71.8	92.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1573	NM_006357	Huesken	UBE2E3	10477	GCAAAACCUUUGAAAUAGUca	ACUAUUUCAAAGGUUUUGC	-2.2	-3.4	1.2	0	-1	2	-30.6	53.4	-3.9	3	II	31.6	36.7	34.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1574	NM_006357	Huesken	UBE2E3	10477	AAAUAGUCAAAGCGGGACUcc	AGUCCCGCUUUGACUAUUU	-2.1	-0.9	-1.8	1	2	5	-36	69.2	3.4	7	II	42.1	60.3	56.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1575	NM_006357	Huesken	UBE2E3	10477	AUAGUCAAAGCGGGACUCCag	GGAGUCCCGCUUUGACUAU	-3.3	-1.1	-2.2	0	4	5	-39.9	51.9	5.1	6	Ia	52.6	64.4	69.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1576	NM_006357	Huesken	UBE2E3	10477	AGUCAAAGCGGGACUCCAGuu	CUGGAGUCCCGCUUUGACU	-2.1	-2.1	-1.5	3	3	5	-41.7	45.4	0.1	3	Ia	57.9	49	72	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1577	NM_006357	Huesken	UBE2E3	10477	GGGACUCCAGUUGUCUUUAag	UAAAGACAACUGGAGUCCC	-1.3	-3.3	-1.2	0	-3	3	-38.2	59.6	1.6	1	III	47.4	30.8	43.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1578	NM_006357	Huesken	UBE2E3	10477	ACUCCAGUUGUCUUUAAGGau	CCUUAAAGACAACUGGAGU	-3.3	-2.2	0.3	2	4	2	-35.5	70.9	0	4	II	42.1	58.8	58.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1579	NM_006357	Huesken	UBE2E3	10477	GGAUGUCCAGACAGAUGACuc	GUCAUCUGUCUGGACAUCC	-2.2	-3.3	-1.3	-1	1	2	-40	46.1	4.8	1	II	52.6	33.9	43.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1580	NM_006357	Huesken	UBE2E3	10477	UGUCCAGACAGAUGACUCCcu	GGAGUCAUCUGUCUGGACA	-3.3	-2.1	-1.5	1	3	2	-41	61.8	7.4	6	II	52.6	64.1	75.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1581	NM_006357	Huesken	UBE2E3	10477	CAGACAGAUGACUCCCUGAcu	UCAGGGAGUCAUCUGUCUG	-2.4	-2.1	-1.9	-1	-3	3	-40.9	55.2	-5.8	3	III	52.6	41.8	49	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1582	NM_006357	Huesken	UBE2E3	10477	AGACAGAUGACUCCCUGACug	GUCAGGGAGUCAUCUGUCU	-2.2	-2.1	-1.9	3	3	3	-41	57.6	13.2	5	Ib	52.6	55.9	83.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1583	NM_006357	Huesken	UBE2E3	10477	AGAUGACUCCCUGACUGUUga	AACAGUCAGGGAGUCAUCU	-0.9	-2.1	0.1	2	1	3	-39.5	53.6	-3.3	4	II	47.4	42.6	58.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1584	NM_006357	Huesken	UBE2E3	10477	AUGACUCCCUGACUGUUGAug	UCAACAGUCAGGGAGUCAU	-2.4	-1.1	2.3	2	1	3	-39.5	71.1	1	5	II	47.4	49.1	74.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1585	NM_006357	Huesken	UBE2E3	10477	UGACUCCCUGACUGUUGAUgu	AUCAACAGUCAGGGAGUCA	-1.1	-2.1	2	0	1	3	-39.5	62	-4	5	II	47.4	45.7	70.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1586	NM_006357	Huesken	UBE2E3	10477	ACUCCCUGACUGUUGAUGUug	ACAUCAACAGUCAGGGAGU	-2.2	-2.2	2	3	2	3	-39.3	70.1	-1.6	5	II	47.4	50.6	69.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1587	NM_006357	Huesken	UBE2E3	10477	CCCUGACUGUUGAUGUUGCag	GCAACAUCAACAGUCAGGG	-3.4	-3.3	2	0	0	3	-39	53.4	5.1	2	II	52.6	39.2	66.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1588	NM_006357	Huesken	UBE2E3	10477	CUGUUGAUGUUGCAGUGAUag	AUCACUGCAACAUCAACAG	-1.1	-2.1	0.6	0	-2	2	-35.6	61.4	-3.6	4	II	42.1	41.8	69.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1589	NM_006357	Huesken	UBE2E3	10477	AGUGAUAGAUUCUGGUGCGga	CGCACCAGAAUCUAUCACU	-2.4	-2.1	1	0	4	3	-37.7	59.3	0.4	5	Ia	47.4	56.6	73.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1590	NM_006357	Huesken	UBE2E3	10477	GAUAGAUUCUGGUGCGGAAag	UUCCGCACCAGAAUCUAUC	-0.9	-2.4	1.5	1	-1	4	-37.9	56.5	-3.8	4	II	47.4	29.4	42.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1591	NM_006357	Huesken	UBE2E3	10477	GAUUCUGGUGCGGAAAGUAac	UACUUUCCGCACCAGAAUC	-1.3	-2.4	1.3	0	-1	4	-37.5	50.8	-6.1	4	II	47.4	35.8	49.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1592	NM_006357	Huesken	UBE2E3	10477	UCUGGUGCGGAAAGUAACCuu	GGUUACUUUCCGCACCAGA	-3.3	-2.4	-0.8	0	3	4	-39.5	53.5	7.1	5	II	52.6	66.2	91.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1593	NM_006357	Huesken	UBE2E3	10477	GGUGCGGAAAGUAACCUUUgg	AAAGGUUACUUUCCGCACC	-0.9	-3.3	-0.8	0	-2	4	-36.8	55	-3.5	4	III	47.4	39.3	50.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1594	NM_006357	Huesken	UBE2E3	10477	CGGAAAGUAACCUUUGGUGgc	CACCAAAGGUUACUUUCCG	-2.1	-2.4	-0.8	-1	0	3	-35.5	62	-1.7	4	II	47.4	45.9	58.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1595	NM_006357	Huesken	UBE2E3	10477	AACCUUUGGUGGCUUAAAUgg	AUUUAAGCCACCAAAGGUU	-1.1	-0.9	-2.3	4	1	3	-33.9	77.7	0.8	4	II	36.8	50	64.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1596	NM_006357	Huesken	UBE2E3	10477	UGGUGGCUUAAAUGGAUAAuc	UUAUCCAUUUAAGCCACCA	-0.9	-2.1	1.8	-1	-2	3	-34.7	69.3	-1.5	6	II	36.8	47.1	28.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1597	NM_006357	Huesken	UBE2E3	10477	GCUUAAAUGGAUAAUCUGAug	UCAGAUUAUCCAUUUAAGC	-2.4	-3.4	1.5	1	-2	2	-31.8	68.7	1.7	5	II	31.6	38.5	38.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1598	NM_006357	Huesken	UBE2E3	10477	CUGAUGAAAAUGUGAUAUCca	GAUAUCACAUUUUCAUCAG	-2.4	-2.1	1.1	-2	-1	1	-30.7	72.7	5.4	5	II	31.6	58.1	57.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1599	NM_006357	Huesken	UBE2E3	10477	UGAAAAUGUGAUAUCCAGAaa	UCUGGAUAUCACAUUUUCA	-2.4	-2.1	0.8	1	1	2	-32.9	77.9	4	7	II	31.6	63.3	68.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1600	NM_006357	Huesken	UBE2E3	10477	AAAACACACCACCUUCAUAua	UAUGAAGGUGGUGUGUUUU	-1.3	-0.9	2.6	2	1	2	-34.3	71.5	0.9	5	II	36.8	49.3	50.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1601	NM_006357	Huesken	UBE2E3	10477	ACACCACCUUCAUAUACAGaa	CUGUAUAUGAAGGUGGUGU	-2.1	-2.2	0.8	2	3	2	-36.1	57.3	-2.4	3	II	42.1	47.7	36.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1602	NM_006357	Huesken	UBE2E3	10477	CAGAACCCGGUGGACCAAGua	CUUGGUCCACCGGGUUCUG	-2.1	-2.1	-4.2	0	-1	5	-42.6	35.7	0.7	1	II	63.2	41.9	68.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1603	NM_006357	Huesken	UBE2E3	10477	UGGACCAAGUAUAGUUGAUcu	AUCAACUAUACUUGGUCCA	-1.1	-2.1	-0.7	0	0	2	-35.1	70.4	-1.2	5	II	36.8	47.7	59.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1604	NM_006357	Huesken	UBE2E3	10477	GACCAAGUAUAGUUGAUCUcc	AGAUCAACUAUACUUGGUC	-2.1	-2.4	-3.3	1	0	2	-34.2	71.9	3.4	3	III	36.8	43.1	52.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1605	NM_006357	Huesken	UBE2E3	10477	UAUAGUUGAUCUCCAUUCAua	UGAAUGGAGAUCAACUAUA	-2.1	-1.3	0.1	1	1	2	-33.3	89.1	-0.7	8	II	31.6	65	90.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1606	NM_006357	Huesken	UBE2E3	10477	AUUCAUAAAUGUUAUCUCCuu	GGAGAUAACAUUUAUGAAU	-3.3	-1.1	1.6	2	4	2	-29.6	93.9	13.1	7	Ia	26.3	73.7	75.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1607	NM_006357	Huesken	UBE2E3	10477	UCAUAAAUGUUAUCUCCUUua	AAGGAGAUAACAUUUAUGA	-0.9	-2.4	1.6	1	1	2	-30.6	76.8	-1.3	7	II	26.3	60.8	52	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1608	NM_006357	Huesken	UBE2E3	10477	UAUCUCCUUUAGGCCCAGCac	GCUGGGCCUAAAGGAGAUA	-3.4	-1.3	-0.7	1	4	5	-40.8	68.3	9.7	6	Ib	52.6	65.9	67.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1609	NM_006357	Huesken	UBE2E3	10477	UCCUUUAGGCCCAGCACUGca	CAGUGCUGGGCCUAAAGGA	-2.1	-2.4	-0.7	0	2	5	-42.4	52.9	-7.3	5	Ia	57.9	59.5	73.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1610	NM_006357	Huesken	UBE2E3	10477	AGGCCCAGCACUGCAAUUAgg	UAAUUGCAGUGCUGGGCCU	-1.3	-2.1	0	3	-2	5	-41.2	53	-3.1	5	II	52.6	43.1	47.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1611	NM_006357	Huesken	UBE2E3	10477	CCAGCACUGCAAUUAGGAGga	CUCCUAAUUGCAGUGCUGG	-2.1	-3.3	0.8	0	1	2	-39	48.7	2.6	1	II	52.6	35	51.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1612	NM_006357	Huesken	UBE2E3	10477	GCACUGCAAUUAGGAGGAGga	CUCCUCCUAAUUGCAGUGC	-2.1	-3.4	2.1	0	1	2	-39.3	27.6	0	2	II	52.6	27	34.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1613	NM_006357	Huesken	UBE2E3	10477	CACUGCAAUUAGGAGGAGGau	CCUCCUCCUAAUUGCAGUG	-3.3	-2.1	2.1	-1	0	2	-39.2	52.7	0.3	3	II	52.6	46.8	62.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1614	NM_006357	Huesken	UBE2E3	10477	AUUAGGAGGAGGAUCAAGGgu	CCUUGAUCCUCCUCCUAAU	-3.3	-1.1	1.9	2	5	2	-38.6	66.8	-0.3	7	Ia	47.4	70.3	81.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1615	NM_006357	Huesken	UBE2E3	10477	AUCAAGGGUUAUUUCAGCUag	AGCUGAAAUAACCCUUGAU	-2.1	-1.1	3.4	1	3	3	-34.6	77.9	6.4	6	II	36.8	61	82	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1616	NM_006357	Huesken	UBE2E3	10477	GGUUAUUUCAGCUAGCUCCuu	GGAGCUAGCUGAAAUAACC	-3.3	-3.3	0.5	2	1	2	-37.3	80.7	7.8	6	II	47.4	58.8	80.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1617	NM_006357	Huesken	UBE2E3	10477	UAUUUCAGCUAGCUCCUUCug	GAAGGAGCUAGCUGAAAUA	-2.4	-1.3	0.5	1	4	2	-36.3	90.6	14.4	9	Ia	42.1	73.9	88.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1618	NM_006357	Huesken	UBE2E3	10477	UUCAGCUAGCUCCUUCUGAau	UCAGAAGGAGCUAGCUGAA	-2.4	-0.9	-1.7	2	1	2	-39.6	70.4	-1.4	6	II	47.4	60.3	87.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1619	NM_006357	Huesken	UBE2E3	10477	CAGCUAGCUCCUUCUGAAUuc	AUUCAGAAGGAGCUAGCUG	-1.1	-2.1	0.5	0	-3	2	-38.3	58.9	-5.3	3	III	47.4	36.7	42.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1620	NM_006357	Huesken	UBE2E3	10477	AGCUAGCUCCUUCUGAAUUcu	AAUUCAGAAGGAGCUAGCU	-0.9	-2.1	0.7	2	0	2	-37.1	69.4	6.5	4	II	42.1	46.1	71.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1621	NM_006357	Huesken	UBE2E3	10477	UUCUGAAUUCUUUUAGCACua	GUGCUAAAAGAAUUCAGAA	-2.2	-0.9	2.6	0	4	2	-31.1	89.6	12.8	6	Ia	31.6	70.2	81.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1622	NM_006357	Huesken	UBE2E3	10477	ACUAGUGGAUAACUUAGCAgu	UGCUAAGUUAUCCACUAGU	-2.1	-2.2	0.4	1	2	2	-35.1	68.2	3.3	5	II	36.8	49.3	82.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1623	NM_006357	Huesken	UBE2E3	10477	GCAGUGGUUUUGCUAGAGAgu	UCUCUAGCAAAACCACUGC	-2.4	-3.4	-0.3	0	-1	2	-38	46.5	1	3	III	47.4	33.6	35.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1624	NM_006357	Huesken	UBE2E3	10477	GUGGUUUUGCUAGAGAGUUug	AACUCUCUAGCAAAACCAC	-0.9	-2.2	2.6	2	-1	2	-35.6	57.1	-4	3	II	42.1	47	52.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1625	NM_006357	Huesken	UBE2E3	10477	GUUUUGCUAGAGAGUUUGGug	CCAAACUCUCUAGCAAAAC	-3.3	-2.2	2.6	-1	2	2	-34.3	69.7	-0.3	5	II	42.1	46.9	69.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1626	NM_006357	Huesken	UBE2E3	10477	UUUGCUAGAGAGUUUGGUGuu	CACCAAACUCUCUAGCAAA	-2.1	-0.9	2.6	0	5	2	-35.5	84.4	4.6	6	Ia	42.1	72.1	84.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1627	NM_006357	Huesken	UBE2E3	10477	UUGCUAGAGAGUUUGGUGUuu	ACACCAAACUCUCUAGCAA	-2.2	-0.9	2.6	2	2	2	-36.8	79.9	1.4	8	II	42.1	65.2	90.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1628	NM_006357	Huesken	UBE2E3	10477	CUGGGUGGCAGAAGGUUUUcu	AAAACCUUCUGCCACCCAG	-0.9	-2.1	0.6	-1	-3	3	-39.6	45.8	-8.6	4	III	52.6	42.6	32.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1629	NM_006357	Huesken	UBE2E3	10477	UCUUUCCUCUUGUUCUUCAgg	UGAAGAACAAGAGGAAAGA	-2.1	-2.4	2.1	1	1	2	-34.6	88.4	-1.4	7	II	36.8	57.4	89.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1630	NM_006357	Huesken	UBE2E3	10477	UCCUCUUGUUCUUCAGGCUcu	AGCCUGAAGAACAAGAGGA	-2.1	-2.4	-0.9	1	1	3	-39.2	75.8	-3.3	5	II	47.4	56.4	89	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1631	NM_006357	Huesken	UBE2E3	10477	UGGAGCGGCUGGGUCUCGCug	GCGAGACCCAGCCGCUCCA	-3.4	-2.1	-2.1	1	4	5	-48.1	43.6	9.7	3	II	73.7	57.1	69.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1632	NM_006357	Huesken	UBE2E3	10477	CGGCUGGGUCUCGCUGGUCcg	GACCAGCGAGACCCAGCCG	-2.4	-2.4	-1	0	-1	4	-46.9	25	3.1	0	II	73.7	37.8	54.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1633	NM_006357	Huesken	UBE2E3	10477	CGCAUCUGAACUGCCACUGcu	CAGUGGCAGUUCAGAUGCG	-2.1	-2.4	-2.4	0	-1	3	-40.5	57.5	-1.3	2	II	57.9	47.2	53	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1634	NM_021988	Huesken	UBE2V1	7335	GUCCUUCGGGCGGCUGAGGga	CCUCAGCCGCCCGAAGGAC	-3.3	-2.2	-0.9	2	1	8	-46.8	32.7	-2.4	1	II	73.7	37.3	55.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1635	NM_021988	Huesken	UBE2V1	7335	CCUUCGGGCGGCUGAGGGAgu	UCCCUCAGCCGCCCGAAGG	-2.4	-3.3	0.2	-1	-2	8	-47.9	27.8	-8.1	2	III	73.7	24	46.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1636	NM_021988	Huesken	UBE2V1	7335	UUUCAUAUUUUCUUUAGACau	GUCUAAAGAAAAUAUGAAA	-2.2	-0.9	1	1	5	1	-26.8	101.1	10.1	7	Ia	21.1	77.5	75.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1637	NM_021988	Huesken	UBE2V1	7335	UUCUUUAGACAUCAUUAGGcg	CCUAAUGAUGUCUAAAGAA	-3.3	-0.9	1	0	3	2	-31.6	95.8	7.7	7	Ia	31.6	74.1	95.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1638	NM_021988	Huesken	UBE2V1	7335	UCUUUAGACAUCAUUAGGCgc	GCCUAAUGAUGUCUAAAGA	-3.4	-2.4	1.8	1	5	3	-34.1	81.4	4.8	8	Ia	36.8	73.4	94.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1639	NM_021988	Huesken	UBE2V1	7335	AGACAUCAUUAGGCGCCGAag	UCGGCGCCUAAUGAUGUCU	-2.4	-2.1	-1.4	2	1	7	-40.4	43.2	1.3	3	II	52.6	40.6	78.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1640	NM_021988	Huesken	UBE2V1	7335	UUAGGCGCCGAAGCUCUUGca	CAAGAGCUUCGGCGCCUAA	-2.1	-0.9	-4.5	1	3	7	-40.9	54.3	2.3	5	II	57.9	68.1	84.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1641	NM_021988	Huesken	UBE2V1	7335	UAGGCGCCGAAGCUCUUGCag	GCAAGAGCUUCGGCGCCUA	-3.4	-1.3	-4.5	1	4	7	-43.4	63.4	14.4	4	II	63.2	67.3	82.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1642	NM_021988	Huesken	UBE2V1	7335	CGAAGCUCUUGCAGGACAAcu	UUGUCCUGCAAGAGCUUCG	-0.9	-2.4	-0.5	-1	-3	2	-39.3	43.7	-10.7	3	III	52.6	30.2	51.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1643	NM_021988	Huesken	UBE2V1	7335	CUCUUGCAGGACAACUUUGau	CAAAGUUGUCCUGCAAGAG	-2.1	-2.1	-0.1	0	-1	2	-36.3	60.8	-4.6	4	II	47.4	50.3	71.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1644	NM_021988	Huesken	UBE2V1	7335	UCUUGCAGGACAACUUUGAug	UCAAAGUUGUCCUGCAAGA	-2.4	-2.4	-0.1	1	0	2	-36.6	66.9	-8.7	8	II	42.1	55.6	89.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1645	NM_021988	Huesken	UBE2V1	7335	GGACAACUUUGAUGCUAUAug	UAUAGCAUCAAAGUUGUCC	-1.3	-3.3	-1.4	0	-3	2	-33.9	50.3	-1.1	1	III	36.8	24	47	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1646	NM_021988	Huesken	UBE2V1	7335	ACAACUUUGAUGCUAUAUGaa	CAUAUAGCAUCAAAGUUGU	-2.1	-2.2	-1.3	3	3	2	-31.4	85.8	4.7	5	Ia	31.6	66.1	77.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1647	NM_021988	Huesken	UBE2V1	7335	CAACUUUGAUGCUAUAUGAau	UCAUAUAGCAUCAAAGUUG	-2.4	-2.1	0	1	-2	2	-31.6	78.4	-8.1	5	II	31.6	49.3	49	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1648	NM_021988	Huesken	UBE2V1	7335	CUUUGAUGCUAUAUGAAUUcu	AAUUCAUAUAGCAUCAAAG	-0.9	-2.1	3.2	1	-1	2	-29.3	85.6	-0.9	4	II	26.3	50.8	70	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1649	NM_021988	Huesken	UBE2V1	7335	UGAUGCUAUAUGAAUUCUGcc	CAGAAUUCAUAUAGCAUCA	-2.1	-2.1	2.1	1	3	2	-32	80.2	-2.6	7	Ib	31.6	73.2	90	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1650	NM_021988	Huesken	UBE2V1	7335	GAUGCUAUAUGAAUUCUGCca	GCAGAAUUCAUAUAGCAUC	-3.4	-2.4	0.1	0	3	2	-33.3	80.1	7.1	4	II	36.8	56.6	82	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1651	NM_021988	Huesken	UBE2V1	7335	UGCUAUAUGAAUUCUGCCAuu	UGGCAGAAUUCAUAUAGCA	-2.1	-2.1	0.1	1	0	3	-35.2	87.5	4.3	7	II	36.8	62.4	89.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1652	NM_021988	Huesken	UBE2V1	7335	GAAUUCUGCCAUUUUGCUAgc	UAGCAAAAUGGCAGAAUUC	-1.3	-2.4	-1.3	2	0	3	-33.4	83.9	3.9	4	II	36.8	44.5	63	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1653	NM_021988	Huesken	UBE2V1	7335	UUCUGCCAUUUUGCUAGCAcu	UGCUAGCAAAAUGGCAGAA	-2.1	-0.9	-4.6	0	1	3	-36.6	67.7	-0.7	4	II	42.1	54.8	71.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1654	NM_021988	Huesken	UBE2V1	7335	UGCCAUUUUGCUAGCACUGau	CAGUGCUAGCAAAAUGGCA	-2.1	-2.1	-4	1	2	3	-37.6	65.4	0.8	4	Ib	47.4	64.1	87.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1655	NM_021988	Huesken	UBE2V1	7335	UUGCUAGCACUGAUAUGGCuc	GCCAUAUCAGUGCUAGCAA	-3.4	-0.9	0.4	1	5	3	-38.5	64	7.1	6	Ib	47.4	69.1	92.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1656	NM_021988	Huesken	UBE2V1	7335	GCUAGCACUGAUAUGGCUCuu	GAGCCAUAUCAGUGCUAGC	-2.4	-3.4	-0.5	0	2	3	-40	61.1	12.5	3	II	52.6	47.9	90.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1657	NM_021988	Huesken	UBE2V1	7335	CUAGCACUGAUAUGGCUCUug	AGAGCCAUAUCAGUGCUAG	-2.1	-2.1	-0.5	-1	-1	3	-38.7	54.5	-6	4	III	47.4	46.8	90.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1658	NM_021988	Huesken	UBE2V1	7335	UAGCACUGAUAUGGCUCUUgg	AAGAGCCAUAUCAGUGCUA	-0.9	-1.3	-0.5	1	1	3	-37.5	65.2	4.1	6	II	42.1	55.2	84.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1659	NM_021988	Huesken	UBE2V1	7335	UAUGGCUCUUGGGUCCACCac	GGUGGACCCAAGAGCCAUA	-3.3	-1.3	-2.3	1	5	3	-42.9	65.9	9.7	4	Ib	57.9	72.2	84.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1660	NM_021988	Huesken	UBE2V1	7335	UUGGGUCCACCACUCCAUUag	AAUGGAGUGGUGGACCCAA	-0.9	-0.9	-1.3	0	1	3	-41.3	57.4	-1.6	3	II	52.6	57.6	83.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1661	NM_021988	Huesken	UBE2V1	7335	CCACCACUCCAUUAGAACUau	AGUUCUAAUGGAGUGGUGG	-2.1	-3.3	0.3	1	-2	2	-38.1	60.1	-0.7	1	III	47.4	40.4	56.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1662	NM_021988	Huesken	UBE2V1	7335	GUUACAAAUCUUACAAAGGgg	CCUUUGUAAGAUUUGUAAC	-3.3	-2.2	1.8	0	2	2	-29.8	74.8	0.4	4	II	31.6	57.3	63.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1663	NM_021988	Huesken	UBE2V1	7335	GGUCCACAUUCUAUUUUAAgg	UUAAAAUAGAAUGUGGACC	-0.9	-3.3	3.2	1	-2	2	-31.4	67.9	-3.3	2	III	31.6	23.7	38.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1664	NM_021988	Huesken	UBE2V1	7335	UAUUUUAAGGCUGUAUAUUcg	AAUAUACAGCCUUAAAAUA	-0.9	-1.3	2.6	1	2	3	-28.2	96.4	-1	8	II	21.1	68.7	82.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1665	NM_021988	Huesken	UBE2V1	7335	UUUUAAGGCUGUAUAUUCGgu	CGAAUAUACAGCCUUAAAA	-2.4	-0.9	2.6	1	5	3	-30.6	90.9	5.5	9	Ia	31.6	74.7	89.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1666	NM_021988	Huesken	UBE2V1	7335	UAAGGCUGUAUAUUCGGUUuu	AACCGAAUAUACAGCCUUA	-0.9	-1.3	3.4	1	3	3	-34.3	76.4	-1.6	7	II	36.8	70.6	96.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1667	NM_021988	Huesken	UBE2V1	7335	CAUAAAUUGUUCUUGGAGGcc	CCUCCAAGAACAAUUUAUG	-3.3	-2.1	2.5	1	2	2	-32.1	79	0.7	5	II	36.8	57.7	63.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1668	NM_021988	Huesken	UBE2V1	7335	AUAAAUUGUUCUUGGAGGCcc	GCCUCCAAGAACAAUUUAU	-3.4	-1.1	2.5	1	5	3	-33.4	79.7	10.8	7	Ia	36.8	68.8	76.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1669	NM_021988	Huesken	UBE2V1	7335	AAUUGUUCUUGGAGGCCCAau	UGGGCCUCCAAGAACAAUU	-2.1	-0.9	-1.3	1	2	5	-38.8	62.7	-6.3	5	II	47.4	53	57.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1670	NM_021988	Huesken	UBE2V1	7335	GGAGGCCCAAUUAUCAUCCcu	GGAUGAUAAUUGGGCCUCC	-3.3	-3.3	0.8	0	2	5	-39.8	58.6	10.2	3	II	52.6	52.7	70.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1671	NM_021988	Huesken	UBE2V1	7335	UUAUCAUCCCUGUCCAUCUug	AGAUGGACAGGGAUGAUAA	-2.1	-0.9	0.8	2	2	3	-37.7	84.5	-4	8	II	42.1	73.6	90	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1672	NM_021988	Huesken	UBE2V1	7335	CAUCCCUGUCCAUCUUGUAag	UACAAGAUGGACAGGGAUG	-1.3	-2.1	1.9	1	-2	3	-38.5	61.6	-8.1	3	III	47.4	37.3	52.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1673	NM_021988	Huesken	UBE2V1	7335	UCAUGUCUUCGUCAUCUUCua	GAAGAUGACGAAGACAUGA	-2.4	-2.4	1	0	2	2	-35.7	79	12.8	6	Ib	42.1	64.3	95	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1674	NM_021988	Huesken	UBE2V1	7335	UGUCUUCGUCAUCUUCUAGac	CUAGAAGAUGACGAAGACA	-2.1	-2.1	2.8	1	3	2	-35.6	83.5	10.1	6	Ib	42.1	59	88.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1675	NM_021988	Huesken	UBE2V1	7335	GUCUUCGUCAUCUUCUAGAcc	UCUAGAAGAUGACGAAGAC	-2.4	-2.2	1.2	1	-1	2	-35.9	77.1	-3.8	5	III	42.1	46	58	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1676	NM_021988	Huesken	UBE2V1	7335	UCUUCGUCAUCUUCUAGACcc	GUCUAGAAGAUGACGAAGA	-2.2	-2.4	-2.7	1	3	2	-35.9	85.2	8.1	5	Ib	42.1	61.1	92	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1677	NM_021988	Huesken	UBE2V1	7335	UUCGUCAUCUUCUAGACCCca	GGGUCUAGAAGAUGACGAA	-3.3	-0.9	-2.7	1	4	3	-38	77.6	5.1	5	Ib	47.4	79.5	96.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1678	NM_021988	Huesken	UBE2V1	7335	CGUCAUCUUCUAGACCCCAgc	UGGGGUCUAGAAGAUGACG	-2.1	-2.4	-2.7	0	-2	4	-40.1	40.3	-3.1	1	III	52.6	37.9	38.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1679	NM_021988	Huesken	UBE2V1	7335	CAUCUUCUAGACCCCAGCUaa	AGCUGGGGUCUAGAAGAUG	-2.1	-2.1	-0.8	0	0	4	-40.7	62.6	-3.6	3	II	52.6	47.7	73	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1680	NM_021988	Huesken	UBE2V1	7335	AUCUUCUAGACCCCAGCUAac	UAGCUGGGGUCUAGAAGAU	-1.3	-1.1	-0.8	3	0	4	-39.9	66	-6.1	7	II	47.4	51.4	82.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1681	NM_021988	Huesken	UBE2V1	7335	GCUAACUGUGCCAUCUCCUac	AGGAGAUGGCACAGUUAGC	-2.1	-3.4	1	1	1	3	-40.6	55.9	-6.2	4	II	52.6	44.3	60.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1682	NM_021988	Huesken	UBE2V1	7335	UAACUGUGCCAUCUCCUACuc	GUAGGAGAUGGCACAGUUA	-2.2	-1.3	0.8	3	4	3	-38.6	81.3	17.5	8	Ia	47.4	72.9	88.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1683	NM_021988	Huesken	UBE2V1	7335	UGUGCCAUCUCCUACUCCUuu	AGGAGUAGGAGAUGGCACA	-2.1	-2.1	0.6	1	2	3	-42	68	-8.7	5	II	52.6	61.4	92.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1684	NM_021988	Huesken	UBE2V1	7335	CCAUCUCCUACUCCUUUCUgg	AGAAAGGAGUAGGAGAUGG	-2.1	-3.3	3	-1	-2	2	-38.5	71.5	-2.9	4	III	47.4	43.6	58.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1685	NM_021988	Huesken	UBE2V1	7335	UACUCCUUUCUGGCCUUCUuc	AGAAGGCCAGAAAGGAGUA	-2.1	-1.3	-0.5	1	1	4	-39.3	78.4	-4	7	II	47.4	64.9	86.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1686	NM_021988	Huesken	UBE2V1	7335	GGCCUUCUUCGAGUUCUUCca	GAAGAACUCGAAGAAGGCC	-2.4	-3.3	1	1	0	4	-38.6	57.8	9.7	2	II	52.6	38.3	53.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1687	NM_021988	Huesken	UBE2V1	7335	CCUUCUUCGAGUUCUUCCAac	UGGAAGAACUCGAAGAAGG	-2.1	-3.3	1	1	-2	2	-37.3	77.5	-2.7	4	II	47.4	43.7	59.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1688	NM_021988	Huesken	UBE2V1	7335	GUUCUUCCAACAGUCGGAAau	UUCCGACUGUUGGAAGAAC	-0.9	-2.2	-3.4	1	0	3	-37.2	55.8	-3.8	3	II	47.4	34.3	52.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1689	NM_021988	Huesken	UBE2V1	7335	UUCCAACAGUCGGAAAUUGcg	CAAUUUCCGACUGUUGGAA	-2.1	-0.9	-2.8	2	2	3	-34.6	56.1	0.4	5	Ib	42.1	58.5	95.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1690	NM_021988	Huesken	UBE2V1	7335	CAACAGUCGGAAAUUGCGAgg	UCGCAAUUUCCGACUGUUG	-2.4	-2.1	0.2	2	0	3	-36.2	51.5	-1	4	II	47.4	46.5	85.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1691	NM_021988	Huesken	UBE2V1	7335	CAGUCGGAAAUUGCGAGGGac	CCCUCGCAAUUUCCGACUG	-3.3	-2.1	0.3	-1	1	3	-39.7	52.5	1	3	II	57.9	51.3	84.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1692	NM_021988	Huesken	UBE2V1	7335	UCGGAAAUUGCGAGGGACUuu	AGUCCCUCGCAAUUUCCGA	-2.1	-2.4	0.8	-1	0	3	-40	44.5	-6.2	5	II	52.6	54.2	96	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1693	NM_021988	Huesken	UBE2V1	7335	AUUGCGAGGGACUUUUACUcc	AGUAAAAGUCCCUCGCAAU	-2.1	-1.1	1.1	2	3	3	-36	74.9	-1.7	5	II	42.1	61.7	91	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1694	NM_021988	Huesken	UBE2V1	7335	UGCGAGGGACUUUUACUCCuu	GGAGUAAAAGUCCCUCGCA	-3.3	-2.1	-0.8	0	3	3	-39.7	63.4	15.5	6	II	52.6	65.9	88.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1695	NM_021988	Huesken	UBE2V1	7335	GAGGGACUUUUACUCCUUUgc	AAAGGAGUAAAAGUCCCUC	-0.9	-2.4	-1	0	-1	3	-35.7	54.5	0.8	1	III	42.1	37.6	65.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1696	NM_021988	Huesken	UBE2V1	7335	UUUACUCCUUUGCAGUGAAau	UUCACUGCAAAGGAGUAAA	-0.9	-0.9	0	0	1	2	-34.3	76.3	-1.4	6	II	36.8	53.9	81.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1697	NM_021988	Huesken	UBE2V1	7335	UACUCCUUUGCAGUGAAAUuu	AUUUCACUGCAAAGGAGUA	-1.1	-1.3	-0.9	1	1	2	-34.5	82.9	-4	6	II	36.8	59.9	95	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1698	NM_021988	Huesken	UBE2V1	7335	CUCCUUUGCAGUGAAAUUUuc	AAAUUUCACUGCAAAGGAG	-0.9	-2.1	0.3	2	-3	2	-32.8	74.7	-3	5	II	36.8	51.1	45.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1699	NM_021988	Huesken	UBE2V1	7335	CCUUUGCAGUGAAAUUUUCua	GAAAAUUUCACUGCAAAGG	-2.4	-3.3	0.3	0	-1	2	-31.6	65.8	2.8	4	II	36.8	44.4	83.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1700	NM_021988	Huesken	UBE2V1	7335	UUGCAGUGAAAUUUUCUAGgu	CUAGAAAAUUUCACUGCAA	-2.1	-0.9	1	2	3	2	-30.8	94.3	10.4	8	Ib	31.6	73.5	96	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1701	NM_021988	Huesken	UBE2V1	7335	GCAGUGAAAUUUUCUAGGUuc	ACCUAGAAAAUUUCACUGC	-2.2	-3.4	1	0	0	2	-33.3	62.6	-1	3	III	36.8	41.8	36.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1702	NM_021988	Huesken	UBE2V1	7335	CAGUGAAAUUUUCUAGGUUca	AACCUAGAAAAUUUCACUG	-0.9	-2.1	1	-1	-1	2	-30.8	68.4	1.8	3	II	31.6	43.5	49.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1703	NM_021988	Huesken	UBE2V1	7335	GUGAAAUUUUCUAGGUUCAag	UGAACCUAGAAAAUUUCAC	-2.1	-2.2	0.9	0	-2	2	-31.1	70.7	-3	5	II	31.6	42.7	43	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1704	NM_021988	Huesken	UBE2V1	7335	GAAAUUUUCUAGGUUCAAGuc	CUUGAACCUAGAAAAUUUC	-2.1	-2.4	1.9	2	2	2	-29.8	85.9	4.6	5	II	31.6	54.6	53.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1705	NM_021988	Huesken	UBE2V1	7335	AUUUUCUAGGUUCAAGUCUuc	AGACUUGAACCUAGAAAAU	-2.1	-1.1	1.4	3	2	2	-32.3	86.6	1.5	8	II	31.6	66	71.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1706	NM_021988	Huesken	UBE2V1	7335	UCUAGGUUCAAGUCUUCCUuc	AGGAAGACUUGAACCUAGA	-2.1	-2.4	-0.2	2	2	2	-37.2	82.8	-1.7	7	II	42.1	67.6	78	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1707	NM_021988	Huesken	UBE2V1	7335	AGUCUUCCUUCAUCACUCAgu	UGAGUGAUGAAGGAAGACU	-2.1	-2.1	1.3	2	0	2	-37.3	65.5	-6.1	5	II	42.1	46.8	62.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1708	NM_022005	Huesken	Fxyd6	53826	GCUUGGUUCGUUUCCAAGGga	CCUUGGAAACGAACCAAGC	-3.3	-3.4	-4.3	2	1	2	-37.8	64.9	3	2	II	52.6	50.2	85.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1709	NM_022005	Huesken	Fxyd6	53826	CAAGGGAACACAAUGGGCAgg	UGCCCAUUGUGUUCCCUUG	-2.1	-2.1	1.9	0	0	4	-39.8	44.3	-8.4	4	III	52.6	49.7	95.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1710	NM_022005	Huesken	Fxyd6	53826	GGUGGGGCAGGCUCUGGUGug	CACCAGAGCCUGCCCCACC	-2.1	-3.3	0.8	0	1	5	-48.1	32.3	-2.4	1	II	73.7	34.5	90.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1711	NM_022005	Huesken	Fxyd6	53826	GUGGGGCAGGCUCUGGUGUga	ACACCAGAGCCUGCCCCAC	-2.2	-2.2	0.8	1	0	5	-47	36.2	1.4	1	III	68.4	34.2	72.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1712	NM_022005	Huesken	Fxyd6	53826	GUGUGAGUUUCCACUCUGGug	CCAGAGUGGAAACUCACAC	-3.3	-2.2	-5.9	0	1	2	-39.1	54	-7.3	3	II	52.6	46.7	95.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1713	NM_022005	Huesken	Fxyd6	53826	GUGAGUUUCCACUCUGGUGac	CACCAGAGUGGAAACUCAC	-2.1	-2.2	-5.9	2	1	2	-39.1	68.4	-0.1	2	II	52.6	51.9	92.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1714	NM_022005	Huesken	Fxyd6	53826	GUUUCCACUCUGGUGACCUuu	AGGUCACCAGAGUGGAAAC	-2.1	-2.2	-1.7	0	2	2	-40.3	62.2	-1.6	3	II	52.6	48.2	94.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1715	NM_022005	Huesken	Fxyd6	53826	CUCUGGUGACCUUUGACUCcc	GAGUCAAAGGUCACCAGAG	-2.4	-2.1	0.5	0	1	2	-39.3	67.9	8.4	3	II	52.6	52.8	85.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1716	NM_022005	Huesken	Fxyd6	53826	ACCUUUGACUCCCGUAGGCgu	GCCUACGGGAGUCAAAGGU	-3.4	-2.2	-3.3	1	3	4	-41.9	53.6	5.1	3	Ib	57.9	49.7	91.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1717	NM_022005	Huesken	Fxyd6	53826	UUGACUCCCGUAGGCGUUUgc	AAACGCCUACGGGAGUCAA	-0.9	-0.9	-3.3	0	0	4	-39.8	56.5	-4	5	II	52.6	57.6	93.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1718	NM_022005	Huesken	Fxyd6	53826	CACGGGUGUGCAUACCCUGuu	CAGGGUAUGCACACCCGUG	-2.1	-2.1	-5.6	0	0	4	-42.8	39.1	-4.4	0	II	63.2	49.9	70.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1719	NM_022005	Huesken	Fxyd6	53826	GGUGUGCAUACCCUGUUGCuc	GCAACAGGGUAUGCACACC	-3.4	-3.3	-1.9	0	2	3	-41.4	56.6	7.4	2	II	57.9	44.8	72.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1720	NM_022005	Huesken	Fxyd6	53826	CAUACCCUGUUGCUCUCUCcc	GAGAGAGCAACAGGGUAUG	-2.4	-2.1	1	0	2	3	-39.6	66.4	10.1	3	II	52.6	48.9	85.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1721	NM_022005	Huesken	Fxyd6	53826	CCUGUUGCUCUCUCCCGCUgc	AGCGGGAGAGAGCAACAGG	-2.1	-3.3	-1.9	-1	-1	5	-44.1	46.1	-8.3	1	III	63.2	43.8	43.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1722	NM_022005	Huesken	Fxyd6	53826	GUUGCUCUCUCCCGCUGCCcc	GGCAGCGGGAGAGAGCAAC	-3.3	-2.2	-1.9	0	3	5	-45.4	47.3	5.1	0	II	68.4	44	61.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1723	NM_022005	Huesken	Fxyd6	53826	CUCUCUCCCGCUGCCCCUGaa	CAGGGGCAGCGGGAGAGAG	-2.1	-2.1		0	0	5	-47.6	45.3	-1.3	1	II	73.7	43.9	66.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1724	NM_022005	Huesken	Fxyd6	53826	CACUCCGACCCCUGACAGGca	CCUGUCAGGGGUCGGAGUG	-3.3	-2.1	-1.9	-1	0	4	-45.3	43	-6.7	1	II	68.4	40.7	72.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1725	NM_022005	Huesken	Fxyd6	53826	ACCCCUGACAGGCAGGGGAaa	UCCCCUGCCUGUCAGGGGU	-2.4	-2.2	-9.7	3	0	4	-48.3	38.3	-1.4	2	II	68.4	38.7	42.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1726	NM_022005	Huesken	Fxyd6	53826	GGGAAAGAAACUGUAGUCUgc	AGACUACAGUUUCUUUCCC	-2.1	-3.3	0.2	0	-1	3	-35.8	57.6	1.7	5	III	42.1	39.9	55.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1727	NM_022005	Huesken	Fxyd6	53826	AAAGAAACUGUAGUCUGCCag	GGCAGACUACAGUUUCUUU	-3.3	-0.9	-0.1	1	6	3	-35.6	60.8	12.4	6	Ia	42.1	71.2	86	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1728	NM_022005	Huesken	Fxyd6	53826	AACUGUAGUCUGCCAGAUUcc	AAUCUGGCAGACUACAGUU	-0.9	-0.9	-1.7	1	0	3	-37	63.4	-1.6	4	II	42.1	52.3	81.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1729	NM_022005	Huesken	Fxyd6	53826	CAGAUUCCACACCAUGUGGca	CCACAUGGUGUGGAAUCUG	-3.3	-2.1	-4.9	-1	0	2	-39.1	64.6	0.4	3	II	52.6	50.9	40.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1730	NM_022005	Huesken	Fxyd6	53826	CACACCAUGUGGCAGAGAGac	CUCUCUGCCACAUGGUGUG	-2.1	-2.1	-2.4	0	0	3	-41.4	55.5	0.4	1	II	57.9	42	46.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1731	NM_022005	Huesken	Fxyd6	53826	AUGUGGCAGAGAGACAGAGcc	CUCUGUCUCUCUGCCACAU	-2.1	-1.1	1.8	2	3	3	-40.7	47.7	0	5	II	52.6	54.2	62.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1732	NM_022005	Huesken	Fxyd6	53826	GUGGCAGAGAGACAGAGCCac	GGCUCUGUCUCUCUGCCAC	-3.3	-2.2	-3.8	1	2	3	-44.2	41.5	9.8	1	II	63.2	50.6	45.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1733	NM_022005	Huesken	Fxyd6	53826	UGGCAGAGAGACAGAGCCAcc	UGGCUCUGUCUCUCUGCCA	-2.1	-2.1	-3.8	0	0	3	-44.1	35.9	-3.7	3	II	57.9	49.8	76.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1734	NM_022005	Huesken	Fxyd6	53826	GCAGAGAGACAGAGCCACCgg	GGUGGCUCUGUCUCUCUGC	-3.3	-3.4	0.5	-1	1	3	-44.2	30.2	9.8	2	II	63.2	44.3	71.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1735	NM_022005	Huesken	Fxyd6	53826	CCUGCUGCCUGUCCCCUGGgc	CCAGGGGACAGGCAGCAGG	-3.3	-3.3	0.4	0	0	4	-48	46.5	3.4	2	II	73.7	42.3	45.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1736	NM_022005	Huesken	Fxyd6	53826	CCCUGGGCUAUCUCCUGCCac	GGCAGGAGAUAGCCCAGGG	-3.3	-3.3	-3.4	-1	0	4	-46.4	44.1	3.1	1	II	68.4	48.3	67.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1737	NM_022005	Huesken	Fxyd6	53826	CUGCCACAGACCAGCUUCAga	UGAAGCUGGUCUGUGGCAG	-2.1	-2.1	-2.2	0	-3	3	-42.4	38.7	-13	1	III	57.9	35.7	44.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1738	NM_022005	Huesken	Fxyd6	53826	CUUCAGAGAAGGAAGGAGUcc	ACUCCUUCCUUCUCUGAAG	-2.2	-2.1	-0.6	0	-1	2	-38.2	52.5	-5.9	5	II	47.4	48.9	50.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1739	NM_022005	Huesken	Fxyd6	53826	AGAGAAGGAAGGAGUCCUCug	GAGGACUCCUUCCUUCUCU	-2.4	-2.1	-3.3	0	3	2	-40.9	42.7	7.5	5	Ib	52.6	52.6	81.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1740	NM_022005	Huesken	Fxyd6	53826	GCUAGAGAUGGAAGUCUCAga	UGAGACUUCCAUCUCUAGC	-2.1	-3.4	-2.8	-1	-2	2	-38.9	40.8	-6.3	3	III	47.4	31.3	32.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1741	NM_022005	Huesken	Fxyd6	53826	GAAGUCUCAGAAGCAGGGAag	UCCCUGCUUCUGAGACUUC	-2.4	-2.4	1.7	1	0	3	-40.7	46.6	-1.5	4	II	52.6	38.7	67.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1742	NM_022005	Huesken	Fxyd6	53826	AGGGAAGGUGGAUGAAGGCag	GCCUUCAUCCACCUUCCCU	-3.4	-2.1		0	3	3	-42.7	36.7	10.1	3	II	57.9	48.7	85.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1743	NM_022005	Huesken	Fxyd6	53826	GCAGAAGGGCUCCAAAGCCua	GGCUUUGGAGCCCUUCUGC	-3.3	-3.4	-4.5	1	2	4	-43.5	27.1	10.2	1	II	63.2	43.6	73.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1744	NM_022005	Huesken	Fxyd6	53826	GCUCCAAAGCCUAUGGGGAua	UCCCCAUAGGCUUUGGAGC	-2.4	-3.4	-2	2	0	4	-42.8	41.2	-3.3	0	III	57.9	27.5	35.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1745	NM_022005	Huesken	Fxyd6	53826	UGGGGAUAUUGCUCAGAAGuu	CUUCUGAGCAAUAUCCCCA	-2.1	-2.1	1.1	1	1	4	-38.4	60.5	-2.4	4	II	47.4	55.1	93	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1746	NM_022005	Huesken	Fxyd6	53826	UAUUGCUCAGAAGUUAAGUaa	ACUUAACUUCUGAGCAAUA	-2.2	-1.3	-0.2	1	3	2	-32.5	87.5	0.7	7	II	31.6	67.8	90.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1747	NM_022005	Huesken	Fxyd6	53826	GUUAAGUAAGGAGCUCAUUcc	AAUGAGCUCCUUACUUAAC	-0.9	-2.2	-0.2	1	-1	2	-33.7	62.9	-1.3	5	II	36.8	45.2	70.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1748	NM_022005	Huesken	Fxyd6	53826	CUCAUUCCUCAGAGGCAAGaa	CUUGCCUCUGAGGAAUGAG	-2.1	-2.1	-1.2	-2	-1	3	-39.3	55.3	-2.3	2	II	52.6	42.5	59.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1749	NM_022005	Huesken	Fxyd6	53826	AAGAAUUCCUGGGUGUUCUgu	AGAACACCCAGGAAUUCUU	-2.1	-0.9	1	3	2	3	-36.7	77.9	1.1	7	II	42.1	60.9	84.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1750	NM_022005	Huesken	Fxyd6	53826	UGGGUGUUCUGUAAAGGGUgg	ACCCUUUACAGAACACCCA	-2.2	-2.1	2	2	1	3	-38.9	63.6	-3.5	5	II	47.4	58.1	86.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1751	NM_022005	Huesken	Fxyd6	53826	UAAAGGGUGGGGCGGAUUGgg	CAAUCCGCCCCACCCUUUA	-2.1	-1.3	4.3	0	3	7	-41.6	54.1	2.4	7	Ib	57.9	64.6	80.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1752	NM_022005	Huesken	Fxyd6	53826	CCUAAGUGGGCACCCUAAAag	UUUAGGGUGCCCACUUAGG	-0.9	-3.3	-2.5	1	-4	4	-40.1	43.8	-3	3	II	52.6	31.1	48.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1753	NM_022005	Huesken	Fxyd6	53826	AGACGCCUCAAGGGAGGCAau	UGCCUCCCUUGAGGCGUCU	-2.1	-2.1	-8.1	2	1	4	-45.3	33	-1.5	2	II	63.2	37.5	34.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1754	NM_022005	Huesken	Fxyd6	53826	GACGCCUCAAGGGAGGCAAuc	UUGCCUCCCUUGAGGCGUC	-0.9	-2.4	-8.1	1	-2	4	-44.1	42.1	-3.8	1	III	63.2	29.2	37.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1755	NM_022005	Huesken	Fxyd6	53826	CUGAAUCUCCAACUGCAAAcg	UUUGCAGUUGGAGAUUCAG	-0.9	-2.1	1.2	0	-3	2	-35.5	65.1	4	3	II	42.1	38.5	48.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1756	NM_022005	Huesken	Fxyd6	53826	CUUCUAAACUGGUGGAAUCug	GAUUCCACCAGUUUAGAAG	-2.4	-2.1	1.6	0	0	2	-34.7	65.8	5.4	4	II	42.1	50.4	84	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1757	NM_022005	Huesken	Fxyd6	53826	AAUCUGGAGCAAGUUUCUUcu	AAGAAACUUGCUCCAGAUU	-0.9	-0.9	1.6	3	3	2	-34.3	65.8	0.7	6	II	36.8	53.7	79	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1758	NM_022005	Huesken	Fxyd6	53826	UCUGGAGCAAGUUUCUUCUca	AGAAGAAACUUGCUCCAGA	-2.1	-2.4	1.6	0	2	2	-36.8	78.6	1.4	7	II	42.1	62.2	90	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1759	NM_022005	Huesken	Fxyd6	53826	UUUCUUCUCAGAGUCCACAag	UGUGGACUCUGAGAAGAAA	-2.1	-0.9	-0.7	2	2	2	-37.1	77.9	-1.4	7	II	42.1	66.9	85.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1760	NM_022005	Huesken	Fxyd6	53826	UCAGAGUCCACAAGGAACAuc	UGUUCCUUGUGGACUCUGA	-2.1	-2.4	-2.3	1	0	2	-39.3	51.5	-6	6	II	47.4	60.7	94.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1761	NM_022005	Huesken	Fxyd6	53826	GUCCACAAGGAACAUCAGUga	ACUGAUGUUCCUUGUGGAC	-2.2	-2.2	-2.3	2	-1	2	-38.1	49.9	3.4	2	III	47.4	41.2	55.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1762	NM_022005	Huesken	Fxyd6	53826	ACGAACUUUCUCAGCCCCGgg	CGGGGCUGAGAAAGUUCGU	-2.4	-2.2	-4.1	1	3	6	-40.8	49.1	-2.2	3	Ib	57.9	59.8	95.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1763	NM_022005	Huesken	Fxyd6	53826	GAACUUUCUCAGCCCCGGGau	CCCGGGGCUGAGAAAGUUC	-3.3	-2.4	-2.4	2	3	8	-42.8	54.2	4.7	2	II	63.2	52	85.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1764	NM_022005	Huesken	Fxyd6	53826	UCUCAGCCCCGGGAUCACUgg	AGUGAUCCCGGGGCUGAGA	-2.1	-2.4	0.9	2	1	8	-45.7	41.4	-1.3	4	II	63.2	50.2	94.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1765	NM_022005	Huesken	Fxyd6	53826	GGUACAACUCUCCCUCAAGcc	CUUGAGGGAGAGUUGUACC	-2.1	-3.3	0.6	0	0	3	-39.4	55.2	0.1	3	II	52.6	39.2	63.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1766	NM_022005	Huesken	Fxyd6	53826	CAACUCUCCCUCAAGCCUAaa	UAGGCUUGAGGGAGAGUUG	-1.3	-2.1	-2.3	2	-2	3	-40.5	49.9	-10.7	3	II	52.6	46.3	76.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1767	NM_022005	Huesken	Fxyd6	53826	UCUCCCUCAAGCCUAAAUCca	GAUUUAGGCUUGAGGGAGA	-2.4	-2.4	0.6	2	3	3	-38.5	78.9	9.8	6	II	47.4	66.6	90.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1768	NM_022005	Huesken	Fxyd6	53826	UCCCUCAAGCCUAAAUCCAga	UGGAUUUAGGCUUGAGGGA	-2.1	-2.4	1.6	2	0	3	-39.4	56.3	-5.7	5	II	47.4	53.3	81.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1769	NM_022005	Huesken	Fxyd6	53826	CCAGAAAGAGGGGACUAAGgg	CUUAGUCCCCUCUUUCUGG	-2.1	-3.3	0.3	-1	-1	4	-39.2	37.3	0.7	3	II	52.6	39.2	87.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1770	NM_022005	Huesken	Fxyd6	53826	CUAAGGGCUCCUCAGGGACgg	GUCCCUGAGGAGCCCUUAG	-2.2	-2.1	-4.4	-1	1	4	-44.1	43.7	8.5	2	II	63.2	47.7	85.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1771	NM_022005	Huesken	Fxyd6	53826	GGGAGACUCCAGAGAGCAAga	UUGCUCUCUGGAGUCUCCC	-0.9	-3.3	-3	0	-3	3	-43.1	29.3	-4	-1	III	57.9	16.6	58.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1772	NM_022005	Huesken	Fxyd6	53826	ACUCCAGAGAGCAAGAGUAga	UACUCUUGCUCUCUGGAGU	-1.3	-2.2	-3.7	3	0	2	-39.7	48.1	-8.7	4	II	47.4	42.9	57.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1773	NM_022005	Huesken	Fxyd6	53826	AGAGUAGAUGGAGGUCACAgg	UGUGACCUCCAUCUACUCU	-2.1	-2.1	0.8	0	0	2	-39.9	40.2	-3.8	5	II	47.4	43.4	96.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1774	NM_022005	Huesken	Fxyd6	53826	AUGGAGGUCACAGGAGGGCac	GCCCUCCUGUGACCUCCAU	-3.4	-1.1	0.9	1	4	4	-45.2	35	7.8	5	II	63.2	57.5	89	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1775	NM_022005	Huesken	Fxyd6	53826	AUGGGAGAGGAAGCACACAgu	UGUGUGCUUCCUCUCCCAU	-2.1	-1.1	2.5	2	0	3	-41.6	35.9	-1.5	4	II	52.6	48.3	104.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1776	NM_022005	Huesken	Fxyd6	53826	CACAGUUCACAGGAACAAUga	AUUGUUCCUGUGAACUGUG	-1.1	-2.1	-1.9	0	-3	2	-35.4	59.2	-3.7	2	II	42.1	40.6	76.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1777	NM_022005	Huesken	Fxyd6	53826	CAGUUCACAGGAACAAUGAaa	UCAUUGUUCCUGUGAACUG	-2.4	-2.1	-1.9	-1	-3	2	-35.6	63.3	-8.3	4	II	42.1	44.9	66.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1778	NM_022005	Huesken	Fxyd6	53826	UCACAGGAACAAUGAAACGac	CGUUUCAUUGUUCCUGUGA	-2.4	-2.4	-0.5	0	3	2	-34.7	56.3	5	6	II	42.1	64.1	54.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1779	NM_022005	Huesken	Fxyd6	53826	UGAAACGACCACGAACGACca	GUCGUUCGUGGUCGUUUCA	-2.2	-2.1	1	1	3	2	-38	52.6	10.1	7	Ib	52.6	60.2	39.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1780	XM_214061	Huesken	TCAP	8557	UUUGUUUUCAACAUGGUAAgg	UUACCAUGUUGAAAACAAA	-0.9	-0.9	0.4	2	1	2	-29.4	100.8	-4.1	9	II	26.3	70.8	91.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1781	XM_214061	Huesken	TCAP	8557	CAACAUGGUAAGGGUUUUGac	CAAAACCCUUACCAUGUUG	-2.1	-2.1	2	-1	0	3	-33.9	59.1	3	6	II	42.1	50.9	70.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1782	XM_214061	Huesken	TCAP	8557	CAUGGUAAGGGUUUUGACCuc	GGUCAAAACCCUUACCAUG	-3.3	-2.1	-0.9	0	2	3	-36.6	72.9	10.8	3	II	47.4	60.1	84.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1783	XM_214061	Huesken	TCAP	8557	AUGGUAAGGGUUUUGACCUca	AGGUCAAAACCCUUACCAU	-2.1	-1.1	-1.1	2	3	3	-36.6	70	1.4	4	II	42.1	63.9	85.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1784	XM_214061	Huesken	TCAP	8557	CCUCAAAUGCUUAUCAGGUcu	ACCUGAUAAGCAUUUGAGG	-2.2	-3.3	0.1	1	0	2	-35.8	57.2	-0.5	3	II	42.1	43.2	46.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1785	XM_214061	Huesken	TCAP	8557	CGCCUCUUCCUUGAAGUUUug	AAACUUCAAGGAAGAGGCG	-0.9	-2.4	-2.1	2	-4	4	-36.8	58.3	-3	2	III	47.4	37.9	66.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1786	XM_214061	Huesken	TCAP	8557	AUUGCAGGUUUUCCUUCUCag	GAGAAGGAAAACCUGCAAU	-2.4	-1.1	-1.4	1	4	2	-35.5	70.6	12.8	4	Ib	42.1	60.5	79.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1787	XM_214061	Huesken	TCAP	8557	ACACAAAGGGUAUUGCAAGga	CUUGCAAUACCCUUUGUGU	-2.1	-2.2	-1.6	3	3	3	-35.2	55.1	5	4	Ia	42.1	54.4	74.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1788	XM_214061	Huesken	TCAP	8557	CAAAGGGUAUUGCAAGGAUcu	AUCCUUGCAAUACCCUUUG	-1.1	-2.1	1.1	-1	-1	3	-35.5	50.3	-3.6	4	III	42.1	40.1	66.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1789	XM_214061	Huesken	TCAP	8557	CCUCAAAUAUAUGGGGAUAcc	UAUCCCCAUAUAUUUGAGG	-1.3	-3.3	0.8	-1	-4	4	-34.4	52.9	2.3	3	II	36.8	27.6	48.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1790	XM_214061	Huesken	TCAP	8557	UCAAAUAUAUGGGGAUACCaa	GGUAUCCCCAUAUAUUUGA	-3.3	-2.4	-0.4	-1	3	4	-34.5	70.8	10.1	7	Ia	36.8	67.1	76.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1791	XM_214061	Huesken	TCAP	8557	CAACUUGUACAGACGAACAag	UGUUCGUCUGUACAAGUUG	-2.1	-2.1	0.2	0	-2	2	-34.8	63.7	-6	4	II	42.1	49.5	84.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1792	XM_214061	Huesken	TCAP	8557	AACUUGUACAGACGAACAAga	UUGUUCGUCUGUACAAGUU	-0.9	-0.9	-0.7	2	0	2	-33.6	67.7	-1.4	7	II	36.8	48.3	55.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1793	XM_214061	Huesken	TCAP	8557	ACUUGUACAGACGAACAAGac	CUUGUUCGUCUGUACAAGU	-2.1	-2.2	-3.1	1	2	2	-34.8	62.2	-0.1	4	Ia	42.1	54.2	54.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1794	XM_214061	Huesken	TCAP	8557	UACAGACGAACAAGACCUCau	GAGGUCUUGUUCGUCUGUA	-2.4	-1.3	0.4	-1	3	2	-37.7	52.6	2.5	6	Ib	47.4	61.1	72.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1795	XM_214061	Huesken	TCAP	8557	GACCUCAUCUCCCAUACCGgg	CGGUAUGGGAGAUGAGGUC	-2.4	-2.4	1.6	2	2	3	-41.5	56.4	-2.3	2	II	57.9	50.6	84.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1796	XM_214061	Huesken	TCAP	8557	UCUCCCAUACCGGGUUCCGuu	CGGAACCCGGUAUGGGAGA	-2.4	-2.4	-3.7	0	4	5	-43.7	50.4	-2.4	3	II	63.2	56.1	49.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1797	XM_214061	Huesken	TCAP	8557	AAAAUGAGUUAGGCUGUCCca	GGACAGCCUAACUCAUUUU	-3.3	-0.9	-0.2	1	4	3	-35.7	72.2	9.7	8	Ia	42.1	70	62.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1798	XM_214061	Huesken	TCAP	8557	CAAACUCAUCAGGCAGGUUau	AACCUGCCUGAUGAGUUUG	-0.9	-2.1	1.9	-1	-1	3	-37.7	54.3	-3.7	3	II	47.4	40.1	52	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1799	XM_214061	Huesken	TCAP	8557	GCAGGUUAUAAUAGAUAGUgu	ACUAUCUAUUAUAACCUGC	-2.2	-3.4	2.8	0	-1	2	-32.2	64.2	-1.2	3	III	31.6	43.4	42.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1800	XM_214061	Huesken	TCAP	8557	AGUGUAGCACAUAAAAUUUaa	AAAUUUUAUGUGCUACACU	-0.9	-2.1	0.2	1	0	2	-29.8	75	-1.2	6	II	26.3	52.8	46.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1801	XM_214061	Huesken	TCAP	8557	AUACAUCUCUCCUCCUUUGgu	CAAAGGAGGAGAGAUGUAU	-2.1	-1.1	3.7	3	3	2	-36.3	75	-2	6	Ia	42.1	62.8	99.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1802	XM_214061	Huesken	TCAP	8557	UCCUCCUUUGGUCUCACACag	GUGUGAGACCAAAGGAGGA	-2.2	-2.4	-1	1	3	2	-40.5	81.2	15.2	4	II	52.6	61.8	98	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1803	XM_214061	Huesken	TCAP	8557	AGAAACAAUACAAUCCUCCga	GGAGGAUUGUAUUGUUUCU	-3.3	-2.1	0.5	1	4	2	-33.7	74.9	7.5	8	Ia	36.8	73.8	104.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1804	XM_214061	Huesken	TCAP	8557	AAACAAUACAAUCCUCCGAcc	UCGGAGGAUUGUAUUGUUU	-2.4	-0.9	1.5	4	2	3	-34	72.6	6.7	7	II	36.8	58.3	54.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1805	XM_214061	Huesken	TCAP	8557	UCCGACCCUUCUCCCAGGUca	ACCUGGGAGAAGGGUCGGA	-2.2	-2.4	-3.2	0	1	3	-45.5	47.4	1.8	2	II	63.2	45.8	77.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1806	XM_214061	Huesken	TCAP	8557	CCCUUCUCCCAGGUCAUCAgu	UGAUGACCUGGGAGAAGGG	-2.1	-3.3	-3.2	1	-3	3	-42.9	59	-1.1	2	III	57.9	38.5	33.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1807	XM_214061	Huesken	TCAP	8557	GUCCUAGCCGUGUAAGGCCca	GGCCUUACACGGCUAGGAC	-3.3	-2.2	-5	2	2	4	-43.3	43.6	7.4	1	II	63.2	49.2	60	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1808	XM_214061	Huesken	TCAP	8557	AUUGCUGCAUGGAGUCCUCuu	GAGGACUCCAUGCAGCAAU	-2.4	-1.1	0.5	0	4	2	-40.6	58	4.8	5	Ib	52.6	57.4	44.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1809	XM_214061	Huesken	TCAP	8557	GGUGAGCUCCAACUCCAAGuc	CUUGGAGUUGGAGCUCACC	-2.1	-3.3	-3.7	1	1	2	-41.4	47.5	9.7	0	II	57.9	36.3	55.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1810	XM_214061	Huesken	TCAP	8557	UCCAACUCCAAGUCUCAGUgu	ACUGAGACUUGGAGUUGGA	-2.2	-2.4	-0.1	2	0	2	-39.3	75.9	1	7	II	47.4	60.6	88.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1811	XM_214061	Huesken	TCAP	8557	AAGUCUCAGUGUCACAGGGac	CCCUGUGACACUGAGACUU	-3.3	-0.9	2.2	2	4	3	-40.3	65.5	5.4	4	Ib	52.6	56.6	65.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1812	XM_214061	Huesken	TCAP	8557	GUCUCAGUGUCACAGGGACcc	GUCCCUGUGACACUGAGAC	-2.2	-2.2	-1.5	1	1	3	-41.9	47.8	7.5	1	II	57.9	36.8	43	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1813	XM_214061	Huesken	TCAP	8557	AGUGUCACAGGGACCCAAAgu	UUUGGGUCCCUGUGACACU	-0.9	-2.1	-1.5	1	-1	3	-41.2	52	-6.3	4	II	52.6	42	50.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1814	XM_214061	Huesken	TCAP	8557	GUCACAGGGACCCAAAGUUca	AACUUUGGGUCCCUGUGAC	-0.9	-2.2	0.2	1	-1	3	-40	46.4	-6.3	4	III	52.6	37.9	26.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1815	XM_214061	Huesken	TCAP	8557	GCACCUCAAAUUCAGGAACac	GUUCCUGAAUUUGAGGUGC	-2.2	-3.4	-0.9	1	0	2	-36.8	57.8	12.8	2	II	47.4	41.2	23.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1816	XM_214061	Huesken	TCAP	8557	CUCAAAUUCAGGAACACACca	GUGUGUUCCUGAAUUUGAG	-2.2	-2.1	1.9	1	0	2	-34.4	69.6	5.5	5	II	42.1	58	32.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1817	XM_214061	Huesken	TCAP	8557	CCAGGAAUGAACGUUAUUCac	GAAUAACGUUCAUUCCUGG	-2.4	-3.3	-0.2	0	0	2	-34	61.6	7.7	4	II	42.1	52.4	66.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1818	XM_214061	Huesken	TCAP	8557	AUGUGAGCGCAUUUUCCAAau	UUGGAAAAUGCGCUCACAU	-0.9	-1.1	1	2	1	4	-35.8	68.6	3.9	5	II	42.1	45.6	38.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1819	XM_214061	Huesken	TCAP	8557	UGUGAGCGCAUUUUCCAAAuc	UUUGGAAAAUGCGCUCACA	-0.9	-2.1	1	1	0	4	-35.6	68.7	4.3	6	II	42.1	52.4	47.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1820	XM_214061	Huesken	TCAP	8557	CAUUUUCCAAAUCAAAGUUau	AACUUUGAUUUGGAAAAUG	-0.9	-2.1	1.4	-1	-1	2	-28.1	87.9	1.8	5	II	26.3	50.1	50.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1821	XM_214061	Huesken	TCAP	8557	UUCCAAAUCAAAGUUAUUUuc	AAAUAACUUUGAUUUGGAA	-0.9	-0.9	1.4	2	1	2	-27.3	90.4	3.4	8	II	21.1	69.3	70.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1822	XM_214061	Huesken	TCAP	8557	UCCAAAUCAAAGUUAUUUUcc	AAAAUAACUUUGAUUUGGA	-0.9	-2.4	1.4	1	0	2	-27.3	96	3.4	8	II	21.1	61.9	69.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1823	XM_214061	Huesken	TCAP	8557	AAACUCAUAUCGAGGUCGUca	ACGACCUCGAUAUGAGUUU	-2.2	-0.9	-0.9	1	3	2	-35.9	61.1	-8.9	6	II	42.1	53.3	70	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1824	XM_214061	Huesken	TCAP	8557	AGACCAUAGCAGAAACGUAgu	UACGUUUCUGCUAUGGUCU	-1.3	-2.1	0.5	4	0	2	-36.5	49.8	-4	4	II	42.1	43.5	62.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1825	XM_214061	Huesken	TCAP	8557	GAAGACAGAGGGGAAAAGAaa	UCUUUUCCCCUCUGUCUUC	-2.4	-2.4		0	-1	4	-38.2	42	-1.1	4	II	47.4	38.6	35.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1826	XM_214061	Huesken	TCAP	8557	GAAAACAAAGGCUCUCUGGuu	CCAGAGAGCCUUUGUUUUC	-3.3	-2.4	-2.8	0	2	3	-36.5	66.7	0.4	5	II	47.4	54.1	89.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1827	XM_214061	Huesken	TCAP	8557	AAGGCUCUCUGGUUUCAGCuu	GCUGAAACCAGAGAGCCUU	-3.4	-0.9	-1.4	2	4	3	-40.2	72.3	9.7	2	II	52.6	59.3	102	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1828	XM_214061	Huesken	TCAP	8557	UUUCAGCUUCUCCAGGGUGuc	CACCCUGGAGAAGCUGAAA	-2.1	-0.9	1.4	1	4	3	-40.1	58.3	2.8	6	Ib	52.6	64.9	66.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1829	XM_214061	Huesken	TCAP	8557	AGGGUGUCAUGUCAGCCAAuc	UUGGCUGACAUGACACCCU	-0.9	-2.1	0.8	2	-1	3	-41.4	52.8	1.7	4	II	52.6	39.6	65.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1830	XM_214061	Huesken	TCAP	8557	UCGCCAUCACUCAACCAGAau	UCUGGUUGAGUGAUGGCGA	-2.4	-2.4	0.5	2	-1	4	-41	49	-8.7	4	II	52.6	52.5	75.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1831	XM_214061	Huesken	TCAP	8557	UGGAAACCGCGGACGGCUCac	GAGCCGUCCGCGGUUUCCA	-2.4	-2.1	-6.3	1	2	6	-44.8	41.5	7.5	3	Ib	68.4	53.6	70.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1832	XM_214061	Huesken	TCAP	8557	GAAACCGCGGACGGCUCACga	GUGAGCCGUCCGCGGUUUC	-2.2	-2.4	-6.5	0	2	6	-43.7	37.7	7.4	2	II	68.4	40.1	72.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1833	XM_214061	Huesken	TCAP	8557	CGCGGACGGCUCACGAAGAcu	UCUUCGUGAGCCGUCCGCG	-2.4	-2.4	-2	0	-4	5	-44.2	19.5	-10.7	-2	III	68.4	24	35.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1834	XM_214061	Huesken	TCAP	8557	AUCCGCCGCACGAGCUGCAcc	UGCAGCUCGUGCGGCGGAU	-2.1	-1.1	-1.9	2	1	7	-46	32.3	-8.7	2	II	68.4	41.1	33.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1835	XM_214061	Huesken	TCAP	8557	CGAGCUGCACCAGCAUCUCgg	GAGAUGCUGGUGCAGCUCG	-2.4	-2.4	-3.1	-1	0	2	-43.2	37.2	3.1	0	II	63.2	42.5	32.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1836	XM_214061	Huesken	TCAP	8557	CCAGCAUCUCGGCCAUCUUcg	AAGAUGGCCGAGAUGCUGG	-0.9	-3.3	-1.3	0	-2	5	-42	43.9	-3.6	0	III	57.9	34	33.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1837	XM_214061	Huesken	TCAP	8557	GGCCAUCUUCGCCAUCUCCug	GGAGAUGGCGAAGAUGGCC	-3.3	-3.3	-2.4	1	0	4	-43.5	48.4	10.2	0	II	63.2	40.7	72.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1838	XM_214061	Huesken	TCAP	8557	CCAUCUUCGCCAUCUCCUGcg	CAGGAGAUGGCGAAGAUGG	-2.1	-3.3	1.1	1	0	4	-41	57	-4.4	2	II	57.9	47.1	81.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1839	XM_214061	Huesken	TCAP	8557	CGCCCUGCAGGUGGUUGAGag	CUCAACCACCUGCAGGGCG	-2.1	-2.4	-1.2	-1	-1	5	-44.8	36.7	1	-1	II	68.4	27.2	43.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1840	XM_214061	Huesken	TCAP	8557	GAGAGCGCUCUCCUCAGAGgc	CUCUGAGGAGAGCGCUCUC	-2.1	-2.4	-2.5	0	2	4	-43.7	46	2.4	1	II	63.2	43.3	48.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1841	XM_214061	Huesken	TCAP	8557	GCUCUCCUCAGAGGCCUCUac	AGAGGCCUCUGAGGAGAGC	-2.1	-3.4	-2.4	1	-1	4	-45.5	40.8	-4	2	III	63.2	32.5	69.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1842	XM_214061	Huesken	TCAP	8557	ACCUGCGUCUUGAUCUGGAuc	UCCAGAUCAAGACGCAGGU	-2.4	-2.2	1.3	2	1	3	-41	52.6	-4	4	II	52.6	41.1	54.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1843	XM_214061	Huesken	TCAP	8557	CAUAUUGUCCAUCUCCCACag	GUGGGAGAUGGACAAUAUG	-2.2	-2.1	1.4	0	2	3	-37.5	80.3	15.5	5	II	47.4	57	79.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1844	XM_214061	Huesken	TCAP	8557	UCUCCCACAGCUUGCCCCGgu	CGGGGCAAGCUGUGGGAGA	-2.4	-2.4	-0.1	0	4	6	-46.2	52.8	0.7	4	II	68.4	60.8	69.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1845	XM_214061	Huesken	TCAP	8557	CUCCCACAGCUUGCCCCGGuu	CCGGGGCAAGCUGUGGGAG	-3.3	-2.1	-0.4	1	1	7	-47.1	30.5	1	0	II	73.7	39.9	44.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1846	XM_214061	Huesken	TCAP	8557	GCGCACGGGCGCGCGUCCGcg	CGGACGCGCGCCCGUGCGC	-2.4	-3.4	-7	2	1	10	-50.2	12.2	0.4	0	II	89.5	31.4	19.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1847	XM_214061	Huesken	TCAP	8557	CGCGCUCGCGCGUCAGCGAcg	UCGCUGACGCGCGAGCGCG	-2.4	-2.4	-5.8	0	-3	6	-47.1	25.2	-8.1	-2	III	78.9	23.7	14	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1848	XM_214061	Huesken	TCAP	8557	UCUCGUGGAUGACGGGCAGca	CUGCCCGUCAUCCACGAGA	-2.1	-2.4	-0.5	0	3	5	-43.7	40.8	2.4	4	II	63.2	47.3	70.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1849	XM_214061	Huesken	TCAP	8557	AUGACGGGCAGCAGAAACUgc	AGUUUCUGCUGCCCGUCAU	-2.1	-1.1	0	1	1	5	-40.5	52.2	-8.9	6	II	52.6	57.5	66.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1850	XM_214061	Huesken	TCAP	8557	AGCAGAAACUGCUCGAAGUcc	ACUUCGAGCAGUUUCUGCU	-2.2	-2.1	-3.9	2	0	2	-38.2	59.6	-6.3	3	II	47.4	47.1	51.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1851	XM_214061	Huesken	TCAP	8557	AGCACCUCCACCUCCUCGGgc	CCGAGGAGGUGGAGGUGCU	-3.3	-2.1	-0.7	3	3	3	-46.5	60.5	-4.7	4	II	68.4	57.5	58.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1852	XM_214061	Huesken	TCAP	8557	GCCGCAUCUCCGCUGCUUUgc	AAAGCAGCGGAGAUGCGGC	-0.9	-3.4	-2.6	1	-2	5	-43.2	44.4	-1.6	0	III	63.2	28.6	35.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1853	XM_214061	Huesken	TCAP	8557	CGCAUCUCCGCUGCUUUGCuu	GCAAAGCAGCGGAGAUGCG	-3.4	-2.4	-2.6	1	-1	4	-42	59.8	6.1	2	II	63.2	46.4	74.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1854	XM_214061	Huesken	TCAP	8557	UCUCCGCUGCUUUGCUUGUcu	ACAAGCAAAGCAGCGGAGA	-2.2	-2.4	-1.4	1	1	4	-40.3	60.5	-1	4	II	52.6	49	62.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1855	XM_214061	Huesken	TCAP	8557	UAUUAACAUGUAAGAUUUUgu	AAAAUCUUACAUGUUAAUA	-0.9	-1.3	2.6	-1	1	1	-25.7	80.2	-3.9	8	II	15.8	60.6	76.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1856	XM_214061	Huesken	TCAP	8557	UAAGGGUUUUGACCUCAAAug	UUUGAGGUCAAAACCCUUA	-0.9	-1.3	-2.5	1	0	3	-34.2	68.6	-1.4	5	II	36.8	56.6	82.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1857	XM_214061	Huesken	TCAP	8557	ACAUUUAUAGCUUGACUACau	GUAGUCAAGCUAUAAAUGU	-2.2	-2.2	-1.6	0	2	2	-31.7	83.3	8.1	6	Ia	31.6	58.7	88.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1858	XM_214061	Huesken	TCAP	8557	UAUAGCUUGACUACAUAUGaa	CAUAUGUAGUCAAGCUAUA	-2.1	-1.3	-2.2	2	3	2	-32.2	91.5	-1.9	7	Ia	31.6	76.1	101.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1859	XM_214061	Huesken	TCAP	8557	UUGACUACAUAUGAACCUUga	AAGGUUCAUAUGUAGUCAA	-0.9	-0.9	1.4	0	1	2	-32.7	81.4	1.4	6	II	31.6	66.3	85.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1860	XM_214061	Huesken	TCAP	8557	GACGCCUCUUCCUUGAAGUuu	ACUUCAAGGAAGAGGCGUC	-2.2	-2.4	-2.1	1	0	4	-39.6	64.1	-6.3	1	III	52.6	41.2	82.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1861	XM_214061	Huesken	TCAP	8557	GUUUUGGGUCCAUUGCAGGuu	CCUGCAAUGGACCCAAAAC	-3.3	-2.2	-1	0	3	3	-38.6	62.3	0	4	II	52.6	51.5	86.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1862	XM_214061	Huesken	TCAP	8557	GGUAUUGCAAGGAUCUUUCau	GAAAGAUCCUUGCAAUACC	-2.4	-3.3	2.1	0	1	2	-34.9	78	7.1	6	II	42.1	52.9	82.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1863	XM_214061	Huesken	TCAP	8557	AUAUGGGGAUACCAACUUGua	CAAGUUGGUAUCCCCAUAU	-2.1	-1.1	-1.1	1	3	4	-36.1	62.9	2.4	6	Ib	42.1	61.3	62.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1864	XM_214061	Huesken	TCAP	8557	GAGUUAGGCUGUCCCAACAaa	UGUUGGGACAGCCUAACUC	-2.1	-2.4	-6.4	1	-2	3	-40.4	57.1	1.7	3	II	52.6	38	85.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1865	XM_214061	Huesken	TCAP	8557	AUCAGGCAGGUUAUAAUAGau	CUAUUAUAACCUGCCUGAU	-2.1	-1.1	3	2	3	3	-34.1	68.7	2.8	5	II	36.8	58.8	88	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1866	XM_214061	Huesken	TCAP	8557	GGCAGGUUAUAAUAGAUAGug	CUAUCUAUUAUAACCUGCC	-2.1	-3.3	2.8	1	-1	3	-33.3	70.3	2.3	3	II	36.8	42.6	90.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1867	XM_214061	Huesken	TCAP	8557	CAUAGAAACAAUACAAUCCuc	GGAUUGUAUUGUUUCUAUG	-3.3	-2.1	0.7	0	1	2	-30.4	82.7	8.1	6	II	31.6	67.3	93.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1868	XM_214061	Huesken	TCAP	8557	UCCCAGGUCAUCAGUCCUAgc	UAGGACUGAUGACCUGGGA	-1.3	-2.4	-2.2	1	-1	3	-42.2	43.5	-6	5	II	52.6	49	70.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1869	XM_214061	Huesken	TCAP	8557	CCCAGGUCAUCAGUCCUAGcc	CUAGGACUGAUGACCUGGG	-2.1	-3.3	-5.3	0	-1	3	-41.9	45.2	-2	1	II	57.9	38.3	63.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1870	XM_214061	Huesken	TCAP	8557	CAUCAGUCCUAGCCGUGUAag	UACACGGCUAGGACUGAUG	-1.3	-2.1	-0.8	2	-2	4	-40.1	54	1.7	4	II	52.6	37.1	61.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1871	XM_214061	Huesken	TCAP	8557	CACAGUCCCAGAUGAAGUCug	GACUUCAUCUGGGACUGUG	-2.4	-2.1	0.7	-1	0	3	-39.5	56	5.4	3	II	52.6	47.2	82.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1872	XM_214061	Huesken	TCAP	8557	UUCUUCUGCCAUUGCUGCAug	UGCAGCAAUGGCAGAAGAA	-2.1	-0.9	-1.3	1	1	3	-38.9	79.4	1.6	6	II	47.4	59.3	72.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1873	XM_214061	Huesken	TCAP	8557	CUUCUGCCAUUGCUGCAUGga	CAUGCAGCAAUGGCAGAAG	-2.1	-2.1	-1.6	0	1	3	-38.8	57.2	2.7	2	II	52.6	47	79.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1874	XM_214061	Huesken	TCAP	8557	UGCAUGGAGUCCUCUUCUAga	UAGAAGAGGACUCCAUGCA	-1.3	-2.1	0.5	1	-1	2	-39.8	61	-8.5	6	II	47.4	48.1	68.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1875	XM_214061	Huesken	TCAP	8557	GAACUUUCAGAGGCGGUGAgc	UCACCGCCUCUGAAAGUUC	-2.4	-2.4	0.9	2	-1	5	-39.6	56.2	-1.5	5	II	52.6	41.6	45.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1876	XM_214061	Huesken	TCAP	8557	GGCGGUGAGCUCCAACUCCaa	GGAGUUGGAGCUCACCGCC	-3.3	-3.3	-3.7	1	0	5	-45.4	32	7.5	0	II	68.4	42.7	50	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1877	XM_214061	Huesken	TCAP	8557	CUCCAACUCCAAGUCUCAGug	CUGAGACUUGGAGUUGGAG	-2.1	-2.1	-0.1	1	1	2	-39.2	50.9	5.3	2	II	52.6	40.8	81.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1878	XM_214061	Huesken	TCAP	8557	CCAACUCCAAGUCUCAGUGuc	CACUGAGACUUGGAGUUGG	-2.1	-3.3	-0.1	-1	1	2	-39	66.6	5.8	3	II	52.6	47.7	77.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1879	XM_214061	Huesken	TCAP	8557	GGGACCCAAAGUUCAGGGAgc	UCCCUGAACUUUGGGUCCC	-2.4	-3.3	-3.7	0	-2	3	-42.5	50.9	-0.7	0	III	57.9	26.1	53.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1880	XM_214061	Huesken	TCAP	8557	GUUCAGGGAGCUAUCAGGUca	ACCUGAUAGCUCCCUGAAC	-2.2	-2.2	1.2	1	2	3	-40.8	49.4	-0.9	4	III	52.6	43.7	68.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1881	XM_214061	Huesken	TCAP	8557	GGGAGCUAUCAGGUCACCCaa	GGGUGACCUGAUAGCUCCC	-3.3	-3.3	-4.3	1	2	3	-44.4	48.9	12	0	II	63.2	48.5	87.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1882	XM_214061	Huesken	TCAP	8557	GCUAUCAGGUCACCCAAGAaa	UCUUGGGUGACCUGAUAGC	-2.4	-3.4	-4.3	1	-2	3	-40.8	47.9	-3.7	3	II	52.6	32.8	45.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1883	XM_214061	Huesken	TCAP	8557	AGGUCACCCAAGAAAGAGCaa	GCUCUUUCUUGGGUGACCU	-3.4	-2.1	-4.3	2	2	3	-40.2	57.5	7.1	3	II	52.6	54.4	95.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1884	XM_214061	Huesken	TCAP	8557	GAACACACCAAAGCCAGGAau	UCCUGGCUUUGGUGUGUUC	-2.4	-2.4	-0.1	2	0	3	-40	46.7	1.3	5	II	52.6	43.3	66.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1885	XM_214061	Huesken	TCAP	8557	ACACCAAAGCCAGGAAUGAac	UCAUUCCUGGCUUUGGUGU	-2.4	-2.2	-0.1	2	0	3	-38.9	36.5	-6.1	5	II	47.4	38.5	52.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1886	XM_214061	Huesken	TCAP	8557	GUAUGUGAGCGCAUUUUCCaa	GGAAAAUGCGCUCACAUAC	-3.3	-2.2	0.6	1	3	4	-36.3	68.3	4.8	5	II	47.4	57.5	86.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1887	XM_214061	Huesken	TCAP	8557	AGCGCAUUUUCCAAAUCAAag	UUGAUUUGGAAAAUGCGCU	-0.9	-2.1	1.5	2	-1	4	-33.3	59.1	-11	3	II	36.8	39.4	68.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1888	XM_214061	Huesken	TCAP	8557	CCAUAGCAGAAACGUAGUGuc	CACUACGUUUCUGCUAUGG	-2.1	-3.3	0.5	-1	0	2	-36.2	47.4	5.4	4	II	47.4	40.7	58	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1889	XM_214061	Huesken	TCAP	8557	AGCAGAAACGUAGUGUCAGug	CUGACACUACGUUUCUGCU	-2.1	-2.1	0.8	2	3	2	-37.2	52.8	2.3	4	Ib	47.4	51.2	99.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1890	XM_214061	Huesken	TCAP	8557	AACGUAGUGUCAGUGAGAAca	UUCUCACUGACACUACGUU	-0.9	-0.9	0.9	2	1	2	-36.3	54.1	-3.8	5	II	42.1	40.9	72.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1891	XM_214061	Huesken	TCAP	8557	CGUAGUGUCAGUGAGAACAga	UGUUCUCACUGACACUACG	-2.1	-2.4	-0.2	0	-3	2	-37.5	61.4	-2.7	4	III	47.4	44.9	68.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1892	XM_214061	Huesken	TCAP	8557	CAGAGUGAAGACAGAGGGGaa	CCCCUCUGUCUUCACUCUG	-3.3	-2.1	1.9	-2	1	4	-41.6	40.8	-4.6	2	II	57.9	47.1	87.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1893	XM_214061	Huesken	TCAP	8557	AAGGAAAACAAAGGCUCUCug	GAGAGCCUUUGUUUUCCUU	-2.4	-0.9	-3.4	1	3	3	-35.3	55.9	12.4	5	Ia	42.1	62.2	106.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1894	XM_214061	Huesken	TCAP	8557	ACAAAGGCUCUCUGGUUUCag	GAAACCAGAGAGCCUUUGU	-2.4	-2.2	-1.3	0	2	3	-37.8	57	7.8	6	Ib	47.4	56.6	86	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1895	XM_214061	Huesken	TCAP	8557	UCAGCCAAUCGCCAUCACUca	AGUGAUGGCGAUUGGCUGA	-2.1	-2.4	-1.9	0	1	4	-40.9	57.6	-3.9	4	II	52.6	59.5	85.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1896	XM_214061	Huesken	TCAP	8557	UUCUCUAUCCGCCGCACGAgc	UCGUGCGGCGGAUAGAGAA	-2.4	-0.9	-0.8	0	1	7	-42	63.8	-3.7	5	II	57.9	56.8	87.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1897	XM_214061	Huesken	TCAP	8557	UCUAUCCGCCGCACGAGCUgc	AGCUCGUGCGGCGGAUAGA	-2.1	-2.4	-1.9	1	2	7	-44.2	54.7	-8.9	4	II	63.2	54.7	79.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1898	XM_214061	Huesken	TCAP	8557	CCGCCGCACGAGCUGCACCag	GGUGCAGCUCGUGCGGCGG	-3.3	-3.3	-2.3	1	0	7	-48	32.4	12.4	-2	II	78.9	40.2	88.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1899	XM_214061	Huesken	TCAP	8557	UCUCGGCCAUCUUCGCCAUcu	AUGGCGAAGAUGGCCGAGA	-1.1	-2.4	-4.4	1	1	5	-42.6	51.4	-3.3	2	II	57.9	43	78.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1900	XM_214061	Huesken	TCAP	8557	GCGCCUUCUCGUCGGCCUUcu	AAGGCCGACGAGAAGGCGC	-0.9	-3.4	-5	1	-2	5	-44.8	39.2	1.5	-1	III	68.4	27.5	63.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1901	XM_214061	Huesken	TCAP	8557	CGUCGGCCUUCUCCGCCCUgg	AGGGCGGAGAAGGCCGACG	-2.1	-2.4	-4.1	0	-1	6	-47.1	31.1	-2.9	-1	III	73.7	31.3	23.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1902	XM_214061	Huesken	TCAP	8557	CGGCCUUCUCCGCCCUGGGgc	CCCAGGGCGGAGAAGGCCG	-3.3	-2.4	-4.1	1	0	6	-48.8	37	-2	-1	II	78.9	40	65.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1903	XM_214061	Huesken	TCAP	8557	GCGGGGCUCGGCGCCGCCCgc	GGGCGGCGCCGAGCCCCGC	-3.3	-3.4	-7.4	1	1	11	-54.2	9.4	5.1	-2	II	94.7	34.9	74.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1904	XM_214061	Huesken	TCAP	8557	GCCGCCCGCGCCCUGCAGGug	CCUGCAGGGCGCGGGCGGC	-3.3	-3.4	-6.5	1	1	13	-52.4	22.1	0	-2	II	89.5	28.8	60.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1905	XM_214061	Huesken	TCAP	8557	GGCCUCUACCUGCGUCUUGau	CAAGACGCAGGUAGAGGCC	-2.1	-3.3	-1	2	-1	4	-43.1	44	2.4	1	II	63.2	34.9	73.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1906	XM_214061	Huesken	TCAP	8557	CUCUACCUGCGUCUUGAUCug	GAUCAAGACGCAGGUAGAG	-2.4	-2.1	0.6	0	0	3	-39	68.7	15.9	3	II	52.6	44.5	72	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1907	XM_214061	Huesken	TCAP	8557	UGGAUCAGCAUAUUGUCCAuc	UGGACAAUAUGCUGAUCCA	-2.1	-2.1	-0.9	1	1	2	-37.5	76.8	-1.4	7	II	42.1	65	91.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1908	XM_214061	Huesken	TCAP	8557	UAUUGUCCAUCUCCCACAGcu	CUGUGGGAGAUGGACAAUA	-2.1	-1.3	0.6	0	4	3	-38.5	76.3	3.1	6	Ia	47.4	62.5	82.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1909	XM_214061	Huesken	TCAP	8557	CCAUCUCCCACAGCUUGCCcc	GGCAAGCUGUGGGAGAUGG	-3.3	-3.3	0.7	0	1	3	-43.7	50.4	3.1	2	II	63.2	47.4	81	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1910	XM_214061	Huesken	TCAP	8557	CCCGGUUGCGCACGGGCGCgc	GCGCCCGUGCGCAACCGGG	-3.4	-3.3	-6.1	0	0	7	-49.2	19.4	5.5	-1	II	84.2	37.3	55.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1911	XM_214061	Huesken	TCAP	8557	UCAGCGACGCGAUGUCCUCgc	GAGGACAUCGCGUCGCUGA	-2.4	-2.4	-2.2	0	3	4	-43.2	45.1	7.4	3	II	63.2	58.6	77.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1912	XM_214061	Huesken	TCAP	8557	CGUGGAUGACGGGCAGCAGaa	CUGCUGCCCGUCAUCCACG	-2.1	-2.4	0.6	0	0	5	-44.4	29.8	-2	1	II	68.4	32.2	39.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1913	XM_214061	Huesken	TCAP	8557	GUGGAUGACGGGCAGCAGAaa	UCUGCUGCCCGUCAUCCAC	-2.4	-2.2	1.9	1	-2	5	-44.4	36	1.4	2	III	63.2	37	35.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1914	XM_214061	Huesken	TCAP	8557	CAGCAGAAACUGCUCGAAGuc	CUUCGAGCAGUUUCUGCUG	-2.1	-2.1	-4.6	0	0	2	-38.1	48.8	5.4	2	II	52.6	46.5	59.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1915	XM_214061	Huesken	TCAP	8557	UCCGGCUCCAGCACCUCCAcc	UGGAGGUGCUGGAGCCGGA	-2.1	-2.4	-3.1	2	0	5	-47.7	47.3	-8.7	3	II	68.4	54.8	69.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1916	XM_214061	Huesken	TCAP	8557	UCCGCCAGCUCCACUGCGUcc	ACGCAGUGGAGCUGGCGGA	-2.2	-2.4	-2.5	1	1	5	-46.7	42.2	-11.3	2	II	68.4	48.9	76.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1917	XM_214061	Huesken	TCAP	8557	CCGCCAGCUCCACUGCGUCca	GACGCAGUGGAGCUGGCGG	-2.4	-3.3	-2.5	0	0	5	-46.7	29.7	7.8	-1	II	73.7	35.8	65.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1918	XM_214061	Huesken	TCAP	8557	GGCCGCAUCUCCGCUGCUUug	AAGCAGCGGAGAUGCGGCC	-0.9	-3.3	-2.6	2	-2	6	-45.6	31.1	-8.7	-1	III	68.4	25.4	42.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1919	XM_214061	Huesken	TCAP	8557	GCUUUGCUUGUCUGCACGAca	UCGUGCAGACAAGCAAAGC	-2.4	-3.4	-2.1	-1	-1	2	-39.2	48.5	-6.1	2	III	52.6	31.4	67.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1920	XM_214061	Huesken	TCAP	8557	GCUUGUCUGCACGACACUCag	GAGUGUCGUGCAGACAAGC	-2.4	-3.4	-3.8	1	1	2	-40.8	48.3	7.4	0	II	57.9	41.1	64.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1921	XM_214061	Huesken	TCAP	8557	GACCGAGCUCGGGCCGAGUcu	ACUCGGCCCGAGCUCGGUC	-2.2	-2.4	-3.1	1	-1	7	-47.5	23.6	-4	0	III	73.7	28.8	61.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1922	XM_214061	Huesken	TCAP	8557	GUCUUCAAAACUUCCGCCGcu	CGGCGGAAGUUUUGAAGAC	-2.4	-2.2	-2.5	0	2	6	-37.2	72	0.7	4	II	52.6	56.3	94.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1923	XM_214061	Huesken	TCAP	8557	AAAACUUCCGCCGCUGUUCca	GAACAGCGGCGGAAGUUUU	-2.4	-0.9	-2.5	3	3	7	-38.2	70.4	2.7	6	Ia	52.6	67.2	84.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1924	NM_017346	Huesken	Cacnb1	782	CUGCCUCUCAGCGGAUGUAga	UACAUCCGCUGAGAGGCAG	-1.3	-2.1	-5.2	0	-3	4	-42.3	42.7	-8.1	0	III	57.9	30.8	39.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1925	NM_017346	Huesken	Cacnb1	782	CAGCCCUCCAGCUCAUUCUua	AGAAUGAGCUGGAGGGCUG	-2.1	-2.1	-2.9	2	-2	4	-42.7	64.8	-8.3	2	III	57.9	48.7	75.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1926	NM_017346	Huesken	Cacnb1	782	AGCCCUCCAGCUCAUUCUUau	AAGAAUGAGCUGGAGGGCU	-0.9	-2.1	-2.2	2	0	4	-41.5	56.8	-0.9	1	II	52.6	40.1	54.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1927	NM_017346	Huesken	Cacnb1	782	UUGCGCCCCAGAACCGGCCca	GGCCGGUUCUGGGGCGCAA	-3.3	-0.9	-4.4	2	4	7	-47.5	45.1	4.8	3	II	73.7	67.7	79.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1928	NM_017346	Huesken	Cacnb1	782	GGCCCACCACCCUCCGCACag	GUGCGGAGGGUGGUGGGCC	-2.2	-3.3	-0.5	1	0	5	-49.7	29.1	2.7	-1	II	78.9	25.2	52.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1929	NM_017346	Huesken	Cacnb1	782	CCUCCUCUUCCCAGGAGCCcu	GGCUCCUGGGAAGAGGAGG	-3.3	-3.3	-6.7	-1	1	3	-46.3	39.1	-1.9	-1	II	68.4	41.2	46.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1930	NM_017346	Huesken	Cacnb1	782	GAGUCUCCUGGCUCCGUGUag	ACACGGAGCCAGGAGACUC	-2.2	-2.4	-1.8	0	-1	3	-44.5	56.8	-6.3	1	III	63.2	38.4	48.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1931	NM_017346	Huesken	Cacnb1	782	AGUCUCCUGGCUCCGUGUAga	UACACGGAGCCAGGAGACU	-1.3	-2.1	-1.7	3	0	3	-43.4	52.7	-0.7	2	II	57.9	35.6	54.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1932	NM_017346	Huesken	Cacnb1	782	CCGUGUAGACAGAGUUUCGgc	CGAAACUCUGUCUACACGG	-2.4	-3.3	-0.3	-2	-1	3	-37.7	52.6	-2.3	3	II	52.6	44.5	44	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1933	NM_017346	Huesken	Cacnb1	782	UCAAAGGUGUCUUGGCGGGau	CCCGCCAAGACACCUUUGA	-3.3	-2.4	0.1	0	4	6	-41.4	51.7	3.4	6	Ib	57.9	58.4	57.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1934	NM_017346	Huesken	Cacnb1	782	AGGUGUCUUGGCGGGAUAGcg	CUAUCCCGCCAAGACACCU	-2.1	-2.1	2.2	0	1	6	-42	49.4	-2.4	3	II	57.9	43.2	70.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1935	NM_017346	Huesken	Cacnb1	782	GGCCAGGUGGGUGGUUGCUgg	AGCAACCACCCACCUGGCC	-2.1	-3.3	-1.1	1	-1	4	-46.7	26.9	1.8	0	III	68.4	24.5	31.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1936	NM_017346	Huesken	Cacnb1	782	GGGGCUGGCCCAGCUCCCCgg	GGGGAGCUGGGCCAGCCCC	-3.3	-3.3	-4.6	1	1	5	-52.8	21.5	5.1	-1	II	84.2	39.2	19.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1937	NM_017346	Huesken	Cacnb1	782	GGUAGCCAUGGUGCGGUUCag	GAACCGCACCAUGGCUACC	-2.4	-3.3	-0.9	0	0	4	-43.1	47.5	10.4	2	II	63.2	36.4	49	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1938	NM_017346	Huesken	Cacnb1	782	UCAGCAGCGGAUUGGGUGGcg	CCACCCAAUCCGCUGCUGA	-3.3	-2.4	2.1	0	3	4	-44	51	5.3	5	II	63.2	56.9	81.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1939	NM_017346	Huesken	Cacnb1	782	CUUCCAGUAGGCUUCCAAGua	CUUGGAAGCCUACUGGAAG	-2.1	-2.1	-1	0	1	3	-39	63.2	-2	2	II	52.6	47	60.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1940	NM_017346	Huesken	Cacnb1	782	AGGCAUCUUCCAAUUGGUUcu	AACCAAUUGGAAGAUGCCU	-0.9	-2.1	-1.1	2	1	3	-36.6	57.8	-3.9	2	II	42.1	44.9	50	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1941	NM_017346	Huesken	Cacnb1	782	CAAUUGGUUCUCGUCCAGGau	CCUGGACGAGAACCAAUUG	-3.3	-2.1	-1	-1	2	2	-38.2	57.8	-2	4	II	52.6	57.1	80.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1942	NM_017346	Huesken	Cacnb1	782	UGAUGAGCCUCUGCAGUACcu	GUACUGCAGAGGCUCAUCA	-2.2	-2.1	-0.4	1	2	3	-40.9	58.1	8.1	7	Ib	52.6	55.5	73.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1943	NM_017346	Huesken	Cacnb1	782	AGCGAGGUUUUAGAGAGCUgg	AGCUCUCUAAAACCUCGCU	-2.1	-2.1	0.4	1	1	3	-38.5	43.5	-1.3	4	II	47.4	49.4	56.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1944	NM_017346	Huesken	Cacnb1	782	GAUCCGCUCGAUUUCACUCug	GAGUGAAAUCGAGCGGAUC	-2.4	-2.4	0.2	2	3	4	-38.4	70.4	15.1	2	II	52.6	50.8	84.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1945	NM_017346	Huesken	Cacnb1	782	AUUUCACUCUGUACCUCAGcc	CUGAGGUACAGAGUGAAAU	-2.1	-1.1	-0.8	2	4	2	-36	78.7	0.4	5	Ia	42.1	55.1	59.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1946	NM_017346	Huesken	Cacnb1	782	CACUCUGUACCUCAGCCAGgc	CUGGCUGAGGUACAGAGUG	-2.1	-2.1	-1.3	-1	0	3	-41.6	60.1	1.1	1	II	57.9	44	34.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1947	NM_017346	Huesken	Cacnb1	782	GCGAGUGUUGGAGCGCUCGau	CGAGCGCUCCAACACUCGC	-2.4	-3.4	-1.9	0	0	4	-43.7	37.9	0	1	II	68.4	43.5	15.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1948	NM_017346	Huesken	Cacnb1	782	AUAAUGUGUUUGCUGGGGUug	ACCCCAGCAAACACAUUAU	-2.2	-1.1	3.9	2	4	4	-36.6	70.3	0.8	7	II	42.1	61.1	63.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1949	NM_017346	Huesken	Cacnb1	782	UUGAGCGAUGGUCCCACCAgg	UGGUGGGACCAUCGCUCAA	-2.1	-0.9	-4	0	1	3	-43.1	58.4	1.7	4	II	57.9	61.8	71.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1950	NM_017346	Huesken	Cacnb1	782	GGGGCACGUGCUCUGUCGAcu	UCGACAGAGCACGUGCCCC	-2.4	-3.3	-0.6	0	-1	5	-45.8	33.9	1.7	-1	III	68.4	22	39.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1951	NM_017346	Huesken	Cacnb1	782	UUCUGCUUCUGUUUGGCACug	GUGCCAAACAGAAGCAGAA	-2.2	-0.9	-0.6	2	4	3	-37.6	89.7	12.8	6	Ib	47.4	66.9	82.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1952	NM_017346	Huesken	Cacnb1	782	UGCUGGAGCUGAGGCGGUUuu	AACCGCCUCAGCUCCAGCA	-0.9	-2.1	-1.4	0	0	5	-45.1	35.7	-4	3	II	63.2	42.7	46.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1953	NM_017346	Huesken	Cacnb1	782	GAGCUGAGGCGGUUUUGGCgc	GCCAAAACCGCCUCAGCUC	-3.4	-2.4	-0.3	2	3	5	-42.7	51.1	9.7	2	II	63.2	45.7	54.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1954	NM_017346	Huesken	Cacnb1	782	AGCAGGCGAAGGCUGUCCAgu	UGGACAGCCUUCGCCUGCU	-2.1	-2.1	-0.5	1	1	4	-45.1	45.6	1	3	II	63.2	40.1	39.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1955	NM_017346	Huesken	Cacnb1	782	GACAGGGCUGGGGAUGAAAcc	UUUCAUCCCCAGCCCUGUC	-0.9	-2.4	1.4	0	-3	4	-42.7	35.1	-3.8	2	III	57.9	27.2	16.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1956	NM_017346	Huesken	Cacnb1	782	UCCUUCACCAGCCUCCCGAuc	UCGGGAGGCUGGUGAAGGA	-2.4	-2.4	-0.9	1	1	4	-45.5	61.6	-1.4	6	II	63.2	54.6	73.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1957	NM_017346	Huesken	Cacnb1	782	CAGCCUCCCGAUCCACCAGuc	CUGGUGGAUCGGGAGGCUG	-2.1	-2.1	-1	1	0	4	-45.4	46.7	5.7	-1	II	68.4	40.7	40.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1958	NM_017346	Huesken	Cacnb1	782	UUCUCCUUGAUGUGCAGGAag	UCCUGCACAUCAAGGAGAA	-2.4	-0.9	-3.9	1	1	2	-39.4	73.7	-3.8	6	II	47.4	59.7	94	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1959	NM_017346	Huesken	Cacnb1	782	AUGUGCAGGAAGUCCUUGGgc	CCAAGGACUUCCUGCACAU	-3.3	-1.1	-2.4	2	3	2	-40.1	70.1	2.3	6	Ib	52.6	64.7	63.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1960	NM_017346	Huesken	Cacnb1	782	ACUGGCACCUCAUCUCCUGga	CAGGAGAUGAGGUGCCAGU	-2.1	-2.2	0	2	3	3	-42.8	51	-2.4	3	II	57.9	52.6	83.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1961	NM_017346	Huesken	Cacnb1	782	ACGGAUUGUAGCCAACAUUug	AAUGUUGGCUACAAUCCGU	-0.9	-2.2	-1	2	-1	3	-36	59.5	-1.2	4	II	42.1	52.6	90.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1962	NM_017346	Huesken	Cacnb1	782	CUUUCUCGAGCUGGGCUAAgg	UUAGCCCAGCUCGAGAAAG	-0.9	-2.1	0.4	-2	-3	4	-39.6	53.1	-5.1	4	II	52.6	28.6	63.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1963	NM_017346	Huesken	Cacnb1	782	UUCUCGAGCUGGGCUAAGGcc	CCUUAGCCCAGCUCGAGAA	-3.3	-0.9	0.4	1	3	4	-42	62.5	0	5	Ib	57.9	64.1	76.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1964	NM_017346	Huesken	Cacnb1	782	GACACGUCGGAGUCUGACGgc	CGUCAGACUCCGACGUGUC	-2.4	-2.4	-3.2	2	1	3	-41.9	57.9	2.3	1	II	63.2	49.6	77	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1965	NM_017346	Huesken	Cacnb1	782	CGGAGUCUGACGGCCGGCUcg	AGCCGGCCGUCAGACUCCG	-2.1	-2.4	0	0	-2	8	-47.2	30.7	-8.3	1	III	73.7	35.2	44.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1966	NM_017346	Huesken	Cacnb1	782	GGCUCGUGUAGGACUCUGCug	GCAGAGUCCUACACGAGCC	-3.4	-3.3	1.2	1	0	3	-43.5	54.7	4.8	3	II	63.2	44.3	79.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1967	NM_017346	Huesken	Cacnb1	782	GACCUUUUGAACCGCCCUUuc	AAGGGCGGUUCAAAAGGUC	-0.9	-2.4	0	2	-1	6	-39	58.2	-1.6	4	II	52.6	42.2	57.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1968	NM_017346	Huesken	Cacnb1	782	CUGUAUUUGCCCUGUGGGCug	GCCCACAGGGCAAAUACAG	-3.4	-2.1	-6	0	1	4	-41.2	58.8	3.4	2	II	57.9	50.7	75.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1969	NM_017346	Huesken	Cacnb1	782	AGACCUCCAUAGGGAUCUCuu	GAGAUCCCUAUGGAGGUCU	-2.4	-2.1	-2.7	1	3	3	-41.4	48.8	9.7	2	II	52.6	45.3	71.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1970	NM_012864	Huesken	Mmp7	4316	UGUCGUCCUUUGUAAGACUga	AGUCUUACAAAGGACGACA	-2.1	-2.1	-4.1	1	1	2	-36.2	64.7	-4	3	II	42.1	57.1	98.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1971	NM_012864	Huesken	Mmp7	4316	UCCUUUGUAAGACUGAAGUcu	ACUUCAGUCUUACAAAGGA	-2.2	-2.4	0.3	0	1	2	-34.6	85	0.8	7	II	36.8	62	111.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1972	NM_012864	Huesken	Mmp7	4316	CCUUUGUAAGACUGAAGUCuu	GACUUCAGUCUUACAAAGG	-2.4	-3.3	-1.9	-1	0	2	-34.6	66.1	5.4	3	II	42.1	47.4	92.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1973	NM_012864	Huesken	Mmp7	4316	AAGACUGAAGUCUUCUGAAug	UUCAGAAGACUUCAGUCUU	-0.9	-0.9	-3.6	1	1	1	-34.7	73.8	-3.8	4	II	36.8	51.2	92.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1974	NM_012864	Huesken	Mmp7	4316	ACUGAAGUCUUCUGAAUGAuc	UCAUUCAGAAGACUUCAGU	-2.4	-2.2	1	1	0	1	-34.9	57.4	-3.4	6	II	36.8	43.6	54.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1975	NM_012864	Huesken	Mmp7	4316	UGAAUGAUCUCCUUGAUAGgu	CUAUCAAGGAGAUCAUUCA	-2.1	-2.1	-0.2	1	3	2	-34.3	87.2	-2.4	8	Ia	36.8	69.5	115.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1976	NM_012864	Huesken	Mmp7	4316	UGAUCUCCUUGAUAGGUAGgg	CUACCUAUCAAGGAGAUCA	-2.1	-2.1	-1.9	0	2	2	-36.7	77.8	0	5	Ib	42.1	58.9	114.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1977	NM_012864	Huesken	Mmp7	4316	AUCUCCUUGAUAGGUAGGGua	CCCUACCUAUCAAGGAGAU	-3.3	-1.1	-1.9	2	4	3	-38.8	66.3	0	5	Ib	47.4	60.8	102.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1978	NM_012864	Huesken	Mmp7	4316	AUAGGUAGGGUACAUCACAga	UGUGAUGUACCCUACCUAU	-2.1	-1.1	1.1	2	1	3	-37.7	53.7	-1.4	5	II	42.1	60.6	107.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1979	NM_012864	Huesken	Mmp7	4316	AGGUAGGGUACAUCACAGAac	UCUGUGAUGUACCCUACCU	-2.4	-2.1	1.1	1	-1	3	-39.8	50.9	-3.4	6	II	47.4	46.1	55.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1980	NM_012864	Huesken	Mmp7	4316	GUAGGGUACAUCACAGAACug	GUUCUGUGAUGUACCCUAC	-2.2	-2.2	1.9	2	1	3	-37.5	53.2	2.5	4	II	47.4	55.1	104.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1981	NM_012864	Huesken	Mmp7	4316	UAGGGUACAUCACAGAACUgg	AGUUCUGUGAUGUACCCUA	-2.1	-1.3	2.2	0	1	3	-37.4	65.1	-3.9	5	II	42.1	67.1	116.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1982	NM_012864	Huesken	Mmp7	4316	UCACAGAACUGGGAACAGAag	UCUGUUCCCAGUUCUGUGA	-2.4	-2.4	-0.3	2	0	3	-39.3	44	-1.1	6	II	47.4	51.2	99.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1983	NM_012864	Huesken	Mmp7	4316	GAACUGGGAACAGAAGAGUga	ACUCUUCUGUUCCCAGUUC	-2.2	-2.4	-0.3	1	0	3	-38.1	42.2	-6.3	5	III	47.4	43.4	81.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1984	NM_012864	Huesken	Mmp7	4316	CAGAAGAGUGACCCAGACCca	GGUCUGGGUCACUCUUCUG	-3.3	-2.1	-1.4	-1	0	3	-41.7	50.3	10.5	2	II	57.9	56.5	73.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1985	NM_012864	Huesken	Mmp7	4316	AAGAGUGACCCAGACCCAGag	CUGGGUCUGGGUCACUCUU	-2.1	-0.9	-1.2	2	3	3	-42.6	43.6	-2.4	3	Ib	57.9	57.1	87.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1986	NM_012864	Huesken	Mmp7	4316	GUGACCCAGACCCAGAGAGug	CUCUCUGGGUCUGGGUCAC	-2.1	-2.2	-0.4	1	1	3	-44.1	46.1	-2.3	2	II	63.2	40.5	73.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1987	NM_012864	Huesken	Mmp7	4316	UGACCCAGACCCAGAGAGUgg	ACUCUCUGGGUCUGGGUCA	-2.2	-2.1	-1	0	1	3	-44.1	42.7	-11.3	3	II	57.9	49.6	61.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1988	NM_012864	Huesken	Mmp7	4316	CCCAGACCCAGAGAGUGGCca	GCCACUCUCUGGGUCUGGG	-3.4	-3.3	-1.5	0	0	3	-46.2	32.8	5.4	0	II	68.4	37.7	63.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1989	NM_012864	Huesken	Mmp7	4316	CCAGACCCAGAGAGUGGCCaa	GGCCACUCUCUGGGUCUGG	-3.3	-3.3	-4.3	-2	1	4	-46.2	30.1	7.8	0	II	68.4	39.4	41.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1990	NM_012864	Huesken	Mmp7	4316	GGCCAAGUUCAUGAGUGGCaa	GCCACUCAUGAACUUGGCC	-3.4	-3.3	-3.3	1	1	4	-41.4	43.5	15.4	0	II	57.9	36.8	62.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1991	NM_012864	Huesken	Mmp7	4316	UCAUGAGUGGCAACAAACAgg	UGUUUGUUGCCACUCAUGA	-2.1	-2.4	1.5	1	0	3	-36.6	53.8	-8.7	6	II	42.1	56.4	104.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1992	NM_012864	Huesken	Mmp7	4316	GAGUGGCAACAAACAGGAAgu	UUCCUGUUUGUUGCCACUC	-0.9	-2.4	1.5	0	-2	3	-37.6	41.6	-4	2	III	47.4	25.9	37.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1993	NM_012864	Huesken	Mmp7	4316	GGCAACAAACAGGAAGUUCac	GAACUUCCUGUUUGUUGCC	-2.4	-3.3	-1	0	-1	3	-36.4	52.7	12.4	3	II	47.4	40.7	53.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1994	NM_012864	Huesken	Mmp7	4316	GCAACAAACAGGAAGUUCAcg	UGAACUUCCUGUUUGUUGC	-2.1	-3.4	-1.2	1	-2	2	-35.2	59	-6.3	4	II	42.1	42.2	33.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1995	NM_012864	Huesken	Mmp7	4316	AAACAGGAAGUUCACGCCUga	AGGCGUGAACUUCCUGUUU	-2.1	-0.9	-0.5	2	3	4	-37.9	52.6	4.2	6	II	47.4	61	91.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1996	NM_012864	Huesken	Mmp7	4316	AGGAAGUUCACGCCUGAGUcc	ACUCAGGCGUGAACUUCCU	-2.2	-2.1	0.5	3	0	4	-40.6	60.2	-1.2	6	II	52.6	52.6	73.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1997	NM_012864	Huesken	Mmp7	4316	GAAGUUCACGCCUGAGUCCuc	GGACUCAGGCGUGAACUUC	-3.3	-2.4	0.5	0	2	4	-40.9	51.6	2.7	3	II	57.9	50.4	70.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1998	NM_012864	Huesken	Mmp7	4316	UUCACGCCUGAGUCCUCACca	GUGAGGACUCAGGCGUGAA	-2.2	-0.9	-0.6	0	3	4	-42.1	67.3	9.7	4	II	57.9	62.6	89.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC1999	NM_012864	Huesken	Mmp7	4316	UCACGCCUGAGUCCUCACCau	GGUGAGGACUCAGGCGUGA	-3.3	-2.4	-0.6	2	3	4	-44.5	57.9	12.8	4	II	63.2	62.5	94.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2000	NM_012864	Huesken	Mmp7	4316	CACGCCUGAGUCCUCACCAuc	UGGUGAGGACUCAGGCGUG	-2.1	-2.1	-0.6	0	-1	4	-44.2	48.6	-3.4	1	III	63.2	43.5	69.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2001	NM_012864	Huesken	Mmp7	4316	ACGCCUGAGUCCUCACCAUcc	AUGGUGAGGACUCAGGCGU	-1.1	-2.2	-0.6	3	0	4	-43.2	43.1	-8.7	2	II	57.9	38.1	65.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2002	NM_012864	Huesken	Mmp7	4316	CGCCUGAGUCCUCACCAUCcg	GAUGGUGAGGACUCAGGCG	-2.4	-2.4	-0.6	0	-2	4	-43.4	42.7	8.5	1	II	63.2	43.3	61.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2003	NM_012864	Huesken	Mmp7	4316	GAGUCCUCACCAUCCGUCCag	GGACGGAUGGUGAGGACUC	-3.3	-2.4	0.8	1	1	3	-43.7	62.2	5.1	3	II	63.2	51.8	81.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2004	NM_012864	Huesken	Mmp7	4316	AGUCCUCACCAUCCGUCCAgu	UGGACGGAUGGUGAGGACU	-2.1	-2.1	0.9	3	1	3	-43.4	58.5	4	2	II	57.9	42.9	52.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2005	NM_012864	Huesken	Mmp7	4316	UCCUCACCAUCCGUCCAGUac	ACUGGACGGAUGGUGAGGA	-2.2	-2.4	0.3	0	1	3	-43.4	52.6	-6.3	3	II	57.9	44.4	46.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2006	NM_012864	Huesken	Mmp7	4316	CCUCACCAUCCGUCCAGUAcu	UACUGGACGGAUGGUGAGG	-1.3	-3.3	-0.8	0	-3	3	-42.3	39.7	-5.4	1	III	57.9	26.6	32.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2007	NM_012864	Huesken	Mmp7	4316	UCACCAUCCGUCCAGUACUca	AGUACUGGACGGAUGGUGA	-2.1	-2.4	-1	3	1	3	-41.2	58.6	-3.9	4	II	52.6	61.3	90.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2008	NM_012864	Huesken	Mmp7	4316	ACCAUCCGUCCAGUACUCAuc	UGAGUACUGGACGGAUGGU	-2.1	-2.2	0.7	1	0	3	-41.2	49.4	-3.8	5	II	52.6	40.6	63.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2009	NM_012864	Huesken	Mmp7	4316	CCAUCCGUCCAGUACUCAUcc	AUGAGUACUGGACGGAUGG	-1.1	-3.3	0.7	0	-2	3	-40.1	58.2	-3.7	3	III	52.6	35.8	41.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2010	NM_012864	Huesken	Mmp7	4316	CAUCCGUCCAGUACUCAUCcu	GAUGAGUACUGGACGGAUG	-2.4	-2.1	0.7	2	0	3	-39.2	68.7	5.8	4	II	52.6	56.8	87.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2011	NM_012864	Huesken	Mmp7	4316	CCGUCCAGUACUCAUCCUUgu	AAGGAUGAGUACUGGACGG	-0.9	-3.3	0.6	-1	-3	3	-39.9	56.1	-2.9	3	III	52.6	38.8	75.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2012	NM_012864	Huesken	Mmp7	4316	CAUCCUUGUCAAAGUGAGCau	GCUCACUUUGACAAGGAUG	-3.4	-2.1	0.7	0	1	2	-36.8	62.2	5.1	3	II	47.4	52.8	101.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2013	NM_012864	Huesken	Mmp7	4316	UCAAAGUGAGCAUCUCCGCcg	GCGGAGAUGCUCACUUUGA	-3.4	-2.4	-1.8	1	4	4	-39.8	60.7	7.8	6	Ia	52.6	69.3	108.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2014	NM_012864	Huesken	Mmp7	4316	AAAGUGAGCAUCUCCGCCGag	CGGCGGAGAUGCUCACUUU	-2.4	-0.9	-2.1	2	5	6	-41	58.7	-2.4	5	Ia	57.9	74	118.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2015	NM_012864	Huesken	Mmp7	4316	GUGAGCAUCUCCGCCGAGGcc	CCUCGGCGGAGAUGCUCAC	-3.3	-2.2	-2.1	1	1	6	-44.9	41.5	-4.7	1	II	68.4	46.3	72.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2016	NM_012864	Huesken	Mmp7	4316	UGAGCAUCUCCGCCGAGGCcu	GCCUCGGCGGAGAUGCUCA	-3.4	-2.1	-2.4	1	4	6	-46.1	49.8	7.5	3	Ib	68.4	61.7	90.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2017	NM_012864	Huesken	Mmp7	4316	AGCAUCUCCGCCGAGGCCUgg	AGGCCUCGGCGGAGAUGCU	-2.1	-2.1	-2.4	3	1	6	-47	45.2	-8.7	3	II	68.4	50.3	68.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2018	NM_012864	Huesken	Mmp7	4316	AUCUCCGCCGAGGCCUGGCcc	GCCAGGCCUCGGCGGAGAU	-3.4	-1.1	-4	2	4	6	-48.2	48.9	9.7	3	II	73.7	55.3	36.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2019	NM_012864	Huesken	Mmp7	4316	UCCGCCGAGGCCUGGCCCCgg	GGGGCCAGGCCUCGGCGGA	-3.3	-2.4	-6.3	0	3	6	-52.5	29.8	2.7	2	II	84.2	53.9	50.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2020	NM_012864	Huesken	Mmp7	4316	GCCGAGGCCUGGCCCCGGUgc	ACCGGGGCCAGGCCUCGGC	-2.2	-3.4	-11.2	1	-1	8	-52.3	15.1	1.1	0	III	84.2	23.7	11	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2021	NM_012864	Huesken	Mmp7	4316	CUGGCCCCGGUGCAAAGGCau	GCCUUUGCACCGGGGCCAG	-3.4	-2.1	-4.8	0	1	8	-46.9	31.8	7.8	-1	II	73.7	44.9	32.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2022	NM_012864	Huesken	Mmp7	4316	UGGCCCCGGUGCAAAGGCAug	UGCCUUUGCACCGGGGCCA	-2.1	-2.1	-4.8	2	0	8	-46.9	33.2	-8.7	1	II	68.4	41	59.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2023	NM_012864	Huesken	Mmp7	4316	AAAGGCAUGGCCUAGAGUGuu	CACUCUAGGCCAUGCCUUU	-2.1	-0.9	-2.9	2	4	4	-40.2	56	-4.7	4	Ib	52.6	63.3	100.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2024	NM_012864	Huesken	Mmp7	4316	GCAUGGCCUAGAGUGUUUCcu	GAAACACUCUAGGCCAUGC	-2.4	-3.4	1.5	0	1	4	-39.4	53.3	9.7	4	II	52.6	42.2	53.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2025	NM_012864	Huesken	Mmp7	4316	CAUGGCCUAGAGUGUUUCCug	GGAAACACUCUAGGCCAUG	-3.3	-2.1	0.4	-2	1	4	-39.3	62.2	7.7	3	II	52.6	48.2	89.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2026	NM_012864	Huesken	Mmp7	4316	GGCCUAGAGUGUUUCCUGGcc	CCAGGAAACACUCUAGGCC	-3.3	-3.3	0.1	2	1	4	-41.5	54.4	5.4	2	II	57.9	37.8	33.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2027	NM_012864	Huesken	Mmp7	4316	CCUAGAGUGUUUCCUGGCCca	GGCCAGGAAACACUCUAGG	-3.3	-3.3	0.1	0	1	4	-41.5	50.5	10.8	2	II	57.9	45	54.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2028	NM_012864	Huesken	Mmp7	4316	CUAGAGUGUUUCCUGGCCCau	GGGCCAGGAAACACUCUAG	-3.3	-2.1	0.1	0	3	5	-41.5	52.5	10.5	3	II	57.9	60.4	83.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2029	NM_012864	Huesken	Mmp7	4316	GUUUCCUGGCCCAUCAAAUgg	AUUUGAUGGGCCAGGAAAC	-1.1	-2.2	0.1	2	0	5	-37.8	66.6	-8.9	4	II	47.4	41.5	10.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2030	NM_012864	Huesken	Mmp7	4316	UGGCCCAUCAAAUGGGAAGuu	CUUCCCAUUUGAUGGGCCA	-2.1	-2.1	-4.1	1	1	5	-40.1	64.6	2.3	4	II	52.6	57.3	85	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2031	NM_012864	Huesken	Mmp7	4316	GCCCAUCAAAUGGGAAGUUgu	AACUUCCCAUUUGAUGGGC	-0.9	-3.4	-4.1	0	-2	4	-37.8	36.4	-1.3	1	III	47.4	25.8	0.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2032	NM_012864	Huesken	Mmp7	4316	GUUGUCUCCGUGAUCUCCCcu	GGGAGAUCACGGAGACAAC	-3.3	-2.2	0.8	2	4	3	-41.3	63.5	7.1	3	II	57.9	61.5	94.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2033	NM_012864	Huesken	Mmp7	4316	UGUCUCCGUGAUCUCCCCUug	AGGGGAGAUCACGGAGACA	-2.1	-2.1	-0.7	1	3	4	-43.6	64.4	6.1	4	II	57.9	57.1	101.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2034	NM_012864	Huesken	Mmp7	4316	CUCCGUGAUCUCCCCUUGCga	GCAAGGGGAGAUCACGGAG	-3.4	-2.1	-0.7	0	0	4	-43.3	47.7	5.5	2	II	63.2	51.1	90.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2035	NM_012864	Huesken	Mmp7	4316	UCCGUGAUCUCCCCUUGCGaa	CGCAAGGGGAGAUCACGGA	-2.4	-2.4	-0.7	1	3	4	-43.6	55.4	-2.3	4	II	63.2	60.9	97.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2036	NM_012864	Huesken	Mmp7	4316	CGUGAUCUCCCCUUGCGAAgc	UUCGCAAGGGGAGAUCACG	-0.9	-2.4	-1.9	0	-2	4	-41.2	49.4	-5.4	0	III	57.9	28	26.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2037	NM_012864	Huesken	Mmp7	4316	UGAUCUCCCCUUGCGAAGCca	GCUUCGCAAGGGGAGAUCA	-3.4	-2.1	-5	1	3	4	-42.1	65.5	10.4	3	Ib	57.9	64.4	105.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2038	NM_012864	Huesken	Mmp7	4316	CCUUGCGAAGCCAAUUAUGau	CAUAAUUGGCUUCGCAAGG	-2.1	-3.3	-1	-1	-1	3	-35.8	53.4	-9.3	2	II	47.4	43.4	63.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2039	NM_012864	Huesken	Mmp7	4316	CUUGCGAAGCCAAUUAUGAug	UCAUAAUUGGCUUCGCAAG	-2.4	-2.1	0.4	0	-1	3	-34.9	59.1	-8.4	4	III	42.1	46.2	75.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2040	NM_012864	Huesken	Mmp7	4316	GAAGCCAAUUAUGAUGUCUgc	AGACAUCAUAAUUGGCUUC	-2.1	-2.4	0.6	0	0	3	-33.9	68.6	1.4	4	III	36.8	47.9	99.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2041	NM_012864	Huesken	Mmp7	4316	AAGCCAAUUAUGAUGUCUGca	CAGACAUCAUAAUUGGCUU	-2.1	-0.9	0.6	2	4	3	-33.6	74.7	-0.3	5	Ib	36.8	66.6	102.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2042	NM_012864	Huesken	Mmp7	4316	AGCCAAUUAUGAUGUCUGCag	GCAGACAUCAUAAUUGGCU	-3.4	-2.1	0.6	2	2	3	-36.1	65.6	10.1	5	Ib	42.1	50.9	95.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2043	NM_012864	Huesken	Mmp7	4316	CCCCAACUAACCCUCUUGAag	UCAAGAGGGUUAGUUGGGG	-2.4	-3.3	1.4	0	-3	4	-40.2	49.7	-3	3	III	52.6	29.4	40.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2044	NM_012864	Huesken	Mmp7	4316	AGUGGGAUUUGCAUACUCCac	GGAGUAUGCAAAUCCCACU	-3.3	-2.1	-1.2	1	4	3	-38.3	63.7	4.8	4	II	47.4	63.2	96.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2045	NM_012864	Huesken	Mmp7	4316	CUGGAAUGCCACUUAGGACug	GUCCUAAGUGGCAUUCCAG	-2.2	-2.1	-1.1	1	1	3	-39.3	57.7	10.4	2	II	52.6	48.3	109.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2046	NM_012864	Huesken	Mmp7	4316	GAAUGCCACUUAGGACUGUuu	ACAGUCCUAAGUGGCAUUC	-2.2	-2.4	-1.3	0	0	3	-38.2	43.1	-4	3	III	47.4	34.4	65.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2047	NM_012864	Huesken	Mmp7	4316	UGCCACUUAGGACUGUUUGgc	CAAACAGUCCUAAGUGGCA	-2.1	-2.1	-1.3	2	2	3	-37.7	74.6	7.4	5	II	47.4	60.7	81.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2048	NM_012864	Huesken	Mmp7	4316	UUAGGACUGUUUGGCAUUAgu	UAAUGCCAAACAGUCCUAA	-1.3	-0.9	1.8	0	0	3	-34.6	58.9	-0.7	6	II	36.8	52.8	105	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2049	NM_012864	Huesken	Mmp7	4316	UGGCAUUAGUGAGAAUUCUgc	AGAAUUCUCACUAAUGCCA	-2.1	-2.1	0.8	3	0	3	-34.9	65.6	-1.3	6	II	36.8	59.4	106.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2050	NM_012864	Huesken	Mmp7	4316	GCAUUAGUGAGAAUUCUGCaa	GCAGAAUUCUCACUAAUGC	-3.4	-3.4	0.2	1	2	2	-35	68	7.1	6	II	42.1	51.4	94.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2051	NM_012864	Huesken	Mmp7	4316	CAUUAGUGAGAAUUCUGCAac	UGCAGAAUUCUCACUAAUG	-2.1	-2.1	0.8	0	0	2	-33.7	75.1	1.6	5	II	36.8	49.7	72.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2052	NM_012864	Huesken	Mmp7	4316	UUAGUGAGAAUUCUGCAACau	GUUGCAGAAUUCUCACUAA	-2.2	-0.9	0.8	0	4	2	-33.6	82.9	15.2	8	Ia	36.8	77.6	122.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2053	NM_012864	Huesken	Mmp7	4316	AGUGAGAAUUCUGCAACAUcu	AUGUUGCAGAAUUCUCACU	-1.1	-2.1	0.8	1	1	2	-34.6	57.2	-0.6	5	II	36.8	45.9	80.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2054	NM_012864	Huesken	Mmp7	4316	GUGAGAAUUCUGCAACAUCug	GAUGUUGCAGAAUUCUCAC	-2.4	-2.2	0.8	0	0	2	-34.9	57.4	9.8	3	II	42.1	52.1	119.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2055	NM_012864	Huesken	Mmp7	4316	GAAUUCUGCAACAUCUGGCac	GCCAGAUGUUGCAGAAUUC	-3.4	-2.4	-0.3	2	4	3	-37	77	7.1	6	II	47.4	61.1	100.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2056	NM_012864	Huesken	Mmp7	4316	UUCUGCAACAUCUGGCACUcc	AGUGCCAGAUGUUGCAGAA	-2.1	-0.9	-1.2	0	1	3	-39	69.4	-6.3	6	II	47.4	66.4	115	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2057	NM_012864	Huesken	Mmp7	4316	UCUGCAACAUCUGGCACUCca	GAGUGCCAGAUGUUGCAGA	-2.4	-2.4	-1.2	-1	3	3	-40.5	54.9	8.1	4	Ib	52.6	57.3	104	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2058	NM_012864	Huesken	Mmp7	4316	UGCAACAUCUGGCACUCCAca	UGGAGUGCCAGAUGUUGCA	-2.1	-2.1	-1.4	1	0	3	-41.4	61.8	1.4	5	II	52.6	54.3	91.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2059	NM_012864	Huesken	Mmp7	4316	AACAUCUGGCACUCCACACcu	GUGUGGAGUGCCAGAUGUU	-2.2	-0.9	-1.6	3	3	3	-40.3	71.6	7.4	5	Ia	52.6	61.1	93.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2060	NM_012864	Huesken	Mmp7	4316	UCUGGCACUCCACACCUGGgc	CCAGGUGUGGAGUGCCAGA	-3.3	-2.4	-2.2	0	3	3	-44.8	48.4	0.1	4	II	63.2	62.8	85.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2061	NM_012864	Huesken	Mmp7	4316	CUGGCACUCCACACCUGGGcu	CCCAGGUGUGGAGUGCCAG	-3.3	-2.1	-2.2	0	1	3	-45.7	42.3	-4.6	-1	II	68.4	44.8	60.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2062	NM_012864	Huesken	Mmp7	4316	GCACUCCACACCUGGGCUUcu	AAGCCCAGGUGUGGAGUGC	-0.9	-3.4	-1.4	1	-1	4	-44.6	37.2	-8.7	1	III	63.2	29	47.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2063	NM_012864	Huesken	Mmp7	4316	CACUCCACACCUGGGCUUCug	GAAGCCCAGGUGUGGAGUG	-2.4	-2.1	-1.4	-2	-1	4	-43.6	51.8	6.1	2	II	63.2	41.9	94	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2064	NM_012864	Huesken	Mmp7	4316	CCACACCUGGGCUUCUGCAuu	UGCAGAAGCCCAGGUGUGG	-2.1	-3.3	-0.3	1	-1	4	-44.5	42.3	-3.1	1	III	63.2	32.5	61.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2065	NM_012864	Huesken	Mmp7	4316	ACACCUGGGCUUCUGCAUUau	AAUGCAGAAGCCCAGGUGU	-0.9	-2.2	-0.3	3	1	4	-41.1	54.4	3.8	4	II	52.6	47.2	86.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2066	NM_012864	Huesken	Mmp7	4316	CUUCUGCAUUAUCUCCAUGac	CAUGGAGAUAAUGCAGAAG	-2.1	-2.1	0.9	0	1	2	-35	71.3	8.1	3	II	42.1	50.9	97.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2067	NM_012864	Huesken	Mmp7	4316	UCUGCAUUAUCUCCAUGACac	GUCAUGGAGAUAAUGCAGA	-2.2	-2.4	0.1	1	3	2	-36.6	75.7	10.5	5	Ib	42.1	56.5	115	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2068	NM_012864	Huesken	Mmp7	4316	UGCAUUAUCUCCAUGACACgg	GUGUCAUGGAGAUAAUGCA	-2.2	-2.1	-1.2	1	3	2	-36.4	81.5	2.4	5	Ia	42.1	68	112.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2069	NM_012864	Huesken	Mmp7	4316	GGACAGCUUUCCAGUCUCCgg	GGAGACUGGAAAGCUGUCC	-3.3	-3.3	-1.2	0	1	2	-41.7	39.3	2.8	1	II	57.9	40.4	88.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2070	NM_012864	Huesken	Mmp7	4316	GCUUUCCAGUCUCCGGCAAac	UUGCCGGAGACUGGAAAGC	-0.9	-3.4	-2.4	1	-2	5	-41.7	47.4	-0.7	1	III	57.9	18.8	1.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2071	NM_012864	Huesken	Mmp7	4316	UUCCAGUCUCCGGCAAACCga	GGUUUGCCGGAGACUGGAA	-3.3	-0.9	-2.4	2	3	5	-41.7	55.5	7.8	4	Ib	57.9	70.4	102.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2072	NM_012864	Huesken	Mmp7	4316	UCCGGCAAACCGAAGAACUuc	AGUUCUUCGGUUUGCCGGA	-2.1	-2.4	-4.7	0	0	5	-39.6	48.7	-8.9	3	II	52.6	56.1	53.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2073	NM_012864	Huesken	Mmp7	4316	CCGGCAAACCGAAGAACUUcu	AAGUUCUUCGGUUUGCCGG	-0.9	-3.3	-3.7	-1	-3	5	-38.1	33.2	-8.6	0	III	52.6	32	1.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2074	NM_012864	Huesken	Mmp7	4316	GAACUUCUGCAUUUCCCUCag	GAGGGAAAUGCAGAAGUUC	-2.4	-2.4	1.8	2	3	3	-37	73.4	15.1	3	II	47.4	53.1	97.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2075	NM_012864	Huesken	Mmp7	4316	AACUUCUGCAUUUCCCUCAgu	UGAGGGAAAUGCAGAAGUU	-2.1	-0.9	1.8	3	0	3	-36.7	85.2	-0.7	8	II	42.1	62	103.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2076	NM_012864	Huesken	Mmp7	4316	ACUUCUGCAUUUCCCUCAGuu	CUGAGGGAAAUGCAGAAGU	-2.1	-2.2	-0.2	1	3	3	-37.9	71.2	5.4	5	Ib	47.4	51.6	83.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2077	NM_012864	Huesken	Mmp7	4316	UCUGCAUUUCCCUCAGUUUgu	AAACUGAGGGAAAUGCAGA	-0.9	-2.4	-0.7	1	0	3	-36.7	73.4	-8.7	6	II	42.1	55.8	116.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2078	NM_012864	Huesken	Mmp7	4316	CAUUUCCCUCAGUUUGUCCac	GGACAAACUGAGGGAAAUG	-3.3	-2.1	2.2	-1	2	3	-36.7	83.1	10	5	II	47.4	55.7	83	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2079	NM_012864	Huesken	Mmp7	4316	CCCUCAGUUUGUCCACUGCac	GCAGUGGACAAACUGAGGG	-3.4	-3.3	-3.7	-1	-1	3	-41.2	57.1	10.8	1	II	57.9	39.2	32.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2080	NM_012864	Huesken	Mmp7	4316	UCAGUUUGUCCACUGCACUgg	AGUGCAGUGGACAAACUGA	-2.1	-2.4	-3.7	1	2	2	-38.9	67.3	-1.6	5	II	47.4	65.1	110.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2081	NM_012864	Huesken	Mmp7	4316	CAGUUUGUCCACUGCACUGgu	CAGUGCAGUGGACAAACUG	-2.1	-2.1	-2.6	-1	0	2	-38.6	65.1	-2.1	3	II	52.6	52.5	100	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2082	NM_012864	Huesken	Mmp7	4316	CCACUGCACUGGUGGCCUUcu	AAGGCCACCAGUGCAGUGG	-0.9	-3.3	-2.9	0	-2	4	-44.3	32.7	-6	0	III	63.2	27.5	22.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2083	NM_012864	Huesken	Mmp7	4316	GCACUGGUGGCCUUCUUUGuu	CAAAGAAGGCCACCAGUGC	-2.1	-3.4	0.5	2	1	4	-40.9	51.6	-2.4	3	II	57.9	44	38.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2084	NM_012864	Huesken	Mmp7	4316	ACUGGUGGCCUUCUUUGUUuu	AACAAAGAAGGCCACCAGU	-0.9	-2.2	0.5	2	2	4	-38.5	60.9	3.8	4	II	47.4	47.1	87.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2085	NM_012864	Huesken	Mmp7	4316	UGGUGGCCUUCUUUGUUUUag	AAAACAAAGAAGGCCACCA	-0.9	-2.1	0.5	0	0	4	-36	76.1	-1	5	II	42.1	51.2	45.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2086	NM_012864	Huesken	Mmp7	4316	UGGCCUUCUUUGUUUUAGAgu	UCUAAAACAAAGAAGGCCA	-2.4	-2.1	0.6	2	0	4	-34.2	81.4	-1.4	4	II	36.8	56.2	95.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2087	NM_012864	Huesken	Mmp7	4316	CUUCUUUGUUUUAGAGUCGug	CGACUCUAAAACAAAGAAG	-2.4	-2.1	0.5	0	1	2	-31.2	73.8	-1.6	5	II	36.8	59.2	113.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2088	NM_012864	Huesken	Mmp7	4316	CUUUGUUUUAGAGUCGUGAag	UCACGACUCUAAAACAAAG	-2.4	-2.1	3.2	0	-1	2	-32.5	79.5	-3.4	6	II	36.8	52.2	108	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2089	NM_012864	Huesken	Mmp7	4316	UGUUUUAGAGUCGUGAAGGua	CCUUCACGACUCUAAAACA	-3.3	-2.1	4.8	0	4	2	-34.9	78.4	0	7	Ia	42.1	71.2	126.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2090	NM_012864	Huesken	Mmp7	4316	UUUUAGAGUCGUGAAGGUAaa	UACCUUCACGACUCUAAAA	-1.3	-0.9	4.8	0	1	2	-34.1	68.2	2	8	II	36.8	58.1	110	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2091	NM_012864	Huesken	Mmp7	4316	UUUAGAGUCGUGAAGGUAAaa	UUACCUUCACGACUCUAAA	-0.9	-0.9	4	1	0	2	-34.1	68.3	-6.3	8	II	36.8	59.6	130.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2092	NM_012864	Huesken	Mmp7	4316	UUAGAGUCGUGAAGGUAAAau	UUUACCUUCACGACUCUAA	-0.9	-0.9	3.8	1	0	2	-34.1	59.7	-3.6	7	II	36.8	54.1	110	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2093	NM_012864	Huesken	Mmp7	4316	GAGUCGUGAAGGUAAAAUUuc	AAUUUUACCUUCACGACUC	-0.9	-2.4	3.8	1	-2	2	-32.7	71.9	-4	4	III	36.8	45.4	76.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2094	NM_012864	Huesken	Mmp7	4316	AGUCGUGAAGGUAAAAUUUcc	AAAUUUUACCUUCACGACU	-0.9	-2.1	3.8	2	0	2	-31.2	68.4	-3.5	5	II	31.6	52.2	74.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2095	NM_012864	Huesken	Mmp7	4316	UCGUGAAGGUAAAAUUUCCua	GGAAAUUUUACCUUCACGA	-3.3	-2.4	0	1	2	2	-32.6	69.8	7.1	6	Ib	36.8	67.3	126.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2096	NM_012864	Huesken	Mmp7	4316	GUGAAGGUAAAAUUUCCUAag	UAGGAAAUUUUACCUUCAC	-1.3	-2.2	-0.7	0	-1	2	-31.2	73.1	3.6	5	III	31.6	46.2	86.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2097	NM_012864	Huesken	Mmp7	4316	AGGUAAAAUUUCCUAAGAUaa	AUCUUAGGAAAUUUUACCU	-1.1	-2.1	-0.6	1	1	2	-30.1	70.4	1.1	5	II	26.3	47	79.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2098	NM_012864	Huesken	Mmp7	4316	GGUAAAAUUUCCUAAGAUAau	UAUCUUAGGAAAUUUUACC	-1.3	-3.3	0.8	0	-3	2	-29.3	67.8	-5.8	4	II	26.3	35.7	28.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2099	NM_012864	Huesken	Mmp7	4316	AAAUUUCCUAAGAUAAUUCug	GAAUUAUCUUAGGAAAUUU	-2.4	-0.9	0.8	1	4	2	-26.9	99.6	9.4	8	Ia	21.1	74.5	116.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2100	NM_012864	Huesken	Mmp7	4316	UUUCCUAAGAUAAUUCUGCgc	GCAGAAUUAUCUUAGGAAA	-3.4	-0.9	0.8	2	5	2	-31.6	89.9	7.1	8	Ia	31.6	83.7	131.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2101	NM_012864	Huesken	Mmp7	4316	CCUAAGAUAAUUCUGCGCCug	GGCGCAGAAUUAUCUUAGG	-3.3	-3.3	0.9	-1	2	5	-36.5	69.1	15.9	5	II	47.4	58.3	134.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2102	NM_012864	Huesken	Mmp7	4316	CUAAGAUAAUUCUGCGCCUgu	AGGCGCAGAAUUAUCUUAG	-2.1	-2.1	0.9	-1	0	5	-35.3	57.9	-8.3	4	II	42.1	50.1	66	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2103	NM_012864	Huesken	Mmp7	4316	AAGAUAAUUCUGCGCCUGUuc	ACAGGCGCAGAAUUAUCUU	-2.2	-0.9	0.9	0	1	5	-36.2	64.2	-1.6	7	II	42.1	56	75.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2104	NM_012864	Huesken	Mmp7	4316	AUAAUUCUGCGCCUGUUCCca	GGAACAGGCGCAGAAUUAU	-3.3	-1.1	3.6	2	5	5	-37.4	81.9	9.8	7	Ia	47.4	69.6	104.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2105	NM_012864	Huesken	Mmp7	4316	UAAUUCUGCGCCUGUUCCCac	GGGAACAGGCGCAGAAUUA	-3.3	-1.3	3.6	1	5	5	-39.6	76	2.7	8	Ia	52.6	74.9	93.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2106	NM_012864	Huesken	Mmp7	4316	AAUUCUGCGCCUGUUCCCAcu	UGGGAACAGGCGCAGAAUU	-2.1	-0.9	-0.7	2	3	5	-40.4	66	-0.8	6	II	52.6	52.9	46.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2107	NM_012864	Huesken	Mmp7	4316	CUGUUCCCACUGAAGUGCGgu	CGCACUUCAGUGGGAACAG	-2.4	-2.1	-1.9	-1	1	3	-40.3	53.3	-4.6	1	II	57.9	50.5	91.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2108	NM_012864	Huesken	Mmp7	4316	UGUUCCCACUGAAGUGCGGuc	CCGCACUUCAGUGGGAACA	-3.3	-2.1	-4.6	0	4	4	-41.5	56.1	-2.6	3	II	57.9	52.9	91.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2109	NM_012864	Huesken	Mmp7	4316	CACUGAAGUGCGGUCACUUcu	AAGUGACCGCACUUCAGUG	-0.9	-2.1	-2.6	-1	-1	4	-39.2	47.5	-6	2	II	52.6	40.9	79.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2110	NM_012864	Huesken	Mmp7	4316	ACUGAAGUGCGGUCACUUCuc	GAAGUGACCGCACUUCAGU	-2.4	-2.2	-7.1	2	2	4	-39.5	54.7	10.1	5	Ib	52.6	51.5	40.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2111	NM_012864	Huesken	Mmp7	4316	CUGAAGUGCGGUCACUUCUcc	AGAAGUGACCGCACUUCAG	-2.1	-2.1	-7.3	1	-2	4	-39.4	61.7	2.2	4	II	52.6	52.5	32.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2112	NM_012864	Huesken	Mmp7	4316	AGUGCGGUCACUUCUCCGGcu	CCGGAGAAGUGACCGCACU	-3.3	-2.1	-1.9	2	4	4	-43.3	58.9	0.7	3	II	63.2	57.9	94.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2113	NM_012864	Huesken	Mmp7	4316	GGUCACUUCUCCGGCUUCCug	GGAAGCCGGAGAAGUGACC	-3.3	-3.3	0.7	2	1	5	-43.2	47	5.4	3	II	63.2	41.9	83	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2114	NM_012864	Huesken	Mmp7	4316	CACUUCUCCGGCUUCCUGGga	CCAGGAAGCCGGAGAAGUG	-3.3	-2.1	-0.3	1	1	5	-42.8	69.7	-2	4	II	63.2	54.4	72.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2115	NM_012864	Huesken	Mmp7	4316	ACUUCUCCGGCUUCCUGGGac	CCCAGGAAGCCGGAGAAGU	-3.3	-2.2	-0.6	2	4	5	-44	61.1	0.7	3	Ib	63.2	50.7	64.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2116	NM_012864	Huesken	Mmp7	4316	GGCUUCCUGGGACAGUGGCag	GCCACUGUCCCAGGAAGCC	-3.4	-3.3	-0.3	1	1	3	-46	44	9.8	1	II	68.4	34.4	66	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2117	NM_012864	Huesken	Mmp7	4316	UUCCUGGGACAGUGGCAGGgc	CCUGCCACUGUCCCAGGAA	-3.3	-0.9	-2.9	0	3	3	-44.7	50.8	2.3	4	II	63.2	60	67.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2118	NM_012864	Huesken	Mmp7	4316	UGGGACAGUGGCAGGGCCAgg	UGGCCCUGCCACUGUCCCA	-2.1	-2.1	-3.1	-1	0	5	-48.1	32.3	-6	3	II	68.4	48.6	93.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2119	NM_012864	Huesken	Mmp7	4316	AGUGGCAGGGCCAGGCAGCcu	GCUGCCUGGCCCUGCCACU	-3.4	-2.1	-3.2	1	3	5	-49.1	28	0.1	2	II	73.7	49.7	64.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2120	NM_025237	Huesken	SOST	50964	GGCCGAGCGGCCUCGGUCCcg	GGACCGAGGCCGCUCGGCC	-3.3	-3.3	-6.9	2	0	6	-50.8	24	2.7	0	II	84.2	35.4	50.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2121	NM_025237	Huesken	SOST	50964	GGCCUCGGUCCCGAAGUCCuu	GGACUUCGGGACCGAGGCC	-3.3	-3.3	-5.7	1	0	4	-47.1	29.4	2.7	1	II	73.7	37.7	53.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2122	NM_025237	Huesken	SOST	50964	CCUCGGUCCCGAAGUCCUUga	AAGGACUUCGGGACCGAGG	-0.9	-3.3	-5.3	1	-2	4	-43.4	31.3	-8.6	0	III	63.2	32.2	58.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2123	NM_025237	Huesken	SOST	50964	UCGGUCCCGAAGUCCUUGAgc	UCAAGGACUUCGGGACCGA	-2.4	-2.4	-1.8	1	-1	4	-42.5	59.2	-1.5	4	II	57.9	49.8	61.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2124	NM_025237	Huesken	SOST	50964	CGGUCCCGAAGUCCUUGAGcu	CUCAAGGACUUCGGGACCG	-2.1	-2.4	0.1	-1	-1	4	-42.2	54.8	3.4	1	II	63.2	31.5	62.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2125	NM_025237	Huesken	SOST	50964	GUCCCGAAGUCCUUGAGCUcc	AGCUCAAGGACUUCGGGAC	-2.1	-2.2	0	2	1	4	-42	50.7	-6.3	1	III	57.9	41.1	64.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2126	NM_025237	Huesken	SOST	50964	CCCGAAGUCCUUGAGCUCCga	GGAGCUCAAGGACUUCGGG	-3.3	-3.3	-2.1	0	-1	4	-43.1	39.4	11.1	1	II	63.2	45.6	75	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2127	NM_025237	Huesken	SOST	50964	CGAAGUCCUUGAGCUCCGAcu	UCGGAGCUCAAGGACUUCG	-2.4	-2.4	-2.9	-1	-2	3	-41.3	38	-5.8	0	III	57.9	31.1	61.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2128	NM_025237	Huesken	SOST	50964	GAGCUCCGACUGGUUGUGGaa	CCACAACCAGUCGGAGCUC	-3.3	-2.4	-0.8	1	2	3	-43	45.1	2.3	2	II	63.2	39.8	80.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2129	NM_025237	Huesken	SOST	50964	AGCGGGUGAGGCGCUUGCAcu	UGCAAGCGCCUCACCCGCU	-2.1	-2.1	-2.5	2	0	5	-46.4	32.4	-6.1	1	II	68.4	38.3	66.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2130	NM_025237	Huesken	SOST	50964	GGUGAGGCGCUUGCACUUGca	CAAGUGCAAGCGCCUCACC	-2.1	-3.3	-1.7	1	0	5	-42.5	34.7	5.7	2	II	63.2	38	68.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2131	NM_025237	Huesken	SOST	50964	ACUUGCACGAGGCCACCAGgc	CUGGUGGCCUCGUGCAAGU	-2.1	-2.2	-0.3	2	3	4	-43.7	50	2.4	5	Ib	63.2	48.9	52.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2132	NM_025237	Huesken	SOST	50964	GAGGCCACCAGGCGCACCUug	AGGUGCGCCUGGUGGCCUC	-2.1	-2.4	-4.2	0	0	5	-48.5	37.2	-1.6	1	III	73.7	40.7	71.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2133	NM_025237	Huesken	SOST	50964	CCAGGCGCACCUUGCGCGCgc	GCGCGCAAGGUGCGCCUGG	-3.4	-3.3	-8.2	-2	1	6	-47.7	26	6.1	0	II	78.9	38.4	41.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2134	NM_025237	Huesken	SOST	50964	CGCACCUUGCGCGCGCGCGgc	CGCGCGCGCGCAAGGUGCG	-2.4	-2.4	-5.9	1	0	11	-47.5	34.2	-4.4	0	II	84.2	39.2	60.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2135	NM_025237	Huesken	SOST	50964	CACCUUGCGCGCGCGCGGCgc	GCCGCGCGCGCGCAAGGUG	-3.4	-2.1	-4.6	1	1	13	-48.4	28.6	3.1	1	II	84.2	42.5	57.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2136	NM_025237	Huesken	SOST	50964	GCGCGCGCGGCGCCUCACCac	GGUGAGGCGCCGCGCGCGC	-3.3	-3.4	-5.2	2	0	14	-51.1	15.5	7.5	-1	II	89.5	34.3	26	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2137	NM_025237	Huesken	SOST	50964	GCGCGCGGCGCCUCACCACcg	GUGGUGAGGCGCCGCGCGC	-2.2	-3.4	-7.1	2	0	12	-49.6	17.7	2.7	-1	II	84.2	30	65.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2138	NM_025237	Huesken	SOST	50964	CGCGGCGCCUCACCACCGGga	CCGGUGGUGAGGCGCCGCG	-3.3	-2.4	-7.1	0	0	9	-49.4	17.4	-2	-1	II	84.2	33.8	35.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2139	NM_025237	Huesken	SOST	50964	CGCCUCACCACCGGGACACag	GUGUCCCGGUGGUGAGGCG	-2.2	-2.4	-0.6	0	-1	5	-46.7	32.5	0.7	2	II	73.7	36.9	62.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2140	NM_025237	Huesken	SOST	50964	CCACCGGGACACAGCAGCUgc	AGCUGCUGUGUCCCGGUGG	-2.1	-3.3	-3.4	-1	-1	5	-46.1	24.7	-8.6	0	III	68.4	34.5	66	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2141	NM_025237	Huesken	SOST	50964	CACGCGCUGCGCGCGGUAGcg	CUACCGCGCGCAGCGCGUG	-2.1	-2.1	-6.8	0	-1	8	-46.4	30.4	-4.4	0	II	78.9	32.3	50.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2142	NM_025237	Huesken	SOST	50964	ACGCGCUGCGCGCGGUAGCgg	GCUACCGCGCGCAGCGCGU	-3.4	-2.2	-6.8	3	2	8	-47.7	28.8	7.5	1	II	78.9	44.8	51.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2143	NM_025237	Huesken	SOST	50964	GUCGGGCCCACUAGGUCGCca	GCGACCUAGUGGGCCCGAC	-3.4	-2.2	-1.5	0	2	7	-47.1	32.5	5.5	0	II	73.7	41.4	66	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2144	NM_025237	Huesken	SOST	50964	CCACUAGGUCGCCACCACUug	AGUGGUGGCGACCUAGUGG	-2.1	-3.3	-1.8	0	-2	4	-44.1	34.2	-5.9	1	III	63.2	38.6	78.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2145	NM_025237	Huesken	SOST	50964	ACUAGGUCGCCACCACUUGcc	CAAGUGGUGGCGACCUAGU	-2.1	-2.2	-1.8	3	2	4	-41.7	49.5	0.1	4	Ib	57.9	53.3	64.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2146	NM_025237	Huesken	SOST	50964	CACCACUUGCCGCGGCCGAug	UCGGCCGCGGCAAGUGGUG	-2.4	-2.1	-6.9	1	-2	10	-46.7	28.5	-3	1	III	73.7	29.1	66	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2147	NM_025237	Huesken	SOST	50964	GCGGCCGAUGGCGUUGGGCag	GCCCAACGCCAUCGGCCGC	-3.4	-3.4	-2.1	0	2	7	-48.1	27.6	7.4	-1	II	78.9	34.5	64.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2148	NM_025237	Huesken	SOST	50964	UGGCGUUGGGCAGCAGGCGcg	CGCCUGCUGCCCAACGCCA	-2.4	-2.1	0	3	3	4	-47.3	32.8	-2.4	3	II	73.7	58.5	64.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2149	NM_025237	Huesken	SOST	50964	UUGGGCAGCAGGCGCGCCGgg	CGGCGCGCCUGCUGCCCAA	-2.4	-0.9	-3.5	0	4	9	-48.8	38.5	2.4	4	II	78.9	65.8	84.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2150	NM_025237	Huesken	SOST	50964	GCAGGCGCGCCGGGCCGCAcu	UGCGGCCCGGCGCGCCUGC	-2.1	-3.4	-3.5	0	-1	15	-52.8	-2.8	-6.1	0	III	89.5	19.6	52.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2151	NM_025237	Huesken	SOST	50964	GGGCCGCACUGGCCGGAGCac	GCUCCGGCCAGUGCGGCCC	-3.4	-3.3	-7	2	0	7	-51.2	23.8	9.8	-2	II	84.2	28.9	53	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2152	NM_025237	Huesken	SOST	50964	CACACCAGCUCGGUGACCGgc	CGGUCACCGAGCUGGUGUG	-2.4	-2.1	-3.8	0	2	3	-44.3	48.2	-2	1	II	68.4	49.6	52.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2153	NM_025237	Huesken	SOST	50964	CUCGGUGACCGGCUUGGCGcu	CGCCAAGCCGGUCACCGAG	-2.4	-2.1	-1.6	0	2	5	-45.7	41	2.7	0	II	73.7	47.1	59.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2154	NM_025237	Huesken	SOST	50964	GGUGACCGGCUUGGCGCUGcg	CAGCGCCAAGCCGGUCACC	-2.1	-3.3	-1.6	0	1	5	-46.4	21.8	5.7	0	II	73.7	28.5	50.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2155	NM_025237	Huesken	SOST	50964	GACCGGCUUGGCGCUGCGGca	CCGCAGCGCCAAGCCGGUC	-3.3	-2.4	-1.6	1	2	5	-47.9	25.5	-2.4	-1	II	78.9	35.5	51.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2156	NM_025237	Huesken	SOST	50964	CGGCUUGGCGCUGCGGCACgg	GUGCCGCAGCGCCAAGCCG	-2.2	-2.4	-3.5	1	-1	5	-47.7	29.9	6.1	0	II	78.9	36.7	49.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2157	NM_025237	Huesken	SOST	50964	GCUUGGCGCUGCGGCACGGcc	CCGUGCCGCAGCGCCAAGC	-3.3	-3.4	-3.8	0	2	5	-47.7	20.3	-2.4	0	II	78.9	28.9	50.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2158	NM_025237	Huesken	SOST	50964	GCUGCGGCACGGCCCAUCGgu	CGAUGGGCCGUGCCGCAGC	-2.4	-3.4	-2.7	0	1	6	-48.1	33.7	2.4	1	II	78.9	39.3	51	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2159	NM_025237	Huesken	SOST	50964	CUGCGGCACGGCCCAUCGGuc	CCGAUGGGCCGUGCCGCAG	-3.3	-2.1	-2.7	1	1	6	-48	25.8	-2	-1	II	78.9	41	54.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2160	NM_025237	Huesken	SOST	50964	CCCAUCGGUCACGUAGCGGgu	CCGCUACGUGACCGAUGGG	-3.3	-3.3	0.2	-1	1	4	-43.9	39.4	0.3	2	II	68.4	39.9	64.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2161	NM_025237	Huesken	SOST	50964	CCAUCGGUCACGUAGCGGGug	CCCGCUACGUGACCGAUGG	-3.3	-3.3	0.3	0	1	5	-43.9	44.6	-4.4	3	II	68.4	47	77.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2162	NM_025237	Huesken	SOST	50964	CGGUCACGUAGCGGGUGAAgu	UUCACCCGCUACGUGACCG	-0.9	-2.4	-1.9	-2	-4	5	-42.6	31.5	-8.1	0	III	63.2	15.8	57.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2163	NM_025237	Huesken	SOST	50964	GGUCACGUAGCGGGUGAAGug	CUUCACCCGCUACGUGACC	-2.1	-3.3	-1.9	0	0	5	-42.3	32.6	0.4	1	II	63.2	27.3	59.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2164	NM_025237	Huesken	SOST	50964	GUAGCGGGUGAAGUGCAGCuc	GCUGCACUUCACCCGCUAC	-3.4	-2.2	0.3	0	3	5	-43	40.9	12	2	II	63.2	50.6	75.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2165	NM_025237	Huesken	SOST	50964	GGGUGAAGUGCAGCUCGCGgc	CGCGAGCUGCACUUCACCC	-2.4	-3.3	-0.9	0	1	4	-44.3	28.9	-2.4	1	II	68.4	38.5	54.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2166	NM_025237	Huesken	SOST	50964	GGUGAAGUGCAGCUCGCGGca	CCGCGAGCUGCACUUCACC	-3.3	-3.3	-0.9	1	3	5	-44.3	38.6	9.7	2	II	68.4	38.7	66.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2167	NM_025237	Huesken	SOST	50964	GCAGCUGUACUCGGACACGuc	CGUGUCCGAGUACAGCUGC	-2.4	-3.4	-0.2	-1	1	3	-42.4	32.8	-2.4	1	II	63.2	40.7	54.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2168	NM_025237	Huesken	SOST	50964	CAGCUGUACUCGGACACGUcu	ACGUGUCCGAGUACAGCUG	-2.2	-2.1	-0.2	2	-1	3	-41.2	42.3	-8.3	2	III	57.9	45	74.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2169	NM_025237	Huesken	SOST	50964	AGCUGUACUCGGACACGUCuu	GACGUGUCCGAGUACAGCU	-2.4	-2.1	-0.2	1	2	3	-41.5	52.3	4.8	3	Ib	57.9	52.6	75.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2170	NM_025237	Huesken	SOST	50964	CUGUACUCGGACACGUCUUug	AAGACGUGUCCGAGUACAG	-0.9	-2.1	-0.2	1	-2	3	-39	58.1	-5.9	4	II	52.6	45.9	87.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2171	NM_025237	Huesken	SOST	50964	CUUUGGUCUCAAAGGGGUGgu	CACCCCUUUGAGACCAAAG	-2.1	-2.1	-2.2	-1	1	4	-38.6	52.6	-2.3	3	II	52.6	49.1	72.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2172	NM_025237	Huesken	SOST	50964	GGUGGUGGGGAGGCCGCCCuc	GGGCGGCCUCCCCACCACC	-3.3	-3.3	-3.1	1	2	8	-52	21.2	9.7	0	II	84.2	40.8	64.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2173	NM_025237	Huesken	SOST	50964	GGGAGGCCGCCCUCCGUUCuc	GAACGGAGGGCGGCCUCCC	-2.4	-3.3	-8	1	-1	8	-49.2	29.7	2.7	0	II	78.9	34.2	52.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2174	NM_025237	Huesken	SOST	50964	UCUCCGCCCGGUUCAUGGUcu	ACCAUGAACCGGGCGGAGA	-2.2	-2.4	-1.3	2	2	8	-44.6	54.7	-1	2	II	63.2	47.7	69.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2175	NM_025237	Huesken	SOST	50964	UCCGCCCGGUUCAUGGUCUug	AGACCAUGAACCGGGCGGA	-2.1	-2.4	-1.3	1	1	8	-44.6	48.2	-6.6	2	II	63.2	49.2	78.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2176	NM_025237	Huesken	SOST	50964	CCCGGUUCAUGGUCUUGUUgu	AACAAGACCAUGAACCGGG	-0.9	-3.3	-0.7	0	-3	5	-39.2	54.6	-6	1	III	52.6	31.9	69.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2177	NM_025237	Huesken	SOST	50964	CGGUUCAUGGUCUUGUUGUuc	ACAACAAGACCAUGAACCG	-2.2	-2.4	1.4	0	-2	3	-36.9	70	-6	4	III	47.4	44.1	52.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2178	NM_025237	Huesken	SOST	50964	GUUGUUCUCCAGCUCCGGUgg	ACCGGAGCUGGAGAACAAC	-2.2	-2.2	-1.8	1	2	4	-41.8	59.5	3.1	1	II	57.9	42.3	83.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2179	NM_025237	Huesken	SOST	50964	UGUUCUCCAGCUCCGGUGGag	CCACCGGAGCUGGAGAACA	-3.3	-2.1	-1.8	0	3	4	-44.1	68.2	3.1	4	Ib	63.2	58.3	86.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2180	NM_025237	Huesken	SOST	50964	UCUCCAGCUCCGGUGGAGGcu	CCUCCACCGGAGCUGGAGA	-3.3	-2.4	-5.6	1	4	4	-46.7	44.3	0	3	II	68.4	54.2	68.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2181	NM_025237	Huesken	SOST	50964	GCUCGGGGUACUCUCCGAGcu	CUCGGAGAGUACCCCGAGC	-2.1	-3.4	-6.5	1	2	5	-45.1	37	5.4	1	II	68.4	35.6	44.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2182	NM_025237	Huesken	SOST	50964	CUCUCCGAGCUCGGGGAUGau	CAUCCCCGAGCUCGGAGAG	-2.1	-2.1	-3.6	-1	-1	5	-45	35	-4.4	1	II	68.4	38.2	50.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2183	NM_025237	Huesken	SOST	50964	CCGAGCUCGGGGAUGAUUUcc	AAAUCAUCCCCGAGCUCGG	-0.9	-3.3	-2.5	1	-3	5	-41.3	50.1	-6.2	1	III	57.9	38.5	49.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2184	NM_025237	Huesken	SOST	50964	UCCGUGGCAUCAUUCUUGAac	UCAAGAAUGAUGCCACGGA	-2.4	-2.4	0.7	0	0	3	-38.7	62.4	-3.8	6	II	47.4	50.5	68.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2185	NM_025237	Huesken	SOST	50964	UGGCAUCAUUCUUGAACGCcu	GCGUUCAAGAAUGAUGCCA	-3.4	-2.1	-2.4	0	3	3	-37.3	61	10.8	3	II	47.4	58.2	93.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2186	NM_025237	Huesken	SOST	50964	CAUCAUUCUUGAACGCCUGcc	CAGGCGUUCAAGAAUGAUG	-2.1	-2.1	-0.6	1	1	4	-36	61.8	-1.9	4	II	47.4	54.3	82.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2187	NM_025237	Huesken	SOST	50964	CUUGAACGCCUGCCACCCCug	GGGGUGGCAGGCGUUCAAG	-3.3	-2.1	0	0	2	4	-44.8	36.3	10.5	2	II	68.4	48.9	48.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2188	NM_025237	Huesken	SOST	50964	AACGCCUGCCACCCCUGGCcc	GCCAGGGGUGGCAGGCGUU	-3.4	-0.9	-5.1	3	4	4	-48.2	51.1	9.8	2	II	73.7	56.4	77.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2189	NM_025237	Huesken	SOST	50964	CCUGCCACCCCUGGCCCUCca	GAGGGCCAGGGGUGGCAGG	-2.4	-3.3	-5.1	-1	0	5	-50.4	28.9	6.1	0	II	78.9	37.6	71.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2190	NM_025237	Huesken	SOST	50964	GCCACCCCUGGCCCUCCACua	GUGGAGGGCCAGGGGUGGC	-2.2	-3.4	-3.4	0	0	5	-50.5	34.8	7.5	-1	II	78.9	28.1	52.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2191	NM_025237	Huesken	SOST	50964	CACCCCUGGCCCUCCACUAca	UAGUGGAGGGCCAGGGGUG	-1.3	-2.1	-1.6	2	-3	5	-47.2	41.7	-10.5	0	III	68.4	34.1	72	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2192	NM_025237	Huesken	SOST	50964	ACCCCUGGCCCUCCACUACac	GUAGUGGAGGGCCAGGGGU	-2.2	-2.2	-1.6	3	1	5	-47.3	46.2	10.5	2	II	68.4	44.2	63.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2193	NM_025237	Huesken	SOST	50964	CCUGGCCCUCCACUACACGga	CGUGUAGUGGAGGGCCAGG	-2.4	-3.3	-1.6	-1	1	5	-45.2	35.7	0.4	-1	II	68.4	40.1	60.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2194	NM_025237	Huesken	SOST	50964	CUGGCCCUCCACUACACGGaa	CCGUGUAGUGGAGGGCCAG	-3.3	-2.1	-1.6	0	1	5	-45.2	49	-2.1	-1	II	68.4	49.5	55.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2195	NM_005450	Huesken	NOG	9241	CUGACAGCGCCACCGCAGCac	GCUGCGGUGGCGCUGUCAG	-3.4	-2.1	-2.8	0	0	5	-46.5	35.8	5.5	1	II	73.7	46.1	80.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2196	NM_005450	Huesken	NOG	9241	CCACCGCAGCACCGUGAGGug	CCUCACGGUGCUGCGGUGG	-3.3	-3.3	-0.9	0	0	4	-46.4	24.8	0.4	0	II	73.7	31.7	70.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2197	NM_005450	Huesken	NOG	9241	ACCGCAGCACCGUGAGGUGca	CACCUCACGGUGCUGCGGU	-2.1	-2.2	-3.8	0	2	4	-45.3	30.9	-2.4	1	II	68.4	37.3	56.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2198	NM_005450	Huesken	NOG	9241	GAGGUGCACGGACUUGGACgg	GUCCAAGUCCGUGCACCUC	-2.2	-2.4	1.2	1	2	3	-43.1	44.1	12.1	1	II	63.2	39	55.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2199	NM_005450	Huesken	NOG	9241	GUGCACGGACUUGGACGGCuu	GCCGUCCAAGUCCGUGCAC	-3.4	-2.2	0.9	0	2	4	-44.4	27.1	13.1	2	II	68.4	38.5	66.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2200	NM_005450	Huesken	NOG	9241	GGACUUGGACGGCUUGCACac	GUGCAAGCCGUCCAAGUCC	-2.2	-3.3	1.5	1	2	4	-42.8	47.2	12.1	2	II	63.2	37.2	75.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2201	NM_005450	Huesken	NOG	9241	UGGACGGCUUGCACACCAUgc	AUGGUGUGCAAGCCGUCCA	-1.1	-2.1	-3.6	0	0	4	-42.7	48.2	-8.9	3	II	57.9	48.5	86.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2202	NM_005450	Huesken	NOG	9241	ACGGCUUGCACACCAUGCCcu	GGCAUGGUGUGCAAGCCGU	-3.3	-2.2	-3.8	3	3	4	-43.7	52.4	7.5	2	II	63.2	59.7	79.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2203	NM_005450	Huesken	NOG	9241	GGCUUGCACACCAUGCCCUcg	AGGGCAUGGUGUGCAAGCC	-2.1	-3.3	-2.4	1	0	4	-44.5	46.2	-8.9	1	III	63.2	37.7	75.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2204	NM_005450	Huesken	NOG	9241	CGGAGCACGAGCGCUUACUga	AGUAAGCGCUCGUGCUCCG	-2.1	-2.4	-2.7	0	-3	4	-42.6	43.5	-8.3	1	III	63.2	39.6	51	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2205	NM_005450	Huesken	NOG	9241	CACGAGCGCUUACUGAAGCag	GCUUCAGUAAGCGCUCGUG	-3.4	-2.1	-2.5	0	1	4	-39.9	45.8	12.8	0	II	57.9	47.4	84.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2206	NM_005450	Huesken	NOG	9241	GCGCUUACUGAAGCAGCUGcc	CAGCUGCUUCAGUAAGCGC	-2.1	-3.4	-2.5	1	0	4	-40.5	41.4	2.3	0	II	57.9	41.7	56.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2207	NM_005450	Huesken	NOG	9241	CGCUUACUGAAGCAGCUGCcc	GCAGCUGCUUCAGUAAGCG	-3.4	-2.4	-2.5	0	-1	3	-40.5	57.1	10.1	2	II	57.9	43.3	63.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2208	NM_005450	Huesken	NOG	9241	CGCGGCCAAAAGCGGCUGCcc	GCAGCCGCUUUUGGCCGCG	-3.4	-2.4	-3.7	-2	-1	7	-45.2	31.9	10.1	0	II	73.7	34	46.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2209	NM_005450	Huesken	NOG	9241	AAAAGCGGCUGCCCAGGUCgu	GACCUGGGCAGCCGCUUUU	-2.4	-0.9	-1.7	2	4	5	-43.6	47.9	7.5	4	Ib	63.2	55.7	77.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2210	NM_005450	Huesken	NOG	9241	AAGCGGCUGCCCAGGUCGUuc	ACGACCUGGGCAGCCGCUU	-2.2	-0.9	-1.6	2	2	5	-46.4	28.2	-11.3	1	II	68.4	41.1	51.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2211	NM_005450	Huesken	NOG	9241	GCGGCUGCCCAGGUCGUUCca	GAACGACCUGGGCAGCCGC	-2.4	-3.4	-0.8	1	0	5	-46.7	38.7	12	1	II	73.7	38.8	59.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2212	NM_005450	Huesken	NOG	9241	CGGCUGCCCAGGUCGUUCCac	GGAACGACCUGGGCAGCCG	-3.3	-2.4	-0.8	1	-1	4	-46.6	46.6	5.4	2	II	73.7	45	51.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2213	NM_005450	Huesken	NOG	9241	CCAGGUCGUUCCACGCGUAca	UACGCGUGGAACGACCUGG	-1.3	-3.3	0	-1	-3	4	-42.6	26.5	-13	0	III	63.2	27.1	51.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2214	NM_005450	Huesken	NOG	9241	UCGUUCCACGCGUACAGCAcg	UGCUGUACGCGUGGAACGA	-2.1	-2.4	-0.9	1	0	4	-41.5	55	-6.1	4	II	57.9	51.8	85.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2215	NM_005450	Huesken	NOG	9241	UCCACGCGUACAGCACGGGgc	CCCGUGCUGUACGCGUGGA	-3.3	-2.4	-5.4	0	3	4	-44.8	38.3	-2.4	3	II	68.4	53.7	60.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2216	NM_005450	Huesken	NOG	9241	GCGUACAGCACGGGGCAGAau	UCUGCCCCGUGCUGUACGC	-2.4	-3.4	-0.1	0	-3	6	-45.7	26	-3.4	3	III	68.4	24.9	61	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2217	NM_005450	Huesken	NOG	9241	GUACAGCACGGGGCAGAAUgu	AUUCUGCCCCGUGCUGUAC	-1.1	-2.2	0.2	2	-1	6	-41.9	33.2	-1.3	2	III	57.9	30.7	51	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2218	NM_005450	Huesken	NOG	9241	ACAGCACGGGGCAGAAUGUcu	ACAUUCUGCCCCGUGCUGU	-2.2	-2.2	0.2	1	1	6	-42.7	33.9	-8.9	3	II	57.9	38.9	60	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2219	NM_005450	Huesken	NOG	9241	ACGGGGCAGAAUGUCUGCGac	CGCAGACAUUCUGCCCCGU	-2.4	-2.2	-5.2	2	4	6	-43.2	43.5	7.7	1	II	63.2	52.6	53	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2220	NM_005450	Huesken	NOG	9241	CGGGGCAGAAUGUCUGCGAcc	UCGCAGACAUUCUGCCCCG	-2.4	-2.4	-5.2	-1	-3	6	-43.4	37.1	-5.8	0	III	63.2	34	47.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2221	NM_005450	Huesken	NOG	9241	GGCAGAAUGUCUGCGACCAca	UGGUCGCAGACAUUCUGCC	-2.1	-3.3	-5.2	1	-2	3	-42	40.3	-3.1	0	III	57.9	29.8	40.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2222	NM_005450	Huesken	NOG	9241	CAGAAUGUCUGCGACCACAgc	UGUGGUCGCAGACAUUCUG	-2.1	-2.1	-0.9	0	-3	3	-39.6	50.3	-5.4	4	II	52.6	45	57.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2223	NM_005450	Huesken	NOG	9241	UGUCUGCGACCACAGCCACau	GUGGCUGUGGUCGCAGACA	-2.2	-2.1	-5.8	1	3	3	-44.1	45	7.5	3	II	63.2	53.1	83.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2224	NM_005450	Huesken	NOG	9241	CUGCGACCACAGCCACAUCug	GAUGUGGCUGUGGUCGCAG	-2.4	-2.1	-6.8	0	-1	3	-43	38.7	10.1	-1	II	63.2	40.2	81.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2225	NM_005450	Huesken	NOG	9241	UAACUUCCUCCGCAGCUUCuu	GAAGCUGCGGAGGAAGUUA	-2.4	-1.3	-1.5	1	3	4	-39.7	66.5	7.5	6	Ia	52.6	68.8	102	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2226	NM_005450	Huesken	NOG	9241	UCCUCCGCAGCUUCUUGCUua	AGCAAGAAGCUGCGGAGGA	-2.1	-2.4	-2.5	0	1	4	-42.9	66.5	-3.3	3	II	57.9	51.6	97.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2227	NM_005450	Huesken	NOG	9241	CGCAGCUUCUUGCUUAGGCgc	GCCUAAGCAAGAAGCUGCG	-3.4	-2.4	-2.5	1	1	3	-40.4	59.5	10.1	0	II	57.9	46.6	85.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2228	NM_005450	Huesken	NOG	9241	GCUUCUUGCUUAGGCGCUGcu	CAGCGCCUAAGCAAGAAGC	-2.1	-3.4	-2.1	1	1	5	-40.4	46.1	0	1	II	57.9	39	62.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2229	NM_005450	Huesken	NOG	9241	CUUGCUUAGGCGCUGCUUCuu	GAAGCAGCGCCUAAGCAAG	-2.4	-2.1	-2.1	1	1	5	-40.4	63.4	7.8	2	II	57.9	55.1	83	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2230	NM_005450	Huesken	NOG	9241	UUAGGCGCUGCUUCUUGCCcu	GGCAAGAAGCAGCGCCUAA	-3.3	-0.9	-2.9	0	5	5	-41.6	65.5	8.1	4	II	57.9	73.2	91.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2231	NM_005450	Huesken	NOG	9241	UAGGCGCUGCUUCUUGCCCug	GGGCAAGAAGCAGCGCCUA	-3.3	-1.3	-4	1	5	5	-44	61.1	15.2	2	II	63.2	67.6	93.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2232	NM_005450	Huesken	NOG	9241	GCUUCUUGCCCUGGGCCAAgc	UUGGCCCAGGGCAAGAAGC	-0.9	-3.4	-2.7	1	-2	5	-44.4	42.1	-3.1	1	II	63.2	22.2	41.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2233	NM_005450	Huesken	NOG	9241	CAAGCCCUCGGAGAACUCUag	AGAGUUCUCCGAGGGCUUG	-2.1	-2.1	-4.5	0	-1	4	-41.9	44.8	-6	1	III	57.9	44	55.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2234	NM_005450	Huesken	NOG	9241	GAACUCUAGCCCUUUGAUCuc	GAUCAAAGGGCUAGAGUUC	-2.4	-2.4	-0.8	3	2	4	-37.4	68.8	5	4	II	47.4	52.2	78.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2235	NM_005450	Huesken	NOG	9241	UCUAGCCCUUUGAUCUCGCuc	GCGAGAUCAAAGGGCUAGA	-3.4	-2.4	0.4	0	5	4	-40.1	63.4	7.1	5	II	52.6	63.5	96.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2236	NM_005450	Huesken	NOG	9241	CCCCGACGGCCGCUGCCGCag	GCGGCAGCGGCCGUCGGGG	-3.4	-3.3	-7	1	1	7	-51.8	12.6	7.8	-2	II	89.5	28.4	70.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2237	NM_005450	Huesken	NOG	9241	CCGCUGCCGCAGCAGCUGGuc	CCAGCUGCUGCGGCAGCGG	-3.3	-3.3	-9.1	1	-1	5	-48.5	26.5	2.7	0	II	78.9	35.5	78.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2238	NM_005450	Huesken	NOG	9241	GCUGCCGCAGCAGCUGGUCca	GACCAGCUGCUGCGGCAGC	-2.4	-3.4	-7.4	0	1	5	-47.4	28.9	5.1	0	II	73.7	33.3	55.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2239	NM_005450	Huesken	NOG	9241	GCAGCAGCUGGUCCAGCUCcg	GAGCUGGACCAGCUGCUGC	-2.4	-3.4	-4.6	0	1	2	-46.1	36.1	12.8	0	II	68.4	37.6	71.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2240	NM_005450	Huesken	NOG	9241	GCUGGUCCAGCUCCGCCAGgu	CUGGCGGAGCUGGACCAGC	-2.1	-3.4	-2.7	0	1	5	-47.5	33.9	3.1	-1	II	73.7	30.7	58.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2241	NM_005450	Huesken	NOG	9241	GCGAGGUGGCCAUGAAGCCug	GGCUUCAUGGCCACCUCGC	-3.3	-3.4	-5.7	1	1	4	-45.3	29.3	5.1	0	II	68.4	39.6	64.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2242	NM_005450	Huesken	NOG	9241	UGGCCAUGAAGCCUGGGUCgu	GACCCAGGCUUCAUGGCCA	-2.4	-2.1	-5.9	2	3	4	-44.9	58.8	9.8	3	II	63.2	59.1	82.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2243	NM_005450	Huesken	NOG	9241	CCCGAGCAGCGAGCGCAGCag	GCUGCGCUCGCUGCUCGGG	-3.4	-3.3	-1.3	0	-1	4	-48.2	15.6	8.1	-1	II	78.9	32.4	67.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2244	NM_005450	Huesken	NOG	9241	GAGCAGCGAGCGCAGCAGCgu	GCUGCUGCGCUCGCUGCUC	-3.4	-2.4	-1.5	1	1	4	-46.8	26.1	10.2	0	II	73.7	39.4	78.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2245	NM_005450	Huesken	NOG	9241	AGCAGCGAGCGCAGCAGCGuc	CGCUGCUGCGCUCGCUGCU	-2.4	-2.1	-2.6	1	3	4	-46.8	29.9	-4.9	2	II	73.7	47.8	73.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2246	NM_005450	Huesken	NOG	9241	CAGCGAGCGCAGCAGCGUCuc	GACGCUGCUGCGCUCGCUG	-2.4	-2.1	-3.1	1	0	4	-45.9	27.3	10.1	0	II	73.7	40.9	70.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2247	NM_005450	Huesken	NOG	9241	GCGCAGCAGCGUCUCGUUCag	GAACGAGACGCUGCUGCGC	-2.4	-3.4	-3.1	2	0	4	-43.8	37.9	17.9	0	II	68.4	33.5	74.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2248	NM_005450	Huesken	NOG	9241	GCAGCAGCGUCUCGUUCAGau	CUGAACGAGACGCUGCUGC	-2.1	-3.4	-0.1	0	1	3	-42.2	34.1	3.1	1	II	63.2	26.9	46.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2249	NM_005450	Huesken	NOG	9241	GUUCAGAUCCUUUUCCUUGgg	CAAGGAAAAGGAUCUGAAC	-2.1	-2.2	0.1	2	2	2	-34.5	75.2	8.1	5	II	42.1	56.9	95.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2250	NM_005450	Huesken	NOG	9241	CCUUGGGGUCAAAGAUAGGgu	CCUAUCUUUGACCCCAAGG	-3.3	-3.3	-1.7	-2	0	4	-39.1	40.5	-2.3	2	II	52.6	39.9	89.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2251	NM_005450	Huesken	NOG	9241	GGGUCAAAGAUAGGGUCUGgg	CAGACCCUAUCUUUGACCC	-2.1	-3.3	0.6	0	0	3	-39.5	41.8	0	3	II	52.6	37.8	88.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2252	NM_005450	Huesken	NOG	9241	GGGUCUGGGUGUUCGAUGAgg	UCAUCGAACACCCAGACCC	-2.4	-3.3	1.5	1	-3	3	-42.2	55.8	-0.7	2	III	57.9	28.9	67.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2253	NM_005450	Huesken	NOG	9241	GUCUGGGUGUUCGAUGAGGuc	CCUCAUCGAACACCCAGAC	-3.3	-2.2	1.5	1	1	3	-41	42.6	-2.4	2	II	57.9	43.6	79.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2254	NM_005450	Huesken	NOG	9241	UCUGGGUGUUCGAUGAGGUcc	ACCUCAUCGAACACCCAGA	-2.2	-2.4	2	1	3	3	-41	54	-6.6	5	II	52.6	56	101.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2255	NM_005450	Huesken	NOG	9241	UGUUCGAUGAGGUCCACCAgg	UGGUGGACCUCAUCGAACA	-2.1	-2.1	-2.3	1	1	2	-41	71	-3.8	6	II	52.6	61	96.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2256	NM_005450	Huesken	NOG	9241	UUCGAUGAGGUCCACCAGGgg	CCUGGUGGACCUCAUCGAA	-3.3	-0.9	-2.4	1	3	2	-42.1	51.6	2.8	4	Ib	57.9	70.5	81.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2257	NM_005450	Huesken	NOG	9241	GGGGCAGGUUGUCGCUGGGug	CCCAGCGACAACCUGCCCC	-3.3	-3.3	-0.9	-1	1	5	-47.2	28	5.4	0	II	73.7	27.9	68.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2258	NM_005450	Huesken	NOG	9241	UUGUCGCUGGGUGCCGGGCgg	GCCCGGCACCCAGCGACAA	-3.4	-0.9	-1	1	4	7	-47.6	50.7	10.4	3	II	73.7	61	88.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2259	NM_005450	Huesken	NOG	9241	UCGCUGGGUGCCGGGCGGAug	UCCGCCCGGCACCCAGCGA	-2.4	-2.4	-1.7	0	0	9	-50.5	15.5	-8.5	3	II	78.9	39.1	72	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2260	NM_005450	Huesken	NOG	9241	CGCUGGGUGCCGGGCGGAUgu	AUCCGCCCGGCACCCAGCG	-1.1	-2.4	-1	-1	-3	9	-49.2	12.9	-8.3	0	III	78.9	17.3	42.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2261	NM_005450	Huesken	NOG	9241	GGGUGCCGGGCGGAUGUGGag	CCACAUCCGCCCGGCACCC	-3.3	-3.3	-0.2	1	0	9	-48.9	22.5	-2.4	1	II	78.9	29.2	51.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2262	NM_005450	Huesken	NOG	9241	GCCGGGCGGAUGUGGAGAUag	AUCUCCACAUCCGCCCGGC	-1.1	-3.4	-0.2	0	-2	9	-46	20.3	-4	0	III	68.4	18.7	60.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2263	NM_005450	Huesken	NOG	9241	GGGCGGAUGUGGAGAUAGUgc	ACUAUCUCCACAUCCGCCC	-2.2	-3.3	4.4	1	-2	6	-42.5	29.8	-6.6	0	III	57.9	26.3	52.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2264	NM_005450	Huesken	NOG	9241	GGAGAUAGUGCUGGCCGCCgg	GGCGGCCAGCACUAUCUCC	-3.3	-3.3	-1.7	-1	2	7	-45.7	30.8	10.8	1	II	68.4	44.6	87.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2265	NM_005450	Huesken	NOG	9241	GAUAGUGCUGGCCGCCGGCcg	GCCGGCGGCCAGCACUAUC	-3.4	-2.4	-1.8	-1	3	10	-47	37.7	7.5	2	II	73.7	45.2	82.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2266	NM_007019	Huesken	UBE2C	11065	UUCCAGAGCUCGGCAGCAUgu	AUGCUGCCGAGCUCUGGAA	-1.1	-0.9	-1.8	2	1	4	-43.1	42.6	-3.6	4	II	57.9	50.1	84.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2267	NM_007019	Huesken	UBE2C	11065	UCCAGAGCUCGGCAGCAUGug	CAUGCUGCCGAGCUCUGGA	-2.1	-2.4	-1.8	0	1	4	-44.3	45.1	2.4	3	II	63.2	53.7	90.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2268	NM_007019	Huesken	UBE2C	11065	AGCUCGGCAGCAUGUGUGUuc	ACACACAUGCUGCCGAGCU	-2.2	-2.1	-1.8	0	0	4	-42.8	48.8	-6.3	3	II	57.9	39.8	78	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2269	NM_007019	Huesken	UBE2C	11065	CUCGGCAGCAUGUGUGUUCaa	GAACACACAUGCUGCCGAG	-2.4	-2.1	2.4	-1	-1	4	-40.6	51.5	5.4	3	II	57.9	49.3	89.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2270	NM_007019	Huesken	UBE2C	11065	UCGGCAGCAUGUGUGUUCAag	UGAACACACAUGCUGCCGA	-2.1	-2.4	2.1	0	0	4	-40.6	58.7	1.6	5	II	52.6	47.5	86.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2271	NM_007019	Huesken	UBE2C	11065	AUGUGUGUUCAAGGGACUAuc	UAGUCCCUUGAACACACAU	-1.3	-1.1	1.6	0	0	3	-37	56.5	-1.5	5	II	42.1	48.4	76.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2272	NM_007019	Huesken	UBE2C	11065	UUCAAGGGACUAUCAAUGUug	ACAUUGAUAGUCCCUUGAA	-2.2	-0.9	1.9	0	1	3	-34.9	70.3	-1.3	8	II	36.8	65	90.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2273	NM_007019	Huesken	UBE2C	11065	UCAAGGGACUAUCAAUGUUgg	AACAUUGAUAGUCCCUUGA	-0.9	-2.4	1.9	1	1	3	-34.9	65.2	3.8	6	II	36.8	56.1	93.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2274	NM_007019	Huesken	UBE2C	11065	CUAUCAAUGUUGGGUUCUCcu	GAGAACCCAACAUUGAUAG	-2.4	-2.1	1.8	-1	1	3	-34.9	59.9	5.4	4	II	42.1	49.2	66.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2275	NM_007019	Huesken	UBE2C	11065	AUCAAUGUUGGGUUCUCCUag	AGGAGAACCCAACAUUGAU	-2.1	-1.1	-1.1	1	3	3	-36.9	78.7	1.1	5	II	42.1	63.1	94.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2276	NM_007019	Huesken	UBE2C	11065	AAUGUUGGGUUCUCCUAGAag	UCUAGGAGAACCCAACAUU	-2.4	-0.9	-1.1	2	1	3	-37.1	66.7	-6.1	5	II	42.1	54	88.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2277	NM_007019	Huesken	UBE2C	11065	UGUUGGGUUCUCCUAGAAGgc	CUUCUAGGAGAACCCAACA	-2.1	-2.1	-1.1	0	3	3	-38.1	66.3	2.4	5	II	47.4	59.3	86.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2278	NM_007019	Huesken	UBE2C	11065	UUGGGUUCUCCUAGAAGGCuc	GCCUUCUAGGAGAACCCAA	-3.4	-0.9	-1.1	0	4	3	-40.5	60.6	5.5	4	Ib	52.6	70.4	92.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2279	NM_007019	Huesken	UBE2C	11065	GUUCUCCUAGAAGGCUCUGga	CAGAGCCUUCUAGGAGAAC	-2.1	-2.2	-0.9	0	2	3	-39.6	51	2.3	3	II	52.6	41.2	75.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2280	NM_007019	Huesken	UBE2C	11065	UCCUAGAAGGCUCUGGAUGga	CAUCCAGAGCCUUCUAGGA	-2.1	-2.4	-0.7	1	2	3	-40.9	62.7	8.1	6	Ib	52.6	59.5	78.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2281	NM_007019	Huesken	UBE2C	11065	UAGAAGGCUCUGGAUGGAGag	CUCCAUCCAGAGCCUUCUA	-2.1	-1.3	-0.5	0	3	3	-40.9	51.4	2.7	7	Ib	52.6	62.2	81.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2282	NM_007019	Huesken	UBE2C	11065	CUGGAUGGAGAGCAGAAUGgu	CAUUCUGCUCUCCAUCCAG	-2.1	-2.1	1.4	-1	-1	2	-39.5	50.7	5.4	3	II	52.6	51.5	79.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2283	NM_007019	Huesken	UBE2C	11065	GGAGAGCAGAAUGGUCCUGac	CAGGACCAUUCUGCUCUCC	-2.1	-3.3	-1.2	0	1	2	-41.8	35	8	1	II	57.9	36.2	45.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2284	NM_007019	Huesken	UBE2C	11065	AGCAGAAUGGUCCUGACAUca	AUGUCAGGACCAUUCUGCU	-1.1	-2.1	-1.3	2	1	2	-39.4	56.4	-1.6	3	II	47.4	45.8	56.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2285	NM_007019	Huesken	UBE2C	11065	GCAGAAUGGUCCUGACAUCau	GAUGUCAGGACCAUUCUGC	-2.4	-3.4	-1.3	1	0	2	-39.7	39.1	5.4	2	II	52.6	37.3	48.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2286	NM_007019	Huesken	UBE2C	11065	GAAUGGUCCUGACAUCAUAca	UAUGAUGUCAGGACCAUUC	-1.3	-2.4	0.6	2	-2	2	-36.6	58.2	-1.4	4	II	42.1	39.6	32.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2287	NM_007019	Huesken	UBE2C	11065	GGUCCUGACAUCAUACAGGgc	CCUGUAUGAUGUCAGGACC	-3.3	-3.3	-4.5	2	2	2	-39.8	55.6	-2.6	2	II	52.6	49.4	42	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2288	NM_007019	Huesken	UBE2C	11065	CCUGACAUCAUACAGGGCAga	UGCCCUGUAUGAUGUCAGG	-2.1	-3.3	-3.7	0	-2	4	-40.7	47.1	-0.7	3	III	52.6	42.6	50.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2289	NM_007019	Huesken	UBE2C	11065	ACAUCAUACAGGGCAGACCac	GGUCUGCCCUGUAUGAUGU	-3.3	-2.2	-0.7	3	3	4	-40.8	61.1	7.4	6	Ia	52.6	60.8	55.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2290	NM_007019	Huesken	UBE2C	11065	CAUCAUACAGGGCAGACCAcu	UGGUCUGCCCUGUAUGAUG	-2.1	-2.1	-0.7	0	-1	4	-40.7	53.2	-0.7	4	II	52.6	46.6	28.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2291	NM_007019	Huesken	UBE2C	11065	UCAUACAGGGCAGACCACUuu	AGUGGUCUGCCCUGUAUGA	-2.1	-2.4	-0.7	1	1	4	-41.8	47.9	-3.6	7	II	52.6	60.4	61.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2292	NM_007019	Huesken	UBE2C	11065	GGCAGACCACUUUUCCUUCag	GAAGGAAAAGUGGUCUGCC	-2.4	-3.3	0.1	0	0	3	-39	59.2	12.8	2	II	52.6	39.2	63.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2293	NM_007019	Huesken	UBE2C	11065	GACCACUUUUCCUUCAGGAug	UCCUGAAGGAAAAGUGGUC	-2.4	-2.4	-2.1	2	0	2	-38	62.9	-3.4	2	III	47.4	38.6	71.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2294	NM_007019	Huesken	UBE2C	11065	CACUUUUCCUUCAGGAUGUcc	ACAUCCUGAAGGAAAAGUG	-2.2	-2.1	-2.4	0	-2	2	-35.5	70	-10.9	4	II	42.1	48.5	46.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2295	NM_007019	Huesken	UBE2C	11065	UUCCUUCAGGAUGUCCAGGca	CCUGGACAUCCUGAAGGAA	-3.3	-0.9	-2.4	2	4	2	-40.5	68.4	7.7	4	Ib	52.6	67.1	74.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2296	NM_007019	Huesken	UBE2C	11065	UCCUUCAGGAUGUCCAGGCau	GCCUGGACAUCCUGAAGGA	-3.4	-2.4	-1.6	1	3	3	-43	65.4	7.4	5	Ib	57.9	66.7	85.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2297	NM_007019	Huesken	UBE2C	11065	CCUUCAGGAUGUCCAGGCAua	UGCCUGGACAUCCUGAAGG	-2.1	-3.3	-1	-1	-2	3	-42.7	46.7	-0.3	1	III	57.9	27.3	49.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2298	NM_007019	Huesken	UBE2C	11065	AGGAUGUCCAGGCAUAUGUua	ACAUAUGCCUGGACAUCCU	-2.2	-2.1	-1	3	0	3	-39.7	69.7	-1.6	6	II	47.4	56.9	75.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2299	NM_007019	Huesken	UBE2C	11065	GGCAUAUGUUACCCUGGGUgu	ACCCAGGGUAACAUAUGCC	-2.2	-3.3	-1.5	1	-1	3	-40.6	54.7	-1.6	2	II	52.6	32.2	39.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2300	NM_007019	Huesken	UBE2C	11065	UUACCCUGGGUGUCCACGUug	ACGUGGACACCCAGGGUAA	-2.2	-0.9	-1.8	3	3	3	-42.9	60.5	-4	4	II	57.9	66.4	83	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2301	NM_007019	Huesken	UBE2C	11065	GGGUGUCCACGUUGGGGUGau	CACCCCAACGUGGACACCC	-2.1	-3.3	-1.1	-1	0	4	-44.9	41.8	3	-1	II	68.4	28.3	11.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2302	NM_007019	Huesken	UBE2C	11065	GUCCACGUUGGGGUGAUAGca	CUAUCACCCCAACGUGGAC	-2.1	-2.2	-1.9	1	1	4	-40.9	51.6	5	2	II	57.9	40.6	77.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2303	NM_007019	Huesken	UBE2C	11065	UCCACGUUGGGGUGAUAGCag	GCUAUCACCCCAACGUGGA	-3.4	-2.4	-1.9	1	2	4	-42.1	60.6	7.4	3	II	57.9	58.2	89.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2304	NM_007019	Huesken	UBE2C	11065	CGUUGGGGUGAUAGCAGGGcg	CCCUGCUAUCACCCCAACG	-3.3	-2.4	2.9	-2	1	4	-42.9	39.5	0.7	2	II	63.2	42.2	53.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2305	NM_007019	Huesken	UBE2C	11065	GUUGGGGUGAUAGCAGGGCgu	GCCCUGCUAUCACCCCAAC	-3.4	-2.2	1.1	1	3	4	-43.9	35.2	7.4	3	II	63.2	49.3	63.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2306	NM_007019	Huesken	UBE2C	11065	UAGCAGGGCGUGAGGAACUuc	AGUUCCUCACGCCCUGCUA	-2.1	-1.3	0.8	1	1	5	-43.1	41	-3.9	5	II	57.9	60.7	84.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2307	NM_007019	Huesken	UBE2C	11065	AGCAGGGCGUGAGGAACUUca	AAGUUCCUCACGCCCUGCU	-0.9	-2.1	0.8	1	0	5	-42.7	29.9	-4	3	II	57.9	36	51	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2308	NM_007019	Huesken	UBE2C	11065	GCAGGGCGUGAGGAACUUCac	GAAGUUCCUCACGCCCUGC	-2.4	-3.4	0.8	0	0	5	-43	26.8	9.7	1	II	63.2	36.9	40.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2309	NM_007019	Huesken	UBE2C	11065	GUGAGGAACUUCACUGUGGgc	CCACAGUGAAGUUCCUCAC	-3.3	-2.2	-2	1	1	2	-39.1	51.9	-4.9	3	II	52.6	52.3	74.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2310	NM_007019	Huesken	UBE2C	11065	GAGGAACUUCACUGUGGGCgc	GCCCACAGUGAAGUUCCUC	-3.4	-2.4	1.8	-1	2	4	-41.5	45.5	10.1	1	II	57.9	39.2	46.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2311	NM_007019	Huesken	UBE2C	11065	GGAACUUCACUGUGGGCGCau	GCGCCCACAGUGAAGUUCC	-3.4	-3.3	-0.6	0	2	6	-42.8	50.7	7.4	2	II	63.2	45.1	70.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2312	NM_007019	Huesken	UBE2C	11065	ACUUCACUGUGGGCGCAUUgu	AAUGCGCCCACAGUGAAGU	-0.9	-2.2	-0.6	2	0	6	-40.3	52.5	-4	4	II	52.6	35.9	57.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2313	NM_007019	Huesken	UBE2C	11065	UUCACUGUGGGCGCAUUGUaa	ACAAUGCGCCCACAGUGAA	-2.2	-0.9	-0.6	1	1	6	-40.3	66.6	-6.3	7	II	52.6	60.2	93.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2314	NM_007019	Huesken	UBE2C	11065	GUGGGCGCAUUGUAAGGGUag	ACCCUUACAAUGCGCCCAC	-2.2	-2.2	2.5	0	0	6	-41.6	38.3	-4	1	III	57.9	36.4	47.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2315	NM_007019	Huesken	UBE2C	11065	CGCAUUGUAAGGGUAGCCAcu	UGGCUACCCUUACAAUGCG	-2.1	-2.4	-0.4	-1	-2	3	-39.5	56.1	-3.4	4	III	52.6	39.3	61.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2316	NM_007019	Huesken	UBE2C	11065	GCAUUGUAAGGGUAGCCACug	GUGGCUACCCUUACAAUGC	-2.2	-3.4	-0.2	1	1	3	-39.3	56.9	7.4	4	II	52.6	44.4	87.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2317	NM_007019	Huesken	UBE2C	11065	CAUUGUAAGGGUAGCCACUgg	AGUGGCUACCCUUACAAUG	-2.1	-2.1	-0.4	-1	-1	3	-38	59	-5.5	4	II	47.4	48.9	76.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2318	NM_007019	Huesken	UBE2C	11065	UGUAAGGGUAGCCACUGGGga	CCCAGUGGCUACCCUUACA	-3.3	-2.1	-0.4	0	4	3	-42.6	57.1	2.8	7	Ib	57.9	65.4	85.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2319	NM_007019	Huesken	UBE2C	11065	GUAAGGGUAGCCACUGGGGaa	CCCCAGUGGCUACCCUUAC	-3.3	-2.2	0.4	0	3	4	-43.8	41	-7.3	3	II	63.2	49.3	67.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2320	NM_007019	Huesken	UBE2C	11065	GUAGCCACUGGGGAACUCUag	AGAGUUCCCCAGUGGCUAC	-2.1	-2.2	0.2	0	0	4	-42.8	45.3	-4	3	III	57.9	45.8	87	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2321	NM_007019	Huesken	UBE2C	11065	UAGCCACUGGGGAACUCUAgc	UAGAGUUCCCCAGUGGCUA	-1.3	-1.3	0.2	2	0	4	-41.9	51.2	-6.3	4	II	52.6	50	67.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2322	NM_007019	Huesken	UBE2C	11065	GCCACUGGGGAACUCUAGCga	GCUAGAGUUCCCCAGUGGC	-3.4	-3.4	-0.1	1	1	4	-44	49.4	14.4	1	II	63.2	41.8	69	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2323	NM_007019	Huesken	UBE2C	11065	CCACUGGGGAACUCUAGCGag	CGCUAGAGUUCCCCAGUGG	-2.4	-3.3	-1.1	1	1	4	-43	45.6	-2.1	2	II	63.2	50.1	86.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2324	NM_007019	Huesken	UBE2C	11065	GAACUCUAGCGAGAGCUUAua	UAAGCUCUCGCUAGAGUUC	-1.3	-2.4	-4	3	-2	3	-38	50.2	-3.8	4	II	47.4	38.2	60.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2325	NM_007019	Huesken	UBE2C	11065	UCUAGCGAGAGCUUAUACCuc	GGUAUAAGCUCUCGCUAGA	-3.3	-2.4	-1.8	1	4	3	-38.3	75.1	7.4	6	II	47.4	70	91.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2326	NM_007019	Huesken	UBE2C	11065	CUAGCGAGAGCUUAUACCUca	AGGUAUAAGCUCUCGCUAG	-2.1	-2.1	-1.8	-1	0	3	-38	59.6	-5.3	2	III	47.4	53.8	92.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2327	NM_007019	Huesken	UBE2C	11065	AGCGAGAGCUUAUACCUCAgg	UGAGGUAUAAGCUCUCGCU	-2.1	-2.1	-2.1	2	-1	3	-39.1	49.6	-1.1	4	II	47.4	50	80.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2328	NM_007019	Huesken	UBE2C	11065	GCGAGAGCUUAUACCUCAGgu	CUGAGGUAUAAGCUCUCGC	-2.1	-3.4	-2.1	0	0	3	-39.1	48.1	2.7	1	II	52.6	36.2	75.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2329	NM_007019	Huesken	UBE2C	11065	GAGAGCUUAUACCUCAGGUcu	ACCUGAGGUAUAAGCUCUC	-2.2	-2.4	-1.2	1	1	2	-38.8	67	0.7	2	III	47.4	44.3	80.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2330	NM_007019	Huesken	UBE2C	11065	GAGCUUAUACCUCAGGUCUuc	AGACCUGAGGUAUAAGCUC	-2.1	-2.4	-0.4	1	-1	2	-38.8	66.4	-0.9	4	II	47.4	47.5	71.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2331	NM_007019	Huesken	UBE2C	11065	AGCUUAUACCUCAGGUCUUca	AAGACCUGAGGUAUAAGCU	-0.9	-2.1	-0.4	2	0	2	-37.3	60.3	-8.9	5	II	42.1	46.1	46.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2332	NM_007019	Huesken	UBE2C	11065	CCUCAGGUCUUCAUAUACUgu	AGUAUAUGAAGACCUGAGG	-2.1	-3.3	1.8	1	-1	2	-36.5	55.3	-5.9	3	III	42.1	43.8	77.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2333	NM_007019	Huesken	UBE2C	11065	CUCAGGUCUUCAUAUACUGuu	CAGUAUAUGAAGACCUGAG	-2.1	-2.1	0.3	0	0	2	-35.3	64.8	-4.4	3	II	42.1	54.6	82.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2334	NM_007019	Huesken	UBE2C	11065	UCAGGUCUUCAUAUACUGUuc	ACAGUAUAUGAAGACCUGA	-2.2	-2.4	-0.2	0	2	2	-35.4	74.3	1.1	5	II	36.8	60.4	88.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2335	NM_007019	Huesken	UBE2C	11065	AGGUCUUCAUAUACUGUUCca	GAACAGUAUAUGAAGACCU	-2.4	-2.1	0.8	2	1	2	-34.2	87.9	10.1	5	Ib	36.8	59.9	86.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2336	NM_007019	Huesken	UBE2C	11065	CUUCAUAUACUGUUCCAGCug	GCUGGAACAGUAUAUGAAG	-3.4	-2.1	-1.2	0	2	2	-35.1	75.2	10.4	3	II	42.1	61.9	90.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2337	NM_007019	Huesken	UBE2C	11065	UUCAUAUACUGUUCCAGCUgc	AGCUGGAACAGUAUAUGAA	-2.1	-0.9	-1.5	2	2	2	-35.1	89.4	-1	6	II	36.8	69.4	97.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2338	NM_007019	Huesken	UBE2C	11065	UAUACUGUUCCAGCUGCUCca	GAGCAGCUGGAACAGUAUA	-2.4	-1.3	-1.5	0	4	2	-38.6	73.1	5.1	6	Ia	47.4	70.8	85.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2339	NM_007019	Huesken	UBE2C	11065	ACUGUUCCAGCUGCUCCAUgg	AUGGAGCAGCUGGAACAGU	-1.1	-2.2	-0.8	1	1	2	-41.4	53.8	-3.3	4	II	52.6	40.7	84.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2340	NM_007019	Huesken	UBE2C	11065	CCAGCUGCUCCAUGGAUGGuc	CCAUCCAUGGAGCAGCUGG	-3.3	-3.3	-1.2	-2	0	2	-43.8	41.8	-4.4	1	II	63.2	43.5	80.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2341	NM_007019	Huesken	UBE2C	11065	CAGCUGCUCCAUGGAUGGUcc	ACCAUCCAUGGAGCAGCUG	-2.2	-2.1	-1.7	0	-1	2	-42.7	42.3	-0.7	0	III	57.9	33.1	62.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2342	NM_002559	Huesken	P2RX3	5024	UGGGUUGGUCAAAGCCGCGau	CGCGGCUUUGACCAACCCA	-2.4	-2.1	-1	-1	3	6	-42.7	43.6	-0.3	3	II	63.2	62.5	84.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2343	NM_002559	Huesken	P2RX3	5024	CACUCCCACAGAAGUAAAGgc	CUUUACUUCUGUGGGAGUG	-2.1	-2.1	-4	-1	-1	3	-36.7	60	-4.6	2	II	47.4	41	67.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2344	NM_002559	Huesken	P2RX3	5024	AAGCCUUCAGGAGGGUGCGgu	CGCACCCUCCUGAAGGCUU	-2.4	-0.9	-0.7	2	4	3	-43.8	48.6	0	3	Ib	63.2	56.4	67.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2345	NM_002559	Huesken	P2RX3	5024	AACCUGAAGUUGUAGCCUGgg	CAGGCUACAACUUCAGGUU	-2.1	-0.9	0.9	3	3	3	-37.7	57.9	0	5	Ib	47.4	60.2	95.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2346	NM_002559	Huesken	P2RX3	5024	AAACGCUGUCGAGCCGGGUga	ACCCGGCUCGACAGCGUUU	-2.2	-0.9	-1.7	3	3	6	-43.4	40.2	-4	3	II	63.2	50.2	94.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2347	NM_002559	Huesken	P2RX3	5024	UCGAGCCGGGUGAAGGAGUau	ACUCCUUCACCCGGCUCGA	-2.2	-2.4	0.7	1	0	6	-44.7	36.7	-6.6	3	II	63.2	49.4	80.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2348	NM_002559	Huesken	P2RX3	5024	CCCAGGCCUUGUCCAAGUCgc	GACUUGGACAAGGCCUGGG	-2.4	-3.3	-0.5	-1	-1	4	-43.5	42.1	10.8	0	II	63.2	35	93	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2349	NM_002559	Huesken	P2RX3	5024	UUGACCACGUCCCCUACCCgc	GGGUAGGGGACGUGGUCAA	-3.3	-0.9	-0.6	1	4	4	-44.3	63.5	5.1	5	Ib	63.2	72	94.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2350	NM_002559	Huesken	P2RX3	5024	AGAUGGGGCAGAAAGGGUCcu	GACCCUUUCUGCCCCAUCU	-2.4	-2.1	1.8	2	3	5	-42.7	45.1	4.8	5	II	57.9	57.6	65.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2351	NM_002559	Huesken	P2RX3	5024	UGUCCGGGUGGAAGCGGCAgg	UGCCGCUUCCACCCGGACA	-2.1	-2.1	-2.1	0	1	5	-46.6	31.3	-6.3	3	II	68.4	46.4	93.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2352	NM_002559	Huesken	P2RX3	5024	AACGGAUGCUGUUCUUGAUga	AUCAAGAACAGCAUCCGUU	-1.1	-0.9	1.2	3	1	3	-36.1	69.1	-1	4	II	42.1	44.5	70.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2353	NM_002559	Huesken	P2RX3	5024	UUGAUGAAAAUAGUGAAGUuc	ACUUCACUAUUUUCAUCAA	-2.2	-0.9	4.6	0	2	1	-30.1	83	-1.6	8	II	26.3	75.1	92.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2354	NM_002559	Huesken	P2RX3	5024	CAUCAUGAUGGGCGUUUCCac	GGAAACGCCCAUCAUGAUG	-3.3	-2.1	-1.1	-1	1	5	-38.6	57.8	10.5	4	II	52.6	51.7	74.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2355	NM_002559	Huesken	P2RX3	5024	GUUUCCACUGUGUCCACCUcc	AGGUGGACACAGUGGAAAC	-2.1	-2.2	0.3	0	1	2	-40.1	65.8	-4	4	II	52.6	51.2	91.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2356	NM_002559	Huesken	P2RX3	5024	CCACCUCCGUGGGGCACCAgc	UGGUGCCCCACGGAGGUGG	-2.1	-3.3	-3.9	0	-2	5	-48.4	20.9	-5.8	-1	III	73.7	25.1	13.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2357	NM_002559	Huesken	P2RX3	5024	GCCCGCACUGGCUGUCUGAua	UCAGACAGCCAGUGCGGGC	-2.4	-3.4	-2.9	0	-3	6	-46.4	31.2	-6.1	0	III	68.4	22.4	23.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2358	NM_002559	Huesken	P2RX3	5024	ACACAGCGGUAUUUCUCCUca	AGGAGAAAUACCGCUGUGU	-2.1	-2.2	-0.4	3	3	4	-38.5	59.2	6.4	4	II	47.4	48.9	71.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2359	NM_002559	Huesken	P2RX3	5024	CACAGCGGUAUUUCUCCUCac	GAGGAGAAAUACCGCUGUG	-2.4	-2.1	-0.4	-1	0	4	-38.7	62.8	8.4	4	II	52.6	53.7	67.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2360	NM_002559	Huesken	P2RX3	5024	CCUCACUCUCUGGGCAGAAuc	UUCUGCCCAGAGAGUGAGG	-0.9	-3.3	-1	0	-3	4	-42.8	33	-3.1	1	III	57.9	25.1	44.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2361	NM_002559	Huesken	P2RX3	5024	UCACUCUCUGGGCAGAAUCcu	GAUUCUGCCCAGAGAGUGA	-2.4	-2.4	-2.4	2	2	4	-40.9	65.3	9.8	5	Ib	52.6	66.8	96.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2362	NM_002559	Huesken	P2RX3	5024	UCUCUGGGCAGAAUCCUUGca	CAAGGAUUCUGCCCAGAGA	-2.1	-2.4	-1.3	2	3	4	-40.5	62.9	-0.3	7	II	52.6	67.1	101.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2363	NM_002559	Huesken	P2RX3	5024	AGAAUCCUUGCAUCUGAUUuu	AAUCAGAUGCAAGGAUUCU	-0.9	-2.1	1	1	0	2	-34.9	71.8	-6.3	5	II	36.8	50.1	79.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2364	NM_002559	Huesken	P2RX3	5024	UCAGUAACAAUCAUCUUGGug	CCAAGAUGAUUGUUACUGA	-3.3	-2.4	0.6	0	4	2	-33.7	77.2	-2.6	8	Ia	36.8	75.2	98.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2365	NM_002559	Huesken	P2RX3	5024	AUGACAAAGACCGAGGUGCcc	GCACCUCGGUCUUUGUCAU	-3.4	-1.1	0.6	2	3	3	-39.6	58.3	2.7	7	Ia	52.6	65.3	85.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2366	NM_002559	Huesken	P2RX3	5024	GAGGUGCCCUGAGGUGGCGuc	CGCCACCUCAGGGCACCUC	-2.4	-2.4	-4.2	0	2	4	-47.5	26	0	0	II	73.7	36.1	13	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2367	NM_002559	Huesken	P2RX3	5024	GGCGUCACGUAAUCAGACAca	UGUCUGAUUACGUGACGCC	-2.1	-3.3	-1.9	1	-3	4	-39.2	48.6	-1.5	1	III	52.6	31.5	43.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2368	NM_002559	Huesken	P2RX3	5024	GUCACGUAAUCAGACACAUcc	AUGUGUCUGAUUACGUGAC	-1.1	-2.2	-1.9	1	-1	2	-35.5	55	-6.3	2	III	42.1	39.1	33.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2369	NM_002559	Huesken	P2RX3	5024	CAUGACUCUGUUGGCGUAGag	CUACGCCAACAGAGUCAUG	-2.1	-2.1	1.7	-1	0	4	-38.5	54.3	3.7	5	II	52.6	46.9	53.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2370	NM_002559	Huesken	P2RX3	5024	AAUGGCUGUGUCCCGUACCug	GGUACGGGACACAGCCAUU	-3.3	-0.9	-1.5	2	4	4	-41.9	59.9	7.5	3	Ib	57.9	66.4	61.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2371	NM_002559	Huesken	P2RX3	5024	UGCAAGAAAACCCACCCUAca	UAGGGUGGGUUUUCUUGCA	-1.3	-2.1	-2.6	0	-1	3	-38.8	55.8	-3.4	6	II	47.4	55.6	82.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2372	NM_002559	Huesken	P2RX3	5024	GAGAUGAUCAGAAGCUGAAcu	UUCAGCUUCUGAUCAUCUC	-0.9	-2.4	-1.2	0	-2	2	-36.5	56.4	-6.3	4	II	42.1	37.8	46.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2373	NM_002559	Huesken	P2RX3	5024	CUGAACUACUCGGUUGAUGau	CAUCAACCGAGUAGUUCAG	-2.1	-2.1	1.1	1	0	3	-36.3	63	0.7	4	II	47.4	50.8	74.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2374	NM_002559	Huesken	P2RX3	5024	CUCGGUUGAUGAUCCCGAUgg	AUCGGGAUCAUCAACCGAG	-1.1	-2.1	-4.7	0	-2	4	-39.4	52.9	-6	1	III	52.6	37.9	39.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2375	NM_002559	Huesken	P2RX3	5024	GGUUGAUGAUCCCGAUGGUcc	ACCAUCGGGAUCAUCAACC	-2.2	-3.3	-0.7	0	0	4	-40.1	43.9	-6.3	3	II	52.6	25.8	25.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2376	NM_002559	Huesken	P2RX3	5024	CUCUUCACAACCACCGACUug	AGUCGGUGGUUGUGAAGAG	-2.1	-2.1	1.3	-1	-2	3	-39.4	62.8	-13.3	5	II	52.6	51.8	64.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2377	NM_002559	Huesken	P2RX3	5024	CGGUGGACUGCUUCUCCGCug	GCGGAGAAGCAGUCCACCG	-3.4	-2.4	-2	-1	0	4	-44.5	45.8	6.1	0	II	68.4	46.4	81.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2378	NM_002559	Huesken	P2RX3	5024	GACUGCUUCUCCGCUGUGGuc	CCACAGCGGAGAAGCAGUC	-3.3	-2.4	-2.1	2	1	4	-43	54.6	-4.7	2	II	63.2	43.1	62.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2379	NM_002559	Huesken	P2RX3	5024	GCGAUUUUCAGCGUAGUCUca	AGACUACGCUGAAAAUCGC	-2.1	-3.4	0.5	2	-1	3	-36.7	69.9	-4	5	II	47.4	47.4	77.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2380	NM_002559	Huesken	P2RX3	5024	CAGCGUAGUCUCAUUCACCuc	GGUGAAUGAGACUACGCUG	-3.3	-2.1	-0.8	0	1	3	-38.8	55.3	2.8	2	II	52.6	59.3	87.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2381	NM_002559	Huesken	P2RX3	5024	AACUUCUUGGCUUUGUACUgg	AGUACAAAGCCAAGAAGUU	-2.1	-0.9	1.5	3	2	3	-34.1	93.2	-1	6	II	36.8	61.5	99.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2382	NM_002559	Huesken	P2RX3	5024	UUCUUGGCUUUGUACUGGUcg	ACCAGUACAAAGCCAAGAA	-2.2	-0.9	1.6	0	2	3	-36.5	72.9	-4	7	II	42.1	63.5	82.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2383	NM_002559	Huesken	P2RX3	5024	GGCUUUGUACUGGUCGGCCcc	GGCCGACCAGUACAAAGCC	-3.3	-3.3	-0.9	0	2	5	-42.9	51.8	9.7	2	II	63.2	44.7	68	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2384	NM_002559	Huesken	P2RX3	5024	UUGAGGAAGUUGAGCAGGAug	UCCUGCUCAACUUCCUCAA	-2.4	-0.9	3.6	0	1	2	-39.2	47.6	-6.3	6	II	47.4	57.5	90.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2385	NM_002559	Huesken	P2RX3	5024	UCCCACAGAAGUAAAGGCCgc	GGCCUUUACUUCUGUGGGA	-3.3	-2.4	-1	1	3	4	-40.3	59	10.5	5	II	52.6	65.5	80.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2386	NM_002559	Huesken	P2RX3	5024	CCACAGAAGUAAAGGCCGCca	GCGGCCUUUACUUCUGUGG	-3.4	-3.3	-0.3	0	1	6	-40.4	30.6	7.8	2	II	57.9	44.2	61.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2387	NM_002559	Huesken	P2RX3	5024	GAUGAUGGUGGGGAUGAUGuu	CAUCAUCCCCACCAUCAUC	-2.1	-2.4	4.8	0	1	4	-39.9	48	2.7	4	II	52.6	46	38.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2388	NM_002559	Huesken	P2RX3	5024	CUUCAGGAGGGUGCGGUACuc	GUACCGCACCCUCCUGAAG	-2.2	-2.1	1.7	1	0	4	-43.1	43.6	11.1	4	II	63.2	44.1	37.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2389	NM_002559	Huesken	P2RX3	5024	GGGACACGCUGCUUUUCUCag	GAGAAAAGCAGCGUGUCCC	-2.4	-3.3	1.4	1	1	3	-40.6	56.1	7.4	0	II	57.9	35.4	68.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2390	NM_002559	Huesken	P2RX3	5024	UCUCAGAAACGCUGUCGAGcc	CUCGACAGCGUUUCUGAGA	-2.1	-2.4	-1	0	3	3	-39	53	0.4	5	Ib	52.6	52.2	64.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2391	NM_002559	Huesken	P2RX3	5024	CAGAAACGCUGUCGAGCCGgg	CGGCUCGACAGCGUUUCUG	-2.4	-2.1	-1.7	-1	1	4	-41.2	40.7	6.1	1	II	63.2	40.8	86	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2392	NM_002559	Huesken	P2RX3	5024	AGAAACGCUGUCGAGCCGGgu	CCGGCUCGACAGCGUUUCU	-3.3	-2.1	-1.7	1	4	5	-42.4	39.3	0.4	4	Ib	63.2	58.2	98	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2393	NM_002559	Huesken	P2RX3	5024	AGGAGUAUUUGGGGAUGCAcu	UGCAUCCCCAAAUACUCCU	-2.1	-2.1	2.3	0	0	4	-39.4	49.5	-3.8	4	II	47.4	41.7	56.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2394	NM_002559	Huesken	P2RX3	5024	AAGUCGCACACCCAGCCGAuc	UCGGCUGGGUGUGCGACUU	-2.4	-0.9	-1.2	2	1	4	-44.3	46.1	-6.1	3	II	63.2	47.4	77.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2395	NM_002559	Huesken	P2RX3	5024	CACACCCAGCCGAUCUUAAug	UUAAGAUCGGCUGGGUGUG	-0.9	-2.1	0.5	0	-3	4	-39.6	53.7	-8.4	3	III	52.6	29.6	55.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2396	NM_002559	Huesken	P2RX3	5024	CCAGCCGAUCUUAAUGCCCag	GGGCAUUAAGAUCGGCUGG	-3.3	-3.3	-1	-1	1	4	-40.9	45.6	5.8	0	II	57.9	51.5	59.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2397	NM_002559	Huesken	P2RX3	5024	UGCGCGCCAGUUUGGCAAAau	UUUGCCAAACUGGCGCGCA	-0.9	-2.1	-4.5	-1	-2	7	-41.3	46.4	-0.7	1	II	57.9	37	37.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2398	NM_002559	Huesken	P2RX3	5024	UGGCAAAAUCCUGCCCCGCaa	GCGGGGCAGGAUUUUGCCA	-3.4	-2.1	-5.5	1	3	7	-43.7	44.3	10.8	3	Ib	63.2	60.8	67.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2399	NM_002559	Huesken	P2RX3	5024	GCAAAAUCCUGCCCCGCAAac	UUGCGGGGCAGGAUUUUGC	-0.9	-3.4	-3	2	-2	7	-41.3	42.6	-1	2	II	57.9	27.7	33.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2400	NM_002559	Huesken	P2RX3	5024	GACCACGUCCCCUACCCGCaa	GCGGGUAGGGGACGUGGUC	-3.4	-2.4	-1.1	2	2	5	-47.1	38.5	5.4	1	II	73.7	45.8	37.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2401	NM_002559	Huesken	P2RX3	5024	ACGUCCCCUACCCGCAAGAug	UCUUGCGGGUAGGGGACGU	-2.4	-2.2	-1.4	0	-1	5	-44.6	43.4	-6.1	2	II	63.2	36.9	75.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2402	NM_002559	Huesken	P2RX3	5024	CCGCAAGAUGGGGCAGAAAgg	UUUCUGCCCCAUCUUGCGG	-0.9	-3.3	-2.2	0	-5	5	-41.5	24.2	-3.1	0	III	57.9	20.4	35.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2403	NM_002559	Huesken	P2RX3	5024	GGUGGAAGCGGCAGGUCUUca	AAGACCUGCCGCUUCCACC	-0.9	-3.3	1.7	0	-1	5	-43.9	29	-8.9	1	III	63.2	28.3	39.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2404	NM_002559	Huesken	P2RX3	5024	UCUUCAUGUCCCUGGCUGUca	ACAGCCAGGGACAUGAAGA	-2.2	-2.4	0.8	0	1	3	-41.6	64.1	-8.7	7	II	52.6	51.9	78.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2405	NM_002559	Huesken	P2RX3	5024	UUCAUGUCCCUGGCUGUCAgg	UGACAGCCAGGGACAUGAA	-2.1	-0.9	0.8	2	0	3	-41.6	66	-3.8	8	II	52.6	63.1	90.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2406	NM_002559	Huesken	P2RX3	5024	CAUGUCCCUGGCUGUCAGGuu	CCUGACAGCCAGGGACAUG	-3.3	-2.1	-4.7	-2	1	3	-43.7	50	-4.4	1	II	63.2	44	33.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2407	NM_002559	Huesken	P2RX3	5024	UGGCUGUCAGGUUGGGAAGga	CUUCCCAACCUGACAGCCA	-2.1	-2.1	2.4	1	1	3	-42.3	59.7	3	4	II	57.9	54.1	66.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2408	NM_002559	Huesken	P2RX3	5024	UUCUUGAUGAAAAUAGUGAag	UCACUAUUUUCAUCAAGAA	-2.4	-0.9	1.1	1	1	1	-30.3	89.4	-1.7	9	II	26.3	68.9	79.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2409	NM_002559	Huesken	P2RX3	5024	UAGUGAAGUUCUCAGCUUCca	GAAGCUGAGAACUUCACUA	-2.4	-1.3	-2.3	0	2	2	-36.1	73.5	10.5	6	Ia	42.1	68.1	88.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2410	NM_002559	Huesken	P2RX3	5024	CCAUCAUGAUGGGCGUUUCca	GAAACGCCCAUCAUGAUGG	-2.4	-3.3	-2.4	0	-1	5	-38.6	57.2	5.4	3	II	52.6	41	48.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2411	NM_002559	Huesken	P2RX3	5024	AGCCCUGGAUCUCACAGGUcc	ACCUGUGAGAUCCAGGGCU	-2.2	-2.1	-4.4	2	1	4	-44	49.1	-0.9	1	II	57.9	42.5	50.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2412	NM_002559	Huesken	P2RX3	5024	ACAGGUCCGGAGCACAGAGcu	CUCUGUGCUCCGGACCUGU	-2.1	-2.2	-1.4	2	3	4	-44.2	38.8	4.7	1	II	63.2	47.8	41.9	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2413	NM_002559	Huesken	P2RX3	5024	GUCCGGAGCACAGAGCUGUag	ACAGCUCUGUGCUCCGGAC	-2.2	-2.2	-1.8	2	-1	4	-44.3	33.2	-6.3	2	III	63.2	40.7	59.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2414	NM_002559	Huesken	P2RX3	5024	CACAGAGCUGUAGUUCACGca	CGUGAACUACAGCUCUGUG	-2.4	-2.1	-0.5	-1	1	2	-38.4	49.1	0.3	3	II	52.6	52.5	42	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2415	NM_002559	Huesken	P2RX3	5024	UGUAGUUCACGCAGCGGCCag	GGCCGCUGCGUGAACUACA	-3.3	-2.1	-0.3	0	4	6	-43.3	56.8	2.5	5	Ia	63.2	65.7	72.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2416	NM_002559	Huesken	P2RX3	5024	ACGCAGCGGCCAGUGAGGAuc	UCCUCACUGGCCGCUGCGU	-2.4	-2.2	-0.3	3	1	6	-46.7	21	-1.1	2	II	68.4	32.4	16.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2417	NM_002559	Huesken	P2RX3	5024	CCUUGCAUCUGAUUUUCAGua	CUGAAAAUCAGAUGCAAGG	-2.1	-3.3	-1.8	0	1	2	-34.4	73.9	0.3	2	II	42.1	43.1	85.5	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2418	NM_002559	Huesken	P2RX3	5024	AUCUGAUUUUCAGUAACAAuc	UUGUUACUGAAAAUCAGAU	-0.9	-1.1	-2.3	2	1	1	-30.1	73.2	-3.8	4	II	26.3	47.9	54.1	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2419	NM_002559	Huesken	P2RX3	5024	UCUGAUUUUCAGUAACAAUca	AUUGUUACUGAAAAUCAGA	-1.1	-2.4	-2.3	1	0	1	-30.1	84.3	1	5	II	26.3	60.2	74.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2420	NM_002559	Huesken	P2RX3	5024	UGAUGAUGACAAAGACCGAgg	UCGGUCUUUGUCAUCAUCA	-2.4	-2.1	0.9	0	1	3	-36.6	52.8	-4	6	II	42.1	50.9	72.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2421	NM_002559	Huesken	P2RX3	5024	CCGAGGUGCCCUGAGGUGGcg	CCACCUCAGGGCACCUCGG	-3.3	-3.3	-0.7	1	-1	4	-47.4	33	-1.3	2	II	73.7	41.9	70.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2422	NM_002559	Huesken	P2RX3	5024	AGGUGCCCUGAGGUGGCGUca	ACGCCACCUCAGGGCACCU	-2.2	-2.1	-4.2	1	2	4	-47.3	40.5	0.7	1	II	68.4	39.8	8.6	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2423	NM_002559	Huesken	P2RX3	5024	GGUGGCGUCACGUAAUCAGac	CUGAUUACGUGACGCCACC	-2.1	-3.3	-1.3	1	1	4	-40.1	48.4	-2.4	1	II	57.9	39.1	50	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2424	NM_002559	Huesken	P2RX3	5024	UCCAUGACUCUGUUGGCGUag	ACGCCAACAGAGUCAUGGA	-2.2	-2.4	-0.6	0	2	4	-40.8	64.2	-1.6	6	II	52.6	59.1	89.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2425	NM_002559	Huesken	P2RX3	5024	UUGGCGUAGAGUCCGGAGCcc	GCUCCGGACUCUACGCCAA	-3.4	-0.9	-1	2	3	4	-43.7	63.8	12.8	4	II	63.2	70.9	87.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2426	NM_002559	Huesken	P2RX3	5024	GAGCCCUUCACCUUGGUUAcc	UAACCAAGGUGAAGGGCUC	-1.3	-2.4	-1	3	-2	4	-40.3	67.7	-6.1	3	III	52.6	40.5	16.2	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2427	NM_002559	Huesken	P2RX3	5024	AAAACCCACCCUACAAAGUag	ACUUUGUAGGGUGGGUUUU	-2.2	-0.9	0	2	2	3	-36.2	67.4	-5.9	5	II	42.1	55.4	89.4	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2428	NM_002559	Huesken	P2RX3	5024	GAUGAUCAGAAGCUGAACUac	AGUUCAGCUUCUGAUCAUC	-2.1	-2.4	-1.2	1	1	2	-36.3	67.9	5.8	3	II	42.1	48.1	72.3	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2429	NM_002559	Huesken	P2RX3	5024	AUCAGAAGCUGAACUACUCgg	GAGUAGUUCAGCUUCUGAU	-2.4	-1.1	-1.2	2	3	2	-36.3	63.8	4.8	4	Ia	42.1	62.3	91.8	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2430	NM_002559	Huesken	P2RX3	5024	GAAGCUGAACUACUCGGUUga	AACCGAGUAGUUCAGCUUC	-0.9	-2.4	-0.9	0	1	3	-37.4	53.6	0.8	3	III	47.4	43	62	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2431	NM_002559	Huesken	P2RX3	5024	GAUGAUCCCGAUGGUCCAGcu	CUGGACCAUCGGGAUCAUC	-2.1	-2.4	-0.7	0	2	4	-41.5	47.4	8	2	II	57.9	38.3	60.7	Luciferase reporter assay	HeLa	50nM	48h	"Design of a genome-wide siRNA library using an artificial
neural network"	16025102	2005	Nature biotechnology	2005/8/1
MC2432	AH001498	Harborth	Lamin A	33782	GAGCUCCUGCAGGUCCUCCuu	GGAGGACCUGCAGGAGCUC	-3.3	-2.4	-1	2	2	2	-46.5	48	12	1	II	68.4	46	83	Luciferase reporter assay	HeLa	100nM	24h	Sequence, chemical, and structural variation of small interfering RNAs and short hairpin RNAs and the effect on mammalian gene silencing.	12804036	2003	Antisense & Nucleic Acid Drug Development	2003/4/1
MC2433	AH001498	Harborth	Lamin A	33782	GAGCUCCUGCAGGUCCUCCuu	GGAGGACCUGCAGGAGCUC	-3.3	-2.4	-1	2	2	2	-46.5	48	12	1	II	68.4	46	83	Luciferase reporter assay	HeLa;SW3T3	100nM	24h	Sequence, chemical, and structural variation of small interfering RNAs and short hairpin RNAs and the effect on mammalian gene silencing.	12804036	2003	Antisense & Nucleic Acid Drug Development	2003/4/1
MC2434	AH001498	Harborth	Lamin A	33782	GAGCUCCUGCAGGUCCUCCuu	GGAGGACCUGCAGGAGCUC	-3.3	-2.4	-1	2	2	2	-46.5	48	12	1	II	68.4	46	83	Luciferase reporter assay	HeLa;SW3T3	100nM	24h	Sequence, chemical, and structural variation of small interfering RNAs and short hairpin RNAs and the effect on mammalian gene silencing.	12804036	2003	Antisense & Nucleic Acid Drug Development	2003/4/1
MC2435	AH001498	Harborth	Lamin A	33782	GAGCUCCUGCAGGUCCUCCuu	GGAGGACCUGCAGGAGCUC	-3.3	-2.4	-1	2	2	2	-46.5	48	12	1	II	68.4	46	83	Luciferase reporter assay	HeLa;SW3T3	100nM	24h	Sequence, chemical, and structural variation of small interfering RNAs and short hairpin RNAs and the effect on mammalian gene silencing.	12804036	2003	Antisense & Nucleic Acid Drug Development	2003/4/1
MC2436	AH001498	Harborth	Lamin A	33782	GAGCUCCUGCAGGUCCUCCuu	GGAGGACCUGCAGGAGCUC	-3.3	-2.4	-1	2	2	2	-46.5	48	12	1	II	68.4	46	83	Luciferase reporter assay	HeLa;SW3T3	100nM	24h	Sequence, chemical, and structural variation of small interfering RNAs and short hairpin RNAs and the effect on mammalian gene silencing.	12804036	2003	Antisense & Nucleic Acid Drug Development	2003/4/1
MC2437	AH001498	Harborth	Lamin A	33782	GAGCUCCUGCAGGUCCUCCuu	GGAGGACCUGCAGGAGCUC	-3.3	-2.4	-1	2	2	2	-46.5	48	12	1	II	68.4	46	83	Luciferase reporter assay	HeLa;SW3T3	100nM	24h	Sequence, chemical, and structural variation of small interfering RNAs and short hairpin RNAs and the effect on mammalian gene silencing.	12804036	2003	Antisense & Nucleic Acid Drug Development	2003/4/1
MC2438	AH001498	Harborth	Lamin A	33782	GAGCUCCUGCAGGUCCUCCuu	GGAGGACCUGCAGGAGCUC	-3.3	-2.4	-1	2	2	2	-46.5	48	12	1	II	68.4	46	83	Luciferase reporter assay	HeLa;SW3T3	100nM	24h	Sequence, chemical, and structural variation of small interfering RNAs and short hairpin RNAs and the effect on mammalian gene silencing.	12804036	2003	Antisense & Nucleic Acid Drug Development	2003/4/1
MC2439	AH001498	Harborth	Lamin A	33782	GAGCUCCUGCAGGUCCUCCuu	GGAGGACCUGCAGGAGCUC	-3.3	-2.4	-1	2	2	2	-46.5	48	12	1	II	68.4	46	83	Luciferase reporter assay	HeLa;SW3T3	100nM	24h	Sequence, chemical, and structural variation of small interfering RNAs and short hairpin RNAs and the effect on mammalian gene silencing.	12804036	2003	Antisense & Nucleic Acid Drug Development	2003/4/1
MC2440	AH001498	Harborth	Lamin A	33782	GAGCUCCUGCAGGUCCUCCuu	GGAGGACCUGCAGGAGCUC	-3.3	-2.4	-1	2	2	2	-46.5	48	12	1	II	68.4	46	83	Luciferase reporter assay	HeLa;SW3T3	100nM	24h	Sequence, chemical, and structural variation of small interfering RNAs and short hairpin RNAs and the effect on mammalian gene silencing.	12804036	2003	Antisense & Nucleic Acid Drug Development	2003/4/1
MC2441	AH001498	Harborth	Lamin A	33782	GAGCUCCUGCAGGUCCUCCuu	GGAGGACCUGCAGGAGCUC	-3.3	-2.4	-1	2	2	2	-46.5	48	12	1	II	68.4	46	83	Luciferase reporter assay	HeLa;SW3T3	100nM	24h	Sequence, chemical, and structural variation of small interfering RNAs and short hairpin RNAs and the effect on mammalian gene silencing.	12804036	2003	Antisense & Nucleic Acid Drug Development	2003/4/1
MC2442	AH001498	Harborth	Lamin A	33782	GAGCUCCUGCAGGUCCUCCuu	GGAGGACCUGCAGGAGCUC	-3.3	-2.4	-1	2	2	2	-46.5	48	12	1	II	68.4	46	83	Luciferase reporter assay	HeLa;SW3T3	100nM	24h	Sequence, chemical, and structural variation of small interfering RNAs and short hairpin RNAs and the effect on mammalian gene silencing.	12804036	2003	Antisense & Nucleic Acid Drug Development	2003/4/1
MC2443	AH001498	Harborth	Lamin A	33782	GAGCUCCUGCAGGUCCUCCuu	GGAGGACCUGCAGGAGCUC	-3.3	-2.4	-1	2	2	2	-46.5	48	12	1	II	68.4	46	83	Luciferase reporter assay	HeLa;SW3T3	100nM	24h	Sequence, chemical, and structural variation of small interfering RNAs and short hairpin RNAs and the effect on mammalian gene silencing.	12804036	2003	Antisense & Nucleic Acid Drug Development	2003/4/1
MC2444	AH001498	Harborth	Lamin A	33782	GAGCUCCUGCAGGUCCUCCuu	GGAGGACCUGCAGGAGCUC	-3.3	-2.4	-1	2	2	2	-46.5	48	12	1	II	68.4	46	83	Luciferase reporter assay	HeLa;SW3T3	100nM	24h	Sequence, chemical, and structural variation of small interfering RNAs and short hairpin RNAs and the effect on mammalian gene silencing.	12804036	2003	Antisense & Nucleic Acid Drug Development	2003/4/1
MC2445	AH001498	Harborth	Lamin A	33782	GAGCUCCUGCAGGUCCUCCuu	GGAGGACCUGCAGGAGCUC	-3.3	-2.4	-1	2	2	2	-46.5	48	12	1	II	68.4	46	83	Luciferase reporter assay	HeLa;SW3T3	100nM	24h	Sequence, chemical, and structural variation of small interfering RNAs and short hairpin RNAs and the effect on mammalian gene silencing.	12804036	2003	Antisense & Nucleic Acid Drug Development	2003/4/1
MC2446	AH001498	Harborth	Lamin A	33782	GAGCUCCUGCAGGUCCUCCuu	GGAGGACCUGCAGGAGCUC	-3.3	-2.4	-1	2	2	2	-46.5	48	12	1	II	68.4	46	83	Luciferase reporter assay	HeLa;SW3T3	100nM	24h	Sequence, chemical, and structural variation of small interfering RNAs and short hairpin RNAs and the effect on mammalian gene silencing.	12804036	2003	Antisense & Nucleic Acid Drug Development	2003/4/1
MC2447	AH001498	Harborth	Lamin A	33782	GAGCUCCUGCAGGUCCUCCuu	GGAGGACCUGCAGGAGCUC	-3.3	-2.4	-1	2	2	2	-46.5	48	12	1	II	68.4	46	83	Luciferase reporter assay	HeLa;SW3T3	100nM	24h	Sequence, chemical, and structural variation of small interfering RNAs and short hairpin RNAs and the effect on mammalian gene silencing.	12804036	2003	Antisense & Nucleic Acid Drug Development	2003/4/1
MC2448	AH001498	Harborth	Lamin A	33782	GAGCUCCUGCAGGUCCUCCuu	GGAGGACCUGCAGGAGCUC	-3.3	-2.4	-1	2	2	2	-46.5	48	12	1	II	68.4	46	83	Luciferase reporter assay	HeLa;SW3T3	100nM	24h	Sequence, chemical, and structural variation of small interfering RNAs and short hairpin RNAs and the effect on mammalian gene silencing.	12804036	2003	Antisense & Nucleic Acid Drug Development	2003/4/1
MC2449	AH001498	Harborth	Lamin A	33782	GAGCUCCUGCAGGUCCUCCuu	GGAGGACCUGCAGGAGCUC	-3.3	-2.4	-1	2	2	2	-46.5	48	12	1	II	68.4	46	83	Luciferase reporter assay	HeLa;SW3T3	100nM	24h	Sequence, chemical, and structural variation of small interfering RNAs and short hairpin RNAs and the effect on mammalian gene silencing.	12804036	2003	Antisense & Nucleic Acid Drug Development	2003/4/1
MC2450	AH001498	Harborth	Lamin A	33782	GAGCUCCUGCAGGUCCUCCuu	GGAGGACCUGCAGGAGCUC	-3.3	-2.4	-1	2	2	2	-46.5	48	12	1	II	68.4	46	83	Luciferase reporter assay	HeLa;SW3T3	100nM	24h	Sequence, chemical, and structural variation of small interfering RNAs and short hairpin RNAs and the effect on mammalian gene silencing.	12804036	2003	Antisense & Nucleic Acid Drug Development	2003/4/1
MC2451	AH001498	Harborth	Lamin A	33782	GAGCUCCUGCAGGUCCUCCuu	GGAGGACCUGCAGGAGCUC	-3.3	-2.4	-1	2	2	2	-46.5	48	12	1	II	68.4	46	83	Luciferase reporter assay	HeLa;SW3T3	100nM	24h	Sequence, chemical, and structural variation of small interfering RNAs and short hairpin RNAs and the effect on mammalian gene silencing.	12804036	2003	Antisense & Nucleic Acid Drug Development	2003/4/1
MC2452	AH001498	Harborth	Lamin A	33782	GAGCUCCUGCAGGUCCUCCuu	GGAGGACCUGCAGGAGCUC	-3.3	-2.4	-1	2	2	2	-46.5	48	12	1	II	68.4	46	83	Luciferase reporter assay	HeLa;SW3T3	100nM	24h	Sequence, chemical, and structural variation of small interfering RNAs and short hairpin RNAs and the effect on mammalian gene silencing.	12804036	2003	Antisense & Nucleic Acid Drug Development	2003/4/1
MC2453	AH001498	Harborth	Lamin A	33782	GAGCUCCUGCAGGUCCUCCuu	GGAGGACCUGCAGGAGCUC	-3.3	-2.4	-1	2	2	2	-46.5	48	12	1	II	68.4	46	83	Luciferase reporter assay	HeLa;SW3T3	100nM	24h	Sequence, chemical, and structural variation of small interfering RNAs and short hairpin RNAs and the effect on mammalian gene silencing.	12804036	2003	Antisense & Nucleic Acid Drug Development	2003/4/1
MC2454	AH001498	Harborth	Lamin A	33782	GAGCUCCUGCAGGUCCUCCuu	GGAGGACCUGCAGGAGCUC	-3.3	-2.4	-1	2	2	2	-46.5	48	12	1	II	68.4	46	83	Luciferase reporter assay	HeLa;SW3T3	100nM	24h	Sequence, chemical, and structural variation of small interfering RNAs and short hairpin RNAs and the effect on mammalian gene silencing.	12804036	2003	Antisense & Nucleic Acid Drug Development	2003/4/1
MC2455	AH001498	Harborth	Lamin A	33782	GAGCUCCUGCAGGUCCUCCuu	GGAGGACCUGCAGGAGCUC	-3.3	-2.4	-1	2	2	2	-46.5	48	12	1	II	68.4	46	83	Luciferase reporter assay	HeLa;SW3T3	100nM	24h	Sequence, chemical, and structural variation of small interfering RNAs and short hairpin RNAs and the effect on mammalian gene silencing.	12804036	2003	Antisense & Nucleic Acid Drug Development	2003/4/1
MC2456	AH001498	Harborth	Lamin A	33782	GAGCUCCUGCAGGUCCUCCuu	GGAGGACCUGCAGGAGCUC	-3.3	-2.4	-1	2	2	2	-46.5	48	12	1	II	68.4	46	83	Luciferase reporter assay	HeLa;SW3T3	100nM	24h	Sequence, chemical, and structural variation of small interfering RNAs and short hairpin RNAs and the effect on mammalian gene silencing.	12804036	2003	Antisense & Nucleic Acid Drug Development	2003/4/1
MC2457	AH001498	Harborth	Lamin A	33782	GAGCUCCUGCAGGUCCUCCuu	GGAGGACCUGCAGGAGCUC	-3.3	-2.4	-1	2	2	2	-46.5	48	12	1	II	68.4	46	83	Luciferase reporter assay	HeLa;SW3T3	100nM	24h	Sequence, chemical, and structural variation of small interfering RNAs and short hairpin RNAs and the effect on mammalian gene silencing.	12804036	2003	Antisense & Nucleic Acid Drug Development	2003/4/1
MC2458	AH001498	Harborth	Lamin A	33782	GAGCUCCUGCAGGUCCUCCuu	GGAGGACCUGCAGGAGCUC	-3.3	-2.4	-1	2	2	2	-46.5	48	12	1	II	68.4	46	83	Luciferase reporter assay	HeLa;SW3T3	100nM	24h	Sequence, chemical, and structural variation of small interfering RNAs and short hairpin RNAs and the effect on mammalian gene silencing.	12804036	2003	Antisense & Nucleic Acid Drug Development	2003/4/1
MC2459	AH001498	Harborth	Lamin A	33782	GAGCUCCUGCAGGUCCUCCuu	GGAGGACCUGCAGGAGCUC	-3.3	-2.4	-1	2	2	2	-46.5	48	12	1	II	68.4	46	83	Luciferase reporter assay	HeLa;SW3T3	100nM	24h	Sequence, chemical, and structural variation of small interfering RNAs and short hairpin RNAs and the effect on mammalian gene silencing.	12804036	2003	Antisense & Nucleic Acid Drug Development	2003/4/1
MC2460	AH001498	Harborth	Lamin A	33782	GAGCUCCUGCAGGUCCUCCuu	GGAGGACCUGCAGGAGCUC	-3.3	-2.4	-1	2	2	2	-46.5	48	12	1	II	68.4	46	83	Luciferase reporter assay	HeLa;SW3T3	100nM	24h	Sequence, chemical, and structural variation of small interfering RNAs and short hairpin RNAs and the effect on mammalian gene silencing.	12804036	2003	Antisense & Nucleic Acid Drug Development	2003/4/1
MC2461	AH001498	Harborth	Lamin A	33782	GAGCUCCUGCAGGUCCUCCuu	GGAGGACCUGCAGGAGCUC	-3.3	-2.4	-1	2	2	2	-46.5	48	12	1	II	68.4	46	83	Luciferase reporter assay	HeLa;SW3T3	100nM	24h	Sequence, chemical, and structural variation of small interfering RNAs and short hairpin RNAs and the effect on mammalian gene silencing.	12804036	2003	Antisense & Nucleic Acid Drug Development	2003/4/1
MC2462	AH001498	Harborth	Lamin A	33782	GAGCUCCUGCAGGUCCUCCuu	GGAGGACCUGCAGGAGCUC	-3.3	-2.4	-1	2	2	2	-46.5	48	12	1	II	68.4	46	83	Luciferase reporter assay	HeLa;SW3T3	100nM	24h	Sequence, chemical, and structural variation of small interfering RNAs and short hairpin RNAs and the effect on mammalian gene silencing.	12804036	2003	Antisense & Nucleic Acid Drug Development	2003/4/1
MC2463	AH001498	Harborth	Lamin A	33782	GAGCUCCUGCAGGUCCUCCuu	GGAGGACCUGCAGGAGCUC	-3.3	-2.4	-1	2	2	2	-46.5	48	12	1	II	68.4	46	83	Luciferase reporter assay	HeLa;SW3T3	100nM	24h	Sequence, chemical, and structural variation of small interfering RNAs and short hairpin RNAs and the effect on mammalian gene silencing.	12804036	2003	Antisense & Nucleic Acid Drug Development	2003/4/1
MC2464	AH001498	Harborth	Lamin A	33782	GAGCUCCUGCAGGUCCUCCuu	GGAGGACCUGCAGGAGCUC	-3.3	-2.4	-1	2	2	2	-46.5	48	12	1	II	68.4	46	83	Luciferase reporter assay	HeLa;SW3T3	100nM	24h	Sequence, chemical, and structural variation of small interfering RNAs and short hairpin RNAs and the effect on mammalian gene silencing.	12804036	2003	Antisense & Nucleic Acid Drug Development	2003/4/1
MC2465	AH001498	Harborth	Lamin A	33782	GAGCUCCUGCAGGUCCUCCuu	GGAGGACCUGCAGGAGCUC	-3.3	-2.4	-1	2	2	2	-46.5	48	12	1	II	68.4	46	83	Luciferase reporter assay	HeLa;SW3T3	100nM	24h	Sequence, chemical, and structural variation of small interfering RNAs and short hairpin RNAs and the effect on mammalian gene silencing.	12804036	2003	Antisense & Nucleic Acid Drug Development	2003/4/1
MC2466	AH001498	Harborth	Lamin A	33782	GAGCUCCUGCAGGUCCUCCuu	GGAGGACCUGCAGGAGCUC	-3.3	-2.4	-1	2	2	2	-46.5	48	12	1	II	68.4	46	83	Luciferase reporter assay	HeLa;SW3T3	100nM	24h	Sequence, chemical, and structural variation of small interfering RNAs and short hairpin RNAs and the effect on mammalian gene silencing.	12804036	2003	Antisense & Nucleic Acid Drug Development	2003/4/1
MC2467	AH001498	Harborth	Lamin A	33782	GAGCUCCUGCAGGUCCUCCuu	GGAGGACCUGCAGGAGCUC	-3.3	-2.4	-1	2	2	2	-46.5	48	12	1	II	68.4	46	83	Luciferase reporter assay	HeLa;SW3T3	100nM	24h	Sequence, chemical, and structural variation of small interfering RNAs and short hairpin RNAs and the effect on mammalian gene silencing.	12804036	2003	Antisense & Nucleic Acid Drug Development	2003/4/1
MC2468	AH001498	Harborth	Lamin A	33782	GAGCUCCUGCAGGUCCUCCuu	GGAGGACCUGCAGGAGCUC	-3.3	-2.4	-1	2	2	2	-46.5	48	12	1	II	68.4	46	83	Luciferase reporter assay	HeLa;SW3T3	100nM	24h	Sequence, chemical, and structural variation of small interfering RNAs and short hairpin RNAs and the effect on mammalian gene silencing.	12804036	2003	Antisense & Nucleic Acid Drug Development	2003/4/1
MC2469	AH001498	Harborth	Lamin A	33782	GAGCUCCUGCAGGUCCUCCuu	GGAGGACCUGCAGGAGCUC	-3.3	-2.4	-1	2	2	2	-46.5	48	12	1	II	68.4	46	83	Luciferase reporter assay	HeLa;SW3T3	100nM	24h	Sequence, chemical, and structural variation of small interfering RNAs and short hairpin RNAs and the effect on mammalian gene silencing.	12804036	2003	Antisense & Nucleic Acid Drug Development	2003/4/1
MC2470	AH001498	Harborth	Lamin A	33782	GAGCUCCUGCAGGUCCUCCuu	GGAGGACCUGCAGGAGCUC	-3.3	-2.4	-1	2	2	2	-46.5	48	12	1	II	68.4	46	83	Luciferase reporter assay	HeLa;SW3T3	100nM	24h	Sequence, chemical, and structural variation of small interfering RNAs and short hairpin RNAs and the effect on mammalian gene silencing.	12804036	2003	Antisense & Nucleic Acid Drug Development	2003/4/1
MC2471	AH001498	Harborth	Lamin A	33782	GAGCUCCUGCAGGUCCUCCuu	GGAGGACCUGCAGGAGCUC	-3.3	-2.4	-1	2	2	2	-46.5	48	12	1	II	68.4	46	83	Luciferase reporter assay	HeLa;SW3T3	100nM	24h	Sequence, chemical, and structural variation of small interfering RNAs and short hairpin RNAs and the effect on mammalian gene silencing.	12804036	2003	Antisense & Nucleic Acid Drug Development	2003/4/1
MC2472	AH001498	Harborth	Lamin A	33782	GAGCUCCUGCAGGUCCUCCuu	GGAGGACCUGCAGGAGCUC	-3.3	-2.4	-1	2	2	2	-46.5	48	12	1	II	68.4	46	83	Luciferase reporter assay	HeLa;SW3T3	100nM	24h	Sequence, chemical, and structural variation of small interfering RNAs and short hairpin RNAs and the effect on mammalian gene silencing.	12804036	2003	Antisense & Nucleic Acid Drug Development	2003/4/1
MC2473	AH001498	Harborth	Lamin A	33782	GAGCUCCUGCAGGUCCUCCuu	GGAGGACCUGCAGGAGCUC	-3.3	-2.4	-1	2	2	2	-46.5	48	12	1	II	68.4	46	83	Luciferase reporter assay	HeLa;SW3T3	100nM	24h	Sequence, chemical, and structural variation of small interfering RNAs and short hairpin RNAs and the effect on mammalian gene silencing.	12804036	2003	Antisense & Nucleic Acid Drug Development	2003/4/1
MC2474	AH001498	Harborth	Lamin A	33782	GAGCUCCUGCAGGUCCUCCuu	GGAGGACCUGCAGGAGCUC	-3.3	-2.4	-1	2	2	2	-46.5	48	12	1	II	68.4	46	83	Luciferase reporter assay	HeLa;SW3T3	100nM	24h	Sequence, chemical, and structural variation of small interfering RNAs and short hairpin RNAs and the effect on mammalian gene silencing.	12804036	2003	Antisense & Nucleic Acid Drug Development	2003/4/1
MC2475	AH001498	Harborth	Lamin A	33782	GAGCUCCUGCAGGUCCUCCuu	GGAGGACCUGCAGGAGCUC	-3.3	-2.4	-1	2	2	2	-46.5	48	12	1	II	68.4	46	83	Luciferase reporter assay	HeLa;SW3T3	100nM	24h	Sequence, chemical, and structural variation of small interfering RNAs and short hairpin RNAs and the effect on mammalian gene silencing.	12804036	2003	Antisense & Nucleic Acid Drug Development	2003/4/1
MC2476	U47298	Ui-Tei	FireflyLuc	116160065	UCUUUAUGUUUUUGGCGUCuu	GACGCCAAAAACAUAAAGA	-2.4	-2.4		0	3	4	-32.4	80.6	10.4	7	Ia	36.8	62.9	85.8	Luciferase reporter assay	CHO-K1;HeLa;E14TG2a ;S2	50nM	24h	Guidelines for the selection of highly effective siRNA sequences for mammalian and chick RNA interference	14769950	2004	Nucleic Acids Research	2004/3/1
MC2477	U47298	Ui-Tei	FireflyLuc	116160065	UUCUUUAUGUUUUUGGCGUcu	ACGCCAAAAACAUAAAGAA	-2.2	-0.9		1	3	4	-30.9	97.4	1.4	7	II	31.6	70.3	94.9	Luciferase reporter assay	CHO-K1;HeLa;E14TG2a ;S2	50nM	24h	Guidelines for the selection of highly effective siRNA sequences for mammalian and chick RNA interference	14769950	2004	Nucleic Acids Research	2004/3/1
MC2478	U47298	Ui-Tei	FireflyLuc	116160065	GGGCCUUUCUUUAUGUUUUug	AAAACAUAAAGAAAGGCCC	-0.9	-3.3		3	-2	5	-32.9	77.2	-1.2	2	III	36.8	41.3	11.1	Luciferase reporter assay	CHO-K1;HeLa;E14TG2a ;S2	50nM	24h	Guidelines for the selection of highly effective siRNA sequences for mammalian and chick RNA interference	14769950	2004	Nucleic Acids Research	2004/3/1
MC2479	U47298	Ui-Tei	FireflyLuc	116160065	CCGGGCCUUUCUUUAUGUUuu	AACAUAAAGAAAGGCCCGG	-0.9	-3.3		-1	-2	7	-36.8	55.4	-3	0	III	47.4	29.8	7.6	Luciferase reporter assay	CHO-K1;HeLa;E14TG2a ;S2	50nM	24h	Guidelines for the selection of highly effective siRNA sequences for mammalian and chick RNA interference	14769950	2004	Nucleic Acids Research	2004/3/1
MC2480	U47298	Ui-Tei	FireflyLuc	116160065	GGCGCCGGGCCUUUCUUUAug	UAAAGAAAGGCCCGGCGCC	-1.3	-3.3	-2.2	1	-3	11	-43	46.4	-0.8	0	III	63.2	23.8	5.9	Luciferase reporter assay	CHO-K1;HeLa;E14TG2a ;S2	50nM	24h	Guidelines for the selection of highly effective siRNA sequences for mammalian and chick RNA interference	14769950	2004	Nucleic Acids Research	2004/3/1
MC2481	U47298	Ui-Tei	FireflyLuc	116160065	UAGAAUGGCGCCGGGCCUUuc	AAGGCCCGGCGCCAUUCUA	-0.9	-1.3	-3.9	0	1	11	-44.4	41.4	-6	5	II	63.2	55.6	23	Luciferase reporter assay	CHO-K1;HeLa;E14TG2a ;S2	50nM	24h	Guidelines for the selection of highly effective siRNA sequences for mammalian and chick RNA interference	14769950	2004	Nucleic Acids Research	2004/3/1
MC2482	U47298	Ui-Tei	FireflyLuc	116160065	AGCGGAUAGAAUGGCGCCGgg	CGGCGCCAUUCUAUCCGCU	-2.4	-2.1	-1.9	2	3	7	-42.8	41.2	5.3	2	II	63.2	52.3	53.8	Luciferase reporter assay	CHO-K1;HeLa;E14TG2a ;S2	50nM	24h	Guidelines for the selection of highly effective siRNA sequences for mammalian and chick RNA interference	14769950	2004	Nucleic Acids Research	2004/3/1
MC2483	U47298	Ui-Tei	FireflyLuc	116160065	UCUUCCAGCGGAUAGAAUGgc	CAUUCUAUCCGCUGGAAGA	-2.1	-2.4	-1.7	1	2	4	-37.8	73.2	0	5	Ib	47.4	64.9	93.2	Luciferase reporter assay	CHO-K1;HeLa;E14TG2a ;S2	50nM	24h	Guidelines for the selection of highly effective siRNA sequences for mammalian and chick RNA interference	14769950	2004	Nucleic Acids Research	2004/3/1
MC2484	U47298	Ui-Tei	FireflyLuc	116160065	GUUCCAUCUUCCAGCGGAUag	AUCCGCUGGAAGAUGGAAC	-1.1	-2.2	-2.2	1	0	4	-39.9	46.4	-11.3	2	II	52.6	32.1	23.4	Luciferase reporter assay	CHO-K1;HeLa;E14TG2a ;S2	50nM	24h	Guidelines for the selection of highly effective siRNA sequences for mammalian and chick RNA interference	14769950	2004	Nucleic Acids Research	2004/3/1
MC2485	U47298	Ui-Tei	FireflyLuc	116160065	CCAGCGGUUCCAUCUUCCAgc	UGGAAGAUGGAACCGCUGG	-2.1	-3.3	0.3	-1	-2	4	-41.8	42.4	-8.1	1	III	57.9	36.8	16.6	Luciferase reporter assay	CHO-K1;HeLa;E14TG2a ;S2	50nM	24h	Guidelines for the selection of highly effective siRNA sequences for mammalian and chick RNA interference	14769950	2004	Nucleic Acids Research	2004/3/1
MC2486	U47298	Ui-Tei	FireflyLuc	116160065	UGCUCUCCAGCGGUUCCAUcu	AUGGAACCGCUGGAGAGCA	-1.1	-2.1	-2.6	0	1	4	-43.1	57.6	-4	2	II	57.9	43.6	35.4	Luciferase reporter assay	CHO-K1;HeLa;E14TG2a ;S2	50nM	24h	Guidelines for the selection of highly effective siRNA sequences for mammalian and chick RNA interference	14769950	2004	Nucleic Acids Research	2004/3/1
MC2487	U47298	Ui-Tei	FireflyLuc	116160065	UUUCAUAGCUUCUGCCAACcg	GUUGGCAGAAGCUAUGAAA	-2.2	-0.9	-2.7	1	3	3	-35.7	71.7	7.8	6	Ia	42.1	69.1	93.1	Luciferase reporter assay	CHO-K1;HeLa;E14TG2a ;S2	50nM	24h	Guidelines for the selection of highly effective siRNA sequences for mammalian and chick RNA interference	14769950	2004	Nucleic Acids Research	2004/3/1
MC2488	U47298	Ui-Tei	FireflyLuc	116160065	CGCGCCCAACACCGGCAUAaa	UAUGCCGGUGUUGGGCGCG	-1.3	-2.4	-4.1	-2	-5	7	-44.6	28.3	-3.4	-2	III	68.4	17.1	19.7	Luciferase reporter assay	CHO-K1;HeLa;E14TG2a ;S2	50nM	24h	Guidelines for the selection of highly effective siRNA sequences for mammalian and chick RNA interference	14769950	2004	Nucleic Acids Research	2004/3/1
MC2489	U47298	Ui-Tei	FireflyLuc	116160065	UAAAUAACGCGCCCAACACcg	GUGUUGGGCGCGUUAUUUA	-2.2	-1.3	-2.2	1	4	7	-36.3	69.2	7.5	7	Ia	47.4	69.4	91.9	Luciferase reporter assay	CHO-K1;HeLa;E14TG2a ;S2	50nM	24h	Guidelines for the selection of highly effective siRNA sequences for mammalian and chick RNA interference	14769950	2004	Nucleic Acids Research	2004/3/1
MC2490	U47298	Ui-Tei	FireflyLuc	116160065	CGCGGGCGCAACUGCAACUcc	AGUUGCAGUUGCGCCCGCG	-2.1	-2.4	-1.5	-1	-3	9	-44.1	32.4	-6	-1	III	68.4	33.9	37.3	Luciferase reporter assay	CHO-K1;HeLa;E14TG2a ;S2	50nM	24h	Guidelines for the selection of highly effective siRNA sequences for mammalian and chick RNA interference	14769950	2004	Nucleic Acids Research	2004/3/1
MC2491	U47298	Ui-Tei	FireflyLuc	116160065	UUAUAAAUGUCGUUCGCGGgc	CCGCGAACGACAUUUAUAA	-3.3	-0.9	0.7	1	6	5	-33.6	78.2	2.7	8	Ia	42.1	73.9	94.9	Luciferase reporter assay	CHO-K1;HeLa;E14TG2a ;S2	50nM	24h	Guidelines for the selection of highly effective siRNA sequences for mammalian and chick RNA interference	14769950	2004	Nucleic Acids Research	2004/3/1
MC2492	U47298	Ui-Tei	FireflyLuc	116160065	GGGAGCUUUUUUUGCACGUuc	ACGUGCAAAAAAAGCUCCC	-2.2	-3.3	-0.2	0	-1	3	-36.4	58.9	-1	2	III	47.4	38	30	Luciferase reporter assay	CHO-K1;HeLa;E14TG2a ;S2	50nM	24h	Guidelines for the selection of highly effective siRNA sequences for mammalian and chick RNA interference	14769950	2004	Nucleic Acids Research	2004/3/1
MC2493	U47298	Ui-Tei	FireflyLuc	116160065	UAAUUUUUUGGAUGAUUGGga	CCAAUCAUCCAAAAAAUUA	-3.3	-1.3	3.8	0	4	2	-28.6	98.5	0	9	Ia	26.3	77.9	97.5	Luciferase reporter assay	CHO-K1;HeLa;E14TG2a ;S2	50nM	24h	Guidelines for the selection of highly effective siRNA sequences for mammalian and chick RNA interference	14769950	2004	Nucleic Acids Research	2004/3/1
MC2494	U47298	Ui-Tei	FireflyLuc	116160065	AUUCAUUAAAACCGGGAGGua	CCUCCCGGUUUUAAUGAAU	-3.3	-1.1	0.3	2	4	5	-34.8	72.9	5.1	7	Ia	42.1	65.6	73.5	Luciferase reporter assay	CHO-K1;HeLa;E14TG2a ;S2	50nM	24h	Guidelines for the selection of highly effective siRNA sequences for mammalian and chick RNA interference	14769950	2004	Nucleic Acids Research	2004/3/1
MC2495	U47298	Ui-Tei	FireflyLuc	116160065	UUCUAUGAGGCAGAGCGACac	GUCGCUCUGCCUCAUAGAA	-2.2	-0.9	-0.4	1	3	3	-40.2	54.8	7.8	7	Ia	52.6	63.4	69.9	Luciferase reporter assay	CHO-K1;HeLa;E14TG2a ;S2	50nM	24h	Guidelines for the selection of highly effective siRNA sequences for mammalian and chick RNA interference	14769950	2004	Nucleic Acids Research	2004/3/1
MC2496	U47298	Ui-Tei	FireflyLuc	116160065	AAUAGGAUCUCUGGCAUGCga	GCAUGCCAGAGAUCCUAUU	-3.4	-0.9	1.5	1	4	3	-38.7	65.5	8.1	7	Ia	47.4	63.8	94.5	Luciferase reporter assay	CHO-K1;HeLa;E14TG2a ;S2	50nM	24h	Guidelines for the selection of highly effective siRNA sequences for mammalian and chick RNA interference	14769950	2004	Nucleic Acids Research	2004/3/1
MC2497	U47298	Ui-Tei	FireflyLuc	116160065	UUAAAAUCGCAGUAUCCGGaa	CCGGAUACUGCGAUUUUAA	-3.3	-0.9	0.7	2	5	4	-34.4	76.1	5	8	Ia	42.1	76.1	96.3	Luciferase reporter assay	CHO-K1;HeLa;E14TG2a ;S2	50nM	24h	Guidelines for the selection of highly effective siRNA sequences for mammalian and chick RNA interference	14769950	2004	Nucleic Acids Research	2004/3/1
MC2498	U47298	Ui-Tei	FireflyLuc	116160065	UAGUAAACAUUCCAAAACCgu	GGUUUUGGAAUGUUUACUA	-3.3	-1.3	1.4	0	3	2	-31	79	10.2	7	Ia	31.6	76.7	93.3	Luciferase reporter assay	CHO-K1;HeLa;E14TG2a ;S2	50nM	24h	Guidelines for the selection of highly effective siRNA sequences for mammalian and chick RNA interference	14769950	2004	Nucleic Acids Research	2004/3/1
MC2499	U47298	Ui-Tei	FireflyLuc	116160065	AUUAAGACGACUCGAAAUCca	GAUUUCGAGUCGUCUUAAU	-2.4	-1.1	-0.5	1	3	2	-32.5	72.9	13.2	8	Ia	36.8	66.9	98.9	Luciferase reporter assay	CHO-K1;HeLa;E14TG2a ;S2	50nM	24h	Guidelines for the selection of highly effective siRNA sequences for mammalian and chick RNA interference	14769950	2004	Nucleic Acids Research	2004/3/1
MC2500	U47298	Ui-Tei	FireflyLuc	116160065	AAUCUUGUAAUCCUGAAGGcu	CCUUCAGGAUUACAAGAUU	-3.3	-0.9	-0.5	2	5	2	-33.6	85.2	2.4	7	Ia	36.8	72	98.9	Luciferase reporter assay	CHO-K1;HeLa;E14TG2a ;S2	50nM	24h	Guidelines for the selection of highly effective siRNA sequences for mammalian and chick RNA interference	14769950	2004	Nucleic Acids Research	2004/3/1
MC2501	U47298	Ui-Tei	FireflyLuc	116160065	UAGAUAAAUCGUAUUUGUCaa	GACAAAUACGAUUUAUCUA	-2.4	-1.3	1.4	0	4	2	-29	94	10.2	7	Ia	26.3	74.8	86.5	Luciferase reporter assay	CHO-K1;HeLa;E14TG2a ;S2	50nM	24h	Guidelines for the selection of highly effective siRNA sequences for mammalian and chick RNA interference	14769950	2004	Nucleic Acids Research	2004/3/1
MC2502	U47298	Ui-Tei	FireflyLuc	116160065	AUUAGAUAAAUCGUAUUUGuc	CAAAUACGAUUUAUCUAAU	-2.1	-1.1	1.4	2	4	2	-26.4	89.6	0	8	Ia	21.1	70.7	87.8	Luciferase reporter assay	CHO-K1;HeLa;E14TG2a ;S2	50nM	24h	Guidelines for the selection of highly effective siRNA sequences for mammalian and chick RNA interference	14769950	2004	Nucleic Acids Research	2004/3/1
MC2503	U47298	Ui-Tei	FireflyLuc	116160065	CCCUCGGGUGUAAUCAGAAua	UUCUGAUUACACCCGAGGG	-0.9	-3.3	-1.1	-1	-3	4	-39.8	41.3	-6	1	III	52.6	29.8	10.7	Luciferase reporter assay	CHO-K1;HeLa;E14TG2a ;S2	50nM	24h	Guidelines for the selection of highly effective siRNA sequences for mammalian and chick RNA interference	14769950	2004	Nucleic Acids Research	2004/3/1
MC2504	U47298	Ui-Tei	FireflyLuc	116160065	CCGCGCCCGGUUUAUCAUCcc	GAUGAUAAACCGGGCGCGG	-2.4	-3.3	-2	1	-2	10	-41.6	40	8.4	-2	II	63.2	38.8	52.9	Luciferase reporter assay	CHO-K1;HeLa;E14TG2a ;S2	50nM	24h	Guidelines for the selection of highly effective siRNA sequences for mammalian and chick RNA interference	14769950	2004	Nucleic Acids Research	2004/3/1
MC2505	U47298	Ui-Tei	FireflyLuc	116160065	AACUUUACCGACCGCGCCCgg	GGGCGCGGUCGGUAAAGUU	-3.3	-0.9	-1.3	1	4	8	-42.3	60.8	9.8	4	Ia	63.2	64.9	93.6	Luciferase reporter assay	CHO-K1;HeLa;E14TG2a ;S2	50nM	24h	Guidelines for the selection of highly effective siRNA sequences for mammalian and chick RNA interference	14769950	2004	Nucleic Acids Research	2004/3/1
MC2506	U47298	Ui-Tei	FireflyLuc	116160065	AAAAUGGAACAACUUUACCga	GGUAAAGUUGUUCCAUUUU	-3.3	-0.9	0	1	5	2	-30.6	83.6	14.4	7	Ia	31.6	72.3	94.5	Luciferase reporter assay	CHO-K1;HeLa;E14TG2a ;S2	50nM	24h	Guidelines for the selection of highly effective siRNA sequences for mammalian and chick RNA interference	14769950	2004	Nucleic Acids Research	2004/3/1
MC2507	U47298	Ui-Tei	FireflyLuc	116160065	UACAUAACCGGACAUAAUCau	GAUUAUGUCCGGUUAUGUA	-2.4	-1.3	0.9	1	2	4	-33.6	80.3	9.8	7	Ia	36.8	73.5	96.8	Luciferase reporter assay	CHO-K1;HeLa;E14TG2a ;S2	50nM	24h	Guidelines for the selection of highly effective siRNA sequences for mammalian and chick RNA interference	14769950	2004	Nucleic Acids Research	2004/3/1
MC2508	U47298	Ui-Tei	FireflyLuc	116160065	AGAAUGUAGCCAUCCAUCCuu	GGAUGGAUGGCUACAUUCU	-3.3	-2.1	-4	3	3	3	-38.7	69.2	5.1	6	Ia	47.4	68.9	97.4	Luciferase reporter assay	CHO-K1;HeLa;E14TG2a ;S2	50nM	24h	Guidelines for the selection of highly effective siRNA sequences for mammalian and chick RNA interference	14769950	2004	Nucleic Acids Research	2004/3/1
MC2509	U47298	Ui-Tei	FireflyLuc	116160065	UUAAUCAGAGACUUCAGGCgg	GCCUGAAGUCUCUGAUUAA	-3.4	-0.9	0.8	0	6	3	-36.2	86.6	9.7	8	Ia	42.1	81.5	95.6	Luciferase reporter assay	CHO-K1;HeLa;E14TG2a ;S2	50nM	24h	Guidelines for the selection of highly effective siRNA sequences for mammalian and chick RNA interference	14769950	2004	Nucleic Acids Research	2004/3/1
MC2510	U47298	Ui-Tei	FireflyLuc	116160065	CGGCGGCGGGAAGUUCACCgg	GGUGAACUUCCCGCCGCCG	-3.3	-2.4	-4.5	1	0	10	-45.7	24.8	10	-2	II	73.7	39.1	14.5	Luciferase reporter assay	CHO-K1;HeLa;E14TG2a ;S2	50nM	24h	Guidelines for the selection of highly effective siRNA sequences for mammalian and chick RNA interference	14769950	2004	Nucleic Acids Research	2004/3/1
MC2511	U47298	Ui-Tei	FireflyLuc	116160065	AAACAACAACGGCGGCGGGaa	CCCGCCGCCGUUGUUGUUU	-3.3	-0.9	1.6	1	5	10	-41.6	36.2	5.1	4	Ia	63.2	46.9	42.3	Luciferase reporter assay	CHO-K1;HeLa;E14TG2a ;S2	50nM	24h	Guidelines for the selection of highly effective siRNA sequences for mammalian and chick RNA interference	14769950	2004	Nucleic Acids Research	2004/3/1
MC2512	U47298	Ui-Tei	FireflyLuc	116160065	CAAAACAACAACGGCGGCGgg	CGCCGCCGUUGUUGUUUUG	-2.4	-2.1	1.9	-1	2	8	-38	48.7	0.7	5	II	57.9	56.5	51.3	Luciferase reporter assay	CHO-K1;HeLa;E14TG2a ;S2	50nM	24h	Guidelines for the selection of highly effective siRNA sequences for mammalian and chick RNA interference	14769950	2004	Nucleic Acids Research	2004/3/1
MC2513	NM_001632	Khovorova	SEAP	250	CAGAAGUCCGGGUUCUCCUcc	AGGAGAACCCGGACUUCUG	-2.1	-2.1	-2.7	1	0	5	-41.9	60.3	-0.9	2	II	57.9	51.8	81	Luciferase reporter assay	HEK293	0.25ug/Ml	24h	Functional siRNAs and miRNAs Exhibit Strand Biasunctional siRNAs and miRNAs Exhibit Strand Bias	14567918	2003	Cell	2003/10/17
MC2514	NM_001632	Khovorova	SEAP	250	CCCAGGAAGAUGAUGAGGUuc	ACCUCAUCAUCUUCCUGGG	-2.2	-3.3	-0.3	0	-1	3	-40.7	44.7	-6.2	3	III	52.6	42.4	49	Luciferase reporter assay	HEK293	0.25ug/Ml	24h	Functional siRNAs and miRNAs Exhibit Strand Biasunctional siRNAs and miRNAs Exhibit Strand Bias	14567918	2003	Cell	2003/10/17
MC2515	NM_001632	Khovorova	SEAP	250	ACUGUCUGGCACAUGUUUGuc	CAAACAUGUGCCAGACAGU	-2.1	-2.2	0	3	3	3	-37.6	70.2	-0.3	6	Ib	47.4	57.6	88	Luciferase reporter assay	HEK293	0.25ug/Ml	24h	Functional siRNAs and miRNAs Exhibit Strand Biasunctional siRNAs and miRNAs Exhibit Strand Bias	14567918	2003	Cell	2003/10/17
MC2516	NM_001632	Khovorova	SEAP	250	GGCGAGGCGUGCUGCACUCgu	GAGUGCAGCACGCCUCGCC	-2.4	-3.3	-0.7	0	0	4	-46.8	25.7	7.8	1	II	73.7	32.6	-5	Luciferase reporter assay	HEK293	0.25ug/Ml	24h	Functional siRNAs and miRNAs Exhibit Strand Biasunctional siRNAs and miRNAs Exhibit Strand Bias	14567918	2003	Cell	2003/10/17
MC2517	NM_001632	Khovorova	SEAP	250	CAGCCAUUCCUGCACCAGAuu	UCUGGUGCAGGAAUGGCUG	-2.4	-2.1	-0.4	2	-3	3	-42.5	45.9	-3.4	1	III	57.9	40.1	30	Luciferase reporter assay	HEK293	0.25ug/Ml	24h	Functional siRNAs and miRNAs Exhibit Strand Biasunctional siRNAs and miRNAs Exhibit Strand Bias	14567918	2003	Cell	2003/10/17
MC2518	NM_001632	Khovorova	SEAP	250	GAACAUGAUCGUCUCAGUCag	GACUGAGACGAUCAUGUUC	-2.4	-2.4	-0.2	1	3	2	-37	64	17.9	4	II	47.4	52.6	85	Luciferase reporter assay	HEK293	0.25ug/Ml	24h	Functional siRNAs and miRNAs Exhibit Strand Biasunctional siRNAs and miRNAs Exhibit Strand Bias	14567918	2003	Cell	2003/10/17
MC2519	NM_001632	Khovorova	SEAP	250	CUGGUGAGCUGGCCCGCCCuc	GGGCGGGCCAGCUCACCAG	-3.3	-2.1	-5.5	0	1	9	-49.6	35.3	7.8	1	II	78.9	51.9	20	Luciferase reporter assay	HEK293	0.25ug/Ml	24h	Functional siRNAs and miRNAs Exhibit Strand Biasunctional siRNAs and miRNAs Exhibit Strand Bias	14567918	2003	Cell	2003/10/17
MC2520	NM_001632	Khovorova	SEAP	250	GUGGGAGUGGUCGGCAGUGac	CACUGCCGACCACUCCCAC	-2.1	-2.2	1.9	0	1	4	-45.2	21.8	-2.4	1	II	68.4	39.2	-10	Luciferase reporter assay	HEK293	0.25ug/Ml	24h	Functional siRNAs and miRNAs Exhibit Strand Biasunctional siRNAs and miRNAs Exhibit Strand Bias	14567918	2003	Cell	2003/10/17
MC2521	NM_001632	Khovorova	SEAP	250	AACAUCCGGCCGGGCGCCGuc	CGGCGCCCGGCCGGAUGUU	-2.4	-0.9	-6.4	1	4	14	-48.3	29.8	-2.4	3	Ib	78.9	48	60	Luciferase reporter assay	HEK293	0.25ug/Ml	24h	Functional siRNAs and miRNAs Exhibit Strand Biasunctional siRNAs and miRNAs Exhibit Strand Bias	14567918	2003	Cell	2003/10/17
MC2522	NM_001632	Khovorova	SEAP	250	UCGCUCUCGGUAACAUCCGgc	CGGAUGUUACCGAGAGCGA	-2.4	-2.4	-2.5	3	3	3	-40.8	53	-2.6	3	II	57.9	66.9	32	Luciferase reporter assay	HEK293	0.25ug/Ml	24h	Functional siRNAs and miRNAs Exhibit Strand Biasunctional siRNAs and miRNAs Exhibit Strand Bias	14567918	2003	Cell	2003/10/17
MC2523	U47298	Reynolds	Firefly luciferase	116160065	CUUGACUGGCGACGUAAUCca	GAUUACGUCGCCAGUCAAG	-2.4	-2.1	-0.8	0	0	4	-37.9	53	10.5	4	II	52.6	48.1	96	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2524	U47298	Reynolds	Firefly luciferase	116160065	UGCGUCGAGUUUUCCGGUAag	UACCGGAAAACUCGACGCA	-1.3	-2.1	-0.2	1	-1	4	-39.2	56.2	-0.7	5	II	52.6	46.6	95.9	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2525	U47298	Reynolds	Firefly luciferase	116160065	UCUGAUUUUUCUUGCGUCGag	CGACGCAAGAAAAAUCAGA	-2.4	-2.4	1	0	3	3	-34	80.5	3.4	7	Ia	42.1	68.9	95.9	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2526	U47298	Reynolds	Firefly luciferase	116160065	AACUCCUCCGCGCAACUUUuu	AAAGUUGCGCGGAGGAGUU	-0.9	-0.9	0.8	3	0	6	-39.4	64.7	-3.9	6	II	52.6	51.5	95.5	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2527	U47298	Reynolds	Firefly luciferase	116160065	UCGUCCACAAACACAACUCcu	GAGUUGUGUUUGUGGACGA	-2.4	-2.4	-0.4	0	2	2	-37.1	72.1	4.8	6	II	47.4	68	95.3	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2528	U47298	Reynolds	Firefly luciferase	116160065	UCUCUCUGAUUUUUCUUGCgu	GCAAGAAAAAUCAGAGAGA	-3.4	-2.4	1	2	4	2	-33.6	93	12.8	7	Ib	36.8	70.3	95.1	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2529	U47298	Reynolds	Firefly luciferase	116160065	UUUCCGGUAAGACCUUUCGgu	CGAAAGGUCUUACCGGAAA	-2.4	-0.9	-1.5	1	4	4	-36.3	78.8	2.4	7	II	47.4	73.9	95	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2530	U47298	Reynolds	Firefly luciferase	116160065	CUUGCGUCGAGUUUUCCGGua	CCGGAAAACUCGACGCAAG	-3.3	-2.1	-0.2	1	3	4	-38.7	69.5	3.4	3	II	57.9	57.7	94.9	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2531	U47298	Reynolds	Firefly luciferase	116160065	UCCGGUAAGACCUUUCGGUac	ACCGAAAGGUCUUACCGGA	-2.2	-2.4	-4.7	1	2	4	-40	60.3	-6.3	4	II	52.6	57.7	94.7	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2532	U47298	Reynolds	Firefly luciferase	116160065	UUUUCUUGCGUCGAGUUUUcc	AAAACUCGACGCAAGAAAA	-0.9	-0.9	0.9	2	1	3	-32.4	84.8	-6.3	8	II	36.8	69.1	94.6	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2533	U47298	Reynolds	Firefly luciferase	116160065	CGUCGAGUUUUCCGGUAAGac	CUUACCGGAAAACUCGACG	-2.1	-2.4	-0.2	-1	-1	4	-36.7	42.7	-2	2	II	52.6	32.8	94.3	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2534	U47298	Reynolds	Firefly luciferase	116160065	UGACUGGCGACGUAAUCCAcg	UGGAUUACGUCGCCAGUCA	-2.1	-2.1	-0.8	2	1	4	-40.3	53.2	-6.1	7	II	52.6	58.2	93.6	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2535	U47298	Reynolds	Firefly luciferase	116160065	ACAACUCCUCCGCGCAACUuu	AGUUGCGCGGAGGAGUUGU	-2.1	-2.2	0.8	0	1	6	-41.9	48.5	-3.9	3	II	57.9	46.7	93.6	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2536	U47298	Reynolds	Firefly luciferase	116160065	CCACAAACACAACUCCUCCgc	GGAGGAGUUGUGUUUGUGG	-3.3	-3.3	2.7	0	1	2	-38.8	53.3	15.1	4	II	52.6	52.2	93.2	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2537	U47298	Reynolds	Firefly luciferase	116160065	UCUUUUUCCGUCAUCGUCUuu	AGACGAUGACGGAAAAAGA	-2.1	-2.4	0.3	2	2	3	-35.5	85.2	-6.6	8	II	42.1	71.7	93.1	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2538	U47298	Reynolds	Firefly luciferase	116160065	AAGACCUUUCGGUACUUCGuc	CGAAGUACCGAAAGGUCUU	-2.4	-0.9	-4.9	2	3	3	-36.4	81.6	0	5	Ib	47.4	68.3	93.1	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2539	U47298	Reynolds	Firefly luciferase	116160065	UACUUGACUGGCGACGUAAuc	UUACGUCGCCAGUCAAGUA	-0.9	-1.3	1.3	0	-1	4	-37.9	64	-6.1	8	II	47.4	55.1	92.9	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2540	U47298	Reynolds	Firefly luciferase	116160065	UUCUUGCGUCGAGUUUUCCgg	GGAAAACUCGACGCAAGAA	-3.3	-0.9	0.9	0	4	3	-36.3	75.9	9.7	7	Ib	47.4	68.6	92.7	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2541	U47298	Reynolds	Firefly luciferase	116160065	CCUUUAUGAGGAUCUCUCUga	AGAGAGAUCCUCAUAAAGG	-2.1	-3.3	-2.3	0	-2	2	-36.5	70.9	-6	4	II	42.1	44.3	92.6	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2542	U47298	Reynolds	Firefly luciferase	116160065	ACAAACACAACUCCUCCGCgc	GCGGAGGAGUUGUGUUUGU	-3.4	-2.2	0.7	1	4	4	-39.2	64.1	13.2	7	Ia	52.6	62.8	92.3	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2543	U47298	Reynolds	Firefly luciferase	116160065	UAUGAGGAUCUCUCUGAUUuu	AAUCAGAGAGAUCCUCAUA	-0.9	-1.3	-2.3	0	1	2	-35.8	70.2	-3.6	6	II	36.8	63.7	91.7	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2544	U47298	Reynolds	Firefly luciferase	116160065	AUCCACGAUCUCUUUUUCCgu	GGAAAAAGAGAUCGUGGAU	-3.3	-1.1	1.2	2	4	2	-35.3	76.3	10.1	6	II	42.1	66.9	91.3	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2545	U47298	Reynolds	Firefly luciferase	116160065	UAAUCCACGAUCUCUUUUUcc	AAAAAGAGAUCGUGGAUUA	-0.9	-1.3	0.4	1	1	2	-31.8	93.1	-6.3	9	II	31.6	70.2	91.2	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2546	U47298	Reynolds	Firefly luciferase	116160065	UACUUCGUCCACAAACACAac	UGUGUUUGUGGACGAAGUA	-2.1	-1.3	-0.4	1	0	2	-36	72.9	-6.4	7	II	42.1	62.9	90.8	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2547	U47298	Reynolds	Firefly luciferase	116160065	AUUUUUCUUGCGUCGAGUUuu	AACUCGACGCAAGAAAAAU	-0.9	-1.1	0.9	1	2	3	-32.6	83.1	-6.3	6	II	36.8	57.1	90.2	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2548	U47298	Reynolds	Firefly luciferase	116160065	CUUCGUCCACAAACACAACuc	GUUGUGUUUGUGGACGAAG	-2.2	-2.1	-0.5	0	0	2	-35.6	55.5	5.1	2	II	47.4	46.6	90.1	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2549	U47298	Reynolds	Firefly luciferase	116160065	GAGUUUUCCGGUAAGACCUuu	AGGUCUUACCGGAAAACUC	-2.1	-2.4	-1.5	2	0	4	-37.3	71.5	-3.5	3	II	47.4	54	90.1	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2550	U47298	Reynolds	Firefly luciferase	116160065	GACCUUUCGGUACUUCGUCca	GACGAAGUACCGAAAGGUC	-2.4	-2.4	-4.9	3	2	3	-38	61.1	12.1	2	II	52.6	50.8	89.7	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2551	U47298	Reynolds	Firefly luciferase	116160065	UGCUCCAAAACAACAACGGcg	CCGUUGUUGUUUUGGAGCA	-3.3	-2.1	-0.5	0	3	3	-36.4	67	-4.9	6	II	47.4	65.8	89.3	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2552	U47298	Reynolds	Firefly luciferase	116160065	UUUCCGUGCUCCAAAACAAca	UUGUUUUGGAGCACGGAAA	-0.9	-0.9	-1.4	3	1	3	-35.4	63.3	-11	5	II	42.1	57.5	89.2	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2553	U47298	Reynolds	Firefly luciferase	116160065	ACGAUCUCUUUUUCCGUCAuc	UGACGGAAAAAGAGAUCGU	-2.1	-2.2	0.6	2	-1	3	-35.5	76	-0.7	6	II	42.1	53.7	88.8	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2554	U47298	Reynolds	Firefly luciferase	116160065	UCGCGGUUGUUACUUGACUgg	AGUCAAGUAACAACCGCGA	-2.1	-2.4	1.1	3	1	5	-37.5	59.6	0.8	4	II	47.4	57.9	88.5	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2555	U47298	Reynolds	Firefly luciferase	116160065	UUUCGCGGUUGUUACUUGAcu	UCAAGUAACAACCGCGAAA	-2.4	-0.9	1.2	1	1	5	-35	73.7	-0.7	7	II	42.1	58.3	88.5	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2556	U47298	Reynolds	Firefly luciferase	116160065	UGAGGAUCUCUCUGAUUUUuc	AAAAUCAGAGAGAUCCUCA	-0.9	-2.1	-2.3	0	0	2	-35.2	64.8	-6.3	5	II	36.8	55.8	88.4	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2557	U47298	Reynolds	Firefly luciferase	116160065	UUUCCGUCAUCGUCUUUCCgu	GGAAAGACGAUGACGGAAA	-3.3	-0.9	0.3	2	4	3	-36.7	83.5	5.1	7	Ib	47.4	73.7	87.6	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2558	U47298	Reynolds	Firefly luciferase	116160065	UCUCUGAUUUUUCUUGCGUcg	ACGCAAGAAAAAUCAGAGA	-2.2	-2.4	1	1	3	3	-33.7	79.2	3.8	6	II	36.8	61.5	87.6	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2559	U47298	Reynolds	Firefly luciferase	116160065	GUCCACAAACACAACUCCUcc	AGGAGUUGUGUUUGUGGAC	-2.1	-2.2	1.5	1	0	2	-37.7	53.4	-3.9	3	III	47.4	46.1	87.5	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2560	U47298	Reynolds	Firefly luciferase	116160065	ACUGGCGACGUAAUCCACGau	CGUGGAUUACGUCGCCAGU	-2.4	-2.2	-1.4	2	4	4	-40.4	45.9	-0.3	2	II	57.9	60.9	87.1	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2561	U47298	Reynolds	Firefly luciferase	116160065	AAACACAACUCCUCCGCGCaa	GCGCGGAGGAGUUGUGUUU	-3.4	-0.9	-2.6	3	5	6	-40.7	56	5.4	4	Ia	57.9	64.3	86.8	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2562	U47298	Reynolds	Firefly luciferase	116160065	AGGAUCUCUCUGAUUUUUCuu	GAAAAAUCAGAGAGAUCCU	-2.4	-2.1	0.7	2	2	2	-34	82.7	7.1	6	Ib	36.8	63.6	86.8	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2563	U47298	Reynolds	Firefly luciferase	116160065	ACUUUUUCGCGGUUGUUACuu	GUAACAACCGCGAAAAAGU	-2.2	-2.2	0.9	3	3	5	-33.6	88.8	9.7	7	Ia	42.1	57.8	85.5	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2564	U47298	Reynolds	Firefly luciferase	116160065	GUUACUUGACUGGCGACGUaa	ACGUCGCCAGUCAAGUAAC	-2.2	-2.2	1.9	1	1	4	-38.8	58.8	-4	4	II	52.6	46.3	84.1	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2565	U47298	Reynolds	Firefly luciferase	116160065	GACGUAAUCCACGAUCUCUuu	AGAGAUCGUGGAUUACGUC	-2.1	-2.4	-0.1	1	-1	2	-37.4	58.2	-4	4	II	47.4	45.2	82.8	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2566	U47298	Reynolds	Firefly luciferase	116160065	UCCGUGCUCCAAAACAACAac	UGUUGUUUUGGAGCACGGA	-2.1	-2.4	-0.3	1	-1	3	-37.9	55.6	-4	4	II	47.4	55.2	82.5	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2567	U47298	Reynolds	Firefly luciferase	116160065	UCUCUUUUUCCGUCAUCGUcu	ACGAUGACGGAAAAAGAGA	-2.2	-2.4	0.3	2	2	3	-35.5	78	-6.3	6	II	42.1	60.9	80.7	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2568	U47298	Reynolds	Firefly luciferase	116160065	CGGUAAGACCUUUCGGUACuu	GUACCGAAAGGUCUUACCG	-2.2	-2.4	-4.9	0	-2	3	-37.8	57.5	11.1	3	II	52.6	41.3	80.4	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2569	U47298	Reynolds	Firefly luciferase	116160065	GGUUGUUACUUGACUGGCGac	CGCCAGUCAAGUAACAACC	-2.4	-3.3	1.1	2	2	4	-38.1	58.7	-2.6	3	II	52.6	48.1	79.5	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2570	U47298	Reynolds	Firefly luciferase	116160065	CCUCCGCGCAACUUUUUCGcg	CGAAAAAGUUGCGCGGAGG	-2.4	-3.3	1.5	1	1	6	-38.4	62.9	0.3	2	II	57.9	47.2	78.6	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2571	U47298	Reynolds	Firefly luciferase	116160065	UUGGCCUUUAUGAGGAUCUcu	AGAUCCUCAUAAAGGCCAA	-2.1	-0.9	-0.5	0	1	4	-37.2	75.1	-6.6	7	II	42.1	71	78.2	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2572	U47298	Reynolds	Firefly luciferase	116160065	UUUCGGUACUUCGUCCACAaa	UGUGGACGAAGUACCGAAA	-2.1	-0.9	-0.7	3	2	3	-37.7	62.1	-3.8	6	II	47.4	64.9	77.8	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2573	U47298	Reynolds	Firefly luciferase	116160065	UUUUUCGCGGUUGUUACUUga	AAGUAACAACCGCGAAAAA	-0.9	-0.9	1.2	1	3	5	-32.3	83.6	1.4	8	II	36.8	67	76.6	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2574	U47298	Reynolds	Firefly luciferase	116160065	CUCCAAAACAACAACGGCGgc	CGCCGUUGUUGUUUUGGAG	-2.4	-2.1	-0.7	1	1	5	-36.7	51.5	-1.9	4	II	52.6	57.9	74.8	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2575	U47298	Reynolds	Firefly luciferase	116160065	UUUUUCCGUCAUCGUCUUUcc	AAAGACGAUGACGGAAAAA	-0.9	-0.9	0.3	-1	1	3	-32.8	84.4	3.8	8	II	36.8	57.1	73.9	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2576	U47298	Reynolds	Firefly luciferase	116160065	UCCGUCAUCGUCUUUCCGUgc	ACGGAAAGACGAUGACGGA	-2.2	-2.4	-1	1	2	3	-39.5	66.9	-4	4	II	52.6	60.2	73.8	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2577	U47298	Reynolds	Firefly luciferase	116160065	GUUUUCCGGUAAGACCUUUcg	AAAGGUCUUACCGGAAAAC	-0.9	-2.2	-1.5	1	-1	4	-34.6	61	-1.7	4	II	42.1	38.7	71.1	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2578	U47298	Reynolds	Firefly luciferase	116160065	CCUUUCGGUACUUCGUCCAca	UGGACGAAGUACCGAAAGG	-2.1	-3.3	-3.4	-1	-2	3	-38.8	63.7	-5.1	4	III	52.6	40.3	70.3	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2579	U47298	Reynolds	Firefly luciferase	116160065	GAUCUCUCUGAUUUUUCUUgc	AAGAAAAAUCAGAGAGAUC	-0.9	-2.4	0.7	2	1	1	-31.6	90.6	3.7	4	II	31.6	48.7	68.1	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2580	U47298	Reynolds	Firefly luciferase	116160065	GCGACGUAAUCCACGAUCUcu	AGAUCGUGGAUUACGUCGC	-2.1	-3.4	-0.6	1	-2	3	-38.7	52.3	-11.3	3	III	52.6	39.9	67	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2581	U47298	Reynolds	Firefly luciferase	116160065	GCGGUUGUUACUUGACUGGcg	CCAGUCAAGUAACAACCGC	-3.3	-3.4	1.1	-1	0	4	-38.1	56.9	0.7	4	II	52.6	44.4	66.1	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2582	U47298	Reynolds	Firefly luciferase	116160065	GUAAGACCUUUCGGUACUUcg	AAGUACCGAAAGGUCUUAC	-0.9	-2.2	-4.9	-1	0	3	-35.1	46.1	-6.3	2	II	42.1	36.3	64.3	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2583	U47298	Reynolds	Firefly luciferase	116160065	AACGGCGGCGGGAAGUUCAcc	UGAACUUCCCGCCGCCGUU	-2.1	-0.9	1.6	2	0	10	-43.3	41.3	-6.3	4	II	63.2	47.5	63.3	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2584	U47298	Reynolds	Firefly luciferase	116160065	UCGAGUUUUCCGGUAAGACcu	GUCUUACCGGAAAACUCGA	-2.2	-2.4	-0.2	1	3	4	-36.7	67	7.4	5	Ib	47.4	62.1	61	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2585	U47298	Reynolds	Firefly luciferase	116160065	CCACGAUCUCUUUUUCCGUca	ACGGAAAAAGAGAUCGUGG	-2.2	-3.3	0.3	1	0	3	-36.4	57.8	-0.6	2	III	47.4	42.8	58.8	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2586	U47298	Reynolds	Firefly luciferase	116160065	AUCGUCUUUCCGUGCUCCAaa	UGGAGCACGGAAAGACGAU	-2.1	-1.1	-1	1	1	3	-40.1	61.1	-6.1	4	II	52.6	51.3	52.2	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2587	U47298	Reynolds	Firefly luciferase	116160065	GAUCUCUUUUUCCGUCAUCgu	GAUGACGGAAAAAGAGAUC	-2.4	-2.4	2.6	1	1	3	-34.4	69	7.5	4	II	42.1	49	47.6	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2588	U47298	Reynolds	Firefly luciferase	116160065	CGUAAUCCACGAUCUCUUUuu	AAAGAGAUCGUGGAUUACG	-0.9	-2.4	0.4	-1	-3	2	-34.6	67	-3.3	4	II	42.1	37.6	47.4	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2589	U47298	Reynolds	Firefly luciferase	116160065	CAACAACGGCGGCGGGAAGuu	CUUCCCGCCGCCGUUGUUG	-2.1	-2.1	1.6	0	0	10	-43	26.4	3.1	2	II	68.4	30.6	47.2	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2590	U47298	Reynolds	Firefly luciferase	116160065	UUGUUACUUGACUGGCGACgu	GUCGCCAGUCAAGUAACAA	-2.2	-0.9	1.1	-1	3	4	-37.2	71.3	7.4	6	Ia	47.4	60.7	44.9	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2591	U47298	Reynolds	Firefly luciferase	116160065	UGGCGACGUAAUCCACGAUcu	AUCGUGGAUUACGUCGCCA	-1.1	-2.1	-1.4	1	0	4	-39.6	51	3.8	3	II	52.6	43.8	44.2	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2592	U47298	Reynolds	Firefly luciferase	116160065	AACAACAACGGCGGCGGGAag	UCCCGCCGCCGUUGUUGUU	-2.4	-0.9	1.6	1	1	10	-43.1	37.8	-3.4	5	II	63.2	43	43.8	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2593	U47298	Reynolds	Firefly luciferase	116160065	CGUCAUCGUCUUUCCGUGCuc	GCACGGAAAGACGAUGACG	-3.4	-2.4	-1	0	0	3	-39.3	56.5	11.1	1	II	57.9	46.1	39.2	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2594	U47298	Reynolds	Firefly luciferase	116160065	CUCCUCCGCGCAACUUUUUcg	AAAAAGUUGCGCGGAGGAG	-0.9	-2.1	1.5	1	-3	6	-38.1	51.7	-10.9	3	III	52.6	37.8	38.8	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2595	U47298	Reynolds	Firefly luciferase	116160065	GGCCUUUAUGAGGAUCUCUcu	AGAGAUCCUCAUAAAGGCC	-2.1	-3.3	-0.7	2	-2	4	-38.7	58.1	-1.7	3	III	47.4	41.3	38.7	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2596	U47298	Reynolds	Firefly luciferase	116160065	GGUACUUCGUCCACAAACAca	UGUUUGUGGACGAAGUACC	-2.1	-3.3	-0.4	2	-2	2	-37.2	59.2	-11	3	II	47.4	39.3	35.9	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2597	U47298	Reynolds	Firefly luciferase	116160065	CGUGCUCCAAAACAACAACgg	GUUGUUGUUUUGGAGCACG	-2.2	-2.4	-0.3	-1	-1	2	-35.3	59.1	10.1	2	II	47.4	43.5	32.6	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2598	U47298	Reynolds	Firefly luciferase	116160065	UCCGCGCAACUUUUUCGCGgu	CGCGAAAAAGUUGCGCGGA	-2.4	-2.4	-4.4	0	4	6	-38.8	60.2	5.4	1	II	57.9	58.4	32.1	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2599	U47298	Reynolds	Firefly luciferase	116160065	CGCGCAACUUUUUCGCGGUug	ACCGCGAAAAAGUUGCGCG	-2.2	-2.4	-3.9	-1	-2	5	-38.6	47.9	-3	-1	III	57.9	34.3	29.9	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2600	U47298	Reynolds	Firefly luciferase	116160065	ACACAACUCCUCCGCGCAAcu	UUGCGCGGAGGAGUUGUGU	-0.9	-2.2	-2.7	2	0	6	-41.9	32	-1	2	II	57.9	31.8	24.9	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2601	U47298	Reynolds	Firefly luciferase	116160065	UCAUCGUCUUUCCGUGCUCca	GAGCACGGAAAGACGAUGA	-2.4	-2.4	-1	0	3	3	-39.2	61.5	7.5	5	Ib	52.6	61.7	20.3	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2602	U47298	Reynolds	Firefly luciferase	116160065	ACAACGGCGGCGGGAAGUUca	AACUUCCCGCCGCCGUUGU	-0.9	-2.2	1.6	1	1	10	-43.1	27.6	-6.3	4	II	63.2	39	18.4	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2603	U47298	Reynolds	Firefly luciferase	116160065	CCAAAACAACAACGGCGGCgg	GCCGCCGUUGUUGUUUUGG	-3.4	-3.3	0.4	-2	1	7	-38.9	35.9	12.8	2	II	57.9	37.5	13.8	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2604	U47298	Reynolds	Firefly luciferase	116160065	CGCAACUUUUUCGCGGUUGuu	CAACCGCGAAAAAGUUGCG	-2.1	-2.4	-3.5	0	-2	5	-35.8	56.9	-1.7	3	II	52.6	44	-1.3	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2605	U47298	Reynolds	Firefly luciferase	116160065	CAACUUUUUCGCGGUUGUUac	AACAACCGCGAAAAAGUUG	-0.9	-2.1	-0.3	0	-1	5	-33.1	62.8	-8.3	4	II	42.1	43.3	-5.7	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2606	U47298	Reynolds	Firefly luciferase	116160065	CGUCUUUCCGUGCUCCAAAac	UUUGGAGCACGGAAAGACG	-0.9	-2.4	-0.3	2	-3	3	-38.4	57.9	-1	3	II	52.6	37.2	-10.4	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2607	U47298	Reynolds	Firefly luciferase	116160065	UCUUGGCCUUUAUGAGGAUcu	AUCCUCAUAAAGGCCAAGA	-1.1	-2.4	-0.5	-1	1	4	-37.2	55.1	-4	5	II	42.1	42.9	-12.8	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2608	U47298	Reynolds	Firefly luciferase	116160065	UCGGUACUUCGUCCACAAAca	UUUGUGGACGAAGUACCGA	-0.9	-2.4	-0.7	0	-2	3	-37.7	57.4	1.7	4	II	47.4	40.6	-18	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2609	U47298	Reynolds	Firefly luciferase	116160065	UCUUUCCGUGCUCCAAAACaa	GUUUUGGAGCACGGAAAGA	-2.2	-2.4	-1.4	0	2	3	-36.9	72.4	10.5	5	Ib	47.4	57	-27.8	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2610	M60857	Reynolds	Cyclophilin B	829639	CUCUCCUGUAGCUAAGGCCac	GGCCUUAGCUACAGGAGAG	-3.3	-2.1	-1.1	0	1	4	-41.9	66	3.1	2	II	57.9	56.4	94.6	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2611	M60857	Reynolds	Cyclophilin B	829639	UUUGUAGCCAAAUCCUUUCuc	GAAAGGAUUUGGCUACAAA	-2.4	-0.9	-0.5	1	3	3	-33.2	88.5	9.7	9	Ia	36.8	78.2	94.2	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2612	M60857	Reynolds	Cyclophilin B	829639	AAUCCUUUCUCUCCUGUAGcu	CUACAGGAGAGAAAGGAUU	-2.1	-0.9	1.8	4	3	2	-36.1	86.2	3.1	6	Ia	42.1	59.6	93.9	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2613	M60857	Reynolds	Cyclophilin B	829639	UAGCCAAAUCCUUUCUCUCcu	GAGAGAAAGGAUUUGGCUA	-2.4	-1.3	1.5	1	4	3	-36.1	80.1	10.4	5	Ib	42.1	70.6	93.4	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2614	M60857	Reynolds	Cyclophilin B	829639	CACCGUAGAUGCUCUUUCCuc	GGAAAGAGCAUCUACGGUG	-3.3	-2.1	0.2	0	0	3	-38.7	64.9	3.1	3	II	52.6	52.1	93.3	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2615	M60857	Reynolds	Cyclophilin B	829639	UCUCCGCCCUGGAUCAUGAag	UCAUGAUCCAGGGCGGAGA	-2.4	-2.4	-2.2	2	1	6	-43.7	55.2	-4	3	II	57.9	48	92.8	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2616	M60857	Reynolds	Cyclophilin B	829639	GAAGUCUCCGCCCUGGAUCau	GAUCCAGGGCGGAGACUUC	-2.4	-2.4	-2.2	2	2	6	-43.6	56.3	7.4	2	II	63.2	52.2	92.7	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2617	M60857	Reynolds	Cyclophilin B	829639	GUUCUCAUCGGGGAAGCGCuc	GCGCUUCCCCGAUGAGAAC	-3.4	-2.2	1	2	3	5	-42.5	48.1	7.4	3	II	63.2	50.5	92.7	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2618	M60857	Reynolds	Cyclophilin B	829639	UGUAGCCAAAUCCUUUCUCuc	GAGAAAGGAUUUGGCUACA	-2.4	-2.1	1.4	0	4	3	-35.9	77.6	9.8	6	II	42.1	65.4	92.3	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2619	M60857	Reynolds	Cyclophilin B	829639	GAUUACACGAUGGAAUUUGcu	CAAAUUCCAUCGUGUAAUC	-2.1	-2.4	2.9	1	1	2	-31.8	69	2.7	7	II	36.8	53.3	92.3	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2620	M60857	Reynolds	Cyclophilin B	829639	ACACGAUGGAAUUUGCUGUuu	ACAGCAAAUUCCAUCGUGU	-2.2	-2.2	1.8	4	2	2	-35.9	70.4	3.7	6	II	42.1	54.4	91.9	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2621	M60857	Reynolds	Cyclophilin B	829639	AUGCUCUUUCCUCCUGUGCca	GCACAGGAGGAAAGAGCAU	-3.4	-1.1	0.2	3	3	2	-40.4	75.1	10.5	6	Ib	52.6	64.3	90.8	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2622	M60857	Reynolds	Cyclophilin B	829639	AAAUUAUCCACUGUUUUUGga	CAAAAACAGUGGAUAAUUU	-2.1	-0.9	2.2	3	4	2	-28.3	98.5	3	9	Ia	26.3	71.1	90.2	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2623	M60857	Reynolds	Cyclophilin B	829639	UCAGUUUGAAGUUCUCAUCgg	GAUGAGAACUUCAAACUGA	-2.4	-2.4	0.4	1	2	1	-33.7	89.4	10.4	7	Ia	36.8	73.5	89.7	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2624	M60857	Reynolds	Cyclophilin B	829639	CCUGGUGAAGUCUCCGCCCug	GGGCGGAGACUUCACCAGG	-3.3	-3.3	-0.8	-1	1	6	-45.3	39.9	3.1	1	II	68.4	50.5	89	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2625	M60857	Reynolds	Cyclophilin B	829639	GAAGCGCUCACCGUAGAUGcu	CAUCUACGGUGAGCGCUUC	-2.1	-2.4	-0.7	1	2	4	-40.3	48.6	-2.4	2	II	57.9	46.2	89	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2626	M60857	Reynolds	Cyclophilin B	829639	UGAAGUCCUUGAUUACACGau	CGUGUAAUCAAGGACUUCA	-2.4	-2.1	1.5	0	4	2	-35.1	74.4	2.3	5	Ib	42.1	67.8	88.8	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2627	M60857	Reynolds	Cyclophilin B	829639	UCCGCCCUGGAUCAUGAAGuc	CUUCAUGAUCCAGGGCGGA	-2.1	-2.4	-1.4	1	1	6	-42.2	58.8	7.7	1	II	57.9	49.3	88.7	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2628	M60857	Reynolds	Cyclophilin B	829639	GCCAAAUCCUUUCUCUCCUgu	AGGAGAGAAAGGAUUUGGC	-2.1	-3.4	2.3	2	0	3	-38.1	62.7	6.5	3	II	47.4	40.6	88.4	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2629	M60857	Reynolds	Cyclophilin B	829639	UAUCCACUGUUUUUGGAACag	GUUCCAAAAACAGUGGAUA	-2.2	-1.3	-2.5	2	4	2	-33.3	85.9	12.8	4	Ib	36.8	62.7	88.1	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2630	M60857	Reynolds	Cyclophilin B	829639	AUCAUGAAGUCCUUGAUUAca	UAAUCAAGGACUUCAUGAU	-1.3	-1.1	0.7	2	0	2	-32.9	79.7	-6.1	7	II	31.6	55.5	87.9	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2631	M60857	Reynolds	Cyclophilin B	829639	AUCUCCCCUGGUGAAGUCUcc	AGACUUCACCAGGGGAGAU	-2.1	-1.1	-2.5	1	1	4	-41.8	63	-1	4	II	52.6	50.3	87.6	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2632	M60857	Reynolds	Cyclophilin B	829639	UUGAUUACACGAUGGAAUUug	AAUUCCAUCGUGUAAUCAA	-0.9	-0.9	1.5	-1	0	2	-31.8	83	-4	7	II	31.6	65.9	87.4	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2633	M60857	Reynolds	Cyclophilin B	829639	GUCCUUGAUUACACGAUGGaa	CCAUCGUGUAAUCAAGGAC	-3.3	-2.2	0.9	1	1	2	-36.5	63.6	-2.6	4	II	47.4	51.6	87.4	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2634	M60857	Reynolds	Cyclophilin B	829639	AAGUCCUUGAUUACACGAUgg	AUCGUGUAAUCAAGGACUU	-1.1	-0.9	1.5	3	1	2	-34.1	78.1	-3.5	6	II	36.8	55.8	86.7	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2635	M60857	Reynolds	Cyclophilin B	829639	UCUCAUCGGGGAAGCGCUCac	GAGCGCUUCCCCGAUGAGA	-2.4	-2.4	1	1	3	5	-43.9	39.5	7.5	4	Ib	63.2	54.7	86.5	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2636	M60857	Reynolds	Cyclophilin B	829639	UUACACGAUGGAAUUUGCUgu	AGCAAAUUCCAUCGUGUAA	-2.1	-0.9	1.1	1	4	2	-33.8	71.2	-1.5	7	II	36.8	68.7	86.4	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2637	M60857	Reynolds	Cyclophilin B	829639	AGUUUGAAGUUCUCAUCGGgg	CCGAUGAGAACUUCAAACU	-3.3	-2.1	0.1	2	4	3	-34.9	69.4	-2.4	6	Ia	42.1	59.5	85.1	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2638	M60857	Reynolds	Cyclophilin B	829639	CAAAUCCUUUCUCUCCUGUag	ACAGGAGAGAAAGGAUUUG	-2.2	-2.1	2.3	-1	0	2	-35.7	75.9	-0.6	5	II	42.1	47.9	84.9	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2639	M60857	Reynolds	Cyclophilin B	829639	UCUUUCCUCCUGUGCCAUCuc	GAUGGCACAGGAGGAAAGA	-2.4	-2.4	3	0	2	3	-40.6	67.9	7.4	6	Ib	52.6	59.1	84.9	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2640	M60857	Reynolds	Cyclophilin B	829639	UUUGAAGUUCUCAUCGGGGaa	CCCCGAUGAGAACUUCAAA	-3.3	-0.9	0.1	0	6	5	-37.2	65.1	0.1	7	Ia	47.4	72.9	84.7	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2641	M60857	Reynolds	Cyclophilin B	829639	UAAGGCCACAAAAUUAUCCac	GGAUAAUUUUGUGGCCUUA	-3.3	-1.3	0.9	1	5	4	-33.5	81.8	9.4	7	II	36.8	80.6	83.9	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2642	M60857	Reynolds	Cyclophilin B	829639	UCAUCGGGGAAGCGCUCACcg	GUGAGCGCUUCCCCGAUGA	-2.2	-2.4	0.7	0	3	5	-43.7	49.5	12.1	6	II	63.2	55.7	83.9	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2643	M60857	Reynolds	Cyclophilin B	829639	UGAAGUUCUCAUCGGGGAAgc	UUCCCCGAUGAGAACUUCA	-0.9	-2.1	0.1	0	0	5	-38.7	63.9	4	6	II	47.4	48.4	83.8	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2644	M60857	Reynolds	Cyclophilin B	829639	UGUUUUUGUAGCCAAAUCCuu	GGAUUUGGCUACAAAAACA	-3.3	-2.1	-1.3	1	3	3	-33	93.5	7.5	8	Ia	36.8	79.5	83.5	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2645	M60857	Reynolds	Cyclophilin B	829639	CCCUGGAUCAUGAAGUCCUug	AGGACUUCAUGAUCCAGGG	-2.1	-3.3	-2.1	0	-2	3	-40.7	49.8	-8.6	2	III	52.6	46	82.9	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2646	M60857	Reynolds	Cyclophilin B	829639	UUUUUGUAGCCAAAUCCUUuc	AAGGAUUUGGCUACAAAAA	-0.9	-0.9	-1.3	2	2	3	-31.7	78.3	-8.9	7	II	31.6	69.2	81.9	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2647	M60857	Reynolds	Cyclophilin B	829639	UAGCUAAGGCCACAAAAUUau	AAUUUUGUGGCCUUAGCUA	-0.9	-1.3	-1.6	2	0	4	-34.3	61.5	-3.9	5	II	36.8	60.3	81.3	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2648	M60857	Reynolds	Cyclophilin B	829639	CUCCCCUGGUGAAGUCUCCgc	GGAGACUUCACCAGGGGAG	-3.3	-2.1	-1.6	1	0	4	-44	46.8	2.8	1	II	63.2	46.7	80.9	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2649	M60857	Reynolds	Cyclophilin B	829639	UCCUCCUGUGCCAUCUCCCcu	GGGAGAUGGCACAGGAGGA	-3.3	-2.4	3	1	4	3	-45.4	64.1	2.4	4	II	63.2	66.8	80.4	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2650	M60857	Reynolds	Cyclophilin B	829639	AUCGGGGAAGCGCUCACCGua	CGGUGAGCGCUUCCCCGAU	-2.4	-1.1	-1.2	1	5	5	-44.9	41.1	2.4	2	II	68.4	60.6	80.2	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2651	M60857	Reynolds	Cyclophilin B	829639	UGGAAUUUGCUGUUUUUGUag	ACAAAAACAGCAAAUUCCA	-2.2	-2.1	4.5	2	1	2	-31.4	91.1	1.1	7	II	31.6	65.2	78.5	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2652	M60857	Reynolds	Cyclophilin B	829639	AUUUGCUGUUUUUGUAGCCaa	GGCUACAAAAACAGCAAAU	-3.3	-1.1	-1.9	1	5	3	-32.8	83.4	10.4	5	Ia	36.8	67.3	77.4	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2653	M60857	Reynolds	Cyclophilin B	829639	UUCUCUCCUGUAGCUAAGGcc	CCUUAGCUACAGGAGAGAA	-3.3	-0.9	-0.7	0	3	2	-38.5	70.7	0	5	Ib	47.4	67.9	77.2	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2654	M60857	Reynolds	Cyclophilin B	829639	CCCCUGGUGAAGUCUCCGCcc	GCGGAGACUUCACCAGGGG	-3.4	-3.3	-0.8	1	0	4	-45.3	44.8	7.7	2	II	68.4	44.7	76.6	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2655	M60857	Reynolds	Cyclophilin B	829639	CUCCUGUGCCAUCUCCCCUgg	AGGGGAGAUGGCACAGGAG	-2.1	-2.1	3	2	0	4	-45.1	56.2	4.1	2	III	63.2	48.7	76.1	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2656	M60857	Reynolds	Cyclophilin B	829639	UCCUUUCUCUCCUGUAGCUaa	AGCUACAGGAGAGAAAGGA	-2.1	-2.4	1.6	0	1	2	-39.6	70.6	-8.7	5	II	47.4	52.1	75.8	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2657	M60857	Reynolds	Cyclophilin B	829639	AUUAUCCACUGUUUUUGGAac	UCCAAAAACAGUGGAUAAU	-2.4	-1.1	-2.3	2	3	2	-32.2	90.5	1.6	5	II	31.6	51.9	75.3	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2658	M60857	Reynolds	Cyclophilin B	829639	AGAUGCUCUUUCCUCCUGUgc	ACAGGAGGAAAGAGCAUCU	-2.2	-2.1	1.1	2	2	2	-39.4	67.5	-1.6	6	II	47.4	54.4	74.5	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2659	M60857	Reynolds	Cyclophilin B	829639	CUGGAUCAUGAAGUCCUUGau	CAAGGACUUCAUGAUCCAG	-2.1	-2.1	-2.1	-1	0	2	-37.1	56.1	5.3	2	II	47.4	52	74.4	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2660	M60857	Reynolds	Cyclophilin B	829639	UGUGCCAUCUCCCCUGGUGaa	CACCAGGGGAGAUGGCACA	-2.1	-2.1	-1.5	1	3	4	-44.9	58.8	-2.3	3	II	63.2	57.3	73.8	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2661	M60857	Reynolds	Cyclophilin B	829639	GUAGUGCUUCAGUUUGAAGuu	CUUCAAACUGAAGCACUAC	-2.1	-2.2	-2	0	2	2	-34.4	70.1	4.6	2	II	42.1	46.7	73.1	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2662	M60857	Reynolds	Cyclophilin B	829639	CGCUCACCGUAGAUGCUCUuu	AGAGCAUCUACGGUGAGCG	-2.1	-2.4	-0.9	0	-2	3	-41.5	51.7	-3.9	1	III	57.9	32.3	71.7	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2663	M60857	Reynolds	Cyclophilin B	829639	GAAUUUGCUGUUUUUGUAGcc	CUACAAAAACAGCAAAUUC	-2.1	-2.4	2.8	0	2	2	-29.4	90.1	5.4	6	II	31.6	55.7	71.2	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2664	M60857	Reynolds	Cyclophilin B	829639	UUUCCUCCUGUGCCAUCUCcc	GAGAUGGCACAGGAGGAAA	-2.4	-0.9	3	1	4	3	-40.6	67.4	9.8	5	Ib	52.6	67.3	70.5	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2665	M60857	Reynolds	Cyclophilin B	829639	AGUGCUUCAGUUUGAAGUUcu	AACUUCAAACUGAAGCACU	-0.9	-2.1	-2.5	1	1	2	-34	72	-1	3	II	36.8	50.5	69.2	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2666	M60857	Reynolds	Cyclophilin B	829639	UUGCUGUUUUUGUAGCCAAau	UUGGCUACAAAAACAGCAA	-0.9	-0.9	-1.9	2	0	3	-33.8	73.1	-3.8	5	II	36.8	60.1	68	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2667	M60857	Reynolds	Cyclophilin B	829639	AAGUUCUCAUCGGGGAAGCgc	GCUUCCCCGAUGAGAACUU	-3.4	-0.9	1.2	1	3	5	-39.7	61.7	5.1	6	Ia	52.6	57.5	67.8	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2668	M60857	Reynolds	Cyclophilin B	829639	GGAUCAUGAAGUCCUUGAUua	AUCAAGGACUUCAUGAUCC	-1.1	-3.3	-0.4	1	-1	2	-36.4	69.8	1.5	4	II	42.1	32.5	66.4	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2669	M60857	Reynolds	Cyclophilin B	829639	AGCGCUCACCGUAGAUGCUcu	AGCAUCUACGGUGAGCGCU	-2.1	-2.1	-0.9	1	1	4	-42.5	46.7	-3.5	1	II	57.9	39.4	64.1	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2670	M60857	Reynolds	Cyclophilin B	829639	CAUGAAGUCCUUGAUUACAcg	UGUAAUCAAGGACUUCAUG	-2.1	-2.1	1.6	0	-2	2	-33.7	61	0	4	II	36.8	45.2	63.9	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2671	M60857	Reynolds	Cyclophilin B	829639	CUCCUGUAGCUAAGGCCACaa	GUGGCCUUAGCUACAGGAG	-2.2	-2.1	-5.8	1	0	4	-41.7	39.8	2.8	1	II	57.9	45.8	60.3	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2672	M60857	Reynolds	Cyclophilin B	829639	GUAGAUGCUCUUUCCUCCUgu	AGGAGGAAAGAGCAUCUAC	-2.1	-2.2	0.4	0	1	2	-38.6	62.1	1.8	4	II	47.4	52.5	58.9	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2673	M60857	Reynolds	Cyclophilin B	829639	CCGUAGAUGCUCUUUCCUCcu	GAGGAAAGAGCAUCUACGG	-2.4	-3.3	0.6	0	0	3	-38.9	57	8.1	3	II	52.6	48.8	58.4	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2674	M60857	Reynolds	Cyclophilin B	829639	GCUCUUUCCUCCUGUGCCAuc	UGGCACAGGAGGAAAGAGC	-2.1	-3.4	1.9	2	-1	3	-42.6	50.4	-8.5	2	II	57.9	32.9	55.9	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2675	M60857	Reynolds	Cyclophilin B	829639	AGGCCACAAAAUUAUCCACug	GUGGAUAAUUUUGUGGCCU	-2.2	-2.1	0.9	2	2	4	-35.6	68.3	12.7	3	II	42.1	50.6	55	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2676	M60857	Reynolds	Cyclophilin B	829639	UGUAGCUAAGGCCACAAAAuu	UUUUGUGGCCUUAGCUACA	-0.9	-2.1	-5.9	1	-1	4	-36.6	68	-3.7	5	II	42.1	52.5	52	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2677	M60857	Reynolds	Cyclophilin B	829639	CGCCCUGGAUCAUGAAGUCcu	GACUUCAUGAUCCAGGGCG	-2.4	-2.4	1	-1	-1	5	-41.1	40.7	3.1	0	II	57.9	34.6	51.2	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2678	M60857	Reynolds	Cyclophilin B	829639	CUCACCGUAGAUGCUCUUUcc	AAAGAGCAUCUACGGUGAG	-0.9	-2.1	-0.9	-1	-3	3	-37.5	67.2	-0.7	4	III	47.4	42	50.7	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2679	M60857	Reynolds	Cyclophilin B	829639	CAAAAUUAUCCACUGUUUUug	AAAACAGUGGAUAAUUUUG	-0.9	-2.1	2.1	0	-1	2	-28.3	83.2	-0.9	6	II	26.3	54.4	49.5	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2680	M60857	Reynolds	Cyclophilin B	829639	AGUCUCCGCCCUGGAUCAUga	AUGAUCCAGGGCGGAGACU	-1.1	-2.1	-2.2	2	1	6	-43.5	42.2	-3.3	2	II	57.9	31.5	48.5	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2681	M60857	Reynolds	Cyclophilin B	829639	UGGUGAAGUCUCCGCCCUGga	CAGGGCGGAGACUUCACCA	-2.1	-2.1	-0.9	-1	2	6	-44.1	41.2	0.1	4	Ib	63.2	55.7	46.8	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2682	M60857	Reynolds	Cyclophilin B	829639	CCUUGAUUACACGAUGGAAuu	UUCCAUCGUGUAAUCAAGG	-0.9	-3.3	1.5	0	-3	2	-35.2	55.3	-5.8	3	II	42.1	28.4	45.9	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2683	M60857	Reynolds	Cyclophilin B	829639	UGCUUCAGUUUGAAGUUCUca	AGAACUUCAAACUGAAGCA	-2.1	-2.1	-2.5	0	0	2	-34.2	76.1	-6.6	6	II	36.8	61.7	45.4	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2684	M60857	Reynolds	Cyclophilin B	829639	CCAUCUCCCCUGGUGAAGUcu	ACUUCACCAGGGGAGAUGG	-2.2	-3.3	-2.5	0	-1	4	-42.7	50	-3.6	0	III	57.9	37.7	41.9	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2685	M60857	Reynolds	Cyclophilin B	829639	GUGAAGUCUCCGCCCUGGAuc	UCCAGGGCGGAGACUUCAC	-2.4	-2.2	-1.9	1	-1	6	-44.4	42.5	-1	2	II	63.2	37.1	41.8	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2686	M60857	Reynolds	Cyclophilin B	829639	CUUCAGUUUGAAGUUCUCAuc	UGAGAACUUCAAACUGAAG	-2.1	-2.1	-2.1	1	-1	1	-33.2	69.5	1.6	4	II	36.8	51.1	41.7	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2687	M60857	Reynolds	Cyclophilin B	829639	GCCACAAAAUUAUCCACUGuu	CAGUGGAUAAUUUUGUGGC	-2.1	-3.4	2	0	0	3	-34.4	58.6	0	2	II	42.1	42.8	39.7	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2688	M60857	Reynolds	Cyclophilin B	829639	GCUAAGGCCACAAAAUUAUcc	AUAAUUUUGUGGCCUUAGC	-1.1	-3.4	1.2	1	-2	4	-33.3	56.5	-6.2	6	III	36.8	38.6	32.8	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2689	M60857	Reynolds	Cyclophilin B	829639	CUUUCUCUCCUGUAGCUAAgg	UUAGCUACAGGAGAGAAAG	-0.9	-2.1	1.6	0	-3	2	-36.1	72.7	-5.8	4	II	42.1	39.5	30.7	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2690	M60857	Reynolds	Cyclophilin B	829639	CCUGUGCCAUCUCCCCUGGug	CCAGGGGAGAUGGCACAGG	-3.3	-3.3	-1	-1	0	4	-46	43.3	1.1	1	II	68.4	39	21.4	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2691	M60857	Reynolds	Cyclophilin B	829639	CCGUAGUGCUUCAGUUUGAag	UCAAACUGAAGCACUACGG	-2.4	-3.3	0.5	0	-4	3	-37.1	47.5	-8	4	III	47.4	32.9	18.1	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2692	M60857	Reynolds	Cyclophilin B	829639	UGCCAUCUCCCCUGGUGAAgu	UUCACCAGGGGAGAUGGCA	-0.9	-2.1	-1.5	1	-1	4	-43.9	48.8	-5.8	2	II	57.9	35.9	17.6	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2693	M60857	Reynolds	Cyclophilin B	829639	CACAAAAUUAUCCACUGUUuu	AACAGUGGAUAAUUUUGUG	-0.9	-2.1	-0.1	-1	-2	2	-30.8	70.1	-3.2	5	II	31.6	50.7	16.3	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2694	M60857	Reynolds	Cyclophilin B	829639	CCUGUAGCUAAGGCCACAAaa	UUGUGGCCUUAGCUACAGG	-0.9	-3.3	-7.1	-1	-3	4	-40.2	44	-3.5	3	III	52.6	32.5	16	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2695	M60857	Reynolds	Cyclophilin B	829639	GCUGUUUUUGUAGCCAAAUcc	AUUUGGCUACAAAAACAGC	-1.1	-3.4	-1.3	1	-2	3	-32.8	63.4	-4	2	II	36.8	41.5	13.8	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2696	M60857	Reynolds	Cyclophilin B	829639	GAUGGAAUUUGCUGUUUUUgu	AAAAACAGCAAAUUCCAUC	-0.9	-2.4	4.5	-1	-1	2	-30.6	70.2	-6.3	4	II	31.6	38.5	7.6	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2697	M60857	Reynolds	Cyclophilin B	829639	ACGAUGGAAUUUGCUGUUUuu	AAACAGCAAAUUCCAUCGU	-0.9	-2.2	2.7	1	-1	2	-33.4	63.7	-1	6	II	36.8	47.3	7.3	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2698	M60857	Reynolds	Cyclophilin B	829639	GGGAAGCGCUCACCGUAGAug	UCUACGGUGAGCGCUUCCC	-2.4	-3.3	-0.1	1	-3	4	-43.7	31.4	-1	1	III	63.2	23.1	2.8	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2699	M60857	Reynolds	Cyclophilin B	829639	CGGGGAAGCGCUCACCGUAga	UACGGUGAGCGCUUCCCCG	-1.3	-2.4	-0.6	0	-4	5	-44.9	24.4	-2.7	0	III	68.4	28.7	-9.9	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2700	-	Reynolds	RenillaLuc	/	CACAACAUGUCGCCAUAAAua	UUUAUGGCGACAUGUUGUG	-0.9	-2.1	-2.8	0	-4	4	-34.8	58.4	-3	3	II	42.1	32.3	29.4	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2701	-	Reynolds	RenillaLuc	/	UUCAAACCAUGCAGUAAGAua	UCUUACUGCAUGGUUUGAA	-2.4	-0.9	0.8	-1	0	2	-34.5	64	-6	6	II	36.8	50.5	52.3	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2702	-	Reynolds	RenillaLuc	/	AAUCACAUCUACUACACUUuc	AAGUGUAGUAGAUGUGAUU	-0.9	-0.9	3.3	3	2	1	-32.8	80.1	-1.3	6	II	31.6	61.2	87.9	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2703	-	Reynolds	RenillaLuc	/	GUUCUAACUUUCUCAUGAUuu	AUCAUGAGAAAGUUAGAAC	-1.1	-2.2	1.1	1	0	1	-31.6	70	-6.3	4	II	31.6	40.4	47.3	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2704	-	Reynolds	RenillaLuc	/	CAAGAUAUGCUGCAAAUUCuu	GAAUUUGCAGCAUAUCUUG	-2.4	-2.1	2.2	0	0	2	-32.4	66.3	10.5	5	II	36.8	60.8	84.8	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2705	-	Reynolds	RenillaLuc	/	UAAUGUUGGACGACGAACUuc	AGUUCGUCGUCCAACAUUA	-2.1	-1.3	0.5	2	2	2	-35.5	75.5	-8.9	8	II	42.1	74	66.5	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2706	-	Reynolds	RenillaLuc	/	AUCAUCACUUGCACGUAGAua	UCUACGUGCAAGUGAUGAU	-2.4	-1.1	-0.4	1	0	2	-36.6	70.2	-8.7	6	II	42.1	52.7	89.5	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2707	-	Reynolds	RenillaLuc	/	CAUUUCAUCAGGUGCAUCUuc	AGAUGCACCUGAUGAAAUG	-2.1	-2.1	1.6	-1	-1	2	-35.9	81	-6	7	II	42.1	54.3	63.9	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2708	-	Reynolds	RenillaLuc	/	UCAUCCGUUUCCUUUGUUCug	GAACAAAGGAAACGGAUGA	-2.4	-2.4	2.6	0	3	3	-34.9	84.9	5	7	II	42.1	65.2	84.4	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2709	-	Reynolds	RenillaLuc	/	UCCUUCUUCAGAUUUGAUCaa	GAUCAAAUCUGAAGAAGGA	-2.4	-2.4	0	2	2	2	-34	96.7	9.7	7	Ib	36.8	70.1	90.9	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2710	-	Reynolds	RenillaLuc	/	UAUUAGGAAACUUCUUGGCac	GCCAAGAAGUUUCCUAAUA	-3.4	-1.3	1.8	0	5	3	-33.6	88.5	10.8	9	Ia	36.8	74.5	72.2	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2711	-	Reynolds	RenillaLuc	/	AAUGGUUCAAGAUAUGCUGca	CAGCAUAUCUUGAACCAUU	-2.1	-0.9	1.1	2	4	2	-33.6	79.8	0	6	Ia	36.8	69	83.7	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2712	NM_031313	Reynolds	SEAP	7124	AGAUGAUGAGGUUCUUGGCgg	GCCAAGAACCUCAUCAUCU	-3.4	-2.1	0.8	2	4	3	-38.4	70.8	10.4	5	Ia	47.4	56.9	90.8	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2713	NM_031313	Reynolds	SEAP	7124	CUGUAGUCAUCUGGGUACUca	AGUACCCAGAUGACUACAG	-2.1	-2.1	0.9	-1	-2	3	-38.6	57	-2.6	4	II	47.4	42.7	1.8	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2714	NM_031313	Reynolds	SEAP	7124	GUAUAGGAGGACCGUGUAGgc	CUACACGGUCCUCCUAUAC	-2.1	-2.2	-0.7	0	1	3	-39.3	48.9	5.1	6	II	52.6	41.8	21.2	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2715	NM_031313	Reynolds	SEAP	7124	AUAGCCUGGACCGUUUCCGua	CGGAAACGGUCCAGGCUAU	-2.4	-1.1	-3.5	3	6	3	-41.1	61.7	-2.4	4	Ib	57.9	67.7	80.2	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2716	NM_031313	Reynolds	SEAP	7124	ACAUAGCCUGGACCGUUUCcg	GAAACGGUCCAGGCUAUGU	-2.4	-2.2	-1.2	1	2	3	-39.7	56.7	12.5	5	Ib	52.6	52.9	6	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2717	NM_031313	Reynolds	SEAP	7124	CAUGACGUGCGCUAUGAAGgu	CUUCAUAGCGCACGUCAUG	-2.1	-2.1	1.2	0	0	4	-37.8	56.9	-1.7	4	II	52.6	45.1	16.5	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2718	NM_031313	Reynolds	SEAP	7124	UAUAGGAGGACCGUGUAGGcc	CCUACACGGUCCUCCUAUA	-3.3	-1.3	-0.7	1	5	3	-40.4	64.7	-2.4	8	Ia	52.6	72	62.4	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2719	U47296	Reynolds	FireflyLuc	116160065	UAUCAUGUCUGCUCGAAGCgg	GCUUCGAGCAGACAUGAUA	-3.4	-1.3	-1.2	2	4	2	-38	79.1	7.8	6	Ia	47.4	73.2	97.7	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2720	U47296	Reynolds	FireflyLuc	116160065	UUUUAGAAUCCAUGAUAAUaa	AUUAUCAUGGAUUCUAAAA	-1.1	-0.9	2	-1	1	2	-28.3	81.8	-3.6	8	II	21.1	60.4	55.5	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2721	U47296	Reynolds	FireflyLuc	116160065	CAAAUAUCCGAGUGUAGUAaa	UACUACACUCGGAUAUUUG	-1.3	-2.1	1.4	0	-2	3	-33.4	68.6	-3.5	5	II	36.8	43.9	38.6	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2722	U47296	Reynolds	FireflyLuc	116160065	GGAUUGUUUACAUAACCGGac	CCGGUUAUGUAAACAAUCC	-3.3	-3.3	0.3	1	2	4	-33.9	67.5	-2.4	5	II	42.1	55.1	41.6	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2723	U47296	Reynolds	FireflyLuc	116160065	CGCUUCCGGAUUGUUUACAua	UGUAAACAAUCCGGAAGCG	-2.1	-2.4	0	0	-3	4	-36.3	61.8	-0.4	3	III	47.4	34.4	9.9	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2724	U47296	Reynolds	FireflyLuc	116160065	GGCGUUGGUCGCUUCCGGAuu	UCCGGAAGCGACCAACGCC	-2.4	-3.3	-2.3	0	-1	4	-44.8	39.5	-3.8	0	III	68.4	28.8	89.7	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2725	U47296	Reynolds	FireflyLuc	116160065	GUACUUAAUCAGAGACUUCag	GAAGUCUCUGAUUAAGUAC	-2.4	-2.2	0.8	0	1	1	-33.1	64.9	7.1	5	II	36.8	54.6	34.7	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2726	U47296	Reynolds	FireflyLuc	116160065	UUUGUAUUCAGCCCAUAUCgu	GAUAUGGGCUGAAUACAAA	-2.4	-0.9	1.3	2	3	4	-34	89.8	7.5	8	Ia	36.8	76.9	91.9	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2727	U47296	Reynolds	FireflyLuc	116160065	UACUUAAUCAGAGACUUCAgg	UGAAGUCUCUGAUUAAGUA	-2.1	-1.3	0.8	1	0	1	-33	84.3	-3.8	9	II	31.6	67.5	91.9	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2728	NM_020548	Reynolds	DBI	1622	GCUCAUUCCAGGCAUCCCAcu	UGGGAUGCCUGGAAUGAGC	-2.1	-3.4	-0.3	3	-1	3	-42.9	50.6	1.4	3	II	57.9	39.4	4.9	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2729	NM_020548	Reynolds	DBI	1622	GUAAGCUUUCAUGGCAUCUuc	AGAUGCCAUGAAAGCUUAC	-2.1	-2.2	0.3	0	0	3	-35.9	67.9	1.4	5	II	42.1	49.9	-9.1	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2730	NM_020548	Reynolds	DBI	1622	AACAAGGCAUUGUCUCAGUuu	ACUGAGACAAUGCCUUGUU	-2.2	-0.9	-1	1	1	3	-36.6	64	-1.3	5	II	42.1	53.3	6	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2731	NM_020548	Reynolds	DBI	1622	GGAAAGUCAGUAAUCGUUUua	AAACGAUUACUGACUUUCC	-0.9	-3.3	1.9	1	-1	2	-32.7	61.9	-1.5	5	II	36.8	46.5	-18.6	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2732	NM_020548	Reynolds	DBI	1622	ACUCAAGGAAAGUCAGUAAuc	UUACUGACUUUCCUUGAGU	-0.9	-2.2	-0.7	2	-1	2	-34.6	61.7	1.3	7	II	36.8	39.7	-8.4	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2733	NM_020548	Reynolds	DBI	1622	UAAGCUUUCAUGGCAUCUUcc	AAGAUGCCAUGAAAGCUUA	-0.9	-1.3	0.3	2	2	3	-34.6	78.8	-4	7	II	36.8	70.8	50.7	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2734	NM_020548	Reynolds	DBI	1622	UUGUUGAUGUAAGCUUUCAug	UGAAAGCUUACAUCAACAA	-2.1	-0.9	1.3	1	0	2	-32.1	82.1	-1.5	8	II	31.6	64.7	33.7	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2735	NM_020548	Reynolds	DBI	1622	UCUUUAGCUCUUCUACUUUgu	AAAGUAGAAGAGCUAAAGA	-0.9	-2.4	-0.2	0	1	2	-32.5	83.9	3.8	8	II	31.6	58.9	71.8	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2736	NM_020548	Reynolds	DBI	1622	UAUUUUUUCUUUAGCUCUUcu	AAGAGCUAAAGAAAAAAUA	-0.9	-1.3	5.2	1	2	2	-27.5	100.6	-3.5	8	II	21.1	70.9	68	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2737	X75932	Reynolds	PLK	5347	GCACUUGGCAAAGCCGCCCuu	GGGCGGCUUUGCCAAGUGC	-3.3	-3.4	-4.2	2	2	7	-44.6	38.9	9.7	2	II	68.4	50.3	30.6	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2738	X75932	Reynolds	PLK	5347	GGAUAUUUCCAUGGACAUCuu	GAUGUCCAUGGAAAUAUCC	-2.4	-3.3	-1.3	1	0	2	-35.5	65.8	15.4	3	II	42.1	46.1	43.9	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2739	X75932	Reynolds	PLK	5347	CACAUCCACCUCGAAACUGug	CAGUUUCGAGGUGGAUGUG	-2.1	-2.1	1.1	0	0	2	-38.3	50	-4.4	3	II	52.6	47.6	52.6	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2740	X75932	Reynolds	PLK	5347	GGAAUACUGUAUUCAUUCUuc	AGAAUGAAUACAGUAUUCC	-2.1	-3.3	-0.8	1	-1	2	-31.9	77.9	1.4	4	II	31.6	40	58	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2741	X75932	Reynolds	PLK	5347	AUGAGGCGUGUUGAGUCAUug	AUGACUCAACACGCCUCAU	-1.1	-1.1	1.3	1	1	4	-38.6	50.4	-1	4	II	47.4	48	58.4	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2742	X75932	Reynolds	PLK	5347	UCAUGUAAUUGCGGAAAUAuu	UAUUUCCGCAAUUACAUGA	-1.3	-2.4	1.7	-1	-1	4	-31.9	63	-6.1	6	II	31.6	51.2	57.1	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2743	X75932	Reynolds	PLK	5347	AGAGACUUAGGCACAAUCUug	AGAUUGUGCCUAAGUCUCU	-2.1	-2.1	-1.6	2	1	3	-37.2	65.5	-6.2	5	II	42.1	58.2	68.5	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2744	X75932	Reynolds	PLK	5347	UUCACCUCCAGAUCUUCAUuc	AUGAAGAUCUGGAGGUGAA	-1.1	-0.9	0.4	2	1	2	-37.4	86.7	-4	7	II	42.1	62.8	55	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2745	X75932	Reynolds	PLK	5347	UUAGGCAAGAAGUCUCAAAag	UUUGAGACUUCUUGCCUAA	-0.9	-0.9	-0.3	1	0	3	-34.5	72.4	-1.5	7	II	36.8	60.5	82.2	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2746	X75932	Reynolds	PLK	5347	UAUUUAAGGAGGGUGAUCUuc	AGAUCACCCUCCUUAAAUA	-2.1	-1.3	1.7	1	3	3	-35.2	85.2	-1.6	10	II	36.8	70.6	72.5	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2747	NM_002046	Reynolds	GAPDH	2597	CCCUUUUGGCUCCCCCCUGca	CAGGGGGGAGCCAAAAGGG	-2.1	-3.3	-2.3	1	-1	6	-45.4	45.5	-2	1	II	68.4	43.8	-24.4	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2748	NM_002046	Reynolds	GAPDH	2597	AGGGGGCAGAGAUGAUGACcc	GUCAUCAUCUCUGCCCCCU	-2.2	-2.1	2.7	1	2	6	-43.2	37.5	7.4	2	II	57.9	41.5	69.8	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2749	NM_002046	Reynolds	GAPDH	2597	GAACAUGGGGGCAUCAGCAga	UGCUGAUGCCCCCAUGUUC	-2.1	-2.4	-0.6	2	1	6	-42.7	42.1	-3.7	3	II	57.9	43.2	12.7	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2750	NM_002046	Reynolds	GAPDH	2597	UCAUGGUUCACACCCAUGAcg	UCAUGGGUGUGAACCAUGA	-2.4	-2.4	-7	2	0	3	-39.4	67	-3.7	7	II	47.4	61.6	60.5	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2751	NM_002046	Reynolds	GAPDH	2597	UGAGGCUGUUGUCAUACUUcu	AAGUAUGACAACAGCCUCA	-0.9	-2.1	0.8	1	1	3	-37	67.8	1.5	5	II	42.1	57.6	94.2	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2752	NM_002046	Reynolds	GAPDH	2597	GGAGGCAUUGCUGAUGAUCuu	GAUCAUCAGCAAUGCCUCC	-2.4	-3.3	0.4	0	0	3	-39.8	48.2	8.1	2	II	52.6	44.6	70.8	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2753	NM_002046	Reynolds	GAPDH	2597	GCUAAGCAGUUGGUGGUGCag	GCACCACCAACUGCUUAGC	-3.4	-3.4	-1.3	1	2	2	-41.2	43.7	12.4	2	II	57.9	38.9	38.6	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2754	NM_002046	Reynolds	GAPDH	2597	GGAUGACCUUGGCCAGGGGug	CCCCUGGCCAAGGUCAUCC	-3.3	-3.3	-3.6	0	2	4	-46	33.4	2.4	0	II	68.4	30.5	-2.5	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2755	NM_002046	Reynolds	GAPDH	2597	CACGAUACCAAAGUUGUCAug	UGACAACUUUGGUAUCGUG	-2.1	-2.1	1.1	0	-2	2	-34.9	66.2	1.6	5	II	42.1	49.9	43	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2756	NM_002046	Reynolds	GAPDH	2597	ACUGUGGUCAUGAGUCCUUcc	AAGGACUCAUGACCACAGU	-0.9	-2.2	-0.7	1	1	2	-39.3	51.3	-6.6	6	II	47.4	50.3	-17.4	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2757	NM_002046	Reynolds	GAPDH	2597	UGAUGACCCUUUUGGCUCCcc	GGAGCCAAAAGGGUCAUCA	-3.3	-2.1	-1.5	0	3	3	-40.3	64.3	10.4	5	Ib	52.6	61.6	88.7	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2758	NM_002046	Reynolds	GAPDH	2597	GAGAUGAUGACCCUUUUGGcu	CCAAAAGGGUCAUCAUCUC	-3.3	-2.4	-0.6	1	2	3	-37.1	72.4	0	6	II	47.4	55.9	93.9	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2759	NM_002046	Reynolds	GAPDH	2597	UUCACACCCAUGACGAACAug	UGUUCGUCAUGGGUGUGAA	-2.1	-0.9	-1.5	1	0	3	-38.4	66.6	-6.3	5	II	47.4	62	80.3	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2760	NM_002046	Reynolds	GAPDH	2597	UACUUCUCAUGGUUCACACcc	GUGUGAACCAUGAGAAGUA	-2.2	-1.3	0.9	1	4	2	-36.1	92	9.7	7	Ia	42.1	68.6	92.7	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2761	NM_002046	Reynolds	GAPDH	2597	UUGUCAUACUUCUCAUGGUuc	ACCAUGAGAAGUAUGACAA	-2.2	-0.9	-0.3	2	2	2	-35	80.6	-6.3	6	II	36.8	63.6	92.5	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2762	NM_002046	Reynolds	GAPDH	2597	UGUUGUCAUACUUCUCAUGgu	CAUGAGAAGUAUGACAACA	-2.1	-2.1	0	0	2	1	-33.8	86.5	0.7	6	Ib	36.8	65.5	92.4	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2763	NM_002046	Reynolds	GAPDH	2597	CUUGAGGCUGUUGUCAUACuu	GUAUGACAACAGCCUCAAG	-2.2	-2.1	0.3	-1	1	3	-37	60.9	13.5	5	II	47.4	55.1	77.6	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2764	NM_002046	Reynolds	GAPDH	2597	AUCUUGAGGCUGUUGUCAUac	AUGACAACAGCCUCAAGAU	-1.1	-1.1	0.3	2	2	3	-37	71.3	-1.6	6	II	42.1	52.3	58.3	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2765	NM_002046	Reynolds	GAPDH	2597	UGAUCUUGAGGCUGUUGUCau	GACAACAGCCUCAAGAUCA	-2.4	-2.1	1.3	0	3	3	-38.3	76.1	5.1	6	Ia	47.4	62.6	94.2	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2766	NM_002046	Reynolds	GAPDH	2597	UCAUGGAUGACCUUGGCCAgg	UGGCCAAGGUCAUCCAUGA	-2.1	-2.4	-3.5	1	2	4	-41.7	63	-6.1	6	II	52.6	61.3	91.5	Luciferase reporter assay	HEK293	100nM	24h	Rational siRNA design for RNA interference.	14758366	2004	Nature Biotechnology	2004/2/1
MC2767	U92436	Vickers	MMAC1	5728	GCGAGAGGCGGACGGGACCgc	GGUCCCGUCCGCCUCUCGC	-3.3	-3.4	-1.2	0	0	5	-48.7	19.1	9.8	0	II	78.9	34.4	0	Luciferase reporter assay	T24	200nM	16h	Efficient reduction of target RNAs by small interfering RNA and RNase H-dependent antisense agents.	12500975	2003	Journal of Biological Chemistry	2003/2/1
MC2768	U92436	Vickers	MMAC1	5728	CCGGGCGCCUCGGAAGACCga	GGUCUUCCGAGGCGCCCGG	-3.3	-3.3	-2.7	0	-1	9	-48.3	18.1	3.1	-1	II	78.9	38.5	0	Luciferase reporter assay	T24	200nM	16h	Efficient reduction of target RNAs by small interfering RNA and RNase H-dependent antisense agents.	12500975	2003	Journal of Biological Chemistry	2003/2/1
MC2769	U92436	Vickers	MMAC1	5728	AUGGCUGCAGCUUCCGAGAgg	UCUCGGAAGCUGCAGCCAU	-2.4	-1.1	-0.5	1	0	3	-43.1	56.6	-3.1	3	II	57.9	50.7	40	Luciferase reporter assay	T24	200nM	16h	Efficient reduction of target RNAs by small interfering RNA and RNase H-dependent antisense agents.	12500975	2003	Journal of Biological Chemistry	2003/2/1
MC2770	U92436	Vickers	MMAC1	5728	CCCCGCGGCUGCUCACAGGcg	CCUGUGAGCAGCCGCGGGG	-3.3	-3.3	-8.1	1	-1	9	-48.7	26.2	-4.4	-1	II	78.9	32.8	25	Luciferase reporter assay	T24	200nM	16h	Efficient reduction of target RNAs by small interfering RNA and RNase H-dependent antisense agents.	12500975	2003	Journal of Biological Chemistry	2003/2/1
MC2771	U92436	Vickers	MMAC1	5728	UCAGGAGAAGCCGAGGAAGag	CUUCCUCGGCUUCUCCUGA	-2.1	-2.4	-0.8	0	2	4	-42.1	36.4	-4.7	4	II	57.9	53.5	62	Luciferase reporter assay	T24	200nM	16h	Efficient reduction of target RNAs by small interfering RNA and RNase H-dependent antisense agents.	12500975	2003	Journal of Biological Chemistry	2003/2/1
MC2772	U92436	Vickers	MMAC1	5728	CGGGAGGUGCCGCCGCCGCcg	GCGGCGGCGGCACCUCCCG	-3.4	-2.4	-1.2	0	0	11	-51.8	14.6	8.2	0	II	89.5	37.5	20	Luciferase reporter assay	T24	200nM	16h	Efficient reduction of target RNAs by small interfering RNA and RNase H-dependent antisense agents.	12500975	2003	Journal of Biological Chemistry	2003/2/1
MC2773	U92436	Vickers	MMAC1	5728	CCCGGGUCCCUGGAUGUGCcg	GCACAUCCAGGGACCCGGG	-3.4	-3.3	-0.6	1	-1	6	-47.6	29.1	5.4	1	II	73.7	41.8	32	Luciferase reporter assay	T24	200nM	16h	Efficient reduction of target RNAs by small interfering RNA and RNase H-dependent antisense agents.	12500975	2003	Journal of Biological Chemistry	2003/2/1
MC2774	U92436	Vickers	MMAC1	5728	UCCUCCGAACGGCUGCCUCcg	GAGGCAGCCGUUCGGAGGA	-2.4	-2.4	-1	0	3	4	-45.9	55.2	12.1	3	II	68.4	53.9	58	Luciferase reporter assay	T24	200nM	16h	Efficient reduction of target RNAs by small interfering RNA and RNase H-dependent antisense agents.	12500975	2003	Journal of Biological Chemistry	2003/2/1
MC2775	U92436	Vickers	MMAC1	5728	UUCUCCUCAGCAGCCAGAGgc	CUCUGGCUGCUGAGGAGAA	-2.1	-0.9	-2.2	1	3	3	-42.8	63.1	-2.4	4	Ib	57.9	61.9	52	Luciferase reporter assay	T24	200nM	16h	Efficient reduction of target RNAs by small interfering RNA and RNase H-dependent antisense agents.	12500975	2003	Journal of Biological Chemistry	2003/2/1
MC2776	U92436	Vickers	MMAC1	5728	CCGCUUGGCUCUGGACCGCag	GCGGUCCAGAGCCAAGCGG	-3.4	-3.3	-2.4	0	0	4	-46.6	26.1	6.1	0	II	73.7	36.5	31	Luciferase reporter assay	T24	200nM	16h	Efficient reduction of target RNAs by small interfering RNA and RNase H-dependent antisense agents.	12500975	2003	Journal of Biological Chemistry	2003/2/1
MC2777	U92436	Vickers	MMAC1	5728	UUCUUCUGCAGGAUGGAAAug	UUUCCAUCCUGCAGAAGAA	-0.9	-0.9	0.7	2	0	2	-36.9	82	-4	8	II	42.1	58.8	27	Luciferase reporter assay	T24	200nM	16h	Efficient reduction of target RNAs by small interfering RNA and RNase H-dependent antisense agents.	12500975	2003	Journal of Biological Chemistry	2003/2/1
MC2778	U92436	Vickers	MMAC1	5728	UGGAUAAAUAUAGGUCAAGuc	CUUGACCUAUAUUUAUCCA	-2.1	-2.1	3	-1	1	2	-31.9	67.6	0	7	Ia	31.6	62.5	48	Luciferase reporter assay	T24	200nM	16h	Efficient reduction of target RNAs by small interfering RNA and RNase H-dependent antisense agents.	12500975	2003	Journal of Biological Chemistry	2003/2/1
MC2779	U92436	Vickers	MMAC1	5728	AUCAAUAUUGUUCCUGUAUac	AUACAGGAACAAUAUUGAU	-1.1	-1.1	0.4	1	0	2	-30.6	88.8	4.2	7	II	26.3	59.2	49	Luciferase reporter assay	T24	200nM	16h	Efficient reduction of target RNAs by small interfering RNA and RNase H-dependent antisense agents.	12500975	2003	Journal of Biological Chemistry	2003/2/1
MC2780	U92436	Vickers	MMAC1	5728	AUUAAAUUUGGCGGUGUCAua	UGACACCGCCAAAUUUAAU	-2.1	-1.1	2	1	1	5	-33.5	70.1	-3.4	8	II	36.8	54.9	65	Luciferase reporter assay	T24	200nM	16h	Efficient reduction of target RNAs by small interfering RNA and RNase H-dependent antisense agents.	12500975	2003	Journal of Biological Chemistry	2003/2/1
MC2781	U92436	Vickers	MMAC1	5728	UCAAGAUCUUCACAAAAGGgu	CCUUUUGUGAAGAUCUUGA	-3.3	-2.4	0.5	1	3	2	-33.3	66.5	0.1	6	Ia	36.8	67.5	73	Luciferase reporter assay	T24	200nM	16h	Efficient reduction of target RNAs by small interfering RNA and RNase H-dependent antisense agents.	12500975	2003	Journal of Biological Chemistry	2003/2/1
MC2782	U92436	Vickers	MMAC1	5728	CAUUACACCAGUUCGUCCCuu	GGGACGAACUGGUGUAAUG	-3.3	-2.1	0.7	0	2	3	-38.5	78.6	11.1	6	II	52.6	61.8	75	Luciferase reporter assay	T24	200nM	16h	Efficient reduction of target RNAs by small interfering RNA and RNase H-dependent antisense agents.	12500975	2003	Journal of Biological Chemistry	2003/2/1
MC2783	U92436	Vickers	MMAC1	5728	UUGUCUCUGGUCCUUACUUcc	AAGUAAGGACCAGAGACAA	-0.9	-0.9	1.8	1	2	2	-37	79.6	-1.6	5	II	42.1	63.4	75	Luciferase reporter assay	T24	200nM	16h	Efficient reduction of target RNAs by small interfering RNA and RNase H-dependent antisense agents.	12500975	2003	Journal of Biological Chemistry	2003/2/1
MC2784	U92436	Vickers	MMAC1	5728	CACAUAGCGCCUCUGACUGgg	CAGUCAGAGGCGCUAUGUG	-2.1	-2.1	-0.5	0	1	5	-40.9	57.2	3.4	3	II	57.9	47.6	73	Luciferase reporter assay	T24	200nM	16h	Efficient reduction of target RNAs by small interfering RNA and RNase H-dependent antisense agents.	12500975	2003	Journal of Biological Chemistry	2003/2/1
MC2785	U92436	Vickers	MMAC1	5728	GGAAUAUAUCUUCACCUUUag	AAAGGUGAAGAUAUAUUCC	-0.9	-3.3	0.2	1	-2	2	-31.8	71.5	1.5	5	II	31.6	45.6	9	Luciferase reporter assay	T24	200nM	16h	Efficient reduction of target RNAs by small interfering RNA and RNase H-dependent antisense agents.	12500975	2003	Journal of Biological Chemistry	2003/2/1
MC2786	U92436	Vickers	MMAC1	5728	UGGAAGAACUCUACUUUGAua	UCAAAGUAGAGUUCUUCCA	-2.4	-2.1	1.2	1	-1	2	-34.8	71	-3	7	II	36.8	56.2	30	Luciferase reporter assay	T24	200nM	16h	Efficient reduction of target RNAs by small interfering RNA and RNase H-dependent antisense agents.	12500975	2003	Journal of Biological Chemistry	2003/2/1
MC2787	U92436	Vickers	MMAC1	5728	AUGAAGAAUGUAUUUACCCaa	GGGUAAAUACAUUCUUCAU	-3.3	-1.1	-0.1	1	5	3	-31.6	80	12.4	6	Ia	31.6	78.2	70	Luciferase reporter assay	T24	200nM	16h	Efficient reduction of target RNAs by small interfering RNA and RNase H-dependent antisense agents.	12500975	2003	Journal of Biological Chemistry	2003/2/1
MC2788	U92436	Vickers	MMAC1	5728	CGGUUGGCUUUGUCUUUAUuu	AUAAAGACAAAGCCAACCG	-1.1	-2.4		-1	-4	3	-34.5	64.5	-6	4	III	42.1	34.8	0	Luciferase reporter assay	T24	200nM	16h	Efficient reduction of target RNAs by small interfering RNA and RNase H-dependent antisense agents.	12500975	2003	Journal of Biological Chemistry	2003/2/1
MC2789	U92436	Vickers	MMAC1	5728	CUGCUAGCCUCUGGAUUUGac	CAAAUCCAGAGGCUAGCAG	-2.1	-2.1	1.9	0	-1	3	-39.2	48	-1.3	4	II	52.6	41.4	44	Luciferase reporter assay	T24	200nM	16h	Efficient reduction of target RNAs by small interfering RNA and RNase H-dependent antisense agents.	12500975	2003	Journal of Biological Chemistry	2003/2/1
MC2790	U92436	Vickers	MMAC1	5728	CUCUGGAUCAGAGUCAGUGgu	CACUGACUCUGAUCCAGAG	-2.1	-2.1	-3.5	0	1	2	-39.7	59.1	0.3	3	II	52.6	54.2	15	Luciferase reporter assay	T24	200nM	16h	Efficient reduction of target RNAs by small interfering RNA and RNase H-dependent antisense agents.	12500975	2003	Journal of Biological Chemistry	2003/2/1
MC2791	U92436	Vickers	MMAC1	5728	UUAUUUUCAUGGUGUUUUAuc	UAAAACACCAUGAAAAUAA	-1.3	-0.9	1.1	0	0	2	-27.5	99.9	-3.8	9	II	21.1	62.7	58	Luciferase reporter assay	T24	200nM	16h	Efficient reduction of target RNAs by small interfering RNA and RNase H-dependent antisense agents.	12500975	2003	Journal of Biological Chemistry	2003/2/1
MC2792	U92436	Vickers	MMAC1	5728	UUGUUCCUAUAACUGGUAAuc	UUACCAGUUAUAGGAACAA	-0.9	-0.9	-0.5	0	0	2	-32.6	87.9	3.3	7	II	31.6	52.9	40	Luciferase reporter assay	T24	200nM	16h	Efficient reduction of target RNAs by small interfering RNA and RNase H-dependent antisense agents.	12500975	2003	Journal of Biological Chemistry	2003/2/1
MC2793	U92436	Vickers	MMAC1	5728	AGUGUCAAAACCCUGUGGAug	UCCACAGGGUUUUGACACU	-2.4	-2.1	0.2	1	2	3	-38.8	64.2	-3.7	6	II	47.4	48.3	45	Luciferase reporter assay	T24	200nM	16h	Efficient reduction of target RNAs by small interfering RNA and RNase H-dependent antisense agents.	12500975	2003	Journal of Biological Chemistry	2003/2/1
MC2794	U92436	Vickers	MMAC1	5728	AACUGGAAUAAAACGGGAAag	UUCCCGUUUUAUUCCAGUU	-0.9	-0.9	3.8	1	0	4	-33.5	63	-4	6	II	36.8	49.4	38	Luciferase reporter assay	T24	200nM	16h	Efficient reduction of target RNAs by small interfering RNA and RNase H-dependent antisense agents.	12500975	2003	Journal of Biological Chemistry	2003/2/1
MC2795	U92436	Vickers	MMAC1	5728	CACUUCAGUUGGUGACAGAac	UCUGUCACCAACUGAAGUG	-2.4	-2.1	0.2	-2	-3	2	-37.9	56.6	-5.8	4	II	47.4	33.9	25	Luciferase reporter assay	T24	200nM	16h	Efficient reduction of target RNAs by small interfering RNA and RNase H-dependent antisense agents.	12500975	2003	Journal of Biological Chemistry	2003/2/1
MC2796	U92436	Vickers	MMAC1	5728	GUAGCAAAACCUUUCGGAAac	UUCCGAAAGGUUUUGCUAC	-0.9	-2.2	-3.6	0	0	3	-34.6	61.4	-0.8	2	II	42.1	35.9	32	Luciferase reporter assay	T24	200nM	16h	Efficient reduction of target RNAs by small interfering RNA and RNase H-dependent antisense agents.	12500975	2003	Journal of Biological Chemistry	2003/2/1
MC2797	U92436	Vickers	MMAC1	5728	AAAUUAUUUCCUUUCUGAGca	CUCAGAAAGGAAAUAAUUU	-2.1	-0.9	1.2	2	5	2	-28.7	98.8	3	7	Ia	26.3	66	30	Luciferase reporter assay	T24	200nM	16h	Efficient reduction of target RNAs by small interfering RNA and RNase H-dependent antisense agents.	12500975	2003	Journal of Biological Chemistry	2003/2/1
MC2798	U92436	Vickers	MMAC1	5728	GUAAAUAGCUGGAGAUGGUau	ACCAUCUCCAGCUAUUUAC	-2.2	-2.2	4.3	0	1	2	-36.3	54.6	-3.9	5	II	42.1	42.9	6	Luciferase reporter assay	T24	200nM	16h	Efficient reduction of target RNAs by small interfering RNA and RNase H-dependent antisense agents.	12500975	2003	Journal of Biological Chemistry	2003/2/1
MC2799	U92436	Vickers	MMAC1	5728	CCAGAUUAAUAACUGUAGCau	GCUACAGUUAUUAAUCUGG	-3.4	-3.3	-1.9	0	1	2	-32.8	70.6	15.1	2	II	36.8	53.3	37	Luciferase reporter assay	T24	200nM	16h	Efficient reduction of target RNAs by small interfering RNA and RNase H-dependent antisense agents.	12500975	2003	Journal of Biological Chemistry	2003/2/1
MC2800	U92436	Vickers	MMAC1	5728	ACCCCAAUACAGAUUCACUuc	AGUGAAUCUGUAUUGGGGU	-2.1	-2.2	0.3	2	1	4	-37.1	64.9	-1.9	3	II	42.1	49.2	39	Luciferase reporter assay	T24	200nM	16h	Efficient reduction of target RNAs by small interfering RNA and RNase H-dependent antisense agents.	12500975	2003	Journal of Biological Chemistry	2003/2/1
MC2801	U92436	Vickers	MMAC1	5728	CAUUGUUGCUGUGUUUCUUac	AAGAAACACAGCAACAAUG	-0.9	-2.1	2.2	1	0	2	-32.7	80.4	-0.6	4	II	36.8	46.5	30	Luciferase reporter assay	T24	200nM	16h	Efficient reduction of target RNAs by small interfering RNA and RNase H-dependent antisense agents.	12500975	2003	Journal of Biological Chemistry	2003/2/1
MC2802	U92436	Vickers	MMAC1	5728	AUGUUUCAAGCCCAUUCUUug	AAGAAUGGGCUUGAAACAU	-0.9	-1.1	0.9	1	1	4	-34.2	73.1	-6.3	5	II	36.8	54.2	40	Luciferase reporter assay	T24	200nM	16h	Efficient reduction of target RNAs by small interfering RNA and RNase H-dependent antisense agents.	12500975	2003	Journal of Biological Chemistry	2003/2/1
MC2803	J03132	Vickers	ICAM-1	3383	GAGGAGCUCAGCGUCGACUgg	AGUCGACGCUGAGCUCCUC	-2.1	-2.4	0.7	1	0	3	-43.9	43.2	-1.3	2	III	63.2	42	0	Luciferase reporter assay	T24	200nM	16h	Efficient reduction of target RNAs by small interfering RNA and RNase H-dependent antisense agents.	12500975	2003	Journal of Biological Chemistry	2003/2/1
MC2804	J03132	Vickers	ICAM-1	3383	GCUGAGGUUGCAACUCUGAgu	UCAGAGUUGCAACCUCAGC	-2.4	-3.4	-1.5	0	-2	2	-40.3	39.4	-6	3	III	52.6	33.4	1	Luciferase reporter assay	T24	200nM	16h	Efficient reduction of target RNAs by small interfering RNA and RNase H-dependent antisense agents.	12500975	2003	Journal of Biological Chemistry	2003/2/1
MC2805	J03132	Vickers	ICAM-1	3383	CAGGCAGGAGCAACUCCUUuu	AAGGAGUUGCUCCUGCCUG	-0.9	-2.1	-4.7	-1	-2	3	-42.3	35.6	-10.9	0	III	57.9	38	-15	Luciferase reporter assay	T24	200nM	16h	Efficient reduction of target RNAs by small interfering RNA and RNase H-dependent antisense agents.	12500975	2003	Journal of Biological Chemistry	2003/2/1
MC2806	J03132	Vickers	ICAM-1	3383	UGAAUAGCACAUUGGUUGGcu	CCAACCAAUGUGCUAUUCA	-3.3	-2.1	2.1	-1	3	2	-35.6	77.3	5.3	8	Ia	42.1	63.4	7	Luciferase reporter assay	T24	200nM	16h	Efficient reduction of target RNAs by small interfering RNA and RNase H-dependent antisense agents.	12500975	2003	Journal of Biological Chemistry	2003/2/1
MC2807	J03132	Vickers	ICAM-1	3383	CCCACUGGCUGCCAAGAGGgg	CCUCUUGGCAGCCAGUGGG	-3.3	-3.3	-0.5	0	-1	3	-45.6	40.1	-2	1	II	68.4	38.7	18	Luciferase reporter assay	T24	200nM	16h	Efficient reduction of target RNAs by small interfering RNA and RNase H-dependent antisense agents.	12500975	2003	Journal of Biological Chemistry	2003/2/1
MC2808	J03132	Vickers	ICAM-1	3383	CUCUCCUCACCAGCACCGUgg	ACGGUGCUGGUGAGGAGAG	-2.2	-2.1	1.3	0	-1	3	-44.2	45.8	-8.3	2	III	63.2	39.3	-20	Luciferase reporter assay	T24	200nM	16h	Efficient reduction of target RNAs by small interfering RNA and RNase H-dependent antisense agents.	12500975	2003	Journal of Biological Chemistry	2003/2/1
MC2809	J03132	Vickers	ICAM-1	3383	AAGGUCUGGAGCUGGUAGGgg	CCUACCAGCUCCAGACCUU	-3.3	-0.9	2.6	2	3	2	-42.7	60.2	-2.4	5	Ib	57.9	59.2	45	Luciferase reporter assay	T24	200nM	16h	Efficient reduction of target RNAs by small interfering RNA and RNase H-dependent antisense agents.	12500975	2003	Journal of Biological Chemistry	2003/2/1
MC2810	J03132	Vickers	ICAM-1	3383	CGUGUCCACCUCUAGGACCcg	GGUCCUAGAGGUGGACACG	-3.3	-2.4	-5.7	0	0	2	-43.4	49.1	3.1	0	II	63.2	47.8	10	Luciferase reporter assay	T24	200nM	16h	Efficient reduction of target RNAs by small interfering RNA and RNase H-dependent antisense agents.	12500975	2003	Journal of Biological Chemistry	2003/2/1
MC2811	J03132	Vickers	ICAM-1	3383	CAGUGCCAGGUGGACCUGGgc	CCAGGUCCACCUGGCACUG	-3.3	-2.1	-7.5	0	0	3	-45.7	34	-2	1	II	68.4	44.4	21	Luciferase reporter assay	T24	200nM	16h	Efficient reduction of target RNAs by small interfering RNA and RNase H-dependent antisense agents.	12500975	2003	Journal of Biological Chemistry	2003/2/1
MC2812	J03132	Vickers	ICAM-1	3383	CAGUAUUACUGCACACGUCag	GACGUGUGCAGUAAUACUG	-2.4	-2.1	-2.1	1	0	2	-36.4	63.7	3.2	3	II	47.4	53.8	30	Luciferase reporter assay	T24	200nM	16h	Efficient reduction of target RNAs by small interfering RNA and RNase H-dependent antisense agents.	12500975	2003	Journal of Biological Chemistry	2003/2/1
MC2813	J03132	Vickers	ICAM-1	3383	CUCUGGCUUCGUCAGAAUCac	GAUUCUGACGAAGCCAGAG	-2.4	-2.1	-2.7	-1	-1	3	-38.8	60.7	10.8	1	II	52.6	47.2	-10	Luciferase reporter assay	T24	200nM	16h	Efficient reduction of target RNAs by small interfering RNA and RNase H-dependent antisense agents.	12500975	2003	Journal of Biological Chemistry	2003/2/1
MC2814	J03132	Vickers	ICAM-1	3383	GUGGCCUUCAGCAGGAGCUgg	AGCUCCUGCUGAAGGCCAC	-2.1	-2.2	-2.1	1	0	4	-44.8	49.1	-8.9	1	III	63.2	44.6	10	Luciferase reporter assay	T24	200nM	16h	Efficient reduction of target RNAs by small interfering RNA and RNase H-dependent antisense agents.	12500975	2003	Journal of Biological Chemistry	2003/2/1
MC2815	J03132	Vickers	ICAM-1	3383	AUACAGGACACGAAGCUCCcg	GGAGCUUCGUGUCCUGUAU	-3.3	-1.1	-1.5	3	4	2	-40	54.4	5.2	7	Ib	52.6	72.5	58	Luciferase reporter assay	T24	200nM	16h	Efficient reduction of target RNAs by small interfering RNA and RNase H-dependent antisense agents.	12500975	2003	Journal of Biological Chemistry	2003/2/1
MC2816	J03132	Vickers	ICAM-1	3383	AUCCUUUAGACACUUGAGCuc	GCUCAAGUGUCUAAAGGAU	-3.4	-1.1	0.3	4	4	2	-36	78.5	9.8	6	Ia	42.1	69	40	Luciferase reporter assay	T24	200nM	16h	Efficient reduction of target RNAs by small interfering RNA and RNase H-dependent antisense agents.	12500975	2003	Journal of Biological Chemistry	2003/2/1
MC2817	J03132	Vickers	ICAM-1	3383	CUCCUGGCCCGACAGAGGUag	ACCUCUGUCGGGCCAGGAG	-2.2	-2.1	-1.7	1	-1	6	-46.5	35.7	-3.6	1	III	68.4	39.7	5	Luciferase reporter assay	T24	200nM	16h	Efficient reduction of target RNAs by small interfering RNA and RNase H-dependent antisense agents.	12500975	2003	Journal of Biological Chemistry	2003/2/1
MC2818	J03132	Vickers	ICAM-1	3383	CUACCACAGUGAUGAUGACaa	GUCAUCAUCACUGUGGUAG	-2.2	-2.1	-1.3	0	1	2	-37.5	48.3	5.4	1	II	47.4	36.4	35	Luciferase reporter assay	T24	200nM	16h	Efficient reduction of target RNAs by small interfering RNA and RNase H-dependent antisense agents.	12500975	2003	Journal of Biological Chemistry	2003/2/1
MC2819	J03132	Vickers	ICAM-1	3383	UGUGUGUUCGGUUUCAUGGgg	CCAUGAAACCGAACACACA	-3.3	-2.1	2.1	2	4	3	-36.9	87.5	5.4	7	Ib	47.4	73.5	59	Luciferase reporter assay	T24	200nM	16h	Efficient reduction of target RNAs by small interfering RNA and RNase H-dependent antisense agents.	12500975	2003	Journal of Biological Chemistry	2003/2/1
MC2820	J03132	Vickers	ICAM-1	3383	GAGGCGUGGCUUGUGUGUUcg	AACACACAAGCCACGCCUC	-0.9	-2.4	1.3	2	0	4	-41.4	46.7	1.4	1	III	57.9	36.9	1	Luciferase reporter assay	T24	200nM	16h	Efficient reduction of target RNAs by small interfering RNA and RNase H-dependent antisense agents.	12500975	2003	Journal of Biological Chemistry	2003/2/1
MC2821	J03132	Vickers	ICAM-1	3383	CUGUCCCGGGAUAGGUUCAgg	UGAACCUAUCCCGGGACAG	-2.1	-2.1	-1.7	-1	-3	6	-42.2	50.9	-3	1	III	57.9	34.5	20	Luciferase reporter assay	T24	200nM	16h	Efficient reduction of target RNAs by small interfering RNA and RNase H-dependent antisense agents.	12500975	2003	Journal of Biological Chemistry	2003/2/1
MC2822	J03132	Vickers	ICAM-1	3383	GAGGAAGAGGCCCUGUCCCgg	GGGACAGGGCCUCUUCCUC	-3.3	-2.4	-3.6	1	3	5	-46.4	37	10.1	1	II	68.4	47.3	52	Luciferase reporter assay	T24	200nM	16h	Efficient reduction of target RNAs by small interfering RNA and RNase H-dependent antisense agents.	12500975	2003	Journal of Biological Chemistry	2003/2/1
MC2823	J03132	Vickers	ICAM-1	3383	CCACUCUGUUCAGUGUGGCac	GCCACACUGAACAGAGUGG	-3.4	-3.3	-3.5	1	2	3	-41.3	48.3	5.4	1	II	57.9	45.1	21	Luciferase reporter assay	T24	200nM	16h	Efficient reduction of target RNAs by small interfering RNA and RNase H-dependent antisense agents.	12500975	2003	Journal of Biological Chemistry	2003/2/1
MC2824	J03132	Vickers	ICAM-1	3383	CUGACUGAGGACAAUGCCCug	GGGCAUUGUCCUCAGUCAG	-3.3	-2.1	-4.1	0	1	4	-41.6	53.9	2.8	1	II	57.9	59.3	62	Luciferase reporter assay	T24	200nM	16h	Efficient reduction of target RNAs by small interfering RNA and RNase H-dependent antisense agents.	12500975	2003	Journal of Biological Chemistry	2003/2/1
MC2825	J03132	Vickers	ICAM-1	3383	AGGUGUGCAGGUACCAUGGcc	CCAUGGUACCUGCACACCU	-3.3	-2.1	-1.4	1	2	2	-42.5	59.1	0.4	3	II	57.9	57.3	75	Luciferase reporter assay	T24	200nM	16h	Efficient reduction of target RNAs by small interfering RNA and RNase H-dependent antisense agents.	12500975	2003	Journal of Biological Chemistry	2003/2/1
MC2826	J03132	Vickers	ICAM-1	3383	CUCUCAUCAGGCUAGACUUua	AAGUCUAGCCUGAUGAGAG	-0.9	-2.1	-0.9	0	-2	3	-38.6	66.7	-8.3	3	II	47.4	44.7	50	Luciferase reporter assay	T24	200nM	16h	Efficient reduction of target RNAs by small interfering RNA and RNase H-dependent antisense agents.	12500975	2003	Journal of Biological Chemistry	2003/2/1
MC2827	J03132	Vickers	ICAM-1	3383	CAGUUGUAUGUCCUCAUGGug	CCAUGAGGACAUACAACUG	-3.3	-2.1	-0.3	0	1	2	-37.1	71	0.4	5	II	47.4	60.7	58	Luciferase reporter assay	T24	200nM	16h	Efficient reduction of target RNAs by small interfering RNA and RNase H-dependent antisense agents.	12500975	2003	Journal of Biological Chemistry	2003/2/1
MC2828	J03132	Vickers	ICAM-1	3383	GGCCUCAGCAUACCCAAUAgg	UAUUGGGUAUGCUGAGGCC	-1.3	-3.3	-0.8	2	-4	4	-40.8	47.3	-1.4	3	III	52.6	34	43	Luciferase reporter assay	T24	200nM	16h	Efficient reduction of target RNAs by small interfering RNA and RNase H-dependent antisense agents.	12500975	2003	Journal of Biological Chemistry	2003/2/1
MC2829	J03132	Vickers	ICAM-1	3383	UGCUACACAUGUCUAUGGAgg	UCCAUAGACAUGUGUAGCA	-2.4	-2.1	-0.9	0	1	2	-37.6	74.3	6.7	6	II	42.1	48	63	Luciferase reporter assay	T24	200nM	16h	Efficient reduction of target RNAs by small interfering RNA and RNase H-dependent antisense agents.	12500975	2003	Journal of Biological Chemistry	2003/2/1
MC2830	J03132	Vickers	ICAM-1	3383	CCCAAGCUGGCAUCCGUCAgg	UGACGGAUGCCAGCUUGGG	-2.1	-3.3	-1	0	-4	3	-44	38	-5.4	1	III	63.2	31.9	29	Luciferase reporter assay	T24	200nM	16h	Efficient reduction of target RNAs by small interfering RNA and RNase H-dependent antisense agents.	12500975	2003	Journal of Biological Chemistry	2003/2/1
MC2831	J03132	Vickers	ICAM-1	3383	GUGCCCAAGCUGGCAUCCGuc	CGGAUGCCAGCUUGGGCAC	-2.4	-2.2	-5.1	2	2	4	-45	35.2	0	0	II	68.4	45.4	24	Luciferase reporter assay	T24	200nM	16h	Efficient reduction of target RNAs by small interfering RNA and RNase H-dependent antisense agents.	12500975	2003	Journal of Biological Chemistry	2003/2/1
MC2832	J03132	Vickers	ICAM-1	3383	AGUGCCCAAGCUGGCAUCCgu	GGAUGCCAGCUUGGGCACU	-3.3	-2.1	-5.1	0	3	4	-44.7	47.7	8.1	2	II	63.2	50.5	40	Luciferase reporter assay	T24	200nM	16h	Efficient reduction of target RNAs by small interfering RNA and RNase H-dependent antisense agents.	12500975	2003	Journal of Biological Chemistry	2003/2/1
MC2833	J03132	Vickers	ICAM-1	3383	CUCCGUGAGGCCAGAGACCua	GGUCUCUGGCCUCACGGAG	-3.3	-2.1	-5.1	0	0	4	-45.6	29.3	-1.9	0	II	68.4	46.8	7	Luciferase reporter assay	T24	200nM	16h	Efficient reduction of target RNAs by small interfering RNA and RNase H-dependent antisense agents.	12500975	2003	Journal of Biological Chemistry	2003/2/1
MC2834	J03132	Vickers	ICAM-1	3383	AGGCACUCUCCUGCAGUGUac	ACACUGCAGGAGAGUGCCU	-2.2	-2.1	-2.1	3	0	3	-43.7	49	-0.6	3	II	57.9	44.6	0	Luciferase reporter assay	T24	200nM	16h	Efficient reduction of target RNAs by small interfering RNA and RNase H-dependent antisense agents.	12500975	2003	Journal of Biological Chemistry	2003/2/1
MC2835	J03132	Vickers	ICAM-1	3383	AAAGGCAGGUUGGCCAAUGag	CAUUGGCCAACCUGCCUUU	-2.1	-0.9	-3.3	2	3	4	-39.5	47	0	4	Ib	52.6	59.7	28	Luciferase reporter assay	T24	200nM	16h	Efficient reduction of target RNAs by small interfering RNA and RNase H-dependent antisense agents.	12500975	2003	Journal of Biological Chemistry	2003/2/1
MC2836	J03132	Vickers	ICAM-1	3383	GUAAUCUCUGAACCUGUGAac	UCACAGGUUCAGAGAUUAC	-2.4	-2.2	1.7	1	-1	2	-36.3	70.8	1	6	II	42.1	46.9	34	Luciferase reporter assay	T24	200nM	16h	Efficient reduction of target RNAs by small interfering RNA and RNase H-dependent antisense agents.	12500975	2003	Journal of Biological Chemistry	2003/2/1
MC2837	J03132	Vickers	ICAM-1	3383	UCCAGACAUGACCGCUGAGug	CUCAGCGGUCAUGUCUGGA	-2.1	-2.4	-1.1	-1	2	4	-42.2	45.4	2.4	2	II	57.9	45.7	33	Luciferase reporter assay	T24	200nM	16h	Efficient reduction of target RNAs by small interfering RNA and RNase H-dependent antisense agents.	12500975	2003	Journal of Biological Chemistry	2003/2/1
MC2838	J03132	Vickers	ICAM-1	3383	UGGAGCUGCAAUAGUGCAAgc	UUGCACUAUUGCAGCUCCA	-0.9	-2.1	-2.8	1	-1	2	-39.1	62.5	-1	5	II	47.4	49.2	5	Luciferase reporter assay	T24	200nM	16h	Efficient reduction of target RNAs by small interfering RNA and RNase H-dependent antisense agents.	12500975	2003	Journal of Biological Chemistry	2003/2/1
MC2839	J03132	Vickers	ICAM-1	3383	ACACAUACACACACACACAca	UGUGUGUGUGUGUAUGUGU	-2.1	-2.2	3.8	2	0	1	-36.8	55.7	-3.7	5	II	42.1	52.5	7	Luciferase reporter assay	T24	200nM	16h	Efficient reduction of target RNAs by small interfering RNA and RNase H-dependent antisense agents.	12500975	2003	Journal of Biological Chemistry	2003/2/1
MC2840	J03132	Vickers	ICAM-1	3383	CUGAGGUGGGAGGAUCACUug	AGUGAUCCUCCCACCUCAG	-2.1	-2.1	-0.9	1	-2	3	-43	42.7	-3.7	2	III	57.9	47.3	45	Luciferase reporter assay	T24	200nM	16h	Efficient reduction of target RNAs by small interfering RNA and RNase H-dependent antisense agents.	12500975	2003	Journal of Biological Chemistry	2003/2/1
MC2841	J03132	Vickers	ICAM-1	3383	GUGUGGUGUUGUGAGCCUAug	UAGGCUCACAACACCACAC	-1.3	-2.2	0.1	1	-2	3	-40.3	47.3	-0.7	3	III	52.6	35.2	41	Luciferase reporter assay	T24	200nM	16h	Efficient reduction of target RNAs by small interfering RNA and RNase H-dependent antisense agents.	12500975	2003	Journal of Biological Chemistry	2003/2/1
MC2842	J03132	Vickers	ICAM-1	3383	UAACACAAAGGAAGUCUGGgc	CCAGACUUCCUUUGUGUUA	-3.3	-1.3	0.4	0	4	2	-35.5	63.3	0.1	8	Ia	42.1	69.5	48	Luciferase reporter assay	T24	200nM	16h	Efficient reduction of target RNAs by small interfering RNA and RNase H-dependent antisense agents.	12500975	2003	Journal of Biological Chemistry	2003/2/1
MC2843	UYB79189	Takayuki Katoh	EGFP 	2315885245	CCUCGCCCUUGCUCACCAU	AUGGUGAGCAAGGGCGAGG	-1.1	-3.30 	-1.10 	0.00 	-2.00 	5.00 	-44	37.90 	-8.30 	-1.00 	III	63.20 	24.10 	54.75 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC2844	UYB79189	Takayuki Katoh	EGFP 	2315885245	UCCUCGCCCUUGCUCACCA	UGGUGAGCAAGGGCGAGGA	-2.1	-2.40 	-1.10 	1.00 	1.00 	5.00 	-45.3	52.40 	1.00 	2.00 	II	63.20 	48.60 	77.71 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC2845	UYB79189	Takayuki Katoh	EGFP 	2315885245	CUCCUCGCCCUUGCUCACC	GGUGAGCAAGGGCGAGGAG	-3.3	-2.10 	-1.10 	1.00 	0.00 	5.00 	-45.3	47.10 	8.40 	1.00 	II	68.40 	51.20 	60.16 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC2846	UYB79189	Takayuki Katoh	EGFP 	2315885245	GCUCCUCGCCCUUGCUCAC	GUGAGCAAGGGCGAGGAGC	-2.2	-3.40 	-1.10 	1.00 	1.00 	5.00 	-45.4	42.90 	8.10 	-1.00 	II	68.40 	29.60 	38.57 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC2847	UYB79189	Takayuki Katoh	EGFP 	2315885245	AGCUCCUCGCCCUUGCUCA	UGAGCAAGGGCGAGGAGCU	-2.1	-2.10 	-2.00 	3.00 	0.00 	5.00 	-45.3	61.00 	-6.10 	3.00 	II	63.20 	44.50 	65.08 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC2848	UYB79189	Takayuki Katoh	EGFP 	2315885245	CAGCUCCUCGCCCUUGCUC	GAGCAAGGGCGAGGAGCUG	-2.4	-2.10 	-2.70 	1.00 	1.00 	5.00 	-45.3	49.50 	5.40 	0.00 	II	68.40 	45.60 	44.55 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC2849	UYB79189	Takayuki Katoh	EGFP 	2315885245	ACAGCUCCUCGCCCUUGCU	AGCAAGGGCGAGGAGCUGU	-2.1	-2.20 	-2.70 	1.00 	2.00 	5.00 	-45.1	48.50 	-3.90 	1.00 	II	63.20 	44.70 	53.61 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC2850	UYB79189	Takayuki Katoh	EGFP 	2315885245	AACAGCUCCUCGCCCUUGC	GCAAGGGCGAGGAGCUGUU	-3.4	-0.90 	-2.70 	3.00 	3.00 	5.00 	-43.9	61.40 	7.50 	4.00 	Ib	63.20 	59.30 	75.64 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC2851	UYB79189	Takayuki Katoh	EGFP 	2315885245	GAACAGCUCCUCGCCCUUG	CAAGGGCGAGGAGCUGUUC	-2.1	-2.40 	-2.70 	2.00 	1.00 	5.00 	-42.9	38.70 	0.40 	2.00 	II	63.20 	45.00 	42.30 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC2852	UYB79189	Takayuki Katoh	EGFP 	2315885245	UGAACAGCUCCUCGCCCUU	AAGGGCGAGGAGCUGUUCA	-0.9	-2.10 	-2.90 	-1.00 	1.00 	5.00 	-42.9	50.00 	-0.90 	4.00 	II	57.90 	50.60 	56.28 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC2853	UYB79189	Takayuki Katoh	EGFP 	2315885245	GUGAACAGCUCCUCGCCCU	AGGGCGAGGAGCUGUUCAC	-2.1	-2.20 	-2.90 	1.00 	0.00 	5.00 	-44.2	47.70 	-6.00 	2.00 	II	63.20 	44.40 	73.97 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC2854	UYB79189	Takayuki Katoh	EGFP 	2315885245	GGUGAACAGCUCCUCGCCC	GGGCGAGGAGCUGUUCACC	-3.3	-3.30 	-2.70 	1.00 	3.00 	5.00 	-45.4	35.30 	12.50 	0.00 	II	68.40 	41.10 	52.45 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC2855	UYB79189	Takayuki Katoh	EGFP 	2315885245	CGGUGAACAGCUCCUCGCC	GGCGAGGAGCUGUUCACCG	-3.3	-2.40 	-2.30 	-1.00 	0.00 	4.00 	-44.5	43.20 	8.50 	0.00 	II	68.40 	43.90 	31.59 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC2856	UYB79189	Takayuki Katoh	EGFP 	2315885245	CCGGUGAACAGCUCCUCGC	GCGAGGAGCUGUUCACCGG	-3.4	-3.30 	-1.20 	0.00 	0.00 	4.00 	-44.5	45.40 	3.10 	1.00 	II	68.40 	50.40 	66.20 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC2857	UYB79189	Takayuki Katoh	EGFP 	2315885245	CCCGGUGAACAGCUCCUCG	CGAGGAGCUGUUCACCGGG	-2.4	-3.30 	-0.40 	-1.00 	0.00 	5.00 	-44.4	41.90 	5.00 	1.00 	II	68.40 	43.80 	39.28 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC2858	UYB79189	Takayuki Katoh	EGFP 	2315885245	CCCCGGUGAACAGCUCCUC	GAGGAGCUGUUCACCGGGG	-2.4	-3.30 	-0.40 	1.00 	-1.00 	6.00 	-45.3	30.30 	3.10 	1.00 	II	68.40 	40.40 	12.20 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC2859	UYB79189	Takayuki Katoh	EGFP 	2315885245	ACCCCGGUGAACAGCUCCU	AGGAGCUGUUCACCGGGGU	-2.1	-2.20 	-0.40 	2.00 	1.00 	6.00 	-45.1	39.80 	-6.60 	3.00 	II	63.20 	45.80 	50.06 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC2860	UYB79189	Takayuki Katoh	EGFP 	2315885245	CACCCCGGUGAACAGCUCC	GGAGCUGUUCACCGGGGUG	-3.3	-2.10 	-1.70 	0.00 	0.00 	6.00 	-45.1	44.00 	10.10 	1.00 	II	68.40 	49.80 	66.02 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC2861	UYB79189	Takayuki Katoh	EGFP 	2315885245	CCACCCCGGUGAACAGCUC	GAGCUGUUCACCGGGGUGG	-2.4	-3.30 	-3.00 	1.00 	0.00 	6.00 	-45.1	28.90 	2.80 	-1.00 	II	68.40 	34.60 	51.08 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC2862	UYB79189	Takayuki Katoh	EGFP 	2315885245	ACCACCCCGGUGAACAGCU	AGCUGUUCACCGGGGUGGU	-2.1	-2.20 	-3.40 	2.00 	1.00 	6.00 	-44.9	40.50 	-6.60 	1.00 	II	63.20 	46.00 	60.60 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC2863	UYB79189	Takayuki Katoh	EGFP 	2315885245	CACCACCCCGGUGAACAGC	GCUGUUCACCGGGGUGGUG	-3.4	-2.10 	-3.40 	1.00 	0.00 	6.00 	-44.9	38.20 	11.10 	0.00 	II	68.40 	42.60 	48.41 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC2864	UYB79189	Takayuki Katoh	EGFP 	2315885245	GCACCACCCCGGUGAACAG	CUGUUCACCGGGGUGGUGC	-2.1	-3.40 	-3.60 	1.00 	1.00 	6.00 	-44.9	30.00 	0.00 	-1.00 	II	68.40 	25.60 	33.58 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC2865	UYB79189	Takayuki Katoh	EGFP 	2315885245	GGCACCACCCCGGUGAACA	UGUUCACCGGGGUGGUGCC	-2.1	-3.30 	-3.60 	1.00 	-2.00 	6.00 	-46.1	40.70 	-3.80 	0.00 	III	68.40 	30.50 	54.98 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC2866	UYB79189	Takayuki Katoh	EGFP 	2315885245	GGGCACCACCCCGGUGAAC	GUUCACCGGGGUGGUGCCC	-2.2	-3.30 	-3.60 	1.00 	-1.00 	6.00 	-47.3	20.50 	5.40 	-1.00 	II	73.70 	22.90 	29.46 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC2867	UYB79189	Takayuki Katoh	EGFP 	2315885245	UGGGCACCACCCCGGUGAA	UUCACCGGGGUGGUGCCCA	-0.9	-2.10 	-4.90 	-1.00 	-1.00 	6.00 	-47.2	31.50 	-6.10 	1.00 	II	68.40 	29.30 	25.44 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC2868	UYB79189	Takayuki Katoh	EGFP 	2315885245	AUGGGCACCACCCCGGUGA	UCACCGGGGUGGUGCCCAU	-2.4	-1.10 	-4.90 	2.00 	0.00 	6.00 	-47.4	44.30 	-6.10 	4.00 	II	68.40 	50.50 	44.92 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC2869	UYB79189	Takayuki Katoh	EGFP 	2315885245	GAUGGGCACCACCCCGGUG	CACCGGGGUGGUGCCCAUC	-2.1	-2.40 	-4.90 	1.00 	2.00 	6.00 	-47.4	32.70 	2.40 	0.00 	II	73.70 	38.70 	30.48 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC2870	UYB79189	Takayuki Katoh	EGFP 	2315885245	GGAUGGGCACCACCCCGGU	ACCGGGGUGGUGCCCAUCC	-2.2	-3.30 	-5.90 	0.00 	0.00 	6.00 	-48.6	24.30 	-3.90 	1.00 	III	73.70 	30.40 	28.39 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC2871	UYB79189	Takayuki Katoh	EGFP 	2315885245	AGGAUGGGCACCACCCCGG	CCGGGGUGGUGCCCAUCCU	-3.3	-2.10 	-7.80 	2.00 	3.00 	6.00 	-48.5	37.60 	-7.30 	4.00 	II	73.70 	58.20 	47.66 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC2872	UYB79189	Takayuki Katoh	EGFP 	2315885245	CAGGAUGGGCACCACCCCG	CGGGGUGGUGCCCAUCCUG	-2.4	-2.10 	-9.40 	0.00 	1.00 	5.00 	-47.3	32.90 	3.10 	1.00 	II	73.70 	51.70 	32.44 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC2873	UYB79189	Takayuki Katoh	EGFP 	2315885245	CCAGGAUGGGCACCACCCC	GGGGUGGUGCCCAUCCUGG	-3.3	-3.30 	-8.20 	1.00 	1.00 	4.00 	-48.2	23.40 	5.50 	0.00 	II	73.70 	45.40 	17.03 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC2874	UYB79189	Takayuki Katoh	EGFP 	2315885245	ACCAGGAUGGGCACCACCC	GGGUGGUGCCCAUCCUGGU	-3.3	-2.20 	-7.10 	2.00 	3.00 	4.00 	-47.1	42.10 	2.50 	2.00 	II	68.40 	59.90 	61.00 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC2875	UYB79189	Takayuki Katoh	EGFP 	2315885245	GACCAGGAUGGGCACCACC	GGUGGUGCCCAUCCUGGUC	-3.3	-2.40 	-3.40 	1.00 	1.00 	4.00 	-46.2	34.80 	12.50 	1.00 	II	68.40 	47.50 	42.56 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC2876	UYB79189	Takayuki Katoh	EGFP 	2315885245	CGACCAGGAUGGGCACCAC	GUGGUGCCCAUCCUGGUCG	-2.2	-2.40 	-1.00 	0.00 	0.00 	4.00 	-45.3	27.20 	5.40 	0.00 	II	68.40 	31.50 	27.27 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC2877	UYB79189	Takayuki Katoh	EGFP 	2315885245	UCGACCAGGAUGGGCACCA	UGGUGCCCAUCCUGGUCGA	-2.1	-2.40 	-1.00 	0.00 	0.00 	4.00 	-45.5	40.40 	-3.80 	4.00 	II	63.20 	52.60 	52.46 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC2878	UYB79189	Takayuki Katoh	EGFP 	2315885245	CUCGACCAGGAUGGGCACC	GGUGCCCAUCCUGGUCGAG	-3.3	-2.10 	-1.00 	-1.00 	0.00 	4.00 	-45.5	35.20 	13.40 	0.00 	II	68.40 	42.80 	30.35 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC2879	UYB79189	Takayuki Katoh	EGFP 	2315885245	GCUCGACCAGGAUGGGCAC	GUGCCCAUCCUGGUCGAGC	-2.2	-3.40 	-1.00 	0.00 	1.00 	4.00 	-45.6	28.10 	7.40 	-1.00 	II	68.40 	25.20 	17.64 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC2880	UYB79189	Takayuki Katoh	EGFP 	2315885245	AGCUCGACCAGGAUGGGCA	UGCCCAUCCUGGUCGAGCU	-2.1	-2.10 	-1.00 	2.00 	1.00 	4.00 	-45.5	52.60 	-4.00 	3.00 	II	63.20 	46.70 	54.20 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC2881	UYB79189	Takayuki Katoh	EGFP 	2315885245	CAGCUCGACCAGGAUGGGC	GCCCAUCCUGGUCGAGCUG	-3.4	-2.10 	-0.80 	1.00 	1.00 	4.00 	-45.5	38.60 	7.70 	2.00 	II	68.40 	46.00 	39.76 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC2882	UYB79189	Takayuki Katoh	EGFP 	2315885245	CCAGCUCGACCAGGAUGGG	CCCAUCCUGGUCGAGCUGG	-3.3	-3.30 	-0.80 	-2.00 	1.00 	3.00 	-45.4	23.10 	-4.40 	0.00 	II	68.40 	31.70 	33.97 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC2883	UYB79189	Takayuki Katoh	EGFP 	2315885245	UCCAGCUCGACCAGGAUGG	CCAUCCUGGUCGAGCUGGA	-3.3	-2.40 	-1.90 	1.00 	2.00 	2.00 	-44.5	52.50 	-7.30 	5.00 	II	63.20 	61.20 	64.10 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC2884	UYB79189	Takayuki Katoh	EGFP 	2315885245	GUCCAGCUCGACCAGGAUG	CAUCCUGGUCGAGCUGGAC	-2.1	-2.20 	-1.90 	2.00 	0.00 	2.00 	-43.4	42.60 	5.10 	0.00 	II	63.20 	41.30 	59.28 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC2885	UYB79189	Takayuki Katoh	EGFP 	2315885245	CGUCCAGCUCGACCAGGAU	AUCCUGGUCGAGCUGGACG	-1.1	-2.40 	-2.50 	0.00 	-2.00 	2.00 	-43.7	34.60 	-3.60 	0.00 	III	63.20 	24.40 	31.37 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC2886	UYB79189	Takayuki Katoh	EGFP 	2315885245	CCGUCCAGCUCGACCAGGA	UCCUGGUCGAGCUGGACGG	-2.4	-3.30 	-2.50 	0.00 	-3.00 	3.00 	-45.9	34.60 	-10.70 	0.00 	III	68.40 	29.90 	48.78 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC2887	UYB79189	Takayuki Katoh	EGFP 	2315885245	GCCGUCCAGCUCGACCAGG	CCUGGUCGAGCUGGACGGC	-3.3	-3.40 	-2.50 	1.00 	0.00 	4.00 	-46.9	22.70 	-2.40 	-1.00 	II	73.70 	33.30 	33.94 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC2888	UYB79189	Takayuki Katoh	EGFP 	2315885245	CGCCGUCCAGCUCGACCAG	CUGGUCGAGCUGGACGGCG	-2.1	-2.40 	-3.30 	-1.00 	-1.00 	5.00 	-46	25.90 	1.10 	-2.00 	II	73.70 	26.00 	30.57 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC2889	UYB79189	Takayuki Katoh	EGFP 	2315885245	UCGCCGUCCAGCUCGACCA	UGGUCGAGCUGGACGGCGA	-2.1	-2.40 	-3.30 	3.00 	0.00 	5.00 	-46.3	52.80 	-6.10 	3.00 	II	68.40 	56.50 	76.83 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC2890	UYB79189	Takayuki Katoh	EGFP 	2315885245	GUCGCCGUCCAGCUCGACC	GGUCGAGCUGGACGGCGAC	-3.3	-2.20 	-3.30 	1.00 	2.00 	5.00 	-46.4	49.10 	14.40 	0.00 	II	73.70 	47.80 	71.54 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC2891	UYB79189	Takayuki Katoh	EGFP 	2315885245	CGUCGCCGUCCAGCUCGAC	GUCGAGCUGGACGGCGACG	-2.2	-2.40 	-3.50 	0.00 	0.00 	5.00 	-45.5	24.30 	3.10 	-1.00 	II	73.70 	28.70 	24.97 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC2892	UYB79189	Takayuki Katoh	EGFP 	2315885245	ACGUCGCCGUCCAGCUCGA	UCGAGCUGGACGGCGACGU	-2.4	-2.20 	-3.00 	1.00 	0.00 	5.00 	-45.5	28.80 	-11.00 	1.00 	II	68.40 	31.40 	28.91 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC2893	UYB79189	Takayuki Katoh	EGFP 	2315885245	UACGUCGCCGUCCAGCUCG	CGAGCUGGACGGCGACGUA	-2.4	-1.30 	-3.50 	1.00 	3.00 	5.00 	-44.4	53.70 	0.10 	5.00 	II	68.40 	70.40 	52.17 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC2894	UYB79189	Takayuki Katoh	EGFP 	2315885245	UUACGUCGCCGUCCAGCUC	GAGCUGGACGGCGACGUAA	-2.4	-0.90 	-3.50 	2.00 	4.00 	5.00 	-42.9	55.40 	12.80 	3.00 	Ib	63.20 	63.90 	59.28 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC2895	UYB79189	Takayuki Katoh	EGFP 	2315885245	UUUACGUCGCCGUCCAGCU	AGCUGGACGGCGACGUAAA	-2.1	-0.90 	-3.50 	2.00 	3.00 	5.00 	-41.4	67.90 	-6.30 	5.00 	II	57.90 	67.60 	44.73 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC2896	UYB79189	Takayuki Katoh	EGFP 	2315885245	GUUUACGUCGCCGUCCAGC	GCUGGACGGCGACGUAAAC	-3.4	-2.20 	-3.50 	1.00 	3.00 	5.00 	-41.5	53.90 	7.70 	3.00 	II	63.20 	51.50 	57.12 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC2897	UYB79189	Takayuki Katoh	EGFP 	2315885245	CGUUUACGUCGCCGUCCAG	CUGGACGGCGACGUAAACG	-2.1	-2.40 	-3.50 	-2.00 	0.00 	5.00 	-40.5	42.10 	-2.00 	1.00 	II	63.20 	29.40 	37.17 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC2898	UYB79189	Takayuki Katoh	EGFP 	2315885245	CCGUUUACGUCGCCGUCCA	UGGACGGCGACGUAAACGG	-2.1	-3.30 	-3.50 	0.00 	-3.00 	5.00 	-41.7	45.50 	-5.70 	1.00 	II	63.20 	34.60 	32.38 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC2899	UYB79189	Takayuki Katoh	EGFP 	2315885245	GCCGUUUACGUCGCCGUCC	GGACGGCGACGUAAACGGC	-3.3	-3.40 	-3.50 	2.00 	0.00 	5.00 	-43	43.90 	5.10 	1.00 	II	68.40 	48.70 	35.07 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC2900	UYB79189	Takayuki Katoh	EGFP 	2315885245	GGCCGUUUACGUCGCCGUC	GACGGCGACGUAAACGGCC	-2.4	-3.30 	-3.50 	1.00 	0.00 	5.00 	-43	42.30 	12.80 	-1.00 	II	68.40 	34.20 	44.73 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC2901	UYB79189	Takayuki Katoh	EGFP 	2315885245	UGGCCGUUUACGUCGCCGU	ACGGCGACGUAAACGGCCA	-2.2	-2.10 	-3.80 	2.00 	1.00 	5.00 	-42.7	57.00 	-6.30 	3.00 	II	63.20 	57.70 	68.59 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC2902	UYB79189	Takayuki Katoh	EGFP 	2315885245	GUGGCCGUUUACGUCGCCG	CGGCGACGUAAACGGCCAC	-2.4	-2.20 	-3.80 	0.00 	3.00 	5.00 	-42.7	45.80 	2.30 	0.00 	II	68.40 	48.10 	70.94 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC2903	UYB79189	Takayuki Katoh	EGFP 	2315885245	UGUGGCCGUUUACGUCGCC	GGCGACGUAAACGGCCACA	-3.3	-2.10 	-3.50 	-1.00 	4.00 	5.00 	-42.4	42.00 	9.80 	2.00 	II	63.20 	54.80 	44.03 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC2904	UYB79189	Takayuki Katoh	EGFP 	2315885245	UUGUGGCCGUUUACGUCGC	GCGACGUAAACGGCCACAA	-3.4	-0.90 	-0.50 	1.00 	4.00 	5.00 	-40	58.60 	7.80 	4.00 	II	57.90 	65.80 	49.96 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC2905	UYB79189	Takayuki Katoh	EGFP 	2315885245	CUUGUGGCCGUUUACGUCG	CGACGUAAACGGCCACAAG	-2.4	-2.10 	-0.50 	0.00 	1.00 	5.00 	-38.7	59.80 	1.00 	4.00 	II	57.90 	61.20 	57.87 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC2906	UYB79189	Takayuki Katoh	EGFP 	2315885245	ACUUGUGGCCGUUUACGUC	GACGUAAACGGCCACAAGU	-2.4	-2.20 	-0.50 	2.00 	4.00 	5.00 	-38.5	67.50 	12.80 	5.00 	Ib	52.60 	54.90 	53.64 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC2907	UYB79189	Takayuki Katoh	EGFP 	2315885245	AACUUGUGGCCGUUUACGU	ACGUAAACGGCCACAAGUU	-2.2	-0.90 	-0.50 	3.00 	3.00 	5.00 	-37	71.60 	-4.00 	6.00 	II	47.40 	55.80 	53.84 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC2908	UYB79189	Takayuki Katoh	EGFP 	2315885245	GAACUUGUGGCCGUUUACG	CGUAAACGGCCACAAGUUC	-2.4	-2.40 	0.00 	2.00 	3.00 	5.00 	-37.2	59.00 	-2.40 	4.00 	II	52.60 	53.90 	68.44 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC2909	UYB79189	Takayuki Katoh	EGFP 	2315885245	UGAACUUGUGGCCGUUUAC	GUAAACGGCCACAAGUUCA	-2.2	-2.10 	0.40 	0.00 	2.00 	5.00 	-36.9	74.60 	7.50 	7.00 	Ia	47.40 	61.80 	82.92 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC2910	UYB79189	Takayuki Katoh	EGFP 	2315885245	CUGAACUUGUGGCCGUUUA	UAAACGGCCACAAGUUCAG	-1.3	-2.10 	0.40 	1.00 	-4.00 	5.00 	-36.8	64.40 	-0.70 	5.00 	II	47.40 	39.00 	55.22 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC2911	UYB79189	Takayuki Katoh	EGFP 	2315885245	GCUGAACUUGUGGCCGUUU	AAACGGCCACAAGUUCAGC	-0.9	-3.40 	0.40 	0.00 	-2.00 	5.00 	-38.9	40.10 	-1.30 	3.00 	III	52.60 	30.10 	41.81 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC2912	UYB79189	Takayuki Katoh	EGFP 	2315885245	CGCUGAACUUGUGGCCGUU	AACGGCCACAAGUUCAGCG	-0.9	-2.40 	0.40 	-2.00 	-3.00 	5.00 	-40.4	37.80 	-3.00 	1.00 	III	57.90 	26.00 	42.70 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC2913	UYB79189	Takayuki Katoh	EGFP 	2315885245	ACGCUGAACUUGUGGCCGU	ACGGCCACAAGUUCAGCGU	-2.2	-2.20 	0.40 	2.00 	1.00 	5.00 	-41.7	40.40 	-4.00 	3.00 	II	57.90 	44.50 	68.07 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC2914	UYB79189	Takayuki Katoh	EGFP 	2315885245	CACGCUGAACUUGUGGCCG	CGGCCACAAGUUCAGCGUG	-2.4	-2.10 	0.30 	-1.00 	2.00 	5.00 	-41.6	50.00 	3.40 	1.00 	II	63.20 	50.70 	63.77 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC2915	UYB79189	Takayuki Katoh	EGFP 	2315885245	ACACGCUGAACUUGUGGCC	GGCCACAAGUUCAGCGUGU	-3.3	-2.20 	-0.30 	2.00 	4.00 	4.00 	-41.4	54.90 	8.10 	4.00 	II	57.90 	56.40 	59.21 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC2916	UYB79189	Takayuki Katoh	EGFP 	2315885245	GACACGCUGAACUUGUGGC	GCCACAAGUUCAGCGUGUC	-3.4	-2.40 	-0.30 	1.00 	3.00 	3.00 	-40.5	65.40 	9.70 	2.00 	II	57.90 	47.60 	74.71 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC2917	UYB79189	Takayuki Katoh	EGFP 	2315885245	GGACACGCUGAACUUGUGG	CCACAAGUUCAGCGUGUCC	-3.3	-3.30 	-0.30 	1.00 	2.00 	3.00 	-40.4	49.50 	9.70 	3.00 	II	57.90 	43.30 	84.19 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC2918	UYB79189	Takayuki Katoh	EGFP 	2315885245	CGGACACGCUGAACUUGUG	CACAAGUUCAGCGUGUCCG	-2.1	-2.40 	0.00 	0.00 	-1.00 	3.00 	-39.5	44.00 	-4.60 	0.00 	II	57.90 	34.30 	56.35 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC2919	UYB79189	Takayuki Katoh	EGFP 	2315885245	CCGGACACGCUGAACUUGU	ACAAGUUCAGCGUGUCCGG	-2.2	-3.30 	0.70 	0.00 	-3.00 	4.00 	-40.7	37.10 	-5.90 	2.00 	III	57.90 	39.20 	53.21 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC2920	UYB79189	Takayuki Katoh	EGFP 	2315885245	GCCGGACACGCUGAACUUG	CAAGUUCAGCGUGUCCGGC	-2.1	-3.40 	0.70 	1.00 	-1.00 	5.00 	-41.9	28.60 	0.70 	0.00 	II	63.20 	30.40 	57.54 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC2921	UYB79189	Takayuki Katoh	EGFP 	2315885245	CGCCGGACACGCUGAACUU	AAGUUCAGCGUGUCCGGCG	-0.9	-2.40 	-1.00 	-1.00 	-3.00 	6.00 	-42.2	31.30 	-8.30 	-1.00 	III	63.20 	28.20 	40.43 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC2922	UYB79189	Takayuki Katoh	EGFP 	2315885245	UCGCCGGACACGCUGAACU	AGUUCAGCGUGUCCGGCGA	-2.1	-2.40 	-1.00 	2.00 	1.00 	6.00 	-43.7	50.70 	-1.60 	3.00 	II	63.20 	57.30 	73.34 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC2923	UYB79189	Takayuki Katoh	EGFP 	2315885245	CUCGCCGGACACGCUGAAC	GUUCAGCGUGUCCGGCGAG	-2.2	-2.10 	-1.00 	-1.00 	-1.00 	6.00 	-43.7	40.40 	5.40 	0.00 	II	68.40 	38.30 	49.53 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC2924	UYB79189	Takayuki Katoh	EGFP 	2315885245	CCUCGCCGGACACGCUGAA	UUCAGCGUGUCCGGCGAGG	-0.9	-3.30 	-1.00 	0.00 	-3.00 	6.00 	-44.8	21.10 	-5.70 	0.00 	III	68.40 	16.30 	39.52 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC2925	UYB79189	Takayuki Katoh	EGFP 	2315885245	CCCUCGCCGGACACGCUGA	UCAGCGUGUCCGGCGAGGG	-2.4	-3.30 	-1.30 	0.00 	-4.00 	6.00 	-47.2	31.10 	-8.40 	0.00 	III	73.70 	25.50 	34.17 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC2926	UYB79189	Takayuki Katoh	EGFP 	2315885245	GCCCUCGCCGGACACGCUG	CAGCGUGUCCGGCGAGGGC	-2.1	-3.40 	-3.90 	2.00 	0.00 	6.00 	-48.2	26.20 	2.40 	0.00 	II	78.90 	34.40 	49.31 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC2927	UYB79189	Takayuki Katoh	EGFP 	2315885245	CGCCCUCGCCGGACACGCU	AGCGUGUCCGGCGAGGGCG	-2.1	-2.40 	-5.60 	1.00 	-2.00 	6.00 	-48.5	25.40 	-8.60 	-2.00 	III	78.90 	27.90 	49.20 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC2928	UYB79189	Takayuki Katoh	EGFP 	2315885245	UCGCCCUCGCCGGACACGC	GCGUGUCCGGCGAGGGCGA	-3.4	-2.40 	-5.80 	3.00 	3.00 	6.00 	-48.8	35.70 	5.10 	2.00 	II	78.90 	58.30 	38.91 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC2929	UYB79189	Takayuki Katoh	EGFP 	2315885245	CUCGCCCUCGCCGGACACG	CGUGUCCGGCGAGGGCGAG	-2.4	-2.10 	-5.80 	-1.00 	0.00 	6.00 	-47.5	26.80 	-6.70 	-1.00 	II	78.90 	39.40 	39.16 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC2930	UYB79189	Takayuki Katoh	EGFP 	2315885245	CCUCGCCCUCGCCGGACAC	GUGUCCGGCGAGGGCGAGG	-2.2	-3.30 	-5.80 	-1.00 	0.00 	6.00 	-48.4	24.80 	5.50 	-1.00 	II	78.90 	27.70 	40.00 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC2931	UYB79189	Takayuki Katoh	EGFP 	2315885245	CCCUCGCCCUCGCCGGACA	UGUCCGGCGAGGGCGAGGG	-2.1	-3.30 	-5.60 	0.00 	-4.00 	6.00 	-49.5	28.20 	-5.70 	-1.00 	III	78.90 	22.30 	51.32 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC2932	UYB79189	Takayuki Katoh	EGFP 	2315885245	GCCCUCGCCCUCGCCGGAC	GUCCGGCGAGGGCGAGGGC	-2.2	-3.40 	-5.60 	2.00 	0.00 	6.00 	-50.8	20.30 	5.10 	0.00 	II	84.20 	29.30 	52.80 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC2933	UYB79189	Takayuki Katoh	EGFP 	2315885245	CGCCCUCGCCCUCGCCGGA	UCCGGCGAGGGCGAGGGCG	-2.4	-2.40 	-1.40 	0.00 	-3.00 	6.00 	-51	18.70 	-2.70 	-2.00 	III	84.20 	17.50 	44.44 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC2934	UYB79189	Takayuki Katoh	EGFP 	2315885245	UCGCCCUCGCCCUCGCCGG	CCGGCGAGGGCGAGGGCGA	-3.3	-2.40 	-1.20 	3.00 	3.00 	6.00 	-51	39.30 	-4.70 	2.00 	II	84.20 	55.60 	34.77 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC2935	UYB79189	Takayuki Katoh	EGFP 	2315885245	AUCGCCCUCGCCCUCGCCG	CGGCGAGGGCGAGGGCGAU	-2.4	-1.10 	-1.10 	2.00 	5.00 	5.00 	-48.8	45.40 	0.00 	1.00 	II	78.90 	56.40 	30.26 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC2936	UYB79189	Takayuki Katoh	EGFP 	2315885245	CAUCGCCCUCGCCCUCGCC	GGCGAGGGCGAGGGCGAUG	-3.3	-2.10 	-1.10 	0.00 	2.00 	5.00 	-48.5	36.80 	5.50 	0.00 	II	78.90 	43.50 	38.74 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC2937	UYB79189	Takayuki Katoh	EGFP 	2315885245	GCAUCGCCCUCGCCCUCGC	GCGAGGGCGAGGGCGAUGC	-3.4	-3.40 	-1.10 	1.00 	2.00 	5.00 	-48.6	33.20 	7.50 	0.00 	II	78.90 	35.30 	33.45 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC2938	UYB79189	Takayuki Katoh	EGFP 	2315885245	GGCAUCGCCCUCGCCCUCG	CGAGGGCGAGGGCGAUGCC	-2.4	-3.30 	-2.00 	1.00 	0.00 	5.00 	-48.5	34.40 	-2.40 	2.00 	II	78.90 	41.90 	29.27 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC2939	UYB79189	Takayuki Katoh	EGFP 	2315885245	UGGCAUCGCCCUCGCCCUC	GAGGGCGAGGGCGAUGCCA	-2.4	-2.10 	-3.70 	1.00 	2.00 	5.00 	-48.2	38.10 	13.20 	2.00 	II	73.70 	51.90 	30.57 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC2940	UYB79189	Takayuki Katoh	EGFP 	2315885245	GUGGCAUCGCCCUCGCCCU	AGGGCGAGGGCGAUGCCAC	-2.1	-2.20 	-3.70 	2.00 	0.00 	5.00 	-48	37.90 	-8.70 	0.00 	III	73.70 	40.30 	39.74 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC2941	UYB79189	Takayuki Katoh	EGFP 	2315885245	GGUGGCAUCGCCCUCGCCC	GGGCGAGGGCGAUGCCACC	-3.3	-3.30 	-3.70 	1.00 	3.00 	5.00 	-49.2	37.90 	7.40 	0.00 	II	78.90 	46.30 	16.30 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC2942	UYB79189	Takayuki Katoh	EGFP 	2315885245	AGGUGGCAUCGCCCUCGCC	GGCGAGGGCGAUGCCACCU	-3.3	-2.10 	-3.70 	1.00 	3.00 	5.00 	-48	38.10 	7.50 	1.00 	II	73.70 	48.40 	39.33 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC2943	UYB79189	Takayuki Katoh	EGFP 	2315885245	UAGGUGGCAUCGCCCUCGC	GCGAGGGCGAUGCCACCUA	-3.4	-1.30 	-2.70 	0.00 	4.00 	5.00 	-46	49.10 	7.50 	4.00 	II	68.40 	64.80 	28.52 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC2944	UYB79189	Takayuki Katoh	EGFP 	2315885245	GUAGGUGGCAUCGCCCUCG	CGAGGGCGAUGCCACCUAC	-2.4	-2.20 	-2.70 	1.00 	2.00 	5.00 	-44.8	39.50 	-2.40 	3.00 	II	68.40 	56.90 	36.20 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC2945	UYB79189	Takayuki Katoh	EGFP 	2315885245	CGUAGGUGGCAUCGCCCUC	GAGGGCGAUGCCACCUACG	-2.4	-2.40 	-2.70 	0.00 	0.00 	5.00 	-44.8	40.40 	13.10 	1.00 	II	68.40 	41.80 	32.56 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC2946	UYB79189	Takayuki Katoh	EGFP 	2315885245	CCGUAGGUGGCAUCGCCCU	AGGGCGAUGCCACCUACGG	-2.1	-3.30 	-2.70 	0.00 	-2.00 	5.00 	-45.7	33.70 	-5.60 	1.00 	III	68.40 	38.10 	24.66 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC2947	UYB79189	Takayuki Katoh	EGFP 	2315885245	GCCGUAGGUGGCAUCGCCC	GGGCGAUGCCACCUACGGC	-3.3	-3.40 	-2.80 	0.00 	2.00 	5.00 	-47	32.10 	4.80 	0.00 	II	73.70 	42.20 	32.13 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC2948	UYB79189	Takayuki Katoh	EGFP 	2315885245	UGCCGUAGGUGGCAUCGCC	GGCGAUGCCACCUACGGCA	-3.3	-2.10 	-4.70 	2.00 	3.00 	4.00 	-45.8	44.80 	9.80 	2.00 	II	68.40 	58.50 	48.71 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC2949	UYB79189	Takayuki Katoh	EGFP 	2315885245	UUGCCGUAGGUGGCAUCGC	GCGAUGCCACCUACGGCAA	-3.4	-0.90 	-5.50 	3.00 	4.00 	4.00 	-43.4	48.60 	7.40 	3.00 	II	63.20 	67.70 	39.58 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC2950	UYB79189	Takayuki Katoh	EGFP 	2315885245	CUUGCCGUAGGUGGCAUCG	CGAUGCCACCUACGGCAAG	-2.4	-2.10 	-5.50 	-2.00 	1.00 	4.00 	-42.1	52.00 	1.00 	2.00 	II	63.20 	50.00 	54.41 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC2951	UYB79189	Takayuki Katoh	EGFP 	2315885245	GCUUGCCGUAGGUGGCAUC	GAUGCCACCUACGGCAAGC	-2.4	-3.40 	-5.50 	-1.00 	0.00 	4.00 	-43.1	45.50 	7.40 	1.00 	II	63.20 	33.70 	31.33 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC2952	UYB79189	Takayuki Katoh	EGFP 	2315885245	AGCUUGCCGUAGGUGGCAU	AUGCCACCUACGGCAAGCU	-1.1	-2.10 	-5.50 	2.00 	1.00 	4.00 	-42.8	49.00 	0.70 	2.00 	II	57.90 	34.30 	46.78 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC2953	UYB79189	Takayuki Katoh	EGFP 	2315885245	CAGCUUGCCGUAGGUGGCA	UGCCACCUACGGCAAGCUG	-2.1	-2.10 	-5.20 	0.00 	-2.00 	4.00 	-43.8	32.00 	-5.80 	1.00 	III	63.20 	37.60 	19.27 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC2954	UYB79189	Takayuki Katoh	EGFP 	2315885245	UCAGCUUGCCGUAGGUGGC	GCCACCUACGGCAAGCUGA	-3.4	-2.40 	-4.50 	1.00 	4.00 	4.00 	-44.1	55.80 	7.80 	3.00 	Ib	63.20 	61.70 	45.26 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC2955	UYB79189	Takayuki Katoh	EGFP 	2315885245	GUCAGCUUGCCGUAGGUGG	CCACCUACGGCAAGCUGAC	-3.3	-2.20 	-1.90 	2.00 	1.00 	4.00 	-42.9	54.70 	-2.40 	2.00 	II	63.20 	47.20 	55.83 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC2956	UYB79189	Takayuki Katoh	EGFP 	2315885245	GGUCAGCUUGCCGUAGGUG	CACCUACGGCAAGCUGACC	-2.1	-3.30 	-1.90 	1.00 	2.00 	4.00 	-42.9	35.20 	0.30 	0.00 	II	63.20 	33.90 	34.74 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC2957	UYB79189	Takayuki Katoh	EGFP 	2315885245	GGGUCAGCUUGCCGUAGGU	ACCUACGGCAAGCUGACCC	-2.2	-3.30 	-1.90 	-1.00 	-1.00 	4.00 	-44.1	37.60 	-3.90 	0.00 	III	63.20 	23.80 	39.10 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC2958	UYB79189	Takayuki Katoh	EGFP 	2315885245	AGGGUCAGCUUGCCGUAGG	CCUACGGCAAGCUGACCCU	-3.3	-2.10 	-1.90 	2.00 	2.00 	4.00 	-44	48.20 	2.40 	2.00 	II	63.20 	52.30 	67.73 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC2959	UYB79189	Takayuki Katoh	EGFP 	2315885245	CAGGGUCAGCUUGCCGUAG	CUACGGCAAGCUGACCCUG	-2.1	-2.10 	-1.90 	0.00 	-1.00 	4.00 	-42.8	39.80 	1.00 	0.00 	II	63.20 	40.70 	30.78 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC2960	UYB79189	Takayuki Katoh	EGFP 	2315885245	UCAGGGUCAGCUUGCCGUA	UACGGCAAGCUGACCCUGA	-1.3	-2.40 	-1.90 	0.00 	0.00 	4.00 	-43.1	44.80 	-3.10 	3.00 	II	57.90 	48.50 	48.47 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC2961	UYB79189	Takayuki Katoh	EGFP 	2315885245	UUCAGGGUCAGCUUGCCGU	ACGGCAAGCUGACCCUGAA	-2.2	-0.90 	-1.90 	1.00 	3.00 	4.00 	-42.7	66.70 	-4.00 	5.00 	II	57.90 	65.70 	74.98 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC2962	UYB79189	Takayuki Katoh	EGFP 	2315885245	CUUCAGGGUCAGCUUGCCG	CGGCAAGCUGACCCUGAAG	-2.4	-2.10 	-1.40 	0.00 	3.00 	4.00 	-42.6	48.30 	7.70 	2.00 	II	63.20 	51.90 	64.56 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC2963	UYB79189	Takayuki Katoh	EGFP 	2315885245	ACUUCAGGGUCAGCUUGCC	GGCAAGCUGACCCUGAAGU	-3.3	-2.20 	-0.20 	2.00 	4.00 	3.00 	-42.4	48.30 	5.10 	4.00 	Ib	57.90 	49.50 	62.57 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC2964	UYB79189	Takayuki Katoh	EGFP 	2315885245	AACUUCAGGGUCAGCUUGC	GCAAGCUGACCCUGAAGUU	-3.4	-0.90 	-0.80 	1.00 	3.00 	3.00 	-40	60.40 	2.50 	7.00 	Ia	52.60 	61.40 	69.63 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC2965	UYB79189	Takayuki Katoh	EGFP 	2315885245	GAACUUCAGGGUCAGCUUG	CAAGCUGACCCUGAAGUUC	-2.1	-2.40 	-0.90 	2.00 	1.00 	3.00 	-39	58.00 	5.40 	4.00 	II	52.60 	47.20 	71.75 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC2966	UYB79189	Takayuki Katoh	EGFP 	2315885245	UGAACUUCAGGGUCAGCUU	AAGCUGACCCUGAAGUUCA	-0.9	-2.10 	-0.90 	1.00 	1.00 	3.00 	-39	72.90 	-4.00 	6.00 	II	47.40 	60.00 	91.70 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC2967	UYB79189	Takayuki Katoh	EGFP 	2315885245	AUGAACUUCAGGGUCAGCU	AGCUGACCCUGAAGUUCAU	-2.1	-1.10 	-0.60 	3.00 	3.00 	3.00 	-39.2	73.00 	1.10 	7.00 	II	47.40 	65.00 	87.31 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC2968	UYB79189	Takayuki Katoh	EGFP 	2315885245	GAUGAACUUCAGGGUCAGC	GCUGACCCUGAAGUUCAUC	-3.4	-2.40 	0.00 	-1.00 	2.00 	3.00 	-39.5	46.30 	12.40 	3.00 	II	52.60 	40.20 	75.18 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC2969	UYB79189	Takayuki Katoh	EGFP 	2315885245	AGAUGAACUUCAGGGUCAG	CUGACCCUGAAGUUCAUCU	-2.1	-2.10 	1.10 	0.00 	3.00 	3.00 	-38.2	46.60 	-2.40 	5.00 	Ia	47.40 	45.50 	69.76 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC2970	UYB79189	Takayuki Katoh	EGFP 	2315885245	CAGAUGAACUUCAGGGUCA	UGACCCUGAAGUUCAUCUG	-2.1	-2.10 	1.10 	-1.00 	-3.00 	3.00 	-38.2	51.20 	-10.70 	5.00 	II	47.40 	45.20 	50.09 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC2971	UYB79189	Takayuki Katoh	EGFP 	2315885245	GCAGAUGAACUUCAGGGUC	GACCCUGAAGUUCAUCUGC	-2.4	-3.40 	1.20 	0.00 	1.00 	3.00 	-39.5	46.00 	15.50 	3.00 	II	52.60 	44.00 	43.50 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC2972	UYB79189	Takayuki Katoh	EGFP 	2315885245	UGCAGAUGAACUUCAGGGU	ACCCUGAAGUUCAUCUGCA	-2.2	-2.10 	0.20 	1.00 	1.00 	3.00 	-39.2	67.00 	-3.30 	6.00 	II	47.40 	55.10 	78.90 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC2973	UYB79189	Takayuki Katoh	EGFP 	2315885245	GUGCAGAUGAACUUCAGGG	CCCUGAAGUUCAUCUGCAC	-3.3	-2.20 	0.20 	2.00 	3.00 	3.00 	-39.2	61.10 	5.00 	4.00 	II	52.60 	56.00 	79.01 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC2974	UYB79189	Takayuki Katoh	EGFP 	2315885245	GGUGCAGAUGAACUUCAGG	CCUGAAGUUCAUCUGCACC	-3.3	-3.30 	0.20 	0.00 	2.00 	2.00 	-39.2	52.20 	7.00 	2.00 	II	52.60 	41.90 	68.12 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC2975	UYB79189	Takayuki Katoh	EGFP 	2315885245	UGGUGCAGAUGAACUUCAG	CUGAAGUUCAUCUGCACCA	-2.1	-2.10 	0.20 	0.00 	2.00 	2.00 	-38	62.40 	-2.60 	5.00 	II	47.40 	55.20 	67.42 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC2976	UYB79189	Takayuki Katoh	EGFP 	2315885245	GUGGUGCAGAUGAACUUCA	UGAAGUUCAUCUGCACCAC	-2.1	-2.20 	0.20 	1.00 	-2.00 	2.00 	-38.1	49.00 	-6.30 	4.00 	III	47.40 	44.50 	45.42 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC2977	UYB79189	Takayuki Katoh	EGFP 	2315885245	GGUGGUGCAGAUGAACUUC	GAAGUUCAUCUGCACCACC	-2.4	-3.30 	0.20 	0.00 	0.00 	2.00 	-39.3	50.80 	12.70 	3.00 	II	52.60 	43.70 	53.05 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC2978	UYB79189	Takayuki Katoh	EGFP 	2315885245	CGGUGGUGCAGAUGAACUU	AAGUUCAUCUGCACCACCG	-0.9	-2.40 	0.20 	0.00 	-3.00 	3.00 	-39.3	47.30 	-6.00 	3.00 	III	52.60 	37.40 	58.69 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC2979	UYB79189	Takayuki Katoh	EGFP 	2315885245	CCGGUGGUGCAGAUGAACU	AGUUCAUCUGCACCACCGG	-2.1	-3.30 	0.20 	0.00 	-2.00 	4.00 	-41.7	44.60 	-3.90 	1.00 	III	57.90 	41.60 	38.37 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC2980	UYB79189	Takayuki Katoh	EGFP 	2315885245	GCCGGUGGUGCAGAUGAAC	GUUCAUCUGCACCACCGGC	-2.2	-3.40 	0.40 	0.00 	-1.00 	5.00 	-43	28.00 	5.10 	0.00 	II	63.20 	33.00 	13.09 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC2981	UYB79189	Takayuki Katoh	EGFP 	2315885245	UGCCGGUGGUGCAGAUGAA	UUCAUCUGCACCACCGGCA	-0.9	-2.10 	-0.60 	2.00 	-1.00 	5.00 	-42.9	35.40 	-8.70 	3.00 	II	57.90 	34.80 	21.77 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC2982	UYB79189	Takayuki Katoh	EGFP 	2315885245	UUGCCGGUGGUGCAGAUGA	UCAUCUGCACCACCGGCAA	-2.4	-0.90 	-1.40 	2.00 	0.00 	5.00 	-42.9	50.70 	-1.40 	4.00 	II	57.90 	57.70 	48.50 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC2983	UYB79189	Takayuki Katoh	EGFP 	2315885245	CUUGCCGGUGGUGCAGAUG	CAUCUGCACCACCGGCAAG	-2.1	-2.10 	-1.40 	-1.00 	0.00 	5.00 	-42.6	46.20 	1.00 	1.00 	II	63.20 	44.80 	40.68 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC2984	UYB79189	Takayuki Katoh	EGFP 	2315885245	GCUUGCCGGUGGUGCAGAU	AUCUGCACCACCGGCAAGC	-1.1	-3.40 	-1.40 	0.00 	-1.00 	5.00 	-43.9	35.50 	-4.00 	0.00 	III	63.20 	16.60 	6.00 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC2985	UYB79189	Takayuki Katoh	EGFP 	2315885245	AGCUUGCCGGUGGUGCAGA	UCUGCACCACCGGCAAGCU	-2.4	-2.10 	-1.40 	2.00 	0.00 	5.00 	-44.9	40.30 	-1.40 	2.00 	II	63.20 	37.50 	4.35 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC2986	UYB79189	Takayuki Katoh	EGFP 	2315885245	CAGCUUGCCGGUGGUGCAG	CUGCACCACCGGCAAGCUG	-2.1	-2.10 	-1.40 	0.00 	0.00 	5.00 	-44.6	39.80 	1.00 	1.00 	II	68.40 	39.60 	32.40 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC2987	UYB79189	Takayuki Katoh	EGFP 	2315885245	GCAGCUUGCCGGUGGUGCA	UGCACCACCGGCAAGCUGC	-2.1	-3.40 	-1.30 	1.00 	-1.00 	5.00 	-45.9	37.70 	-3.80 	0.00 	III	68.40 	29.10 	3.82 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC2988	UYB79189	Takayuki Katoh	EGFP 	2315885245	GGCAGCUUGCCGGUGGUGC	GCACCACCGGCAAGCUGCC	-3.4	-3.30 	-3.20 	2.00 	1.00 	5.00 	-47.1	41.70 	7.40 	1.00 	II	73.70 	38.10 	35.37 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC2989	UYB79189	Takayuki Katoh	EGFP 	2315885245	GGGCAGCUUGCCGGUGGUG	CACCACCGGCAAGCUGCCC	-2.1	-3.30 	-4.00 	0.00 	0.00 	5.00 	-47	17.60 	-2.00 	-1.00 	II	73.70 	26.10 	20.78 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC2990	UYB79189	Takayuki Katoh	EGFP 	2315885245	CGGGCAGCUUGCCGGUGGU	ACCACCGGCAAGCUGCCCG	-2.2	-2.40 	-4.00 	-2.00 	-2.00 	5.00 	-47.3	24.20 	-5.90 	-1.00 	III	73.70 	23.20 	4.65 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC2991	UYB79189	Takayuki Katoh	EGFP 	2315885245	ACGGGCAGCUUGCCGGUGG	CCACCGGCAAGCUGCCCGU	-3.3	-2.20 	-4.00 	2.00 	2.00 	5.00 	-47.3	34.20 	2.40 	2.00 	II	73.70 	48.60 	38.78 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC2992	UYB79189	Takayuki Katoh	EGFP 	2315885245	CACGGGCAGCUUGCCGGUG	CACCGGCAAGCUGCCCGUG	-2.1	-2.10 	-4.00 	0.00 	0.00 	5.00 	-46.1	24.40 	1.00 	-1.00 	II	73.70 	37.40 	19.62 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC2993	UYB79189	Takayuki Katoh	EGFP 	2315885245	GCACGGGCAGCUUGCCGGU	ACCGGCAAGCUGCCCGUGC	-2.2	-3.40 	-4.00 	0.00 	0.00 	5.00 	-47.4	20.70 	-3.30 	0.00 	III	73.70 	27.50 	16.84 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC2994	UYB79189	Takayuki Katoh	EGFP 	2315885245	GGCACGGGCAGCUUGCCGG	CCGGCAAGCUGCCCGUGCC	-3.3	-3.30 	-4.00 	1.00 	2.00 	5.00 	-48.5	40.20 	0.00 	1.00 	II	78.90 	40.50 	46.16 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC2995	UYB79189	Takayuki Katoh	EGFP 	2315885245	GGGCACGGGCAGCUUGCCG	CGGCAAGCUGCCCGUGCCC	-2.4	-3.30 	-4.00 	2.00 	2.00 	5.00 	-48.5	28.90 	9.70 	0.00 	II	78.90 	35.80 	27.60 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC2996	UYB79189	Takayuki Katoh	EGFP 	2315885245	AGGGCACGGGCAGCUUGCC	GGCAAGCUGCCCGUGCCCU	-3.3	-2.10 	-3.70 	2.00 	3.00 	5.00 	-48.2	27.60 	5.10 	0.00 	II	73.70 	44.60 	30.66 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC2997	UYB79189	Takayuki Katoh	EGFP 	2315885245	CAGGGCACGGGCAGCUUGC	GCAAGCUGCCCGUGCCCUG	-3.4	-2.10 	-0.50 	-1.00 	0.00 	5.00 	-47	32.30 	0.50 	2.00 	II	73.70 	46.30 	56.01 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC2998	UYB79189	Takayuki Katoh	EGFP 	2315885245	CCAGGGCACGGGCAGCUUG	CAAGCUGCCCGUGCCCUGG	-2.1	-3.30 	-0.50 	0.00 	-1.00 	5.00 	-46.9	25.00 	0.40 	1.00 	II	73.70 	37.60 	46.31 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC2999	UYB79189	Takayuki Katoh	EGFP 	2315885245	GCCAGGGCACGGGCAGCUU	AAGCUGCCCGUGCCCUGGC	-0.9	-3.40 	-1.90 	0.00 	-2.00 	5.00 	-48.2	19.40 	-4.00 	0.00 	III	73.70 	22.50 	18.03 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3000	UYB79189	Takayuki Katoh	EGFP 	2315885245	GGCCAGGGCACGGGCAGCU	AGCUGCCCGUGCCCUGGCC	-2.1	-3.30 	-2.70 	1.00 	-1.00 	5.00 	-50.6	12.70 	-3.60 	1.00 	III	78.90 	27.50 	8.49 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3001	UYB79189	Takayuki Katoh	EGFP 	2315885245	GGGCCAGGGCACGGGCAGC	GCUGCCCGUGCCCUGGCCC	-3.4	-3.30 	-2.70 	1.00 	0.00 	5.00 	-51.8	11.80 	7.40 	-1.00 	II	84.20 	27.30 	28.76 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3002	UYB79189	Takayuki Katoh	EGFP 	2315885245	UGGGCCAGGGCACGGGCAG	CUGCCCGUGCCCUGGCCCA	-2.1	-2.10 	-2.70 	0.00 	2.00 	5.00 	-50.5	27.20 	0.10 	2.00 	II	78.90 	46.70 	26.39 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3003	UYB79189	Takayuki Katoh	EGFP 	2315885245	GUGGGCCAGGGCACGGGCA	UGCCCGUGCCCUGGCCCAC	-2.1	-2.20 	-2.70 	1.00 	-1.00 	5.00 	-50.6	19.00 	-8.70 	-1.00 	III	78.90 	29.10 	23.68 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3004	UYB79189	Takayuki Katoh	EGFP 	2315885245	GGUGGGCCAGGGCACGGGC	GCCCGUGCCCUGGCCCACC	-3.4	-3.30 	-2.70 	0.00 	2.00 	5.00 	-51.8	19.40 	9.80 	-1.00 	II	84.20 	33.00 	14.96 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3005	UYB79189	Takayuki Katoh	EGFP 	2315885245	GGGUGGGCCAGGGCACGGG	CCCGUGCCCUGGCCCACCC	-3.3	-3.30 	-1.50 	1.00 	1.00 	5.00 	-51.7	19.90 	0.00 	1.00 	II	84.20 	34.60 	8.36 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3006	UYB79189	Takayuki Katoh	EGFP 	2315885245	AGGGUGGGCCAGGGCACGG	CCGUGCCCUGGCCCACCCU	-3.3	-2.10 	-1.50 	1.00 	3.00 	5.00 	-50.5	22.20 	2.30 	2.00 	II	78.90 	46.90 	5.09 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3007	UYB79189	Takayuki Katoh	EGFP 	2315885245	GAGGGUGGGCCAGGGCACG	CGUGCCCUGGCCCACCCUC	-2.4	-2.40 	-1.50 	0.00 	1.00 	5.00 	-49.6	15.00 	-2.40 	0.00 	II	78.90 	38.80 	29.25 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3008	UYB79189	Takayuki Katoh	EGFP 	2315885245	CGAGGGUGGGCCAGGGCAC	GUGCCCUGGCCCACCCUCG	-2.2	-2.40 	-1.50 	0.00 	0.00 	5.00 	-49.6	15.30 	-1.90 	0.00 	II	78.90 	36.40 	0.00 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3009	UYB79189	Takayuki Katoh	EGFP 	2315885245	ACGAGGGUGGGCCAGGGCA	UGCCCUGGCCCACCCUCGU	-2.1	-2.20 	-1.50 	2.00 	0.00 	5.00 	-49.6	26.90 	-3.70 	2.00 	II	73.70 	40.50 	0.01 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3010	UYB79189	Takayuki Katoh	EGFP 	2315885245	CACGAGGGUGGGCCAGGGC	GCCCUGGCCCACCCUCGUG	-3.4	-2.10 	-1.50 	-1.00 	1.00 	5.00 	-49.6	24.40 	10.50 	1.00 	II	78.90 	41.60 	22.78 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3011	UYB79189	Takayuki Katoh	EGFP 	2315885245	UCACGAGGGUGGGCCAGGG	CCCUGGCCCACCCUCGUGA	-3.3	-2.40 	-1.00 	2.00 	4.00 	5.00 	-48.6	26.60 	0.00 	3.00 	II	73.70 	51.80 	25.31 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3012	UYB79189	Takayuki Katoh	EGFP 	2315885245	GUCACGAGGGUGGGCCAGG	CCUGGCCCACCCUCGUGAC	-3.3	-2.20 	-1.00 	0.00 	1.00 	5.00 	-47.5	26.00 	0.00 	1.00 	II	73.70 	41.40 	30.95 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3013	UYB79189	Takayuki Katoh	EGFP 	2315885245	GGUCACGAGGGUGGGCCAG	CUGGCCCACCCUCGUGACC	-2.1	-3.30 	-1.00 	1.00 	1.00 	5.00 	-47.5	23.70 	5.70 	1.00 	II	73.70 	26.70 	24.32 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3014	UYB79189	Takayuki Katoh	EGFP 	2315885245	UGGUCACGAGGGUGGGCCA	UGGCCCACCCUCGUGACCA	-2.1	-2.10 	-1.00 	-1.00 	0.00 	5.00 	-47.5	41.00 	-3.80 	2.00 	II	68.40 	39.50 	71.33 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3015	UYB79189	Takayuki Katoh	EGFP 	2315885245	GUGGUCACGAGGGUGGGCC	GGCCCACCCUCGUGACCAC	-3.3	-2.20 	-1.00 	1.00 	3.00 	5.00 	-47.6	43.10 	9.70 	2.00 	II	73.70 	50.90 	50.96 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3016	UYB79189	Takayuki Katoh	EGFP 	2315885245	GGUGGUCACGAGGGUGGGC	GCCCACCCUCGUGACCACC	-3.4	-3.30 	-1.00 	0.00 	2.00 	4.00 	-47.6	26.40 	9.70 	-1.00 	II	73.70 	32.00 	43.92 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3017	UYB79189	Takayuki Katoh	EGFP 	2315885245	GGGUGGUCACGAGGGUGGG	CCCACCCUCGUGACCACCC	-3.3	-3.30 	-1.00 	0.00 	1.00 	3.00 	-47.5	26.70 	0.00 	0.00 	II	73.70 	31.00 	20.39 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3018	UYB79189	Takayuki Katoh	EGFP 	2315885245	AGGGUGGUCACGAGGGUGG	CCACCCUCGUGACCACCCU	-3.3	-2.10 	-1.00 	1.00 	2.00 	3.00 	-46.3	39.00 	-4.90 	4.00 	II	68.40 	52.70 	33.94 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3019	UYB79189	Takayuki Katoh	EGFP 	2315885245	CAGGGUGGUCACGAGGGUG	CACCCUCGUGACCACCCUG	-2.1	-2.10 	-0.70 	-1.00 	0.00 	3.00 	-45.1	31.40 	-2.10 	1.00 	II	68.40 	44.20 	26.50 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3020	UYB79189	Takayuki Katoh	EGFP 	2315885245	UCAGGGUGGUCACGAGGGU	ACCCUCGUGACCACCCUGA	-2.2	-2.40 	1.10 	1.00 	2.00 	3.00 	-45.4	29.50 	-3.90 	4.00 	II	63.20 	46.40 	37.21 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3021	UYB79189	Takayuki Katoh	EGFP 	2315885245	GUCAGGGUGGUCACGAGGG	CCCUCGUGACCACCCUGAC	-3.3	-2.20 	1.10 	1.00 	2.00 	3.00 	-45.4	35.40 	-4.90 	2.00 	II	68.40 	47.50 	42.44 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3022	UYB79189	Takayuki Katoh	EGFP 	2315885245	GGUCAGGGUGGUCACGAGG	CCUCGUGACCACCCUGACC	-3.3	-3.30 	1.10 	1.00 	1.00 	3.00 	-45.4	35.20 	8.10 	2.00 	II	68.40 	39.40 	50.73 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3023	UYB79189	Takayuki Katoh	EGFP 	2315885245	AGGUCAGGGUGGUCACGAG	CUCGUGACCACCCUGACCU	-2.1	-2.10 	1.10 	2.00 	2.00 	3.00 	-44.2	44.10 	0.00 	3.00 	II	63.20 	39.30 	56.98 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3024	UYB79189	Takayuki Katoh	EGFP 	2315885245	UAGGUCAGGGUGGUCACGA	UCGUGACCACCCUGACCUA	-2.4	-1.30 	1.10 	1.00 	2.00 	3.00 	-43.4	49.80 	-1.40 	5.00 	II	57.90 	59.90 	51.78 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3025	UYB79189	Takayuki Katoh	EGFP 	2315885245	GUAGGUCAGGGUGGUCACG	CGUGACCACCCUGACCUAC	-2.4	-2.20 	1.10 	0.00 	2.00 	3.00 	-43.2	37.30 	3.00 	1.00 	II	63.20 	43.70 	47.12 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3026	UYB79189	Takayuki Katoh	EGFP 	2315885245	CGUAGGUCAGGGUGGUCAC	GUGACCACCCUGACCUACG	-2.2	-2.40 	1.30 	-1.00 	0.00 	3.00 	-43.2	47.30 	5.40 	2.00 	II	63.20 	38.70 	66.14 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3027	UYB79189	Takayuki Katoh	EGFP 	2315885245	CCGUAGGUCAGGGUGGUCA	UGACCACCCUGACCUACGG	-2.1	-3.30 	0.60 	0.00 	-3.00 	3.00 	-44.3	44.30 	-0.70 	4.00 	III	63.20 	36.40 	41.76 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3028	UYB79189	Takayuki Katoh	EGFP 	2315885245	GCCGUAGGUCAGGGUGGUC	GACCACCCUGACCUACGGC	-2.4	-3.40 	0.20 	-1.00 	0.00 	4.00 	-45.6	24.70 	9.70 	1.00 	II	68.40 	27.40 	30.04 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3029	UYB79189	Takayuki Katoh	EGFP 	2315885245	CGCCGUAGGUCAGGGUGGU	ACCACCCUGACCUACGGCG	-2.2	-2.40 	0.20 	0.00 	-2.00 	5.00 	-45.6	20.10 	-8.30 	0.00 	III	68.40 	24.30 	45.21 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3030	UYB79189	Takayuki Katoh	EGFP 	2315885245	ACGCCGUAGGUCAGGGUGG	CCACCCUGACCUACGGCGU	-3.3	-2.20 	0.20 	3.00 	2.00 	5.00 	-45.6	33.50 	-4.90 	3.00 	II	68.40 	50.00 	56.78 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3031	UYB79189	Takayuki Katoh	EGFP 	2315885245	CACGCCGUAGGUCAGGGUG	CACCCUGACCUACGGCGUG	-2.1	-2.10 	0.20 	-1.00 	0.00 	5.00 	-44.4	46.10 	3.40 	1.00 	II	68.40 	41.60 	74.33 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3032	UYB79189	Takayuki Katoh	EGFP 	2315885245	GCACGCCGUAGGUCAGGGU	ACCCUGACCUACGGCGUGC	-2.2	-3.40 	0.20 	1.00 	0.00 	5.00 	-45.7	31.00 	-4.00 	1.00 	III	68.40 	27.40 	67.12 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3033	UYB79189	Takayuki Katoh	EGFP 	2315885245	UGCACGCCGUAGGUCAGGG	CCCUGACCUACGGCGUGCA	-3.3	-2.10 	0.20 	1.00 	4.00 	5.00 	-45.6	47.90 	4.60 	3.00 	II	68.40 	53.20 	55.76 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3034	UYB79189	Takayuki Katoh	EGFP 	2315885245	CUGCACGCCGUAGGUCAGG	CCUGACCUACGGCGUGCAG	-3.3	-2.10 	0.30 	0.00 	0.00 	5.00 	-44.4	27.60 	0.70 	2.00 	II	68.40 	44.20 	47.98 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3035	UYB79189	Takayuki Katoh	EGFP 	2315885245	ACUGCACGCCGUAGGUCAG	CUGACCUACGGCGUGCAGU	-2.1	-2.20 	0.60 	1.00 	3.00 	5.00 	-43.3	41.50 	0.40 	2.00 	II	63.20 	38.10 	56.34 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3036	UYB79189	Takayuki Katoh	EGFP 	2315885245	CACUGCACGCCGUAGGUCA	UGACCUACGGCGUGCAGUG	-2.1	-2.10 	0.30 	0.00 	-3.00 	5.00 	-43.3	47.10 	-8.10 	3.00 	III	63.20 	38.30 	57.96 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3037	UYB79189	Takayuki Katoh	EGFP 	2315885245	GCACUGCACGCCGUAGGUC	GACCUACGGCGUGCAGUGC	-2.4	-3.40 	0.10 	2.00 	2.00 	5.00 	-44.6	29.30 	5.00 	1.00 	II	68.40 	36.00 	60.14 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3038	UYB79189	Takayuki Katoh	EGFP 	2315885245	AGCACUGCACGCCGUAGGU	ACCUACGGCGUGCAGUGCU	-2.2	-2.10 	-1.50 	0.00 	1.00 	5.00 	-44.3	46.80 	-3.90 	2.00 	II	63.20 	39.40 	55.68 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3039	UYB79189	Takayuki Katoh	EGFP 	2315885245	AAGCACUGCACGCCGUAGG	CCUACGGCGUGCAGUGCUU	-3.3	-0.90 	-1.60 	4.00 	3.00 	5.00 	-43	54.80 	2.80 	4.00 	Ib	63.20 	59.80 	70.09 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3040	UYB79189	Takayuki Katoh	EGFP 	2315885245	GAAGCACUGCACGCCGUAG	CUACGGCGUGCAGUGCUUC	-2.1	-2.40 	-1.60 	1.00 	1.00 	5.00 	-42.1	42.00 	-0.10 	1.00 	II	63.20 	37.00 	59.69 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3041	UYB79189	Takayuki Katoh	EGFP 	2315885245	UGAAGCACUGCACGCCGUA	UACGGCGUGCAGUGCUUCA	-1.3	-2.10 	-1.60 	-1.00 	0.00 	5.00 	-42.1	41.60 	-3.70 	4.00 	II	57.90 	48.90 	56.49 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3042	UYB79189	Takayuki Katoh	EGFP 	2315885245	CUGAAGCACUGCACGCCGU	ACGGCGUGCAGUGCUUCAG	-2.2	-2.10 	-1.60 	0.00 	-1.00 	5.00 	-42.9	38.70 	-8.20 	1.00 	III	63.20 	40.50 	62.10 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3043	UYB79189	Takayuki Katoh	EGFP 	2315885245	GCUGAAGCACUGCACGCCG	CGGCGUGCAGUGCUUCAGC	-2.4	-3.40 	-1.60 	0.00 	2.00 	5.00 	-44.1	29.80 	5.10 	1.00 	II	68.40 	41.40 	59.09 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3044	UYB79189	Takayuki Katoh	EGFP 	2315885245	GGCUGAAGCACUGCACGCC	GGCGUGCAGUGCUUCAGCC	-3.3	-3.30 	-2.10 	1.00 	1.00 	4.00 	-45	38.30 	8.10 	1.00 	II	68.40 	41.20 	71.76 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3045	UYB79189	Takayuki Katoh	EGFP 	2315885245	CGGCUGAAGCACUGCACGC	GCGUGCAGUGCUUCAGCCG	-3.4	-2.40 	-0.80 	0.00 	0.00 	4.00 	-44.1	36.00 	5.40 	1.00 	II	68.40 	43.90 	50.73 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3046	UYB79189	Takayuki Katoh	EGFP 	2315885245	GCGGCUGAAGCACUGCACG	CGUGCAGUGCUUCAGCCGC	-2.4	-3.40 	-0.30 	0.00 	1.00 	5.00 	-44.1	37.70 	2.40 	0.00 	II	68.40 	41.90 	79.54 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3047	UYB79189	Takayuki Katoh	EGFP 	2315885245	AGCGGCUGAAGCACUGCAC	GUGCAGUGCUUCAGCCGCU	-2.2	-2.10 	-0.60 	2.00 	2.00 	5.00 	-43.8	48.60 	2.50 	3.00 	II	63.20 	49.80 	90.24 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3048	UYB79189	Takayuki Katoh	EGFP 	2315885245	UAGCGGCUGAAGCACUGCA	UGCAGUGCUUCAGCCGCUA	-2.1	-1.30 	-1.30 	2.00 	1.00 	5.00 	-42.9	50.40 	1.00 	3.00 	II	57.90 	55.90 	81.99 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3049	UYB79189	Takayuki Katoh	EGFP 	2315885245	GUAGCGGCUGAAGCACUGC	GCAGUGCUUCAGCCGCUAC	-3.4	-2.20 	-1.30 	0.00 	2.00 	5.00 	-43	39.80 	9.70 	2.00 	II	63.20 	50.40 	73.57 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3050	UYB79189	Takayuki Katoh	EGFP 	2315885245	GGUAGCGGCUGAAGCACUG	CAGUGCUUCAGCCGCUACC	-2.1	-3.30 	-1.30 	0.00 	1.00 	5.00 	-42.9	34.90 	-2.60 	1.00 	II	63.20 	36.50 	81.25 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3051	UYB79189	Takayuki Katoh	EGFP 	2315885245	GGGUAGCGGCUGAAGCACU	AGUGCUUCAGCCGCUACCC	-2.1	-3.30 	-1.00 	1.00 	-2.00 	5.00 	-44.1	29.20 	-3.90 	0.00 	III	63.20 	32.40 	87.12 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3052	UYB79189	Takayuki Katoh	EGFP 	2315885245	GGGGUAGCGGCUGAAGCAC	GUGCUUCAGCCGCUACCCC	-2.2	-3.30 	-0.30 	1.00 	0.00 	5.00 	-45.3	26.80 	8.10 	1.00 	II	68.40 	32.90 	58.04 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3053	UYB79189	Takayuki Katoh	EGFP 	2315885245	CGGGGUAGCGGCUGAAGCA	UGCUUCAGCCGCUACCCCG	-2.1	-2.40 	-0.30 	-1.00 	-3.00 	5.00 	-45.5	28.50 	-8.10 	0.00 	III	68.40 	32.20 	58.61 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3054	UYB79189	Takayuki Katoh	EGFP 	2315885245	UCGGGGUAGCGGCUGAAGC	GCUUCAGCCGCUACCCCGA	-3.4	-2.40 	-0.30 	2.00 	3.00 	5.00 	-45.8	46.30 	12.10 	3.00 	II	68.40 	60.40 	76.26 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3055	UYB79189	Takayuki Katoh	EGFP 	2315885245	GUCGGGGUAGCGGCUGAAG	CUUCAGCCGCUACCCCGAC	-2.1	-2.20 	0.90 	0.00 	0.00 	5.00 	-44.6	30.60 	-2.40 	1.00 	II	68.40 	35.10 	60.09 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3056	UYB79189	Takayuki Katoh	EGFP 	2315885245	GGUCGGGGUAGCGGCUGAA	UUCAGCCGCUACCCCGACC	-0.9	-3.30 	0.90 	0.00 	-2.00 	5.00 	-45.8	19.80 	-6.10 	2.00 	III	68.40 	17.90 	36.62 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3057	UYB79189	Takayuki Katoh	EGFP 	2315885245	UGGUCGGGGUAGCGGCUGA	UCAGCCGCUACCCCGACCA	-2.4	-2.10 	0.90 	0.00 	-1.00 	5.00 	-47	38.80 	1.00 	5.00 	II	68.40 	39.90 	58.40 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3058	UYB79189	Takayuki Katoh	EGFP 	2315885245	GUGGUCGGGGUAGCGGCUG	CAGCCGCUACCCCGACCAC	-2.1	-2.20 	0.90 	1.00 	1.00 	5.00 	-46.8	25.50 	0.00 	2.00 	II	73.70 	42.20 	37.35 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3059	UYB79189	Takayuki Katoh	EGFP 	2315885245	UGUGGUCGGGGUAGCGGCU	AGCCGCUACCCCGACCACA	-2.1	-2.10 	0.90 	0.00 	2.00 	5.00 	-46.8	38.40 	-3.50 	3.00 	II	68.40 	48.70 	33.58 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3060	UYB79189	Takayuki Katoh	EGFP 	2315885245	AUGUGGUCGGGGUAGCGGC	GCCGCUACCCCGACCACAU	-3.4	-1.10 	0.90 	3.00 	4.00 	5.00 	-45.8	49.50 	7.40 	4.00 	Ib	68.40 	61.00 	44.70 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3061	UYB79189	Takayuki Katoh	EGFP 	2315885245	CAUGUGGUCGGGGUAGCGG	CCGCUACCCCGACCACAUG	-3.3	-2.10 	0.90 	0.00 	3.00 	5.00 	-44.5	42.60 	0.30 	3.00 	II	68.40 	49.50 	44.37 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3062	UYB79189	Takayuki Katoh	EGFP 	2315885245	UCAUGUGGUCGGGGUAGCG	CGCUACCCCGACCACAUGA	-2.4	-2.40 	1.20 	-1.00 	4.00 	5.00 	-43.6	44.50 	0.00 	5.00 	Ib	63.20 	58.20 	40.68 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3063	UYB79189	Takayuki Katoh	EGFP 	2315885245	UUCAUGUGGUCGGGGUAGC	GCUACCCCGACCACAUGAA	-3.4	-0.90 	2.80 	1.00 	3.00 	5.00 	-42.1	56.00 	5.10 	6.00 	Ia	57.90 	63.00 	44.75 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3064	UYB79189	Takayuki Katoh	EGFP 	2315885245	CUUCAUGUGGUCGGGGUAG	CUACCCCGACCACAUGAAG	-2.1	-2.10 	2.80 	0.00 	0.00 	5.00 	-40.8	43.60 	-1.70 	4.00 	II	57.90 	44.00 	39.67 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3065	UYB79189	Takayuki Katoh	EGFP 	2315885245	GCUUCAUGUGGUCGGGGUA	UACCCCGACCACAUGAAGC	-1.3	-3.40 	2.80 	0.00 	-2.00 	5.00 	-42.1	46.20 	1.70 	2.00 	II	57.90 	22.30 	30.87 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3066	UYB79189	Takayuki Katoh	EGFP 	2315885245	UGCUUCAUGUGGUCGGGGU	ACCCCGACCACAUGAAGCA	-2.2	-2.10 	2.80 	1.00 	1.00 	5.00 	-42.9	65.00 	-4.00 	5.00 	II	57.90 	50.40 	62.79 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3067	UYB79189	Takayuki Katoh	EGFP 	2315885245	CUGCUUCAUGUGGUCGGGG	CCCCGACCACAUGAAGCAG	-3.3	-2.10 	2.80 	0.00 	2.00 	5.00 	-42.8	43.80 	0.30 	1.00 	II	63.20 	48.80 	32.70 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3068	UYB79189	Takayuki Katoh	EGFP 	2315885245	GCUGCUUCAUGUGGUCGGG	CCCGACCACAUGAAGCAGC	-3.3	-3.40 	2.80 	0.00 	2.00 	4.00 	-42.9	46.10 	3.00 	1.00 	II	63.20 	35.00 	40.48 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3069	UYB79189	Takayuki Katoh	EGFP 	2315885245	UGCUGCUUCAUGUGGUCGG	CCGACCACAUGAAGCAGCA	-3.3	-2.10 	2.20 	1.00 	3.00 	3.00 	-41.7	66.30 	0.00 	5.00 	II	57.90 	62.10 	50.76 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3070	UYB79189	Takayuki Katoh	EGFP 	2315885245	GUGCUGCUUCAUGUGGUCG	CGACCACAUGAAGCAGCAC	-2.4	-2.20 	1.70 	1.00 	2.00 	2.00 	-40.6	58.60 	7.70 	2.00 	II	57.90 	48.30 	62.39 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3071	UYB79189	Takayuki Katoh	EGFP 	2315885245	CGUGCUGCUUCAUGUGGUC	GACCACAUGAAGCAGCACG	-2.4	-2.40 	1.70 	-2.00 	0.00 	2.00 	-40.6	47.50 	3.10 	1.00 	II	57.90 	39.10 	50.06 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3072	UYB79189	Takayuki Katoh	EGFP 	2315885245	UCGUGCUGCUUCAUGUGGU	ACCACAUGAAGCAGCACGA	-2.2	-2.40 	1.70 	2.00 	2.00 	2.00 	-40.6	61.30 	-6.60 	5.00 	II	52.60 	55.50 	70.72 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3073	UYB79189	Takayuki Katoh	EGFP 	2315885245	GUCGUGCUGCUUCAUGUGG	CCACAUGAAGCAGCACGAC	-3.3	-2.20 	1.70 	1.00 	1.00 	2.00 	-40.6	52.60 	5.40 	2.00 	II	57.90 	44.60 	67.17 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3074	UYB79189	Takayuki Katoh	EGFP 	2315885245	AGUCGUGCUGCUUCAUGUG	CACAUGAAGCAGCACGACU	-2.1	-2.10 	1.70 	2.00 	3.00 	2.00 	-39.4	59.40 	0.70 	4.00 	II	52.60 	52.80 	64.46 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3075	UYB79189	Takayuki Katoh	EGFP 	2315885245	AAGUCGUGCUGCUUCAUGU	ACAUGAAGCAGCACGACUU	-2.2	-0.90 	1.60 	3.00 	2.00 	2.00 	-38.2	77.40 	-4.00 	6.00 	II	47.40 	58.10 	82.71 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3076	UYB79189	Takayuki Katoh	EGFP 	2315885245	GAAGUCGUGCUGCUUCAUG	CAUGAAGCAGCACGACUUC	-2.1	-2.40 	-0.90 	1.00 	2.00 	2.00 	-38.4	56.80 	4.70 	4.00 	II	52.60 	48.90 	66.20 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3077	UYB79189	Takayuki Katoh	EGFP 	2315885245	AGAAGUCGUGCUGCUUCAU	AUGAAGCAGCACGACUUCU	-1.1	-2.10 	-2.10 	1.00 	1.00 	2.00 	-38.4	55.10 	-3.30 	3.00 	II	47.40 	42.50 	67.42 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3078	UYB79189	Takayuki Katoh	EGFP 	2315885245	AAGAAGUCGUGCUGCUUCA	UGAAGCAGCACGACUUCUU	-2.1	-0.90 	-2.10 	2.00 	0.00 	2.00 	-38.2	62.40 	-3.40 	6.00 	II	47.40 	51.80 	63.55 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3079	UYB79189	Takayuki Katoh	EGFP 	2315885245	GAAGAAGUCGUGCUGCUUC	GAAGCAGCACGACUUCUUC	-2.4	-2.40 	-2.10 	1.00 	2.00 	2.00 	-38.5	54.60 	14.80 	4.00 	II	52.60 	51.90 	64.69 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3080	UYB79189	Takayuki Katoh	EGFP 	2315885245	UGAAGAAGUCGUGCUGCUU	AAGCAGCACGACUUCUUCA	-0.9	-2.10 	1.00 	0.00 	1.00 	2.00 	-38.2	57.90 	-1.00 	6.00 	II	47.40 	54.20 	50.99 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3081	UYB79189	Takayuki Katoh	EGFP 	2315885245	UUGAAGAAGUCGUGCUGCU	AGCAGCACGACUUCUUCAA	-2.1	-0.90 	1.00 	0.00 	2.00 	2.00 	-38.2	59.20 	-3.60 	7.00 	II	47.40 	61.60 	52.94 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3082	UYB79189	Takayuki Katoh	EGFP 	2315885245	CUUGAAGAAGUCGUGCUGC	GCAGCACGACUUCUUCAAG	-3.4	-2.10 	1.00 	-1.00 	2.00 	2.00 	-38.2	51.20 	8.10 	5.00 	II	52.60 	54.20 	63.47 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3083	UYB79189	Takayuki Katoh	EGFP 	2315885245	ACUUGAAGAAGUCGUGCUG	CAGCACGACUUCUUCAAGU	-2.1	-2.20 	0.40 	0.00 	3.00 	2.00 	-37	61.20 	5.40 	6.00 	Ia	47.40 	50.20 	77.79 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3084	UYB79189	Takayuki Katoh	EGFP 	2315885245	GACUUGAAGAAGUCGUGCU	AGCACGACUUCUUCAAGUC	-2.1	-2.40 	-2.40 	1.00 	0.00 	2.00 	-37.3	67.30 	-1.70 	4.00 	II	47.40 	46.60 	76.48 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3085	UYB79189	Takayuki Katoh	EGFP 	2315885245	GGACUUGAAGAAGUCGUGC	GCACGACUUCUUCAAGUCC	-3.4	-3.30 	-3.20 	1.00 	2.00 	2.00 	-38.5	53.70 	12.00 	3.00 	II	52.60 	48.60 	78.22 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3086	UYB79189	Takayuki Katoh	EGFP 	2315885245	CGGACUUGAAGAAGUCGUG	CACGACUUCUUCAAGUCCG	-2.1	-2.40 	-3.20 	-1.00 	-1.00 	3.00 	-37.5	53.50 	-4.60 	2.00 	II	52.60 	44.70 	75.76 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3087	UYB79189	Takayuki Katoh	EGFP 	2315885245	GCGGACUUGAAGAAGUCGU	ACGACUUCUUCAAGUCCGC	-2.2	-3.40 	-3.20 	2.00 	-1.00 	4.00 	-38.8	49.10 	-1.60 	2.00 	III	52.60 	39.90 	52.06 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3088	UYB79189	Takayuki Katoh	EGFP 	2315885245	GGCGGACUUGAAGAAGUCG	CGACUUCUUCAAGUCCGCC	-2.4	-3.30 	-3.20 	0.00 	0.00 	5.00 	-39.9	35.80 	2.30 	-1.00 	II	57.90 	37.00 	44.01 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3089	UYB79189	Takayuki Katoh	EGFP 	2315885245	UGGCGGACUUGAAGAAGUC	GACUUCUUCAAGUCCGCCA	-2.4	-2.10 	-2.90 	0.00 	2.00 	5.00 	-39.6	43.70 	4.80 	3.00 	II	52.60 	56.90 	56.78 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3090	UYB79189	Takayuki Katoh	EGFP 	2315885245	AUGGCGGACUUGAAGAAGU	ACUUCUUCAAGUCCGCCAU	-2.2	-1.10 	0.70 	2.00 	1.00 	5.00 	-38.3	50.90 	-6.60 	4.00 	II	47.40 	56.40 	58.93 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3091	UYB79189	Takayuki Katoh	EGFP 	2315885245	CAUGGCGGACUUGAAGAAG	CUUCUUCAAGUCCGCCAUG	-2.1	-2.10 	1.90 	-1.00 	0.00 	5.00 	-38.2	44.40 	1.00 	3.00 	II	52.60 	42.70 	51.38 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3092	UYB79189	Takayuki Katoh	EGFP 	2315885245	GCAUGGCGGACUUGAAGAA	UUCUUCAAGUCCGCCAUGC	-0.9	-3.40 	2.00 	0.00 	-2.00 	5.00 	-39.5	38.00 	-3.10 	3.00 	III	52.60 	20.70 	31.18 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3093	UYB79189	Takayuki Katoh	EGFP 	2315885245	GGCAUGGCGGACUUGAAGA	UCUUCAAGUCCGCCAUGCC	-2.4	-3.30 	1.20 	1.00 	-2.00 	5.00 	-41.9	50.20 	-1.50 	2.00 	III	57.90 	33.10 	43.94 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3094	UYB79189	Takayuki Katoh	EGFP 	2315885245	GGGCAUGGCGGACUUGAAG	CUUCAAGUCCGCCAUGCCC	-2.1	-3.30 	1.20 	2.00 	0.00 	5.00 	-42.8	40.90 	7.40 	1.00 	II	63.20 	34.50 	51.05 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3095	UYB79189	Takayuki Katoh	EGFP 	2315885245	CGGGCAUGGCGGACUUGAA	UUCAAGUCCGCCAUGCCCG	-0.9	-2.40 	1.20 	1.00 	-4.00 	5.00 	-43.1	33.80 	-8.30 	0.00 	III	63.20 	21.60 	37.37 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3096	UYB79189	Takayuki Katoh	EGFP 	2315885245	UCGGGCAUGGCGGACUUGA	UCAAGUCCGCCAUGCCCGA	-2.4	-2.40 	1.20 	1.00 	-1.00 	5.00 	-44.6	38.30 	-6.10 	4.00 	II	63.20 	48.30 	47.23 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3097	UYB79189	Takayuki Katoh	EGFP 	2315885245	UUCGGGCAUGGCGGACUUG	CAAGUCCGCCAUGCCCGAA	-2.1	-0.90 	1.20 	-1.00 	2.00 	5.00 	-43.1	37.80 	-2.40 	4.00 	II	63.20 	54.70 	48.80 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3098	UYB79189	Takayuki Katoh	EGFP 	2315885245	CUUCGGGCAUGGCGGACUU	AAGUCCGCCAUGCCCGAAG	-0.9	-2.10 	1.20 	-1.00 	-1.00 	5.00 	-43.1	34.60 	-3.60 	2.00 	III	63.20 	33.70 	40.83 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3099	UYB79189	Takayuki Katoh	EGFP 	2315885245	CCUUCGGGCAUGGCGGACU	AGUCCGCCAUGCCCGAAGG	-2.1	-3.30 	1.10 	0.00 	-2.00 	5.00 	-45.5	37.80 	-6.00 	3.00 	III	68.40 	38.90 	47.08 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3100	UYB79189	Takayuki Katoh	EGFP 	2315885245	GCCUUCGGGCAUGGCGGAC	GUCCGCCAUGCCCGAAGGC	-2.2	-3.40 	-2.10 	0.00 	0.00 	5.00 	-46.8	30.90 	12.70 	1.00 	II	73.70 	25.40 	86.60 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3101	UYB79189	Takayuki Katoh	EGFP 	2315885245	AGCCUUCGGGCAUGGCGGA	UCCGCCAUGCCCGAAGGCU	-2.4	-2.10 	-3.30 	2.00 	0.00 	5.00 	-46.7	29.80 	-6.10 	1.00 	II	68.40 	31.40 	46.09 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3102	UYB79189	Takayuki Katoh	EGFP 	2315885245	UAGCCUUCGGGCAUGGCGG	CCGCCAUGCCCGAAGGCUA	-3.3	-1.30 	-3.30 	3.00 	5.00 	5.00 	-45.6	58.20 	-2.60 	3.00 	Ib	68.40 	69.10 	67.66 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3103	UYB79189	Takayuki Katoh	EGFP 	2315885245	GUAGCCUUCGGGCAUGGCG	CGCCAUGCCCGAAGGCUAC	-2.4	-2.20 	-3.30 	2.00 	3.00 	5.00 	-44.5	50.30 	2.40 	1.00 	II	68.40 	51.50 	61.92 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3104	UYB79189	Takayuki Katoh	EGFP 	2315885245	CGUAGCCUUCGGGCAUGGC	GCCAUGCCCGAAGGCUACG	-3.4	-2.40 	-3.30 	-1.00 	1.00 	5.00 	-44.5	40.00 	5.40 	0.00 	II	68.40 	36.60 	67.60 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3105	UYB79189	Takayuki Katoh	EGFP 	2315885245	ACGUAGCCUUCGGGCAUGG	CCAUGCCCGAAGGCUACGU	-3.3	-2.20 	-3.30 	0.00 	2.00 	5.00 	-43.3	36.70 	0.40 	3.00 	II	63.20 	44.00 	55.84 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3106	UYB79189	Takayuki Katoh	EGFP 	2315885245	GACGUAGCCUUCGGGCAUG	CAUGCCCGAAGGCUACGUC	-2.1	-2.40 	-3.30 	0.00 	0.00 	5.00 	-42.4	33.00 	-2.40 	1.00 	II	63.20 	37.10 	37.33 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3107	UYB79189	Takayuki Katoh	EGFP 	2315885245	GGACGUAGCCUUCGGGCAU	AUGCCCGAAGGCUACGUCC	-1.1	-3.30 	-3.30 	1.00 	-1.00 	5.00 	-43.6	33.30 	1.50 	0.00 	III	63.20 	28.10 	17.64 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3108	UYB79189	Takayuki Katoh	EGFP 	2315885245	UGGACGUAGCCUUCGGGCA	UGCCCGAAGGCUACGUCCA	-2.1	-2.10 	-3.30 	2.00 	0.00 	5.00 	-44.6	55.40 	-3.10 	3.00 	II	63.20 	52.20 	53.02 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3109	UYB79189	Takayuki Katoh	EGFP 	2315885245	CUGGACGUAGCCUUCGGGC	GCCCGAAGGCUACGUCCAG	-3.4	-2.10 	-3.30 	-1.00 	2.00 	5.00 	-44.6	46.50 	5.70 	1.00 	II	68.40 	51.00 	39.42 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3110	UYB79189	Takayuki Katoh	EGFP 	2315885245	CCUGGACGUAGCCUUCGGG	CCCGAAGGCUACGUCCAGG	-3.3	-3.30 	-0.30 	-1.00 	2.00 	4.00 	-44.5	37.80 	0.40 	1.00 	II	68.40 	38.00 	44.19 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3111	UYB79189	Takayuki Katoh	EGFP 	2315885245	UCCUGGACGUAGCCUUCGG	CCGAAGGCUACGUCCAGGA	-3.3	-2.40 	-0.30 	1.00 	3.00 	3.00 	-43.6	52.70 	4.70 	4.00 	II	63.20 	55.70 	37.91 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3112	UYB79189	Takayuki Katoh	EGFP 	2315885245	CUCCUGGACGUAGCCUUCG	CGAAGGCUACGUCCAGGAG	-2.4	-2.10 	-0.30 	1.00 	0.00 	3.00 	-42.4	42.00 	-2.00 	3.00 	II	63.20 	53.10 	43.91 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3113	UYB79189	Takayuki Katoh	EGFP 	2315885245	GCUCCUGGACGUAGCCUUC	GAAGGCUACGUCCAGGAGC	-2.4	-3.40 	-0.30 	0.00 	0.00 	3.00 	-43.4	44.10 	7.80 	2.00 	II	63.20 	36.70 	38.30 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3114	UYB79189	Takayuki Katoh	EGFP 	2315885245	CGCUCCUGGACGUAGCCUU	AAGGCUACGUCCAGGAGCG	-0.9	-2.40 	-1.40 	1.00 	-3.00 	3.00 	-43.4	49.70 	-8.30 	1.00 	III	63.20 	35.70 	50.78 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3115	UYB79189	Takayuki Katoh	EGFP 	2315885245	GCGCUCCUGGACGUAGCCU	AGGCUACGUCCAGGAGCGC	-2.1	-3.40 	-1.40 	2.00 	0.00 	4.00 	-45.9	33.90 	-1.70 	-1.00 	III	68.40 	30.10 	43.17 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3116	UYB79189	Takayuki Katoh	EGFP 	2315885245	UGCGCUCCUGGACGUAGCC	GGCUACGUCCAGGAGCGCA	-3.3	-2.10 	-1.40 	-1.00 	3.00 	4.00 	-45.9	46.90 	9.80 	1.00 	II	68.40 	55.50 	68.67 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3117	UYB79189	Takayuki Katoh	EGFP 	2315885245	GUGCGCUCCUGGACGUAGC	GCUACGUCCAGGAGCGCAC	-3.4	-2.20 	-1.40 	3.00 	1.00 	4.00 	-44.8	45.30 	4.80 	0.00 	II	68.40 	45.60 	57.42 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3118	UYB79189	Takayuki Katoh	EGFP 	2315885245	GGUGCGCUCCUGGACGUAG	CUACGUCCAGGAGCGCACC	-2.1	-3.30 	-0.60 	1.00 	0.00 	4.00 	-44.7	34.40 	0.00 	1.00 	II	68.40 	32.70 	45.22 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3119	UYB79189	Takayuki Katoh	EGFP 	2315885245	UGGUGCGCUCCUGGACGUA	UACGUCCAGGAGCGCACCA	-1.3	-2.10 	-0.90 	-1.00 	-1.00 	4.00 	-44.7	36.30 	-3.10 	4.00 	II	63.20 	38.50 	37.43 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3120	UYB79189	Takayuki Katoh	EGFP 	2315885245	AUGGUGCGCUCCUGGACGU	ACGUCCAGGAGCGCACCAU	-2.2	-1.10 	-0.90 	1.00 	2.00 	4.00 	-44.5	41.20 	-8.70 	3.00 	II	63.20 	46.30 	67.79 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3121	UYB79189	Takayuki Katoh	EGFP 	2315885245	GAUGGUGCGCUCCUGGACG	CGUCCAGGAGCGCACCAUC	-2.4	-2.40 	-0.90 	1.00 	3.00 	4.00 	-44.7	44.10 	2.40 	2.00 	II	68.40 	49.80 	54.01 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3122	UYB79189	Takayuki Katoh	EGFP 	2315885245	AGAUGGUGCGCUCCUGGAC	GUCCAGGAGCGCACCAUCU	-2.2	-2.10 	-0.90 	3.00 	3.00 	4.00 	-44.4	52.00 	10.50 	4.00 	Ib	63.20 	51.10 	79.03 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3123	UYB79189	Takayuki Katoh	EGFP 	2315885245	AAGAUGGUGCGCUCCUGGA	UCCAGGAGCGCACCAUCUU	-2.4	-0.90 	-0.90 	2.00 	1.00 	4.00 	-43.1	55.10 	-6.10 	5.00 	II	57.90 	49.10 	68.25 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3124	UYB79189	Takayuki Katoh	EGFP 	2315885245	GAAGAUGGUGCGCUCCUGG	CCAGGAGCGCACCAUCUUC	-3.3	-2.40 	-0.90 	0.00 	3.00 	4.00 	-43.1	46.10 	5.10 	4.00 	II	63.20 	51.20 	56.42 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3125	UYB79189	Takayuki Katoh	EGFP 	2315885245	AGAAGAUGGUGCGCUCCUG	CAGGAGCGCACCAUCUUCU	-2.1	-2.10 	-1.70 	3.00 	3.00 	4.00 	-41.9	45.30 	-2.40 	3.00 	Ia	57.90 	50.90 	56.80 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3126	UYB79189	Takayuki Katoh	EGFP 	2315885245	AAGAAGAUGGUGCGCUCCU	AGGAGCGCACCAUCUUCUU	-2.1	-0.90 	-1.50 	1.00 	2.00 	4.00 	-40.7	50.10 	1.10 	5.00 	II	52.60 	56.90 	93.83 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3127	UYB79189	Takayuki Katoh	EGFP 	2315885245	GAAGAAGAUGGUGCGCUCC	GGAGCGCACCAUCUUCUUC	-3.3	-2.40 	-1.00 	0.00 	2.00 	4.00 	-41	46.90 	13.10 	3.00 	II	57.90 	51.60 	60.87 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3128	UYB79189	Takayuki Katoh	EGFP 	2315885245	UGAAGAAGAUGGUGCGCUC	GAGCGCACCAUCUUCUUCA	-2.4	-2.10 	0.90 	-1.00 	3.00 	4.00 	-39.8	54.70 	7.40 	6.00 	Ia	52.60 	58.70 	72.63 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3129	UYB79189	Takayuki Katoh	EGFP 	2315885245	UUGAAGAAGAUGGUGCGCU	AGCGCACCAUCUUCUUCAA	-2.1	-0.90 	3.40 	1.00 	3.00 	4.00 	-38.3	61.60 	1.10 	8.00 	II	47.40 	70.50 	74.80 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3130	UYB79189	Takayuki Katoh	EGFP 	2315885245	CUUGAAGAAGAUGGUGCGC	GCGCACCAUCUUCUUCAAG	-3.4	-2.10 	2.40 	-2.00 	2.00 	4.00 	-38.3	47.30 	13.40 	4.00 	II	52.60 	47.60 	49.89 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3131	UYB79189	Takayuki Katoh	EGFP 	2315885245	CCUUGAAGAAGAUGGUGCG	CGCACCAUCUUCUUCAAGG	-2.4	-3.30 	1.10 	-2.00 	1.00 	3.00 	-38.2	52.50 	-2.00 	4.00 	II	52.60 	43.90 	70.54 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3132	UYB79189	Takayuki Katoh	EGFP 	2315885245	UCCUUGAAGAAGAUGGUGC	GCACCAUCUUCUUCAAGGA	-3.4	-2.40 	0.20 	1.00 	3.00 	2.00 	-38.2	74.70 	9.40 	8.00 	Ib	47.40 	69.50 	79.17 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3133	UYB79189	Takayuki Katoh	EGFP 	2315885245	GUCCUUGAAGAAGAUGGUG	CACCAUCUUCUUCAAGGAC	-2.1	-2.20 	0.00 	1.00 	1.00 	2.00 	-37	52.60 	2.30 	3.00 	II	47.40 	45.90 	57.07 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3134	UYB79189	Takayuki Katoh	EGFP 	2315885245	CGUCCUUGAAGAAGAUGGU	ACCAUCUUCUUCAAGGACG	-2.2	-2.40 	0.00 	0.00 	-1.00 	2.00 	-37.3	53.60 	-8.60 	3.00 	III	47.40 	37.90 	60.43 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3135	UYB79189	Takayuki Katoh	EGFP 	2315885245	UCGUCCUUGAAGAAGAUGG	CCAUCUUCUUCAAGGACGA	-3.3	-2.40 	0.00 	2.00 	2.00 	2.00 	-37.5	77.70 	-0.30 	7.00 	II	47.40 	69.70 	82.71 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3136	UYB79189	Takayuki Katoh	EGFP 	2315885245	GUCGUCCUUGAAGAAGAUG	CAUCUUCUUCAAGGACGAC	-2.1	-2.20 	0.00 	0.00 	0.00 	2.00 	-36.4	52.60 	2.30 	2.00 	II	47.40 	43.70 	40.19 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3137	UYB79189	Takayuki Katoh	EGFP 	2315885245	CGUCGUCCUUGAAGAAGAU	AUCUUCUUCAAGGACGACG	-1.1	-2.40 	0.00 	-1.00 	-2.00 	2.00 	-36.7	40.80 	-8.60 	1.00 	III	47.40 	25.70 	37.67 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3138	UYB79189	Takayuki Katoh	EGFP 	2315885245	CCGUCGUCCUUGAAGAAGA	UCUUCUUCAAGGACGACGG	-2.4	-3.30 	0.30 	1.00 	-4.00 	3.00 	-38.9	47.90 	-8.30 	2.00 	III	52.60 	37.30 	29.21 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3139	UYB79189	Takayuki Katoh	EGFP 	2315885245	GCCGUCGUCCUUGAAGAAG	CUUCUUCAAGGACGACGGC	-2.1	-3.40 	0.30 	1.00 	-1.00 	4.00 	-39.9	42.10 	3.00 	1.00 	II	57.90 	34.10 	31.41 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3140	UYB79189	Takayuki Katoh	EGFP 	2315885245	UGCCGUCGUCCUUGAAGAA	UUCUUCAAGGACGACGGCA	-0.9	-2.10 	0.30 	0.00 	-1.00 	4.00 	-39.9	47.70 	-3.10 	3.00 	II	52.60 	35.40 	44.72 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3141	UYB79189	Takayuki Katoh	EGFP 	2315885245	UUGCCGUCGUCCUUGAAGA	UCUUCAAGGACGACGGCAA	-2.4	-0.90 	0.50 	3.00 	1.00 	4.00 	-39.9	65.60 	-6.10 	5.00 	II	52.60 	58.70 	69.09 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3142	UYB79189	Takayuki Katoh	EGFP 	2315885245	GUUGCCGUCGUCCUUGAAG	CUUCAAGGACGACGGCAAC	-2.1	-2.20 	1.30 	1.00 	2.00 	4.00 	-39.7	58.40 	2.40 	2.00 	II	57.90 	45.20 	57.47 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3143	UYB79189	Takayuki Katoh	EGFP 	2315885245	AGUUGCCGUCGUCCUUGAA	UUCAAGGACGACGGCAACU	-0.9	-2.10 	1.30 	1.00 	0.00 	4.00 	-39.7	57.40 	1.70 	4.00 	II	52.60 	30.30 	53.96 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3144	UYB79189	Takayuki Katoh	EGFP 	2315885245	UAGUUGCCGUCGUCCUUGA	UCAAGGACGACGGCAACUA	-2.4	-1.30 	1.50 	1.00 	0.00 	4.00 	-40.1	65.10 	-6.10 	7.00 	II	52.60 	52.80 	72.14 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3145	UYB79189	Takayuki Katoh	EGFP 	2315885245	GUAGUUGCCGUCGUCCUUG	CAAGGACGACGGCAACUAC	-2.1	-2.20 	1.60 	1.00 	2.00 	4.00 	-39.9	53.10 	0.00 	4.00 	II	57.90 	55.60 	47.07 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3146	UYB79189	Takayuki Katoh	EGFP 	2315885245	UGUAGUUGCCGUCGUCCUU	AAGGACGACGGCAACUACA	-0.9	-2.10 	1.60 	1.00 	1.00 	4.00 	-39.9	65.10 	1.50 	6.00 	II	52.60 	53.80 	63.40 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3147	UYB79189	Takayuki Katoh	EGFP 	2315885245	UUGUAGUUGCCGUCGUCCU	AGGACGACGGCAACUACAA	-2.1	-0.90 	1.90 	2.00 	2.00 	4.00 	-39.9	69.80 	-3.60 	7.00 	II	52.60 	66.00 	62.52 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3148	UYB79189	Takayuki Katoh	EGFP 	2315885245	CUUGUAGUUGCCGUCGUCC	GGACGACGGCAACUACAAG	-3.3	-2.10 	3.10 	-1.00 	2.00 	4.00 	-39.9	56.80 	3.00 	4.00 	II	57.90 	57.90 	53.23 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3149	UYB79189	Takayuki Katoh	EGFP 	2315885245	UCUUGUAGUUGCCGUCGUC	GACGACGGCAACUACAAGA	-2.4	-2.40 	2.30 	-1.00 	3.00 	4.00 	-39	61.20 	7.50 	6.00 	Ia	52.60 	57.60 	57.85 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3150	UYB79189	Takayuki Katoh	EGFP 	2315885245	GUCUUGUAGUUGCCGUCGU	ACGACGGCAACUACAAGAC	-2.2	-2.20 	2.30 	2.00 	0.00 	4.00 	-38.8	56.90 	-1.60 	4.00 	II	52.60 	40.90 	44.83 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3151	UYB79189	Takayuki Katoh	EGFP 	2315885245	GGUCUUGUAGUUGCCGUCG	CGACGGCAACUACAAGACC	-2.4	-3.30 	1.90 	1.00 	1.00 	4.00 	-39.9	55.90 	3.00 	3.00 	II	57.90 	48.30 	80.45 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3152	UYB79189	Takayuki Katoh	EGFP 	2315885245	GGGUCUUGUAGUUGCCGUC	GACGGCAACUACAAGACCC	-2.4	-3.30 	1.10 	0.00 	0.00 	4.00 	-40.8	62.10 	10.40 	2.00 	II	57.90 	43.40 	70.03 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3153	UYB79189	Takayuki Katoh	EGFP 	2315885245	CGGGUCUUGUAGUUGCCGU	ACGGCAACUACAAGACCCG	-2.2	-2.40 	-0.20 	1.00 	-1.00 	4.00 	-40.8	57.20 	-1.30 	1.00 	III	57.90 	39.50 	69.33 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3154	UYB79189	Takayuki Katoh	EGFP 	2315885245	GCGGGUCUUGUAGUUGCCG	CGGCAACUACAAGACCCGC	-2.4	-3.40 	-0.10 	0.00 	2.00 	5.00 	-42	36.80 	2.30 	-1.00 	II	63.20 	41.90 	49.60 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3155	UYB79189	Takayuki Katoh	EGFP 	2315885245	CGCGGGUCUUGUAGUUGCC	GGCAACUACAAGACCCGCG	-3.3	-2.40 	0.20 	-1.00 	0.00 	6.00 	-42	42.40 	5.80 	0.00 	II	63.20 	41.00 	50.65 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3156	UYB79189	Takayuki Katoh	EGFP 	2315885245	GCGCGGGUCUUGUAGUUGC	GCAACUACAAGACCCGCGC	-3.4	-3.40 	0.20 	2.00 	0.00 	7.00 	-42.1	40.50 	7.40 	1.00 	II	63.20 	40.60 	47.84 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3157	UYB79189	Takayuki Katoh	EGFP 	2315885245	GGCGCGGGUCUUGUAGUUG	CAACUACAAGACCCGCGCC	-2.1	-3.30 	2.30 	0.00 	0.00 	8.00 	-42	39.00 	5.40 	1.00 	II	63.20 	35.10 	53.41 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3158	UYB79189	Takayuki Katoh	EGFP 	2315885245	CGGCGCGGGUCUUGUAGUU	AACUACAAGACCCGCGCCG	-0.9	-2.40 	2.30 	0.00 	-3.00 	9.00 	-42.3	32.20 	-5.30 	0.00 	III	63.20 	24.20 	34.59 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3159	UYB79189	Takayuki Katoh	EGFP 	2315885245	UCGGCGCGGGUCUUGUAGU	ACUACAAGACCCGCGCCGA	-2.2	-2.40 	1.90 	1.00 	1.00 	9.00 	-43.8	46.70 	-4.00 	2.00 	II	63.20 	49.50 	54.04 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3160	UYB79189	Takayuki Katoh	EGFP 	2315885245	CUCGGCGCGGGUCUUGUAG	CUACAAGACCCGCGCCGAG	-2.1	-2.10 	1.90 	0.00 	0.00 	9.00 	-43.7	47.50 	5.80 	2.00 	II	68.40 	39.90 	74.80 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3161	UYB79189	Takayuki Katoh	EGFP 	2315885245	CCUCGGCGCGGGUCUUGUA	UACAAGACCCGCGCCGAGG	-1.3	-3.30 	0.10 	1.00 	-3.00 	9.00 	-44.9	30.70 	-5.80 	0.00 	III	68.40 	21.90 	52.18 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3162	UYB79189	Takayuki Katoh	EGFP 	2315885245	ACCUCGGCGCGGGUCUUGU	ACAAGACCCGCGCCGAGGU	-2.2	-2.20 	-0.80 	2.00 	1.00 	9.00 	-45.8	43.50 	-1.60 	4.00 	II	68.40 	39.40 	58.90 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3163	UYB79189	Takayuki Katoh	EGFP 	2315885245	CACCUCGGCGCGGGUCUUG	CAAGACCCGCGCCGAGGUG	-2.1	-2.10 	-1.50 	0.00 	-1.00 	9.00 	-45.7	30.10 	-4.40 	2.00 	II	73.70 	37.30 	44.87 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3164	UYB79189	Takayuki Katoh	EGFP 	2315885245	UCACCUCGGCGCGGGUCUU	AAGACCCGCGCCGAGGUGA	-0.9	-2.40 	-2.50 	1.00 	1.00 	9.00 	-46	33.80 	-6.30 	2.00 	II	68.40 	41.00 	47.57 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3165	UYB79189	Takayuki Katoh	EGFP 	2315885245	UUCACCUCGGCGCGGGUCU	AGACCCGCGCCGAGGUGAA	-2.1	-0.90 	-2.50 	1.00 	1.00 	9.00 	-46	54.50 	-3.90 	5.00 	II	68.40 	57.10 	79.32 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3166	UYB79189	Takayuki Katoh	EGFP 	2315885245	CUUCACCUCGGCGCGGGUC	GACCCGCGCCGAGGUGAAG	-2.4	-2.10 	-2.50 	1.00 	1.00 	9.00 	-46	38.40 	5.80 	1.00 	II	73.70 	42.40 	71.87 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3167	UYB79189	Takayuki Katoh	EGFP 	2315885245	ACUUCACCUCGGCGCGGGU	ACCCGCGCCGAGGUGAAGU	-2.2	-2.20 	-2.50 	0.00 	2.00 	9.00 	-45.8	38.20 	-1.60 	2.00 	II	68.40 	32.90 	57.45 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3168	UYB79189	Takayuki Katoh	EGFP 	2315885245	AACUUCACCUCGGCGCGGG	CCCGCGCCGAGGUGAAGUU	-3.3	-0.90 	-2.50 	2.00 	4.00 	9.00 	-44.5	49.80 	-2.40 	4.00 	Ia	68.40 	54.20 	54.95 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3169	UYB79189	Takayuki Katoh	EGFP 	2315885245	GAACUUCACCUCGGCGCGG	CCGCGCCGAGGUGAAGUUC	-3.3	-2.40 	-2.50 	1.00 	3.00 	8.00 	-43.6	32.40 	-2.40 	1.00 	II	68.40 	43.30 	28.13 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3170	UYB79189	Takayuki Katoh	EGFP 	2315885245	CGAACUUCACCUCGGCGCG	CGCGCCGAGGUGAAGUUCG	-2.4	-2.40 	-2.50 	-1.00 	1.00 	7.00 	-42.7	48.30 	1.10 	1.00 	II	68.40 	45.70 	76.60 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3171	UYB79189	Takayuki Katoh	EGFP 	2315885245	UCGAACUUCACCUCGGCGC	GCGCCGAGGUGAAGUUCGA	-3.4	-2.40 	-2.50 	2.00 	3.00 	6.00 	-42.7	65.50 	5.40 	5.00 	Ib	63.20 	69.00 	87.44 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3172	UYB79189	Takayuki Katoh	EGFP 	2315885245	CUCGAACUUCACCUCGGCG	CGCCGAGGUGAAGUUCGAG	-2.4	-2.10 	-2.30 	-1.00 	2.00 	5.00 	-41.4	48.40 	5.40 	0.00 	II	63.20 	47.10 	66.60 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3173	UYB79189	Takayuki Katoh	EGFP 	2315885245	CCUCGAACUUCACCUCGGC	GCCGAGGUGAAGUUCGAGG	-3.4	-3.30 	-1.70 	0.00 	1.00 	4.00 	-42.3	37.10 	5.50 	0.00 	II	63.20 	40.30 	47.35 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3174	UYB79189	Takayuki Katoh	EGFP 	2315885245	CCCUCGAACUUCACCUCGG	CCGAGGUGAAGUUCGAGGG	-3.3	-3.30 	-1.70 	0.00 	0.00 	3.00 	-42.2	43.80 	-6.90 	0.00 	II	63.20 	44.40 	65.11 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3175	UYB79189	Takayuki Katoh	EGFP 	2315885245	GCCCUCGAACUUCACCUCG	CGAGGUGAAGUUCGAGGGC	-2.4	-3.40 	-1.40 	1.00 	0.00 	4.00 	-42.3	44.70 	5.40 	1.00 	II	63.20 	42.00 	40.11 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3176	UYB79189	Takayuki Katoh	EGFP 	2315885245	CGCCCUCGAACUUCACCUC	GAGGUGAAGUUCGAGGGCG	-2.4	-2.40 	-1.00 	0.00 	-1.00 	5.00 	-42.3	50.60 	6.10 	-1.00 	II	63.20 	39.70 	58.14 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3177	UYB79189	Takayuki Katoh	EGFP 	2315885245	UCGCCCUCGAACUUCACCU	AGGUGAAGUUCGAGGGCGA	-2.1	-2.40 	-1.00 	3.00 	2.00 	5.00 	-42.3	68.30 	-1.70 	3.00 	II	57.90 	63.60 	76.05 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3178	UYB79189	Takayuki Katoh	EGFP 	2315885245	GUCGCCCUCGAACUUCACC	GGUGAAGUUCGAGGGCGAC	-3.3	-2.20 	-1.00 	1.00 	2.00 	5.00 	-42.4	56.30 	14.40 	-1.00 	II	63.20 	47.70 	68.14 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3179	UYB79189	Takayuki Katoh	EGFP 	2315885245	UGUCGCCCUCGAACUUCAC	GUGAAGUUCGAGGGCGACA	-2.2	-2.10 	-1.00 	1.00 	3.00 	5.00 	-41.2	53.70 	4.80 	2.00 	II	57.90 	52.80 	68.96 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3180	UYB79189	Takayuki Katoh	EGFP 	2315885245	GUGUCGCCCUCGAACUUCA	UGAAGUUCGAGGGCGACAC	-2.1	-2.20 	-1.00 	1.00 	-2.00 	5.00 	-41.2	47.90 	-8.70 	1.00 	III	57.90 	36.50 	66.49 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3181	UYB79189	Takayuki Katoh	EGFP 	2315885245	GGUGUCGCCCUCGAACUUC	GAAGUUCGAGGGCGACACC	-2.4	-3.30 	-1.00 	1.00 	0.00 	5.00 	-42.4	40.40 	5.10 	2.00 	II	63.20 	42.40 	51.84 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3182	UYB79189	Takayuki Katoh	EGFP 	2315885245	GGGUGUCGCCCUCGAACUU	AAGUUCGAGGGCGACACCC	-0.9	-3.30 	-2.30 	0.00 	-2.00 	5.00 	-43.3	36.00 	-0.90 	-1.00 	III	63.20 	24.10 	38.57 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3183	UYB79189	Takayuki Katoh	EGFP 	2315885245	AGGGUGUCGCCCUCGAACU	AGUUCGAGGGCGACACCCU	-2.1	-2.10 	-4.10 	3.00 	0.00 	5.00 	-44.5	49.20 	-8.70 	2.00 	II	63.20 	51.60 	53.70 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3184	UYB79189	Takayuki Katoh	EGFP 	2315885245	CAGGGUGUCGCCCUCGAAC	GUUCGAGGGCGACACCCUG	-2.2	-2.10 	-4.80 	0.00 	0.00 	5.00 	-44.5	44.60 	5.40 	0.00 	II	68.40 	47.40 	58.99 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3185	UYB79189	Takayuki Katoh	EGFP 	2315885245	CCAGGGUGUCGCCCUCGAA	UUCGAGGGCGACACCCUGG	-0.9	-3.30 	-4.80 	0.00 	-3.00 	5.00 	-45.6	27.10 	-5.70 	0.00 	III	68.40 	25.60 	26.94 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3186	UYB79189	Takayuki Katoh	EGFP 	2315885245	ACCAGGGUGUCGCCCUCGA	UCGAGGGCGACACCCUGGU	-2.4	-2.20 	-4.80 	2.00 	0.00 	5.00 	-46.9	32.50 	-3.70 	2.00 	II	68.40 	35.90 	32.61 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3187	UYB79189	Takayuki Katoh	EGFP 	2315885245	CACCAGGGUGUCGCCCUCG	CGAGGGCGACACCCUGGUG	-2.4	-2.10 	-4.80 	0.00 	0.00 	5.00 	-46.6	28.20 	-1.70 	2.00 	II	73.70 	49.00 	25.29 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3188	UYB79189	Takayuki Katoh	EGFP 	2315885245	UCACCAGGGUGUCGCCCUC	GAGGGCGACACCCUGGUGA	-2.4	-2.40 	-4.80 	1.00 	3.00 	5.00 	-46.6	38.70 	12.80 	3.00 	II	68.40 	51.40 	39.28 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3189	UYB79189	Takayuki Katoh	EGFP 	2315885245	UUCACCAGGGUGUCGCCCU	AGGGCGACACCCUGGUGAA	-2.1	-0.90 	-4.40 	1.00 	2.00 	5.00 	-45.1	58.00 	-4.00 	4.00 	II	63.20 	63.90 	55.57 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3190	UYB79189	Takayuki Katoh	EGFP 	2315885245	GUUCACCAGGGUGUCGCCC	GGGCGACACCCUGGUGAAC	-3.3	-2.20 	-3.30 	2.00 	4.00 	5.00 	-45.2	44.80 	15.50 	1.00 	II	68.40 	46.70 	44.30 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3191	UYB79189	Takayuki Katoh	EGFP 	2315885245	GGUUCACCAGGGUGUCGCC	GGCGACACCCUGGUGAACC	-3.3	-3.30 	-3.20 	-1.00 	2.00 	4.00 	-45.2	44.00 	7.40 	0.00 	II	68.40 	33.20 	62.00 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3192	UYB79189	Takayuki Katoh	EGFP 	2315885245	CGGUUCACCAGGGUGUCGC	GCGACACCCUGGUGAACCG	-3.4	-2.40 	-3.20 	0.00 	1.00 	3.00 	-44.3	53.20 	7.70 	2.00 	II	68.40 	47.90 	80.95 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3193	UYB79189	Takayuki Katoh	EGFP 	2315885245	GCGGUUCACCAGGGUGUCG	CGACACCCUGGUGAACCGC	-2.4	-3.40 	-3.20 	0.00 	0.00 	4.00 	-44.3	34.70 	2.30 	0.00 	II	68.40 	34.80 	38.44 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3194	UYB79189	Takayuki Katoh	EGFP 	2315885245	UGCGGUUCACCAGGGUGUC	GACACCCUGGUGAACCGCA	-2.4	-2.10 	-3.20 	0.00 	2.00 	4.00 	-44	43.60 	5.10 	2.00 	II	63.20 	53.40 	51.35 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3195	UYB79189	Takayuki Katoh	EGFP 	2315885245	AUGCGGUUCACCAGGGUGU	ACACCCUGGUGAACCGCAU	-2.2	-1.10 	-3.20 	3.00 	1.00 	4.00 	-42.7	49.50 	-11.30 	4.00 	II	57.90 	55.10 	75.63 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3196	UYB79189	Takayuki Katoh	EGFP 	2315885245	GAUGCGGUUCACCAGGGUG	CACCCUGGUGAACCGCAUC	-2.1	-2.40 	-2.80 	0.00 	2.00 	4.00 	-42.9	46.30 	2.40 	1.00 	II	63.20 	44.20 	66.00 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3197	UYB79189	Takayuki Katoh	EGFP 	2315885245	CGAUGCGGUUCACCAGGGU	ACCCUGGUGAACCGCAUCG	-2.2	-2.40 	-2.80 	-1.00 	-1.00 	4.00 	-43.2	33.10 	-5.90 	1.00 	III	63.20 	31.40 	50.81 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3198	UYB79189	Takayuki Katoh	EGFP 	2315885245	UCGAUGCGGUUCACCAGGG	CCCUGGUGAACCGCAUCGA	-3.3	-2.40 	-2.80 	1.00 	3.00 	4.00 	-43.4	44.10 	-4.90 	3.00 	II	63.20 	59.10 	82.86 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3199	UYB79189	Takayuki Katoh	EGFP 	2315885245	CUCGAUGCGGUUCACCAGG	CCUGGUGAACCGCAUCGAG	-3.3	-2.10 	-2.80 	0.00 	0.00 	4.00 	-42.2	44.10 	6.10 	1.00 	II	63.20 	52.40 	64.13 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3200	UYB79189	Takayuki Katoh	EGFP 	2315885245	GCUCGAUGCGGUUCACCAG	CUGGUGAACCGCAUCGAGC	-2.1	-3.40 	-2.80 	3.00 	1.00 	4.00 	-42.3	44.20 	3.00 	0.00 	II	63.20 	34.90 	55.62 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3201	UYB79189	Takayuki Katoh	EGFP 	2315885245	AGCUCGAUGCGGUUCACCA	UGGUGAACCGCAUCGAGCU	-2.1	-2.10 	-2.80 	2.00 	1.00 	4.00 	-42.3	59.60 	-1.40 	2.00 	II	57.90 	46.90 	61.68 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3202	UYB79189	Takayuki Katoh	EGFP 	2315885245	CAGCUCGAUGCGGUUCACC	GGUGAACCGCAUCGAGCUG	-3.3	-2.10 	-2.80 	0.00 	1.00 	4.00 	-42.3	46.40 	5.40 	1.00 	II	63.20 	51.70 	57.74 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3203	UYB79189	Takayuki Katoh	EGFP 	2315885245	UCAGCUCGAUGCGGUUCAC	GUGAACCGCAUCGAGCUGA	-2.2	-2.40 	-0.80 	-1.00 	3.00 	4.00 	-41.4	48.10 	5.10 	3.00 	II	57.90 	48.10 	71.25 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3204	UYB79189	Takayuki Katoh	EGFP 	2315885245	UUCAGCUCGAUGCGGUUCA	UGAACCGCAUCGAGCUGAA	-2.1	-0.90 	-0.80 	1.00 	0.00 	4.00 	-40.1	64.10 	-1.40 	8.00 	II	52.60 	59.90 	77.65 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3205	UYB79189	Takayuki Katoh	EGFP 	2315885245	CUUCAGCUCGAUGCGGUUC	GAACCGCAUCGAGCUGAAG	-2.4	-2.10 	-0.80 	1.00 	0.00 	4.00 	-40.1	55.60 	13.40 	3.00 	II	57.90 	48.70 	69.41 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3206	UYB79189	Takayuki Katoh	EGFP 	2315885245	CCUUCAGCUCGAUGCGGUU	AACCGCAUCGAGCUGAAGG	-0.9	-3.30 	-0.80 	-2.00 	-2.00 	4.00 	-41	43.30 	-6.00 	2.00 	III	57.90 	28.50 	52.52 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3207	UYB79189	Takayuki Katoh	EGFP 	2315885245	CCCUUCAGCUCGAUGCGGU	ACCGCAUCGAGCUGAAGGG	-2.2	-3.30 	-0.80 	0.00 	-1.00 	4.00 	-43.4	45.20 	-8.60 	2.00 	III	63.20 	34.10 	70.09 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3208	UYB79189	Takayuki Katoh	EGFP 	2315885245	GCCCUUCAGCUCGAUGCGG	CCGCAUCGAGCUGAAGGGC	-3.3	-3.40 	-0.80 	2.00 	1.00 	4.00 	-44.6	29.50 	-2.40 	0.00 	II	68.40 	34.30 	37.51 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3209	UYB79189	Takayuki Katoh	EGFP 	2315885245	UGCCCUUCAGCUCGAUGCG	CGCAUCGAGCUGAAGGGCA	-2.4	-2.10 	-2.10 	1.00 	3.00 	4.00 	-43.4	56.90 	3.10 	2.00 	II	63.20 	57.20 	80.91 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3210	UYB79189	Takayuki Katoh	EGFP 	2315885245	AUGCCCUUCAGCUCGAUGC	GCAUCGAGCUGAAGGGCAU	-3.4	-1.10 	-2.10 	4.00 	3.00 	4.00 	-42.1	75.60 	5.10 	4.00 	II	57.90 	68.20 	83.65 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3211	UYB79189	Takayuki Katoh	EGFP 	2315885245	GAUGCCCUUCAGCUCGAUG	CAUCGAGCUGAAGGGCAUC	-2.1	-2.40 	-2.10 	0.00 	2.00 	4.00 	-41.1	59.80 	7.00 	0.00 	II	57.90 	42.70 	72.67 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3212	UYB79189	Takayuki Katoh	EGFP 	2315885245	CGAUGCCCUUCAGCUCGAU	AUCGAGCUGAAGGGCAUCG	-1.1	-2.40 	-2.10 	-1.00 	-2.00 	4.00 	-41.4	36.80 	-8.30 	0.00 	III	57.90 	25.10 	46.70 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3213	UYB79189	Takayuki Katoh	EGFP 	2315885245	UCGAUGCCCUUCAGCUCGA	UCGAGCUGAAGGGCAUCGA	-2.4	-2.40 	-2.10 	0.00 	0.00 	4.00 	-42.7	43.20 	-8.70 	3.00 	II	57.90 	47.10 	52.02 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3214	UYB79189	Takayuki Katoh	EGFP 	2315885245	GUCGAUGCCCUUCAGCUCG	CGAGCUGAAGGGCAUCGAC	-2.4	-2.20 	-2.10 	1.00 	1.00 	4.00 	-42.5	50.40 	8.10 	2.00 	II	63.20 	52.40 	65.53 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3215	UYB79189	Takayuki Katoh	EGFP 	2315885245	AGUCGAUGCCCUUCAGCUC	GAGCUGAAGGGCAUCGACU	-2.4	-2.10 	-2.10 	4.00 	3.00 	4.00 	-42.2	54.90 	8.10 	2.00 	Ib	57.90 	52.60 	60.50 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3216	UYB79189	Takayuki Katoh	EGFP 	2315885245	AAGUCGAUGCCCUUCAGCU	AGCUGAAGGGCAUCGACUU	-2.1	-0.90 	-2.10 	2.00 	3.00 	4.00 	-40.7	67.10 	-6.30 	4.00 	II	52.60 	59.20 	80.01 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3217	UYB79189	Takayuki Katoh	EGFP 	2315885245	GAAGUCGAUGCCCUUCAGC	GCUGAAGGGCAUCGACUUC	-3.4	-2.40 	-2.20 	0.00 	3.00 	4.00 	-41	53.40 	7.40 	2.00 	II	57.90 	52.00 	66.55 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3218	UYB79189	Takayuki Katoh	EGFP 	2315885245	UGAAGUCGAUGCCCUUCAG	CUGAAGGGCAUCGACUUCA	-2.1	-2.10 	-3.90 	0.00 	3.00 	4.00 	-39.7	61.50 	0.10 	4.00 	Ib	52.60 	53.80 	74.36 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3219	UYB79189	Takayuki Katoh	EGFP 	2315885245	UUGAAGUCGAUGCCCUUCA	UGAAGGGCAUCGACUUCAA	-2.1	-0.90 	-4.60 	2.00 	0.00 	4.00 	-38.5	70.20 	1.40 	8.00 	II	47.40 	68.90 	64.04 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3220	UYB79189	Takayuki Katoh	EGFP 	2315885245	CUUGAAGUCGAUGCCCUUC	GAAGGGCAUCGACUUCAAG	-2.4	-2.10 	-3.90 	0.00 	0.00 	4.00 	-38.5	58.70 	13.40 	4.00 	II	52.60 	53.80 	59.47 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3221	UYB79189	Takayuki Katoh	EGFP 	2315885245	CCUUGAAGUCGAUGCCCUU	AAGGGCAUCGACUUCAAGG	-0.9	-3.30 	-0.40 	-2.00 	-2.00 	4.00 	-39.4	43.10 	-6.00 	3.00 	II	52.60 	32.70 	43.18 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3222	UYB79189	Takayuki Katoh	EGFP 	2315885245	UCCUUGAAGUCGAUGCCCU	AGGGCAUCGACUUCAAGGA	-2.1	-2.40 	-0.40 	1.00 	2.00 	4.00 	-40.9	58.50 	-6.60 	6.00 	II	52.60 	57.80 	79.95 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3223	UYB79189	Takayuki Katoh	EGFP 	2315885245	CUCCUUGAAGUCGAUGCCC	GGGCAUCGACUUCAAGGAG	-3.3	-2.10 	-0.20 	0.00 	1.00 	4.00 	-40.9	48.00 	3.10 	2.00 	II	57.90 	55.70 	58.23 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3224	UYB79189	Takayuki Katoh	EGFP 	2315885245	CCUCCUUGAAGUCGAUGCC	GGCAUCGACUUCAAGGAGG	-3.3	-3.30 	-1.30 	0.00 	1.00 	3.00 	-40.9	58.10 	10.80 	1.00 	II	57.90 	46.00 	83.01 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3225	UYB79189	Takayuki Katoh	EGFP 	2315885245	UCCUCCUUGAAGUCGAUGC	GCAUCGACUUCAAGGAGGA	-3.4	-2.40 	-1.30 	2.00 	2.00 	2.00 	-40	83.40 	9.70 	6.00 	II	52.60 	67.50 	91.90 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3226	UYB79189	Takayuki Katoh	EGFP 	2315885245	GUCCUCCUUGAAGUCGAUG	CAUCGACUUCAAGGAGGAC	-2.1	-2.20 	-1.30 	1.00 	1.00 	2.00 	-38.8	56.20 	4.60 	1.00 	II	52.60 	43.70 	51.73 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3227	UYB79189	Takayuki Katoh	EGFP 	2315885245	CGUCCUCCUUGAAGUCGAU	AUCGACUUCAAGGAGGACG	-1.1	-2.40 	-1.30 	-1.00 	-2.00 	2.00 	-39.1	43.40 	-8.60 	0.00 	III	52.60 	24.30 	19.56 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3228	UYB79189	Takayuki Katoh	EGFP 	2315885245	CCGUCCUCCUUGAAGUCGA	UCGACUUCAAGGAGGACGG	-2.4	-3.30 	-1.30 	1.00 	-3.00 	3.00 	-41.3	47.20 	-8.30 	0.00 	III	57.90 	34.60 	44.20 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3229	UYB79189	Takayuki Katoh	EGFP 	2315885245	GCCGUCCUCCUUGAAGUCG	CGACUUCAAGGAGGACGGC	-2.4	-3.40 	-1.30 	1.00 	0.00 	4.00 	-42.3	43.10 	3.00 	0.00 	II	63.20 	38.70 	42.17 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3230	UYB79189	Takayuki Katoh	EGFP 	2315885245	UGCCGUCCUCCUUGAAGUC	GACUUCAAGGAGGACGGCA	-2.4	-2.10 	-1.30 	0.00 	2.00 	4.00 	-42	53.10 	8.10 	1.00 	II	57.90 	51.80 	53.68 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3231	UYB79189	Takayuki Katoh	EGFP 	2315885245	UUGCCGUCCUCCUUGAAGU	ACUUCAAGGAGGACGGCAA	-2.2	-0.90 	-1.30 	3.00 	2.00 	4.00 	-40.5	70.90 	-6.30 	4.00 	II	52.60 	64.20 	86.76 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3232	UYB79189	Takayuki Katoh	EGFP 	2315885245	GUUGCCGUCCUCCUUGAAG	CUUCAAGGAGGACGGCAAC	-2.1	-2.20 	-0.80 	1.00 	2.00 	4.00 	-40.5	58.70 	2.40 	2.00 	II	57.90 	44.10 	62.85 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3233	UYB79189	Takayuki Katoh	EGFP 	2315885245	UGUUGCCGUCCUCCUUGAA	UUCAAGGAGGACGGCAACA	-0.9	-2.10 	1.30 	0.00 	0.00 	4.00 	-40.5	60.40 	-0.70 	5.00 	II	52.60 	38.30 	68.20 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3234	UYB79189	Takayuki Katoh	EGFP 	2315885245	AUGUUGCCGUCCUCCUUGA	UCAAGGAGGACGGCAACAU	-2.4	-1.10 	1.60 	2.00 	0.00 	4.00 	-40.7	61.20 	-8.50 	6.00 	II	52.60 	47.00 	90.74 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3235	UYB79189	Takayuki Katoh	EGFP 	2315885245	GAUGUUGCCGUCCUCCUUG	CAAGGAGGACGGCAACAUC	-2.1	-2.40 	3.10 	1.00 	2.00 	4.00 	-40.7	60.10 	2.40 	4.00 	II	57.90 	53.90 	71.47 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3236	UYB79189	Takayuki Katoh	EGFP 	2315885245	GGAUGUUGCCGUCCUCCUU	AAGGAGGACGGCAACAUCC	-0.9	-3.30 	-0.40 	2.00 	-1.00 	4.00 	-41.9	55.20 	1.50 	2.00 	II	57.90 	36.50 	30.98 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3237	UYB79189	Takayuki Katoh	EGFP 	2315885245	AGGAUGUUGCCGUCCUCCU	AGGAGGACGGCAACAUCCU	-2.1	-2.10 	-2.20 	3.00 	1.00 	4.00 	-43.1	58.90 	-6.30 	3.00 	II	57.90 	53.70 	68.57 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3238	UYB79189	Takayuki Katoh	EGFP 	2315885245	CAGGAUGUUGCCGUCCUCC	GGAGGACGGCAACAUCCUG	-3.3	-2.10 	-2.90 	-1.00 	1.00 	4.00 	-43.1	49.50 	5.70 	2.00 	II	63.20 	57.60 	40.72 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3239	UYB79189	Takayuki Katoh	EGFP 	2315885245	CCAGGAUGUUGCCGUCCUC	GAGGACGGCAACAUCCUGG	-2.4	-3.30 	-2.90 	-1.00 	0.00 	4.00 	-43.1	33.70 	5.50 	0.00 	II	63.20 	38.10 	15.23 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3240	UYB79189	Takayuki Katoh	EGFP 	2315885245	CCCAGGAUGUUGCCGUCCU	AGGACGGCAACAUCCUGGG	-2.1	-3.30 	-2.50 	0.00 	-2.00 	4.00 	-44	38.70 	-3.60 	0.00 	III	63.20 	36.80 	80.61 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3241	UYB79189	Takayuki Katoh	EGFP 	2315885245	CCCCAGGAUGUUGCCGUCC	GGACGGCAACAUCCUGGGG	-3.3	-3.30 	-1.40 	0.00 	-1.00 	4.00 	-45.2	33.10 	11.10 	1.00 	II	68.40 	45.00 	81.66 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3242	UYB79189	Takayuki Katoh	EGFP 	2315885245	GCCCCAGGAUGUUGCCGUC	GACGGCAACAUCCUGGGGC	-2.4	-3.40 	-0.10 	0.00 	0.00 	5.00 	-45.3	33.80 	10.40 	0.00 	II	68.40 	26.50 	28.24 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3243	UYB79189	Takayuki Katoh	EGFP 	2315885245	UGCCCCAGGAUGUUGCCGU	ACGGCAACAUCCUGGGGCA	-2.2	-2.10 	-0.10 	2.00 	2.00 	5.00 	-45	55.00 	-1.60 	4.00 	II	63.20 	55.00 	84.16 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3244	UYB79189	Takayuki Katoh	EGFP 	2315885245	GUGCCCCAGGAUGUUGCCG	CGGCAACAUCCUGGGGCAC	-2.4	-2.20 	0.10 	2.00 	3.00 	5.00 	-45	45.20 	7.70 	0.00 	II	68.40 	42.90 	55.35 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3245	UYB79189	Takayuki Katoh	EGFP 	2315885245	UGUGCCCCAGGAUGUUGCC	GGCAACAUCCUGGGGCACA	-3.3	-2.10 	0.10 	-1.00 	4.00 	5.00 	-44.7	55.60 	7.40 	3.00 	II	63.20 	55.40 	68.58 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3246	UYB79189	Takayuki Katoh	EGFP 	2315885245	UUGUGCCCCAGGAUGUUGC	GCAACAUCCUGGGGCACAA	-3.4	-0.90 	0.10 	1.00 	4.00 	5.00 	-42.3	72.20 	7.10 	6.00 	II	57.90 	69.40 	84.43 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3247	UYB79189	Takayuki Katoh	EGFP 	2315885245	CUUGUGCCCCAGGAUGUUG	CAACAUCCUGGGGCACAAG	-2.1	-2.10 	0.70 	0.00 	0.00 	5.00 	-41	50.90 	0.30 	3.00 	II	57.90 	47.10 	76.97 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3248	UYB79189	Takayuki Katoh	EGFP 	2315885245	GCUUGUGCCCCAGGAUGUU	AACAUCCUGGGGCACAAGC	-0.9	-3.40 	0.70 	0.00 	-1.00 	5.00 	-42.3	34.20 	-6.30 	2.00 	III	57.90 	25.70 	39.47 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3249	UYB79189	Takayuki Katoh	EGFP 	2315885245	AGCUUGUGCCCCAGGAUGU	ACAUCCUGGGGCACAAGCU	-2.2	-2.10 	-1.30 	2.00 	0.00 	5.00 	-43.5	51.00 	-11.30 	4.00 	II	57.90 	45.90 	55.51 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3250	UYB79189	Takayuki Katoh	EGFP 	2315885245	CAGCUUGUGCCCCAGGAUG	CAUCCUGGGGCACAAGCUG	-2.1	-2.10 	-2.00 	1.00 	-1.00 	5.00 	-43.4	45.90 	-4.30 	1.00 	II	63.20 	47.30 	45.12 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3251	UYB79189	Takayuki Katoh	EGFP 	2315885245	CCAGCUUGUGCCCCAGGAU	AUCCUGGGGCACAAGCUGG	-1.1	-3.30 	-2.00 	0.00 	-2.00 	5.00 	-44.6	38.60 	-8.30 	0.00 	III	63.20 	32.90 	32.90 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3252	UYB79189	Takayuki Katoh	EGFP 	2315885245	UCCAGCUUGUGCCCCAGGA	UCCUGGGGCACAAGCUGGA	-2.4	-2.40 	-2.00 	2.00 	0.00 	5.00 	-45.9	51.70 	-3.70 	3.00 	II	63.20 	47.20 	64.64 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3253	UYB79189	Takayuki Katoh	EGFP 	2315885245	CUCCAGCUUGUGCCCCAGG	CCUGGGGCACAAGCUGGAG	-3.3	-2.10 	-2.00 	0.00 	0.00 	5.00 	-45.6	36.90 	3.10 	0.00 	II	68.40 	45.50 	26.71 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3254	UYB79189	Takayuki Katoh	EGFP 	2315885245	ACUCCAGCUUGUGCCCCAG	CUGGGGCACAAGCUGGAGU	-2.1	-2.20 	-2.00 	2.00 	3.00 	5.00 	-44.5	44.30 	3.00 	2.00 	II	63.20 	43.30 	90.87 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3255	UYB79189	Takayuki Katoh	EGFP 	2315885245	UACUCCAGCUUGUGCCCCA	UGGGGCACAAGCUGGAGUA	-2.1	-1.30 	-2.00 	0.00 	1.00 	5.00 	-43.7	58.00 	-3.80 	4.00 	II	57.90 	55.20 	64.89 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3256	UYB79189	Takayuki Katoh	EGFP 	2315885245	GUACUCCAGCUUGUGCCCC	GGGGCACAAGCUGGAGUAC	-3.3	-2.20 	-2.00 	2.00 	4.00 	5.00 	-43.8	47.70 	12.80 	1.00 	II	63.20 	50.50 	50.80 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3257	UYB79189	Takayuki Katoh	EGFP 	2315885245	UGUACUCCAGCUUGUGCCC	GGGCACAAGCUGGAGUACA	-3.3	-2.10 	-2.00 	-1.00 	4.00 	4.00 	-42.6	68.80 	8.10 	3.00 	Ib	57.90 	62.20 	88.84 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3258	UYB79189	Takayuki Katoh	EGFP 	2315885245	UUGUACUCCAGCUUGUGCC	GGCACAAGCUGGAGUACAA	-3.3	-0.90 	-1.60 	2.00 	5.00 	3.00 	-40.2	86.50 	10.10 	7.00 	Ia	52.60 	79.00 	89.95 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3259	UYB79189	Takayuki Katoh	EGFP 	2315885245	GUUGUACUCCAGCUUGUGC	GCACAAGCUGGAGUACAAC	-3.4	-2.20 	-0.50 	1.00 	3.00 	2.00 	-39.1	67.50 	14.40 	4.00 	II	52.60 	48.30 	85.91 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3260	UYB79189	Takayuki Katoh	EGFP 	2315885245	AGUUGUACUCCAGCUUGUG	CACAAGCUGGAGUACAACU	-2.1	-2.10 	0.70 	1.00 	3.00 	2.00 	-37.8	61.30 	-2.40 	5.00 	Ia	47.40 	54.10 	73.47 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3261	UYB79189	Takayuki Katoh	EGFP 	2315885245	UAGUUGUACUCCAGCUUGU	ACAAGCUGGAGUACAACUA	-2.2	-1.30 	0.70 	1.00 	1.00 	2.00 	-37	72.00 	-11.30 	8.00 	II	42.10 	63.30 	77.66 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3262	UYB79189	Takayuki Katoh	EGFP 	2315885245	GUAGUUGUACUCCAGCUUG	CAAGCUGGAGUACAACUAC	-2.1	-2.20 	0.70 	0.00 	1.00 	2.00 	-37	61.70 	0.10 	5.00 	II	47.40 	55.00 	77.60 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3263	UYB79189	Takayuki Katoh	EGFP 	2315885245	UGUAGUUGUACUCCAGCUU	AAGCUGGAGUACAACUACA	-0.9	-2.10 	0.00 	1.00 	1.00 	2.00 	-37	76.20 	-0.90 	7.00 	II	42.10 	62.10 	74.17 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3264	UYB79189	Takayuki Katoh	EGFP 	2315885245	UUGUAGUUGUACUCCAGCU	AGCUGGAGUACAACUACAA	-2.1	-0.90 	0.00 	2.00 	2.00 	2.00 	-37	79.90 	-1.30 	7.00 	II	42.10 	69.90 	81.59 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3265	UYB79189	Takayuki Katoh	EGFP 	2315885245	GUUGUAGUUGUACUCCAGC	GCUGGAGUACAACUACAAC	-3.4	-2.20 	0.00 	0.00 	3.00 	2.00 	-37.1	61.70 	12.10 	4.00 	II	47.40 	56.30 	69.99 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3266	UYB79189	Takayuki Katoh	EGFP 	2315885245	UGUUGUAGUUGUACUCCAG	CUGGAGUACAACUACAACA	-2.1	-2.10 	0.00 	0.00 	3.00 	2.00 	-35.8	76.30 	0.40 	6.00 	Ia	42.10 	61.80 	76.29 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3267	UYB79189	Takayuki Katoh	EGFP 	2315885245	CUGUUGUAGUUGUACUCCA	UGGAGUACAACUACAACAG	-2.1	-2.10 	0.00 	1.00 	-2.00 	2.00 	-35.8	64.60 	-5.80 	4.00 	II	42.10 	49.50 	56.26 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3268	UYB79189	Takayuki Katoh	EGFP 	2315885245	GCUGUUGUAGUUGUACUCC	GGAGUACAACUACAACAGC	-3.3	-3.40 	0.00 	0.00 	2.00 	2.00 	-37.1	64.90 	12.80 	4.00 	II	47.40 	52.30 	74.02 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3269	UYB79189	Takayuki Katoh	EGFP 	2315885245	GGCUGUUGUAGUUGUACUC	GAGUACAACUACAACAGCC	-2.4	-3.30 	0.00 	0.00 	0.00 	3.00 	-37.1	69.30 	10.40 	3.00 	II	47.40 	44.60 	85.32 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3270	UYB79189	Takayuki Katoh	EGFP 	2315885245	UGGCUGUUGUAGUUGUACU	AGUACAACUACAACAGCCA	-2.1	-2.10 	0.00 	3.00 	1.00 	3.00 	-36.8	79.10 	0.70 	5.00 	II	42.10 	61.10 	81.16 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3271	UYB79189	Takayuki Katoh	EGFP 	2315885245	GUGGCUGUUGUAGUUGUAC	GUACAACUACAACAGCCAC	-2.2	-2.20 	0.20 	0.00 	1.00 	3.00 	-36.9	61.20 	9.70 	3.00 	II	47.40 	49.20 	75.82 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3272	UYB79189	Takayuki Katoh	EGFP 	2315885245	UGUGGCUGUUGUAGUUGUA	UACAACUACAACAGCCACA	-1.3	-2.10 	2.30 	0.00 	0.00 	3.00 	-36.8	62.90 	-3.30 	5.00 	II	42.10 	45.90 	69.22 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3273	UYB79189	Takayuki Katoh	EGFP 	2315885245	UUGUGGCUGUUGUAGUUGU	ACAACUACAACAGCCACAA	-2.2	-0.90 	2.30 	1.00 	1.00 	3.00 	-36.4	70.80 	-4.00 	6.00 	II	42.10 	59.80 	70.00 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3274	UYB79189	Takayuki Katoh	EGFP 	2315885245	GUUGUGGCUGUUGUAGUUG	CAACUACAACAGCCACAAC	-2.1	-2.20 	2.30 	0.00 	2.00 	3.00 	-36.4	60.50 	5.40 	5.00 	II	47.40 	51.80 	68.17 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3275	UYB79189	Takayuki Katoh	EGFP 	2315885245	CGUUGUGGCUGUUGUAGUU	AACUACAACAGCCACAACG	-0.9	-2.40 	2.30 	-1.00 	-2.00 	3.00 	-36.7	60.20 	-3.00 	3.00 	III	47.40 	33.00 	68.52 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3276	UYB79189	Takayuki Katoh	EGFP 	2315885245	ACGUUGUGGCUGUUGUAGU	ACUACAACAGCCACAACGU	-2.2	-2.20 	2.20 	3.00 	1.00 	3.00 	-38	65.70 	-1.60 	5.00 	II	47.40 	50.50 	91.37 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3277	UYB79189	Takayuki Katoh	EGFP 	2315885245	GACGUUGUGGCUGUUGUAG	CUACAACAGCCACAACGUC	-2.1	-2.40 	2.10 	1.00 	1.00 	3.00 	-38.2	61.40 	3.00 	4.00 	II	52.60 	43.10 	85.53 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3278	UYB79189	Takayuki Katoh	EGFP 	2315885245	AGACGUUGUGGCUGUUGUA	UACAACAGCCACAACGUCU	-1.3	-2.10 	2.10 	2.00 	0.00 	3.00 	-38.2	54.00 	-6.10 	4.00 	II	47.40 	41.70 	79.31 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3279	UYB79189	Takayuki Katoh	EGFP 	2315885245	UAGACGUUGUGGCUGUUGU	ACAACAGCCACAACGUCUA	-2.2	-1.30 	2.10 	2.00 	2.00 	3.00 	-38.2	79.40 	0.80 	7.00 	II	47.40 	62.20 	91.91 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3280	UYB79189	Takayuki Katoh	EGFP 	2315885245	AUAGACGUUGUGGCUGUUG	CAACAGCCACAACGUCUAU	-2.1	-1.10 	2.10 	1.00 	3.00 	3.00 	-37.1	58.60 	2.70 	7.00 	Ib	47.40 	62.80 	78.33 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3281	UYB79189	Takayuki Katoh	EGFP 	2315885245	UAUAGACGUUGUGGCUGUU	AACAGCCACAACGUCUAUA	-0.9	-1.30 	2.10 	-1.00 	2.00 	3.00 	-36.3	61.60 	-1.00 	6.00 	II	42.10 	49.50 	73.12 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3282	UYB79189	Takayuki Katoh	EGFP 	2315885245	AUAUAGACGUUGUGGCUGU	ACAGCCACAACGUCUAUAU	-2.2	-1.10 	2.10 	1.00 	2.00 	3.00 	-36.5	62.30 	-1.30 	8.00 	II	42.10 	56.50 	74.34 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3283	UYB79189	Takayuki Katoh	EGFP 	2315885245	GAUAUAGACGUUGUGGCUG	CAGCCACAACGUCUAUAUC	-2.1	-2.40 	2.10 	1.00 	3.00 	3.00 	-36.7	62.60 	5.40 	5.00 	II	47.40 	51.10 	71.99 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3284	UYB79189	Takayuki Katoh	EGFP 	2315885245	UGAUAUAGACGUUGUGGCU	AGCCACAACGUCUAUAUCA	-2.1	-2.10 	2.10 	-1.00 	2.00 	3.00 	-36.7	73.20 	1.80 	7.00 	II	42.10 	58.40 	75.87 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3285	UYB79189	Takayuki Katoh	EGFP 	2315885245	AUGAUAUAGACGUUGUGGC	GCCACAACGUCUAUAUCAU	-3.4	-1.10 	2.40 	3.00 	5.00 	3.00 	-35.7	80.70 	7.40 	7.00 	Ia	42.10 	69.20 	96.68 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3286	UYB79189	Takayuki Katoh	EGFP 	2315885245	CAUGAUAUAGACGUUGUGG	CCACAACGUCUAUAUCAUG	-3.3	-2.10 	2.50 	-1.00 	2.00 	2.00 	-34.4	73.00 	3.00 	5.00 	II	42.10 	57.90 	87.94 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3287	UYB79189	Takayuki Katoh	EGFP 	2315885245	CCAUGAUAUAGACGUUGUG	CACAACGUCUAUAUCAUGG	-2.1	-3.30 	1.20 	-1.00 	0.00 	2.00 	-34.4	57.30 	0.40 	4.00 	II	42.10 	43.40 	64.59 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3288	UYB79189	Takayuki Katoh	EGFP 	2315885245	GCCAUGAUAUAGACGUUGU	ACAACGUCUAUAUCAUGGC	-2.2	-3.40 	-0.70 	0.00 	-2.00 	3.00 	-35.7	63.80 	-4.30 	4.00 	III	42.10 	37.50 	27.48 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3289	UYB79189	Takayuki Katoh	EGFP 	2315885245	GGCCAUGAUAUAGACGUUG	CAACGUCUAUAUCAUGGCC	-2.1	-3.30 	-1.50 	1.00 	-1.00 	4.00 	-36.8	47.30 	2.70 	3.00 	II	47.40 	45.00 	53.01 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3290	UYB79189	Takayuki Katoh	EGFP 	2315885245	CGGCCAUGAUAUAGACGUU	AACGUCUAUAUCAUGGCCG	-0.9	-2.40 	-1.50 	0.00 	-3.00 	5.00 	-37.1	46.00 	-3.20 	0.00 	III	47.40 	28.90 	33.60 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3291	UYB79189	Takayuki Katoh	EGFP 	2315885245	UCGGCCAUGAUAUAGACGU	ACGUCUAUAUCAUGGCCGA	-2.2	-2.40 	-1.50 	1.00 	1.00 	5.00 	-38.6	62.90 	-4.00 	4.00 	II	47.40 	62.80 	68.70 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3292	UYB79189	Takayuki Katoh	EGFP 	2315885245	GUCGGCCAUGAUAUAGACG	CGUCUAUAUCAUGGCCGAC	-2.4	-2.20 	-1.50 	0.00 	2.00 	5.00 	-38.6	54.90 	5.10 	0.00 	II	52.60 	47.50 	55.55 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3293	UYB79189	Takayuki Katoh	EGFP 	2315885245	UGUCGGCCAUGAUAUAGAC	GUCUAUAUCAUGGCCGACA	-2.2	-2.10 	-1.20 	1.00 	3.00 	5.00 	-38.3	60.60 	7.40 	3.00 	II	47.40 	53.90 	43.75 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3294	UYB79189	Takayuki Katoh	EGFP 	2315885245	UUGUCGGCCAUGAUAUAGA	UCUAUAUCAUGGCCGACAA	-2.4	-0.90 	0.50 	1.00 	1.00 	5.00 	-37	71.70 	-4.00 	7.00 	II	42.10 	64.10 	69.70 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3295	UYB79189	Takayuki Katoh	EGFP 	2315885245	CUUGUCGGCCAUGAUAUAG	CUAUAUCAUGGCCGACAAG	-2.1	-2.10 	0.50 	0.00 	0.00 	5.00 	-36.7	64.90 	3.30 	5.00 	II	47.40 	49.70 	60.50 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3296	UYB79189	Takayuki Katoh	EGFP 	2315885245	GCUUGUCGGCCAUGAUAUA	UAUAUCAUGGCCGACAAGC	-1.3	-3.40 	0.50 	0.00 	-3.00 	5.00 	-38	43.80 	-6.10 	2.00 	III	47.40 	20.90 	34.07 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3297	UYB79189	Takayuki Katoh	EGFP 	2315885245	UGCUUGUCGGCCAUGAUAU	AUAUCAUGGCCGACAAGCA	-1.1	-2.10 	-0.70 	2.00 	0.00 	5.00 	-38.8	70.90 	-8.90 	7.00 	II	47.40 	55.80 	85.53 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3298	UYB79189	Takayuki Katoh	EGFP 	2315885245	CUGCUUGUCGGCCAUGAUA	UAUCAUGGCCGACAAGCAG	-1.3	-2.10 	-0.70 	1.00 	-4.00 	5.00 	-39.8	54.10 	-5.70 	3.00 	III	52.60 	41.00 	61.07 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3299	UYB79189	Takayuki Katoh	EGFP 	2315885245	UCUGCUUGUCGGCCAUGAU	AUCAUGGCCGACAAGCAGA	-1.1	-2.40 	-0.70 	1.00 	1.00 	5.00 	-40.9	62.10 	-1.60 	5.00 	II	52.60 	48.50 	66.07 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3300	UYB79189	Takayuki Katoh	EGFP 	2315885245	UUCUGCUUGUCGGCCAUGA	UCAUGGCCGACAAGCAGAA	-2.4	-0.90 	-0.70 	2.00 	0.00 	5.00 	-40.7	63.90 	-6.10 	7.00 	II	52.60 	55.70 	72.90 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3301	UYB79189	Takayuki Katoh	EGFP 	2315885245	CUUCUGCUUGUCGGCCAUG	CAUGGCCGACAAGCAGAAG	-2.1	-2.10 	-0.70 	-1.00 	0.00 	5.00 	-40.4	42.20 	-4.40 	2.00 	II	57.90 	46.00 	38.02 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3302	UYB79189	Takayuki Katoh	EGFP 	2315885245	UCUUCUGCUUGUCGGCCAU	AUGGCCGACAAGCAGAAGA	-1.1	-2.40 	-0.70 	-1.00 	1.00 	5.00 	-40.7	64.40 	1.50 	6.00 	II	52.60 	46.00 	62.46 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3303	UYB79189	Takayuki Katoh	EGFP 	2315885245	UUCUUCUGCUUGUCGGCCA	UGGCCGACAAGCAGAAGAA	-2.1	-0.90 	-0.70 	2.00 	1.00 	5.00 	-40.5	72.40 	-3.80 	7.00 	II	52.60 	61.50 	82.16 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3304	UYB79189	Takayuki Katoh	EGFP 	2315885245	GUUCUUCUGCUUGUCGGCC	GGCCGACAAGCAGAAGAAC	-3.3	-2.20 	-0.70 	2.00 	4.00 	5.00 	-40.6	59.90 	12.80 	2.00 	II	57.90 	52.20 	63.25 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3305	UYB79189	Takayuki Katoh	EGFP 	2315885245	CGUUCUUCUGCUUGUCGGC	GCCGACAAGCAGAAGAACG	-3.4	-2.40 	-0.70 	-1.00 	1.00 	4.00 	-39.7	64.90 	6.10 	2.00 	II	57.90 	46.70 	90.76 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3306	UYB79189	Takayuki Katoh	EGFP 	2315885245	CCGUUCUUCUGCUUGUCGG	CCGACAAGCAGAAGAACGG	-3.3	-3.30 	0.00 	1.00 	1.00 	3.00 	-39.6	69.00 	-2.00 	2.00 	II	57.90 	47.00 	83.89 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3307	UYB79189	Takayuki Katoh	EGFP 	2315885245	GCCGUUCUUCUGCUUGUCG	CGACAAGCAGAAGAACGGC	-2.4	-3.40 	1.40 	0.00 	1.00 	4.00 	-39.7	56.50 	4.70 	1.00 	II	57.90 	42.20 	76.05 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3308	UYB79189	Takayuki Katoh	EGFP 	2315885245	UGCCGUUCUUCUGCUUGUC	GACAAGCAGAAGAACGGCA	-2.4	-2.10 	-0.30 	2.00 	2.00 	4.00 	-39.4	64.50 	8.10 	4.00 	II	52.60 	58.10 	84.26 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3309	UYB79189	Takayuki Katoh	EGFP 	2315885245	AUGCCGUUCUUCUGCUUGU	ACAAGCAGAAGAACGGCAU	-2.2	-1.10 	-0.30 	3.00 	1.00 	4.00 	-38.1	65.90 	-6.30 	5.00 	II	47.40 	54.90 	72.88 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3310	UYB79189	Takayuki Katoh	EGFP 	2315885245	GAUGCCGUUCUUCUGCUUG	CAAGCAGAAGAACGGCAUC	-2.1	-2.40 	-0.30 	0.00 	2.00 	4.00 	-38.3	67.30 	7.80 	4.00 	II	52.60 	48.80 	72.26 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3311	UYB79189	Takayuki Katoh	EGFP 	2315885245	UGAUGCCGUUCUUCUGCUU	AAGCAGAAGAACGGCAUCA	-0.9	-2.10 	-0.30 	0.00 	1.00 	4.00 	-38.3	66.50 	-3.30 	5.00 	II	47.40 	49.90 	78.94 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3312	UYB79189	Takayuki Katoh	EGFP 	2315885245	UUGAUGCCGUUCUUCUGCU	AGCAGAAGAACGGCAUCAA	-2.1	-0.90 	-0.30 	1.00 	3.00 	4.00 	-38.3	71.80 	-4.00 	6.00 	II	47.40 	65.20 	73.19 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3313	UYB79189	Takayuki Katoh	EGFP 	2315885245	CUUGAUGCCGUUCUUCUGC	GCAGAAGAACGGCAUCAAG	-3.4	-2.10 	-0.10 	0.00 	2.00 	4.00 	-38.3	67.90 	15.90 	5.00 	II	52.60 	59.80 	62.15 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3314	UYB79189	Takayuki Katoh	EGFP 	2315885245	CCUUGAUGCCGUUCUUCUG	CAGAAGAACGGCAUCAAGG	-2.1	-3.30 	0.80 	1.00 	0.00 	4.00 	-38.2	64.70 	1.00 	3.00 	II	52.60 	42.80 	73.29 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3315	UYB79189	Takayuki Katoh	EGFP 	2315885245	ACCUUGAUGCCGUUCUUCU	AGAAGAACGGCAUCAAGGU	-2.1	-2.20 	0.80 	2.00 	1.00 	4.00 	-38.3	71.50 	-4.00 	6.00 	II	47.40 	52.80 	82.46 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3316	UYB79189	Takayuki Katoh	EGFP 	2315885245	CACCUUGAUGCCGUUCUUC	GAAGAACGGCAUCAAGGUG	-2.4	-2.10 	0.20 	0.00 	0.00 	4.00 	-38.3	58.50 	3.00 	4.00 	II	52.60 	51.20 	68.43 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3317	UYB79189	Takayuki Katoh	EGFP 	2315885245	UCACCUUGAUGCCGUUCUU	AAGAACGGCAUCAAGGUGA	-0.9	-2.40 	-0.90 	1.00 	1.00 	4.00 	-38.3	62.50 	-3.90 	5.00 	II	47.40 	50.30 	70.62 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3318	UYB79189	Takayuki Katoh	EGFP 	2315885245	UUCACCUUGAUGCCGUUCU	AGAACGGCAUCAAGGUGAA	-2.1	-0.90 	-0.90 	2.00 	1.00 	4.00 	-38.3	82.90 	-1.60 	8.00 	II	47.40 	69.30 	91.47 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3319	UYB79189	Takayuki Katoh	EGFP 	2315885245	GUUCACCUUGAUGCCGUUC	GAACGGCAUCAAGGUGAAC	-2.4	-2.20 	-0.90 	1.00 	1.00 	4.00 	-38.4	61.30 	15.40 	4.00 	II	52.60 	46.90 	74.28 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3320	UYB79189	Takayuki Katoh	EGFP 	2315885245	AGUUCACCUUGAUGCCGUU	AACGGCAUCAAGGUGAACU	-0.9	-2.10 	-0.90 	0.00 	1.00 	4.00 	-38.1	56.70 	-4.00 	4.00 	II	47.40 	37.10 	59.25 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3321	UYB79189	Takayuki Katoh	EGFP 	2315885245	AAGUUCACCUUGAUGCCGU	ACGGCAUCAAGGUGAACUU	-2.2	-0.90 	-0.90 	2.00 	3.00 	4.00 	-38.1	67.70 	-4.20 	6.00 	II	47.40 	58.90 	87.02 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3322	UYB79189	Takayuki Katoh	EGFP 	2315885245	GAAGUUCACCUUGAUGCCG	CGGCAUCAAGGUGAACUUC	-2.4	-2.40 	-0.90 	1.00 	3.00 	4.00 	-38.3	54.00 	3.00 	3.00 	II	52.60 	53.40 	70.62 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3323	UYB79189	Takayuki Katoh	EGFP 	2315885245	UGAAGUUCACCUUGAUGCC	GGCAUCAAGGUGAACUUCA	-3.3	-2.10 	-0.90 	0.00 	4.00 	3.00 	-38	72.80 	8.10 	6.00 	Ia	47.40 	68.20 	94.06 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3324	UYB79189	Takayuki Katoh	EGFP 	2315885245	UUGAAGUUCACCUUGAUGC	GCAUCAAGGUGAACUUCAA	-3.4	-0.90 	-0.90 	2.00 	4.00 	2.00 	-35.6	91.40 	7.70 	9.00 	Ia	42.10 	83.90 	90.63 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3325	UYB79189	Takayuki Katoh	EGFP 	2315885245	CUUGAAGUUCACCUUGAUG	CAUCAAGGUGAACUUCAAG	-2.1	-2.10 	-0.70 	-1.00 	1.00 	2.00 	-34.3	67.60 	5.40 	4.00 	II	42.10 	51.90 	85.50 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3326	UYB79189	Takayuki Katoh	EGFP 	2315885245	UCUUGAAGUUCACCUUGAU	AUCAAGGUGAACUUCAAGA	-1.1	-2.40 	-0.40 	0.00 	1.00 	2.00 	-34.6	66.40 	-3.90 	6.00 	II	36.80 	47.80 	77.14 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3327	UYB79189	Takayuki Katoh	EGFP 	2315885245	AUCUUGAAGUUCACCUUGA	UCAAGGUGAACUUCAAGAU	-2.4	-1.10 	-0.40 	2.00 	0.00 	2.00 	-34.6	69.10 	-8.70 	7.00 	II	36.80 	55.40 	96.03 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3328	UYB79189	Takayuki Katoh	EGFP 	2315885245	GAUCUUGAAGUUCACCUUG	CAAGGUGAACUUCAAGAUC	-2.1	-2.40 	-0.40 	1.00 	1.00 	2.00 	-34.6	68.40 	5.40 	5.00 	II	42.10 	54.10 	93.71 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3329	UYB79189	Takayuki Katoh	EGFP 	2315885245	GGAUCUUGAAGUUCACCUU	AAGGUGAACUUCAAGAUCC	-0.9	-3.30 	-0.40 	1.00 	-1.00 	2.00 	-35.8	74.40 	-1.00 	4.00 	II	42.10 	42.50 	93.86 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3330	UYB79189	Takayuki Katoh	EGFP 	2315885245	CGGAUCUUGAAGUUCACCU	AGGUGAACUUCAAGAUCCG	-2.1	-2.40 	-0.10 	1.00 	-1.00 	3.00 	-37.3	75.10 	-1.30 	4.00 	III	47.40 	52.40 	93.27 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3331	UYB79189	Takayuki Katoh	EGFP 	2315885245	GCGGAUCUUGAAGUUCACC	GGUGAACUUCAAGAUCCGC	-3.3	-3.40 	0.30 	0.00 	1.00 	4.00 	-38.6	51.00 	14.70 	1.00 	II	52.60 	45.50 	72.60 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3332	UYB79189	Takayuki Katoh	EGFP 	2315885245	GGCGGAUCUUGAAGUUCAC	GUGAACUUCAAGAUCCGCC	-2.2	-3.30 	0.50 	0.00 	0.00 	5.00 	-38.6	41.70 	4.80 	1.00 	II	52.60 	31.50 	56.76 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3333	UYB79189	Takayuki Katoh	EGFP 	2315885245	UGGCGGAUCUUGAAGUUCA	UGAACUUCAAGAUCCGCCA	-2.1	-2.10 	1.10 	2.00 	-1.00 	5.00 	-38.5	55.00 	-6.30 	5.00 	II	47.40 	56.70 	78.09 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3334	UYB79189	Takayuki Katoh	EGFP 	2315885245	GUGGCGGAUCUUGAAGUUC	GAACUUCAAGAUCCGCCAC	-2.4	-2.20 	1.80 	0.00 	0.00 	5.00 	-38.6	46.70 	10.40 	3.00 	II	52.60 	47.80 	75.05 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3335	UYB79189	Takayuki Katoh	EGFP 	2315885245	UGUGGCGGAUCUUGAAGUU	AACUUCAAGAUCCGCCACA	-0.9	-2.10 	2.30 	-1.00 	1.00 	5.00 	-38.3	55.30 	-3.30 	5.00 	II	47.40 	46.40 	65.81 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3336	UYB79189	Takayuki Katoh	EGFP 	2315885245	UUGUGGCGGAUCUUGAAGU	ACUUCAAGAUCCGCCACAA	-2.2	-0.90 	2.30 	1.00 	2.00 	5.00 	-38.3	68.40 	-4.00 	6.00 	II	47.40 	64.20 	84.53 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3337	UYB79189	Takayuki Katoh	EGFP 	2315885245	GUUGUGGCGGAUCUUGAAG	CUUCAAGAUCCGCCACAAC	-2.1	-2.20 	2.80 	1.00 	2.00 	5.00 	-38.3	62.00 	10.10 	4.00 	II	52.60 	45.90 	69.02 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3338	UYB79189	Takayuki Katoh	EGFP 	2315885245	UGUUGUGGCGGAUCUUGAA	UUCAAGAUCCGCCACAACA	-0.9	-2.10 	4.80 	1.00 	0.00 	5.00 	-38.3	65.70 	-3.80 	6.00 	II	47.40 	47.00 	81.89 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3339	UYB79189	Takayuki Katoh	EGFP 	2315885245	AUGUUGUGGCGGAUCUUGA	UCAAGAUCCGCCACAACAU	-2.4	-1.10 	5.40 	3.00 	1.00 	5.00 	-38.5	67.80 	-4.00 	7.00 	II	47.40 	54.20 	80.01 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3340	UYB79189	Takayuki Katoh	EGFP 	2315885245	GAUGUUGUGGCGGAUCUUG	CAAGAUCCGCCACAACAUC	-2.1	-2.40 	2.70 	1.00 	1.00 	5.00 	-38.5	54.70 	-2.40 	5.00 	II	52.60 	49.00 	57.62 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3341	UYB79189	Takayuki Katoh	EGFP 	2315885245	CGAUGUUGUGGCGGAUCUU	AAGAUCCGCCACAACAUCG	-0.9	-2.40 	1.00 	-1.00 	-2.00 	5.00 	-38.8	44.30 	-8.30 	3.00 	II	52.60 	35.50 	62.21 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3342	UYB79189	Takayuki Katoh	EGFP 	2315885245	UCGAUGUUGUGGCGGAUCU	AGAUCCGCCACAACAUCGA	-2.1	-2.40 	1.00 	1.00 	0.00 	5.00 	-40.3	62.60 	-1.60 	7.00 	II	52.60 	56.10 	80.25 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3343	UYB79189	Takayuki Katoh	EGFP 	2315885245	CUCGAUGUUGUGGCGGAUC	GAUCCGCCACAACAUCGAG	-2.4	-2.10 	1.20 	-1.00 	-1.00 	5.00 	-40.3	46.80 	8.10 	2.00 	II	57.90 	50.60 	57.92 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3344	UYB79189	Takayuki Katoh	EGFP 	2315885245	CCUCGAUGUUGUGGCGGAU	AUCCGCCACAACAUCGAGG	-1.1	-3.30 	1.20 	0.00 	-2.00 	5.00 	-41.2	34.50 	-3.00 	1.00 	III	57.90 	22.80 	36.76 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3345	UYB79189	Takayuki Katoh	EGFP 	2315885245	UCCUCGAUGUUGUGGCGGA	UCCGCCACAACAUCGAGGA	-2.4	-2.40 	-0.60 	0.00 	0.00 	5.00 	-42.5	49.20 	-3.80 	4.00 	II	57.90 	43.70 	77.77 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3346	UYB79189	Takayuki Katoh	EGFP 	2315885245	GUCCUCGAUGUUGUGGCGG	CCGCCACAACAUCGAGGAC	-3.3	-2.20 	0.20 	1.00 	3.00 	5.00 	-42.3	47.10 	5.40 	2.00 	II	63.20 	46.50 	29.22 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3347	UYB79189	Takayuki Katoh	EGFP 	2315885245	CGUCCUCGAUGUUGUGGCG	CGCCACAACAUCGAGGACG	-2.4	-2.40 	0.40 	-1.00 	1.00 	4.00 	-41.4	50.10 	1.00 	0.00 	II	63.20 	35.10 	36.41 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3348	UYB79189	Takayuki Katoh	EGFP 	2315885245	CCGUCCUCGAUGUUGUGGC	GCCACAACAUCGAGGACGG	-3.4	-3.30 	0.40 	1.00 	1.00 	3.00 	-42.3	60.70 	7.70 	2.00 	II	63.20 	48.00 	73.44 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3349	UYB79189	Takayuki Katoh	EGFP 	2315885245	GCCGUCCUCGAUGUUGUGG	CCACAACAUCGAGGACGGC	-3.3	-3.40 	0.30 	1.00 	1.00 	4.00 	-42.3	53.10 	7.70 	1.00 	II	63.20 	36.60 	50.45 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3350	UYB79189	Takayuki Katoh	EGFP 	2315885245	UGCCGUCCUCGAUGUUGUG	CACAACAUCGAGGACGGCA	-2.1	-2.10 	0.30 	0.00 	2.00 	4.00 	-41.1	51.50 	0.00 	2.00 	II	57.90 	48.40 	42.56 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3351	UYB79189	Takayuki Katoh	EGFP 	2315885245	CUGCCGUCCUCGAUGUUGU	ACAACAUCGAGGACGGCAG	-2.2	-2.10 	0.30 	2.00 	-1.00 	4.00 	-41.1	55.20 	-8.60 	2.00 	III	57.90 	44.40 	49.76 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3352	UYB79189	Takayuki Katoh	EGFP 	2315885245	GCUGCCGUCCUCGAUGUUG	CAACAUCGAGGACGGCAGC	-2.1	-3.40 	0.30 	1.00 	0.00 	4.00 	-42.3	42.50 	-2.40 	2.00 	II	63.20 	38.60 	41.07 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3353	UYB79189	Takayuki Katoh	EGFP 	2315885245	CGCUGCCGUCCUCGAUGUU	AACAUCGAGGACGGCAGCG	-0.9	-2.40 	0.30 	-2.00 	-3.00 	4.00 	-42.6	35.30 	-2.90 	0.00 	III	63.20 	19.50 	22.07 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3354	UYB79189	Takayuki Katoh	EGFP 	2315885245	ACGCUGCCGUCCUCGAUGU	ACAUCGAGGACGGCAGCGU	-2.2	-2.20 	-0.30 	3.00 	0.00 	4.00 	-43.9	43.80 	-8.70 	3.00 	II	63.20 	41.00 	46.68 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3355	UYB79189	Takayuki Katoh	EGFP 	2315885245	CACGCUGCCGUCCUCGAUG	CAUCGAGGACGGCAGCGUG	-2.1	-2.10 	-1.00 	0.00 	0.00 	4.00 	-43.8	47.20 	0.40 	0.00 	II	68.40 	49.00 	55.56 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3356	UYB79189	Takayuki Katoh	EGFP 	2315885245	GCACGCUGCCGUCCUCGAU	AUCGAGGACGGCAGCGUGC	-1.1	-3.40 	-1.00 	3.00 	-1.00 	4.00 	-45.1	37.10 	1.50 	0.00 	III	68.40 	25.50 	29.90 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3357	UYB79189	Takayuki Katoh	EGFP 	2315885245	UGCACGCUGCCGUCCUCGA	UCGAGGACGGCAGCGUGCA	-2.4	-2.10 	-1.30 	1.00 	0.00 	4.00 	-46.1	46.70 	-6.10 	2.00 	II	68.40 	43.20 	37.45 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3358	UYB79189	Takayuki Katoh	EGFP 	2315885245	CUGCACGCUGCCGUCCUCG	CGAGGACGGCAGCGUGCAG	-2.4	-2.10 	-1.30 	0.00 	1.00 	4.00 	-45.8	36.90 	-1.70 	2.00 	II	73.70 	51.30 	27.54 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3359	UYB79189	Takayuki Katoh	EGFP 	2315885245	GCUGCACGCUGCCGUCCUC	GAGGACGGCAGCGUGCAGC	-2.4	-3.40 	-1.30 	0.00 	1.00 	4.00 	-46.8	28.00 	7.50 	-1.00 	II	73.70 	26.50 	20.11 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3360	UYB79189	Takayuki Katoh	EGFP 	2315885245	AGCUGCACGCUGCCGUCCU	AGGACGGCAGCGUGCAGCU	-2.1	-2.10 	-1.90 	2.00 	1.00 	4.00 	-46.5	42.80 	-1.60 	2.00 	II	68.40 	44.60 	26.23 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3361	UYB79189	Takayuki Katoh	EGFP 	2315885245	GAGCUGCACGCUGCCGUCC	GGACGGCAGCGUGCAGCUC	-3.3	-2.40 	-2.00 	2.00 	1.00 	4.00 	-46.8	37.80 	8.10 	1.00 	II	73.70 	45.80 	39.97 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3362	UYB79189	Takayuki Katoh	EGFP 	2315885245	CGAGCUGCACGCUGCCGUC	GACGGCAGCGUGCAGCUCG	-2.4	-2.40 	-2.00 	-2.00 	0.00 	4.00 	-45.9	34.70 	3.10 	0.00 	II	73.70 	39.50 	30.47 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3363	UYB79189	Takayuki Katoh	EGFP 	2315885245	GCGAGCUGCACGCUGCCGU	ACGGCAGCGUGCAGCUCGC	-2.2	-3.40 	-2.00 	2.00 	0.00 	4.00 	-46.9	37.60 	-1.60 	1.00 	III	73.70 	35.30 	31.53 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3364	UYB79189	Takayuki Katoh	EGFP 	2315885245	GGCGAGCUGCACGCUGCCG	CGGCAGCGUGCAGCUCGCC	-2.4	-3.30 	-2.40 	1.00 	1.00 	4.00 	-48	23.40 	2.70 	-1.00 	II	78.90 	33.00 	27.87 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3365	UYB79189	Takayuki Katoh	EGFP 	2315885245	CGGCGAGCUGCACGCUGCC	GGCAGCGUGCAGCUCGCCG	-3.3	-2.40 	-3.20 	-1.00 	0.00 	5.00 	-48	16.70 	5.50 	-1.00 	II	78.90 	36.50 	15.60 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3366	UYB79189	Takayuki Katoh	EGFP 	2315885245	UCGGCGAGCUGCACGCUGC	GCAGCGUGCAGCUCGCCGA	-3.4	-2.40 	-2.40 	1.00 	2.00 	5.00 	-47.1	42.00 	2.50 	3.00 	II	73.70 	59.90 	45.76 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3367	UYB79189	Takayuki Katoh	EGFP 	2315885245	GUCGGCGAGCUGCACGCUG	CAGCGUGCAGCUCGCCGAC	-2.1	-2.20 	-2.40 	1.00 	1.00 	5.00 	-45.9	25.70 	2.40 	0.00 	II	73.70 	40.30 	30.52 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3368	UYB79189	Takayuki Katoh	EGFP 	2315885245	GGUCGGCGAGCUGCACGCU	AGCGUGCAGCUCGCCGACC	-2.1	-3.30 	-2.40 	1.00 	0.00 	5.00 	-47.1	20.70 	-3.30 	-1.00 	III	73.70 	25.60 	36.25 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3369	UYB79189	Takayuki Katoh	EGFP 	2315885245	UGGUCGGCGAGCUGCACGC	GCGUGCAGCUCGCCGACCA	-3.4	-2.10 	-2.20 	0.00 	3.00 	5.00 	-47.1	47.40 	5.10 	4.00 	II	73.70 	60.40 	62.15 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3370	UYB79189	Takayuki Katoh	EGFP 	2315885245	GUGGUCGGCGAGCUGCACG	CGUGCAGCUCGCCGACCAC	-2.4	-2.20 	-0.10 	1.00 	2.00 	5.00 	-45.9	42.90 	7.00 	2.00 	II	73.70 	48.80 	54.46 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3371	UYB79189	Takayuki Katoh	EGFP 	2315885245	AGUGGUCGGCGAGCUGCAC	GUGCAGCUCGCCGACCACU	-2.2	-2.10 	-0.10 	2.00 	3.00 	5.00 	-45.6	34.60 	7.40 	2.00 	II	68.40 	42.10 	56.92 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3372	UYB79189	Takayuki Katoh	EGFP 	2315885245	UAGUGGUCGGCGAGCUGCA	UGCAGCUCGCCGACCACUA	-2.1	-1.30 	-0.10 	1.00 	1.00 	5.00 	-44.7	43.50 	-8.70 	5.00 	II	63.20 	54.90 	56.41 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3373	UYB79189	Takayuki Katoh	EGFP 	2315885245	GUAGUGGUCGGCGAGCUGC	GCAGCUCGCCGACCACUAC	-3.4	-2.20 	-0.10 	1.00 	2.00 	5.00 	-44.8	40.60 	5.10 	4.00 	II	68.40 	52.50 	51.22 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3374	UYB79189	Takayuki Katoh	EGFP 	2315885245	GGUAGUGGUCGGCGAGCUG	CAGCUCGCCGACCACUACC	-2.1	-3.30 	2.90 	-1.00 	1.00 	5.00 	-44.7	32.70 	2.40 	2.00 	II	68.40 	33.00 	49.93 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3375	UYB79189	Takayuki Katoh	EGFP 	2315885245	UGGUAGUGGUCGGCGAGCU	AGCUCGCCGACCACUACCA	-2.1	-2.10 	3.20 	2.00 	1.00 	5.00 	-44.7	44.80 	-3.60 	5.00 	II	63.20 	52.70 	64.64 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3376	UYB79189	Takayuki Katoh	EGFP 	2315885245	CUGGUAGUGGUCGGCGAGC	GCUCGCCGACCACUACCAG	-3.4	-2.10 	3.20 	-1.00 	0.00 	5.00 	-44.7	30.00 	3.10 	2.00 	II	68.40 	46.70 	34.38 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3377	UYB79189	Takayuki Katoh	EGFP 	2315885245	GCUGGUAGUGGUCGGCGAG	CUCGCCGACCACUACCAGC	-2.1	-3.40 	2.00 	-1.00 	1.00 	5.00 	-44.7	34.10 	5.40 	1.00 	II	68.40 	31.50 	32.31 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3378	UYB79189	Takayuki Katoh	EGFP 	2315885245	UGCUGGUAGUGGUCGGCGA	UCGCCGACCACUACCAGCA	-2.4	-2.10 	0.30 	2.00 	0.00 	5.00 	-44.7	50.00 	-3.80 	4.00 	II	63.20 	45.50 	74.12 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3379	UYB79189	Takayuki Katoh	EGFP 	2315885245	CUGCUGGUAGUGGUCGGCG	CGCCGACCACUACCAGCAG	-2.4	-2.10 	0.30 	0.00 	2.00 	5.00 	-44.4	39.20 	0.30 	2.00 	II	68.40 	52.00 	38.65 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3380	UYB79189	Takayuki Katoh	EGFP 	2315885245	UCUGCUGGUAGUGGUCGGC	GCCGACCACUACCAGCAGA	-3.4	-2.40 	0.60 	-1.00 	4.00 	4.00 	-44.4	52.60 	10.40 	5.00 	II	63.20 	59.10 	58.69 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3381	UYB79189	Takayuki Katoh	EGFP 	2315885245	UUCUGCUGGUAGUGGUCGG	CCGACCACUACCAGCAGAA	-3.3	-0.90 	1.40 	1.00 	4.00 	3.00 	-41.9	63.90 	2.30 	5.00 	Ib	57.90 	60.90 	78.21 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3382	UYB79189	Takayuki Katoh	EGFP 	2315885245	GUUCUGCUGGUAGUGGUCG	CGACCACUACCAGCAGAAC	-2.4	-2.20 	1.40 	2.00 	3.00 	2.00 	-40.8	51.00 	2.30 	3.00 	II	57.90 	50.20 	57.45 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3383	UYB79189	Takayuki Katoh	EGFP 	2315885245	UGUUCUGCUGGUAGUGGUC	GACCACUACCAGCAGAACA	-2.4	-2.10 	1.40 	-1.00 	3.00 	2.00 	-40.5	68.50 	7.80 	6.00 	Ib	52.60 	60.10 	77.82 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3384	UYB79189	Takayuki Katoh	EGFP 	2315885245	GUGUUCUGCUGGUAGUGGU	ACCACUACCAGCAGAACAC	-2.2	-2.20 	1.40 	2.00 	0.00 	2.00 	-40.3	64.30 	-4.00 	4.00 	II	52.60 	41.20 	79.21 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3385	UYB79189	Takayuki Katoh	EGFP 	2315885245	GGUGUUCUGCUGGUAGUGG	CCACUACCAGCAGAACACC	-3.3	-3.30 	1.40 	1.00 	2.00 	2.00 	-41.4	50.00 	2.30 	2.00 	II	57.90 	40.30 	52.61 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3386	UYB79189	Takayuki Katoh	EGFP 	2315885245	GGGUGUUCUGCUGGUAGUG	CACUACCAGCAGAACACCC	-2.1	-3.30 	1.40 	0.00 	0.00 	3.00 	-41.4	47.70 	0.70 	1.00 	II	57.90 	37.90 	46.68 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3387	UYB79189	Takayuki Katoh	EGFP 	2315885245	GGGGUGUUCUGCUGGUAGU	ACUACCAGCAGAACACCCC	-2.2	-3.30 	1.40 	1.00 	-2.00 	4.00 	-42.6	49.10 	-6.30 	1.00 	III	57.90 	32.20 	37.60 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3388	UYB79189	Takayuki Katoh	EGFP 	2315885245	GGGGGUGUUCUGCUGGUAG	CUACCAGCAGAACACCCCC	-2.1	-3.30 	1.90 	0.00 	0.00 	5.00 	-43.7	44.10 	4.70 	1.00 	II	63.20 	36.70 	53.07 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3389	UYB79189	Takayuki Katoh	EGFP 	2315885245	UGGGGGUGUUCUGCUGGUA	UACCAGCAGAACACCCCCA	-1.3	-2.10 		1.00 	-1.00 	5.00 	-43.7	43.40 	-3.10 	3.00 	II	57.90 	44.20 	64.58 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3390	UYB79189	Takayuki Katoh	EGFP 	2315885245	AUGGGGGUGUUCUGCUGGU	ACCAGCAGAACACCCCCAU	-2.2	-1.10 		1.00 	2.00 	5.00 	-43.5	40.80 	-6.30 	3.00 	II	57.90 	48.00 	55.93 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3391	UYB79189	Takayuki Katoh	EGFP 	2315885245	GAUGGGGGUGUUCUGCUGG	CCAGCAGAACACCCCCAUC	-3.3	-2.40 	3.50 	0.00 	3.00 	5.00 	-43.7	47.10 	7.80 	3.00 	II	63.20 	48.80 	37.82 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3392	UYB79189	Takayuki Katoh	EGFP 	2315885245	CGAUGGGGGUGUUCUGCUG	CAGCAGAACACCCCCAUCG	-2.1	-2.40 	1.80 	0.00 	0.00 	5.00 	-42.8	45.00 	1.00 	2.00 	II	63.20 	39.40 	30.49 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3393	UYB79189	Takayuki Katoh	EGFP 	2315885245	CCGAUGGGGGUGUUCUGCU	AGCAGAACACCCCCAUCGG	-2.1	-3.30 	0.70 	0.00 	-1.00 	5.00 	-44	42.10 	-3.60 	2.00 	III	63.20 	40.80 	28.80 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3394	UYB79189	Takayuki Katoh	EGFP 	2315885245	GCCGAUGGGGGUGUUCUGC	GCAGAACACCCCCAUCGGC	-3.4	-3.40 	0.30 	1.00 	1.00 	5.00 	-45.3	39.90 	15.50 	2.00 	II	68.40 	38.40 	29.42 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3395	UYB79189	Takayuki Katoh	EGFP 	2315885245	CGCCGAUGGGGGUGUUCUG	CAGAACACCCCCAUCGGCG	-2.1	-2.40 	0.30 	1.00 	-1.00 	5.00 	-44.3	32.60 	-2.00 	0.00 	II	68.40 	31.30 	53.10 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3396	UYB79189	Takayuki Katoh	EGFP 	2315885245	UCGCCGAUGGGGGUGUUCU	AGAACACCCCCAUCGGCGA	-2.1	-2.40 	0.30 	2.00 	1.00 	5.00 	-44.6	51.30 	-1.60 	4.00 	II	63.20 	54.10 	56.63 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3397	UYB79189	Takayuki Katoh	EGFP 	2315885245	GUCGCCGAUGGGGGUGUUC	GAACACCCCCAUCGGCGAC	-2.4	-2.20 	0.30 	-1.00 	0.00 	5.00 	-44.7	36.20 	7.40 	2.00 	II	68.40 	36.50 	33.82 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3398	UYB79189	Takayuki Katoh	EGFP 	2315885245	CGUCGCCGAUGGGGGUGUU	AACACCCCCAUCGGCGACG	-0.9	-2.40 	-0.80 	-1.00 	-2.00 	5.00 	-44.7	23.70 	-6.00 	0.00 	III	68.40 	16.90 	18.55 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3399	UYB79189	Takayuki Katoh	EGFP 	2315885245	CCGUCGCCGAUGGGGGUGU	ACACCCCCAUCGGCGACGG	-2.2	-3.30 	-2.10 	-1.00 	-3.00 	5.00 	-47.1	25.20 	-6.00 	1.00 	III	73.70 	26.70 	20.81 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3400	UYB79189	Takayuki Katoh	EGFP 	2315885245	GCCGUCGCCGAUGGGGGUG	CACCCCCAUCGGCGACGGC	-2.1	-3.40 	-2.50 	0.00 	0.00 	5.00 	-48.3	24.80 	5.30 	0.00 	II	78.90 	28.50 	19.37 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3401	UYB79189	Takayuki Katoh	EGFP 	2315885245	GGCCGUCGCCGAUGGGGGU	ACCCCCAUCGGCGACGGCC	-2.2	-3.30 	-3.00 	1.00 	-1.00 	5.00 	-49.5	19.30 	-4.00 	-2.00 	III	78.90 	18.30 	36.26 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3402	UYB79189	Takayuki Katoh	EGFP 	2315885245	GGGCCGUCGCCGAUGGGGG	CCCCCAUCGGCGACGGCCC	-3.3	-3.30 	-3.80 	3.00 	2.00 	6.00 	-50.6	24.70 	-2.60 	-1.00 	II	84.20 	34.90 	17.46 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3403	UYB79189	Takayuki Katoh	EGFP 	2315885245	GGGGCCGUCGCCGAUGGGG	CCCCAUCGGCGACGGCCCC	-3.3	-3.30 	-3.80 	1.00 	1.00 	7.00 	-50.6	20.70 	-4.70 	-1.00 	II	84.20 	33.60 	12.82 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3404	UYB79189	Takayuki Katoh	EGFP 	2315885245	CGGGGCCGUCGCCGAUGGG	CCCAUCGGCGACGGCCCCG	-3.3	-2.40 	-3.80 	-2.00 	0.00 	8.00 	-49.7	13.70 	-2.00 	-2.00 	II	84.20 	25.80 	3.78 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3405	UYB79189	Takayuki Katoh	EGFP 	2315885245	ACGGGGCCGUCGCCGAUGG	CCAUCGGCGACGGCCCCGU	-3.3	-2.20 	-3.80 	2.00 	2.00 	8.00 	-48.6	25.30 	0.10 	1.00 	II	78.90 	42.40 	10.21 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3406	UYB79189	Takayuki Katoh	EGFP 	2315885245	CACGGGGCCGUCGCCGAUG	CAUCGGCGACGGCCCCGUG	-2.1	-2.10 	-3.80 	0.00 	-1.00 	8.00 	-47.4	21.50 	-4.40 	0.00 	II	78.90 	43.30 	33.38 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3407	UYB79189	Takayuki Katoh	EGFP 	2315885245	GCACGGGGCCGUCGCCGAU	AUCGGCGACGGCCCCGUGC	-1.1	-3.40 	-3.80 	1.00 	-1.00 	8.00 	-48.7	13.60 	1.50 	0.00 	III	78.90 	19.20 	35.75 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3408	UYB79189	Takayuki Katoh	EGFP 	2315885245	AGCACGGGGCCGUCGCCGA	UCGGCGACGGCCCCGUGCU	-2.4	-2.10 	-3.80 	2.00 	0.00 	8.00 	-49.7	27.70 	-6.10 	2.00 	II	78.90 	35.00 	28.48 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3409	UYB79189	Takayuki Katoh	EGFP 	2315885245	CAGCACGGGGCCGUCGCCG	CGGCGACGGCCCCGUGCUG	-2.4	-2.10 	-3.80 	1.00 	2.00 	8.00 	-49.4	21.50 	-1.70 	1.00 	II	84.20 	45.60 	35.09 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3410	UYB79189	Takayuki Katoh	EGFP 	2315885245	GCAGCACGGGGCCGUCGCC	GGCGACGGCCCCGUGCUGC	-3.3	-3.40 	-3.50 	0.00 	2.00 	8.00 	-50.4	15.00 	7.50 	-1.00 	II	84.20 	29.70 	18.87 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3411	UYB79189	Takayuki Katoh	EGFP 	2315885245	AGCAGCACGGGGCCGUCGC	GCGACGGCCCCGUGCUGCU	-3.4	-2.10 	-3.00 	2.00 	3.00 	8.00 	-49.2	37.90 	9.80 	2.00 	II	78.90 	49.10 	42.04 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3412	UYB79189	Takayuki Katoh	EGFP 	2315885245	CAGCAGCACGGGGCCGUCG	CGACGGCCCCGUGCUGCUG	-2.4	-2.10 	-3.00 	1.00 	0.00 	8.00 	-47.9	26.60 	0.70 	1.00 	II	78.90 	43.90 	40.44 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3413	UYB79189	Takayuki Katoh	EGFP 	2315885245	GCAGCAGCACGGGGCCGUC	GACGGCCCCGUGCUGCUGC	-2.4	-3.40 	-3.00 	-1.00 	1.00 	8.00 	-48.9	15.20 	7.40 	0.00 	II	78.90 	28.80 	26.45 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3414	UYB79189	Takayuki Katoh	EGFP 	2315885245	GGCAGCAGCACGGGGCCGU	ACGGCCCCGUGCUGCUGCC	-2.2	-3.30 	-3.00 	0.00 	-1.00 	8.00 	-49.8	19.40 	-6.30 	1.00 	III	78.90 	27.00 	19.61 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3415	UYB79189	Takayuki Katoh	EGFP 	2315885245	GGGCAGCAGCACGGGGCCG	CGGCCCCGUGCUGCUGCCC	-2.4	-3.30 	-2.50 	1.00 	1.00 	8.00 	-50.9	8.70 	2.70 	-1.00 	II	84.20 	28.50 	14.04 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3416	UYB79189	Takayuki Katoh	EGFP 	2315885245	CGGGCAGCAGCACGGGGCC	GGCCCCGUGCUGCUGCCCG	-3.3	-2.40 	-1.70 	-2.00 	0.00 	7.00 	-50.9	15.50 	5.50 	-1.00 	II	84.20 	34.50 	21.14 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3417	UYB79189	Takayuki Katoh	EGFP 	2315885245	UCGGGCAGCAGCACGGGGC	GCCCCGUGCUGCUGCCCGA	-3.4	-2.40 	-0.60 	1.00 	3.00 	6.00 	-50	36.20 	2.50 	4.00 	II	78.90 	60.40 	36.52 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3418	UYB79189	Takayuki Katoh	EGFP 	2315885245	GUCGGGCAGCAGCACGGGG	CCCCGUGCUGCUGCCCGAC	-3.3	-2.20 	-0.60 	1.00 	2.00 	5.00 	-48.8	21.50 	4.70 	0.00 	II	78.90 	36.20 	48.29 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3419	UYB79189	Takayuki Katoh	EGFP 	2315885245	UGUCGGGCAGCAGCACGGG	CCCGUGCUGCUGCCCGACA	-3.3	-2.10 	-0.60 	1.00 	4.00 	5.00 	-47.6	27.80 	-2.40 	4.00 	II	73.70 	54.20 	38.55 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3420	UYB79189	Takayuki Katoh	EGFP 	2315885245	UUGUCGGGCAGCAGCACGG	CCGUGCUGCUGCCCGACAA	-3.3	-0.90 	-0.60 	0.00 	4.00 	5.00 	-45.2	49.50 	-4.90 	6.00 	II	68.40 	67.70 	77.17 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3421	UYB79189	Takayuki Katoh	EGFP 	2315885245	GUUGUCGGGCAGCAGCACG	CGUGCUGCUGCCCGACAAC	-2.4	-2.20 	-0.60 	1.00 	2.00 	5.00 	-44.1	43.00 	4.70 	3.00 	II	68.40 	48.20 	79.88 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3422	UYB79189	Takayuki Katoh	EGFP 	2315885245	GGUUGUCGGGCAGCAGCAC	GUGCUGCUGCCCGACAACC	-2.2	-3.30 	-0.60 	1.00 	1.00 	5.00 	-45	30.60 	5.10 	1.00 	II	68.40 	30.70 	62.46 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3423	UYB79189	Takayuki Katoh	EGFP 	2315885245	UGGUUGUCGGGCAGCAGCA	UGCUGCUGCCCGACAACCA	-2.1	-2.10 	-0.60 	1.00 	0.00 	5.00 	-44.9	46.80 	-8.70 	5.00 	II	63.20 	53.00 	86.83 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3424	UYB79189	Takayuki Katoh	EGFP 	2315885245	GUGGUUGUCGGGCAGCAGC	GCUGCUGCCCGACAACCAC	-3.4	-2.20 	-0.60 	1.00 	1.00 	5.00 	-45	46.50 	9.80 	2.00 	II	68.40 	50.90 	72.87 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3425	UYB79189	Takayuki Katoh	EGFP 	2315885245	AGUGGUUGUCGGGCAGCAG	CUGCUGCCCGACAACCACU	-2.1	-2.10 	2.00 	2.00 	3.00 	5.00 	-43.7	43.30 	0.00 	3.00 	Ib	63.20 	47.40 	54.20 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3426	UYB79189	Takayuki Katoh	EGFP 	2315885245	UAGUGGUUGUCGGGCAGCA	UGCUGCCCGACAACCACUA	-2.1	-1.30 	2.00 	1.00 	1.00 	5.00 	-42.9	47.30 	-6.10 	5.00 	II	57.90 	53.60 	56.72 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3427	UYB79189	Takayuki Katoh	EGFP 	2315885245	GUAGUGGUUGUCGGGCAGC	GCUGCCCGACAACCACUAC	-3.4	-2.20 	2.00 	-1.00 	2.00 	5.00 	-43	35.70 	5.10 	3.00 	II	63.20 	49.80 	50.43 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3428	UYB79189	Takayuki Katoh	EGFP 	2315885245	GGUAGUGGUUGUCGGGCAG	CUGCCCGACAACCACUACC	-2.1	-3.30 	2.00 	-1.00 	1.00 	5.00 	-42.9	42.80 	5.40 	2.00 	II	63.20 	31.10 	51.29 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3429	UYB79189	Takayuki Katoh	EGFP 	2315885245	AGGUAGUGGUUGUCGGGCA	UGCCCGACAACCACUACCU	-2.1	-2.10 	2.10 	3.00 	0.00 	5.00 	-42.9	47.50 	-1.10 	4.00 	II	57.90 	44.00 	61.02 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3430	UYB79189	Takayuki Katoh	EGFP 	2315885245	CAGGUAGUGGUUGUCGGGC	GCCCGACAACCACUACCUG	-3.4	-2.10 	3.00 	0.00 	2.00 	5.00 	-42.9	45.00 	10.80 	2.00 	II	63.20 	50.60 	52.66 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3431	UYB79189	Takayuki Katoh	EGFP 	2315885245	UCAGGUAGUGGUUGUCGGG	CCCGACAACCACUACCUGA	-3.3	-2.40 	1.90 	-1.00 	4.00 	4.00 	-41.9	53.70 	3.00 	4.00 	Ib	57.90 	61.20 	81.93 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3432	UYB79189	Takayuki Katoh	EGFP 	2315885245	CUCAGGUAGUGGUUGUCGG	CCGACAACCACUACCUGAG	-3.3	-2.10 	1.90 	1.00 	2.00 	3.00 	-40.7	58.50 	0.30 	2.00 	II	57.90 	49.90 	90.38 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3433	UYB79189	Takayuki Katoh	EGFP 	2315885245	GCUCAGGUAGUGGUUGUCG	CGACAACCACUACCUGAGC	-2.4	-3.40 	1.90 	1.00 	2.00 	2.00 	-40.8	45.40 	5.00 	3.00 	II	57.90 	43.80 	46.17 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3434	UYB79189	Takayuki Katoh	EGFP 	2315885245	UGCUCAGGUAGUGGUUGUC	GACAACCACUACCUGAGCA	-2.4	-2.10 	1.90 	-1.00 	2.00 	2.00 	-40.5	61.40 	10.40 	6.00 	II	52.60 	52.90 	52.40 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3435	UYB79189	Takayuki Katoh	EGFP 	2315885245	GUGCUCAGGUAGUGGUUGU	ACAACCACUACCUGAGCAC	-2.2	-2.20 	1.90 	1.00 	-1.00 	2.00 	-40.3	53.80 	-1.70 	4.00 	III	52.60 	36.10 	62.88 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3436	UYB79189	Takayuki Katoh	EGFP 	2315885245	GGUGCUCAGGUAGUGGUUG	CAACCACUACCUGAGCACC	-2.1	-3.30 	1.90 	1.00 	1.00 	2.00 	-41.4	45.70 	2.30 	1.00 	II	57.90 	38.50 	40.65 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3437	UYB79189	Takayuki Katoh	EGFP 	2315885245	GGGUGCUCAGGUAGUGGUU	AACCACUACCUGAGCACCC	-0.9	-3.30 	1.90 	0.00 	-2.00 	3.00 	-42.6	45.70 	-3.50 	1.00 	III	57.90 	27.60 	79.56 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3438	UYB79189	Takayuki Katoh	EGFP 	2315885245	UGGGUGCUCAGGUAGUGGU	ACCACUACCUGAGCACCCA	-2.2	-2.10 	1.90 	1.00 	1.00 	3.00 	-43.8	58.00 	-4.00 	4.00 	II	57.90 	54.10 	97.99 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3439	UYB79189	Takayuki Katoh	EGFP 	2315885245	CUGGGUGCUCAGGUAGUGG	CCACUACCUGAGCACCCAG	-3.3	-2.10 	-0.60 	-1.00 	1.00 	3.00 	-43.7	44.80 	2.60 	2.00 	II	63.20 	49.20 	75.84 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3440	UYB79189	Takayuki Katoh	EGFP 	2315885245	ACUGGGUGCUCAGGUAGUG	CACUACCUGAGCACCCAGU	-2.1	-2.20 	-1.20 	2.00 	3.00 	3.00 	-42.6	36.80 	-2.40 	2.00 	II	57.90 	46.50 	51.33 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3441	UYB79189	Takayuki Katoh	EGFP 	2315885245	GACUGGGUGCUCAGGUAGU	ACUACCUGAGCACCCAGUC	-2.2	-2.40 	-1.20 	0.00 	-1.00 	3.00 	-42.9	38.40 	-8.90 	1.00 	III	57.90 	34.10 	36.88 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3442	UYB79189	Takayuki Katoh	EGFP 	2315885245	GGACUGGGUGCUCAGGUAG	CUACCUGAGCACCCAGUCC	-2.1	-3.30 	-1.20 	1.00 	0.00 	3.00 	-44	40.00 	3.10 	2.00 	II	63.20 	37.40 	67.08 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3443	UYB79189	Takayuki Katoh	EGFP 	2315885245	CGGACUGGGUGCUCAGGUA	UACCUGAGCACCCAGUCCG	-1.3	-2.40 	-1.20 	0.00 	-4.00 	3.00 	-44.3	39.70 	-8.10 	0.00 	III	63.20 	26.60 	64.68 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3444	UYB79189	Takayuki Katoh	EGFP 	2315885245	GCGGACUGGGUGCUCAGGU	ACCUGAGCACCCAGUCCGC	-2.2	-3.40 	-1.20 	2.00 	0.00 	4.00 	-46.4	32.50 	3.50 	0.00 	III	68.40 	33.90 	69.96 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3445	UYB79189	Takayuki Katoh	EGFP 	2315885245	GGCGGACUGGGUGCUCAGG	CCUGAGCACCCAGUCCGCC	-3.3	-3.30 	-1.20 	1.00 	0.00 	5.00 	-47.5	27.70 	3.00 	-2.00 	II	73.70 	28.50 	40.62 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3446	UYB79189	Takayuki Katoh	EGFP 	2315885245	GGGCGGACUGGGUGCUCAG	CUGAGCACCCAGUCCGCCC	-2.1	-3.30 	-0.90 	0.00 	0.00 	6.00 	-47.5	25.80 	0.00 	0.00 	II	73.70 	30.20 	41.95 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3447	UYB79189	Takayuki Katoh	EGFP 	2315885245	AGGGCGGACUGGGUGCUCA	UGAGCACCCAGUCCGCCCU	-2.1	-2.10 	0.50 	2.00 	0.00 	6.00 	-47.5	36.20 	-1.40 	3.00 	II	68.40 	40.10 	49.79 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3448	UYB79189	Takayuki Katoh	EGFP 	2315885245	CAGGGCGGACUGGGUGCUC	GAGCACCCAGUCCGCCCUG	-2.4	-2.10 	-0.10 	-2.00 	0.00 	6.00 	-47.5	21.00 	5.40 	1.00 	II	73.70 	38.00 	44.88 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3449	UYB79189	Takayuki Katoh	EGFP 	2315885245	UCAGGGCGGACUGGGUGCU	AGCACCCAGUCCGCCCUGA	-2.1	-2.40 	-1.20 	0.00 	2.00 	6.00 	-47.5	30.00 	-3.30 	3.00 	II	68.40 	47.10 	43.21 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3450	UYB79189	Takayuki Katoh	EGFP 	2315885245	CUCAGGGCGGACUGGGUGC	GCACCCAGUCCGCCCUGAG	-3.4	-2.10 	-1.20 	-1.00 	0.00 	6.00 	-47.5	37.30 	5.40 	2.00 	II	73.70 	45.50 	64.82 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3451	UYB79189	Takayuki Katoh	EGFP 	2315885245	GCUCAGGGCGGACUGGGUG	CACCCAGUCCGCCCUGAGC	-2.1	-3.40 	-1.20 	2.00 	2.00 	6.00 	-47.5	28.50 	7.40 	1.00 	II	73.70 	34.50 	51.63 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3452	UYB79189	Takayuki Katoh	EGFP 	2315885245	UGCUCAGGGCGGACUGGGU	ACCCAGUCCGCCCUGAGCA	-2.2	-2.10 	-1.20 	1.00 	1.00 	6.00 	-47.5	41.80 	-6.60 	3.00 	II	68.40 	43.30 	51.85 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3453	UYB79189	Takayuki Katoh	EGFP 	2315885245	UUGCUCAGGGCGGACUGGG	CCCAGUCCGCCCUGAGCAA	-3.3	-0.90 	-1.20 	2.00 	4.00 	6.00 	-46.2	43.10 	-2.40 	4.00 	Ib	68.40 	64.40 	34.08 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3454	UYB79189	Takayuki Katoh	EGFP 	2315885245	UUUGCUCAGGGCGGACUGG	CCAGUCCGCCCUGAGCAAA	-3.3	-0.90 	-1.20 	0.00 	4.00 	6.00 	-43.8	49.10 	-2.40 	4.00 	Ib	63.20 	60.00 	73.77 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3455	UYB79189	Takayuki Katoh	EGFP 	2315885245	CUUUGCUCAGGGCGGACUG	CAGUCCGCCCUGAGCAAAG	-2.1	-2.10 	-0.90 	-1.00 	1.00 	6.00 	-42.6	51.90 	0.40 	3.00 	II	63.20 	46.20 	77.81 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3456	UYB79189	Takayuki Katoh	EGFP 	2315885245	UCUUUGCUCAGGGCGGACU	AGUCCGCCCUGAGCAAAGA	-2.1	-2.40 	-0.80 	1.00 	1.00 	6.00 	-42.9	61.90 	-4.00 	6.00 	II	57.90 	56.20 	83.90 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3457	UYB79189	Takayuki Katoh	EGFP 	2315885245	GUCUUUGCUCAGGGCGGAC	GUCCGCCCUGAGCAAAGAC	-2.2	-2.20 	-0.80 	-1.00 	1.00 	6.00 	-43	46.00 	9.70 	3.00 	II	63.20 	38.40 	80.58 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3458	UYB79189	Takayuki Katoh	EGFP 	2315885245	GGUCUUUGCUCAGGGCGGA	UCCGCCCUGAGCAAAGACC	-2.4	-3.30 	-0.80 	2.00 	-1.00 	6.00 	-44.1	32.90 	-6.10 	2.00 	II	63.20 	25.90 	54.93 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3459	UYB79189	Takayuki Katoh	EGFP 	2315885245	GGGUCUUUGCUCAGGGCGG	CCGCCCUGAGCAAAGACCC	-3.3	-3.30 	-0.80 	1.00 	1.00 	6.00 	-45	41.70 	-4.90 	1.00 	II	68.40 	40.30 	44.99 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3460	UYB79189	Takayuki Katoh	EGFP 	2315885245	GGGGUCUUUGCUCAGGGCG	CGCCCUGAGCAAAGACCCC	-2.4	-3.30 	-0.80 	1.00 	1.00 	5.00 	-45	46.90 	3.10 	1.00 	II	68.40 	44.70 	59.56 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3461	UYB79189	Takayuki Katoh	EGFP 	2315885245	UGGGGUCUUUGCUCAGGGC	GCCCUGAGCAAAGACCCCA	-3.4	-2.10 	-0.50 	0.00 	3.00 	4.00 	-44.7	53.00 	5.10 	2.00 	II	63.20 	56.50 	52.41 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3462	UYB79189	Takayuki Katoh	EGFP 	2315885245	UUGGGGUCUUUGCUCAGGG	CCCUGAGCAAAGACCCCAA	-3.3	-0.90 	0.50 	1.00 	5.00 	4.00 	-42.2	58.60 	4.70 	4.00 	II	57.90 	70.90 	80.40 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3463	UYB79189	Takayuki Katoh	EGFP 	2315885245	GUUGGGGUCUUUGCUCAGG	CCUGAGCAAAGACCCCAAC	-3.3	-2.20 	0.50 	1.00 	2.00 	4.00 	-41.1	47.60 	3.00 	2.00 	II	57.90 	47.70 	58.79 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3464	UYB79189	Takayuki Katoh	EGFP 	2315885245	CGUUGGGGUCUUUGCUCAG	CUGAGCAAAGACCCCAACG	-2.1	-2.40 	0.80 	-2.00 	0.00 	4.00 	-40.2	46.40 	1.00 	2.00 	II	57.90 	37.20 	50.17 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3465	UYB79189	Takayuki Katoh	EGFP 	2315885245	UCGUUGGGGUCUUUGCUCA	UGAGCAAAGACCCCAACGA	-2.1	-2.40 	2.70 	1.00 	0.00 	4.00 	-40.5	65.10 	-0.80 	7.00 	II	52.60 	53.10 	81.08 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3466	UYB79189	Takayuki Katoh	EGFP 	2315885245	CUCGUUGGGGUCUUUGCUC	GAGCAAAGACCCCAACGAG	-2.4	-2.10 		0.00 	1.00 	4.00 	-40.5	56.50 	5.40 	2.00 	II	57.90 	53.40 	79.64 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3467	UYB79189	Takayuki Katoh	EGFP 	2315885245	UCUCGUUGGGGUCUUUGCU	AGCAAAGACCCCAACGAGA	-2.1	-2.40 		3.00 	3.00 	4.00 	-40.5	68.70 	3.80 	5.00 	II	52.60 	57.90 	82.37 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3468	UYB79189	Takayuki Katoh	EGFP 	2315885245	UUCUCGUUGGGGUCUUUGC	GCAAAGACCCCAACGAGAA	-3.4	-0.90 		2.00 	3.00 	4.00 	-39.3	82.90 	7.40 	7.00 	Ib	52.60 	70.20 	92.10 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3469	UYB79189	Takayuki Katoh	EGFP 	2315885245	CUUCUCGUUGGGGUCUUUG	CAAAGACCCCAACGAGAAG	-2.1	-2.10 		0.00 	1.00 	4.00 	-38	64.50 	0.30 	5.00 	II	52.60 	51.40 	71.51 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3470	UYB79189	Takayuki Katoh	EGFP 	2315885245	GCUUCUCGUUGGGGUCUUU	AAAGACCCCAACGAGAAGC	-0.9	-3.40 		-1.00 	-2.00 	4.00 	-39.3	48.80 	-4.00 	3.00 	III	52.60 	23.00 	14.62 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3471	UYB79189	Takayuki Katoh	EGFP 	2315885245	CGCUUCUCGUUGGGGUCUU	AAGACCCCAACGAGAAGCG	-0.9	-2.40 	1.40 	0.00 	-3.00 	4.00 	-40.8	44.20 	-6.00 	2.00 	III	57.90 	29.10 	11.33 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3472	UYB79189	Takayuki Katoh	EGFP 	2315885245	GCGCUUCUCGUUGGGGUCU	AGACCCCAACGAGAAGCGC	-2.1	-3.40 	1.00 	1.00 	-2.00 	4.00 	-43.3	39.70 	-1.00 	1.00 	III	63.20 	31.50 	17.22 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3473	UYB79189	Takayuki Katoh	EGFP 	2315885245	CGCGCUUCUCGUUGGGGUC	GACCCCAACGAGAAGCGCG	-2.4	-2.40 	1.00 	-1.00 	-1.00 	5.00 	-43.6	49.30 	8.40 	0.00 	II	68.40 	38.10 	31.83 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3474	UYB79189	Takayuki Katoh	EGFP 	2315885245	UCGCGCUUCUCGUUGGGGU	ACCCCAACGAGAAGCGCGA	-2.2	-2.40 	0.60 	3.00 	2.00 	5.00 	-43.6	55.20 	-4.00 	3.00 	II	63.20 	51.00 	84.64 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3475	UYB79189	Takayuki Katoh	EGFP 	2315885245	AUCGCGCUUCUCGUUGGGG	CCCCAACGAGAAGCGCGAU	-3.3	-1.10 	0.60 	1.00 	5.00 	5.00 	-42.5	48.20 	0.00 	2.00 	II	63.20 	53.50 	84.64 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3476	UYB79189	Takayuki Katoh	EGFP 	2315885245	GAUCGCGCUUCUCGUUGGG	CCCAACGAGAAGCGCGAUC	-3.3	-2.40 	0.60 	0.00 	3.00 	5.00 	-41.6	43.80 	3.10 	2.00 	II	63.20 	36.90 	74.41 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3477	UYB79189	Takayuki Katoh	EGFP 	2315885245	UGAUCGCGCUUCUCGUUGG	CCAACGAGAAGCGCGAUCA	-3.3	-2.10 	0.60 	1.00 	3.00 	5.00 	-40.4	63.80 	-2.40 	5.00 	II	57.90 	60.10 	83.93 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3478	UYB79189	Takayuki Katoh	EGFP 	2315885245	GUGAUCGCGCUUCUCGUUG	CAACGAGAAGCGCGAUCAC	-2.1	-2.20 	0.60 	1.00 	1.00 	5.00 	-39.3	61.10 	7.80 	4.00 	II	57.90 	49.60 	78.72 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3479	UYB79189	Takayuki Katoh	EGFP 	2315885245	UGUGAUCGCGCUUCUCGUU	AACGAGAAGCGCGAUCACA	-0.9	-2.10 	0.60 	1.00 	1.00 	5.00 	-39.3	62.30 	-0.60 	5.00 	II	52.60 	52.20 	77.66 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3480	UYB79189	Takayuki Katoh	EGFP 	2315885245	AUGUGAUCGCGCUUCUCGU	ACGAGAAGCGCGAUCACAU	-2.2	-1.10 	0.60 	3.00 	3.00 	5.00 	-39.5	65.80 	-4.00 	5.00 	II	52.60 	55.10 	83.23 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3481	UYB79189	Takayuki Katoh	EGFP 	2315885245	CAUGUGAUCGCGCUUCUCG	CGAGAAGCGCGAUCACAUG	-2.4	-2.10 	0.90 	0.00 	2.00 	5.00 	-39.4	62.70 	0.40 	4.00 	II	57.90 	58.50 	82.60 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3482	UYB79189	Takayuki Katoh	EGFP 	2315885245	CCAUGUGAUCGCGCUUCUC	GAGAAGCGCGAUCACAUGG	-2.4	-3.30 	1.20 	-1.00 	0.00 	5.00 	-40.3	46.90 	3.10 	2.00 	II	57.90 	43.90 	58.75 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3483	UYB79189	Takayuki Katoh	EGFP 	2315885245	ACCAUGUGAUCGCGCUUCU	AGAAGCGCGAUCACAUGGU	-2.1	-2.20 	1.00 	1.00 	0.00 	5.00 	-40.1	54.90 	-3.90 	6.00 	II	52.60 	45.30 	47.59 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3484	UYB79189	Takayuki Katoh	EGFP 	2315885245	GACCAUGUGAUCGCGCUUC	GAAGCGCGAUCACAUGGUC	-2.4	-2.40 	-1.80 	2.00 	0.00 	5.00 	-40.4	50.10 	7.80 	3.00 	II	57.90 	49.20 	61.12 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3485	UYB79189	Takayuki Katoh	EGFP 	2315885245	GGACCAUGUGAUCGCGCUU	AAGCGCGAUCACAUGGUCC	-0.9	-3.30 	-2.60 	1.00 	-1.00 	5.00 	-41.3	42.60 	3.80 	0.00 	III	57.90 	30.90 	43.28 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3486	UYB79189	Takayuki Katoh	EGFP 	2315885245	AGGACCAUGUGAUCGCGCU	AGCGCGAUCACAUGGUCCU	-2.1	-2.10 	-2.60 	2.00 	1.00 	5.00 	-42.5	56.50 	-4.00 	2.00 	II	57.90 	48.20 	61.73 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3487	UYB79189	Takayuki Katoh	EGFP 	2315885245	CAGGACCAUGUGAUCGCGC	GCGCGAUCACAUGGUCCUG	-3.4	-2.10 	-2.60 	-1.00 	2.00 	5.00 	-42.5	41.00 	7.80 	0.00 	II	63.20 	50.70 	47.42 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3488	UYB79189	Takayuki Katoh	EGFP 	2315885245	GCAGGACCAUGUGAUCGCG	CGCGAUCACAUGGUCCUGC	-2.4	-3.40 	-2.60 	0.00 	2.00 	4.00 	-42.5	32.30 	3.00 	-1.00 	II	63.20 	34.60 	29.11 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3489	UYB79189	Takayuki Katoh	EGFP 	2315885245	AGCAGGACCAUGUGAUCGC	GCGAUCACAUGGUCCUGCU	-3.4	-2.10 	-2.60 	1.00 	3.00 	3.00 	-42.2	50.10 	7.40 	3.00 	II	57.90 	56.30 	38.65 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3490	UYB79189	Takayuki Katoh	EGFP 	2315885245	CAGCAGGACCAUGUGAUCG	CGAUCACAUGGUCCUGCUG	-2.4	-2.10 	-2.60 	1.00 	1.00 	2.00 	-40.9	52.90 	8.40 	2.00 	II	57.90 	53.40 	50.54 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3491	UYB79189	Takayuki Katoh	EGFP 	2315885245	CCAGCAGGACCAUGUGAUC	GAUCACAUGGUCCUGCUGG	-2.4	-3.30 	-2.30 	-2.00 	-1.00 	2.00 	-41.8	36.60 	3.10 	0.00 	II	57.90 	36.50 	62.90 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3492	UYB79189	Takayuki Katoh	EGFP 	2315885245	UCCAGCAGGACCAUGUGAU	AUCACAUGGUCCUGCUGGA	-1.1	-2.40 	-1.80 	1.00 	1.00 	2.00 	-41.8	57.00 	-8.90 	5.00 	II	52.60 	50.80 	76.45 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3493	UYB79189	Takayuki Katoh	EGFP 	2315885245	CUCCAGCAGGACCAUGUGA	UCACAUGGUCCUGCUGGAG	-2.4	-2.10 	-2.60 	1.00 	-3.00 	2.00 	-42.8	39.50 	-0.70 	1.00 	III	57.90 	33.70 	36.24 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3494	UYB79189	Takayuki Katoh	EGFP 	2315885245	ACUCCAGCAGGACCAUGUG	CACAUGGUCCUGCUGGAGU	-2.1	-2.20 	-2.60 	2.00 	3.00 	2.00 	-42.6	46.00 	2.40 	2.00 	II	57.90 	45.40 	78.82 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3495	UYB79189	Takayuki Katoh	EGFP 	2315885245	AACUCCAGCAGGACCAUGU	ACAUGGUCCUGCUGGAGUU	-2.2	-0.90 	-2.60 	2.00 	1.00 	2.00 	-41.4	68.00 	-6.60 	6.00 	II	52.60 	57.20 	56.39 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3496	UYB79189	Takayuki Katoh	EGFP 	2315885245	GAACUCCAGCAGGACCAUG	CAUGGUCCUGCUGGAGUUC	-2.1	-2.40 	-2.60 	2.00 	1.00 	2.00 	-41.6	42.10 	2.30 	1.00 	II	57.90 	42.60 	71.90 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3497	UYB79189	Takayuki Katoh	EGFP 	2315885245	CGAACUCCAGCAGGACCAU	AUGGUCCUGCUGGAGUUCG	-1.1	-2.40 	-2.60 	-2.00 	-2.00 	2.00 	-41.9	33.30 	-8.30 	0.00 	III	57.90 	27.30 	30.83 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3498	UYB79189	Takayuki Katoh	EGFP 	2315885245	ACGAACUCCAGCAGGACCA	UGGUCCUGCUGGAGUUCGU	-2.1	-2.20 	-2.60 	2.00 	0.00 	2.00 	-43	49.10 	-6.00 	4.00 	II	57.90 	49.70 	86.15 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3499	UYB79189	Takayuki Katoh	EGFP 	2315885245	CACGAACUCCAGCAGGACC	GGUCCUGCUGGAGUUCGUG	-3.3	-2.10 	-2.60 	0.00 	0.00 	2.00 	-43	45.50 	12.80 	0.00 	II	63.20 	46.70 	74.54 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3500	UYB79189	Takayuki Katoh	EGFP 	2315885245	UCACGAACUCCAGCAGGAC	GUCCUGCUGGAGUUCGUGA	-2.2	-2.40 	-2.60 	1.00 	3.00 	2.00 	-42.1	38.60 	5.10 	3.00 	Ib	57.90 	54.00 	44.11 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3501	UYB79189	Takayuki Katoh	EGFP 	2315885245	GUCACGAACUCCAGCAGGA	UCCUGCUGGAGUUCGUGAC	-2.4	-2.20 	-2.40 	0.00 	-1.00 	2.00 	-42.1	39.10 	-11.00 	1.00 	III	57.90 	34.50 	85.24 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3502	UYB79189	Takayuki Katoh	EGFP 	2315885245	GGUCACGAACUCCAGCAGG	CCUGCUGGAGUUCGUGACC	-3.3	-3.30 	-0.80 	1.00 	1.00 	2.00 	-43	37.20 	2.80 	2.00 	II	63.20 	39.60 	52.67 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3503	UYB79189	Takayuki Katoh	EGFP 	2315885245	CGGUCACGAACUCCAGCAG	CUGCUGGAGUUCGUGACCG	-2.1	-2.40 	0.30 	-1.00 	-1.00 	3.00 	-42.1	45.20 	1.10 	1.00 	II	63.20 	32.00 	75.73 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3504	UYB79189	Takayuki Katoh	EGFP 	2315885245	GCGGUCACGAACUCCAGCA	UGCUGGAGUUCGUGACCGC	-2.1	-3.40 	0.30 	1.00 	-2.00 	4.00 	-43.4	45.10 	-3.80 	2.00 	III	63.20 	37.80 	36.89 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3505	UYB79189	Takayuki Katoh	EGFP 	2315885245	GGCGGUCACGAACUCCAGC	GCUGGAGUUCGUGACCGCC	-3.4	-3.30 	0.30 	1.00 	1.00 	5.00 	-44.6	39.10 	14.40 	-1.00 	II	68.40 	39.50 	30.95 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3506	UYB79189	Takayuki Katoh	EGFP 	2315885245	CGGCGGUCACGAACUCCAG	CUGGAGUUCGUGACCGCCG	-2.1	-2.40 	0.30 	1.00 	-1.00 	6.00 	-43.6	31.70 	-4.60 	0.00 	II	68.40 	36.70 	39.76 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3507	UYB79189	Takayuki Katoh	EGFP 	2315885245	GCGGCGGUCACGAACUCCA	UGGAGUUCGUGACCGCCGC	-2.1	-3.40 	-0.10 	1.00 	-2.00 	7.00 	-44.9	30.00 	-8.70 	1.00 	III	68.40 	35.10 	32.90 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3508	UYB79189	Takayuki Katoh	EGFP 	2315885245	GGCGGCGGUCACGAACUCC	GGAGUUCGUGACCGCCGCC	-3.3	-3.30 	-0.90 	0.00 	0.00 	8.00 	-46.1	26.40 	7.40 	1.00 	II	73.70 	38.20 	40.14 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3509	UYB79189	Takayuki Katoh	EGFP 	2315885245	CGGCGGCGGUCACGAACUC	GAGUUCGUGACCGCCGCCG	-2.4	-2.40 	-0.90 	0.00 	-1.00 	9.00 	-45.2	13.50 	5.50 	-1.00 	II	73.70 	28.60 	28.30 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3510	UYB79189	Takayuki Katoh	EGFP 	2315885245	CCGGCGGCGGUCACGAACU	AGUUCGUGACCGCCGCCGG	-2.1	-3.30 	-1.30 	0.00 	-3.00 	10.00 	-46.1	23.50 	-10.90 	-1.00 	III	73.70 	38.20 	30.00 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3511	UYB79189	Takayuki Katoh	EGFP 	2315885245	CCCGGCGGCGGUCACGAAC	GUUCGUGACCGCCGCCGGG	-2.2	-3.30 	-2.60 	0.00 	-2.00 	11.00 	-47.3	26.80 	10.80 	-1.00 	II	78.90 	33.10 	33.47 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3512	UYB79189	Takayuki Katoh	EGFP 	2315885245	UCCCGGCGGCGGUCACGAA	UUCGUGACCGCCGCCGGGA	-0.9	-2.40 	-2.60 	2.00 	-1.00 	11.00 	-47.5	24.80 	-3.80 	1.00 	II	73.70 	29.80 	29.13 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3513	UYB79189	Takayuki Katoh	EGFP 	2315885245	AUCCCGGCGGCGGUCACGA	UCGUGACCGCCGCCGGGAU	-2.4	-1.10 	-2.60 	3.00 	2.00 	11.00 	-47.7	30.60 	-3.80 	2.00 	II	73.70 	43.90 	34.74 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3514	UYB79189	Takayuki Katoh	EGFP 	2315885245	GAUCCCGGCGGCGGUCACG	CGUGACCGCCGCCGGGAUC	-2.4	-2.40 	-2.60 	1.00 	2.00 	11.00 	-47.7	29.20 	-2.40 	1.00 	II	78.90 	39.20 	25.27 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3515	UYB79189	Takayuki Katoh	EGFP 	2315885245	UGAUCCCGGCGGCGGUCAC	GUGACCGCCGCCGGGAUCA	-2.2	-2.10 	-2.60 	0.00 	3.00 	11.00 	-47.4	42.50 	9.80 	3.00 	II	73.70 	44.60 	69.59 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3516	UYB79189	Takayuki Katoh	EGFP 	2315885245	GUGAUCCCGGCGGCGGUCA	UGACCGCCGCCGGGAUCAC	-2.1	-2.20 	-2.60 	1.00 	-2.00 	11.00 	-47.4	33.60 	-6.10 	2.00 	III	73.70 	32.30 	14.39 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3517	UYB79189	Takayuki Katoh	EGFP 	2315885245	AGUGAUCCCGGCGGCGGUC	GACCGCCGCCGGGAUCACU	-2.4	-2.10 	-2.60 	1.00 	3.00 	11.00 	-47.4	32.00 	7.80 	2.00 	Ib	73.70 	45.10 	30.53 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3518	UYB79189	Takayuki Katoh	EGFP 	2315885245	GAGUGAUCCCGGCGGCGGU	ACCGCCGCCGGGAUCACUC	-2.2	-2.40 	-2.60 	1.00 	0.00 	11.00 	-47.4	32.30 	-1.60 	1.00 	II	73.70 	30.20 	57.62 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3519	UYB79189	Takayuki Katoh	EGFP 	2315885245	AGAGUGAUCCCGGCGGCGG	CCGCCGCCGGGAUCACUCU	-3.3	-2.10 	-2.10 	2.00 	4.00 	11.00 	-47.3	35.00 	-2.40 	3.00 	Ib	73.70 	54.30 	26.93 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3520	UYB79189	Takayuki Katoh	EGFP 	2315885245	GAGAGUGAUCCCGGCGGCG	CGCCGCCGGGAUCACUCUC	-2.4	-2.40 	-1.00 	-1.00 	2.00 	10.00 	-46.4	26.80 	-4.70 	1.00 	II	73.70 	42.70 	32.57 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3521	UYB79189	Takayuki Katoh	EGFP 	2315885245	CGAGAGUGAUCCCGGCGGC	GCCGCCGGGAUCACUCUCG	-3.4	-2.40 	-3.40 	-1.00 	1.00 	9.00 	-46.4	25.20 	5.80 	1.00 	II	73.70 	38.90 	47.36 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3522	UYB79189	Takayuki Katoh	EGFP 	2315885245	CCGAGAGUGAUCCCGGCGG	CCGCCGGGAUCACUCUCGG	-3.3	-3.30 	-6.60 	0.00 	0.00 	8.00 	-46.3	30.70 	-2.00 	1.00 	II	73.70 	42.60 	29.72 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3523	UYB79189	Takayuki Katoh	EGFP 	2315885245	GCCGAGAGUGAUCCCGGCG	CGCCGGGAUCACUCUCGGC	-2.4	-3.40 	-10.10 	0.00 	1.00 	7.00 	-46.4	32.10 	10.40 	0.00 	II	73.70 	40.30 	31.46 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3524	UYB79189	Takayuki Katoh	EGFP 	2315885245	UGCCGAGAGUGAUCCCGGC	GCCGGGAUCACUCUCGGCA	-3.4	-2.10 	-11.50 	2.00 	3.00 	6.00 	-46.1	38.80 	7.40 	2.00 	II	68.40 	53.10 	15.45 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3525	UYB79189	Takayuki Katoh	EGFP 	2315885245	AUGCCGAGAGUGAUCCCGG	CCGGGAUCACUCUCGGCAU	-3.3	-1.10 	-6.80 	2.00 	5.00 	5.00 	-43.8	45.60 	-0.30 	2.00 	II	63.20 	63.20 	25.13 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3526	UYB79189	Takayuki Katoh	EGFP 	2315885245	CAUGCCGAGAGUGAUCCCG	CGGGAUCACUCUCGGCAUG	-2.4	-2.10 	-4.40 	0.00 	2.00 	4.00 	-42.6	49.70 	1.00 	2.00 	II	63.20 	52.90 	31.76 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3527	UYB79189	Takayuki Katoh	EGFP 	2315885245	CCAUGCCGAGAGUGAUCCC	GGGAUCACUCUCGGCAUGG	-3.3	-3.30 	-2.40 	-2.00 	1.00 	4.00 	-43.5	41.40 	7.70 	0.00 	II	63.20 	39.50 	24.37 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3528	UYB79189	Takayuki Katoh	EGFP 	2315885245	UCCAUGCCGAGAGUGAUCC	GGAUCACUCUCGGCAUGGA	-3.3	-2.40 	1.00 	1.00 	3.00 	4.00 	-42.6	62.30 	9.70 	6.00 	II	57.90 	65.60 	62.83 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3529	UYB79189	Takayuki Katoh	EGFP 	2315885245	GUCCAUGCCGAGAGUGAUC	GAUCACUCUCGGCAUGGAC	-2.4	-2.20 	0.80 	1.00 	0.00 	4.00 	-41.5	45.60 	9.80 	2.00 	II	57.90 	44.00 	26.06 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3530	UYB79189	Takayuki Katoh	EGFP 	2315885245	CGUCCAUGCCGAGAGUGAU	AUCACUCUCGGCAUGGACG	-1.1	-2.40 	0.80 	2.00 	-2.00 	4.00 	-41.5	40.60 	-6.00 	1.00 	III	57.90 	28.00 	21.86 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3531	UYB79189	Takayuki Katoh	EGFP 	2315885245	UCGUCCAUGCCGAGAGUGA	UCACUCUCGGCAUGGACGA	-2.4	-2.40 	-0.90 	0.00 	-1.00 	4.00 	-42.8	48.20 	-8.70 	5.00 	II	57.90 	44.60 	11.37 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3532	UYB79189	Takayuki Katoh	EGFP 	2315885245	CUCGUCCAUGCCGAGAGUG	CACUCUCGGCAUGGACGAG	-2.1	-2.10 	-3.50 	-1.00 	0.00 	4.00 	-42.5	38.90 	-6.70 	0.00 	II	63.20 	43.50 	25.11 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3533	UYB79189	Takayuki Katoh	EGFP 	2315885245	GCUCGUCCAUGCCGAGAGU	ACUCUCGGCAUGGACGAGC	-2.2	-3.40 	-3.90 	0.00 	-1.00 	4.00 	-43.8	32.10 	-3.90 	-1.00 	III	63.20 	21.50 	9.14 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3534	UYB79189	Takayuki Katoh	EGFP 	2315885245	AGCUCGUCCAUGCCGAGAG	CUCUCGGCAUGGACGAGCU	-2.1	-2.10 	-3.90 	3.00 	2.00 	4.00 	-43.7	56.60 	2.40 	3.00 	II	63.20 	51.30 	60.36 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3535	UYB79189	Takayuki Katoh	EGFP 	2315885245	CAGCUCGUCCAUGCCGAGA	UCUCGGCAUGGACGAGCUG	-2.4	-2.10 	-3.90 	1.00 	-3.00 	4.00 	-43.7	45.90 	-0.40 	1.00 	III	63.20 	37.10 	83.09 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3536	UYB79189	Takayuki Katoh	EGFP 	2315885245	ACAGCUCGUCCAUGCCGAG	CUCGGCAUGGACGAGCUGU	-2.1	-2.20 	-3.80 	0.00 	3.00 	4.00 	-43.5	37.70 	-2.40 	1.00 	II	63.20 	42.60 	33.35 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3537	UYB79189	Takayuki Katoh	EGFP 	2315885245	UACAGCUCGUCCAUGCCGA	UCGGCAUGGACGAGCUGUA	-2.4	-1.30 	-3.50 	2.00 	2.00 	4.00 	-42.7	57.50 	-8.70 	4.00 	II	57.90 	56.70 	66.79 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3538	UYB79189	Takayuki Katoh	EGFP 	2315885245	GUACAGCUCGUCCAUGCCG	CGGCAUGGACGAGCUGUAC	-2.4	-2.20 	-3.40 	2.00 	3.00 	4.00 	-42.5	41.10 	2.80 	1.00 	II	63.20 	51.50 	56.75 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3539	UYB79189	Takayuki Katoh	EGFP 	2315885245	UGUACAGCUCGUCCAUGCC	GGCAUGGACGAGCUGUACA	-3.3	-2.10 	-1.60 	0.00 	4.00 	3.00 	-42.2	66.00 	12.80 	4.00 	Ib	57.90 	62.40 	73.66 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3540	UYB79189	Takayuki Katoh	EGFP 	2315885245	UUGUACAGCUCGUCCAUGC	GCAUGGACGAGCUGUACAA	-3.4	-0.90 	-0.50 	1.00 	3.00 	2.00 	-39.8	73.70 	7.80 	8.00 	Ia	52.60 	72.50 	76.68 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3541	UYB79189	Takayuki Katoh	EGFP 	2315885245	CUUGUACAGCUCGUCCAUG	CAUGGACGAGCUGUACAAG	-2.1	-2.10 	0.60 	0.00 	1.00 	2.00 	-38.5	49.50 	-2.00 	3.00 	II	52.60 	48.00 	53.54 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3542	UYB79189	Takayuki Katoh	EGFP 	2315885245	ACUUGUACAGCUCGUCCAU	AUGGACGAGCUGUACAAGU	-1.1	-2.20 	-0.20 	0.00 	1.00 	2.00 	-38.6	59.40 	-0.90 	5.00 	II	47.40 	42.20 	68.43 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3543	UYB79189	Takayuki Katoh	EGFP 	2315885245	UACUUGUACAGCUCGUCCA	UGGACGAGCUGUACAAGUA	-2.1	-1.30 	-0.90 	2.00 	1.00 	2.00 	-38.8	80.60 	-6.10 	8.00 	II	47.40 	66.20 	82.90 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26
MC3544	UYB79189	Takayuki Katoh	EGFP 	2315885245	UUACUUGUACAGCUCGUCC	GGACGAGCUGUACAAGUAA	-3.3	-0.90 	-0.90 	1.00 	5.00 	2.00 	-37.6	82.80 	14.40 	8.00 	Ia	47.40 	79.60 	83.47 	Luciferase reporter assay	HeLa	150nM	72h	"Specific residues at every third position of siRNA shape its efficient RNAi activity.
shape its efficient RNAi activity"	17259216	2007	Nucleic Acids Research	2007/1/26