Detail Information
P450 protein:
| P450 Symbol | gcoA |
| Protein name | Aromatic O-demethylase, cytochrome P450 subunit |
| Uniprot ID | P0DPQ7 |
| Gene ID | / |
| Species | Amycolatopsis sp. (strain ATCC 39116 / 75iv2) |
| Txid | 385957 |
| P450 protein structure | AlphaFold ; PDBe |
| Subcellular location | / |
| Protein Sequence |
Reaction:
| Reaction type | Decomposition |
| Reaction site | O-CH3 |
Anisole gcoA 
Phenol |
Substrate Information:
| Substrate Name | Anisole |
| Substrate Chemical Formula | C7H8O |
| Substrate PubChem CID | 7519 |
| Substrate PubChem SID | / |
| Substrate Smiles | COC1=CC=CC=C1 |
| Substrate Structure |
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Product Information:
| Product Name | Phenol |
| Product Chemical Formula | C6H6O |
| Product PubChem CID | 996 |
| Product PubChem SID | / |
| Product Smiles | C1=CC=C(C=C1)O |
| Product Structure |
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References:
| Title: | A promiscuous cytochrome P450 aromatic O-demethylase for lignin bioconversion. |
| PMID: | 29950589 |
| Journal: | Nature communications |
| Year: | 2018/6/27 |